CN110613626A - Toothpaste containing paeoniflorin - Google Patents

Toothpaste containing paeoniflorin Download PDF

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Publication number
CN110613626A
CN110613626A CN201910882088.7A CN201910882088A CN110613626A CN 110613626 A CN110613626 A CN 110613626A CN 201910882088 A CN201910882088 A CN 201910882088A CN 110613626 A CN110613626 A CN 110613626A
Authority
CN
China
Prior art keywords
parts
paeoniflorin
sodium
toothpaste containing
toothpaste
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910882088.7A
Other languages
Chinese (zh)
Inventor
韩亚伟
管丽红
陈丽平
李盼盼
韩润渠
韩晨炳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhengzhou University of Light Industry
Original Assignee
Zhengzhou University of Light Industry
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhengzhou University of Light Industry filed Critical Zhengzhou University of Light Industry
Priority to CN201910882088.7A priority Critical patent/CN110613626A/en
Publication of CN110613626A publication Critical patent/CN110613626A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24Phosphorous; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25Silicon; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/463Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Abstract

The invention relates to a toothpaste containing paeoniflorin, which comprises the following components in parts by weight: 35-50 parts of stone powder, 20-30 parts of sorbitol, 15-25 parts of deionized water, 1-3 parts of sodium dodecyl sulfate, 0.8-2 parts of essence, 0.5-2 parts of sodium monofluorophosphate, 0.3-1.5 parts of sodium carboxymethylcellulose, 0.3-1.5 parts of sodium silicate, 0.1-0.4 part of saccharin sodium, 0.1-0.4 part of trisodium phosphate, 0.1-0.3 part of monosodium phosphate and 0.03-0.1 part of paeoniflorin; the toothpaste containing paeoniflorin has the effects of inhibiting bacteria, diminishing inflammation, preventing gum diseases such as gum swelling and the like, has good effects on certain tooth and oral diseases, is simple in raw materials and processing method, low in production cost and suitable for mass production.

Description

Toothpaste containing paeoniflorin
Technical Field
The invention belongs to the technical field of daily products, and particularly relates to toothpaste containing paeoniflorin.
Background
The toothpaste is one of the necessary cleaning products in daily life, the main function of the common toothpaste is to clean teeth, but with the continuous progress of science and technology, various functional toothpastes are also brought out one after another for solving the health problems of different teeth and oral cavities, the quality and the efficacy of the toothpaste products are also continuously improved, the existing toothpaste variety is developed into multifunctional toothpastes with complete varieties, various functions and hundreds of brands from a single cleaning type toothpaste, and the consumption requirements of different levels are met.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide the toothpaste containing paeoniflorin, which has obvious effects of inhibiting bacteria, diminishing inflammation and preventing gingival bleeding and gingival swelling.
The technical scheme of the invention is as follows: a toothpaste containing paeoniflorin comprises the following components in parts by weight: 35-50 parts of stone powder, 20-30 parts of sorbitol, 15-25 parts of deionized water, 1-3 parts of sodium dodecyl sulfate, 0.8-2 parts of essence, 0.5-2 parts of sodium monofluorophosphate, 0.3-1.5 parts of sodium carboxymethylcellulose, 0.3-1.5 parts of sodium silicate, 0.1-0.4 part of saccharin sodium, 0.1-0.4 part of trisodium phosphate, 0.1-0.3 part of monosodium phosphate and 0.03-0.1 part of paeoniflorin.
Further, the toothpaste containing paeoniflorin comprises the following components in parts by weight: 48 parts of stone powder, 27 parts of sorbitol, 18 parts of deionized water, 2.5 parts of sodium dodecyl sulfate, 1.1 parts of essence, 1 part of sodium monofluorophosphate, 0.9 part of sodium carboxymethylcellulose, 0.8 part of sodium silicate, 0.25 part of saccharin sodium, 0.25 part of trisodium phosphate, 0.15 part of monosodium phosphate and 0.05 part of paeoniflorin.
Further, the paeoniflorin is extracted from peony.
Further, the purity of the paeoniflorin is 95%.
The invention has the beneficial effects that: the paeoniflorin is added into the functional components of the original toothpaste, so that the toothpaste has the effects of inhibiting bacteria, diminishing inflammation, preventing gum swelling and other gum diseases, and has a good effect on certain teeth and oral diseases due to the mutual cooperation of the components; in addition, the raw materials and the processing method are simple, the production cost is low, and the method is suitable for mass production.
Detailed Description
The present invention will be further described with reference to the following examples.
Example 1
A toothpaste containing paeoniflorin comprises the following components in parts by weight: 48 parts of stone powder, 27 parts of sorbitol, 18 parts of deionized water, 2.5 parts of sodium dodecyl sulfate, 1.1 parts of essence, 1 part of sodium monofluorophosphate, 0.9 part of sodium carboxymethylcellulose, 0.8 part of sodium silicate, 0.25 part of saccharin sodium, 0.25 part of trisodium phosphate, 0.15 part of monosodium phosphate and 0.03 part of paeoniflorin, wherein the paeoniflorin is extracted from paeony and has the purity of 95%.
Example 2
A toothpaste containing paeoniflorin comprises the following components in parts by weight: 48 parts of stone powder, 27 parts of sorbitol, 18 parts of deionized water, 2.5 parts of sodium dodecyl sulfate, 1.1 parts of essence, 1 part of sodium monofluorophosphate, 0.9 part of sodium carboxymethylcellulose, 0.8 part of sodium silicate, 0.25 part of saccharin sodium, 0.25 part of trisodium phosphate, 0.15 part of monosodium phosphate and 0.05 part of paeoniflorin, wherein the paeoniflorin is extracted from paeony and has the purity of 95%.
Example 3
A toothpaste containing paeoniflorin comprises the following components in parts by weight: 48 parts of stone powder, 27 parts of sorbitol, 18 parts of deionized water, 2.5 parts of sodium dodecyl sulfate, 1.1 parts of essence, 1 part of sodium monofluorophosphate, 0.9 part of sodium carboxymethylcellulose, 0.8 part of sodium silicate, 0.25 part of saccharin sodium, 0.25 part of trisodium phosphate, 0.15 part of monosodium phosphate and 0.1 part of paeoniflorin, wherein the paeoniflorin is extracted from paeoniflorin, and the purity of the paeoniflorin is 95%.
The toothpaste prepared by the above embodiments 1-3 has significant effects on bacteriostasis, inflammation diminishing, and gingival bleeding and gingival swelling prevention, the paeoniflorin is added into the functional components of the original toothpaste, and the toothpaste has the effects of bacteriostasis, inflammation diminishing, gingival swelling prevention and other gingival diseases, and the components cooperate with each other to have good effects on certain tooth and oral diseases.

Claims (4)

1. A toothpaste containing paeoniflorin is characterized in that: the paint comprises the following components in parts by weight: 35-50 parts of stone powder, 20-30 parts of sorbitol, 15-25 parts of deionized water, 1-3 parts of sodium dodecyl sulfate, 0.8-2 parts of essence, 0.5-2 parts of sodium monofluorophosphate, 0.3-1.5 parts of sodium carboxymethylcellulose, 0.3-1.5 parts of sodium silicate, 0.1-0.4 part of saccharin sodium, 0.1-0.4 part of trisodium phosphate, 0.1-0.3 part of monosodium phosphate and 0.03-0.1 part of paeoniflorin.
2. The toothpaste containing paeoniflorin of claim 1, wherein: the paint comprises the following components in parts by weight:
48 parts of stone powder, 27 parts of sorbitol, 18 parts of deionized water, 2.5 parts of sodium dodecyl sulfate, 1.1 parts of essence, 1 part of sodium monofluorophosphate, 0.9 part of sodium carboxymethylcellulose, 0.8 part of sodium silicate, 0.25 part of saccharin sodium, 0.25 part of trisodium phosphate, 0.15 part of monosodium phosphate and 0.05 part of paeoniflorin.
3. The toothpaste containing paeoniflorin of claim 1 or 2, wherein: the paeoniflorin is extracted from radix Paeoniae.
4. The toothpaste containing paeoniflorin of claim 1 or 2, wherein: the purity of the paeoniflorin is 95%.
CN201910882088.7A 2019-09-18 2019-09-18 Toothpaste containing paeoniflorin Pending CN110613626A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910882088.7A CN110613626A (en) 2019-09-18 2019-09-18 Toothpaste containing paeoniflorin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910882088.7A CN110613626A (en) 2019-09-18 2019-09-18 Toothpaste containing paeoniflorin

Publications (1)

Publication Number Publication Date
CN110613626A true CN110613626A (en) 2019-12-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910882088.7A Pending CN110613626A (en) 2019-09-18 2019-09-18 Toothpaste containing paeoniflorin

Country Status (1)

Country Link
CN (1) CN110613626A (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101085728A (en) * 2007-07-11 2007-12-12 浙江大学 Method for preparing paeonol and paeoniflorin from cortex moutan
CN102113971A (en) * 2010-12-17 2011-07-06 徐慧 Stomach invigorating toothpaste and preparation method thereof
CN103393549A (en) * 2013-08-01 2013-11-20 李海祥 Plant additive toothpaste and preparation method thereof
CN109172668A (en) * 2018-10-31 2019-01-11 何凤姣 A kind of drug and preparation method thereof for treating periodontitis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101085728A (en) * 2007-07-11 2007-12-12 浙江大学 Method for preparing paeonol and paeoniflorin from cortex moutan
CN102113971A (en) * 2010-12-17 2011-07-06 徐慧 Stomach invigorating toothpaste and preparation method thereof
CN103393549A (en) * 2013-08-01 2013-11-20 李海祥 Plant additive toothpaste and preparation method thereof
CN109172668A (en) * 2018-10-31 2019-01-11 何凤姣 A kind of drug and preparation method thereof for treating periodontitis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SUNSHINE 译: "J Periodontal Res:芍药苷可明显改善牙周炎症", 《HTTPS://WWW.MEDSCI.CN/ARTICLE/SHOW_ARTICLE.ASP?ID=85F7536E57F》 *

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Application publication date: 20191227

RJ01 Rejection of invention patent application after publication