CN110731934A - 一种清白牙膏及其制备方法 - Google Patents

一种清白牙膏及其制备方法 Download PDF

Info

Publication number
CN110731934A
CN110731934A CN201911264097.6A CN201911264097A CN110731934A CN 110731934 A CN110731934 A CN 110731934A CN 201911264097 A CN201911264097 A CN 201911264097A CN 110731934 A CN110731934 A CN 110731934A
Authority
CN
China
Prior art keywords
toothpaste
whitening toothpaste
raw materials
preparation
whitening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201911264097.6A
Other languages
English (en)
Inventor
周燕萍
毛建林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Qingxin Health Technology Co Ltd
Original Assignee
Suzhou Qingxin Health Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou Qingxin Health Technology Co Ltd filed Critical Suzhou Qingxin Health Technology Co Ltd
Priority to CN201911264097.6A priority Critical patent/CN110731934A/zh
Publication of CN110731934A publication Critical patent/CN110731934A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • A61K8/025Explicitly spheroidal or spherical shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24Phosphorous; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25Silicon; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26Aluminium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/463Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/412Microsized, i.e. having sizes between 0.1 and 100 microns

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)

Abstract

本发明公开了一种清白牙膏,其特征在于:该牙膏包括以下重量百分比的配方原料:竹炭0.01‑0.1%、植酸钠1%‑5%、羟基磷灰石1‑5%、木糖醇1‑5%、二氧化硅10‑25%、山梨醇40‑70%、月桂醇硫酸酯钠1.8‑2.5%、聚乙二醇1‑5%、卡拉胶0.1‑0.5%、羟甲基纤维素0.1‑0.5%、电气石0.1‑5%、三氯蔗糖0.1‑2%、甘草提取物0.1‑1%、聚乙二醇1‑3%、磷酸三钠0.1‑0.3%、香精0.6‑1.5%、薄荷酮甘油缩酮0.1‑0.5%、透明质酸钠0.01‑0.2%、1,2‑己二醇0.1‑0.5%、辛甘醇0.1‑0.5%、对羟基苯乙酮0.1‑0.5%、云母0.1‑2%、余量为水。本发明从去除牙齿外源色斑,清除口腔异味提供解决方案,净白牙齿,清新口气,科学、安全、有效。

Description

一种清白牙膏及其制备方法
技术领域
本发明属于牙膏技术领域,更具体地说,特别涉及一种具备净白清口气效果的清白牙膏及其制备方法。
背景技术
牙膏是和牙刷一起用于清洁牙齿,保护口腔卫生,对人体安全的一种日用必需品。
随着人们生活水平的提高,对牙膏的质量需求也逐步提高。在性能方面一般要求牙膏:(1)能够去除牙齿表面的薄膜和菌斑而不损伤牙釉质和牙本质;(2)具有良好的清洁口腔及其周围的作用;(3)无毒性,对口腔粘膜无刺激;(4)有舒适的香味和口味,使用后有凉爽清新。
发明内容
本发明所要解决的技术问题是:提供一种具备净白牙齿、清新口气的清白牙膏及其制备方法,以满足随着不同人群的需求。
为了达到上述技术效果,本发明采用的技术方案是:
一种清白牙膏,该牙膏包括以下重量百分比的配方原料:竹炭0.01-0.1%、植酸钠1%-5%、羟基磷灰石1-5%、木糖醇1-5%、二氧化硅10-25%、山梨醇40-70%、月桂醇硫酸酯钠1.8-2.5%、聚乙二醇1-5%、卡拉胶0.1-0.5%、羟甲基纤维素0.1-0.5%、电气石0.1-5%、三氯蔗糖0.1-2%、甘草提取物0.1-1%、聚乙二醇1-3%、磷酸三钠0.1-0.3%、香精0.6-1.5%、薄荷酮甘油缩酮0.1-0.5%、透明质酸钠0.01-0.2%、1,2-己二醇0.1-0.5%、辛甘醇0.1-0.5%、对羟基苯乙酮0.1-0.5%、云母0.1-2%、余量为水。
进一步地,所述二氧化硅为球形二氧化硅,其粒径为0.5-50μm。
进一步地,所述羟基磷灰石的粒径为0.05-50μm。
一种清白牙膏的制备方法,包括以下制备步骤:
1).根据配方原料按重量百分比分别称重,然后依次将称重后的原料添加入预分散釜中,对添加的原料进行分散、混合操作10-15min;
2).开启制膏釜真空泵,将步骤1)中分散、混合后的液料吸入,然后开启刮刀、搅拌器及胶体磨进行搅拌操作40-60min;
3).对完成搅拌操作后的步骤2)中制膏釜真空泵进行破真空操作,将制膏釜真空泵内膏体取出,得到清口气美白牙膏,完成洁白牙膏的制备;
进一步地,步骤1)中的原料分散、混合均为常温状态下进行,时间为10min。
进一步地,步骤2)中以常温状态下通过刮刀、搅拌器及胶体磨进行搅拌操作50min。
与现有技术相比,本发明的有益效果是:
本发明与传统牙膏的不同主要改进就在于配方的不同,本发明通过使用植酸钠、羟基磷灰石、碧玺、竹炭、甘草提取物,透明质酸钠,球形二氧化硅多种物质按照一定的比例进行组合形成具有净白牙齿、清新口气的组合物,而且这些组合物可应用但不限于成人口腔产品。通过天然植酸钠去除牙齿外源性色素净白牙齿;羟基磷灰石、甘草牙釉质修护坚固牙齿,碧玺(电气石)释放负离子净化口腔,竹炭的超强吸附起到清新口气的效果,而且透明质酸钠口腔护理活性因子保湿护龈,维护口腔组织,健康口腔,高清洁型球形二氧化硅比普通高清洁二氧化硅更具清洁力;本发明所制备的洁白牙膏在科学、安全的基础上可有效去除牙齿外源色斑,清除口腔异味,持久清新,而且齿缝清洁更彻底,口腔更洁净,达到净白、清口气的效果。
具体实施方式
下面结合实施例对本发明的实施方式作进一步详细描述。以下实施例用于说明本发明,但不能用来限制本发明的范围。
一种清白牙膏及其制备方法,该牙膏包括以下重量百分比的配方原料:竹炭0.01-0.1%、植酸钠1%-5%、羟基磷灰石1-5%、木糖醇1-5%、二氧化硅10-25%、山梨醇40-70%、月桂醇硫酸酯钠1.8-2.5%、聚乙二醇1-5%、卡拉胶0.1-0.5%、羟甲基纤维素0.1-0.5%、电气石0.1-5%、三氯蔗糖0.1-2%、甘草提取物0.1-1%、聚乙二醇1-3%、磷酸三钠0.1-0.3%、香精0.6-1.5%、薄荷酮甘油缩酮0.1-0.5%、透明质酸钠0.01-0.2%、1,2-己二醇0.1-0.5%、辛甘醇0.1-0.5%、对羟基苯乙酮0.1-0.5%、云母0.1-2%、余量为水。其中,二氧化硅为球形二氧化硅,其粒径为0.5-50μm;羟基磷灰石的粒径为0.05-50μm。制备时,先根据配方原料按重量百分比分别称重,然后依次将称重后的原料添加入预分散釜中,对添加的原料进行分散、混合操作10-15min;再开启制膏釜真空泵,将分散、混合后的液料吸入,开启刮刀、搅拌器及胶体磨进行搅拌操作40-60min;对完成搅拌操作后对制膏釜真空泵进行破真空操作,将制膏釜真空泵内膏体取出,得到清口气美白牙膏,完成洁白牙膏的制备;
本发明与传统牙膏的不同主要改进就在于配方的不同,本发明针对牙齿及口腔特点,从去除牙齿外源色斑,清除口腔异味方面提供解决方案,刷选有效去渍净白成分精心复配清新成分达到净白、清口气效果,科学、安全、有效;通过添加植物来源净白因子植酸钠辅配牙釉质修护成分HAP(羟基磷灰石),双重净白牙齿,持久清新;添加碧玺、植物来源竹炭辅配甘草提取物有效吸附口腔异味,净白牙齿,持久清新;粒径为0.5-50μm的球形二氧化硅深入齿缝清洁更彻底,口腔更洁净,较小粒径的二氧化硅也对阻塞牙本质小管起到缓解牙齿敏感的作用。而粒径为0.05-50μm的羟基磷灰石有利于帮助牙本质片进行生物矿化,修复牙本质片,缩小牙小管孔径,甚至堵塞牙本质小管或在牙本质表面上沉积羟基磷灰石层,达到修补和加固牙齿的作用。
本发明不局限于上述具体的实施方式,对于本领域的普通技术人员来说从上述构思出发,不经过创造性的劳动,所作出的种种变换,均落在本发明的保护范围之内。

Claims (6)

1.一种清白牙膏,其特征在于:该牙膏包括以下重量百分比的配方原料:竹炭0.01-0.1%、植酸钠1%-5%、羟基磷灰石1-5%、木糖醇1-5%、二氧化硅10-25%、山梨醇40-70%、月桂醇硫酸酯钠1.8-2.5%、聚乙二醇1-5%、卡拉胶0.1-0.5%、羟甲基纤维素0.1-0.5%、电气石0.1-5%、三氯蔗糖0.1-2%、甘草提取物0.1-1%、聚乙二醇1-3%、磷酸三钠0.1-0.3%、香精0.6-1.5%、薄荷酮甘油缩酮0.1-0.5%、透明质酸钠0.01-0.2%、1,2-己二醇0.1-0.5%、辛甘醇0.1-0.5%、对羟基苯乙酮0.1-0.5%、云母0.1-2%、余量为水。
2.如权利要求1所述一种清白牙膏,其特征在于:所述二氧化硅为球形二氧化硅,其粒径为0.5-50μm。
3.如权利要求1所述一种清白牙膏,其特征在于:所述羟基磷灰石的粒径为0.05-50μm。
4.如权利要求1所述一种清白牙膏的制备方法,其特征在于:包括以下制备步骤:
1).根据配方原料按重量百分比分别称重,然后依次将称重后的原料添加入预分散釜中,对添加的原料进行分散、混合操作10-15min;
2).开启制膏釜真空泵,将步骤1)中分散、混合后的液料吸入,然后开启刮刀、搅拌器及胶体磨进行搅拌操作40-60min;
3).对完成搅拌操作后的步骤2)中制膏釜真空泵进行破真空操作,将制膏釜真空泵内膏体取出,得到清口气美白牙膏,完成洁白牙膏的制备。
5.如权利要求4所述一种清白牙膏的制备方法,其特征在于:步骤1)中的原料分散、混合均为常温状态下进行,时间为10min。
6.如权利要求4所述一种清白牙膏的制备方法,其特征在于:步骤2)中以常温状态下通过刮刀、搅拌器及胶体磨进行搅拌操作50min。
CN201911264097.6A 2019-12-11 2019-12-11 一种清白牙膏及其制备方法 Pending CN110731934A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201911264097.6A CN110731934A (zh) 2019-12-11 2019-12-11 一种清白牙膏及其制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201911264097.6A CN110731934A (zh) 2019-12-11 2019-12-11 一种清白牙膏及其制备方法

Publications (1)

Publication Number Publication Date
CN110731934A true CN110731934A (zh) 2020-01-31

Family

ID=69274561

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201911264097.6A Pending CN110731934A (zh) 2019-12-11 2019-12-11 一种清白牙膏及其制备方法

Country Status (1)

Country Link
CN (1) CN110731934A (zh)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022157636A1 (en) * 2021-01-20 2022-07-28 Karpinska Trojanowska Malgorzata Whitening toothpaste and method for producing the same
CN115040460A (zh) * 2022-07-12 2022-09-13 苏州清馨健康科技有限公司 一种用于美白牙齿的口腔清护牙膏及其制备方法
CN117323241A (zh) * 2023-10-24 2024-01-02 金三江(肇庆)硅材料股份有限公司 一种口腔用二氧化硅颗粒及其制备方法和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102125507A (zh) * 2010-01-18 2011-07-20 南京泽恒医药技术开发有限公司 一种含甘草提取物具有生物粘附功能的口腔用品组合物
CN106389235A (zh) * 2016-12-01 2017-02-15 广州中汉口腔用品有限公司 一种口气清新美白牙膏及其制作工艺
CN108670872A (zh) * 2018-08-16 2018-10-19 苏州清馨健康科技有限公司 清口气牙膏
CN108721190A (zh) * 2018-08-16 2018-11-02 苏州清馨健康科技有限公司 竹炭清新净白牙膏

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102125507A (zh) * 2010-01-18 2011-07-20 南京泽恒医药技术开发有限公司 一种含甘草提取物具有生物粘附功能的口腔用品组合物
CN106389235A (zh) * 2016-12-01 2017-02-15 广州中汉口腔用品有限公司 一种口气清新美白牙膏及其制作工艺
CN108670872A (zh) * 2018-08-16 2018-10-19 苏州清馨健康科技有限公司 清口气牙膏
CN108721190A (zh) * 2018-08-16 2018-11-02 苏州清馨健康科技有限公司 竹炭清新净白牙膏

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022157636A1 (en) * 2021-01-20 2022-07-28 Karpinska Trojanowska Malgorzata Whitening toothpaste and method for producing the same
CN115040460A (zh) * 2022-07-12 2022-09-13 苏州清馨健康科技有限公司 一种用于美白牙齿的口腔清护牙膏及其制备方法
CN117323241A (zh) * 2023-10-24 2024-01-02 金三江(肇庆)硅材料股份有限公司 一种口腔用二氧化硅颗粒及其制备方法和应用
CN117323241B (zh) * 2023-10-24 2024-05-28 金三江(肇庆)硅材料股份有限公司 一种口腔用二氧化硅颗粒及其制备方法和应用

Similar Documents

Publication Publication Date Title
CN110731934A (zh) 一种清白牙膏及其制备方法
de Moraes Rego Roselino et al. Color stability and surface roughness of composite resins submitted to brushing with bleaching toothpastes: An in situ study
CN1750807A (zh) 抗过敏性、抗龋齿、抗污迹、抗斑块、超温和的口腔卫生剂
CN107625659B (zh) 一种美白牙膏及其制备方法
US20150238399A1 (en) Tooth whitening composition
CN110051559A (zh) 藻酸盐洁牙剂组合物及其制备方法
CN108685763A (zh) 一种多重抗敏牙膏
CN108030749B (zh) 一种医用海藻牙膏
JP5303180B2 (ja) 歯の小柱間隙再形成用組成物
CN111000772A (zh) 化橘红提取物的新用途
CN108743424B (zh) 一种用于牙齿再矿化的口腔护理组合物
CN105658194A (zh) 洁齿剂组合物
CN113749970A (zh) 一种含有超氧化歧化酶sod促进牙齿洁白牙膏及其制备方法
CN108721190A (zh) 竹炭清新净白牙膏
CN110755337A (zh) 一种抗敏感修护牙膏
JP2008201732A (ja) 歯の美白方法
CN101305969B (zh) 一种口腔消毒卫生用品
CN108524290A (zh) 牙科预防龋齿组合物及其制备方法
CN107028791A (zh) 一种含小苏打的口腔护理组合物和应用,及含小苏打的牙膏
CN101909596A (zh) 用于牙齿组织再矿化的凝胶
KR20110129046A (ko) 기능성 치약조성물
CN108743419A (zh) 抗菌除渍牙膏
CN103957879B (zh) 口腔用组合物
CN106265327B (zh) 口腔护理组合物
EP4014955A1 (en) Toothpaste for preventing cold teeth and periodontal diseases and manufacturing method therefor

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20200131

RJ01 Rejection of invention patent application after publication