CN110623933B - Metformin hydrochloride controlled release tablet and preparation method thereof - Google Patents
Metformin hydrochloride controlled release tablet and preparation method thereof Download PDFInfo
- Publication number
- CN110623933B CN110623933B CN201910518648.0A CN201910518648A CN110623933B CN 110623933 B CN110623933 B CN 110623933B CN 201910518648 A CN201910518648 A CN 201910518648A CN 110623933 B CN110623933 B CN 110623933B
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- CN
- China
- Prior art keywords
- release
- tablet
- layer
- coating
- preparation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Abstract
Description
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910518648.0A CN110623933B (en) | 2019-06-15 | 2019-06-15 | Metformin hydrochloride controlled release tablet and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201910518648.0A CN110623933B (en) | 2019-06-15 | 2019-06-15 | Metformin hydrochloride controlled release tablet and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
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CN110623933A CN110623933A (en) | 2019-12-31 |
CN110623933B true CN110623933B (en) | 2022-07-01 |
Family
ID=68968863
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201910518648.0A Active CN110623933B (en) | 2019-06-15 | 2019-06-15 | Metformin hydrochloride controlled release tablet and preparation method thereof |
Country Status (1)
Country | Link |
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CN (1) | CN110623933B (en) |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6099862A (en) * | 1998-08-31 | 2000-08-08 | Andrx Corporation | Oral dosage form for the controlled release of a biguanide and sulfonylurea |
US6495162B2 (en) * | 1998-03-20 | 2002-12-17 | Andrx Pharmaceuticals, Inc. | Controlled release oral tablet having a unitary core |
CN101161242A (en) * | 2006-10-13 | 2008-04-16 | 北京红林制药有限公司 | A explosive core composition of controlled release administer drug and controlled release preparation as well as its preparing method |
CN102871982A (en) * | 2012-10-16 | 2013-01-16 | 中国科学院上海药物研究所 | Medicine osmotic pump preparation |
CN104940159A (en) * | 2015-07-15 | 2015-09-30 | 山东司邦得制药有限公司 | Metformin hydrochloride sustained-release tablet and preparing method and application thereof |
CN105232490A (en) * | 2015-11-11 | 2016-01-13 | 青岛百洋制药有限公司 | Metformin hydrochloride sustained release tablet and preparation method thereof |
CN105878256A (en) * | 2015-01-05 | 2016-08-24 | 合肥立方制药股份有限公司 | Controlled-release preparation containing metformin hydrochloride and glimepiride and preparation method of controlled-release preparation |
CN105878204A (en) * | 2014-12-16 | 2016-08-24 | 合肥立方制药股份有限公司 | Metformin hydrochloride osmotic pump controlled release tablet and preparation method thereof |
CN107260697A (en) * | 2017-05-26 | 2017-10-20 | 合肥华方医药科技有限公司 | A kind of Metformin hydrochloride controlled release tablet and preparation method thereof |
CN108578380A (en) * | 2017-07-25 | 2018-09-28 | 广州玻思韬控释药业有限公司 | Controlled releasing penetrant pump |
-
2019
- 2019-06-15 CN CN201910518648.0A patent/CN110623933B/en active Active
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6495162B2 (en) * | 1998-03-20 | 2002-12-17 | Andrx Pharmaceuticals, Inc. | Controlled release oral tablet having a unitary core |
US6099862A (en) * | 1998-08-31 | 2000-08-08 | Andrx Corporation | Oral dosage form for the controlled release of a biguanide and sulfonylurea |
CN101161242A (en) * | 2006-10-13 | 2008-04-16 | 北京红林制药有限公司 | A explosive core composition of controlled release administer drug and controlled release preparation as well as its preparing method |
CN102871982A (en) * | 2012-10-16 | 2013-01-16 | 中国科学院上海药物研究所 | Medicine osmotic pump preparation |
CN105878204A (en) * | 2014-12-16 | 2016-08-24 | 合肥立方制药股份有限公司 | Metformin hydrochloride osmotic pump controlled release tablet and preparation method thereof |
CN105878256A (en) * | 2015-01-05 | 2016-08-24 | 合肥立方制药股份有限公司 | Controlled-release preparation containing metformin hydrochloride and glimepiride and preparation method of controlled-release preparation |
CN104940159A (en) * | 2015-07-15 | 2015-09-30 | 山东司邦得制药有限公司 | Metformin hydrochloride sustained-release tablet and preparing method and application thereof |
CN105232490A (en) * | 2015-11-11 | 2016-01-13 | 青岛百洋制药有限公司 | Metformin hydrochloride sustained release tablet and preparation method thereof |
CN107260697A (en) * | 2017-05-26 | 2017-10-20 | 合肥华方医药科技有限公司 | A kind of Metformin hydrochloride controlled release tablet and preparation method thereof |
CN108578380A (en) * | 2017-07-25 | 2018-09-28 | 广州玻思韬控释药业有限公司 | Controlled releasing penetrant pump |
Non-Patent Citations (2)
Title |
---|
口服渗透泵控释制剂的研究进展;安欣欣等;《中国药房》;20181231;第29卷(第22期);第3165-3168页 * |
盐酸二甲双胍渗透泵控释片的制备及体外释放度考察;尹飞等;《实用药物与临床》;20091231;第12卷(第3期);第194-196页 * |
Also Published As
Publication number | Publication date |
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CN110623933A (en) | 2019-12-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Bian Jiangang Inventor after: Li Chengwen Inventor after: Yin Lifang Inventor after: Liu Wei Inventor after: Ma Hao Inventor after: Kong Chenxi Inventor after: Liu Jing Inventor after: Zhang Huawei Inventor before: Bian Jiangang Inventor before: Li Chengwen Inventor before: Liu Wei Inventor before: Ma Hao Inventor before: Kong Chenxi Inventor before: Liu Jing Inventor before: Zhang Huawei |
|
CI02 | Correction of invention patent application | ||
CI02 | Correction of invention patent application |
Correction item: Inventor Correct: Bian Jiangang|Li Chengwen|Yin Lifang|Liu Wei|Ma Hao|Kong Chenxi|Liu Jing|Zhang Huawei False: Bian Jiangang|Li Chengwen|Yin Lifang|Liu Wei|Ma Hao|Kong Chenxi|Liu Jing|Zhang Huawei Number: 52-01 Volume: 36 |
|
GR01 | Patent grant | ||
GR01 | Patent grant |