CN110654683A - Cabinet is stored to aseptic article - Google Patents

Cabinet is stored to aseptic article Download PDF

Info

Publication number
CN110654683A
CN110654683A CN201910899008.9A CN201910899008A CN110654683A CN 110654683 A CN110654683 A CN 110654683A CN 201910899008 A CN201910899008 A CN 201910899008A CN 110654683 A CN110654683 A CN 110654683A
Authority
CN
China
Prior art keywords
cabinet body
transition
storage cabinet
cavity
unit placing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910899008.9A
Other languages
Chinese (zh)
Inventor
王娟
于利萍
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Peking Union Medical College Hospital Chinese Academy of Medical Sciences
Original Assignee
Peking Union Medical College Hospital Chinese Academy of Medical Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peking Union Medical College Hospital Chinese Academy of Medical Sciences filed Critical Peking Union Medical College Hospital Chinese Academy of Medical Sciences
Priority to CN201910899008.9A priority Critical patent/CN110654683A/en
Publication of CN110654683A publication Critical patent/CN110654683A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • A61L2/10Ultra-violet radiation

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

The invention relates to the field of medical treatment, in particular to an aseptic article storage cabinet, which comprises a front cabinet body and a rear cabinet body, wherein the front cabinet body is provided with a transition cavity, the rear cabinet body is provided with unit placing cavities, the number of the transition cavities is three, the unit placing cavities are arranged on the front cabinet body at equal intervals, the rear cabinet body is provided with three transverse lines and three rows corresponding to the transition cavities, and the inner end heads of the unit placing cavities are provided with pushing assemblies; an automatic recovery door is arranged between the unit placing cavity and the transition cavity; an ultraviolet lamp is installed inside the transition cavity. Realized aseptic article and fallen into inside the transition chamber after the extrusion is opened automatic recovery door, automatic recovery door self-closing keeps apart the leakproofness good, and then can not pollute the aseptic article of the same kind to and realized independent storing and ejection of compact alone, and then can not cross contamination aseptic article of other types, the unit is placed the chamber and is set up for being with the level with the transition chamber, is different from traditional vending machine goods and falls out the formula ejection of compact, the fragile problem.

Description

Cabinet is stored to aseptic article
Technical Field
The invention relates to the field of medical treatment, in particular to a sterile article storage cabinet.
Background
Sterile means no viable bacteria, and is an important concept in biotechnology. Only under the precondition that the culture medium, the fermentation equipment and the like are aseptic, pure culture can be realized after the microorganism inoculation, and the required product is finally obtained. Methods for preventing microorganisms from entering the body or object are known as aseptic procedures or aseptic techniques. The aseptic operation regulations are strictly observed when microbiological experiments, surgical operations, dressing change and injections are performed.
The aseptic article storage cabinet that uses in traditional hospital is simple iron sheet cabinet, and sealed isolation bacterium is poor, wholly only sets up two doors, and the aseptic article of different grade type are stacked together, stores that the cabinet is whole can expose in the outside and can pollute the aseptic article of the same kind of storing inside and the aseptic article of other types of cross contamination when getting aseptic article.
In order to solve the problems, the sterile article storage cabinet is particularly provided.
Disclosure of Invention
The present invention is directed to a storage cabinet for storing articles without bacteria, so as to solve the above problems.
In order to achieve the purpose, the invention provides the following technical scheme:
a storage cabinet for aseptic articles comprises a front cabinet body provided with a transition cavity and a rear cabinet body provided with a unit placing cavity, wherein the front cabinet body and the rear cabinet body are fixed integrally,
the traditional sterile article storage cabinet used in hospitals is a simple iron sheet cabinet, bacteria are sealed and isolated, only two doors are arranged on the whole cabinet, sterile articles of different types are stacked together, the storage cabinet can be exposed outside to pollute the like sterile articles stored in the storage cabinet and cross-pollute other types of sterile articles when the sterile articles are taken, furthermore, three transition cavities are arranged on the front cabinet body at equal intervals, three transverse three rows are arranged on the rear cabinet body corresponding to the transition cavities, and pushing assemblies are arranged on the inner end heads of the unit placing cavities;
meanwhile, an automatic recovery door is arranged between the unit placing cavity and the transition cavity;
an ultraviolet lamp is arranged in the transition cavity;
three outer protective doors which are distributed at equal intervals are arranged on the front cabinet body in a matched transition cavity.
Realized pushing away the material subassembly and will neatly arrange the aseptic article extrusion release of intracavity portion in the unit, aseptic article fall into the transition intracavity portion behind the extrusion is opened the automatic recovery door, automatic recovery door self-closing, open outer guard gate again and get the aseptic article of transition intracavity portion, get the back, it sterilizes to open the ultraviolet lamp to the inside of transition intracavity portion, it is good to keep apart the leakproofness, and then can not pollute the aseptic article of the same kind, the transition chamber is provided with threely, the unit is placed the chamber and is corresponded the transition chamber and be provided with three horizontal three rows, and then realized independent storing and ejection of compact alone, and then can not cross contamination aseptic article of other types, the unit is placed chamber and transition chamber and is the setting up for the same level, it falls the formula ejection of compact to be distinguished from traditional vending machine goods, fragile.
The further scheme of the invention is as follows: the pushing assembly is provided with an air cylinder, the front end of the air cylinder is fixedly provided with a push plate, the push plate is arranged in the unit placing cavity, the lower end of the push plate is fixedly provided with a pulley, and the cross section of the push plate is in a right trapezoid shape with a large upper part and a small lower part.
The invention further comprises the following scheme: and a protective box is arranged outside the cylinder.
The invention further comprises the following scheme: the automatic recovery door is provided with a fixed plate, the cross section of the fixed plate is U-shaped, the lower end of the fixed plate is rotatably fixed with a separation plate, the inner surface of the separation plate is connected with a spring, and the other end of the spring is connected inside the unit placing cavity.
The invention further comprises the following scheme: the spring is connected at one fifth of the position of the isolation plate from top to bottom.
The invention further comprises the following scheme: an inner pad is arranged on the inner surface of the isolation plate.
The invention further comprises the following scheme: the outer protective door is hinged to the front cabinet body through a hinge chain, a handle and a coded lock are installed on the outer protective door, and digital keys are arranged on the front cabinet body on the right side of the outer protective door.
The invention further comprises the following scheme: the lower end of the front cabinet body is fixed on the base, and four supporting legs distributed in a rectangular array are fixed at the lower end of the base.
The invention further comprises the following scheme: the display screen is installed to digit button upside, and control panel is installed to digit button downside.
Compared with the prior art, the invention has the beneficial effects that:
the automatic material-pushing machine has the advantages that the material-pushing assembly extrudes and pushes out sterile articles which are orderly arranged in the unit placing cavity, the sterile articles fall into the transition cavity after the automatic recovery door is extruded and opened, the automatic recovery door is automatically closed, the outer protection door is opened to take the sterile articles in the transition cavity, after the sterile articles are taken, the ultraviolet lamp is started to sterilize the interior of the transition cavity, the isolation and sealing performance is good, the like sterile articles cannot be polluted, the number of the transition cavities is three, three transverse three rows are arranged in the unit placing cavity corresponding to the transition cavity, the independent storage and independent discharge are realized, the sterile articles of other types cannot be cross-polluted, the unit placing cavity and the transition cavity are arranged in the same level, and the automatic material-pushing machine is different from the problems that the products fall, the discharge is easy to.
Drawings
Fig. 1 is a schematic front view of the storage cabinet for aseptic articles according to the present invention.
Fig. 2 is a schematic structural view of the aseptic storage cabinet of the present invention with the outer protective door removed.
Fig. 3 is a schematic structural view of the rear cabinet body in the aseptic article storage cabinet of the present invention.
Fig. 4 is a schematic cross-sectional view of the front and rear cabinets of the aseptic storage cabinet of the present invention.
FIG. 5 is a schematic structural diagram of the push plate in FIG. 4.
Fig. 6 is a schematic structural view of the automatic recovery door of fig. 4.
In the figure: 1-an outer protective door; 2-an articulated chain; 3-a base; 4-supporting legs; 5-a control panel; 6-number keys; 7-a display screen; 8-a handle; 9-a transition cavity; 10-a front cabinet body; 11-a rear cabinet body; 12-unit placement chambers; 13-push plate; 14-a cylinder; 15-a protective box; 16-an automatic recovery door; 91-ultraviolet lamp; 131-a pulley; 161-fixed plate; 162-a separator plate; 163-spring.
Detailed Description
The technical solution of the present invention will be described in further detail with reference to specific embodiments.
Example 1
In this embodiment, in order to prevent other sterile articles from being contaminated when taking the sterile articles, a storage cabinet for sterile articles is provided, specifically as shown in fig. 1 to 3, the storage cabinet includes a front cabinet body 10 having a transition cavity 9 and a rear cabinet body 11 having a unit placing cavity 12, where the front cabinet body 10 and the rear cabinet body 11 are integrally fixed.
The traditional sterile article storage cabinet used in hospitals is a simple iron sheet cabinet, bacteria are sealed and isolated, only two doors are arranged on the whole, sterile articles of different types are stacked together, when the sterile articles are taken, the whole storage cabinet can be exposed outside and can pollute the like sterile articles stored in the storage cabinet and cross-pollute other types of sterile articles, furthermore, three transition cavities 9 are arranged on the front cabinet body 10 at equal intervals, three transverse three rows are arranged on the rear cabinet body 11 corresponding to the transition cavities 9 in the unit placing cavities 12, and pushing assemblies are arranged at the inner ends of the unit placing cavities 12; meanwhile, an automatic recovery door 16 is arranged between the unit placing cavity 12 and the transition cavity 9; the transition chamber 9 is internally provided with an ultraviolet lamp 91 (the wavelength of the ultraviolet lamp 91 is within 253.7nm-185 nm), which can be referred to fig. 3.
Meanwhile, three outer protective doors 1 distributed at equal intervals are arranged on the front cabinet body 10 in a matched manner with the transition cavity 9.
Realized pushing away the material subassembly and will neatly arrange and place the aseptic article extrusion release of intracavity portion 12 in the unit, aseptic article fall into the inner part of transition chamber 9 behind extrusion division automatic recovery door 16, automatic recovery door 16 self-closing, open outer guard gate 1 again and get the aseptic article of inner part of transition chamber 9, get the back, open ultraviolet lamp 91 and disinfect to the inner part of transition chamber 9, it is good to keep apart the leakproofness, and then can not pollute the aseptic article of the same kind, transition chamber 9 is provided with threely, the unit is placed chamber 12 and is corresponded transition chamber 9 and be provided with three horizontal three rows, and then realized independent storing and independent ejection of compact, and then can not cross contamination aseptic article of other types, the unit is placed chamber 12 and transition chamber 9 and is the same level setting, be different from the falling type ejection of compact of traditional automatic machine goods, fragile problem is sold.
Example 2
The embodiment of the invention provides a sterile article storage cabinet, which is further defined on the basis of the embodiment 1.
As shown in fig. 4 and 5, the pushing assembly is provided with an air cylinder 14, a pushing plate 13 is fixed at the front end of the air cylinder 14, the pushing plate 13 is arranged inside the unit placing cavity 12, a pulley 131 is fixed at the lower end of the pushing plate 13, and the cross section of the pushing plate 13 is in a right-angled trapezoid shape with a large upper part and a small lower part.
Further, a protective box 15 is arranged outside the cylinder 14.
Example 3
The embodiment of the invention provides a sterile article storage cabinet, which is further defined on the basis of the embodiment 1 and the embodiment 2.
As shown in fig. 6, the automatic recovery door 16 is provided with a fixing plate 161, the fixing plate 161 has a U-shaped cross section, a partition plate 162 is rotatably fixed at the lower end of the fixing plate 161, a spring 163 is connected to the inner surface of the partition plate 162, the spring 163 is connected to one fifth of the partition plate 162 from top to bottom, and the other end of the spring 163 is connected to the inside of the unit placing chamber 12.
Further, an inner pad is disposed on an inner surface of the isolation plate 162.
Example 4
The embodiment of the invention provides a sterile article storage cabinet, which is further defined on the basis of the embodiments 1-3.
As shown in figure 1, the outer protective door 1 is hinged to the front cabinet body 10 through a hinge chain 2, a handle 8 and a coded lock are installed on the outer protective door 1, a digital key 6 is arranged on the front cabinet body 10 on the right side of the outer protective door 1, and an automatic timer is installed at the top of the outer protective door 1.
And the digital key 6 is matched with a coded lock for use to carry out safety switch.
Furthermore, the lower end of the front cabinet body 10 is fixed on the base 3, and four supporting legs 4 distributed in a rectangular array are fixed at the lower end of the base 3.
Furthermore, a display screen 7 is installed on the upper side of the number key 6, and a control panel 5 is installed on the lower side of the number key 6.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are used only for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention. Furthermore, the terms "first", "second", etc. are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first," "second," etc. may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless otherwise specified.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art through specific situations.
While the preferred embodiments of the present invention have been described in detail, the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art.

Claims (9)

1. A storage cabinet for aseptic articles is characterized in that the storage cabinet comprises a front cabinet body (10) provided with a transition cavity (9) and a rear cabinet body (11) provided with a unit placing cavity (12), the front cabinet body (10) and the rear cabinet body (11) are fixed in an integrated manner, wherein,
three transition cavities (9) are arranged on the front cabinet body (10) at equal intervals, three transverse three rows are arranged on the unit placing cavity (12) corresponding to the transition cavities (9) on the rear cabinet body (11), and a material pushing assembly is arranged on the inner end of the unit placing cavity (12);
an automatic recovery door (16) is arranged between the unit placing cavity (12) and the transition cavity (9); an ultraviolet lamp (91) is arranged in the transition cavity (9);
three outer protective doors (1) which are distributed at equal intervals are arranged on the front cabinet body (10) in a matched mode with the transition cavity (9).
2. The storage cabinet for the sterile articles according to claim 1, wherein the pushing assembly is provided with a cylinder (14), a push plate (13) is fixed at the front end of the cylinder (14), the push plate (13) is arranged inside the unit placing cavity (12), a pulley (131) is fixed at the lower end of the push plate (13), and the cross section of the push plate (13) is in a right trapezoid shape with a large upper part and a small lower part.
3. An aseptic storage cabinet according to claim 2, wherein a protective box (15) is provided outside said air cylinder (14).
4. The storage cabinet for sterile articles according to claim 1, wherein the automatic recovery door (16) is provided with a fixing plate (161), the cross section of the fixing plate (161) is U-shaped, the lower end of the fixing plate (161) is rotatably fixed with a separation plate (162), the inner surface of the separation plate (162) is connected with a spring (163), and the other end of the spring (163) is connected inside the unit placing cavity (12).
5. An aseptic storage cabinet as claimed in claim 4, wherein said spring (163) is connected to the partition (162) at a fifth from the top down.
6. The storage cabinet according to claim 4, wherein the inner surface of the partition (162) is provided with an inner pad.
7. The storage cabinet for sterile articles according to claim 1, wherein the outer protective door (1) is hinged on the front cabinet body (10) through a hinge chain (2), a handle (8) and a coded lock are installed on the outer protective door (1), and a digital key (6) is arranged on the front cabinet body (10) on the right side of the outer protective door (1).
8. The storage cabinet for sterile articles according to claim 7, wherein the lower end of the front cabinet body (10) is fixed on the base (3), and four support legs (4) are fixed on the lower end of the base (3) and distributed in a rectangular array.
9. The storage cabinet for sterile articles according to claim 7, wherein the upper side of the number button (6) is provided with a display screen (7), and the lower side of the number button (6) is provided with a control panel (5).
CN201910899008.9A 2019-09-23 2019-09-23 Cabinet is stored to aseptic article Pending CN110654683A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910899008.9A CN110654683A (en) 2019-09-23 2019-09-23 Cabinet is stored to aseptic article

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910899008.9A CN110654683A (en) 2019-09-23 2019-09-23 Cabinet is stored to aseptic article

Publications (1)

Publication Number Publication Date
CN110654683A true CN110654683A (en) 2020-01-07

Family

ID=69038855

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910899008.9A Pending CN110654683A (en) 2019-09-23 2019-09-23 Cabinet is stored to aseptic article

Country Status (1)

Country Link
CN (1) CN110654683A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111605868A (en) * 2020-06-19 2020-09-01 广州极飞科技有限公司 Automatic shipment distribution box, automatic shipment control method and unmanned equipment
CN112076049A (en) * 2020-10-18 2020-12-15 湖南丹菲医疗器械有限公司 Medical shallow of full automatic disinfection

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004058216A1 (en) * 2004-11-29 2006-06-01 Topik Didaktik Gmbh Storage arrangement especially for a pharmacy comprising a known design but also includes devices for storage and removal of articles in and from compartments
CN203425043U (en) * 2013-09-04 2014-02-12 张慧琳 Disposable sterile goods storage cabinet
CN206761144U (en) * 2016-12-14 2017-12-19 岑梓平 Combination sideboard with function of keeping secret
CN107518632A (en) * 2017-10-22 2017-12-29 王伟 A kind of medical drugses storage cabinet
CN109452779A (en) * 2018-11-09 2019-03-12 合肥全爱家居制造有限公司 A kind of domestic type intelligent bookshelf
CN209337404U (en) * 2018-12-07 2019-09-03 浙江织联网络科技股份有限公司 It is a kind of addition article to shopping cart system

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004058216A1 (en) * 2004-11-29 2006-06-01 Topik Didaktik Gmbh Storage arrangement especially for a pharmacy comprising a known design but also includes devices for storage and removal of articles in and from compartments
CN203425043U (en) * 2013-09-04 2014-02-12 张慧琳 Disposable sterile goods storage cabinet
CN206761144U (en) * 2016-12-14 2017-12-19 岑梓平 Combination sideboard with function of keeping secret
CN107518632A (en) * 2017-10-22 2017-12-29 王伟 A kind of medical drugses storage cabinet
CN109452779A (en) * 2018-11-09 2019-03-12 合肥全爱家居制造有限公司 A kind of domestic type intelligent bookshelf
CN209337404U (en) * 2018-12-07 2019-09-03 浙江织联网络科技股份有限公司 It is a kind of addition article to shopping cart system

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111605868A (en) * 2020-06-19 2020-09-01 广州极飞科技有限公司 Automatic shipment distribution box, automatic shipment control method and unmanned equipment
CN111605868B (en) * 2020-06-19 2023-12-26 广州极飞科技股份有限公司 Automatic shipment distribution box, automatic shipment control method and unmanned equipment
CN112076049A (en) * 2020-10-18 2020-12-15 湖南丹菲医疗器械有限公司 Medical shallow of full automatic disinfection

Similar Documents

Publication Publication Date Title
CN110654683A (en) Cabinet is stored to aseptic article
CN104875960A (en) Portable sterile pack storage box
CN113581617A (en) Case is deposited to portable medical treatment medicine
CN207524140U (en) A kind of medicine medicament storage rack put convenient for classification
CN210903834U (en) Hepatobiliary pancreas spleen surgery nursing car of changing dressings
CN212829942U (en) Device is provided in disinfection article storage
CN214357825U (en) Dampproofing antibiotic household articles for use containing box
CN214649907U (en) Medical kit
CN211459389U (en) Multi-purpose aseptic purification storage cabinet
CN217918740U (en) Quick sterilizing device of baby cabbage vacuum packaging equipment
CN217938729U (en) Dessert wrapping bag ultraviolet ray degassing unit
CN209797992U (en) Novel large capacity cell culture frame
CN219008525U (en) Emergency treatment box for test
CN214713261U (en) Cross infection prevention medical tray for critical care
CN213650352U (en) Medicine storage device
CN220193433U (en) Detachable medical treatment dish
CN214924313U (en) Medical storage rack
CN210698321U (en) Medical steam sterilizer beneficial to storing monitoring record list
CN215752534U (en) Sample transfer device for hospital
CN213554004U (en) Full-automatic ethylene oxide sterilizer
CN210785564U (en) Sterilization cabinet
CN214824908U (en) Medical sterilizer device
CN220938615U (en) Medical wrapping bag processing is with sterilization apparatus
CN219237071U (en) Tart skin turnover vehicle with ultraviolet sterilization function
CN214876632U (en) Clinical medicine student uses multi-functional medical kit

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20200107

RJ01 Rejection of invention patent application after publication