CN110612127A - 预防口腔癌的方法 - Google Patents
预防口腔癌的方法 Download PDFInfo
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- CN110612127A CN110612127A CN201880031117.2A CN201880031117A CN110612127A CN 110612127 A CN110612127 A CN 110612127A CN 201880031117 A CN201880031117 A CN 201880031117A CN 110612127 A CN110612127 A CN 110612127A
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- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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- C12N2310/10—Type of nucleic acid
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Abstract
携带miR‑185的外泌体预防和治疗口腔癌的方法,以及包含经过改造的唾液外泌体的、用于预防和治疗口腔癌的药物组合物。
Description
PCT国内申请,说明书已公开。
Claims (27)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710330847 | 2017-05-11 | ||
CN201710330847X | 2017-05-11 | ||
PCT/CN2018/086347 WO2018205978A1 (zh) | 2017-05-11 | 2018-05-10 | 预防口腔癌的方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN110612127A true CN110612127A (zh) | 2019-12-24 |
CN110612127B CN110612127B (zh) | 2023-03-31 |
Family
ID=64104671
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201880031117.2A Active CN110612127B (zh) | 2017-05-11 | 2018-05-10 | 预防口腔癌的方法 |
CN201810444172.6A Pending CN108853131A (zh) | 2017-05-11 | 2018-05-10 | 携带miR-185的外泌体及其用途 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810444172.6A Pending CN108853131A (zh) | 2017-05-11 | 2018-05-10 | 携带miR-185的外泌体及其用途 |
Country Status (3)
Country | Link |
---|---|
US (2) | US20200268785A1 (zh) |
CN (2) | CN110612127B (zh) |
WO (1) | WO2018205978A1 (zh) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011029903A1 (en) * | 2009-09-10 | 2011-03-17 | Flemming Velin | Method for the preparation of micro-rna and its therapeutic application |
-
2018
- 2018-05-10 CN CN201880031117.2A patent/CN110612127B/zh active Active
- 2018-05-10 CN CN201810444172.6A patent/CN108853131A/zh active Pending
- 2018-05-10 WO PCT/CN2018/086347 patent/WO2018205978A1/zh unknown
-
2019
- 2019-11-11 US US16/680,374 patent/US20200268785A1/en not_active Abandoned
-
2021
- 2021-07-09 US US17/371,765 patent/US20220016157A1/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011029903A1 (en) * | 2009-09-10 | 2011-03-17 | Flemming Velin | Method for the preparation of micro-rna and its therapeutic application |
Non-Patent Citations (4)
Title |
---|
T SASAHIRA ET AL.: "Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer.", 《BR J CANCER.》 * |
TARA L JOHNSON ET AL.: "Inhibition of Cell Proliferation and MAP Kinase and Akt Pathways in Oral Squamous cell Carcinoma by Genistein and Biochanin A.", 《EVID BASED COMPLEMENT ALTERNAT MED.》 * |
XIN MA ET AL.: "MicroRNA-185 inhibits cell proliferation and induces cell apoptosis by targeting VEGFA directly in von Hippel-Lindau-inactivated clear cell renal cell carcinoma.", 《UROL ONCOL.》 * |
YUKARI TAKAHASHI ET AL.: "MiR-107 and MiR-185 can induce cell cycle arrest in human non small cell lung cancer cell lines.", 《PLOS ONE.》 * |
Also Published As
Publication number | Publication date |
---|---|
US20220016157A1 (en) | 2022-01-20 |
CN110612127B (zh) | 2023-03-31 |
CN108853131A (zh) | 2018-11-23 |
WO2018205978A1 (zh) | 2018-11-15 |
US20200268785A1 (en) | 2020-08-27 |
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