CN110646613A - Prostate cancer detection kit based on liquid biopsy - Google Patents
Prostate cancer detection kit based on liquid biopsy Download PDFInfo
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- CN110646613A CN110646613A CN201910896406.5A CN201910896406A CN110646613A CN 110646613 A CN110646613 A CN 110646613A CN 201910896406 A CN201910896406 A CN 201910896406A CN 110646613 A CN110646613 A CN 110646613A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
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Abstract
The invention discloses a prostate cancer detection kit based on liquid biopsy, which comprises a box body, wherein an inner box for bearing a biopsy specimen is arranged in the box body, the inner box is fixedly arranged on a supporting plate of the box body, the top of the inner box is correspondingly provided with a sealing cover for sealing, the bottom of the inner box is provided with an ice bag which corresponds in shape and wraps the bottom of the inner box, the bottom of the box body is provided with a lower sealing cover in threaded sealing connection, the box body is provided with a locking type data card packaging top cover for avoiding confusion, the inner box adopts a large-caliber design and is convenient for placing or taking out a sample, the bottom of the inner box is provided with the ice bag which corresponds in shape, the whole box body is placed in a refrigerator, so that the temperature of the ice bag is consistent with the temperature in the refrigerator, the low-temperature state of the inner box can be kept for a long time when the kit is used, the sample is favorably stored, meanwhile, a fixing liquid bearing bag is, the sample inside is convenient for preserve and fix, improves the save time of sample greatly.
Description
Technical Field
The invention relates to the technical field of kits, in particular to a kit for detecting prostate cancer based on liquid biopsy.
Background
Biopsy is called biopsy for short, and is called biopsy (biopsy) in general, and is also called surgical pathology examination, and is called external examination for short; this refers to a technique for taking out a diseased tissue from a patient by incision, forceps, puncture, or the like, and performing pathological examination, as required for diagnosis and treatment. When the prostate cancer biopsy sample is stored, in order to prevent the tissue from autolysis and putrefaction, the sample should be fixed in time after being taken. The specimen is preferably fixed by 10% formaldehyde (formalin), the amount of the fixing liquid is more than 5 times of the volume of the specimen to be detected, and the container for holding the specimen is large enough to keep the original shape of the specimen, and is large enough to facilitate the loading and the taking out of the specimen. Labeling the outside of the container: the name, sex, specimen name, hospital number, hospital bed number, etc. of the patient. When the samples are inspected frequently, the samples are not mixed, and a pathological submission application form is carefully filled item by item according to requirements, but the existing box body cannot meet the requirements.
Disclosure of Invention
The present invention aims to provide a kit for prostate cancer detection based on liquid biopsy, so as to solve the problems in the background art.
The purpose of the invention is realized by the following technical scheme: the utility model provides a kit that prostate cancer detected based on liquid biopsy, includes the box body, be equipped with the interior box that is used for holding biopsy specimen in the box body, interior box fixed mounting is in the backup pad of box body, and the top correspondence is equipped with the sealed lid of sealed sealing, and the bottom of interior box is equipped with the ice bag that the shape corresponds and will interior bottom of the box portion parcel, the bottom of box body is equipped with screw thread sealing connection's lower closing cap, be equipped with the sealed piece that improves the leakproofness and support the ice bag down on the closing cap, the top of box body also corresponds the top cap that is equipped with screw thread sealing connection, the top of top cap is equipped with the card encapsulation groove through transparent closing cap encapsulation data card.
Furthermore, a plurality of clamping blocks are arranged in the card packaging groove of the top cover, clamping grooves are formed in the clamping blocks and the edges of the card packaging groove, the data cards after being filled are placed in the middle of the card packaging groove, the transparent sealing cover is installed in the clamping grooves and used for sealing the data cards, the edges of the transparent sealing cover are designed in an outward protruding mode, and meanwhile elastic clamping strips capable of achieving locking type packaging are correspondingly arranged at the packaging positions of the clamping blocks and the transparent sealing cover.
Furthermore, the sealing cover is formed by combining a sealing piece and a sealing cover, a pressing groove is formed in the sealing cover, the barbed nail sleeved with the spring penetrates through the bottom of the pressing groove and is installed in the pressing groove through being connected with the limiting piece, the sharp thorn of the barbed nail is right opposite to the liquid leakage opening in the bottom, and a fixed liquid bearing bag installed in the sealing piece is correspondingly arranged between the liquid leakage opening and the barbed nail.
Furthermore, the fixing liquid bearing bag is made of an inelastic plastic bag, is integrally of a bowl-shaped structure corresponding to the position of the inner cavity of the sealing piece, and is filled with the specimen fixing liquid and inflated.
Furthermore, the limiting part is in threaded connection with the barbed nail, and a sealing gasket is correspondingly arranged at the contact position of the limiting part and the sealing cover.
Compared with the prior art, the novel liquid biopsy-based prostate cancer detection kit has the beneficial effects that the novel liquid biopsy-based prostate cancer detection kit is provided with the locking type data card packaging top cover to avoid confusion, the inner box is designed to be large-caliber to facilitate the placement or the taking out of a sample, the bottom of the inner box is provided with the ice bag with the corresponding shape, the whole box body is placed in a refrigerator, the temperature of the ice bag is kept consistent with the temperature in the refrigerator, the low-temperature state of the inner box can be kept for a long time during use, the sample can be stored conveniently, a fixing liquid containing bag is arranged, the fixing liquid can automatically flow into the inner box by pressing a puncture nail, the sample in the inner box can be stored and fixed conveniently, and the storage time of the sample is greatly prolonged.
Drawings
FIG. 1 is an overall block diagram of a kit for liquid biopsy-based prostate cancer detection according to the present invention;
FIG. 2 is an enlarged view of a partial view A of a kit for liquid biopsy based prostate cancer detection according to the present invention;
FIG. 3 is a block diagram of a sealing lid of a kit for liquid biopsy based prostate cancer detection according to the present invention;
in the figure: 1. top cap, 11, transparent closing cap, 12, data card, 13, fixture block, 14, elasticity card strip, 2, box body, 3, interior box, 4, lower closing cap, 41, sealed piece, 5, ice bag, 6, sealed lid, 61, weeping mouth, 62, stationary liquid holds bagging-off, 63, closing cap, 64, thorn nail, 65, spring, 66, locating part, 67, pressing groove.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and all other embodiments obtained by a person of ordinary skill in the art without creative efforts based on the embodiments of the present invention belong to the protection scope of the present invention.
As shown in fig. 1-3, the present invention discloses a prostate cancer detection kit based on liquid biopsy, which includes a box body 2, an inner box 3 for containing a biopsy specimen is arranged in the box body 2, the inner box 3 is fixedly mounted on a support plate of the box body 2, a sealing cover 6 for sealing and sealing is correspondingly arranged on the top of the inner box 3, an ice bag 5 which is corresponding in shape and wraps the bottom of the inner box 3 is arranged at the bottom of the inner box 3, a lower sealing cover 4 which is in threaded sealing connection is arranged at the bottom of the box body 2, a sealing block 41 for improving sealing and supporting the ice bag 5 is arranged on the lower sealing cover 4, a top cover 1 which is in threaded sealing connection is also correspondingly arranged at the top of the box body 2, and a card packaging groove for packaging a data card 12 through a transparent sealing cover 11 is arranged at the top of the.
The card packaging groove of the top cover 1 is internally provided with a plurality of clamping blocks 13, the clamping blocks 13 and the edge of the card packaging groove form a clamping groove, a filled data card 12 is placed in the middle of the card packaging groove, the transparent sealing cover 11 is installed in the clamping groove and used for sealing the data card 12, the edge of the transparent sealing cover 11 is designed in an outward protruding mode, and meanwhile, the clamping blocks 13 and the packaging position of the transparent sealing cover 11 are correspondingly provided with elastic clamping strips 14 capable of achieving locking type packaging.
The sealing cover 6 is formed by combining a sealing piece and a sealing cover 63, a pressing groove 67 is formed in the sealing cover 63, a spike 64 sleeved with a spring 65 penetrates through the bottom of the pressing groove 67 and is installed in the pressing groove 67 through being connected with a limiting piece 66, a spike of the spike 64 just faces a liquid leakage opening 61 in the bottom, and a fixed liquid bearing bag 62 installed in the sealing piece is correspondingly arranged between the liquid leakage opening 61 and the spike 64.
The fixing liquid bearing bag 62 is made of an inelastic plastic bag, is of a bowl-type structure corresponding to the position of the inner cavity of the sealing piece as a whole, is filled with the specimen fixing liquid and is inflated, and after being punctured by the puncture nails 64, the liquid inside can automatically flow into the inner box 3 under the action of gas, so that the specimen fixing effect is achieved.
The limiting member 66 is in threaded connection with the spike 64, and a sealing gasket is correspondingly arranged at the contact position of the limiting member 66 and the sealing cover 63, so that the limiting member 66 can be tightly attached to the sealing cover 63 under the action of the spring 65, and the sealing performance is ensured.
The novel prostate cancer detection kit based on liquid biopsy has the advantages that the novel prostate cancer detection kit based on liquid biopsy is provided with the locking type data card packaging top cover, confusion is avoided, the inner box is designed to be large-caliber, samples can be placed or taken out conveniently, the ice bag with the corresponding shape is arranged at the bottom, the whole box body is placed in a refrigerator, the temperature of the ice bag is enabled to be consistent with the temperature in the refrigerator, the low-temperature state of the inner box can be kept for a long time when the kit is used, the samples can be stored conveniently, meanwhile, the fixing liquid containing bag is arranged, the fixing liquid can automatically flow into the inner box through pressing of the barbed nails, the samples in the inner box can be stored and fixed conveniently, and the storage time of the samples is greatly prolonged.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (4)
1. A kit for prostate cancer detection based on liquid biopsy, comprising a cartridge (2), characterized in that: an inner box (3) used for containing biopsy samples is arranged in the box body (2), the inner box (3) is fixedly arranged on a supporting plate of the box body (2), a sealing cover (6) for sealing and sealing is correspondingly arranged at the top of the inner box (3), an ice bag (5) which corresponds in shape and wraps the bottom of the inner box (3) is arranged at the bottom of the inner box (3), a lower sealing cover (4) which is in threaded sealing connection is arranged at the bottom of the box body (2), a sealing block (41) which improves the sealing performance and supports the ice bag (5) is arranged on the lower sealing cover (4), a top cover (1) which is in threaded sealing connection is also correspondingly arranged at the top of the box body (2), and a card packaging groove for packaging data cards (12) through a transparent sealing cover (11) is arranged at the top of the top cover (;
the card packaging groove of top cap (1) is equipped with a plurality of fixture blocks (13), each fixture block (13) and the edge in card packaging groove form the buckle groove, and data card (12) after filling in are placed in card packaging groove middle part, and transparent closing cap (11) are installed in the buckle inslot to with data card (12) seal in, the edge of transparent closing cap (11) adopts the design of evagination formula, and each fixture block (13) corresponds with transparent closing cap (11) encapsulation department and is equipped with elasticity card strip (14) that can realize the closure formula encapsulation simultaneously.
2. The kit for liquid biopsy based prostate cancer detection according to claim 1, wherein: the sealing cover (6) is formed by combining a sealing piece and a sealing cover (63), a pressing groove (67) is formed in the sealing cover (63), a spike nail (64) sleeved with a spring (65) penetrates through the bottom of the pressing groove (67) and is installed in the pressing groove (67) through being connected with a limiting piece (66), a spike of the spike nail (64) is right opposite to a liquid leakage opening (61) in the bottom, and a fixed liquid bearing bag (62) installed in the sealing piece is correspondingly arranged between the liquid leakage opening (61) and the spike nail (64).
3. The kit for liquid biopsy based prostate cancer detection according to claim 2, wherein: the fixing liquid bearing bag (62) is made of an inelastic plastic bag, is of a bowl-shaped structure corresponding to the position of the inner cavity of the sealing piece as a whole, and is filled with the specimen fixing liquid and inflated.
4. The kit for liquid biopsy based prostate cancer detection according to claim 3, wherein: the limiting piece (66) is in threaded connection with the barbed nail (64), and a sealing gasket is correspondingly arranged at the contact position of the limiting piece (66) and the sealing cover (63).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910896406.5A CN110646613A (en) | 2019-09-20 | 2019-09-20 | Prostate cancer detection kit based on liquid biopsy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910896406.5A CN110646613A (en) | 2019-09-20 | 2019-09-20 | Prostate cancer detection kit based on liquid biopsy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110646613A true CN110646613A (en) | 2020-01-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910896406.5A Withdrawn CN110646613A (en) | 2019-09-20 | 2019-09-20 | Prostate cancer detection kit based on liquid biopsy |
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| CN (1) | CN110646613A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112098182A (en) * | 2020-08-31 | 2020-12-18 | 中国科学院水生生物研究所 | Deep sea biological sample normal position chemistry fixing device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112098182A (en) * | 2020-08-31 | 2020-12-18 | 中国科学院水生生物研究所 | Deep sea biological sample normal position chemistry fixing device |
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Application publication date: 20200103 |