CN110694166B - Enteral administration system - Google Patents
Enteral administration system Download PDFInfo
- Publication number
- CN110694166B CN110694166B CN201910977416.1A CN201910977416A CN110694166B CN 110694166 B CN110694166 B CN 110694166B CN 201910977416 A CN201910977416 A CN 201910977416A CN 110694166 B CN110694166 B CN 110694166B
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- China
- Prior art keywords
- tablet
- tablet body
- colonoscope
- chuck
- hanging piece
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1042—Alimentary tract
- A61M2210/1067—Anus
Abstract
The invention discloses an enteral administration method, which comprises the following steps of S1: preparing a colonoscope, a biological clamp and an indwelling tablet; step S2: hanging the hanging piece on the biological clamp and keeping the hanging piece in a closed state, so that the tablet body is positioned at the front end of the colonoscope; step S3: the tablet body is sent into the intestinal canal from the anus through the colonoscope, and the intestinal wall is clamped through the biological clamp when the tablet body reaches the upper part of the lesion part, so that the tablet body is hung on the colon wall through the hanging piece; step S4: the colonoscope is withdrawn and the dosing is completed. The tablet can be left in the human intestine, thereby continuously exerting the drug effect on a specific part, being beneficial to reducing the drug dosage and side effect, improving the treatment efficiency and relieving the pain of patients.
Description
Technical Field
The invention belongs to the field of medical treatment, and particularly relates to an enteral administration method.
Background
Chronic nonspecific ulcerative colitis (ulcerative colitis, UC) is a chronic nonspecific inflammation mainly affecting the mucous membrane and submucosa of rectum and colon, and has clinical manifestations of abdominal pain, diarrhea, mucous and bloody stool and tenesmus, the course of disease is not cured, and can be as long as more than ten years or even decades, and the possibility of canceration also exists; the disease belongs to the categories of 'remote bowel', 'diarrhea' and 'dysentery' in the traditional Chinese medicine, and has complex etiology, long course of disease and difficult cure. The common medicine for treating ulcerative colitis is amino salicylic acid, sometimes hormone or immunosuppressant is used, the medicine has great side effect, the patient has poor compliance, the condition is delayed and not healed, and the life quality of the patient is seriously affected.
At present, in the aspect of the application of ulcerative colitis, oral administration or rectal administration is generally adopted; although the oral administration mode is simple and convenient, the production cost of the medicine is low, the medicine absorption is slow and irregular, the medicine effect is easily influenced by the gastrointestinal function and the gastrointestinal content, the medicine dosage is large, and the adverse stimulation effect on the gastrointestinal tract is easily generated; rectal administration, such as embolization or enema, is a topical mode of administration that is superior to systemic administration by delivering the drug through the anus into the intestine, through rapid absorption through the rectal mucosa into the general circulation, reducing the dosage and side effects, but rectal administration requires professional assistance, especially for moderate and severe ulcerative colitis, and requires multiple procedures, with low treatment efficiency and increased patient suffering.
Disclosure of Invention
In view of the above, it is an object of the present invention to provide an enteral administration method which allows a tablet to be left in the human intestine to exert an effect on a specific site continuously, is advantageous in reducing the dose of the drug and side effects, and can improve the treatment efficiency and alleviate the pain of a patient.
The invention provides an enteral administration method, which comprises the following steps:
step S1: preparing a colonoscope, a biological clamp and an indwelling tablet; the colonoscope is provided with a forceps channel and a control handle; the biological clamp is provided with a chuck, a control tube and an operating handle, the control tube penetrates into the clamp channel, and the chuck is arranged at the tail end of the control tube and is of a separable structure; the indwelling tablet comprises a tablet body and a hanging piece arranged on the tablet body;
step S2: hanging the hanging piece to the chuck, wherein the chuck is in a closed state, so that the tablet body is positioned at the front end of the colonoscope;
step S3: the tablet body is sent into the intestinal canal from the anus through the colonoscope, and when the tablet body reaches the upper part of a lesion part, the tablet body is controlled by the operating handle and the control tube to tightly grasp the colon wall and then release and separate, so that the chuck is fixed on the colon wall, and the tablet body is hung on the colon wall through the hanging piece;
step S4: the colonoscope is withdrawn and the dosing is completed.
Further, the hanging piece comprises an inner part fixed in the tablet body and an outer part penetrating out of the tablet body, the inner part is connected with the outer part, and the outer part and the edge of the tablet body form a closed graph.
Further, the hanging piece is made of a wire body, and two ends of the wire body penetrate through the center of the tablet body.
Further, the tablet body is of a controlled release tablet structure.
Further, the tablet body is circular, oval or strip-shaped.
Compared with the prior art, the enteral administration method of the invention can cause the tablet to be left in the human intestine, thereby continuously exerting the drug effect on the specific part, being beneficial to reducing the drug dosage and side effect, improving the treatment efficiency and relieving the pain of patients.
Drawings
FIG. 1 is a flow chart of a method of enteral administration according to the invention;
FIG. 2 is a view of an enteral administration method according to the invention;
FIG. 3 is an enlarged view taken at A in FIG. 2;
FIG. 4 is a schematic view of the structure of an indwelling tablet of the present invention.
Detailed Description
In order to make the technical solutions of the present invention better understood, the following detailed description of the present invention is provided with reference to the accompanying drawings and specific examples.
As shown in fig. 1 to 3, the present embodiment provides an enteral administration method including the steps of:
step S1: a colonoscope 3, a biological clamp 4 and indwelling tablets are prepared.
The colonoscope 3 is provided with a forceps channel 31 and a control handle 32, and the colonoscope 3 is of the same structure as the prior art.
The biological clamp 4 is provided with a clamping head 41, a control tube 42 and an operating handle 43, the control tube 42 penetrates into the forceps channel 31, the clamping head 41 is arranged at the tail end of the control tube 42 and is of a separable structure, and the biological clamp 4 of the structure is the same as the technology, such as shown in patent CN 104688293A or patent CN 208693379U. The collet 41 is preferably of a degradable construction that degrades itself when the tablet is fully released.
As shown in fig. 4, the indwelling tablet includes a tablet body 1 and a hanger 2 provided on the tablet body 1 to be hung on the colon wall of the human body. The tablet body 1 may be circular, oval or bar-shaped, consistent with existing tablets. The main component of the tablet body 1 depends on its effect, and when used for treating ulcerative colitis, the main component of the tablet body 1 may be 5-aminosalicylic acid. The tablet body 1 is preferably a controlled release tablet structure, which allows the drug to be released out of the tablet at a constant rate. Because the hanging piece 2 is additionally arranged, the tablet can be left in the intestines of a human body through the hanging piece 2, thereby continuously exerting the drug effect on a specific part, being beneficial to reducing the drug dosage and side effect, simultaneously improving the treatment efficiency and relieving the pain of a patient. In this embodiment, the hanger 2 includes an inner portion 21 fixed inside the tablet body 1 and an outer portion 22 penetrating out of the tablet body 1, the inner portion 21 is connected to the outer portion 22, and the outer portion 22 and the edge of the tablet body 1 form a closed pattern. The outer part 22 is mainly used as a hanging part, for example, in a ring structure, and the inner part 21 is used to fixedly connect the outer part 22 with the tablet body 1. The sheet inner portion 21 and the sheet outer portion 22 may be integrally provided. Preferably, the hanger 2 is made of a wire body, and the wire body can be a medical suture or a medical metal wire and can be a degradable structure; both ends of the wire body penetrate through the center of the tablet body 1, so that the retention time of the tablet can be prolonged to the maximum extent; the two ends of the wire body can be free ends, and can be connected to make the wire body in a ring shape; the line body can be in tablet body 1 press forming's in-process embedding tablet body 1, only need add relevant wire casing in the shaping groove of tablet this moment can, through the tablet press with the pendant suppression in tablet body 1 promptly.
Step S2: the hanger 2 is hung at the clip 41 with the clip 41 in the closed state, so that the tablet body 1 is positioned at the front end of the colonoscope 31. The clamping head 41 has two clamping pieces which can move oppositely or oppositely, and the movement of the clamping pieces can be controlled by the operating handle 43 and the control tube 42 to complete the clamping or opening operation; because the out-of-tablet part 22 of the hanger 2 bag and the edge of the tablet body 1 form a closed figure, a structure similar to a hanging ring is formed, and the hanger 2 can be directly hung on one of the clamping sheets; the insertion tube is at the front end of the colonoscope 31.
Step S3: when the tablet body 1 is fed into the intestinal canal 5 from the anus through the colonoscope 31 and reaches the upper part of the lesion, the clamping head 41 is controlled by the operating handle 43 and the control tube 42 to grasp the colon wall and then release and separate, so that the clamping head 41 is fixed on the colon wall, and the tablet body 1 is hung on the colon wall through the hanging piece 2, so that the tablet is left in the human intestine to continuously exert the drug effect on the specific part; FIG. 4 is a schematic illustration of this step, after the clamp 41 is released and ready to clamp the intestinal wall; the forward end of the colonoscope 31 may also be provided with a camera for viewing the intestinal conditions from the outside during its movement.
Step S4: the colonoscope 31 is withdrawn and the administration is completed.
Finally, the principle and embodiments of the present invention are explained by using specific examples, and the above descriptions of the examples are only used to help understand the core idea of the present invention, and the present invention can be modified and modified without departing from the principle of the present invention, and the modified and modified examples also fall into the protection scope of the present invention.
Claims (1)
1. An enteral administration system characterized by: comprises a colonoscope, a biological clamp and an indwelling tablet; the colonoscope is provided with a forceps channel and a control handle; the biological clamp is provided with a chuck, a control tube and an operating handle, the control tube penetrates into the clamp channel, and the chuck is arranged at the tail end of the control tube and is of a separable structure; the indwelling tablet comprises a tablet body and a hanging piece arranged on the tablet body; the hanger is used for hanging the chuck; the operation handle and the control tube are used for controlling the chuck to tightly grasp the colon wall and then release and separate, so that the chuck is fixed on the colon wall;
the hanging piece comprises an inner part fixed in the tablet body and an outer part penetrating out of the tablet body, the inner part is connected with the outer part, and the outer part and the edge of the tablet body form a closed graph;
the hanging piece is made of a wire body, and two ends of the wire body penetrate through the center of the tablet body;
the tablet body is of a controlled release tablet structure;
the tablet body is round, oval or strip-shaped;
the chuck is of a degradable structure; the line body is a medical suture or a medical metal wire, and both can be degradable structures.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201910977416.1A CN110694166B (en) | 2019-10-15 | 2019-10-15 | Enteral administration system |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201910977416.1A CN110694166B (en) | 2019-10-15 | 2019-10-15 | Enteral administration system |
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CN110694166A CN110694166A (en) | 2020-01-17 |
CN110694166B true CN110694166B (en) | 2021-09-28 |
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Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1078912A (en) * | 1992-05-18 | 1993-12-01 | 王庆书 | Internal positioner for medical medicine |
WO2009091478A1 (en) * | 2008-01-14 | 2009-07-23 | Boston Scientific Scimed, Inc. | Targeted therapeutic agent release for weight loss therapy |
WO2010116312A1 (en) * | 2009-04-07 | 2010-10-14 | Koninklijke Philips Electronics N.V. | Modular ingestible drug delivery capsule |
CN201612936U (en) * | 2010-03-05 | 2010-10-27 | 钟永祥 | Gynecological external pill |
CN102920418A (en) * | 2012-10-24 | 2013-02-13 | 刘思德 | Self-stable patency capsule of alimentary canal |
CN203873726U (en) * | 2014-04-03 | 2014-10-15 | 宁波贝思转化医学研究中心有限公司 | Implanted type wireless gastroenteric function detection system |
CN104688293A (en) * | 2015-02-15 | 2015-06-10 | 建德市康华医疗器材有限公司 | Detachable tissue holder and working method thereof |
CN208693379U (en) * | 2017-09-26 | 2019-04-05 | 庄则豪 | A kind of Gastrointestinal Endoscopes both arms protractor |
-
2019
- 2019-10-15 CN CN201910977416.1A patent/CN110694166B/en active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1078912A (en) * | 1992-05-18 | 1993-12-01 | 王庆书 | Internal positioner for medical medicine |
WO2009091478A1 (en) * | 2008-01-14 | 2009-07-23 | Boston Scientific Scimed, Inc. | Targeted therapeutic agent release for weight loss therapy |
WO2010116312A1 (en) * | 2009-04-07 | 2010-10-14 | Koninklijke Philips Electronics N.V. | Modular ingestible drug delivery capsule |
CN201612936U (en) * | 2010-03-05 | 2010-10-27 | 钟永祥 | Gynecological external pill |
CN102920418A (en) * | 2012-10-24 | 2013-02-13 | 刘思德 | Self-stable patency capsule of alimentary canal |
CN203873726U (en) * | 2014-04-03 | 2014-10-15 | 宁波贝思转化医学研究中心有限公司 | Implanted type wireless gastroenteric function detection system |
CN104688293A (en) * | 2015-02-15 | 2015-06-10 | 建德市康华医疗器材有限公司 | Detachable tissue holder and working method thereof |
CN208693379U (en) * | 2017-09-26 | 2019-04-05 | 庄则豪 | A kind of Gastrointestinal Endoscopes both arms protractor |
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Inventor after: Ma Ye Inventor after: Other inventor requests not to publish the name Inventor before: Request for anonymity |
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Effective date of registration: 20210913 Address after: 712100 unit 2, building 3, Weishui Jiayuan, Yangling Demonstration Zone, Xianyang City, Shaanxi Province Applicant after: Ma Ye Address before: 401120 no.599 Baosheng Avenue, Yubei District, Chongqing Applicant before: Liu Shanping |
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