CN110664719A - Skin care product with wrinkle removing and anti-aging effects and preparation method thereof - Google Patents

Skin care product with wrinkle removing and anti-aging effects and preparation method thereof Download PDF

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Publication number
CN110664719A
CN110664719A CN201910999481.4A CN201910999481A CN110664719A CN 110664719 A CN110664719 A CN 110664719A CN 201910999481 A CN201910999481 A CN 201910999481A CN 110664719 A CN110664719 A CN 110664719A
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honey
fermentation
care product
skin care
wine
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Chinese (zh)
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许驰名
朱海亮
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Nanjing Divio Pharmaceutical Technology Co Ltd
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Nanjing Divio Pharmaceutical Technology Co Ltd
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Priority to CN201910999481.4A priority Critical patent/CN110664719A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Zoology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to a skin care product with wrinkle removing and anti-aging effects and a preparation method thereof, wherein the skin care product comprises the following components in percentage by mass: 70-80% of honey wine, 2-16% of acetyl hexapeptide-8 and 1-5% of aloe extract; the honey wine is prepared by a fermentation process, acetyl hexapeptide-8 and aloe extract are added into the honey wine, and the effects of the acetyl hexapeptide-8 and the aloe extract are cooperated, so that the honey wine can moisten skin and reduce water loss, can promote the synthesis of collagen, can moisturize and repair damaged skin, can improve skin elasticity, and can improve skin in various aspects to achieve the effects of resisting wrinkles and resisting aging.

Description

Skin care product with wrinkle removing and anti-aging effects and preparation method thereof
Technical Field
The invention relates to a skin care product with wrinkle removing and anti-aging effects and a preparation method thereof.
Background
Along with the increase of age, the organism begins to age gradually, and human metabolism begins to slow down, and moisture and subcutaneous fat reduce, and collagen runs off gradually, and especially face skin corium layer collagen runs off, and the elasticity loss problem is especially serious, and in order to prolong skin life-span resistance age-related, skin is urgently needed to be saved. Along with the change of life style of people, the beauty of skin is more and more emphasized, and the generation of wrinkles, especially the generation of facial skin wrinkles, becomes the most annoying problem for people. However, most of the currently adopted cosmetics have the problems of unclear effect and certain adverse reaction, and people very need products with the effects of wrinkle resistance and anti-aging, which have clear effect, various action ways, safety and no adverse reaction.
Disclosure of Invention
Aiming at the defects of the prior art, the invention solves the problems that: provides a skin care product with no side effect and adverse reaction and good wrinkle removing and anti-aging effects and a preparation method thereof.
In order to solve the problems, the technical scheme adopted by the invention is as follows:
a skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following components in percentage by mass: 70-80% of honey wine, 2-16% of acetyl hexapeptide-8 and 1-5% of aloe extract.
Further, the raw materials of the honey wine comprise honey and purified water; the weight ratio of the honey to the purified water is 1: 3-1: 8; the sugar content of the honey wine is 10-16%.
Further, the alcoholic strength of the honey wine is 5-8 degrees.
A preparation method of a skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following steps:
1. the preparation method of the honey wine comprises the following steps:
1) preparing materials: selecting honey for later use;
2) diluting honey: diluting honey and purified water, and adjusting sugar degree to make the sugar content of the diluted honey 10-16% to obtain honey juice;
3) and (3) pasteurization: placing the honey juice at 70-90 ℃ for 28-32 minutes, and sterilizing;
4) adding SO2: adding SO into the sterilized honey juice2So as to inhibit the growth of mixed bacteria and prevent the destruction of the microbial mixed bacteria to the nutrient components in the raw materials and the generation of mixed taste;
5) pre-fermentation: inoculating yeast into the honey juice, and fermenting for 10-15 days at the temperature of 20-28 ℃;
6) and (3) after-fermentation:after the primary fermentation is finished, filtering the fermentation liquor and pouring the fermentation liquor, and simultaneously adding SO into the fermentation liquor2Adjusting the fermentation temperature to continue fermentation;
7) and (3) filtering and sterilizing: and filtering and sterilizing after the post-fermentation is finished to obtain the honey wine.
2. Adding the ingredients: mixing 70-80% of bee wine, 2-16% of acetyl hexapeptide-8 and 1-5% of aloe extract according to the weight ratio, adjusting the temperature, stirring, homogenizing in a homogenizer, and standing to obtain the finished product.
Further, in the material preparation step in the step 1, honey with a water content of 10% -20% and a sugar content of 70% -80% is selected for standby.
Further, in the step of diluting honey in the step 1, the honey and the purified water are diluted according to the weight ratio of 1: 3-1: 8.
Further, adding SO in the step 12In the step, 40 mg/L-80 mg/L SO is added into the sterilized honey juice2
Furthermore, in the post-fermentation step in the step 1, 40mg/L ~ 60mg/L SO 60mg/L is added into the fermentation liquor2And adjusting the fermentation temperature to 4-8 ℃, and continuing to ferment for 10-20 days.
Further, in the step 2, stirring for 20-40 minutes at 25-32 ℃, then homogenizing for 60-90 minutes in a homogenizer, and standing for 5-6 hours.
The invention has the advantages of
1. According to the invention, the honey wine is prepared by a fermentation process, acetyl hexapeptide-8 and aloe extract are added, and the effects of the acetyl hexapeptide-8 and the aloe extract are cooperated, so that the skin can be moistened and the water loss is reduced, the synthesis of collagen can be promoted, the skin can be moisturized and damaged skin can be repaired, the skin elasticity can be improved, and the effects of resisting wrinkles and resisting aging can be achieved by improving the skin in various aspects.
2. The honey has very high nutritive value, contains rich nutrient substances required by human bodies, and is particularly beneficial to the health of the skin of the human bodies. The honey is a skin cell breeding agent, can increase the activity of epidermal cells when being externally used, improves the nutrition condition of the skin, thereby keeping the skin natural ruddy and white and tender, eliminating and reducing wrinkles and having the special efficacy of preventing skin aging. Acetyl hexapeptide-8 is a high-quality wrinkle-removing raw material, has high wrinkle-removing activity and small side effect, can locally block nerve transmission muscle contraction information, influences the nerve conduction of a skin sac, relaxes facial muscles and achieves the aim of smoothing dynamic lines, static lines and fine lines; effectively reorganizes the elasticity of collagen, can increase the activity of elastin, relaxes the lines of the face, and smoothes wrinkles and improves laxity. It can be used as anti-wrinkle component with excellent effect.
Detailed Description
The present invention will be described in further detail below.
Example 1
A skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following components in percentage by mass: 70% of honey wine, 2% of acetyl hexapeptide-8 and 1% of aloe extract. Further, the raw materials of the honey wine comprise honey and purified water; the weight ratio of the honey to the purified water is 1: 3; the honey wine contains 10% of sugar. Further, the alcohol content of the honey wine is 5 degrees.
A preparation method of a skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following steps:
1. the preparation method of the honey wine comprises the following steps:
1) preparing materials: selecting honey for later use; selecting honey with water content of 10% and sugar content of 70% for use.
2) Diluting honey: diluting Mel and purified water, adjusting sugar degree to make the sugar content of diluted Mel be 10%, and making into Mel juice; diluting honey and purified water at a weight ratio of 1: 3.
3) And (3) pasteurization: keeping the honey juice at 70 deg.C for 28 min, and sterilizing;
4) adding SO2: adding SO into the sterilized honey juice2To inhibit the growth of mixed bacteria and prevent the microbial mixed bacteria pairDestruction of nutrient components in the raw materials and generation of foreign flavor; adding 40mg/L SO into the sterilized Mel juice2
5) Pre-fermentation: inoculating yeast into the honey juice, and fermenting at 20 deg.C for 10 days;
6) and (3) after-fermentation: after the primary fermentation is finished, filtering the fermentation liquor and pouring the fermentation liquor, and simultaneously adding SO into the fermentation liquor2Adjusting the fermentation temperature to continue fermentation; adding 40mg/L SO into the fermentation liquor2And adjusting the fermentation temperature to 4 ℃, and continuing the fermentation for 10 days.
7) And (3) filtering and sterilizing: and filtering and sterilizing after the post-fermentation is finished to obtain the honey wine.
2. Adding the ingredients: mixing 70% of bee wine, 2% of acetyl hexapeptide-8 and 1% of aloe extract according to weight ratio, adjusting temperature, stirring, homogenizing in a homogenizer, and standing to obtain the final product; stirring at 25 deg.C for 20 min, homogenizing in homogenizer for 60 min, and standing for 5 hr.
Example 2
A skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following components in percentage by mass: 75% of honey wine, 5% of acetyl hexapeptide-8 and 2% of aloe extract. Further, the raw materials of the honey wine comprise honey and purified water; the weight ratio of the honey to the purified water is 1: 5; the honey wine contains 12% of sugar. Further, the alcohol content of the honey wine is 6 degrees.
A preparation method of a skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following steps:
1. the preparation method of the honey wine comprises the following steps:
1) preparing materials: selecting honey for later use; selecting honey with water content of 12% and sugar content of 73% for use.
2) Diluting honey: diluting Mel and purified water, adjusting sugar degree to make the sugar content of diluted Mel 12%, and making into Mel juice; diluting honey and purified water at a weight ratio of 1: 5.
3) And (3) pasteurization: keeping the honey juice at 72 deg.C for 29 min, and sterilizing;
4) adding SO2: adding SO into the sterilized honey juice2So as to inhibit the growth of mixed bacteria and prevent the destruction of the microbial mixed bacteria to the nutrient components in the raw materials and the generation of mixed taste; adding 50mg/L SO into the sterilized honey juice2
5) Pre-fermentation: inoculating yeast into the honey juice, and fermenting at 22 deg.C for 12 days;
6) and (3) after-fermentation: after the primary fermentation is finished, filtering the fermentation liquor and pouring the fermentation liquor, and simultaneously adding SO into the fermentation liquor2Adjusting the fermentation temperature to continue fermentation; adding 43/L SO to the fermentation broth2And adjusting the fermentation temperature to 5 ℃, and continuing to ferment for 13 d.
7) And (3) filtering and sterilizing: and filtering and sterilizing after the post-fermentation is finished to obtain the honey wine.
2. Adding the ingredients: mixing bee wine, acetyl hexapeptide-8 and aloe extract at a certain weight ratio, regulating temperature, stirring, homogenizing in a homogenizer, and standing to obtain the final product; stirred at 27 ℃ for 22 minutes, then homogenized in a homogenizer for 65 minutes and left for 5.2 hours.
Example 3
A skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following components in percentage by mass: 76% of honey wine, 10% of acetyl hexapeptide-8 and 3% of aloe extract. Further, the raw materials of the honey wine comprise honey and purified water; the weight ratio of the honey to the purified water is 1: 5; the honey wine contains 14% of sugar. Further, the alcohol content of the honey wine is 7 degrees.
A preparation method of a skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following steps:
1. the preparation method of the honey wine comprises the following steps:
1) preparing materials: selecting honey for later use; selecting honey with water content of 15% and sugar content of 75% for use.
2) Diluting honey: diluting Mel and purified water, adjusting sugar degree to make the sugar content of diluted Mel be 14%, and making into Mel juice; diluting honey and purified water at a weight ratio of 1: 5.
3) And (3) pasteurization: keeping the honey juice at 80 deg.C for 30 min, and sterilizing;
4) adding SO2: adding SO into the sterilized honey juice2So as to inhibit the growth of mixed bacteria and prevent the destruction of the microbial mixed bacteria to the nutrient components in the raw materials and the generation of mixed taste; adding 70mg/L SO into the sterilized Mel juice2
5) Pre-fermentation: inoculating yeast into the honey juice, and fermenting at 27 deg.C for 13 days;
6) and (3) after-fermentation: after the primary fermentation is finished, filtering the fermentation liquor and pouring the fermentation liquor, and simultaneously adding SO into the fermentation liquor2Adjusting the fermentation temperature to continue fermentation; adding 50mg/L SO into the fermentation liquor2And adjusting the fermentation temperature to 6 ℃, and continuing to ferment for 17 d.
7) And (3) filtering and sterilizing: and filtering and sterilizing after the post-fermentation is finished to obtain the honey wine.
2. Adding the ingredients: mixing bee wine, acetyl hexapeptide-8 and aloe extract at a certain weight ratio, regulating temperature, stirring, homogenizing in a homogenizer, and standing to obtain the final product; stirring at 28 deg.C for 32 min, homogenizing in homogenizer for 80 min, and standing for 5.5 hr.
Example 4
A skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following components in percentage by mass: the honey wine is 78%, the acetyl hexapeptide-8 is 15%, and the aloe extract is 4%. Further, the raw materials of the honey wine comprise honey and purified water; the weight ratio of the honey to the purified water is 1: 7; the honey wine contains 15% of sugar. Further, the alcohol content of the honey wine is 7 degrees.
A preparation method of a skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following steps:
1. the preparation method of the honey wine comprises the following steps:
1) preparing materials: selecting honey for later use; selecting Mel with water content of 18% and sugar content of 780% for use.
2) Diluting honey: diluting Mel and purified water, adjusting sugar degree to make the sugar content of diluted Mel be 15%, and making into Mel juice; diluting honey and purified water at a weight ratio of 1: 7.
3) And (3) pasteurization: keeping the honey juice at 88 deg.C for 31 min, and sterilizing;
4) adding SO2: adding SO into the sterilized honey juice2So as to inhibit the growth of mixed bacteria and prevent the destruction of the microbial mixed bacteria to the nutrient components in the raw materials and the generation of mixed taste; adding 75mg/L SO into the sterilized Mel juice2
5) Pre-fermentation: inoculating yeast into the honey juice, and fermenting at 27 deg.C for 14 days;
6) and (3) after-fermentation: after the primary fermentation is finished, filtering the fermentation liquor and pouring the fermentation liquor, and simultaneously adding SO into the fermentation liquor2Adjusting the fermentation temperature to continue fermentation; adding 56mg/L SO into the fermentation liquor2And adjusting the fermentation temperature to 7 ℃, and continuing the fermentation for 18 d.
7) And (3) filtering and sterilizing: and filtering and sterilizing after the post-fermentation is finished to obtain the honey wine.
2. Adding the ingredients: mixing bee wine, acetyl hexapeptide-8 and aloe extract at a certain weight ratio, regulating temperature, stirring, homogenizing in a homogenizer, and standing to obtain the final product; stirring at 31 deg.C for 38 min, homogenizing in homogenizer for 88 min, and standing for 5.8 hr.
Example 5
A skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following components in percentage by mass: the honey wine is 80%, the acetyl hexapeptide-8 is 16%, and the aloe extract is 5%. Further, the raw materials of the honey wine comprise honey and purified water; the weight ratio of the honey to the purified water is 1: 8; the honey wine contains 16% of sugar. Further, the alcohol content of the honey wine is 8 degrees.
A preparation method of a skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following steps:
1. the preparation method of the honey wine comprises the following steps:
1) preparing materials: selecting honey for later use; selecting honey with water content of 20% and sugar content of 80% for use.
2) Diluting honey: diluting Mel and purified water, adjusting sugar degree to make the sugar content of diluted Mel 16%, and making into Mel juice; diluting honey and purified water at a weight ratio of 1: 8.
3) And (3) pasteurization: keeping the honey juice at 90 deg.C for 32 min, and sterilizing;
4) adding SO2: adding SO into the sterilized honey juice2So as to inhibit the growth of mixed bacteria and prevent the destruction of the microbial mixed bacteria to the nutrient components in the raw materials and the generation of mixed taste; adding 80mg/L SO into the sterilized Mel juice2
5) Pre-fermentation: inoculating yeast into the honey juice, and fermenting at 28 deg.C for 15 days;
6) and (3) after-fermentation: after the primary fermentation is finished, filtering the fermentation liquor and pouring the fermentation liquor, and simultaneously adding SO into the fermentation liquor2Adjusting the fermentation temperature to continue fermentation; adding 60mg/L SO into fermentation liquor2And adjusting the fermentation temperature to 8 ℃, and continuing to ferment for 20 days.
7) And (3) filtering and sterilizing: and filtering and sterilizing after the post-fermentation is finished to obtain the honey wine.
2. Adding the ingredients: mixing bee wine, acetyl hexapeptide-8 and aloe extract at a certain weight ratio, regulating temperature, stirring, homogenizing in a homogenizer, and standing to obtain the final product; stirring at 32 deg.C for 40 min, homogenizing in homogenizer for 90 min, and standing for 6 hr.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (9)

1. A skin care product with wrinkle removing and anti-aging effects is characterized by comprising the following components in percentage by mass: 70-80% of honey wine, 2-16% of acetyl hexapeptide-8 and 1-5% of aloe extract.
2. The skin care product with the wrinkle-removing and anti-aging effects as claimed in claim 1, wherein the raw materials of the mead comprise honey and purified water; the weight ratio of the honey to the purified water is 1: 3-1: 8; the sugar content of the honey wine is 10-16%.
3. The skin care product with the wrinkle-removing and anti-aging effects as claimed in claim 1, wherein the alcohol content of the honey wine is 5-8 degrees.
4. A method for preparing the skin care product with the functions of removing wrinkles and resisting senility as claimed in claim 1, which is characterized by comprising the following steps:
1. the preparation method of the honey wine comprises the following steps:
1) preparing materials: selecting honey for later use;
2) diluting honey: diluting honey and purified water, and adjusting sugar degree to make the sugar content of the diluted honey 10-16% to obtain honey juice;
3) and (3) pasteurization: placing the honey juice at 70-90 ℃ for 28-32 minutes, and sterilizing;
4) adding SO2: adding SO into the sterilized honey juice2So as to inhibit the growth of mixed bacteria and prevent the destruction of the microbial mixed bacteria to the nutrient components in the raw materials and the generation of mixed taste;
5) pre-fermentation: inoculating yeast into the honey juice, and fermenting for 10-15 days at the temperature of 20-28 ℃;
6) and (3) after-fermentation: after the primary fermentation is finished, filtering the fermentation liquor and pouring the fermentation liquor, and simultaneously adding SO into the fermentation liquor2Adjusting the fermentation temperature to continue fermentation;
7) and (3) filtering and sterilizing: filtering and sterilizing after the post-fermentation to obtain the honey wine;
2. adding the ingredients: mixing 70-80% of bee wine, 2-16% of acetyl hexapeptide-8 and 1-5% of aloe extract according to the weight ratio, adjusting the temperature, stirring, homogenizing in a homogenizer, and standing to obtain the finished product.
5. The method for preparing a skin care product with wrinkle removing and antiaging effects as claimed in claim 4, wherein in the material preparation step in step 1, honey with water content of 10% -20% and sugar content of 70% -80% is selected for use.
6. The method for preparing the skin care product with the wrinkle-removing and anti-aging effects according to claim 4, wherein in the step of diluting honey in the step 1, the honey and purified water are diluted according to the weight ratio of 1: 3-1: 8.
7. The method for preparing skin care product with wrinkle removing and antiaging effects as claimed in claim 4, wherein SO is added in step 12In the step, 40 mg/L-80 mg/L SO is added into the sterilized honey juice2
8. The method for preparing skin care product with wrinkle removing and antiaging effects as claimed in claim 4, wherein the post-fermentation step in step 1 comprises adding SO 40mg/L ~ 60mg/L into the fermentation broth2And adjusting the fermentation temperature to 4-8 ℃, and continuing to ferment for 10-20 days.
9. The method for preparing a skin care product with the effects of removing wrinkles and resisting aging according to claim 4, wherein in the step 2, the mixture is stirred for 20-40 minutes at the temperature of 25-32 ℃, and then is homogenized for 60-90 minutes in a homogenizer and is kept still for 5-6 hours.
CN201910999481.4A 2019-10-21 2019-10-21 Skin care product with wrinkle removing and anti-aging effects and preparation method thereof Pending CN110664719A (en)

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CN105441270A (en) * 2016-01-12 2016-03-30 成都牧蜂人蜂产品有限公司 Honey mead brewed by red kojic rice, distilled liquor and preparation method of honey mead
CN107308059A (en) * 2017-07-31 2017-11-03 广东芭薇生物科技股份有限公司 The lifting elite dew that compacts of the wine containing ice
EP3375434A1 (en) * 2008-10-13 2018-09-19 Lipotec, S.A. Cosmetic or dermopharmaceutical composition containing pseudoalteromonas ferment extract
CN108676664A (en) * 2018-06-29 2018-10-19 桐梓县德毓蜂业发展有限公司 A kind of preparation method of hydromel

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Publication number Priority date Publication date Assignee Title
EP3375434A1 (en) * 2008-10-13 2018-09-19 Lipotec, S.A. Cosmetic or dermopharmaceutical composition containing pseudoalteromonas ferment extract
CN105168106A (en) * 2015-08-14 2015-12-23 北京兰厚化妆品有限责任公司 Three-flower whitening and skin tendering facial mask liquid and preparation method therefor
CN105441270A (en) * 2016-01-12 2016-03-30 成都牧蜂人蜂产品有限公司 Honey mead brewed by red kojic rice, distilled liquor and preparation method of honey mead
CN107308059A (en) * 2017-07-31 2017-11-03 广东芭薇生物科技股份有限公司 The lifting elite dew that compacts of the wine containing ice
CN108676664A (en) * 2018-06-29 2018-10-19 桐梓县德毓蜂业发展有限公司 A kind of preparation method of hydromel

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Application publication date: 20200110