CN110680308A - Electrocardiosignal denoising method based on fusion of improved EMD and threshold method - Google Patents
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Abstract
The invention provides an electrocardiosignal denoising method based on the fusion of an improved EMD (empirical mode decomposition) method and a threshold method, and belongs to the technical field of signal filtering. The method solves the problem of modal aliasing by superposing white noise with different weight coefficients, solves the problem of end points by a method of a least square support vector machine, constructs upper and lower envelope lines of a signal by a method of conformal spline interpolation, constructs cubic spline interpolation with second-order approximation accuracy, less segmentation and small operand by a conformal segmentation method, can inhibit the overshoot/undershoot problem of envelope fitting, provides a criterion of IMF component screening termination by the orthogonality and energy properties of the decomposed IMF, ensures the orthogonality and completeness of EMD decomposition, judges the number of noise contained in the screened IMF signal by the principle of mutual information to determine whether to filter the IMF signal, and increases the rapidity of an EMD algorithm; the threshold function is improved, and the threshold function combines the advantages of soft and hard thresholds to filter IMFs containing noise.
Description
Technical Field
The invention relates to an electrocardiosignal denoising method, in particular to an electrocardiosignal denoising method based on the fusion of an improved EMD and a threshold method, and belongs to the technical field of signal filtering.
Background
The electrocardiosignal is a typical unsteady and weak bioelectric signal and is widely applied to diagnosis and treatment of various heart diseases. The electrocardiosignals are often accompanied by very serious high-frequency and low-frequency noises, and the noise frequency band is often overlapped with the electrocardiosignal frequency band, so that the filtering pretreatment is difficult.
Conventional biomedical signal processing is primarily based on fourier theory. Fourier signal processing techniques are almost irreplaceable in the field of signal spectrum analysis and its associated signal processing fields such as data compression, signal detection, filtering, etc. However, the integral interval of the fourier transform is from positive infinity to negative infinity, and it cannot obtain the frequency spectrum content of the signal in a certain period of time. Due to the excellent time-frequency analysis characteristic and the capability of processing non-stationary random signals, the wavelet transform becomes an effective method for processing biomedical signals such as electrocardio and the like. Also, EMD has begun to be applied in the biomedical processing field due to its good adaptability in analyzing nonlinear and non-stationary signals. Such as electrocardiogram signal analysis, blood pressure signal de-noising, heartbeat signal analysis, etc., have been successfully applied.
Empirical Mode Decomposition (EMD) decomposes a signal into a sum of finite eigenmode functions (IMFs). The EMD decomposition fully considers the local scale characteristics of the signal, and each IMF component obtained in the way represents one scale characteristic of the original signal and contains the real physical information of the original signal. As a new self-adaptive signal time-frequency processing method, the EMD has wide application in the aspects of mechanical fault diagnosis, feature extraction, geophysical detection, medical analysis and the like, and the EMD method is also expanded to the field of two-dimensional signal processing. The method is well applied to the fields of less image edge detection, texture analysis, image fusion, image compression, image filtering and the like, and the effectiveness of the EMD is demonstrated.
The current EMD method has some defects and needs further research. Such as: the method comprises the following steps of research on an EMD quick algorithm, EMD modal aliasing problems, end point effects, envelope fitting problems of signals and criterion research on IMF component screening termination. In the method, the decomposition result directly influenced by the quality of the fitting of the envelope curve is completed by taking the extreme point as a known point in the original method adopting cubic spline function interpolation, and the fitting of the non-uniform point is caused by the non-uniformity of the distribution of the extreme point, so that the problem of extreme value undershoot or overshoot is caused, and a large error of decomposition is caused. The modal aliasing problem is a problem often encountered during EMD use, which is mainly caused by both intermittent events and signal interactions.
Aiming at the defects, the invention provides an electrocardiosignal denoising method based on the fusion of improved EMD and a threshold value method, and aims to improve the quality of the empirical mode decomposition of the electrocardiosignal and improve the effect of removing noise.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide an improved EMD and threshold fusion technology to decompose electrocardiosignals and remove noise of the electrocardiosignals. The method solves the problem of modal aliasing by superposing white noise with different weight coefficients, solves the problem of end points by a method of a least square support vector machine, constructs upper and lower envelope lines of a signal by a method of conformal spline interpolation, and constructs cubic spline interpolation with second-order approximation precision, less segmentation and small operand by a conformal segmentation method. By means of orthogonality and energy properties of the decomposed IMF, a criterion of 'screening' termination of IMF components is provided, and orthogonality and completeness of EMD decomposition are guaranteed. The screened IMF signals are judged to contain noise according to the principle of mutual information to decide whether to carry out filtering processing on the IMF signals, and therefore the rapidity of the EMD algorithm is greatly improved. And an improved threshold function is provided, which combines the advantages of soft and hard thresholds to filter the IMF containing noise.
The invention aims to solve the problem of modal aliasing caused by EMD decomposition, and provides an electrocardiosignal denoising method based on the fusion of improved EMD and a threshold value method.
An electrocardiosignal denoising method based on the fusion of an improved EMD and a threshold method comprises the following steps:
step 1: performing improved EMD decomposition on the electrocardiosignal;
step 1.1: the method of adding white noise to a cardiac electrical signal can be expressed as:
wherein,representing the signal after the positive coefficient white noise is added to the electrocardiosignal for the a time;representing the signal after negative coefficient white noise corresponding to the positive coefficient is added to the electrocardiosignal for the a time; y (t) represents the cardiac signal; n (t) represents white noise with a mean of zero and unit variance; omegaaIs a weightAnd (4) the coefficient. The following steps 1.2 to 1.5 are processing methods for adding the positive coefficient white noise, and similarly, the processing method for adding the negative coefficient white noise only needs to change the "+" mark to the "-" mark, and the meaning indicates the corresponding situation for adding the negative coefficient white noise.
Step 1.2: in order to avoid the phenomenon of two-end divergence during signal interpolation fitting, namely an end effect. Extending two ends of the signal by using a least square support vector machine; the signal processed in step 1.1 is sampled, first, the signal is sampledSampling is carried out, and the signal sampling sequence isAnd N is the number of sampling points. The training sample set is A { (h)1,g1),(h2,g2),···,(hl,gl) }, wherein: h isiIn order to input the vector, the vector is input,giin order to output the vector, the vector is,i is more than or equal to 1 and less than or equal to l; l is the number of training sample sets; test sample set B { (h)N-S+1,gN-S+1),(hN-S+2,gN-S+2),···,(hN,gN) }, wherein: s is more than or equal to 1 and is the number of test samples;
the output of the least squares support vector machine isWherein,for the first signal after continuation, it will beAs new boundary points of the original data, in the same wayObtaining the extension value of the 2 nd data sequenceBy analogy, all continuation sequences can be obtained according to the number of data points needing to be prolongedWherein M is the number of signal points extended right, the left extension method for a given data sequence is the same as the right extension method, and the left extension sequence is recorded as:the final extended sequence is noted
Step 1.3: and constructing upper and lower envelope lines of the signal by a conformal spline interpolation method.
Step 1.3.1: sequence Z (t) obtained by comparison of step 1.2i) The relationship between the size of a certain point and the size of the adjacent points to judge whether the point is an extreme point. The specific operation is as follows:
If it isThen point is reachedIs a minimum point.
When judging other points than the above-mentioned end points:
if it isI is more than or equal to M +1 and less than or equal to N + M-1, then pointIs the maximum point.
If it isI is more than or equal to M +1 and less than or equal to N + M-1, then pointIs a minimum point.
{xmax(t0),xmax(t1),...,xmax(tb) B is the number of maximum points;
the minimum point sequence is:
{xmin(t0),xmin(t1),...,xmin(tc) Where c is the number of maxima points.
Step 1.3.2: the upper envelope is constructed by the maximum point.
Two value points are inserted between every two maximum value points, and the definition is as follows:
wherein, tijTo be at time ti-1And tiThe j-th insertion point in between.
The sequences after insertion of the numerical points were:
{xmax(t0),xmax(t11),xmax(t12),xmax(t1),xmax(t21),xmax(t22),xmax(t3),...,xmax(tb)}
taking the above sequence as the control vertex of the T-B spline curve, the upper envelope curve, i.e. the T-B spline curve, can be expressed as follows:
wherein j represents the fitted j-th section of the T-B spline curve; u represents an upper envelope; h isij(T) is a T-B spline basis function when fitting T0To t1When a curve is segmented, hijThe expression of (t) is as follows:
wherein:
fitting t1:t2、t2:t3、···、tb-1:tbWhen a curve is segmented, hijThe expression of (t) is similar to that described above.
Step 1.3.3: the lower envelope is constructed by minimum points, the construction method is similar to the method for constructing the upper envelope, and the expression of the lower envelope is as follows:
wherein D represents a lower envelope;
step 1.4: averaging the upper envelope and the lower envelope:
wherein m isa(t) is the average of the upper and lower envelope lines obtained after the positive coefficient white noise is added for the a-th time;
if C (t) does not meet the IMF defined cutoff condition, repeating step 1.3; otherwise, extracting C (t) as Adding IMF of positive coefficient white noise decomposed by the ith EMD for the ith; residual amount of
Step 1.5: and (3) taking the residual amount r (t) in the step 1.4 as a new signal, namely r (t) ═ y (t), and then screening through the steps 1.1 to 1.4 to obtain the next lower-frequency IMF, and stopping screening until the screened IMF component meets the following rule.
The stopping criteria for the termination of the IMF component "screening" are:
wherein: IMFi(t) is the IMF of the ith EMD decomposition, and n is the IMFi(t) length;
when ZSD < θ, sieving is stopped, preferably θ is 0.03.
Step 1.6: the signal after the above decomposition can be expressed as the following formula:
wherein: d is the number of IMFs after EMD decomposition of the electrocardiosignals,adding IMF, r of positive coefficient white noise subjected to I EMD decomposition to the ad(t) is the residual error in the d-th decomposition.
Similar to the step 1.1 to the step 1.5, the EMD decomposition after adding the white noise with the negative coefficient to the electrocardiosignal is calculated, and the decomposed signal can be expressed as the following formula:
wherein,the i-th EMD decomposed IMF with negative coefficient white noise was added for the a-th time.
Step 1.7: accumulating and averaging the IMF added with the white noise of the positive coefficient and the negative coefficient obtained in the step 1.6 to obtain:
wherein:
step 2: judging the linear relation between each IMF and the original signal through arranging mutual information, and judging the effective signal of the IMF obtained in the step 1, wherein the formula is as follows:
QI(IMF(k),y)=S(IMF(k))+S(y)-S(IMF(k),y) (13)
wherein: s (IMF)(k)) And S (y) are respectively IMF(k)(t) and y (t) entropy of alignment, S (IMF)(k)) The calculation formula is as follows:
wherein p (-) represents the joint probability density of the permutation (-), and the calculation formula is as follows:
where i ═ 1,2, ·, n- (d-1) τ, n is the length of the time sequence, d is the given embedding dimension, τ is the time delay; # denotes the number of elements in the set,is IMF(k)Is arranged in (pi) with respect toi) (ii) a Arrangement (n)i) Representing time series IMF(k)(t) mapping to a d-dimensional space and then mapping each state vector to a corresponding permutation sequence;
suppose a time series { IMF(k)(t) maps to d-dimensional phase space, defining its joint state vector as:
the state vector is used for representing the track of the ith time sequence, and a track state matrix mapped to a state space can be obtained through the definition:
obtaining an arrangement sequence by comparing the magnitude relation of the adjacent values of the row vector of each state matrix, namely obtaining an arrangement matrix of the track matrix:
s (y) and S (IMF)(k)) The calculation of (a) is similar.
S(IMF(k)Y) represents IMF(k)(t) and y (t) joint permutation entropy, the calculation formula is as follows:
wherein p (pi)i,πj) Represents arrangement (pi)i,πj) The calculation formula is as follows:
where the subscript i ═ 1,2,. cndot.n- (d-1) τ,a pair of state space trajectory matrices, the corresponding arrangement of which is (pi)i,πj) (ii) a Arrangement (n)i,πj) Representation of IMF(k)(t) and y (t) an arrangement order corresponding to each state vector after the time series is mapped to the d-dimensional space, which is expressed as follows: suppose a time series { IMF(k)(t) and { y (t) } are mapped to d-dimensional phase space, defining its joint state matrix as:
the state vector is used for representing the track of the ith time sequence, and a track-like matrix mapped to the state space can be obtained through the definition:
obtaining an arrangement sequence by comparing the magnitude relation of the adjacent values of the row vector of each state matrix, namely obtaining an arrangement matrix of the track matrix:
and judging the degree of noise interference of each IMF according to the QI value of the mutual information of each IMF and the original signal, wherein the more the noise quantity is, the smaller the QI value is. And selecting the IMF with a small obvious QI value for denoising.
And step 3: carrying out threshold denoising processing on the IMF which is selected in the step 2 and needs to be denoised, wherein the threshold formula is as follows:
wherein: adjustable parameterThe adjustable parameter alpha is a positive number, and the adjustable parameter m is a positive number; threshold lambda1The calculation formula of (a) is as follows:
threshold valueσ is the standard deviation of noise in each IMF component, σ ═ mean (IMF)i) 0.6745, median (-) is the median;
threshold lambda2The calculation formula of (a) is as follows:
and 4, step 4: and (3) performing signal reconstruction on the IMF left in the step (2) and the signal processed in the step (3), wherein a calculation formula is as follows:
where y' (t) represents the denoised signal.
So far, the electrocardiosignal denoising process based on the fusion of the improved EMD and the threshold value method is completed from the step 1 to the step 4.
Advantageous effects
Compared with the prior art, the electrocardiosignal denoising method based on the fusion of the improved EMD and the threshold method has the following beneficial effects:
1. the method effectively solves the problem of mode aliasing caused by the interaction of two signals in the EMD by adopting a method of respectively adding positive white noise and negative white noise with different weight coefficients for multiple times, and improves the frequency resolution of the algorithm (the frequency resolution refers to the capability of distinguishing two adjacent frequency components);
2. the method uses a least square support vector machine method to carry out continuation and windowing on the signal, thereby avoiding the distortion phenomenon caused by the adoption of a cubic spline interpolation method to carry out fitting on the signal during decomposition;
3. the method uses a conformal spline interpolation method to construct the upper envelope line and the lower envelope line of a signal, and utilizes a conformal segmentation method to construct a cubic spline interpolation method with second-order approximation accuracy, less segmentation and small operand to inhibit overshoot/undershoot problems of envelope fitting, thereby avoiding the problem that interpolation errors caused by the traditional interpolation method are continuously accumulated along with the continuous proceeding of a decomposition process to cause serious errors.
4. The method directly adopts a threshold value method to denoise the IMF, and the method effectively reduces the operation time. The threshold function is improved, the details and the edge characteristics of the useful signal are better reserved by the threshold function, an effective signal is better provided on the basis of realizing signal noise reduction, the amplitude of the signal is guaranteed, the denoising effect is improved, and the operation time is reduced.
5. The method has simple flow and easy realization, and can be used for the design work of related software in the field of electrocardiosignal analysis.
Drawings
FIG. 1 is a schematic representation of the steps of the present invention;
FIG. 2 is a flow chart of the present invention;
FIG. 3 is a detailed diagram of the EMD decomposition of the present invention;
Detailed Description
The invention is explained in detail below with reference to the figures and examples, but the specific embodiments of the invention are not limited thereto.
The data in the embodiment are derived from the sampling data of the patient in the cardiovascular medical department of the general hospital of people liberation of China, an electrocardiograph is adopted to acquire the electrocardiosignal of the patient, the signal duration is 5s, the sampling frequency is 360Hz, and the electrocardiosignal data of the patient under the condition of daily free activity (non-violent movement) is acquired.
The embodiment explains a process of applying the electrocardiosignal denoising method based on the fusion of the improved EMD and the threshold value method to an electrocardiosignal denoising scene.
Fig. 1 is a schematic diagram of the steps of the method, and fig. 2 is a specific flowchart, and it can be seen from the diagram that the electrocardiosignal is firstly collected, and then the following steps are carried out:
step A: performing improved EMD on the acquired signals; fig. 3 is a detailed diagram of the EMD decomposition of the present invention, which is specifically as follows:
step A1: adding positive omega to the acquired signal y (t)1White noise n (t) with a zero mean value and unit variance;
in the embodiment, the white noise amplitude is 0.05 times of standard deviation of the electrocardiosignal, i.e. ω10.5, the signal after adding noise is recorded as x1(t);
Step A2: using least square support vector machine to x obtained in step A.11(t) continuation of the signal;
for x1(t) sampling to obtain a sampling sequence { x (1), x (2), x (3), ·, x (N) }, wherein N is the number of sampling points, and the training sample set is B { (h)1,g1),(h2,g2),···,(hl,gl)}。
Specifically, in this embodiment, the number of sampling points is 2000, the training sample is 100, and the training sample can be obtained as follows: the input samples are 100 × 1900 dimensional data.
The first predictor of continuation to the right is x (N + 1); then, x (N +1) is used as a new boundary point of the original data, and the 2 nd data sequence continuation value x (N +2) is obtained by the same method. By analogy, all continuation sequences x (N +1), x (N +2) …, x (N + M) can be obtained according to the number of data points required to be continued, and the forward continuation method for a given data sequence is the same as the backward continuation method.
100 sampling points are respectively extended from two end points of the signal to two sides, namely, an extended sequence with M being 100 is as follows: { x (1), x (2), x (3),. cndot., x (2200) }.
Step A3: constructing a signal envelope line by utilizing a conformal spline interpolation method;
specifically, in this embodiment, the magnitude relationship between each point in the sequence obtained in step a.2 and its adjacent points is compared to determine whether the point is an extreme point, and according to the comparison rule, the compared maximum sequence is { x }max(t0),xmax(t1),...,xmax(tb) B is the number of maximum points; inserting two values between two maximum values of the formula (2) as control vertexes of the T-B spline, and constructing an upper envelope of the signal by using the formula (3) and recording the upper envelope as the upper envelopeThe method of constructing the lower envelope is similar to that of the upper envelope, and is described
Step A4: calculating the mean value m of the upper and lower envelope curves using equation (6)a(t);
Step A5: calculating the signal x obtained in step A.2 using equation (7)1' (t) and mean value ma(t) the difference;
judging whether C (t) meets the IMF definition interception condition according to the formula (8), namely meeting the IMF definition interception conditionWhen ZSD is less than 0.3, extracting C (t) as IMF; otherwise using the formulaCalculating the residual quantity, making the residual quantity be an original signal, and repeating the steps A1-A5 until the screening is stopped when the residual component is a monotonic function.
Step A6: changing the weight factor omega of the step A.1, and carrying out screening of the step A.1 to the step A.5 for m times;
specifically, in this embodiment, the white noise amplitude may be 0.05 times, 0.06 times and 0.04 times of the standard deviation of the electrocardiographic signal, and the sum of the white noise amplitudes is 100 times;
step A7: all IMF components of the signal subjected to EMD can be obtained by using the formula (12);
and B: performing effective signal judgment on each obtained IMF through arranging mutual information;
step B1: solving the permutation entropy of the time series;
specifically to this embodiment, the embedding dimension is 1001 and the time delay is 1. Calculating time series IMF according to Shannon entropy of permutation probability density function(k)Permutation entropy S (IMF) of (t) and y (t)(k)) And S (y); calculating the joint time series (IMF) using equation (18)(k) (t), y (t) joint permutation entropy S (IMF)(k),y)。
Step B2: calculating permutation mutual information by using a formula (13);
step B3: and judging the degree of noise interference of each IMF according to the QI value of the mutual information of each IMF and the original signal, wherein the more the noise quantity is, the smaller the QI value is. And selecting the IMF with a small obvious QI value for denoising.
And C: b, performing threshold denoising treatment on the IMF which is selected in the step B and needs to be denoised;
specifically, in this embodiment, the selected IMF is subjected to denoising processing using equation (23).
Step D: and C, performing signal reconstruction on the IMF remained in the step B and the signal processed in the step C.
The signal is reconstructed by equation (24).
Therefore, the electrocardiosignal denoising method based on the fusion of the improved EMD and the threshold method is completed from the step A to the step D.
Claims (10)
1. An electrocardiosignal denoising method based on the fusion of an improved EMD and a threshold method comprises the following steps:
A. performing an improved EMD decomposition of the acquired signal, in particular:
A1. adding omega to the collected signal y (t)aThe multiplied mean value is zero, and the positive coefficient white noise n (t) of unit variance is obtained to obtain a signalSubscript a indicates the a-th addition of white noise;
A2. signal pair using least squares support vector machineCarrying out continuation at two ends to obtain a continuation sequence;
A3. constructing the upper envelope of the continuation sequence by using a conformal spline interpolation methodAnd lower envelopej represents the j section of T-B spline fitting curve;
A4. calculating the mean value of the upper envelope line and the lower envelope line obtained after white noise is added for the a-th timeAnd a signalAnd maDifference of (t)If C (t) does not meet the IMF defined cutoff condition, repeating step A3; otherwiseExtracting C (t) asThe IMF of the ith EMD decomposition of the added positive coefficient white noise is shown; calculating the residual amount
A5. Taking the residual amount r (t) of the step a4 as a new signal, namely r (t) ═ y (t), and then screening through the steps a 1-a 4 to obtain the next IMF with lower frequency, and stopping screening until the screened IMF component meets ZSD < theta, wherein theta is a set threshold value, and the ZSD calculation formula is as follows:
IMFi(t) is the IMF of the ith EMD decomposition, and n is the IMFi(t) length;
A6. signals decomposed from A1 to A5 are shown asWherein d is the number of IMFs after EMD decomposition of the electrocardiosignals,adding IMF, r of positive coefficient white noise subjected to I EMD decomposition to the ad(t) is the residual error when the d-th decomposition is performed;
similar to the steps A1-A5, EMD decomposition is performed on the signal after negative coefficient white noise is added to the electrocardiosignal, and the decomposed signal is expressed asWherein,adding IMF of negative coefficient white noise decomposed by the ith EMD for the ith time;
A7. adding the white noise with the positive coefficient and the negative coefficient obtained in the step A6 and then performing IMF accumulation and averaging to obtainWherein,
B. judging the linear relation between each IMF and the original signal through the permutation mutual information, and judging the effective signal of the IMF obtained in the step A;
C. b, performing threshold denoising treatment on the IMF which is selected in the step B and needs to be denoised;
D. and C, performing signal reconstruction on the IMF remained in the step B and the signal processed in the step C.
2. The method for denoising an electrocardiographic signal according to claim 1, wherein a2 includes: to pairSampling is carried out to obtain a sampling sequence ofN is the number of sampling points; the output of the least squares support vector machine isWherein,is the first signal after continuation; then will beObtaining the 2 nd data sequence continuation value as a new boundary point of the original dataBy analogy, all continuation sequences are obtained according to the number of data points needing to be prolonged Wherein M is the number of signal points extended to the right; left continuation for a given data sequenceThe final continuation sequence is
3. The method for denoising an electrocardiographic signal according to claim 1 or 2, wherein a3 comprises: comparing the magnitude relation between a certain point in the continuation sequence and the left and right adjacent points to judge whether the point is an extreme point; constructing an upper envelope by means of maximum pointsConstructing the lower envelope by minimum points
4. The method for denoising an electrocardiographic signal according to claim 3, wherein the method for judging whether the point is an extreme point comprises: for end pointsAndif it isThen point is reachedIs the maximum point, otherwise, the pointIs a minimum value point; if it isThen point is reachedIs the maximum point, otherwise, the pointIs a minimum value point;
5. The method for denoising an electrocardiographic signal according to claim 1, wherein the step B comprises:
B1. computing time series IMF(k)Permutation entropy S (IMF) of (t) and y (t)(k)) And S (y);
B2. calculating arrangement mutual information;
B3. and judging the degree of noise interference of each IMF according to the mutual information QI value of each IMF and the original signal, and selecting the IMF with the small QI value for denoising.
6. The electrocardiosignal denoising method of claim 1 or 5, wherein the calculation formula of the arrangement mutual information is:
QI(IMF(k),y)=S(IMF(k))+S(y)-S(IMF(k)y) where S (IMF)(k)) And S (y) are respectively IMF(k)(t) and y (t) entropy of alignment, S (IMF)(k)Y) is IMF(k)(t) and y (t) joint permutation entropy.
8. The method of denoising an electrocardiographic signal of claim 6, wherein the IMF is(k)Joint permutation entropy S (IMF) of (t) and y (t)(k)Y) is calculated asWherein, is arranged (pi)i,πj) Representation of IMF(k)(t) and y (t) a permutation order corresponding to each state vector after the time series is mapped to the d-dimensional space, and the probability density is combinedThe subscripts i ═ 1,2, ·, n- (d-1) τ,is a pair of state space trajectory matrices, which correspond to an arrangement of (pi)i,πj)。
9. The method for denoising an electrocardiographic signal according to claim 1, wherein the threshold value in step C is calculated by:
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