CN110651783A - Preparation method of pesticide liquid composition, pesticide liquid composition prepared based on preparation method and application of pesticide liquid composition - Google Patents

Preparation method of pesticide liquid composition, pesticide liquid composition prepared based on preparation method and application of pesticide liquid composition Download PDF

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Publication number
CN110651783A
CN110651783A CN201810691214.6A CN201810691214A CN110651783A CN 110651783 A CN110651783 A CN 110651783A CN 201810691214 A CN201810691214 A CN 201810691214A CN 110651783 A CN110651783 A CN 110651783A
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micro
preparation
fluid
mixing
liquid composition
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罗昌炎
詹姆斯.T.布里斯托
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Jiangsu Rotam Chemical Co Ltd
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Jiangsu Rotam Chemical Co Ltd
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds containing nitrogen-to-oxygen bonds
    • A01N33/18—Nitro compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
    • A01N35/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical at least one of the bonds to hetero atoms is to nitrogen
    • A01N35/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical at least one of the bonds to hetero atoms is to nitrogen containing a carbon-to-nitrogen double bond
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
    • A01N43/26—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings
    • A01N43/28—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N51/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds having the sequences of atoms O—N—S, X—O—S, N—N—S, O—N—N or O-halogen, regardless of the number of bonds each atom has and with no atom of these sequences forming part of a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing heterocyclic radicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/411—Emulsifying using electrical or magnetic fields, heat or vibrations
    • B01F23/4111—Emulsifying using electrical or magnetic fields, heat or vibrations using vibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/04—Mixing biocidal, pesticidal or herbicidal ingredients used in agriculture or horticulture, e.g. for spraying

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Toxicology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention relates to a preparation method of a pesticide liquid composition, the pesticide liquid composition prepared based on the method and application of the pesticide liquid composition. The pesticide liquid composition is obtained by processing in a micro-mixing system. The micro-mixing system realizes the rapid and homogeneous mixing of all components in the pesticide liquid composition; but also realizes the volatilization and release of non-volatile organic compounds in the preparation process.

Description

Preparation method of pesticide liquid composition, pesticide liquid composition prepared based on preparation method and application of pesticide liquid composition
Technical Field
The invention relates to the field of pesticides, in particular to a preparation method of a pesticide liquid composition, the pesticide liquid composition prepared based on the method and application of the pesticide liquid composition.
Background
VOCs are acronyms for Volatile organic compounds (VOLATILE organic Compounds). VOCs in the general sense are commanding organic matters; but the definition in the environmental protection sense refers to an active class of volatile organic compounds, namely, volatile organic compounds which can cause harm. The industrial industries that emit VOC include: petrochemical industry, fine chemical industry, spraying, packaging and printing, medicine and pesticide manufacturing, semiconductor and electronic product manufacturing, artificial board and wooden furniture manufacturing, leather, enameled wire, shoe manufacturing, paint, printing ink, adhesive production and the like, metal casting and the like.
At present, the pesticide liquid composition is prepared by adopting a traditional stirring kettle. The pesticide liquid composition needs to use a large amount of organic solvent, and many pesticide active ingredients are volatile, so that organic waste gas is generated in the preparation of the pesticide liquid composition. The common components of the VOC include hydrocarbons, benzenes, alcohols, ketones, aldehydes, esters, amines, nitriles (cyanides), and the like. The harm caused by the organic waste gas is as follows: lasting harm to the health of production personnel; the discharged organic waste gas is possible to explode, so that potential safety hazards are caused; the emission of organic waste gas can increase the environmental pressure and destroy the ozone layer; the large amount of solvent consumption increases the production cost.
At present, the requirements of safety and environmental protection are more and more strict, in particular to the emission reduction of three wastes. And organic waste gas is inevitably generated when the traditional preparation kettle is used for preparing the pesticide liquid composition.
Therefore, how to provide a method for preparing a pesticide liquid composition which does not generate organic waste gas and reduces the volatilization of the solvent and the active component has become a hot spot of current research.
Disclosure of Invention
The invention provides a preparation method of a pesticide liquid composition, which comprises a preparation method I, a preparation method II or a preparation method III, wherein the preparation method I comprises the following steps:
(1) dissolving an active ingredient in one or more liquid carriers to obtain a fluid 1;
(2) mixing one or more agriculturally acceptable adjuvants to obtain a fluid 2;
(3) the pesticide liquid composition is obtained by pumping the fluid 1 and the fluid 2 into a micro-mixing system.
The preparation method II comprises the following steps:
(1) preheating the active ingredient, one or more liquid carriers and one or more agriculturally acceptable adjuvants until all ingredients are in a liquid fluid;
(2) and directly pumping the fluid into a micro-mixing system for treatment to obtain the pesticide liquid composition.
The preparation method III comprises the following steps:
(1) preheating the active ingredient, one or more liquid carriers and one or more agriculturally acceptable adjuvants until all ingredients are in a liquid fluid;
(2) mixing the active ingredient with one or more liquid carriers to obtain a fluid 1;
(3) mixing one or more agriculturally acceptable adjuvants to obtain a fluid 2;
(4) the pesticide liquid composition is obtained by pumping the fluid 1 and the fluid 2 into a micro-mixing system.
According to the invention, the pesticide liquid composition is prepared by adopting the micro-mixing system, so that volatilization and release of a large amount of solvents and active components can be effectively reduced, and the generation amount of waste gas is obviously reduced, thereby reducing the pollution to the environment; meanwhile, the pesticide liquid composition prepared by the micro-mixing system has uniform and stable active ingredient content, and realizes the rapid and homogeneous mixing of all components in the pesticide liquid composition.
Preferably, the preheating temperature in the preparation methods II and III is a temperature sufficient for all components to be in a liquid state; preferably, the preheating temperature is 40 ℃ to 100 ℃, for example, 40 ℃, 50 ℃, 60 ℃, 70 ℃, 80 ℃, 90 ℃, 100 ℃, preferably 60 ℃ to 100 ℃.
In the preparation method of the pesticide liquid composition, the active component accounts for 1% -80%, more preferably 5% -80%, more preferably 10% -80%, more preferably 15% -80%, more preferably 20% -80%, more preferably 25% -80%, more preferably 30% -80%, more preferably 35% -80%, more preferably 40% -80%, more preferably 50% -80% of the mass of the pesticide liquid composition.
In the preparation method of the pesticide liquid composition, the active components can also account for the following components in the mass percentage of the pesticide liquid composition: 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%, 34%, 35%, 36%, 37%, 38%, 39%, 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%, 49%, 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 61%, 62%, 63%, 64%, 65%, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79%, 80%.
In the method for preparing the pesticide liquid composition, the active component accounts for preferably 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 61%, 62%, 63%, 64%, 65%, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79%, 80% of the mass of the pesticide liquid composition.
The active components comprise bactericides, insecticides, herbicides, plant growth regulators and the like.
In the pesticide liquid composition, the auxiliary agent is selected from an emulsifier, a dispersant, a thickener, an antifreeze, a preservative, a defoaming agent and other auxiliary agents.
The emulsifiers include ionic and nonionic emulsifiers such as fatty acid esters, fatty alcohol esters, ethers, alkyl sulfonates, and aryl sulfonates.
The auxiliary agent accounts for 2-10% of the mass of the pesticide liquid composition, and can be 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, and preferably 5-8%.
The liquid carrier includes an organic diluent or solvent. And may be polar or non-polar.
The invention also provides a micro-mixing system for preparing the pesticide liquid composition, which comprises a feeding device, a micro-mixing device and a storage tank; the feeding device is connected with the feed inlet of the micro-mixing device, and the discharge outlet of the micro-mixing device is connected with the storage tank.
Preferably, the invention also provides a micro-reaction system for preparing the pesticide emulsion in water, which comprises a feeding device, a micro-mixing device, a residence time distribution device and a storage tank; the feeding device is connected with the feed inlet of the micro-mixing device, the discharge outlet of the micro-mixing device is connected with the feed inlet of the residence time distribution device, and the discharge outlet of the residence time distribution device is connected with the storage tank.
Further, the micro-mixing device comprises a micro-reactor; the feeding device comprises a liquid tank and a constant flow pump connected with the liquid tank. The micro-mixing device is used for quickly and uniformly mixing the fluid.
Furthermore, a mixing unit internal part is arranged in the microreactor, and the mixing unit internal part is a mixing unit body fixed in the microchannel and used for changing the flowing state of the fluid in the tube and further enhancing the mass transfer and mixing of the mixture. The mixing unit internals may be passive micromixers with individual microchannel dimensions in the range of 3 μm to 3000 μm, such as T-type, star-type, jet impinging flow type, jet rotary type, falling film type, multiple cross-cut type, comb type, valve type, stacked type, tubular type and other types.
Further, the residence time distribution device includes a residence time distribution unit, and further preferably further includes an ultrasonic generator disposed outside the residence time distribution unit. The residence time distribution device is used for increasing the residence time of the fluid so as to obtain better emulsification effect.
Furthermore, the residence time distribution device further comprises an ultrasonic groove surrounding the residence time distribution unit, and the ultrasonic generator is installed in the ultrasonic groove.
Preferably, the ultrasonic tank comprises an inner tank and an outer tank which are connected together, and the ultrasonic generators are uniformly installed in the outer tank in a staggered manner, so that the ultrasonic range uniformly covers the microreactor; the whole residence time distribution unit penetrates through the inner groove and is connected with the inner groove in a sealing way; the inner tank realizes circulation of circulating fluid through the water inlet and the water outlet. Preferably, the fluid is water, and is used for regulating and controlling the temperature during mixing, and the temperature of the water can be regulated according to the requirement.
The present invention also provides a pesticide composition comprising:
(1) the obtained pesticidal liquid composition was prepared according to the preparation method as described above;
(2) other agriculturally acceptable adjuvants.
The invention also provides application of the pesticide liquid composition prepared by the preparation method in controlling diseases, pests and weeds in crop protection.
The invention also provides application of the pesticide composition in preventing and controlling diseases, pests and weeds in crop protection.
The pesticide liquid composition or the pesticide composition provided by the invention can be directly applied or applied after being diluted by water.
Compared with the prior art, the invention has at least the following beneficial effects:
(1) according to the invention, the pesticide liquid composition is prepared by adopting a micro-mixing technology, so that volatilization and release of a solvent and an active component in a preparation process can be effectively reduced or reduced, and the generation amount of waste gas is obviously reduced, thereby greatly reducing pollution to the environment;
(2) the pesticide liquid composition prepared by the micro-reaction system has uniform and stable active ingredient content, clear and transparent appearance and uniform phase without layering;
(3) the preparation method provided by the invention can be adjusted correspondingly according to the characteristics of the active components in the pesticide liquid composition, and various pesticide active components can be suitable for the micro-reaction system in the invention.
Drawings
FIG. 1 is a schematic diagram of a micro-reaction system 1 according to an embodiment of the present invention, in which 1 is a liquid tank, 2 is a constant flow pump, 3 is a micro-mixing device, and 12 is a storage tank.
FIG. 2 is a schematic diagram of micro-reaction systems 2 and 3 in an embodiment of the present invention, wherein 1 is a liquid tank, 2 is a constant flow pump, 3 is a micro-mixing device, 4 is a residence time distribution device, and 12 is a storage tank.
Fig. 3 is a schematic view of a residence time distribution apparatus in a micro-reaction system 3 in an embodiment of the present invention, in which 5 is a residence time distribution unit, 6 is an inner tank of an ultrasonic tank, 7 is an outer tank of the ultrasonic tank, 8 is an ultrasonic generator, 9 is a water inlet of the ultrasonic inner tank, 10 is a water outlet of the ultrasonic inner tank, and 11 is an internal member of the residence time distribution unit.
The present invention is described in further detail below. The following examples are merely illustrative of the present invention and do not represent or limit the scope of the claims which follow.
Detailed Description
The invention provides a preparation method I of a pesticide liquid composition, which comprises the following steps:
(1) dissolving an active ingredient in one or more liquid carriers to obtain a fluid 1;
(2) mixing one or more agriculturally acceptable adjuvants to obtain a fluid 2;
(3) the pesticide liquid composition is obtained by pumping the fluid 1 and the fluid 2 into a micro-mixing system.
Or a second preparation method II is adopted, which comprises the following steps:
(1) preheating the active ingredient, one or more liquid carriers and one or more agriculturally acceptable adjuvants until all ingredients are in a liquid fluid;
(2) and directly pumping the fluid into a micro-mixing system for treatment to obtain the pesticide liquid composition.
Or a third preparation method III is adopted, which comprises the following steps:
(1) preheating the active ingredient, one or more liquid carriers and one or more agriculturally acceptable adjuvants until all ingredients are in a liquid fluid;
(2) mixing the active ingredient with one or more liquid carriers to obtain a fluid 1;
(3) mixing one or more agriculturally acceptable adjuvants to obtain a fluid 2;
(4) the pesticide liquid composition is obtained by pumping the fluid 1 and the fluid 2 into a micro-mixing system.
Preferably, the preheating temperature in the preparation methods II and III is a temperature sufficient for all components to be in a liquid state; preferably, the preheating temperature is 40 ℃ to 100 ℃, for example, 40 ℃, 50 ℃, 60 ℃, 70 ℃, 80 ℃, 90 ℃, 100 ℃, preferably 60 ℃ to 100 ℃.
In the preparation method of the pesticide liquid composition, the active component accounts for 1% -80%, more preferably 5% -80%, more preferably 10% -80%, more preferably 15% -80%, more preferably 20% -80%, more preferably 25% -80%, more preferably 30% -80%, more preferably 35% -80%, more preferably 40% -80%, more preferably 50% -80% of the mass of the pesticide liquid composition.
In the preparation method of the pesticide liquid composition, the active components can also account for the following components in the mass percentage of the pesticide liquid composition: 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%, 34%, 35%, 36%, 37%, 38%, 39%, 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%, 49%, 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 61%, 62%, 63%, 64%, 65%, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79%, 80%.
In the method for preparing the pesticide liquid composition, the active component accounts for preferably 50%, 51%, 52%, 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 61%, 62%, 63%, 64%, 65%, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79%, 80% of the mass of the pesticide liquid composition.
The active components comprise bactericides, insecticides, herbicides, plant growth regulators and the like.
The bactericide is selected from: benalaxyl (benalaxyl), metalaxyl (metalaxyl), flutolanil (ofaurace), oxadixyl (oxadixyl), 4-dodecyl-2, 6-dimethylmorpholine (aldimorph), dodine (dodine), moroxydine (dodemorph), fenpropimorph (fenpropimorph), fenpropidin (fenpropidin), guazatine (guazatine), iminoctadine (iminoctadine), spiroxamine (spiroxamine), tridemorph (tridemorph), pyrimethanil (pyrimethanil), mepanipyrim (mepanipyrim), propidium (procydin), cycloheximide (cycloheximide), griseofulvin), kasugamycin (kasumicin), polymalemycin (amamycin), polyoxin (polyoxamycin), streptozocin (triadimenol), fenzanol (benzoxazole), fluquinconazole (fenbuconazole), fluquinconazole (fenpyroxadine), fluquine (fenpyroxadine), fluzone (benzoxazole), fluzone (benzoxazole) (trifloxystrobin), fluzone (benzoxazole) (fluzone), fluzone (benzoxazole) (fluzone), fluzone (, Myclobutanil (myclobutanil), penconazole (penconazole), propiconazole (propiconazole), prochloraz (prochlloraz), prothioconazole (prothioconazole), tebuconazole (tebuconazole), triadimefon (triadimion), triadimenol (triadiminol), triflumizole (triflumizole), triticonazole (triticonazole), 5-chloro-7- (4-methylpiperidin-1-yl) -6- (2,4, 6-trifluorophenyl) - [1,2,4] triazolo [1,5-a ] pyrimidine, iprodione (iprodione), metconazole (myclobulin), procymidone (procymidone), dimeticone (vinclozolin), ferbam, sodium (zebramam), maneb (zineb), zinc (metiram), propiram (propiram), zinc (propineb), propineb (propiram (propineb), propineb (propineb), propiram (propineb (propiram), propiram (propiram), propineb), propiram (propiram), propineb (propineb), propineb (propiram), propiram (, Benomyl (benomyl), boscalid (boscalid), carbendazim (carbendazim), carboxin (carboxin), carboxin (oxacarbxin), cyazofamid (cyazofamid), dazomet (dazomet), dithianon (dithianon), oxazolone (famoxadone), fenamidone (fenamidone), isopimadyl alcohol (fenarimol), fuberidazole (furadizole), flutolanil (flutolanil), furametpyr (furametpyr), metofenamide (mepronil), flufenarimol (nuarimol), probenazole (probenazole), proquinazine (proquinazid), praziquantel (pyrofenox), pyroquine (pyroquinyn), quinoxyfen (quinoxyfen), silthiofamid (silthiofam), thiflufen (fenpyrad), thifluzamide (fenpyroxate), thifluzamide (fenpyradifloram), thifluzamide (fenpyroxate), thiflufen (fenpropiconazole), thiflufen (fenpyroxate (fenpropiconazole), thiflufen (fenpyroxate (fenpropiconazole), thiflufen (fenpropiconazole), thiflufen (fenpropiconazole), thifenpropiconazole (fenpropiconazole), thiflufen), thifenpropiconazole (fenpropiconazole), thifenpropiconazole (fenpropiconazole (fenpropi, Bacteriostatic agent (dichlofluanid), folpet (folpet), tolylfluanid (tolyfluoride), dimethomorph (dimethomorph), fluorobiphenyl (flumetor), flumorph (flumorph), azoxystrobin (azoxystrobin), dimoxystrobin (dimoxystrobin), fluoxastrobin (fluoxastrobin), kresoxim-methyl (kresoxim-methyl), metominostrobin (metominostrobin), orysastrobin (orysastrobin), picoxystrobin (picoxystrobin), trifloxystrobin (trifloxystrobin), thiadiazol-S-methyl, benthiavalicarb (benthiavalicarb), cloxamide (propamid), chlorothalonil (cyclofenthiuron), cyflumizomid (cyflumizol), fenpyrad (fenpyrad), fenpyrad (fenflurazole), fenpyrad (fenflurazole), fenpyrad (fenpyrad), fenpyrad (fenflurazole), fenpyrad (cyflufenoxaflufenoxaflufenoxafen), fenpyrad (cyhalonil), fenflurazole), fenpyrad (fenflurazole), fenpyrad (fenflurazole), fenflurbenoxanil (fenpyrad (fenflurazole), fenflurfenflurfenflurfenflurfenflurfenpyrad (, Metrafenone (metrafenone), pencycuron (pencycuron), propamocarb (propamocarb), tetrachlorophthalide (phthalide), tolclofos-methyl (tolclofos-methyl), quintozene (quintozene), zoxamide (zoxamid).
The herbicide is selected from: acetochlor (acetochlor), acibenzolar (acibenzolar), benzothiadiazole (acibenzolar-S-methyl), acifluorfen (acifluorfen), aclonifen (acibenzolar), alachlor (alachlor), diachlor (acibenzolar), diclofen (alloxydim), ametryn (ametryn), amicarbazone (amicarbazone), amidosulfuron), aminopyralid (amicarbazolid), fentrazole (amicarbazone), anilofos (anilofos), asulam (amicarbazone), amicarbazone (amicarbazone), pyrithion (amicarbazone), pyriminon (amicarbazone), pyribenzosulfuron (amicarbazone), bensulfuron (fensulfuron), bensulfuron (pyrazosulfuron), pyrisulfuron (pyrazosulfuron (butazone), pyribenzofenapyr (butazone), pyriftazone (butazone), pyribensulfuron (butazone), pyribensulfuron) (bensulfuron), bensulfuron) (ben, Butralin (butralin), cafenstrole (cafenstrole), fenpyroxate (carbbetamide), carfentrazone (carfentrazone), chlorimuron-ethyl (chlorimuron-ethyl), chlormequat chloride (chlorimuron-chloride), chlortoluron (chlorotoluron), chlorsulfuron (chlorimuron-ethyl), cinosulfuron (cinosulfuron), clethodim (cycloxauron), clethodim (clomazone), clomeprop), clopyralid (clopyralid), cyanazine (cyazone), cyprodinamide (cyformide), cyprosulfuron (cyclosulfuron), cycloxydim (cycloxydim), cycloxydim (cyhalon-ethyl), fenflurazone (cyhalon), fentrazone (fentrazone), fenflurazone (fentrazone-ethyl), fenflurazone (fenflurazone-ethyl), fenfluridone (fluridone-methyl-ethyl), fenfluridone (fluridone), fentrazone (cyhalozone), fentrazone (fentrazone), fentrazone, fenfluridil (fentrazone), fenfluridil-ethyl, fenfluridil (fenfluridil, fenfluridil, Dimethenamid (dimethachlor), isovaleryl (dimethamarbn), diphenyfen (diphenamid), ipratron (repropetyn), diquat (diquat), diuron (diuron), ethametsulfuron (ethametsulfuron), ethofencuron (ethofenpron), fenoxaprop (ethephon), fenoxaprop (fenoxaprop-P), fenoxaprop (fenoxaprop-ethyl), fentrazamide (fentrazamide), flazasulfuron (flufenuron), flufensulfuron (flufenfluridone), flufenpyraflufen (flufenpyraflufen-P), flufenpyraflufen (flufenpyraflufen-ethyl), flufenpyraflufen (flufenpyraflufen-P), flufenpyraflufen-ethyl (flufenpyraflufen-P), flufenpyraflufen (flufen-ethyl), flufen-ethyl (flufen-ethyl), flufenfluridone (flufen-ethyl), flufen-ethyl (flufen-ethyl), flufenfluridone (flufen-ethyl), flufen-butyl-ethyl (flufen-ethyl), flufen-butyl-ethyl (flufen-butyl fluoride, flufen-ethyl), flufen-butyl-ethyl (flufen-ethyl), flufen-butyl fluoride (flufen-butyl fluoride, flufen-ethyl (flufen, Flumetsulam (flumetsulam), flumioxazin (flumioxazin), flumetsulam (flumipropyn), flumuron (flumeturon), flumetsulam (fluoronifron), fluoroglycofen (fluorodifen), fluoroglycofen (fluoroglycofen), fluridone (fluuridone), fludioxonil (fluridone), fluroxypyr (fluroxypyr), flurtamone (fluutamide), oxamide (fluthiamide), fomesafen (fomesafen), glufosinate (glufosinate, glufosinate-ammonium), glufosinate-P (glufosinate-P), glufosinate-P (fluorosulfuron-ammonium), glufosinate-P (fluoroglufosinate-P), glufosinate-ammonium (glyphosate-ammonium), glufosinate-ammonium (glyphosate-P), glufosinate (glyphosate-P (glufosinate), glufosinate-P (glufosinate-P), glufosinate-P (glyphosate-P), glufosinate-P (glufosinate-P-glufosinate), glufosinate-P (glufosinate-P, glufosinate-P-glufosinate, glufosinate, fluazifop-P-ethoxyethyl, haloxyfop-methyl, haloxyfop-P-methyl, hexazinone, imazamethabenz-z, imazamethabenz-P-methyl, imazamox, imazapic, imazapyr, imazazapyr, imazazapic, imazapyr-amonium, imazapyr, imazosulfuron, isofenuron, isofenpyrofenuron, isofenpyroxene, isofenpyrofenuron, isofenpyrazone, isofenpyrofenuron, isofenpyrofenpyrazone, isofenpyrofenpyrofenpyrazone, isofenpyrofenpyrazone, isofenpyrofenpyrofenpyrazone, isofenpyrofenpyrazone, isofenpyrofenpyrozone, isofenpyrozone, or isofenpyrozone, mepiquat-chloride, mesosulfuron (mesosulfuron-methyl), mesotrione (mesotrione), methabenzthiazuron (methabenzthiazuron), metamitron (metamifop), metamitron (metazachlor), imazachlor (methazachlor), imazapyr (methazole), metsulfuron (methapyrosulfuron), benzoxyfone (methaxyphenone), metsylmeturon (methadyron), metolachlor (methachlloruron), metosulam (metolachlor), metosulam (S-metolachlor), metosulam (metosulam), metoxuron (metoxuron), metribuzin (metribuzin), metsulron (metosulron-methyl), metosulam (metosulam), metosulam (metosultone), metribuzin (metosultone-methyl), metosultone (metosultone), metosultone (meto, paraquat dichloride, pendimethalin (pendimethalin), pentoxazone (pentoxazone), pethoxamid (petoxamid), picloram (picloram), picolinafen (picolinafen), pinoxaden (pinoxaden), piperophos (piptophos), pretilachlor (pretilachlor), probenazole (probenazole), flumetsulam (profluorazole), cyhalonil (profluoraline), promethazine (profluoraline), profenodim (profenodim), propyzamide (propanamide), propanil (propanamide), promethazine (propazone), propyzamide (propyzamide), bensulfuron (pyrazosulfuron), pyrithion (pyrazosulfuron), pyrithiobac (pyraflufen), pyrithion (pyrazosulfuron), pyribenzopyrithion (pyrazosulfuron-ethyl), pyrithion (pyrazosulfuron (pyrazone), pyriproxyfen (pyrazone (pyrazofos), pyriproxyfen (pyrazone), pyriproxyfen (pyrazofos) and pyrifos (pyrazofos) s-ethyl), pyrithion (pyrazofos) and pyrithion (pyrazosulfuron), pyribencarb-pyrithion (pyrazofenoxathion (pyrazosulfuron), pyrithion (pyrazofenoxas (pyrazofenoxathion (pyrazofenoxas), pyribencarb, pyribenazol-pyribencarb), pyrithion (pyrazone), pyrithio, Pyriminobac-methyl, pyrithiobac-methyl, pyroxasulfone, pyroxsulam, quinclorac, quizalofop-P-ethyl, rimsulfuron, bensulfuron, saflufenacil, sec-butyl, sethoxydim, sulforon, thifensulfuron, sulflururon, metosuluron, thifensulfuron-methyl, thifensulfuron-ethyl, thifensulfuron-methyl, thifensulfuron-ethyl, thiuron, thifensulfuron-methyl, thifensulfuron-ethyl, thiuron, thifensulfuron-methyl, thifensulfuron-ethyl, thiuron, thifensulfuron-methyl, thifensulfuron-, Trifloxysulfuron (trifloxysulfuron-sodium), trifluralin (trifluralin), triflusulfuron (triflusulfuron), triflusulfuron methyl ester (triflusulfuron-methyl), tritoluron (trimeturon), trinexapac (trinexapac-ethyl), triflusulfuron (tritosulfuron), uniconazole (uniconazole).
The insecticide is selected from: abamectin (Abamectin), Emamectin benzoate (Emamectin benzoate), Ivermectin (Ivermectin), milbemectin (milbemertin), Spinosad (Spinosad), Spinetoram (Spinetoram), Cartap (Cartap), monosultap (Thiosultap-monosodium), Thiocyclam (Thiocyclam), bisthiosultap-sodium (Thiosultap-sodium), Chlorantraniliprole (chloantraniliprole), Cyantraniliprole (Cyantraniliprole), Flubendiamide (Flubendiamide), Buprofezin (Buprofezin), Chlorfluazuron (chloflurone), Dicyclanil (Dicyclanil), Diflubenzuron (Diflubenzuron), Flufenoxuron (flufenoxauron), flufenoxazide (flufenozide), thiofenozide (teflufenozide), flufenozide (teflufenozide), teflufenozide (teflufen), flufenozide (teflufenozide), flufenozide (flufenozide), flufenozide (flufenozide), flufenozide (flufenozide, Thiacloprid (Thiacloprid), Imidacloprid (Imidacloprid), Acetamiprid (Acetamiprid), Nitenpyram (nitenpyrad), Dinotefuran (Dinotefuran), meperidine (Paichongding), Imidaclothiz (Imidaclothiz), Indoxacarb (Indoxacarb), Ethiprole (Ethiprole), Fipronil (Fipronil), Tebufenpyrad (Tebufenpyrad), Tolfenpyrad (Tolfenpyrad), Chlorfenapyr (Chlorfenapyr), spirodiclofen (Spiroesifen), Spirotetramat (Spiromesfen), Spirotetramat (Spirotetramat), Diafenthiuron (Diafenthiuron), Amitraz (Amitraz), Bifenthrin (Bifenthrin), cyhalothrin (Cyhalothrin), high-efficiency cyhalothrin (Lafenthifenthiuron), Fenpropathrin (Fenpropathrin), tebuthrin (fenthiocarb), tebufenothrin (fenthiocarb), tebufenofos (fenthion (fenthiocarb), tebufenofos (fenthiocarb (fenpyrad (fenthiocarb), tebufenofos (fenthiocarb), tebufenofos (fenpyrad (fenthiocarb), tebufenocarb (fenthiocarb), tebufenocarb, Chlorpyrifos (Chlorpyrifos), Methidathion (Methidathion), Triazophos (Triazophos), Fenitrothion (Fenitrothion), Profenofos (Profenofos), Isoprothiolane (Isoprothiolane), Metaflumizone (Metaflumizone), Hexythiazox (Hexythiazox), Fenpyroximate (Fenpyroximate), Pyriminostrobin (Pyriminostrobin), Cyflumetofen (Cyflumetofen), Cyenopyrafen (Cyenopyrafen), Etoxazole (Etoxazole), biphenylcarbonitrile (Bifenazate), Metam (Metam).
The plant growth regulator comprises: ethrel (Ethrel), Gibberellins (Gibberellins), Chlormequat chloride (chloremaat chloride), indoleacetic acid (β -indoleacetic acid), trinexamide (Inabenfide), Flumetralin (Flumetralin), Kinetin (Kinetin), propionyl Brassinolide (epichololone), Brassinolide (Brassinolide).
Preferred active ingredients of the present invention are selected from: abamectin (Abamectin), emamectin benzoate (Emametin benzoate), Milbemectin (Milbemectin), Spinosad (Spinosad), buprofezin (Buprofenzin), Dicyclanil (Dicyclnil), Fenoxycarb (Fenaxycarb), Pyriproxyfen (Pyriproxyfen), Pyridalyl (pyridall), Acetamiprid (Acetaprid), Nitenpyram (Nitenpyram), Indoxacarb (Indoxacrb), Tebufenpyrad (Tebufenpyrad), Tolfenpyrad (Tolfenpyrad), pyriminostrobin (Pyrimidefen), Chlorfenapyr (Chlorfenapyr), Spirodiclofen (Spirodifenofen), Spirodiclofen (Cyhalothrin), spirotetramat (Cyhalothrin), spirotetramine (Cyhalothrin), Cyfluthrin (Cyhalothrin), Cyhalothrin (Cyhalothrin), Cyhalothrin (Cyhalothrin), Cyhalothrin (Cyhalothri, Cis-cypermethrin (Alpha-cypermethrin), Beta-cypermethrin (Beta-cypermethrin), zeta-cypermethrin (zeta-cypermethrin), deltamethrin (Delmethrin), Fenpropathrin (Fenpropathrin), Fenvalerate (Fenvalerate), Esfenvalerate (Esfenvalerate), Phenothrin (Phenothrin), Tefluthrin (Tefluthrin), Tetramethrin (Tetramethrin), prothiocarb (Benfuracarb), Carbosulfan (Carbosulfan), Pirimicarb (Pirimicarb), gossypyr (Alanycarb), Methomyl (Methomyl), Oxamyl (Oxamyl), Metolcarb), oryzanol (phenytoin), pyrathion (pyrathiofenthion), pyrathion (pyrazofos), pyrazothion (pyrazothion), Chlorpyrifos (Chlorpyrifos), thiofenthiofos (thiopyrathiofos (thiofos), thiofenthiopyrathiofos (thiofos), thiofenthiopyrazone (thiofos), thiopyrathiofos (thiothiofos (thiopyrathiofos), thiothiothiopyrathiofos (thiothiothiothiothiothiothiofos (thiothiothiothiothiothiofos), thiopyrad (thiothiothiothiothiothiothion (thiothiothiothiothiothiothiothiothion), thiothiopyrad (thiothiothiothiothiothiothiothion (thiothiothiothiothiothiothiothiothion), thiothiothiothiothiothiothiothiothiothiothiothion (thiothiothiothiothiothion (thiothiothiothiothiothiothiothiothion), thiothiothiothiothiothion (thiothiothiothiothiothiothiothiothion (thiothiothiothio, Fenpyroximate (fenpyroxim), Cyflumetofen (Cyflumetofen), Cyenopyrafen (Cyenopyrafen), Etoxazole (Etoxazole), Bifenazate (Bifenazate), Fosthiazate (Fosthiazate), Metam (Metam), Penoxsulam (Penoxsulam), Pyraclonil (Pyraclonil), Oxadiazon (oxadiazinon), Pentoxazone (penoxcarbazone), Carfentrazone-ethyl, Fentrazamide (Fentrazamide), Butafenacil (Butafenacil), flumiclorafen (Flumiclorac-pentyl), Hexazinone (Hexazinone), butafenazate (butrydim), Clethodim (Clethodim), Cycloxydim (cyclofenfluroxypyr), thion (fluorofen), fenfluroxypyr (clofen), Fluroxypyr (clofenfluroxypyr), cyhalofen (Fluroxypyr), Fluroxypyr (Fluroxypyr), clofenan (Fluroxypyr), cyhaloxyfen (Fluroxypyr), Fluroxypyr (clofenan (Fluroxypyr), clofenan (clofenan), clofenan (Fluroxypyr), clofenamate), clofenap (clofenap, clofenap-butyl (clofenap, clo, Fenoxaprop-P-ethyl, Fluazifop-butyl, Quizalofop-P-ethyl, Flufenacet (Picolinafen), Flufenacet (Flufenacet), Acetochlor (Acetochlor), Alachlor (Alachlor), Butachlor (Butachlor), Metazachlor (Metazachlor), Metolachlor (Metolachlor), Metolachlor (S-Metolachlor), Pretilachlor (Propisochlor), metofenacet (therochlor), Pendimethalin (penetham), Trifluralin (Trifluralin), thiobencarb (thiobency), isoxaflutole (Clomazone), indene (indoxachlor), flufenamid (fenfluramine), cyhalonil (Metominostrobin), pyrim (Fluoxastrobin), pyrimethanil (fenaminostrobin), pyrimethanil (trifloxystrobin), pyrimethanil (fenoxastrobin), pyrimethanil (fenoxastrobil), pyrimethanil (fenoxastrobin (fenoxastrobil), pyrimethanil (fenoxastrobil), pyri, Difenoconazole (Difenoconazole), Flusilazole (Flusilazole), Myclobutanil (Myclobutanil), Penconazole (penconazol), Propiconazole (propiconazol), Tetraconazole (Tetraconazole), Imazalil (Imazalil), Prochloraz (Prochloraz), Triflumizole (Triflumizole), pyrisoxazole (SYP-Z048), Hymexazol (Hymexazol), Dodemorph (Dodemorph), Fenpropimorph (Fenpropimorph), Tridemorph (Tridemorph), Cyprodinil (Cyprodinil), diflumetominostrobin (diflumetorim), pyrimethanil (pyrimethanil), Propamocarb (Propamocarb), isodimethomone (iprobenfobes), Pyrazophos (Pyrazophos), propazofam (propazofam), propazofamid (butamol), pyrimethanil (isoproxylon), Isoprothiolane (Isoprothiolane).
In the preparation method of the pesticide liquid composition, the auxiliary agent comprises a hydrophobic auxiliary agent or a hydrophilic auxiliary agent; comprises the auxiliary agents such as an emulsifier, a dispersant, a thickening agent, an anti-freezing agent, a preservative, a defoaming agent, an anti-flocculating agent, a coloring agent and the like.
The emulsifier includes ionic and nonionic emulsifiers, such as fatty alcohol polyoxyethylene ether, polyoxyethylene alkylaryl ether, polyoxyethylene higher fatty acid ester, phosphoric acid ester of polyoxyethylene alcohol or phenol, fatty acid ester of polyhydric alcohol, alkylaryl sulfonic acid, naphthalene sulfonic acid polymer, lignosulfonate, branched copolymer of high molecular comb, butyl naphthalene sulfonate, alkylaryl sulfonate, sodium alkylsulfosuccinate, oils and fats, polyacrylate such as condensate of fatty alcohol and ethylene oxide, alkyl taurate, etc., and protein hydrolysate.
Thickeners such as xanthan gum, magnesium aluminum silicate, gelatin, starch, cellulose methyl ether, polyvinyl alcohol, polyvinyl acetate and natural phospholipids (e.g., cephalin and lecithin) as well as synthetic phospholipids, bentonite, sodium lignosulfonate and like adjuvants may be used to dispersively stabilize, attach and/or bind the active ingredient.
Wherein the antifreezing agent can be selected from ethylene glycol, propylene glycol, glycerol, and sorbitol.
As the defoaming agent, a silicone defoaming agent can be used.
Colorants which may be used, for example, inorganic pigments such as iron oxide, titanium oxide and prussian blue; and organic pigments/dyes: alizarin dyes, azo dyes, and metal phthalocyanine dyes; and trace elements such as iron, manganese, boron, copper, cobalt, molybdenum and zinc salts.
Optionally, the pesticidal liquid composition according to the present invention may further comprise other additional adjuvants, such as protective colloids, binders, thixotropic agents, penetrants, stabilizers, masking agents.
In the preparation method of the pesticide liquid composition, the liquid carrier comprises an organic diluent or a solvent. The liquid carrier may be polar or non-polar, such as water, alcohols (e.g., methanol, ethanol, isopropanol, butanol, ethylene glycol, etc.), ketones (e.g., acetone, methyl ethyl ketone, diisobutyl ketone, cyclohexanone, etc.), ethers (e.g., diethyl ether, methyl cellulose, tetrahydrofuran, etc.), aliphatic hydrocarbons (e.g., kerosene, mineral oil, etc.), aromatic hydrocarbons (e.g., benzene, toluene, xylene, mineral spirits, alkyl naphthalenes, chlorinated aromatic hydrocarbons, chlorinated aliphatic hydrocarbons, chlorobenzene, etc.), halogenated hydrocarbons, amides, sulfones (e.g., dimethyl sulfoxide), mineral and vegetable oils, animal oils, etc.
The invention provides a micro-reaction system for preparing a pesticide liquid composition, which comprises a feeding device, a micro-mixing device and a storage tank, wherein the feeding device is arranged on the micro-mixing device; the feeding device is connected with the feed inlet of the micro-mixing device, and the discharge outlet of the micro-mixing device is connected with the storage tank.
Preferably, the above-mentioned micro-mixing device comprises a microreactor which can be used for the rapid homogeneous mixing of the fluid 1 and the fluid 2; as for the specific selection of the microreactor, the skilled person can make corresponding adjustments according to the actual needs.
Further preferably, a mixing unit internal member is arranged in the micromixer, and the mixing unit internal member is a mixing unit body fixed in the microchannel and used for changing the flow state of the fluid in the tube and further enhancing the mass transfer mixing of the mixing body. The mixing unit internals may be passive micromixers with individual microchannel dimensions in the range of 3 μm to 3000 μm, such as T-type, star-type, jet impinging flow type, jet rotary type, falling film type, multiple cross-cut type, comb type, valve type, stacked type, tubular type and other types.
In micromixers, the tube diameter is an important factor influencing mass transfer. The time required for complete mixing of the fluid is proportional to the square of the mass transfer distance, and the smaller the channel size of the micro-mixing, the shorter the time required for complete mixing of the fluid, and the better the mass transfer effect. Preferably, the microreactor in the micro-mixing device is modified to have a single microchannel diameter of 3 μm to 3000 μm to achieve rapid mass transfer mixing of two or more mixing solutions such that the materials are microscopically homogeneously mixed in an amount of time on the order of less than 1 second.
Since micromixing is the simultaneous contact of the oil phase and the aqueous phase at a fixed ratio at any time, it is possible to accurately adjust the particle size range of the emulsion by precisely controlling the pressure of the pump. The micromixer can achieve the nanometer emulsion fineness by the design of an internal channel structure, the input of high pump pressure energy and the combination of external high-power ultrasound. The pressure of the pump is adjustable within the range of 0.1-50 Mpa.
In the micromixer, the flow rate is a key factor influencing the emulsification effect, the larger the flow rate, the higher the input energy, the better the emulsification effect, and the shorter the time required for complete mixing. The total flow rate can be controlled at 40-400mL/min, such as 40mL/min, 50mL/min, 60mL/min, 80mL/min, 100mL/min, 150mL/min, 200mL/min, 250mL/min, 300mL/min, 350mL/min, 400mL/min, preferably 50-380mL/min, more preferably 80-320mL/min, more preferably 100-300mL/min, more preferably 120-280mL/min, more preferably 150-260 mL/min.
Preferably, the feeding device comprises a liquid tank and a constant flow pump connected with the liquid tank.
Preferably, the invention also provides a micro-reaction system for preparing the pesticide liquid composition, which comprises a feeding device, a micro-mixing device, a residence time distribution device and a storage tank; the feeding device is connected with the feed inlet of the micro-mixing device, the discharge outlet of the micro-mixing device is connected with the feed inlet of the residence time distribution device, and the discharge outlet of the residence time distribution device is connected with the storage tank.
Further, the residence time distribution apparatus includes a residence time distribution unit.
The residence time distribution device is used for increasing the residence time of the fluid, and can obtain better emulsification effect. The residence time distribution unit is internally provided with residence time distribution unit internals for changing the flowing state of the fluid in the pipe and further enhancing the mass transfer and mixing of the mixture. The unit internals may be passive micromixers with individual microchannel dimensions in the range from 3 μm to 3000 μm, such as T-type, star-type, jet impinging flow type, jet rotary type, falling film type, multiple cross-cut type, comb type, valve type, stacked type, tubular type and other types.
Further, the residence time distribution device comprises a residence time distribution unit and an ultrasonic generator arranged outside the residence time distribution unit.
Furthermore, the residence time distribution device further comprises an ultrasonic groove surrounding the residence time distribution unit, and the ultrasonic generator is installed in the ultrasonic groove. The frequency of the ultrasonic wave can be regulated and controlled between 20KHz and 120KHz, and the power of the ultrasonic wave can be regulated and controlled between 100W and 1000W.
Preferably, the ultrasonic tank comprises an inner tank and an outer tank which are connected together, and the ultrasonic generators are uniformly installed in the outer tank in a staggered manner, so that the ultrasonic range uniformly covers the microreactor; the whole residence time distribution unit penetrates through the inner groove and is connected with the inner groove in a sealing way; the inner tank realizes circulation of circulating fluid through the water inlet and the water outlet. Preferably, the fluid is water, and is used for regulating and controlling the temperature during mixing, and the temperature of the water can be regulated according to the requirement. The circulating water functions not only as a temperature condition of the residence time distribution apparatus but also as a propagation medium of the ultrasonic wave. The mixing temperature is 10 ℃ to 100 ℃, for example, 10 ℃, 20 ℃, 35 ℃, 46 ℃, 70 ℃, 80 ℃, 100 ℃.
The invention also provides a pesticide composition, which comprises the pesticide liquid composition prepared by the preparation method and other agriculturally acceptable auxiliaries.
The invention provides application of the pesticide liquid composition prepared by the method in controlling diseases, pests and weeds in crop protection.
The invention also provides application of the pesticide composition in preventing and controlling diseases, pests and weeds in crop protection.
The pesticidal liquid composition according to the present invention may be applied in a conventional manner by using techniques well known to those skilled in the art. Suitable techniques include spraying, atomizing or pouring. The type of application depends in a well-known manner on the intended purpose; in any case, the technique should ensure the best possible distribution of the active ingredient.
The technical scheme of the invention is further explained by the specific implementation mode in combination with the attached drawings.
Micro-reaction system 1:
the invention provides a micro-reaction system for preparing a pesticide liquid composition, which has a structure shown in figure 1. The micro-reaction system mainly comprises a feeding device, a micro-mixing device 3 and a storage tank 12; the feeding device is connected with the feeding hole of the micro-mixing device 3, and the discharging hole of the micro-mixing device 3 is connected with the storage tank 12.
In the micro-reaction system, the micro-mixing device 3 is used for mixing the fluid 1 and the fluid 2; the micro-mixing device 3 comprises a micro-mixer; a T-shaped mixing unit internal part is arranged in the micro mixer, and the diameter of a micro channel of the micro mixer is 600 mu m; the feeding device is formed by connecting a liquid tank 1 and a constant flow pump 2.
Preparation of a pesticidal liquid composition by preparation method I, which comprises the following steps:
(1) dissolving an active ingredient in one or more liquid carriers to obtain a fluid 1;
(2) mixing one or more agriculturally acceptable adjuvants to obtain a fluid 2;
respectively placing the prepared fluid 1 and the prepared fluid 2 in a liquid tank of a feeding device;
(3) starting a feeding device, feeding the fluid 1 and the fluid 2 into a micro-mixing device through a constant flow pump according to a certain proportion, and mixing the fluid 1 and the fluid 2 in the micro-mixing device;
(4) and discharging the material from the micro-mixing device into a storage tank, thereby preparing the pesticide liquid composition.
Or the preparation method II is adopted for preparing the pesticide liquid composition, and the preparation method comprises the following steps:
(1) preheating each component to be liquid fluid, and placing the fluid in a liquid tank of a feeding device;
(2) starting a feeding device, feeding the fluids into a micro-mixing device through a constant flow pump according to a certain proportion, and mixing different fluids in the micro-mixing device;
(3) and discharging the material from the micro-mixing device into a storage tank, thereby preparing the pesticide liquid composition.
Preferably, the preheating temperature is a temperature sufficient to render all components in a liquid state; the preheating temperature is 40-100 deg.C, preferably 60-100 deg.C.
Or the preparation method III is adopted to prepare the pesticide liquid composition, which comprises the following steps:
(1) preheating each component to be liquid fluid;
(2) mixing the active ingredient with one or more liquid carriers to obtain a fluid 1;
(3) mixing one or more agriculturally acceptable adjuvants to obtain a fluid 2;
respectively placing the prepared fluid 1 and the prepared fluid 2 in a liquid tank of a feeding device;
(4) starting a feeding device, feeding the fluids into a micro-mixing device through a constant flow pump according to a certain proportion, and mixing different fluids in the micro-mixing device;
(5) and discharging the material from the micro-mixing device into a storage tank, thereby preparing the pesticide liquid composition.
Preferably, the preheating temperature is a temperature sufficient to render all components in a liquid state; the preheating temperature is 40-100 deg.C, preferably 60-100 deg.C.
Micro-reaction system 2:
the present invention provides a micro-reaction system for preparing a pesticide liquid composition, the structure of which is shown in fig. 2. The micro-reaction system mainly comprises a feeding device, a micro-mixing device 3, a residence time distribution device 4 and a storage tank 12; the feeding device is connected with the feed inlet of the micro-mixing device 3, the discharge outlet of the micro-mixing device 3 is connected with the feed inlet of the residence time distribution device 4, and the discharge outlet of the residence time distribution device 4 is connected with the stock chest 12.
In the micro-reaction system, the micro-mixing device 3 is used for mixing the fluid 1 and the fluid 2; the micro-mixing device 3 comprises a micro-mixer, a T-shaped mixing unit internal part is arranged in the micro-mixer, and the diameter of a micro-channel of the micro-mixer is 600 mu m; the feeding device is formed by connecting a liquid tank 1 and a constant flow pump 2.
In the above-mentioned micro-reaction system, the residence time distribution means 4 comprises a residence time distribution unit 5. The residence time distribution unit is internally provided with residence time distribution unit internals for changing the flowing state of the fluid in the pipe and further enhancing the mass transfer and mixing of the mixture. The residence time distribution unit is internally provided with a T-shaped mixing unit internal part, and the diameter of a micro-channel of the residence time distribution unit is 600 mu m.
Preparation of a pesticidal liquid composition by preparation method I, which comprises the following steps:
(1) dissolving an active ingredient in one or more liquid carriers to obtain a fluid 1;
(2) mixing one or more agriculturally acceptable adjuvants to obtain a fluid 2;
respectively placing the prepared fluid 1 and the prepared fluid 2 in a liquid tank of a feeding device;
(3) starting a feeding device, feeding the fluid 1 and the fluid 2 into a micro-mixing device through a constant flow pump according to a certain proportion, and mixing the fluid 1 and the fluid 2 in the micro-mixing device;
(4) the discharge of the micro-mixing device enters a residence time distribution device;
(5) and discharging the material from the residence time distribution device into a storage tank, thereby preparing the pesticide liquid composition.
Or the preparation method II is adopted for preparing the pesticide liquid composition, and the preparation method comprises the following steps:
(1) preheating each component to be liquid fluid, and placing the fluid in a liquid tank of a feeding device;
(2) starting a feeding device, feeding the fluids into a micro-mixing device through a constant flow pump according to a certain proportion, and mixing different fluids in the micro-mixing device;
(3) the discharge of the micro-mixing device enters a residence time distribution device;
(4) and discharging the material from the residence time distribution device into a storage tank, thereby preparing the pesticide liquid composition.
Preferably, the preheating temperature is a temperature sufficient to render all components in a liquid state; the preheating temperature is 40-100 deg.C, preferably 60-100 deg.C.
Or the preparation method III is adopted to prepare the pesticide liquid composition, which comprises the following steps:
(1) preheating each component to be liquid fluid;
(2) mixing the active ingredient with one or more liquid carriers to obtain a fluid 1;
(3) mixing one or more agriculturally acceptable adjuvants to obtain a fluid 2;
respectively placing the prepared fluid 1 and the prepared fluid 2 in a liquid tank of a feeding device;
(4) starting a feeding device, feeding the fluids into a micro-mixing device through a constant flow pump according to a certain proportion, and mixing different fluids in the micro-mixing device;
(5) the discharge of the micro-mixing device enters a residence time distribution device;
(6) and discharging the material from the residence time distribution device into a storage tank, thereby preparing the pesticide liquid composition.
Preferably, the preheating temperature is a temperature sufficient to render all components in a liquid state; the preheating temperature is 40-100 deg.C, preferably 60-100 deg.C.
Micro-reaction system 3:
the present invention provides a micro-reaction system for preparing a pesticide liquid composition, the structure of which is shown in fig. 2 and 3. The micro-reaction system comprises a feeding device, a micro-mixing device 3, a residence time distribution device 4 and a storage tank 12; the feeding device is connected with the feed inlet of the micro-mixing device 3, the discharge outlet of the micro-mixing device 3 is connected with the feed inlet of the residence time distribution device 4, and the discharge outlet of the residence time distribution device 4 is connected with the storage tank.
In the micro-reaction system, the micro-mixing device 3 is used for mixing the fluid 1 and the fluid 2; the micro-mixing device 3 comprises a micro-mixer, a T-shaped mixing unit internal part is arranged in the micro-mixer, and the diameter of a micro-channel of the micro-mixer is 600 mu m; the feeding device is formed by connecting a liquid tank 1 and a constant flow pump 2.
In the above-mentioned micro-reaction system, the residence time distribution means 4 is composed of a residence time distribution unit 5 and an ultrasonic generator 8 disposed outside the residence time distribution unit.
The residence time distribution unit 5 is internally provided with residence time distribution unit internals for changing the flowing state of the fluid in the pipe so as to further enhance the mass transfer and mixing of the mixture. The residence time distribution unit internal part is internally provided with a T-shaped mixing unit internal part, and the diameter of a microchannel of the residence time distribution unit internal part is 600 mu m.
The residence time distribution means 4 further comprises an ultrasonic tank surrounding the outside of the residence time distribution unit 5; the ultrasonic generator 8 is installed in the ultrasonic groove. The residence time distribution unit 5 penetrates through the inner groove 6 and is connected with the inner groove 6 in a sealing way; the inner tank 6 is in circulation of the circulating fluid through the inlet 9 and the outlet 10. The fluid is water and is used for regulating and controlling the temperature of reaction liquid during mixing, and the temperature of the water can be regulated according to the requirement. The residence time distribution unit 5 is internally provided with a residence time distribution unit internal part 11, and the residence time distribution unit internal part 11 is a mixing unit body fixed in the residence time distribution unit and used for changing the flowing state of the fluid in the pipe and further enhancing the mass transfer mixing of the fluid 1 and the fluid 2.
Preparation of a pesticidal liquid composition by preparation method I, which comprises the following steps:
(1) dissolving an active ingredient in one or more liquid carriers to obtain a fluid 1;
(2) mixing one or more agriculturally acceptable adjuvants to obtain a fluid 2;
respectively placing the prepared fluid 1 and the prepared fluid 2 in a liquid tank of a feeding device;
(3) starting a circulating water system, and introducing circulating water into the residence time distribution device; meanwhile, starting the ultrasonic waves of the residence time distribution device and adjusting the frequency of the ultrasonic waves; the frequency of the ultrasonic wave can be regulated and controlled between 20KHz and 100KHz, and the power of the ultrasonic wave can be regulated and controlled between 100W and 1000W; the temperature of the circulating water can be adjusted between room temperature and 95 ℃;
(4) starting a feeding device, feeding the fluid 1 and the fluid 2 into a micro-mixing device through a constant flow pump according to a certain proportion, and mixing the fluid 1 and the fluid 2 in the micro-mixing device;
(5) the discharge of the micro-mixing device enters a residence time distribution device;
(6) and discharging the material from the residence time distribution device into a storage tank, thereby preparing the pesticide liquid composition.
Or the preparation method II is adopted for preparing the pesticide liquid composition, and the preparation method comprises the following steps:
(1) preheating each component to be liquid fluid, and placing the prepared fluid in a liquid tank of a feeding device;
(2) starting a circulating water system, and introducing circulating water into the residence time distribution device; meanwhile, starting the ultrasonic waves of the residence time distribution device and adjusting the frequency of the ultrasonic waves; the frequency of the ultrasonic wave can be regulated and controlled between 20KHz and 100KHz, and the power of the ultrasonic wave can be regulated and controlled between 100W and 1000W; the temperature of the circulating water can be adjusted between room temperature and 95 ℃;
(3) starting a feeding device, feeding the fluids into a micro-mixing device through a constant flow pump according to a certain proportion, and mixing different fluids in the micro-mixing device;
(4) the discharge of the micro-mixing device enters a residence time distribution device;
(5) and discharging the material from the residence time distribution device into a storage tank, thereby preparing the pesticide liquid composition.
Preferably, the preheating temperature is a temperature sufficient to render all components in a liquid state; the preheating temperature is 40-100 deg.C, preferably 60-100 deg.C.
Or the preparation method III is adopted to prepare the pesticide liquid composition, which comprises the following steps:
(1) preheating each component to be liquid fluid;
(2) mixing the active ingredient with one or more liquid carriers to obtain a fluid 1;
(3) mixing one or more agriculturally acceptable adjuvants to obtain a fluid 2;
respectively placing the prepared fluid 1 and the prepared fluid 2 in a liquid tank of a feeding device;
(4) starting a circulating water system, and introducing circulating water into the residence time distribution device; meanwhile, starting the ultrasonic waves of the residence time distribution device and adjusting the frequency of the ultrasonic waves; the frequency of the ultrasonic wave can be regulated and controlled between 20KHz and 100KHz, and the power of the ultrasonic wave can be regulated and controlled between 100W and 1000W; the temperature of the circulating water can be adjusted between room temperature and 95 ℃;
(5) starting a feeding device, feeding the fluids into a micro-mixing device through a constant flow pump according to a certain proportion, and mixing different fluids in the micro-mixing device;
(6) the discharge of the micro-mixing device enters a residence time distribution device;
(7) and discharging the material from the residence time distribution device into a storage tank, thereby preparing the pesticide liquid composition.
Preferably, the preheating temperature is a temperature sufficient to render all components in a liquid state; the preheating temperature is 40-100 deg.C, preferably 60-100 deg.C.
Formulation example 133% pendimethalin emulsifiable concentrate
Figure BDA0001712789910000181
Formulation example 245% chlorpyrifos emulsifiable concentrate
Formulation example 310% pyriproxyfen emulsifiable concentrate
Figure BDA0001712789910000183
Formulation example 440% isoprothiolane emulsifiable concentrate
Figure BDA0001712789910000184
Formulation example 545% Prochloraz emulsifiable concentrate
Figure BDA0001712789910000191
Formulation example 625% Tebuconazole emulsifiable concentrate
Figure BDA0001712789910000192
Formulation example 710% bifenthrin emulsifiable concentrate
Formulation example 820% Imidacloprid soluble concentrate
Figure BDA0001712789910000194
Formulation example 924% clethodim emulsifiable concentrate
Figure BDA0001712789910000195
Formulation example 1020% methomyl water aqua
Methomyl 20%
Ethanol 40%
40 percent of water
Preparation example 115% lufenuron emulsifiable concentrate
Figure BDA0001712789910000201
Preparation examples
Preparation method I of microreaction System 1 preparation examples 1-11 were prepared and samples 1-11 were obtained, respectively.
TABLE 1
Figure BDA0001712789910000211
Figure BDA0001712789910000221
Preparation method II of the micro-reaction System 1 was used to prepare formulation examples 1,2, 3, 4, 5, and 9, and samples 12 to 17 were obtained, respectively.
TABLE 2
Figure BDA0001712789910000222
Figure BDA0001712789910000231
Preparation method III of the micro-reaction System 1 preparation examples 1,2, 3, 4, 5, 9 were prepared and samples 18-23 were obtained, respectively.
TABLE 3
Figure BDA0001712789910000241
Preparation method I of microreaction System 2 preparation of formulation examples 1-11 were used to obtain samples 24-34, respectively.
TABLE 4
Figure BDA0001712789910000242
Figure BDA0001712789910000251
Preparation method II of micro-reaction System 2 preparation of formulation examples 1,2, 3, 4, 5, 9, samples 35-40 were obtained, respectively.
TABLE 5
Figure BDA0001712789910000271
Preparation method III of micro-reaction system 2 preparation of formulation examples 1,2, 3, 4, 5, 9, samples 41-46 were obtained, respectively.
TABLE 6
Figure BDA0001712789910000272
Figure BDA0001712789910000281
Preparation method I of microreaction system 3 preparation of formulation examples 1-11 were used to obtain samples 47-57, respectively.
TABLE 7
Figure BDA0001712789910000282
Figure BDA0001712789910000291
Figure BDA0001712789910000301
Preparation method II of microreaction System 3 preparation of formulation examples 1,2, 3, 4, 5, 9, samples 58-63 were obtained, respectively.
TABLE 8
Figure BDA0001712789910000302
Figure BDA0001712789910000311
Formulation examples 1,2, 3, 4, 5, 9 were prepared using method III of micro reaction system 3, and samples 64-69 were obtained, respectively.
TABLE 9
Figure BDA0001712789910000321
The test data in tables 1-9 show that the content of active ingredients in the pesticide liquid composition prepared by the methods I-III of the micro-reaction systems 1-3 is uniform and stable, and the micro-reaction systems 1-3 realize the rapid and homogeneous mixing of the components in the pesticide liquid composition. Particularly, in the preparation process, because the micro-reaction system is a closed mixing system, the volatilization and release of volatile organic compounds are avoided in the preparation process, and the preparation process is safe for operators.
The applicant states that the present invention is described in detail by the above embodiments, but the present invention is not limited to the above detailed structural features, that is, it is not meant to imply that the present invention must be implemented by relying on the above detailed structural features. It will be apparent to those skilled in the art that any modifications to the invention, equivalent substitutions of selected parts of the invention and additions of auxiliary parts, choice of specific ways, etc., are within the scope and disclosure of the invention.

Claims (16)

1. A preparation method of a pesticide liquid composition is characterized by comprising a preparation method I, a preparation method II or a preparation method III;
the preparation method I comprises the following steps:
(1) dissolving an active ingredient in one or more liquid carriers to obtain a fluid 1;
(2) mixing one or more agriculturally acceptable adjuvants to obtain a fluid 2;
(3) pumping the fluid 1 and the fluid 2 into a micro-mixing system to obtain the pesticide liquid composition;
the preparation method II comprises the following steps:
(1) preheating the active ingredient, one or more liquid carriers and one or more agriculturally acceptable adjuvants until all ingredients are in a liquid fluid;
(2) directly pumping the fluid into a micro-mixing system for treatment to obtain the pesticide liquid composition;
the preparation method III comprises the following steps:
(1) preheating the active ingredient, one or more liquid carriers and one or more agriculturally acceptable adjuvants until all ingredients are in a liquid fluid;
(2) mixing the active ingredient with one or more liquid carriers to obtain a fluid 1;
(3) mixing one or more agriculturally acceptable adjuvants to obtain a fluid 2;
(4) and pumping the fluid 1 and the fluid 2 into a micro-mixing system for processing to obtain the pesticide liquid composition.
2. The production method according to claim 1, wherein the preheating temperature in the production methods II and III is a temperature sufficient for all the components to be in a liquid state; preferably, the preheating temperature is 40 ℃ to 100 ℃, preferably 60 ℃ to 100 ℃.
3. The preparation method according to claim 1, wherein the active ingredient accounts for 1% -80%, more preferably 5% -80%, more preferably 10% -80%, more preferably 15% -80%, more preferably 20% -80%, more preferably 25% -80%, more preferably 30% -80%, more preferably 35% -80%, more preferably 40% -80%, more preferably 50% -80% of the mass of the pesticide liquid composition.
4. The preparation method according to claim 1, wherein the adjuvant accounts for 2-10%, preferably 5-8% of the mass of the pesticide liquid composition.
5. The method according to claim 1, wherein the auxiliary agent is selected from any one of an emulsifier, a dispersant, a thickener, an antifreeze, a preservative, and an antifoaming agent, or a mixture of at least two thereof.
6. The method of claim 1, wherein the liquid carrier comprises an organic diluent or solvent.
7. The preparation method according to claim 1, characterized in that the micro-mixing system comprises a feeding device, a micro-mixing device (3) and a storage tank (12); the feeding device is connected with the feeding hole of the micro-mixing device (3), and the discharging hole of the micro-mixing device (3) is connected with the storage tank (12).
8. A method according to claim 7, characterized in that the micro-mixing device (3) comprises a micro-mixer (5) and the feeding device comprises a liquid tank (1) and a constant flow pump (2) connected thereto.
9. The preparation method according to claim 1, characterized in that the micro-mixing system comprises a feeding device, a micro-mixing device (3), a residence time distribution device (4) and a storage tank (12); the feeding device is connected with the feed inlet of the micro-mixing device (3), the discharge outlet of the micro-mixing device (3) is connected with the feed inlet of the residence time distribution device (4), and the discharge outlet of the residence time distribution device (4) is connected with the stock chest (12).
10. The preparation method according to claim 9, characterized in that the micro-mixing device (3) comprises a micro-mixer (5); the feeding device comprises a liquid tank (1) and a constant flow pump (2) connected with the liquid tank; the residence time distribution device (4) comprises a residence time distribution unit (5).
11. The production method according to claim 9, wherein the residence time distribution device (4) includes a residence time distribution unit (5) and an ultrasonic generator (8) disposed outside the residence time distribution unit (5).
12. The method of manufacturing according to claim 11, wherein the residence time distribution device (4) further comprises an ultrasonic tank surrounding the outside of the residence time distribution unit (5), the ultrasonic generator (8) being installed in the ultrasonic tank.
13. The production method according to claim 12, wherein the ultrasonic tank comprises an inner tank (6) and an outer tank (7) connected together, and the ultrasonic generator (8) is installed in the outer tank (7); the whole residence time distribution unit (5) penetrates through the inner groove (6) and is connected with the inner groove (6) in a sealing way; the inner groove (6) realizes circulation of circulating fluid through the water inlet (9) and the water outlet (10).
14. A pesticidal composition, characterized in that the pesticidal composition comprises:
(1) the pesticidal liquid composition obtained by the production method according to claim 1;
(2) other agriculturally acceptable adjuvants.
15. The use of the pesticidal liquid composition obtained by the preparation method according to claim 1 for controlling diseases, pests and weeds in crop protection.
16. Use of a pesticide composition as claimed in claim 14 for controlling pests and weeds in crop protection.
CN201810691214.6A 2018-06-28 2018-06-28 Preparation method of pesticide liquid composition, pesticide liquid composition prepared based on preparation method and application of pesticide liquid composition Pending CN110651783A (en)

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Publication number Priority date Publication date Assignee Title
CN106905260A (en) * 2017-03-02 2017-06-30 西华大学 Method for preparing herbicide flufenacet Intermediate TDA sulfone
CN107136057A (en) * 2017-06-30 2017-09-08 扬州大学 A kind of highly effective and safe pyrethrin nanometer aqueous emulsion and preparation method thereof
CN207025229U (en) * 2017-03-02 2018-02-23 上海千茂化工科技有限公司 Efficiently, high-power diesel, bunker fuel oil microemulsified device
CN107846872A (en) * 2015-05-22 2018-03-27 阿克苏诺贝尔化学品国际有限公司 Arneel SD solvent for agricultural formulations
CN108940145A (en) * 2018-09-20 2018-12-07 中国科学技术大学 Blended micro-capsule is mixed with device
CN110651784A (en) * 2018-06-28 2020-01-07 江苏龙灯化学有限公司 Preparation method of pesticide emulsion in water, emulsion in water prepared based on method and application of emulsion in water

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107846872A (en) * 2015-05-22 2018-03-27 阿克苏诺贝尔化学品国际有限公司 Arneel SD solvent for agricultural formulations
CN106905260A (en) * 2017-03-02 2017-06-30 西华大学 Method for preparing herbicide flufenacet Intermediate TDA sulfone
CN207025229U (en) * 2017-03-02 2018-02-23 上海千茂化工科技有限公司 Efficiently, high-power diesel, bunker fuel oil microemulsified device
CN107136057A (en) * 2017-06-30 2017-09-08 扬州大学 A kind of highly effective and safe pyrethrin nanometer aqueous emulsion and preparation method thereof
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