CN110554185A - Feeding device of full-automatic lateral chromatography detection system - Google Patents
Feeding device of full-automatic lateral chromatography detection system Download PDFInfo
- Publication number
- CN110554185A CN110554185A CN201810557852.9A CN201810557852A CN110554185A CN 110554185 A CN110554185 A CN 110554185A CN 201810557852 A CN201810557852 A CN 201810557852A CN 110554185 A CN110554185 A CN 110554185A
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- China
- Prior art keywords
- detection
- feeding
- feeding device
- mortise
- lateral chromatography
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- Pending
Links
- 238000001514 detection method Methods 0.000 title claims abstract description 146
- 238000004587 chromatography analysis Methods 0.000 title claims abstract description 26
- 239000000463 material Substances 0.000 claims abstract description 9
- 238000007599 discharging Methods 0.000 claims description 4
- 238000003556 assay Methods 0.000 claims 3
- 230000036039 immunity Effects 0.000 abstract 1
- 230000007306 turnover Effects 0.000 abstract 1
- 230000000452 restraining effect Effects 0.000 description 10
- 230000005540 biological transmission Effects 0.000 description 6
- 230000000712 assembly Effects 0.000 description 5
- 238000000429 assembly Methods 0.000 description 5
- 238000006073 displacement reaction Methods 0.000 description 4
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
Abstract
The invention belongs to the field of immune lateral chromatography detection, and particularly relates to a feeding device of a full-automatic lateral chromatography detection system and a detection card thereof. Including a horizontal feedstock channel and detection channel mouth, the vertical feeder hopper that sets up on detection channel, the feeder hopper below is provided with the discharge gate that pushes away the material mouth and towards detection channel mouth that supplies the feed arm business turn over, arranges a plurality of immunity side direction chromatography detection cards in the feeder hopper. One side or both sides of feed channel are provided with the inclined plane that makes things convenient for immune lateral chromatography to detect the card and enter into the detection channel mouth, and the detection channel mouth is provided with the limiting plate of upwards sloping, and the inclined plane is provided with the restraint limit to detection channel mouth direction, and restraint limit, limiting plate, feed channel form a spacing cavity jointly. The detection card arranged in the feed hopper is used for full-automatic lateral chromatography detection.
Description
Technical Field
The invention belongs to the field of immune lateral chromatography detection, and particularly relates to a feeding device of a full-automatic lateral chromatography detection system and a detection card thereof.
background
At present, the full-automatic lateral chromatography detection system is mainly used for detecting and analyzing various proteins, antigens and the like in body fluids such as human serum, plasma, whole blood, urine and the like, and is the mainstream of in-vitro diagnosis at present. With the development of the medical industry, full automation is a necessary trend of in vitro diagnosis, and a full-automatic system can reduce manual errors and improve detection speed.
In the existing market, some full-automatic detection systems generally convey the detection cards one by one to corresponding card-clamping molds in the detection process, and then sample adding, incubation and detection are carried out in the molds, so that the system has high process requirements and high production cost. The invention CN104345157B discloses a reagent card box, which can realize automatic and orderly output of reagent cards, and has the advantages of high production cost due to the fact that different reagent cards need to be opened separately. Utility model CN206208908U discloses a detect card fixing device and detector thereof, this fixing device need use special mold opening tool to the detection card quantity that once only can hold is limited.
Disclosure of Invention
In order to solve the above problems, the present invention provides a feeding device of a full-automatic lateral chromatography detection system and a detection card thereof, wherein the feeding device is a part of the full-automatic lateral chromatography detection system, and the feeding device feeds the detection card for detection into a sample adding test area of the system during detection. The feeding device comprises a transverse feeding channel and a detection channel opening, wherein a feeding hopper is vertically arranged on the detection channel, a material pushing opening for feeding and discharging a feeding arm and a material discharging opening facing the detection channel opening are formed below the feeding hopper, a plurality of immune lateral chromatography detection cards are arranged in the feeding hopper, each detection card comprises a sample adding area, a detection area and at least one connection area, each connection area is provided with at least one tenon structure and at least one mortise structure, the sample adding areas and the detection areas are arranged on a first plane of the detection cards, and the tenon structures and the mortise structures are respectively positioned on two sides of the first plane. The two sides of the feed hopper of the feeding device form clamping surfaces with positions corresponding to the tenon structure and the mortise structure.
And one side or two sides of the feeding channel are provided with inclined planes which are convenient for the immune lateral chromatography detection card to enter the detection channel opening.
And the detection channel port is provided with a limiting plate which is inclined upwards.
The inclined plane of the feeding channel is provided with a restraining edge towards the direction of the opening of the detection channel, and the restraining edge, the limiting plate and the feeding channel form a limiting cavity together.
Any two parallel planes of the feed hopper can be opened outwards along the horizontal direction and can also be clamped inwards along the horizontal direction.
The tenon structure and the mortise structure are arranged on the other two sides of the first plane.
The plurality of detection cards are connected into a mortise and tenon structure through the mortise and tenon structure.
The tenon structure and the mortise structure of joining region, the tenon structure protrusion detects the card side, the mortise structure is sunken to detect the card side.
the tenon structure and the mortise structure are the same in shape structure, and are symmetrical relative to the detection area and the sample adding area.
The sections of the tenon structure and the mortise structure are rectangular or polygonal; the width of the tenon structure and the mortise structure is equal to or less than that of the side face.
The feeding device is simple in structure, different detection cards do not need to be specially opened, and the number of the detection cards which can be accommodated at one time can be controlled as required. The design of the partial detection card mortise and tenon structure in the full-automatic lateral chromatography detection system is combined with the feeding device, so that the arrangement of a detection card fixing device is omitted, and the cost is effectively reduced.
Drawings
FIG. 1: a feeding device (500-feeding device, 501-feeding hopper, 503-pushing port, 504-feeding arm, 505-inclined plane, 506-restraining edge, 507-detecting channel port, 509-feeding channel, 510-limiting plate);
FIG. 2: a feeding device (508-discharge port);
FIG. 3: the detection card 1 (200-detection card, 201-detection zone, 202-sample addition zone, 203-tenon structure, 204-mortise structure, 205-right side surface of detection card, 206-left side surface of detection card, 208-coincidence line of upper shell and bottom plate) used in the design;
FIG. 4: the feeding device in use (500-feeding device, 501-feeding hopper, 502-detection card, 503-pushing port, 504-feeding arm, 505-inclined plane, 506-restraining edge, 507-detection channel port, 510-limiting plate).
FIG. 5: the detection card 2 used in the design (400-detection card, 401-detection zone, 402-sample addition zone, 403-tenon structure, 404-mortise structure, 405-tenon structure, 406-mortise structure, 407-detection card right side, 408-detection card left side, 409-detection card upper side, 410-detection card bottom plate, 412-coincidence line of upper shell and bottom plate);
FIG. 6: detecting a card combination 1 (207-mortise and tenon structure);
FIG. 7: a detection card combination 2 (411-mortise and tenon structure);
Detailed Description
To facilitate an understanding of the invention, the invention is described more fully below with reference to the accompanying drawings. The present invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein.
Example 1
as shown in fig. 3, the detection card of the present invention includes a detection card 200, a detection area 201, a sample addition area 202, a tenon structure 203, a mortise structure 204, a detection card right side 205, a detection card left side 206, and a line 208 formed by overlapping the upper shell and the bottom plate. As shown in fig. 1 and fig. 2, the feeding device is a perspective view, and the feeding device includes a feeding hopper 501, a material pushing opening 503, a feeding arm 504, a slope 505, a restraining edge 506, a detection channel opening 507, a material outlet 508, a feeding channel 509, and a limiting plate 510. In actual application, as shown in fig. 4, the detection cards are stacked and placed in the feed hopper in the order of the detection area above and the sample application area below, after the automatic detection system is started, the motor starts to work, the feed arm 504 advances toward the detection channel opening 507, the detection card at the lowest layer is pushed out by the feed arm, the feed arm then retracts in the opposite direction of the detection channel opening 507, the detection card at the upper layer slides down to the original position of the detection card pushed out, the feed arm advances again, the detection card is pushed out again, the feed arm continuously and circularly retracts and pushes out along the detection channel opening, the detection card is continuously pushed out, when the first pushed detection card reaches the inclined plane 505, the restraining edge 506 of the detection channel opening 507 retracts inwards to restrain the displacement of the detection card in the horizontal direction, the restraining edge 506 restrains the displacement of the detection card in the vertical direction by the restraining plate 510, the restraining edge 506 and the feed channel 509, the restraining edge, The limiting plate 510 forms a limiting cavity together, the cavity acts on the detection cards in the horizontal direction and the vertical direction, so that the tenon structure and the mortise structure on each detection card are tightly fitted, as shown in fig. 6, the fitted detection card combination is obtained, the detection card combination enters the sample adding test area of the system through the transmission device after reaching the detection channel opening 507, the feeding arm automatically stops feeding at the moment, and when the whole row of detection card combination is taken away by the transmission device, the feeding arm starts feeding again for a new round.
Example 2
As shown in fig. 5, the detection card of the present invention includes a detection card 400, a detection region 401, a sample addition region 402, a tenon structure 403, a mortise structure 404, a tenon structure 405, a mortise structure 406, a detection card right side 407, a detection card left side 408, a detection card upper side 409, a detection card bottom plate 410, and a line 412 formed by overlapping the upper case and the bottom plate. As shown in fig. 1 and fig. 2, the feeding device is a perspective view, and the feeding device includes a feeding hopper 501, a material pushing opening 503, a feeding arm 504, a slant surface 505, a restraining edge 506, a detection channel opening 507, a material outlet 508, a feeding channel 509, and a limiting plate 510. In practical application, a plurality of feeding devices are arranged in a full-automatic lateral chromatography detection system, a plurality of detection cards are arranged in a stacking manner in a feeding hopper according to the sequence that the detection area is on the upper side and the sample application area is on the lower side, after the automatic detection system is started, a motor starts to work, a plurality of parallel feeding devices simultaneously operate, a feeding arm 504 is pushed towards a detection channel opening 507, the detection card at the lowest layer is pushed out by the feeding arm, then the feeding arm is withdrawn towards the opposite direction of the detection channel opening 507, the detection card at the upper layer slides downwards to the original position of the pushed detection card, the feeding arm is pushed again, the detection card is pushed out again, the feeding arm continuously and circularly retracts and pushes out along the direction of the detection channel opening, the detection card is continuously pushed out, when the first pushed detection card reaches the inclined plane 505, a restraining edge 506 of the detection channel opening 507 contracts inwards to restrain, and limits the displacement of the detection card in the horizontal direction, the limiting plate 510 limits the displacement of the detection cards in the vertical direction, so that the tenon structure 403 and the mortise structure 404 on each detection card are tightly fitted to obtain a tenon-and-mortise structure, the detection card assembly is taken away through the transmission device after reaching the detection channel opening 507, the feeding arm automatically stops feeding at the moment, and when the whole row of detection card assemblies are taken away by the transmission device, the feeding arm starts feeding again. The plurality of parallel detection card assemblies are brought away by the transmission device and then are close to the middle, at the moment, the plurality of tenon structures 405 and the mortise structures 406 on the detection card assemblies are tightly fit to obtain the detection card assemblies shown in figure 7, and then the transmission device brings the detection card assemblies into a sample adding test area of the system.
The foregoing detailed description is intended to illustrate and not limit the invention, which is intended to be within the spirit and scope of the appended claims, and any changes and modifications that fall within the true spirit and scope of the invention are intended to be covered by the following claims.
Claims (10)
1. A feeding device of a full-automatic lateral chromatography detection system comprises a transverse feeding channel (509) and a detection channel opening (507), and a feeding hopper (501) vertically arranged on the detection channel (507), wherein a material pushing opening (503) for feeding and discharging a feeding arm (504) and a material discharging opening (508) facing the detection channel opening (507) are arranged below the feeding hopper (501), and the feeding device is characterized in that a plurality of immune lateral chromatography detection cards are arranged in the feeding hopper (501); the immune lateral chromatography detection card comprises a sample adding area, a detection area and at least one connecting area, wherein the connecting area is provided with at least one tenon structure (203; 403) and at least one mortise structure (204; 404); the sample adding area and the detection area are arranged on a first plane of the detection card, and the tenon structure (203; 403) and the mortise structure (204;
404) Are respectively positioned at two sides of the first plane; the two sides of the feed hopper (501) are connected with the tenon structures (203;
403) and a mortise structure (204; 404) the corresponding position forms a clamping surface.
2. The feeding device of the fully automatic lateral flow assay system as claimed in claim 1, wherein one or both sides of the feeding channel (509) are provided with a slant (505) for facilitating the entry of the immuno-lateral flow assay card into the detection channel opening (507).
3. The feeding device of the fully automatic lateral chromatography detection system according to claim 1, wherein the detection channel opening (507) is provided with a limiting plate (510) inclined upwards.
4. The feeding device of the fully automatic lateral flow assay system according to claim 2 or 3, wherein the inclined surfaces (505, 506) of the feeding channel (509) are provided with a restricting edge (506) towards the direction of the detection channel opening (507), and the restricting edge (506), the limiting plate (510) and the feeding channel (509) together form a limiting cavity.
5. The feeding device of the fully automatic lateral chromatography detection system according to claim 1, wherein any two parallel planes of the feeding hopper (501) can be opened outwards in the horizontal direction and can also be clamped inwards in the horizontal direction.
6. The feeding device of the fully automatic lateral chromatography detection system according to claim 1, wherein the tenon structure (405) and the mortise structure (406) are disposed on the other two sides of the first plane.
7. The feeding device of the full-automatic lateral chromatography detection system according to claim 1, wherein the plurality of detection cards are connected into a mortise and tenon structure (207; 411) through a mortise and tenon structure.
8. the feeding device of the full-automatic lateral chromatography detection system according to claim 1, wherein the tenon structure and the mortise structure of the connecting area protrude out of the side surface of the detection card, and the mortise structure is recessed into the side surface of the detection card.
9. The feeding device of the full-automatic lateral chromatography detection system according to claim 1, wherein the tenon structure and the mortise structure have the same shape and structure, and the tenon structure and the mortise structure are symmetrical with each other with respect to the detection region and the sample addition region.
10. The feeding device of the full-automatic lateral chromatography detection system according to claim 1, wherein the cross section of the tenon structure and the mortise structure is rectangular or the cross section is polygonal; the width of the tenon structure and the mortise structure is equal to or less than that of the side face.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810557852.9A CN110554185A (en) | 2018-06-01 | 2018-06-01 | Feeding device of full-automatic lateral chromatography detection system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810557852.9A CN110554185A (en) | 2018-06-01 | 2018-06-01 | Feeding device of full-automatic lateral chromatography detection system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110554185A true CN110554185A (en) | 2019-12-10 |
Family
ID=68734811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810557852.9A Pending CN110554185A (en) | 2018-06-01 | 2018-06-01 | Feeding device of full-automatic lateral chromatography detection system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110554185A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111678792A (en) * | 2020-06-17 | 2020-09-18 | 重庆工程职业技术学院 | Building material strength detection device |
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| CN106706937A (en) * | 2017-02-05 | 2017-05-24 | 深圳市活水床旁诊断仪器有限公司 | Quasi-automatic immunity analyzer and detecting method |
| CN206960475U (en) * | 2017-04-20 | 2018-02-02 | 深圳市中核海得威生物科技有限公司 | A kind of helicobacter pylori tester |
| CN207148134U (en) * | 2017-09-27 | 2018-03-27 | 深圳无微华斯生物科技有限公司 | A kind of full-automatic fluorescence detecting system and fluorescence immune chromatography readout instrument |
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2018
- 2018-06-01 CN CN201810557852.9A patent/CN110554185A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202757946U (en) * | 2012-08-16 | 2013-02-27 | 山东凯胜电子股份有限公司 | Compressing device for full-automatic intelligent card module detecting device |
| CN203551568U (en) * | 2013-11-04 | 2014-04-16 | 无锡博慧斯生物医药科技有限公司 | Dismountable and mountable detecting card slot |
| WO2015096767A1 (en) * | 2013-12-26 | 2015-07-02 | 杭州中翰盛泰生物技术有限公司 | Full-automatic instant check meter |
| CN105044336A (en) * | 2015-07-25 | 2015-11-11 | 中山瑞福医疗器械科技有限公司 | Multi-channel detecting instrument |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111678792A (en) * | 2020-06-17 | 2020-09-18 | 重庆工程职业技术学院 | Building material strength detection device |
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Address after: 2 / F, building 2, 146 Chaofeng East Road, Yuhang Economic and Technological Development Zone, Hangzhou, Zhejiang 310000 Applicant after: Hangzhou Weice Biotechnology Co.,Ltd. Address before: 2 / F, building 2, 146 Chaofeng East Road, Yuhang Economic and Technological Development Zone, Hangzhou, Zhejiang 310000 Applicant before: VivaChek Biotech (Hangzhou) Co.,Ltd. |