CN110531068A - A kind of animal epidemic colloidal-gold detecting-card - Google Patents
A kind of animal epidemic colloidal-gold detecting-card Download PDFInfo
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- CN110531068A CN110531068A CN201910845832.6A CN201910845832A CN110531068A CN 110531068 A CN110531068 A CN 110531068A CN 201910845832 A CN201910845832 A CN 201910845832A CN 110531068 A CN110531068 A CN 110531068A
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- lower case
- valve block
- shim
- colloidal
- tube
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
Abstract
The present invention relates to a kind of animal epidemic colloidal-gold detecting-cards, belong to detection technique field.Animal epidemic colloidal-gold detecting-card of the invention includes shell, shell includes upper housing and lower case, lower case includes lower case bottom plate, there are two the opposite closing U-tubes that is open for the fixed setting of lower case plate upper surface, U-tube includes two along the longitudinal pipe of lower case length direction extension and the transverse pipe extended along lower case width direction, and the both ends of transverse pipe are wholely set and are interconnected with the corresponding end of two longitudinal pipes respectively；The longitudinal pipe and transverse pipe of two U-tubes define the test paper slot for accommodating test strips；Separator valve is provided in the transverse pipe of U-tube, the U-tube internal cavities are divided into two cavitys by separator valve, and two cavitys are respectively intended to can produce two kinds of liquid of heat after receiving mixes.Two U-tubes of the invention can heat in the space to the receiving test strips that it is surrounded, and heat is not allowed easy to lose, and heating effect is more preferable.
Description
Technical field
The present invention relates to a kind of animal epidemic colloidal-gold detecting-cards, belong to detection technique field.
Background technique
Colloidal-gold detecting-card is that especially had in animal epidemic detection field using a kind of very extensive detection instrument
Good detection effect.When animal epidemics are broken out, quickly whether the cultivated animal of judgement infects epidemic disease, mostly moves on a large scale
Object has infected epidemic disease, most important for raiser.Due to growing day by day, the animal epidemics outburst of animal-breeding quantity
Afterwards, propagation is very fast, as African swine fever, porcine pseudorabies, pig blue-ear disease etc..In Epidemic outbreak of disease, carried out using detection card
The features such as detection has speed fast, at low cost, easy to operate.Detection card, which generally comprises, gets stuck and is arranged in the test strips in getting stuck,
It gets stuck and generally comprises upper housing and lower case, well, observation window are provided on upper housing, be respectively intended to fill in test strips
The color change of detection line and nature controlling line on sample to be tested, observation test strips.
The detecting state of current colloidal-gold detecting-card is highly susceptible to the influence of environment temperature and humidity, causes to detect
Unstable result, inaccuracy.Colloidal-gold detecting-card when especially for animal detection, largely requires to examine outdoors
It surveys, when environment temperature is too low or humidity is excessive, it is easy to cause testing result inaccurate.
Summary of the invention
The present invention provides a kind of animal epidemic colloidal-gold detecting-card, to weaken environment temperature to the shadow of colloidal-gold detecting-card
It rings.
It is as follows that the present invention solves technical solution used by above-mentioned technical problem:
A kind of animal epidemic colloidal-gold detecting-card, the test strips including shell and setting in the housing, the shell packet
Include mutually matched upper housing and lower case, the lower case includes lower case bottom plate and is fixed at lower case bottom plate side
The lower case flange of edge, there are two the opposite closing U-tube that is open, the U-tube packets for the fixed setting of lower case plate upper surface
Two are included along the longitudinal pipe of lower case length direction extension and the transverse pipe extended along lower case width direction, the both ends of transverse pipe
It is wholely set and is interconnected with the corresponding end of two longitudinal pipes respectively；The longitudinal pipe and transverse pipe of two U-tubes define use
To accommodate the test paper slot of test strips；Separator valve is provided in the transverse pipe of the U-tube, the separator valve will be in the U-tube
Portion's cavity is divided into the first cavity and the second cavity, and first cavity and the second cavity are respectively intended to produce after accommodating mixing
The first liquid and second liquid of heat amount；The separator valve includes the first shim that parallel interval is fixedly installed and second point
Partition, being folded between the first shim and the second shim can be in the valve block mobile perpendicular to lateral tube axis direction；First
The first fluid hole and the second fluid hole are respectively arranged on shim and the second shim, the first fluid hole and the second fluid hole are same
Axis is arranged and communicates respectively with the first cavity and the second cavity；It is provided with valve opening on valve block, makes valve opening and when valve block is moved to
When the position of one fluid hole and the second fluid hole is corresponding, the liquid of the first cavity and second chamber body can be mutually mixed.
The opposite closing U-tube of the opening is two end-encloseds of the longitudinal pipe far from transverse pipe of each U-tube,
The U-shaped opening of two U-tubes is oppositely arranged.The transverse pipe of two U-tubes is arranged close to the both ends of lower case bottom plate.Lower case is convex
The edge that lower case bottom plate is arranged in edge refers to that the upper surface of lower case bottom plate is solid close to the position of lower case bottom plate peripheral side
The lower case flange is set surely, and the outer peripheral surface of lower case flange is concordant with lower case bottom plate outer peripheral surface.Lower case flange is ring
Shape structure.
Thermally conductive sheet is provided on the upper surface of the lower case bottom plate, the thermally conductive sheet upper surface fixed setting is described U-shaped
Pipe, the lower surface of the U-tube is bonded setting with the thermally conductive sheet upper surface.It is further preferred that the thermally conductive sheet upper surface
On be provided with made of non-good heat conducting material, the support frame for supporting test strips.
The thermally conductive sheet is sheet metal, graphite paper, any one in graphene film.
The valve block includes valve block ontology and the push-and-pull portion being fixedly linked with valve block ontology, and push-and-pull portion upper end, which has, to be used
To apply thrust so that the pushing tow face that valve block moves down to valve block.
The valve block includes valve block ontology and the push-and-pull portion being fixedly linked with valve block ontology, and the push-and-pull portion is in transverse pipe axis
The thickness in line direction is greater than the distance between the first shim and the second shim.
Upper housing includes upper housing bottom plate and the upper housing flange for being fixed at upper housing bottom edge, the upper casing
Body bottom plate position corresponding with the separator valve in transverse pipe is provided with handle hole, and the push-and-pull portion is inserted into the handle hole.
The push-and-pull portion is arranged fluted on two sides of transversely tube axis direction.
The push-and-pull portion is in the thickness for being not more than upper housing bottom plate perpendicular to the height on upper housing bottom plate direction.
Positioning protrusion/positioning groove is provided on the valve block, it is fixed to be provided on the first shim and/or the second shim
Position groove/positioning protrusion, positioning protrusion and positioning groove cooperate to limit valve block perpendicular to the shifting on lateral tube axis direction
It is dynamic.
Positioning groove/the positioning protrusion being arranged on first shim and/or the second shim is two groups, vertically side
It is arranged to interval, each group of positioning groove/positioning protrusion quantity and the positioning protrusion on valve block/positioning groove quantity phase
Deng；Positioning protrusion/positioning groove and the first shim on the valve block and/or two groups of positioning grooves on the second shim/
When one group of engaging in positioning protrusion, separator valve is in closed state, and when engaging with another group, separator valve is in the open state.
The upper housing upper surface is provided with temperature indicating device.
Position corresponding with test strips is provided with air flow passage on the thermally conductive sheet.
The upper housing includes upper housing bottom plate and the upper housing flange for being fixed at upper housing bottom edge, described
Height of the U-tube on the direction perpendicular to lower case bottom plate is equal to the sum of lower case flange and the height of upper housing flange.On
Well, observation window are provided on shell.
First liquid is selected from least one of acetum, hydrochloric acid solution, oxalic acid solution, and second liquid is selected from sodium carbonate
At least one of solution, sodium hydroxide solution, calcium hydroxide solution.Or first liquid and second liquid be respectively water and wine
Essence.Test strips include bottom plate, pass through on bottom plate and are disposed with sample pad, label pad, nitrocellulose filter, suction
Water cushion.One end of sample pad is overlapped on one end of label pad, and the other end of label pad is overlapped on one end of nitrocellulose filter, nitre
The other end of acid cellulose film is overlapped on one end of water absorption pad.Detection line and nature controlling line are provided on nitrocellulose filter.
Beneficial effects of the present invention:
Two U-tubes, two U-tubes are arranged in animal epidemic colloidal-gold detecting-card of the invention on the upper surface of lower case
It is oppositely arranged, defines the space for accommodating test strips.U-tube can be contained two kinds in two cavitys that separator valve separates respectively
Different liquid, both liquid can generate heat upon mixing, can be to space behind the space that heat transfer to U-tube surrounds
Interior gas is heated, and on the one hand guarantees that temperature of the test strips in test will not be too low, on the other hand when in upper and lower shell body
Air humidity it is too big when, be also beneficial to after heating reduce humidity, guarantee test strips be in suitable test condition.Two U
Type pipe can heat in the space to the receiving test strips that it is surrounded, and heat is not allowed easy to lose, and heating effect is more preferable.
Detailed description of the invention
Fig. 1 is the lower case structural schematic diagram of animal epidemic colloidal-gold detecting-card of the invention；
Fig. 2 is the front view of the lower case of animal epidemic colloidal-gold detecting-card of the invention；
Fig. 3 is the cross-sectional view in the direction A-A in Fig. 2；
Fig. 4 is the enlarged drawing in Fig. 3 at B；
Fig. 5 is the structural schematic diagram of the U-tube of animal epidemic colloidal-gold detecting-card of the invention；
Fig. 6 is the front view of the U-tube of animal epidemic colloidal-gold detecting-card of the invention；
Fig. 7 is the cross-sectional view in the direction C-C in Fig. 6；
Fig. 8 is the separator valve valve structure schematic diagram in the U-tube of animal epidemic colloidal-gold detecting-card of the invention；
Fig. 9 is the structural schematic diagram of animal epidemic colloidal-gold detecting-card of the invention.
Specific embodiment
In order to be easier to understand the technical problems, technical solutions and beneficial effects solved by the present invention, below with reference to tool
The present invention is described in detail for body embodiment.
As shown in figs. 1-9, animal epidemic colloidal-gold detecting-card of the invention includes shell, is provided with test strips in shell
(being not drawn into figure).Shell includes mutually matched upper housing 1 and lower case 2, shape after upper housing and lower case are mutually clamped
At the shell of detection card.
Upper housing 1 includes upper housing bottom plate, and upper housing bottom plate is the cuboid that fillet is arranged in quadrangle, upper housing bottom plate
Lower surface (towards the one side of lower case) surrounding is provided with upper housing flange 101, and upper housing flange is around one Monday of upper housing bottom plate
Body is arranged on upper housing lower surface, identical as the shape of upper housing bottom plate.
Lower case 2 includes lower case bottom plate, and lower case bottom plate is the cuboid that fillet is arranged in quadrangle, with upper housing bottom plate
Shape it is identical with size, upper surface (towards the one side of upper housing) surrounding of lower case bottom plate is provided with lower case flange 201,
Lower case flange was integrally disposed upon on lower case upper surface around lower case bottom plate one week, the periphery of circumference and lower case bottom plate
Shape is identical.
There are two U-tubes 202 for setting on lower case plate upper surface, and U-tube is square tube (cross section is rectangle), each
Two end seals of U-tube are arranged, and the U-shaped opening of two U-tubes is oppositely arranged.U-tube is in above-below direction (i.e. perpendicular under
The direction of Housing Base) height be equal to upper housing flange and lower case flange 201 in the sum of the height of the direction.
As shown in Figure 5 and Figure 6, each U-tube includes that two length directions along lower case extend and disposed in parallel vertical
To pipe 2021 and a transverse pipe 2022 extended along lower case width direction, two transverse pipes 2022 are respectively close to lower case bottom
The both ends of plate, the both ends of the transverse pipe 2022 of each U-tube are fixed with the end of corresponding two longitudinal pipes 2021 respectively to be connected
It connects, setting is integrated in the present embodiment.In this way, the correspondence side wall of two U-tubes being oppositely arranged and the upper surface of lower case are total
With a groove is defined, which is used to accommodate and fix test strips, and the width of groove is equal to or slightly greater than test strips
The length of width, groove is equal to or slightly greater than the length of test strips, prevents test strips from moving in the horizontal direction.
The lower surface of each U-tube, i.e., the lower surface of two longitudinal pipes and the lower surface of transverse pipe, welding or bonding
It is arranged on the upper surface of lower case bottom plate.Upper housing and lower case and U-tube are all made of plastic injection and are formed, under U-tube
Surface is bonded and fixed on lower case upper surface by sweat soldering or by a very thin layer binder.
A separator valve 203 is both provided in each U-tube, separator valve 203 is arranged in the transverse pipe of U-tube, excellent
Bit selecting is set to one end that transverse pipe 2022 is arranged in close to the position of a longitudinal pipe 2021, so that on upper-lower casing with
The corresponding position of separator valve 203 is also at the side of length direction in upper housing or lower case.In other embodiments, separate
The position of valve may be at the middle part of transverse pipe.
The entire inner cavity of U-tube including transverse pipe 2022 and longitudinal pipe 2021 is divided into two by separator valve 203
Cavity.Separator valve includes two shims and valve block 2031 perpendicular to the setting of lateral tube axis direction, and two shims are parallel
Interval setting, valve block 2031 are folded between two shims.
Transverse pipe 2022 can be contained two different liquid in two cavitys that separator valve 203 separates respectively, this two
Kind of liquid can generate heat upon mixing, can be to the gas in space behind the space in the groove of heat transfer to fixation test strips
Body is heated, and on the one hand guarantees that temperature of the test strips in test will not be too low, on the other hand when the air in upper and lower shell body
Humidity it is too big when, be also beneficial to after heating reduce humidity, guarantee test strips be in suitable test condition.
The liquid filled in two cavitys can be the solution of soda acid type, as acetic acid and sodium carbonate, hydrochloric acid and sodium hydroxide,
The solution of oxalic acid and calcium hydroxide etc., is also possible to the liquid of mild, such as water and alcohol.Preferably water and alcohol.
For the ease of the filling liquid into pipe, transverse pipe 2022 or coupled 2021 upper surface of longitudinal pipe and two
The corresponding position of cavity is respectively arranged with liquid filling hole (not regarding out) and the liquid feeding plug sealed with liquid filling hole cooperation to liquid filling hole (not
Depending on out).After injecting suitable liquid by liquid filling hole, fluid seepage will be avoided on liquid feeding plug plug to liquid filling hole.It can also be direct
Liquid feeding plug is welded on liquid filling hole.
In the present embodiment, transverse pipe 2022 is provided with a side on the upper surface of one end of a longitudinal pipe 2021
Shape blind hole 2032, it is opening up.Rectangular blind hole section in the horizontal direction is rectangle, in four inner sidewalls of rectangular blind hole,
Two opposite inner sidewalls are parallel to lateral tube axis direction setting, other two opposite inner sidewall is perpendicular to transverse pipe axis
Direction setting.Be parallel to two inner sidewalls being oppositely arranged of horizontal line tube axis direction wall thickness (i.e. some interior side-wall surface with
The distance between its corresponding transverse pipe outer side wall surface) it is equal to the pipe thickness of transverse pipe.Perpendicular to the two of transverse pipe axis
The wall thickness of a inner sidewall is also equal to the pipe thickness of transverse pipe, constitutes separator valve perpendicular to two inner sidewalls of horizontal line pipe axis
Two shims, be folded with valve block 2031 between two shims.The wall thickness of the bottom wall of rectangular blind hole is also equal to transverse pipe
Pipe thickness.
As shown in figure 8, valve block 2031 includes valve block ontology 20311 and the push-and-pull portion 20312 being fixedly linked with valve block ontology,
The two integrated injection molding.Valve block ontology 20311 be plate (cuboid) structure, the height of valve block ontology up and down direction with it is above-mentioned
The deep equality of rectangular blind hole or the depth for being slightly less than rectangular blind hole.Valve block ontology is in the level side perpendicular to transverse pipe axis
Upward width width equal or slightly larger than rectangular jack with the width of above-mentioned rectangular blind hole, rectangular blind hole perpendicular to cross
The distance between two inner sidewalls to pipe axis are equal to or slightly less than the thickness in this direction of valve block ontology, so that valve
Piece ontology can fit closely after being inserted into rectangular blind hole with four inner sidewalls of rectangular blind hole, form liquid sealing.
It is provided with the valve opening 20313 for running through throttle slice thickness on valve block 2031, is round hole.Rectangular blind hole perpendicular to
It is respectively arranged with a fluid hole on two inner sidewalls of transverse pipe axis, the size shape of fluid hole is identical as valve opening.It is each
A fluid hole all runs through the thickness of corresponding inner sidewall, communicates with the inner chamber body of corresponding transverse pipe.Two fluid holes are coaxially set
It sets, and axis is parallel to transverse pipe axis.When valve block ontology is fully inserted into rectangular blind hole, two fluid holes and valve opening are just wrong
Two fluid holes are blocked in open position, the part that valve block ontology is not provided with valve opening, avoid the intracorporal liquid of corresponding two chambers
Body is flowed out from fluid hole.When drawing that valve block ontology is outside, valve block ontology can be moved to just makes valve opening and fluid hole
Coaxially, at this moment two intracorporal liquid of chamber mutually mix, and generate heat.
The top surface (i.e. upper surface) in push-and-pull portion 20312 is constituted for the pushing tow face that pushing tow valve block moves down it.When
When not needing too many heat, can by valve block ontology into rectangular blind hole pushing tow, make valve opening deviate two fluid holes position, from
And sealed two fluid holes using valve block ontology, avoid two intracorporal liquid of chamber from continuing contact mixing.Due to separator valve
The volume of all parts is very small, and in order to facilitate pushing tow valve block, pushing tow groove is additionally provided on the top surface in push-and-pull portion 20312
20314, pushing tow groove 20314 is extended along perpendicular to lateral tube axis direction, and runs through the top surface in entire push-and-pull portion.It uses
When, pushing tow can be carried out using nail or sharp instruments.
In order to facilitate drawing valve block, at least one of two sides perpendicular to transverse pipe axis in push-and-pull portion 20312
It is also equipped with drawing groove 20315, drawing groove 20315 is extended along the direction perpendicular to transverse pipe, and through corresponding
The side in push-and-pull portion.It is provided with drawing groove on two sides in the present embodiment, in use, the nail of two fingers can be used
It clamps push-and-pull portion and extracts valve block outward.
Push-and-pull portion 20312 is being greater than the width of valve block ontology in this direction perpendicular to the length on lateral tube axis direction
It spends, in the present embodiment, the length of push-and-pull portion in this direction is equal with the width of transverse pipe in this direction, wider than valve block ontology
The length for having spent two lateral tube thickness big.The part that the both ends of push-and-pull portion length direction grow valve block ontology forms push-and-pull portion
Block end.In this way, push-and-pull portion is also unlikely to enter rectangular when the length that valve block ontology is arranged is less than the depth of rectangular blind hole
Blind hole and drawing does not go out.For further block push-and-pull portion, width of the push-and-pull portion on lateral tube axis direction is greater than valve block and exists
Thickness in this direction, in this way setting also help more convenient when manual drawing push-and-pull portion.
In order to avoid valve block ontology is pulled out rectangular blind hole, liquid leakage is caused, in the two side walls of valve block ontology
It is provided with a positioning protrusion 20316, and in each of the two side walls perpendicular to transverse pipe axis of corresponding rectangular blind hole
Two positioning grooves are all set on a, and two positioning grooves are arranged along rectangular blind hole depth direction interval.When convex card lifting is set
When in that positioning groove close to rectangular blind hole bottom surface, valve opening and the complete staggered positions of fluid hole, i.e. the closing of separator valve
State.When pulling push-and-pull portion, so that valve block ontology is moved outwardly to that positioning protrusion is fastened on far from rectangular blind hole bottom surface and determine
When in the groove of position, valve opening and fluid hole are coaxial, i.e. the opening state of separator valve.At this moment since positioning protrusion and positioning groove are mutual
Card is set, and also avoids valve block ontology pulling out rectangular blind hole.
As shown in figure 9, well 102, observation window 103 are provided on upper housing bottom plate, under well 102 is substantially gone up greatly
The small shape of falling elliptical cone, observation window 103 are generally rectangular.The rectangular blind hole of this implementation it is opening up, it is matched
, position corresponding with the rectangular blind hole is provided with handle hole 104 on upper housing bottom plate, enable the push-and-pull portion of valve block 2031 from
It is stretched out in handle hole, facilitates drawing.In order to facilitate the push-and-pull portion of protection valve block, maloperation is avoided, the thickness in valve block push-and-pull portion is not
Greater than the thickness of upper housing bottom plate, in the present embodiment, the two is equal.The size of handle hole is greater than the size in push-and-pull portion, specifically,
On horizontal line tube axis direction, the width of handle hole is greater than the width in push-and-pull portion, and it is empty to leave sufficient operation to drawing push-and-pull portion
Between.Further, handle hole is set as diminishing throat structure from top to bottom, in order to which finger is operated.
In order to sufficiently avoid valve block from being drawn out rectangular blind hole, the lower end edge valve block body width direction of valve block ontology extends
Two sides be provided with limited post, it is corresponding, be provided with limit on two inner sidewalls that rectangular blind hole is parallel to transverse pipe axis
Slot, two limited posts are inserted into corresponding limiting slot, can slide up and down in limiting slot.Limiting slot is along perpendicular to transverse pipe axis
The length in line direction is less than the depth of rectangular blind hole, is drawn out to avoid valve block.Further, limiting slot is along perpendicular to transverse pipe
The length of axis direction is less than the half of the depth of rectangular blind hole.
Width and transverse pipe of the longitudinal pipe of U-tube on lower case baseplate width direction are in lower case floor length direction
Width it is equal, be not less than U-tube (transverse pipe and longitudinal pipe) height, it is preferred that the width be equal to U-tube height 1-
2 times.Further preferably 1.3 times.
It is solid that position on 2 plate upper surface of lower case close to lower case flange also sets up that there are four the cylinders that are spaced apart
Fixed column 204, perpendicular to lower case bottom plate, each fixed column is provided centrally with along the extension of its axis direction the axis of fixed column
Fixation hole.Position corresponding with the fixation hole of each fixed column is provided with cylindrical fixed arm on the lower surface of 1 bottom plate of upper housing.
The outer diameter of fixed arm is equal with the internal diameter of fixation hole in the fixed column of lower case or the outer diameter of fixed arm is slightly larger than fixation hole
Internal diameter.Fixed arm is being slightly less than fixation hole perpendicular to lower case bottom plate direction perpendicular to the height on upper housing bottom plate direction
On depth.
Fixation hole on fixed arm and lower case cooperates, and fixed arm is inserted into the fixation hole of the fixed column in lower case
In, so that upper housing is fastened with lower case by frictional force between the two together with.
Upper housing 1 and lower case 2 are all made of plastics integrated injection molding and are formed, when the fixed arm insertion lower case on upper housing
When in the fixation hole in fixed column, upper and lower casing can be rigidly secured together by frictional force between the two.
When detection card assembling, the valve block of each U-tube is mounted in the rectangular blind hole in transverse pipe, in closing
Liquid injection hole is closed in the fluid injection of separator valve two sides in position.Liquid is poured in by two and the U-tube sealed is bonded on lower case bottom plate
On surface, test strips are then placed, upper housing is buckled in lower case, assembling can be completed.In use, push-and-pull portion is outside
Drawing is fastened on the positioning protrusion on valve block ontology in the outer positioning groove on rectangular blind hole side wall, realizes valve opening
Unlatching.The liquid mixing heat release made in two cavitys of each U-tube is rocked along shell length direction, it is uniform to temperature
Afterwards, it can be detected.
U-tube can be processed by the way of integrated injection molding, can also be used and be processed into two sections of pipes open at one end,
Then the open end of pipe open at one end and separator valve are bonded or are welded together by individually processing separator valve.Certainly
Two sections of pipes can also be processed into sealing two ends, then pipe is corresponded to the end face of one end and two shims difference of separator valve
Bonding or welding.Other parts processing modes, such as two shims of separator valve in the prior art can also be taken
Individually processing, is then bonding or is welding together, it is only necessary to reserve spacing distance between two shims.
Further, the position for U-tube being arranged on lower case plate upper surface is provided with thermally conductive sheet 205.Thermally conductive sheet can
To be set as a piece of, two U-tubes are opposite, are arranged on thermally conductive sheet upper surface.Thermally conductive sheet 205 may be set to be two panels with
On, it is arranged along lower case floor length direction interval.Thermally conductive sheet can be continuously arranged for full wafer, can also be arranged on thermally conductive sheet
Mesh, or setting long hole or elongated slot.Thermally conductive sheet can also be set to herringbone form, including a leading torrid zone, dominate heat
Two or more branch thermal conductive belts are provided with two sides, branch thermal conductive belt one end is fixedly connected with the leading torrid zone, and the other end prolongs to two sides
It stretches.Parallel interval is arranged between branch thermal conductive belt.Test strips support frame 206, support frame 206 can also be set on thermally conductive sheet upper surface
It is less than the height of U-tube in this direction in the height perpendicular to lower case base plate thickness direction.It may be set to be, support frame
Thermally conductive sheet is arranged in the position of surrounding, and support frame is directly anchored on the upper surface of lower case bottom plate.Thermally conductive sheet is sheet metal, graphite
Any one in paper, graphene film, sheet metal is copper foil or aluminium foil, with a thickness of 10 μm or so.In other embodiments,
It can be not provided with thermally conductive sheet, and support frame is only set.Thermally conductive sheet can certainly be only set and be not provided with support frame or the two all
It is not provided with.
As different embodiments, U-tube can also be fixed in the following way: in U-tube upper and lower surface
U-tube fixed column is provided at least one, U-tube fixed column is cylinder, and axis is perpendicular to U-tube upper and lower surface.Upper casing
The lower surface of body and the corresponding position of U-tube are provided with cylindrical U-tube corresponding with the fixed column on U-tube upper surface and fix
Hole.The quantity of U-tube fixed column and U-tube fixed column can be optionally arranged, in general, on U-tube upper surface or lower surface
U-tube fixed column quantity all at three or more.
As different embodiments, opening up square groove is offered on the transverse pipe upper surface of U-tube, it is rectangular
Bottom portion of groove is provided with opening up rectangular jack, the sum of depth of the depth of rectangular jack and square groove and above-mentioned implementation
The depth of rectangular blind hole is identical in example, in addition to this, the structure phase of the structure of rectangular jack with blind hole rectangular in above-described embodiment
Seemingly.Two side walls perpendicular to transverse pipe axis of rectangular jack constitute two above-mentioned shims, unlike, convex
It rises and positioning groove is arranged on the corresponding side of square groove inner sidewall and push-and-pull portion.Valve block includes valve block ontology and and valve block
The push-and-pull portion that ontology is fixedly linked, the two integrated injection molding.Valve block ontology be rectangular parallelepiped structure, the height of valve block ontology with it is upper
State rectangular jack height is equal or height slightly larger than rectangular jack, the width of the width of valve block ontology and above-mentioned rectangular jack
Spend width equal or slightly larger than rectangular jack.After valve block ontology is inserted into rectangular jack, the outer wall of valve block ontology can be made
It is fitted closely between the inner wall of rectangular jack, forms liquid sealing.The push-and-pull portion of valve block be rectangular parallelepiped structure, pushing tow lid perpendicular to
The setting of valve block ontology, the two " T " shape structure on the whole.The height in push-and-pull portion and the height of square groove are equal, and push-and-pull portion exists
Perpendicular to the equal length in this direction of length and square groove on the direction of valve block ontology.Push-and-pull portion is perpendicular to cross
It is less than the depth of square groove in this direction to the thickness of tube axis direction.Preferably, the thickness of pushing tow lid is equal to rectangular recessed
The half of groove depth.Locating slot is provided in the two side walls of square groove, locating slot is two groups, along the depth side of square groove
To setting gradually.Each group of locating slot includes two positioning grooves, and positioning groove is spherical groove.It is corresponding, in push-and-pull portion
The positioning protrusion equal with positioning slot number is provided on side wall, positioning protrusion is fastened in corresponding positioning groove, Neng Gougu
The position of fixed valve plate.The position of this two groups of locating slots has respectively constituted open position and the closing position of valve block.
As different embodiments, surveyed when being in suitable temperature for the air themperature between upper and lower casing
Examination, can be arranged shallower paster groove on upper housing surface, and temperature patch is sticked in paster groove.Three lattice can be used in temperature patch
Or five lattice temperature display bars, be the suitable temperature tested in intermediate one.
Claims (10)
1. a kind of animal epidemic colloidal-gold detecting-card, the test strips including shell and setting in the housing, the shell include
Mutually matched upper housing and lower case, which is characterized in that the lower case includes lower case bottom plate and is fixed at down
The lower case flange at Housing Base edge, there are two the opposite closing U-tube that is open, institutes for the fixed setting of lower case plate upper surface
Stating U-tube includes two along the longitudinal pipe of lower case length direction extension and the transverse pipe extended along lower case width direction, horizontal
It is wholely set and is interconnected with the corresponding end of two longitudinal pipes respectively to the both ends of pipe；The longitudinal pipe and transverse direction of two U-tubes
Pipe defines the test paper slot for accommodating test strips；
Separator valve is provided in the transverse pipe of the U-tube, the U-tube internal cavities are divided into the first chamber by the separator valve
Body and the second cavity, first cavity and the second cavity be respectively intended to accommodate mixing after can produce heat the first liquid and
Second liquid；The separator valve include parallel interval fixed setting the first shim and the second shim, the first shim and
Being folded between second shim can be in the valve block mobile perpendicular to lateral tube axis direction；First shim and the second shim
On be respectively arranged with the first fluid hole and the second fluid hole, the first fluid hole and the coaxial arrangement of the second fluid hole and respectively with first
Cavity and the second cavity communicate；It is provided with valve opening on valve block, so that valve opening and the first fluid hole and second is gone out liquid when valve block is moved to
When the position in hole is corresponding, the liquid of the first cavity and second chamber body can be mutually mixed.
2. animal epidemic colloidal-gold detecting-card according to claim 1, which is characterized in that the upper table of the lower case bottom plate
Thermally conductive sheet is provided on face, the U-tube is fixedly installed in the thermally conductive sheet upper surface, and the lower surface of the U-tube is led with described
The fitting setting of backing upper surface.
3. animal epidemic colloidal-gold detecting-card according to claim 2, which is characterized in that the thermally conductive sheet be sheet metal,
Any one in graphite paper, graphene film.
4. animal epidemic colloidal-gold detecting-card according to claim 1 to 3, which is characterized in that the valve block packet
The push-and-pull portion for including valve block ontology and being fixedly linked with valve block ontology, push-and-pull portion upper end have be used to valve block apply thrust with
The pushing tow face for moving down valve block.
5. animal epidemic colloidal-gold detecting-card according to claim 1 to 3, which is characterized in that the valve block packet
The push-and-pull portion for including valve block ontology and being fixedly linked with valve block ontology, the push-and-pull portion are greater than the in the thickness of lateral tube axis direction
The distance between one shim and the second shim.
6. animal epidemic colloidal-gold detecting-card according to claim 5, which is characterized in that upper housing includes upper housing bottom plate
And it is fixed at the upper housing flange of upper housing bottom edge, the upper housing bottom plate is corresponding with the separator valve in transverse pipe
Position be provided with handle hole, the push-and-pull portion is inserted into the handle hole.
7. animal epidemic colloidal-gold detecting-card according to claim 6, which is characterized in that transversely manage in the push-and-pull portion
It is arranged on two sides of axis direction fluted.
8. animal epidemic colloidal-gold detecting-card according to claim 6, which is characterized in that the push-and-pull portion is perpendicular to upper
Height on Housing Base direction is not more than the thickness of upper housing bottom plate.
9. animal epidemic colloidal-gold detecting-card according to claim 1 to 3, which is characterized in that on the valve block
It is provided with positioning protrusion/positioning groove, is provided with positioning groove/positioning protrusion on the first shim and/or the second shim, it is fixed
Position protrusion is with positioning groove cooperation to limit valve block perpendicular to the movement on lateral tube axis direction.
10. animal epidemic colloidal-gold detecting-card according to claim 9, which is characterized in that first shim and/or
Positioning groove/the positioning protrusion being arranged on second shim is two groups, and interval setting, each group of positioning are recessed along the vertical direction
Slot/positioning protrusion quantity is equal with the positioning protrusion on valve block/positioning groove quantity；Positioning protrusion on the valve block/fixed
When position groove engages with one group in two groups of positioning groove/positioning protrusion on the first shim and/or the second shim, separate
Valve is in closed state, and when engaging with another group, separator valve is in the open state.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910845832.6A CN110531068B (en) | 2019-09-09 | 2019-09-09 | Animal epidemic disease colloidal gold detection card |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910845832.6A CN110531068B (en) | 2019-09-09 | 2019-09-09 | Animal epidemic disease colloidal gold detection card |
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| CN110531068A true CN110531068A (en) | 2019-12-03 |
| CN110531068B CN110531068B (en) | 2022-06-10 |
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| CN201910845832.6A Active CN110531068B (en) | 2019-09-09 | 2019-09-09 | Animal epidemic disease colloidal gold detection card |
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| CN205720238U (en) * | 2016-06-01 | 2016-11-23 | 黄志伟 | The quick multi-joint detection card of a kind of auxiliary heating |
| WO2017186063A1 (en) * | 2016-01-22 | 2017-11-02 | 上海快灵生物科技有限公司 | Centrifugal multi-channel microfluidic chip |
| CN207752019U (en) * | 2018-02-09 | 2018-08-21 | 黑龙江省林业科学研究所 | Strawberry crinkle virus immune colloid gold test paper detection device |
| WO2019057621A1 (en) * | 2017-09-20 | 2019-03-28 | Hamilton Medical Ag | Gas flow sensor for an artificial respiration device with reduced susceptibility to failure from humidity in the sensor housing |
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| WO2008071342A1 (en) * | 2006-12-11 | 2008-06-19 | The Jordanian Pharmaceutical Manufacturing Co. | Rapid immunochromatographic detection by amplification of the colloidal gold signal |
| CN202196067U (en) * | 2011-08-05 | 2012-04-18 | 浙江省农业科学院 | Embedded immune colloidal gold labeled rapid detection card |
| WO2015158818A1 (en) * | 2014-04-16 | 2015-10-22 | Amodia Bioservice Gmbh | Microfluidics module and cartridge for immunological and molecular diagnosis in an analysis machine |
| WO2017186063A1 (en) * | 2016-01-22 | 2017-11-02 | 上海快灵生物科技有限公司 | Centrifugal multi-channel microfluidic chip |
| CN205720238U (en) * | 2016-06-01 | 2016-11-23 | 黄志伟 | The quick multi-joint detection card of a kind of auxiliary heating |
| WO2019057621A1 (en) * | 2017-09-20 | 2019-03-28 | Hamilton Medical Ag | Gas flow sensor for an artificial respiration device with reduced susceptibility to failure from humidity in the sensor housing |
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|---|---|
| CN110531068B (en) | 2022-06-10 |
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