CN110575625A - method for manufacturing tissue equivalent compensator for radiotherapy - Google Patents
method for manufacturing tissue equivalent compensator for radiotherapy Download PDFInfo
- Publication number
- CN110575625A CN110575625A CN201910879448.8A CN201910879448A CN110575625A CN 110575625 A CN110575625 A CN 110575625A CN 201910879448 A CN201910879448 A CN 201910879448A CN 110575625 A CN110575625 A CN 110575625A
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- China
- Prior art keywords
- data model
- tissue equivalent
- dimensional data
- patient
- radiotherapy
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
- B29C64/30—Auxiliary operations or equipment
- B29C64/386—Data acquisition or data processing for additive manufacturing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y50/00—Data acquisition or data processing for additive manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
- A61N2005/1096—Elements inserted into the radiation path placed on the patient, e.g. bags, bolus, compensators
Abstract
the invention relates to a method for manufacturing a medical model, in particular to a method for manufacturing a radiation therapy tissue equivalent compensator, which comprises the following steps: s1, acquiring a three-dimensional data model of the part of the patient needing radiotherapy; s2, reversely calculating a three-dimensional data model of a tissue equivalent compensator complementary with the part needing radiation therapy according to the three-dimensional data model of the part needing radiation therapy of the patient; and S3, inputting the three-dimensional data model of the tissue equivalent compensator into a 3D printer, and printing the tissue equivalent compensator. The tissue equivalent compensator manufactured by the manufacturing method has high precision and good conformability, does not need to manufacture a three-dimensional model of a part to be treated, directly prints out the tissue equivalent compensator, and reduces unnecessary operation links.
Description
Technical Field
The invention relates to a method for manufacturing a medical model, in particular to a method for manufacturing a radiation therapy tissue equivalent compensator.
background
Radiation therapy is one of the main therapeutic approaches for tumor therapy. The world health organization counts that about seventy percent of tumor patients require radiation therapy throughout the treatment. Radiotherapy is the treatment of tumors by killing cancer cells with high energy particles or radiation.
in the process of tumor radiotherapy, in order to ensure the accuracy and uniformity of radiation dose, the dose compensation is carried out on patients with tissue loss or special parts of the body surface by tissue equivalent fillers, so that the dose distribution of a radiation target area is accurate and uniform. Clinically common tissue equivalent fillers do not contact the radiotherapy site tightly and have poor conformity, thus affecting the accuracy and uniformity of the radiation dose. Therefore, the inventor invents a tissue equivalent compensator manufacturing method which has high scanning precision and good conformality of the manufactured tissue equivalent compensator through years of radiotherapy experience.
Disclosure of Invention
In order to solve the technical problems mentioned in the background technology, the invention provides a method for manufacturing a tissue equivalent compensator for radiotherapy, the tissue equivalent compensator manufactured by the method has high precision and good conformability, and the defects of loose contact and gap existing between the tissue equivalent compensator and a radiotherapy part in clinic can be avoided.
The technical scheme adopted by the invention is as follows:
a method for manufacturing a radiation therapy tissue equivalent compensator comprises the following steps:
s1, acquiring a three-dimensional data model of the part of the patient needing radiotherapy;
s2, reversely calculating a three-dimensional data model of a tissue equivalent compensator complementary with the part needing radiation therapy according to the three-dimensional data model of the part needing radiation therapy of the patient;
And S3, inputting the three-dimensional data model of the tissue equivalent compensator into a 3D printer, and printing the tissue equivalent compensator.
In the above method for manufacturing the equivalent compensator for tissue radiotherapy, in S1, the method for obtaining the three-dimensional data model of the part of the patient requiring radiation therapy includes performing three-dimensional scanning on the part of the patient requiring radiation therapy by using a three-dimensional scanner, and performing data processing to obtain the three-dimensional data model of the part of the patient requiring radiation therapy.
The method for manufacturing the radiotherapy tissue equivalent compensator comprises the following steps of:
s101, placing a patient on a glass plate, wherein a guide rail is arranged above the glass plate, and a CCD industrial camera and a laser are arranged on the guide rail;
S102, driving a CCD industrial camera and a laser to synchronously move on a guide rail above a patient, and performing three-dimensional scanning on the part of the patient needing radiotherapy;
S103, after the scanning is finished, the CCD industrial camera transmits the image to an external computer, the external computer processes the image, the pixel where the laser stripe is located is identified after the image processing, and the coordinates of the three-dimensional space points corresponding to the pixel points in a static world coordinate system are reversely calculated through a light plane equation calibrated in advance and the CCD industrial camera;
and S104, splicing the three-dimensional space points by an external computer through a pre-calibrated spatial relationship to obtain a three-dimensional data model of the part of the patient needing radiotherapy.
The method for manufacturing the tissue equivalent compensator for radiotherapy is characterized in that the swept plane of the CCD industrial camera and the laser moving on the guide rail is parallel to the upper plane of the glass plate.
in the above method for manufacturing a tissue equivalent compensator for radiotherapy, the method for calculating a three-dimensional data model of a tissue equivalent compensator complementary to the site requiring radiotherapy in reverse direction in S2 includes the following steps:
S201, establishing two parallel coordinate planes, wherein the part needing radiotherapy is positioned between the two coordinate planes;
S202, calculating the distance between the two coordinate planes in the S201, and defining one coordinate plane as a reference plane;
s203, calculating the distance to a reference plane according to the three-dimensional data model of the part of the patient needing radiotherapy;
and S204, subtracting the distance between the three-dimensional data model in the S203 and the reference plane by using the distance between the two coordinate planes calculated in the S202 to obtain the three-dimensional data model of the tissue equivalent compensator.
the invention has the following technical effects:
The radiotherapy tissue equivalent compensator manufactured by the manufacturing method of the invention adopts the three-dimensional scanner to carry out three-dimensional scanning, has high scanning precision, obtains a three-dimensional data model of a part of a patient which is closer to reality and needs radiotherapy, directly and reversely calculates to obtain the three-dimensional data model of the tissue equivalent compensator according to the three-dimensional data model, inputs the three-dimensional data model of the tissue equivalent compensator into the 3D printer to directly print to obtain a required model, and the calculation processes can be realized by programming, thereby reducing the operation steps, needing no model pouring process and simplifying the operation.
Detailed Description
The invention provides a method for manufacturing a tissue equivalent compensator for radiotherapy, which comprises the following steps:
Firstly, acquiring a three-dimensional data model of a part of a patient needing radiotherapy; the method for acquiring the three-dimensional data model of the part of the patient needing radiotherapy comprises the steps of performing three-dimensional scanning on the part of the patient needing radiotherapy by using a three-dimensional scanner, and processing data to obtain the three-dimensional data model of the part of the patient needing radiotherapy; the three-dimensional scanning process of the three-dimensional scanner comprises the following steps of firstly placing a patient on a glass plate, arranging a guide rail above the glass plate, and arranging a CCD industrial camera and a laser on the guide rail; further, the CCD industrial camera and the laser are driven to synchronously move on a guide rail above the patient, and the part of the patient needing radiotherapy is scanned in three dimensions; after scanning is finished, the CCD industrial camera transmits an image to an external computer, the external computer processes the image, pixels where the laser stripes are located are identified after the image processing, and coordinates of three-dimensional space points corresponding to the pixels in a static world coordinate system are calculated back through a light plane equation calibrated in advance and the CCD industrial camera; and the external computer splices the three-dimensional space points through a pre-calibrated spatial relationship to obtain a three-dimensional data model of the part of the patient needing radiotherapy.
then, according to the three-dimensional data model of the part of the patient needing radiation treatment, reversely calculating the three-dimensional data model of the tissue equivalent compensator which is complementary with the part needing radiation treatment; specifically, the following steps are adopted:
Establishing two parallel coordinate planes, wherein the part needing radiation treatment is positioned between the two coordinate planes; calculating the distance between two coordinate planes, and defining one coordinate plane as a reference plane; calculating the distance to a reference plane according to the three-dimensional data model of the part of the patient needing radiation treatment; and subtracting the distance between the three-dimensional data model of the part needing to be treated and the reference plane by using the calculated distance between the two coordinate planes to obtain the three-dimensional data model of the tissue equivalent compensator.
it should be noted that the reference plane is preferably a plane parallel to the glass plate, or a plane tangential to the highest point of the curved contour of the part of the patient to be treated is selected.
And finally, inputting the three-dimensional data model of the tissue equivalent compensator into a 3D printer, and printing the tissue equivalent compensator to obtain the tissue equivalent compensator. Wherein the material that 3D printer printed selects polylactic acid for use.
the rapidly manufactured individual tissue equivalent filler can be closely contacted with the body of a patient, the distribution of the radiation dose is uniform, and meanwhile, the polylactic acid of the tissue equivalent filler has a good equivalent physical special effect, so that the accuracy and the uniformity of the radiation dose are improved.
the above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and the present invention shall be covered thereby.
Claims (5)
1. a method for manufacturing a tissue equivalent compensator for radiotherapy; the method is characterized by comprising the following steps:
s1, acquiring a three-dimensional data model of the part of the patient needing radiotherapy;
s2, reversely calculating a three-dimensional data model of a tissue equivalent compensator complementary with the part needing radiation therapy according to the three-dimensional data model of the part needing radiation therapy of the patient;
And S3, inputting the three-dimensional data model of the tissue equivalent compensator into a 3D printer, and printing the tissue equivalent compensator.
2. the method for preparing a tissue equivalent compensator according to claim 1, wherein the step of obtaining the three-dimensional data model of the part of the patient requiring radiation therapy in S1 is to perform three-dimensional scanning on the part of the patient requiring radiation therapy by using a three-dimensional scanner, and obtain the three-dimensional data model of the part of the patient requiring radiation therapy after data processing.
3. The method for preparing tissue equivalent compensator according to claim 1, wherein the method for calculating the three-dimensional data model of tissue equivalent compensator complementary to the desired radiation treatment site in S2 comprises the following steps:
s201, establishing two parallel coordinate planes, wherein the part needing radiotherapy is positioned between the two coordinate planes;
S202, calculating the distance between the two coordinate planes in the S201, and defining one coordinate plane as a reference plane;
S203, calculating the distance to a reference plane according to the three-dimensional data model of the part of the patient needing radiotherapy;
and S204, subtracting the distance between the three-dimensional data model in the S203 and the reference plane by using the distance between the two coordinate planes calculated in the S202 to obtain the three-dimensional data model of the tissue equivalent compensator.
4. The method for producing a tissue equivalent compensator according to claim 2, wherein the step of three-dimensionally scanning the part of the patient requiring radiotherapy by the three-dimensional scanner comprises:
S101, placing a patient on a glass plate, wherein a guide rail is arranged above the glass plate, and a CCD industrial camera and a laser are arranged on the guide rail;
S102, driving a CCD industrial camera and a laser to synchronously move on a guide rail above a patient, and performing three-dimensional scanning on the part of the patient needing radiotherapy;
s103, after the scanning is finished, the CCD industrial camera transmits the image to an external computer, the external computer processes the image, the pixel where the laser stripe is located is identified after the image processing, and the coordinates of the three-dimensional space points corresponding to the pixel points in a static world coordinate system are reversely calculated through a light plane equation calibrated in advance and the CCD industrial camera;
And S104, splicing the three-dimensional space points by an external computer through a pre-calibrated spatial relationship to obtain a three-dimensional data model of the part of the patient needing radiotherapy.
5. the method of claim 4, wherein the swept plane of the CCD industrial camera and laser moving on the guide rail is parallel to the upper plane of the glass plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201910879448.8A CN110575625A (en) | 2019-09-18 | 2019-09-18 | method for manufacturing tissue equivalent compensator for radiotherapy |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910879448.8A CN110575625A (en) | 2019-09-18 | 2019-09-18 | method for manufacturing tissue equivalent compensator for radiotherapy |
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| CN110575625A true CN110575625A (en) | 2019-12-17 |
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| CN201910879448.8A Pending CN110575625A (en) | 2019-09-18 | 2019-09-18 | method for manufacturing tissue equivalent compensator for radiotherapy |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116092632A (en) * | 2023-03-15 | 2023-05-09 | 南京谷睿生物科技有限公司 | Nuclear medicine imaging data analysis method for radiopharmaceutical evaluation |
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| CN104971438A (en) * | 2015-07-24 | 2015-10-14 | 上海交通大学医学院附属第九人民医院 | Tissue equivalent compensator manufacturing method and tissue equivalent compensator |
| WO2016099142A1 (en) * | 2014-12-16 | 2016-06-23 | 사회복지법인 삼성생명공익재단 | Method for manufacturing radiation intensity modulating body and device for manufacturing same |
| CN106039598A (en) * | 2016-06-30 | 2016-10-26 | 北京启麟科技有限公司 | Tissue equivalent replenisher for radiotherapy and preparation method thereof |
| CN107261339A (en) * | 2017-06-09 | 2017-10-20 | 北京全域医疗技术有限公司 | The generation method and device of breast localization film |
| CN108888875A (en) * | 2018-06-28 | 2018-11-27 | 广州医科大学附属肿瘤医院 | A kind of body irradiation tissue compensation device and preparation method thereof |
| CN110975169A (en) * | 2019-09-17 | 2020-04-10 | 北京大学第三医院 | Method for manufacturing tissue equivalent compensator for radiotherapy |
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2019
- 2019-09-18 CN CN201910879448.8A patent/CN110575625A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2016099142A1 (en) * | 2014-12-16 | 2016-06-23 | 사회복지법인 삼성생명공익재단 | Method for manufacturing radiation intensity modulating body and device for manufacturing same |
| CN104881864A (en) * | 2015-04-14 | 2015-09-02 | 精迪测量技术（上海）有限公司 | Human body head three dimensional scanner and three-dimensional modeling method |
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| CN106039598A (en) * | 2016-06-30 | 2016-10-26 | 北京启麟科技有限公司 | Tissue equivalent replenisher for radiotherapy and preparation method thereof |
| CN107261339A (en) * | 2017-06-09 | 2017-10-20 | 北京全域医疗技术有限公司 | The generation method and device of breast localization film |
| CN108888875A (en) * | 2018-06-28 | 2018-11-27 | 广州医科大学附属肿瘤医院 | A kind of body irradiation tissue compensation device and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN116092632A (en) * | 2023-03-15 | 2023-05-09 | 南京谷睿生物科技有限公司 | Nuclear medicine imaging data analysis method for radiopharmaceutical evaluation |
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Application publication date: 20191217 |