CN110651187A - 基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物 - Google Patents

基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物 Download PDF

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Publication number
CN110651187A
CN110651187A CN201880012782.7A CN201880012782A CN110651187A CN 110651187 A CN110651187 A CN 110651187A CN 201880012782 A CN201880012782 A CN 201880012782A CN 110651187 A CN110651187 A CN 110651187A
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aki
subject
persistent
threshold
motif chemokine
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Chinese (zh)
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J·P·肯普夫
P·麦克菲森
D·查尔芬
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Smart Medicine Co ltd
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Smart Medicine Co ltd
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Priority to CN202111365747.3A priority Critical patent/CN114088950A/zh
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/521—Chemokines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/56—Staging of a disease; Further complications associated with the disease

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CN201880012782.7A 2017-01-12 2018-01-12 基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物 Pending CN110651187A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202111365747.3A CN114088950A (zh) 2017-01-12 2018-01-12 基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物

Applications Claiming Priority (3)

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US201762445692P 2017-01-12 2017-01-12
US62/445,692 2017-01-12
PCT/US2018/013561 WO2018132702A1 (en) 2017-01-12 2018-01-12 Methods and compositions for evaluation and treatment of renal injury and renal failure based on c-c motif chemokine ligand 14 measurement

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CN202111365747.3A Division CN114088950A (zh) 2017-01-12 2018-01-12 基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物

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CN110651187A true CN110651187A (zh) 2020-01-03

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CN202111365747.3A Pending CN114088950A (zh) 2017-01-12 2018-01-12 基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物

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US (2) US11353465B2 (enExample)
EP (2) EP4063853A1 (enExample)
JP (2) JP2020504157A (enExample)
CN (2) CN110651187A (enExample)
AU (1) AU2018207151B2 (enExample)
CA (1) CA3049444A1 (enExample)
MX (1) MX2019008260A (enExample)
WO (1) WO2018132702A1 (enExample)

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EP4063853A1 (en) * 2017-01-12 2022-09-28 Astute Medical, Inc. Methods and compositions for evaluation and treatment of renal injury and renal failure based on c-c motif chemokine ligand 14 measurement
EP3732196A4 (en) 2017-12-28 2022-01-05 Astute Medical, Inc. ANTIBODIES AND ASSAYS FOR CCL14
US20220236285A1 (en) * 2019-05-24 2022-07-28 Astute Medical, Inc. Methods for evaluation and treatment of renal injury based on c-c motif chemokine ligand 14 measurement
AU2020300544B2 (en) * 2019-07-02 2024-07-25 Astute Medical, Inc Antibodies and assays for CCL14
AU2021381364A1 (en) * 2020-11-18 2023-06-22 Astute Medical, Inc. Methods and compositions for treatment of renal injury and renal failure
CN113555122B (zh) * 2021-07-21 2024-04-26 中南大学湘雅二医院 一种重症脓毒症患者一过性和持续性aki的预测模型及其构建方法
AU2023229375A1 (en) * 2022-03-03 2024-09-12 Astute Medical, Inc. Methods and compositions for assessing and treating persistent acute kidney injury based on c-c motif chemokine ligand 14 measurement

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US11353465B2 (en) 2022-06-07
EP4063853A1 (en) 2022-09-28
JP2022091846A (ja) 2022-06-21
US20230025225A1 (en) 2023-01-26
US20190339289A1 (en) 2019-11-07
CA3049444A1 (en) 2018-07-19
US12203944B2 (en) 2025-01-21
EP3568695A4 (en) 2020-12-16
EP3568695A1 (en) 2019-11-20
AU2018207151A1 (en) 2019-07-18
AU2018207151B2 (en) 2024-02-29
MX2019008260A (es) 2020-01-27
WO2018132702A1 (en) 2018-07-19
CN114088950A (zh) 2022-02-25
JP2020504157A (ja) 2020-02-06

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