CN110575810B - Side-feeding reaction tube - Google Patents
Side-feeding reaction tube Download PDFInfo
- Publication number
- CN110575810B CN110575810B CN201910966846.3A CN201910966846A CN110575810B CN 110575810 B CN110575810 B CN 110575810B CN 201910966846 A CN201910966846 A CN 201910966846A CN 110575810 B CN110575810 B CN 110575810B
- Authority
- CN
- China
- Prior art keywords
- sealing
- upper cover
- pressing part
- annular
- cutting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000006243 chemical reaction Methods 0.000 title claims abstract description 21
- 238000007789 sealing Methods 0.000 claims abstract description 88
- 239000003814 drug Substances 0.000 claims abstract description 47
- 238000003825 pressing Methods 0.000 claims abstract description 47
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 32
- 230000000903 blocking effect Effects 0.000 claims description 5
- 239000007787 solid Substances 0.000 abstract description 13
- 239000007788 liquid Substances 0.000 abstract description 10
- 238000001514 detection method Methods 0.000 abstract description 8
- 238000000338 in vitro Methods 0.000 abstract description 4
- 238000004806 packaging method and process Methods 0.000 abstract description 2
- 238000009434 installation Methods 0.000 description 8
- 238000000034 method Methods 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 238000012864 cross contamination Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/24—Stationary reactors without moving elements inside
- B01J19/2415—Tubular reactors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J4/00—Feed or outlet devices; Feed or outlet control devices
- B01J4/001—Feed or outlet devices as such, e.g. feeding tubes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
Abstract
The invention discloses a side-entering reaction tube which comprises a tube body and an upper cover which are in sealing connection, wherein a medicine inlet window is formed in the upper cover, a sealing film is arranged at the medicine inlet window, a pressing part for packaging a reagent is arranged on the upper cover at the position corresponding to the sealing film, and the reagent in the pressing part naturally falls into the tube body after the sealing film is cut by the pressing part. The invention has the advantages that the structure is ingenious, a plurality of solid reagents can be packaged in the pressing part outside the tube body, when the liquid sample is used, the liquid sample is added into the tube body, and then the pressing part is pressed down, so that the solid reagents packaged in the pressing part enter the tube body in a non-axial mode, the mixing of the liquid sample and the reagents is realized, the repeated addition of the reaction reagents is not needed, the operation steps are simplified, the time and the labor are saved, the liquid sample can be matched with the existing in-vitro diagnostic equipment for use, and the detection efficiency is greatly improved.
Description
Technical Field
The invention relates to a reaction tube, in particular to a side-entering reaction tube for in-vitro diagnosis.
Background
The reaction tube is a medical consumable container most commonly used in the field of in-vitro detection and is used for mixing a sample and a reagent and carrying out subsequent reactions. The traditional reaction tube comprises a tube body and an upper cover, and when the reaction tube is used, samples and reagents in the reaction tube need to be sequentially mixed, and then subsequent reactions, detection, analysis and the like are carried out. When the traditional reaction tube is used, the cover opening and closing operation is needed once for each reagent addition, the requirements on the operation environment are high, the operation is complex, the time and the labor are wasted, and the working efficiency is low; the mixed reagent has long exposure time and is polluted; the whole operation process has the risk of mixed reagent being scattered on the operation table due to manual misoperation because of the large number of times of opening and closing the cover.
Disclosure of Invention
The invention aims to provide a side-entering reaction tube packaged with a reagent, which does not need to repeatedly open and close a cover to add the reagent, simplifies operation steps and improves working efficiency.
In order to achieve the above purpose, the invention adopts the following technical scheme:
the side-entering reaction tube comprises a tube body and an upper cover which are in sealing connection, wherein a medicine inlet window is formed in the upper cover, a sealing film is arranged at the medicine inlet window, a pressing part for packaging a reagent is arranged on the upper cover at the position corresponding to the sealing film, and the reagent in the pressing part naturally falls into the tube body after the sealing film is cut by the pressing part.
The top of the pressing part is connected with the upper cover into a whole through a connecting belt.
The pressing part comprises a pressing sheet, a sealing frame matched with the medicine inlet window is arranged on the inner side surface of the pressing sheet, a medicine storage box with a small upper part and a large lower part is arranged at the lower part of the sealing frame, an opening is arranged at the bottom of the medicine storage box, and an anti-drop part for blocking the opening at the bottom of the medicine storage box and preventing the medicine storage box from being opened is arranged at the lower part of the medicine inlet window; and a cutting part for cutting the sealing film is arranged on the side wall of the medicine storage box close to the sealing film.
The side wall of the medicine storage box, which is close to the sealing film, obliquely extends from the top to the upper cover to form a cutting inclined surface, and the cutting part comprises a lower cutting convex edge arranged on the cutting inclined surface and an upper cutting convex edge obliquely extending from the top of the lower cutting convex edge to the sealing frame.
And a sealing limit structure is arranged between the sealing frame and the medicine inlet window.
The sealing limit structure comprises an annular positioning groove arranged at the medicine inlet window and an annular sealing strip arranged at the edge of the sealing frame, an anti-falling hook used for blocking the annular sealing strip is arranged at the outer edge of the anti-falling part, and the annular sealing strip is sealed and blocked in the annular positioning groove after the pressing part is pressed in place.
The inner side surface of the upper cover is provided with a mounting groove matched with the upper part of the pipe body, and a sealing structure is arranged between the pipe body and the mounting groove.
The sealing structure comprises an annular groove formed in the side wall of the mounting groove and an annular convex strip arranged on the outer side face of the pipe body, and the convex strip is sealed and clamped in the annular groove.
The upper cover and the pressing part are of an integrated structure.
The invention has ingenious structure, various solid reagents can be packaged in the pressing part outside the tube body, when in use, the liquid sample is added into the tube body, and then the pressing part is pressed down, so that the solid reagents packaged in the pressing part enter the tube body in a non-axial mode, the mixing of the liquid sample and the reagents is realized, the repeated addition of the reaction reagents is not needed, the operation steps are simplified, the time and the labor are saved, the liquid sample can be matched with the existing in-vitro diagnostic equipment for use, and the detection efficiency is greatly improved.
The top of the cutting part and the top of the sealing frame are spaced, so that the upper part of the sealing film is connected with the upper cover after the pressing part is in place, and the sealing film is prevented from falling into the pipe body to influence detection. The bottom of the annular sealing strip is positioned at the unhooking prevention position in the non-use state, so that the pressing part is prevented from opening, and the solid reagent packaged in the medicine storage box is prevented from falling off; after being pressed in place, the annular sealing strip is sealed and clamped in the annular positioning groove, so that the sealing performance of the pipe body is ensured, the pipe body can be used for reaction, detection and analysis, the whole detection process is carried out in the sealing cavity, and cross contamination is avoided.
Drawings
Fig. 1 is a schematic structural view of the present invention.
Fig. 2 is an enlarged schematic view of the portion a in fig. 1.
Fig. 3 is an enlarged schematic view of the portion B in fig. 1.
Fig. 4 is a state of use diagram of the present invention.
Fig. 5 is an open state of the pressing portion according to the present invention.
Detailed Description
As shown in fig. 1, the side-entering reaction tube comprises a tube body 1 and an upper cover 2 which are connected in a sealing way, wherein a medicine inlet window is formed in the side wall of the upper cover 2, a sealing film 3 is arranged at the medicine inlet window, and the sealing film 3 and the upper cover are integrally formed, so that the cost is reduced; the pressing part which is encapsulated with solid reagent (of course, the solid reagent can also be liquid reagent encapsulated in the sealing bag) is arranged on the outer side of the upper cover 2 at the position corresponding to the sealing film 3, and the solid reagent can be one, two, three or more according to detection items; the top of the pressing part is connected with the upper cover 2 into a whole through the connecting belt 4, and when in use, the pressing part is pressed to cut the sealing film 3, and then the solid reagent packaged in the pressing part naturally falls into the pipe body 1.
As shown in fig. 1-5, the pressing part is of an integrated structure, the pressing part comprises a pressing sheet 5.1, the inner side surface of the pressing sheet 5.1 is provided with a sealing frame 5.2 matched with a medicine inlet window, the lower part of the sealing frame 5.2 is provided with a medicine storage box 5.3 with a small upper part and a big lower part and an opening at the bottom, and the lower part of the medicine inlet window is correspondingly provided with an anti-drop part 5.4 for blocking the medicine storage box and preventing the medicine storage box from opening; a sealing limit structure is arranged between the sealing frame 5.2 and the medicine inlet window, the sealing limit structure comprises an annular positioning groove 5.5 arranged at the medicine inlet window and an annular sealing strip 5.6 arranged at the edge of the sealing frame 5.2, an anti-falling hook 5.7 is arranged at the outer edge of the anti-falling part 5.4, the annular sealing strip 5.6 is positioned at the inner side of the anti-falling hook 5.7 when the medicine storage box is not used (i.e. in a delivery state), the anti-falling hook 5.7 is used for clamping the annular sealing strip 5.6, the pressing part is prevented from being opened, and solid reagents sealed in the medicine storage box 5.3 are prevented from falling out;
the side wall of the medicine storage box 5.3 close to the sealing film 3 obliquely extends from the top to the upper cover to form a cutting inclined plane, a cutting part for cutting the sealing film 3 is arranged on the cutting inclined plane, the cutting part comprises a lower cutting convex edge 6.1 arranged on the cutting inclined plane and an upper cutting convex edge 6.2 obliquely extending from the top of the lower cutting convex edge 6.1 to the sealing frame 5.2 (of course, in actual processing, the cutting part can also be a saw-tooth-shaped slice extending along the oblique direction of the cutting inclined plane, or a transverse cutting piece vertically arranged at the bottom of the cutting inclined plane, or other cutting structures capable of cutting the sealing film), the pressing part is pressed to rotate in the upward cover direction, the bottom of the lower cutting convex edge 6.1 firstly contacts the sealing film 3 and punctures the sealing film 3, the annular sealing strip 5.6 on the sealing frame 5.2 is sealed and clamped in the annular positioning groove 5.5 after the pressing part is in place, the bottom opening of the medicine storage box 5.3 is positioned in the inner cavity of the upper cover 2, and solid reagent packaged in the medicine storage box 5.3 naturally falls into the tube body 1.
In actual processing, as shown in fig. 1, an installation groove 7 matched with the upper part of the pipe body 1 is formed on the inner side surface of the upper cover 2, the annular top wall of the installation groove 7 forms a sealing table surface, the upper part of the pipe body 1 is inserted in the installation groove 7 in a sealing way (of course, in actual processing, the installation groove 7 can be formed on the inner side surface of the pipe body 1, the upper cover 2 is inserted in the installation groove 7 in a sealing way, the pipe body 1 and the upper cover 2 can be connected into a whole in a threaded way, and can be connected into a whole in other connecting ways); a sealing structure is arranged between the pipe body 1 and the installation groove 7, the sealing structure comprises an annular groove formed in the side wall of the installation groove 7 and an annular raised line 8 formed in the outer side surface of the pipe body 1, and the annular raised line 8 is clamped in the annular groove in a sealing manner (of course, according to practical conditions, the annular raised line 8 can be formed in the side wall of the installation groove 7, and the annular groove is correspondingly formed in the outer side wall of the pipe body 1).
In the factory state of the reaction tube, the bottom of the pressing part is clamped at the inner side of the anti-unhooking hook 5.7, so that the reagent is prevented from falling out due to the opening of the pressing part, and the reaction tube is particularly shown in figure 1; in the use state, the sealing frame of the pressing part is sealed and clamped at the medicine inlet window, and the medicine storage box is positioned in the inner cavity of the upper cover, as shown in fig. 4.
When the device is used, the pipe body 1 is opened by manual operation or external power, a liquid sample to be detected is added into the pipe body 1, and then the pipe body 1 and the upper cover 2 are sealed and inserted into a whole; the pressing part is manually pressed or by using external power to move towards the upper cover, the bottom of the cutting part is firstly contacted with the sealing film 3 and is pierced, the pressing part is continuously pressed inwards, the sealing film 3 is cut off in the inward movement process of the lower cutting convex ridge 6.1 and the upper cutting convex ridge 6.2, and the upper part of the sealing film 3 is still connected with the part where the medicine inlet window exists after the pressing part is in place because the space exists between the top of the upper cutting convex ridge 6.2 and the top of the sealing frame 5.2; the annular sealing strip 5.6 on the sealing frame 5.2 is clamped in the annular positioning groove 5.5 in a sealing way after the pressing part is in place, the bottom opening of the medicine storage box 5.3 is positioned in the inner cavity of the upper cover 2, and the solid reagent packaged in the medicine storage box 5.3 naturally falls into the tube body 1, so that the liquid sample to be detected and the solid reagent are completely mixed.
Claims (4)
1. The utility model provides a side-entering reaction tube, includes sealing connection's body and upper cover, its characterized in that: a medicine inlet window is formed in the side wall of the upper cover, a sealing film is arranged at the medicine inlet window, and the sealing film and the upper cover are integrally formed; a pressing part which is encapsulated with a reagent is arranged on the upper cover at the position corresponding to the sealing film, and after the sealing film is cut by the pressing part, the reagent encapsulated in the pressing part naturally falls into the tube body in a non-axial mode;
the pressing part comprises a pressing sheet, a sealing frame matched with the medicine inlet window is arranged on the inner side surface of the pressing sheet, a medicine storage box with a small upper part and a large lower part is arranged at the lower part of the sealing frame, an opening is arranged at the bottom of the medicine storage box, and an anti-drop part for blocking the opening at the bottom of the medicine storage box and preventing the medicine storage box from being opened is arranged at the lower part of the medicine inlet window; a cutting part for cutting the sealing film is arranged on the side wall of the medicine storage box close to the sealing film; the side wall of the medicine storage box, which is close to the sealing film, obliquely extends from the top to the upper cover to form a cutting inclined surface, and the cutting part comprises a lower cutting convex edge arranged on the cutting inclined surface and an upper cutting convex edge obliquely extending from the top of the lower cutting convex edge to the sealing frame;
a sealing limit structure is arranged between the sealing frame and the medicine inlet window and comprises an annular positioning groove arranged at the medicine inlet window and an annular sealing strip arranged at the edge of the sealing frame, and an anti-falling hook for blocking the annular sealing strip is arranged at the outer edge of the anti-falling part; the medicine inlet window is also provided with an annular positioning groove, and the annular sealing strip is clamped in the annular positioning groove in a sealing way after the pressing part is pressed in place.
2. The side entry reactor tube of claim 1, wherein: the inner side surface of the upper cover is provided with a mounting groove matched with the upper part of the pipe body, and a sealing structure is arranged between the pipe body and the mounting groove.
3. The side entry reactor tube of claim 2, wherein: the sealing structure comprises an annular groove formed in the side wall of the mounting groove and an annular raised line arranged on the outer side face of the pipe body, and the annular raised line is clamped in the annular groove in a sealing manner.
4. The side entry reactor tube of claim 1, wherein: the upper cover and the pressing part are of an integrated structure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910966846.3A CN110575810B (en) | 2019-10-12 | 2019-10-12 | Side-feeding reaction tube |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910966846.3A CN110575810B (en) | 2019-10-12 | 2019-10-12 | Side-feeding reaction tube |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110575810A CN110575810A (en) | 2019-12-17 |
| CN110575810B true CN110575810B (en) | 2024-02-23 |
Family
ID=68814501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910966846.3A Active CN110575810B (en) | 2019-10-12 | 2019-10-12 | Side-feeding reaction tube |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110575810B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111272744B (en) * | 2020-01-21 | 2022-03-11 | 北京理工大学珠海学院 | Detection apparatus for antibiotic in detection cow's milk |
| CN113150965B (en) * | 2021-04-21 | 2023-07-25 | 西安交通大学 | Anti-pollution detection tube and CRISPR molecular diagnosis detection method based on same |
| CN117427371B (en) * | 2023-12-21 | 2024-03-15 | 山西其右建材科技有限公司 | Extraction equipment for preparing 3-mercaptopropionic acid co-production ammonia water |
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|---|---|---|---|---|
| DE2518428A1 (en) * | 1975-04-25 | 1976-11-04 | Cellpack Ag | Container for storing and mixing at least two reactants - latter located inside compartments sepd. by destructable partition |
| DE29724473U1 (en) * | 1997-09-11 | 2001-08-30 | Biopsytec Gmbh | Sample capsule for taking biological samples |
| TWM246309U (en) * | 2003-07-17 | 2004-10-11 | Li-Li Shiu | Container device with separating storage structure |
| CN1703354A (en) * | 2002-10-10 | 2005-11-30 | 利奥工程有限公司 | Improvements to two-part vessels |
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| KR101444020B1 (en) * | 2013-04-23 | 2014-09-23 | 성구환 | Container spigot for button system |
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| CN206125812U (en) * | 2016-11-01 | 2017-04-26 | 四川大学 | Anti -fake storage bottle lid |
| CN207042508U (en) * | 2017-08-01 | 2018-02-27 | 侯嘉凝 | A kind of chemistry dropper |
| EP3520896A1 (en) * | 2018-02-02 | 2019-08-07 | Dispendix GmbH | Automated volumetric device |
| CN110229745A (en) * | 2019-07-22 | 2019-09-13 | 安图实验仪器(郑州)有限公司 | Push type reaction tube |
| CN210934979U (en) * | 2019-10-12 | 2020-07-07 | 安图实验仪器(郑州)有限公司 | Side-feeding reaction tube |
-
2019
- 2019-10-12 CN CN201910966846.3A patent/CN110575810B/en active Active
Patent Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2518428A1 (en) * | 1975-04-25 | 1976-11-04 | Cellpack Ag | Container for storing and mixing at least two reactants - latter located inside compartments sepd. by destructable partition |
| DE29724473U1 (en) * | 1997-09-11 | 2001-08-30 | Biopsytec Gmbh | Sample capsule for taking biological samples |
| CN1703354A (en) * | 2002-10-10 | 2005-11-30 | 利奥工程有限公司 | Improvements to two-part vessels |
| TWM246309U (en) * | 2003-07-17 | 2004-10-11 | Li-Li Shiu | Container device with separating storage structure |
| CN2920237Y (en) * | 2006-02-27 | 2007-07-11 | 长沙楚天科技有限公司 | Pressing internal through baffle device |
| CN201208560Y (en) * | 2008-06-03 | 2009-03-18 | 四川省迈克科技有限责任公司 | Puncturing diagnostic reagent packing bottle with expansion film |
| KR101444020B1 (en) * | 2013-04-23 | 2014-09-23 | 성구환 | Container spigot for button system |
| EP2905079A1 (en) * | 2014-02-10 | 2015-08-12 | Robert Bosch Gmbh | Device for storing a fluid in a microfluidic system, method for operating and method for producing such a device |
| CN206125812U (en) * | 2016-11-01 | 2017-04-26 | 四川大学 | Anti -fake storage bottle lid |
| CN207042508U (en) * | 2017-08-01 | 2018-02-27 | 侯嘉凝 | A kind of chemistry dropper |
| EP3520896A1 (en) * | 2018-02-02 | 2019-08-07 | Dispendix GmbH | Automated volumetric device |
| CN110229745A (en) * | 2019-07-22 | 2019-09-13 | 安图实验仪器(郑州)有限公司 | Push type reaction tube |
| CN210934979U (en) * | 2019-10-12 | 2020-07-07 | 安图实验仪器(郑州)有限公司 | Side-feeding reaction tube |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110575810A (en) | 2019-12-17 |
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| CP03 | Change of name, title or address |
Address after: 450016 No.199, Jingkai 15th Street, Zhengzhou Economic and Technological Development Zone, Henan Province Patentee after: AUTOBIO LABTEC INSTRUMENTS Co.,Ltd. Country or region after: China Address before: No. 199, 15th Street, economic and Technological Development Zone, Zhengzhou City, Henan Province Patentee before: AUTOBIO LABTEC INSTRUMENTS Co.,Ltd. Country or region before: China |
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