CN110628595A - Wireless ultrasonic real-time monitoring microbial fermentation device - Google Patents
Wireless ultrasonic real-time monitoring microbial fermentation device Download PDFInfo
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- CN110628595A CN110628595A CN201910893848.4A CN201910893848A CN110628595A CN 110628595 A CN110628595 A CN 110628595A CN 201910893848 A CN201910893848 A CN 201910893848A CN 110628595 A CN110628595 A CN 110628595A
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- 238000000855 fermentation Methods 0.000 title claims abstract description 105
- 230000004151 fermentation Effects 0.000 title claims abstract description 105
- 230000000813 microbial effect Effects 0.000 title claims abstract description 26
- 238000012544 monitoring process Methods 0.000 title claims abstract description 26
- 239000000523 sample Substances 0.000 claims abstract description 85
- 230000005540 biological transmission Effects 0.000 claims description 15
- 239000013078 crystal Substances 0.000 claims description 14
- 244000005700 microbiome Species 0.000 claims description 11
- 238000006243 chemical reaction Methods 0.000 claims description 6
- 238000010521 absorption reaction Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 229910052593 corundum Inorganic materials 0.000 claims description 4
- 239000010431 corundum Substances 0.000 claims description 4
- 239000010963 304 stainless steel Substances 0.000 claims description 3
- 229910000589 SAE 304 stainless steel Inorganic materials 0.000 claims description 3
- 238000004140 cleaning Methods 0.000 claims description 3
- 238000009434 installation Methods 0.000 claims description 3
- 238000005507 spraying Methods 0.000 claims description 3
- 238000003384 imaging method Methods 0.000 abstract 1
- 241001052560 Thallis Species 0.000 description 8
- 241000894006 Bacteria Species 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000002159 abnormal effect Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000002604 ultrasonography Methods 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Treatment Of Sludge (AREA)
Abstract
The invention discloses a wireless ultrasonic real-time monitoring microbial fermentation device which comprises a fermentation tank, wherein a tank cover is hinged to the top of the fermentation tank, and a discharge valve is arranged at the bottom of the fermentation tank; the wireless ultrasonic probe is arranged on the outer wall of the fermentation tank and is used for detecting a fermented product in the fermentation tank and acquiring a signal; the controller controls the pushing mechanism to act to drive the wireless ultrasonic probe to move on the outer wall of the fermentation tank; the wireless ultrasonic probe is in signal connection with the controller and displays the signals acquired by the wireless ultrasonic probe through the display screen image of the controller. According to the invention, the two wireless ultrasonic probes are arranged on the outer wall of the fermentation tank, the fermentation condition of microbial cells in the fermentation tank is monitored in real time by adopting an ultrasonic imaging technology, and the two wireless ultrasonic probes can move on the outer wall of the fermentation tank through the pushing mechanism, so that the monitoring area of the wireless ultrasonic probes is increased.
Description
Technical Field
The invention relates to the technical field of microbial fermentation, in particular to a wireless ultrasonic real-time monitoring microbial fermentation device.
Background
Microbial fermentation is a major process in current biopharmaceutical processes, in industrial processes microbial fermentation is performed in large fermenters, and fermentation times typically vary from days to weeks. In the fermentation process, the liquid in the fermentation tank needs to be checked and analyzed regularly to ensure that the fermentation process is normal and find problems such as abnormal growth of fermentation thalli, mixed bacteria pollution in the fermentation process and the like in time. In the prior art, a sensor is arranged in a fermentation tank to monitor parameters such as temperature, dissolved oxygen rate and the like, and a method of extracting fermentation liquor periodically and analyzing the fermentation liquor is combined to monitor the fermentation process. However, if an abnormal condition such as contamination with bacteria is found, it is often too late to take effective measures to remedy the abnormal condition. The reason is that the fermentation device is mainly lack of suitable and effective online real-time monitoring for some important parameters, so that the fermentation device capable of visually monitoring the fermentation condition of the microorganisms in real time is urgently needed to be provided.
Disclosure of Invention
The purpose of this patent is in order to provide a can real time monitoring fermenting installation inside microorganism fermentation condition to can realize the inside visualization of fermenting installation.
In order to achieve the purpose, the following technical scheme is adopted in the patent:
a wireless ultrasonic real-time monitoring microbial fermentation device comprises:
the fermentation tank is hinged with a tank cover at the top and provided with a discharge valve at the bottom;
the wireless ultrasonic probe is arranged on the outer wall of the fermentation tank and is used for detecting a fermented product in the fermentation tank and acquiring a signal;
the controller controls the pushing mechanism to act to drive the wireless ultrasonic probe to move on the outer wall of the fermentation tank;
the wireless ultrasonic probe is in signal connection with the controller and displays the signals acquired by the wireless ultrasonic probe through the display screen image of the controller.
Preferably, the pushing mechanism comprises a rack, a stepping motor and a gear;
the step motor is controlled by the controller, the step motor is fixedly arranged on the outer wall of the fermentation tank, and the gear is fixedly connected with a rotating shaft of the step motor and is rotatably arranged on a gear shaft lever fixing frame on the outer wall of the fermentation tank through a gear shaft lever;
and a rack sliding rail is axially arranged on the outer wall of the fermentation tank along the axial direction, the rack is positioned in the rack sliding rail and is connected with the rack sliding rail in a sliding fit manner, and the rack is meshed with the gear.
Preferably, the number of the wireless ultrasonic probes is two, the two wireless ultrasonic probes are respectively installed on two sides of the bottom of the rack, an ultrasonic probe sliding groove is further formed in the position, corresponding to the wireless ultrasonic probes, on the outer wall of the fermentation tank, and the wireless ultrasonic probes are located in the ultrasonic probe sliding grooves and can slide in the ultrasonic probe sliding grooves.
Preferably, a plurality of rack stop bars are erected on the rack slide rail at intervals.
Preferably, the wireless ultrasonic probe comprises a probe part, an analog-to-digital conversion module, a control module and a wireless transmission transceiving module;
the control module of the wireless ultrasonic probe is in signal connection with the controller and is used for controlling the probe to partially act to send out ultrasonic waves and collecting signals for microorganisms in the fermentation tank by utilizing the ultrasonic waves;
the analog-to-digital conversion module is electrically connected with the probe part and converts analog signals acquired by the probe part into digital signals;
the wireless transmission transceiver module is controlled by the control module to transmit the digital signal to the controller.
Preferably, the probe part is provided with a piezoelectric crystal, the front surface of the piezoelectric crystal is pasted with a matching layer, the matching layer adopts stainless steel or corundum, and the back surface is filled with a sound absorption material.
Preferably, the controller further comprises a controller wireless transmission transceiver module, and the controller wireless transmission transceiver module is connected with the wireless transmission transceiver module of the wireless ultrasonic probe through WIFI.
Preferably, the bottom of the fermentation tank is also connected with a bracket.
Preferably, the interior of the fermenter is provided with a spray system for cleaning the microorganisms.
The invention has the beneficial effects that:
the two wireless ultrasonic probes can work simultaneously and independently and can be switched at any time when the two wireless ultrasonic probes operate independently, so that the two wireless ultrasonic probes can be conveniently and visually observed by people, the two wireless ultrasonic probes can also move on the outer wall of the fermentation tank through the pushing mechanism, the monitoring area of the wireless ultrasonic probes is increased, the pushing mechanism controls the meshing transmission of the gear and the rack by adopting the stepping motor, the wireless ultrasonic probes are driven to move, the pushing distance and the pushing speed can be adjusted according to the number of rotating turns of the stepping motor, the moving speed of the linear ultrasonic probes is uniform and proper, and the image display is ensured to be clear.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:
FIG. 1 is a schematic structural diagram of a wireless ultrasonic real-time monitoring microbial fermentation apparatus according to the present invention;
FIG. 2 is a schematic view of a partial structure of a wireless ultrasonic real-time monitoring microbial fermentation apparatus according to the present invention;
FIG. 3 is a structural diagram of the assembly of a stepping motor and a rack of the wireless ultrasonic real-time monitoring microbial fermentation device according to the present invention;
FIG. 4 is a control system diagram of the wireless ultrasonic probe and the controller of the wireless ultrasonic real-time monitoring microbial fermentation device provided by the invention.
In the figure: 1. a fermentation tank; 2. a can lid; 3. a support; 4. a discharge valve; 5. a rack slide rail; 6. a rack; 7. a rack bar; 8. an ultrasonic probe chute; 9. a stepping motor; 10. a gear shaft lever fixing frame; 11. a gear; 12. a gear shaft lever; 13. a wireless ultrasound probe; 14. and a controller.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are illustrative and intended to be illustrative of the invention and are not to be construed as limiting the invention.
In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the invention and to simplify the description, and are not intended to indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and are therefore not to be considered limiting of the invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
Referring to fig. 1-4, the wireless ultrasonic real-time monitoring microbial fermentation device comprises a fermentation tank 1, wherein a tank cover 2 is hinged to the top of the fermentation tank 1, and a discharge valve 4 is arranged at the bottom of the fermentation tank 1;
the wireless ultrasonic probe 13 is arranged on the outer wall of the fermentation tank 1, and is used for detecting the fermentation product in the fermentation tank 1 and acquiring signals;
the controller 14 controls the pushing mechanism to act to drive the wireless ultrasonic probe 13 to move on the outer wall of the fermentation tank 1;
the wireless ultrasonic probe 13 is in signal connection with the controller 14, and the signals acquired by the wireless ultrasonic probe 13 are displayed through the display screen image of the controller 14, in the invention, the controller 14 is used for controlling the wireless ultrasonic probe 13 to detect the fermentation product in the fermentation tank 1, and the detected signals are transmitted to the display screen on the controller 14 for display after being processed, so that the fermentation condition of the bacteria in the fermentation tank 1 can be conveniently and visually seen by personnel.
As a further improvement of the invention, the pushing mechanism comprises a rack 6, a stepping motor 9 and a gear 11;
the stepping motor 9 is controlled by the controller 14, the number of turns and the rotating speed of the stepping motor can be adjusted by the controller 14, the stepping motor 9 is fixedly arranged on the outer wall of the fermentation tank 1, and the gear 11 is fixedly connected with the rotating shaft of the stepping motor 9 and is rotatably arranged on a gear shaft rod fixing frame 10 on the outer wall of the fermentation tank 1 through a gear shaft rod 12;
the outer wall of the fermentation tank 1 is provided with a rack slide rail 5 along the axial direction, a rack 6 is positioned in the rack slide rail 5 and is connected with the rack slide rail in a sliding fit manner, the rack 6 is meshed with a gear 11, when the pushing mechanism acts, a stepping motor 9 rotates to drive the gear 11 to synchronously rotate, the gear 11 is meshed with the rack 6 installed in the rack slide rail 5, and the rack 6 can linearly move along with the rotation of the gear 11.
As a preferred embodiment, two wireless ultrasonic probes 13 are provided, the two wireless ultrasonic probes 13 are respectively installed on two sides of the bottom of the rack 6, and the two wireless ultrasonic probes 13 can work simultaneously, and also can run singly and can realize switching between the two, so that personnel can observe the fermentation conditions of thalli at different positions in real time, an ultrasonic probe chute 8 is further arranged at a position on the outer wall of the fermentation tank 1 corresponding to the wireless ultrasonic probes 13, the wireless ultrasonic probes 13 are located in the ultrasonic probe chute 8 and can slide in the ultrasonic probe chute 8, the wireless ultrasonic probes 13 are lifted along with the movement of the rack 6, and the monitoring area of thalli in the fermentation tank 1 is effectively increased.
As a preferred embodiment, a plurality of rack bars 7 are arranged on the rack slide rail 5 at intervals, and the rack bars 7 can prevent the rack 6 from warping in the operation process.
As a preferred embodiment, the wireless ultrasound probe 13 includes a probe part, an analog-to-digital conversion module, a control module and a wireless transmission transceiver module;
the control module of the wireless ultrasonic probe 13 is in signal connection with the controller 14 and is used for controlling the probe to act to emit ultrasonic waves, the ultrasonic waves are used for collecting signals of microorganisms in the fermentation tank 1, high-frequency electric signals emitted by the probe are converted into the ultrasonic waves through the vibration of the crystal and are emitted to thalli in the fermentation tank 1, the ultrasonic waves emitted by the thalli are converted into the high-frequency electric signals through the crystal again, and therefore information collection of the fermentation condition of the thalli is achieved; the analog-to-digital conversion module is electrically connected with the probe part and converts analog signals acquired by the probe part into digital signals; the wireless transceiver module is controlled by the control module to transmit the digital signal to the controller 14.
Specifically, the probe part of the wireless ultrasonic probe 13 is provided with a piezoelectric crystal, the piezoelectric crystal generates vibration when being excited by electric pulses to generate ultrasonic waves, the ultrasonic waves are reflected by bacteria and then act on the crystal, the vibration deformation of the crystal is converted into corresponding electric signals, a matching layer is attached to the front side of the piezoelectric crystal, the matching layer is made of 304 stainless steel or corundum, the 304 stainless steel or corundum can protect the piezoelectric crystal, the acoustic resistance difference between the piezoelectric crystal and the outer wall of the fermentation tank 1 can be enabled to be close, the back side of the piezoelectric crystal is filled with a sound absorption material, the sound absorption material can generate short ultrasonic pulse signals, and the longitudinal resolution capability of the sound absorption material.
As a preferred embodiment, the controller 14 further includes a controller wireless transmission transceiver module, the controller wireless transmission transceiver module is connected with the wireless transmission transceiver module of the wireless ultrasound probe 13 through WIFI, and the whole signal is transmitted and received in a WIFI manner, so that the trouble of network wiring can be avoided.
As a preferred embodiment, the bottom of the fermentation tank 1 is also connected with a bracket 3, and the fermentation tank 1 is stably placed at a working site through the bracket 3 to provide a safe working environment for the fermentation of microorganisms.
In a preferred embodiment, a spraying system for cleaning microorganisms is provided inside the fermentation tank 1, after the fermentation of the microorganisms is completed, the discharge valve 4 is opened to take out the fermented thalli, and then the inside of the fermentation tank 1 is cleaned in all directions by the spraying system, so that the next fermentation operation can be facilitated.
When the wireless ultrasonic real-time monitoring microbial fermentation device works, the tank cover 2 is opened, microbes are poured into the fermentation tank 1, the tank cover 2 is sealed, environmental parameters in the fermentation tank 1 are set to be numerical values required by microbial fermentation, the microbes start to ferment, in the fermentation process, a person can drive the stepping motor 9 to work through the controller 14, the stepping motor 9 rotates to drive the rack 6 to vertically move along the outer wall of the fermentation tank 1, so that the two wireless ultrasonic probes 13 at the bottom of the rack 6 move simultaneously, meanwhile, the person drives the wireless ultrasonic probes 13 to work through control buttons on an operation panel of the operation controller 14, the wireless ultrasonic probes 13 send ultrasonic microbial cells, ultrasonic waves are transmitted and then return to the wireless ultrasonic probes 13 to finish information acquisition of the microbial cells, and information acquired by the wireless ultrasonic probes 13 is transmitted to the controller 14 in a WIFI mode after being processed, the signals acquired by the wireless ultrasonic probe 13 are displayed on a display screen of the controller 14 in a real-time image mode, so that the fermentation condition of the thalli in the fermentation tank 1 can be monitored by the staff in real time.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be able to cover the technical scope of the present invention and the equivalent alternatives or modifications according to the technical solution and the inventive concept of the present invention within the technical scope of the present invention.
Claims (9)
1. Wireless supersound real time monitoring microorganism fermenting installation, its characterized in that includes:
the fermentation tank is hinged with a tank cover at the top and provided with a discharge valve at the bottom;
the wireless ultrasonic probe is arranged on the outer wall of the fermentation tank and is used for detecting a fermented product in the fermentation tank and acquiring a signal;
the controller controls the pushing mechanism to act to drive the wireless ultrasonic probe to move on the outer wall of the fermentation tank;
the wireless ultrasonic probe is in signal connection with the controller and displays the signals acquired by the wireless ultrasonic probe through the display screen image of the controller.
2. The wireless ultrasonic real-time monitoring microbial fermentation device of claim 1, wherein: the pushing mechanism comprises a rack, a stepping motor and a gear;
the step motor is controlled by the controller, the step motor is fixedly arranged on the outer wall of the fermentation tank, and the gear is fixedly connected with a rotating shaft of the step motor and is rotatably arranged on a gear shaft lever fixing frame on the outer wall of the fermentation tank through a gear shaft lever;
and a rack sliding rail is axially arranged on the outer wall of the fermentation tank along the axial direction, the rack is positioned in the rack sliding rail and is connected with the rack sliding rail in a sliding fit manner, and the rack is meshed with the gear.
3. The wireless ultrasonic real-time monitoring microbial fermentation device of claim 2, wherein: the fermentation tank is characterized in that the number of the wireless ultrasonic probes is two, the two wireless ultrasonic probes are respectively arranged on two sides of the bottom of the rack, an ultrasonic probe sliding groove is further formed in the outer wall of the fermentation tank at a position corresponding to the wireless ultrasonic probes, and the wireless ultrasonic probes are located in the ultrasonic probe sliding grooves and can slide in the ultrasonic probe sliding grooves.
4. The wireless ultrasonic real-time monitoring microbial fermentation device of claim 2, wherein: a plurality of rack stop bars are erected on the rack slide rails at intervals.
5. The wireless ultrasonic real-time monitoring microbial fermentation device of claim 1, wherein: the wireless ultrasonic probe comprises a probe part, an analog-to-digital conversion module, a control module and a wireless transmission transceiving module;
the control module of the wireless ultrasonic probe is in signal connection with the controller and is used for controlling the probe to partially act to send out ultrasonic waves and collecting signals for microorganisms in the fermentation tank by utilizing the ultrasonic waves;
the analog-to-digital conversion module is electrically connected with the probe part and converts analog signals acquired by the probe part into digital signals;
the wireless transmission transceiver module is controlled by the control module to transmit the digital signal to the controller.
6. The wireless ultrasonic real-time monitoring microbial fermentation device of claim 5, wherein: the probe part is provided with a piezoelectric crystal, the front surface of the piezoelectric crystal is pasted with a matching layer, the matching layer adopts 304 stainless steel or corundum, and the back surface is filled with sound absorption materials.
7. The wireless ultrasonic real-time monitoring microbial fermentation device of claim 5, wherein: the controller also comprises a controller wireless transmission transceiver module, and the controller wireless transmission transceiver module is connected with the wireless transmission transceiver module of the wireless ultrasonic probe through WIFI.
8. The wireless ultrasonic real-time monitoring microbial fermentation device of claim 1, wherein: the bottom of the fermentation tank is also connected with a bracket.
9. The wireless ultrasonic real-time monitoring microbial fermentation device of claim 1, wherein: and a spraying system for cleaning microorganisms is arranged in the fermentation tank.
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CN201910893848.4A CN110628595A (en) | 2019-09-20 | 2019-09-20 | Wireless ultrasonic real-time monitoring microbial fermentation device |
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Citations (6)
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US20040106170A1 (en) * | 2001-03-08 | 2004-06-03 | Anna Kornfeldt | Method and device for monitoring and controlling a process |
CN101349676A (en) * | 2007-07-18 | 2009-01-21 | 宁波大学 | Apparatus and method for monitoring small molecule and life macromolecule interaction by ultrasonic wave |
US20100206079A1 (en) * | 2007-04-13 | 2010-08-19 | Bioinnovel Limited | Ultrasonic monitor for a bioreactor |
CN102839122A (en) * | 2012-06-29 | 2012-12-26 | 上海杰穆实业有限公司 | Real-time monitoring system of a microbial fermentation process |
CN206521475U (en) * | 2016-10-27 | 2017-09-26 | 威德环境科技股份有限公司 | Anaerobic fermentation experimental rig |
CN206956041U (en) * | 2017-05-27 | 2018-02-02 | 西安青苗生物科技有限公司 | The biological fermentation tank of monitoring course of fermentation in real time |
-
2019
- 2019-09-20 CN CN201910893848.4A patent/CN110628595A/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040106170A1 (en) * | 2001-03-08 | 2004-06-03 | Anna Kornfeldt | Method and device for monitoring and controlling a process |
US20100206079A1 (en) * | 2007-04-13 | 2010-08-19 | Bioinnovel Limited | Ultrasonic monitor for a bioreactor |
CN101349676A (en) * | 2007-07-18 | 2009-01-21 | 宁波大学 | Apparatus and method for monitoring small molecule and life macromolecule interaction by ultrasonic wave |
CN102839122A (en) * | 2012-06-29 | 2012-12-26 | 上海杰穆实业有限公司 | Real-time monitoring system of a microbial fermentation process |
CN206521475U (en) * | 2016-10-27 | 2017-09-26 | 威德环境科技股份有限公司 | Anaerobic fermentation experimental rig |
CN206956041U (en) * | 2017-05-27 | 2018-02-02 | 西安青苗生物科技有限公司 | The biological fermentation tank of monitoring course of fermentation in real time |
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