CN110477941B - Method, apparatus, computer device and readable storage medium for correcting intake value - Google Patents

Method, apparatus, computer device and readable storage medium for correcting intake value Download PDF

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CN110477941B
CN110477941B CN201910762729.5A CN201910762729A CN110477941B CN 110477941 B CN110477941 B CN 110477941B CN 201910762729 A CN201910762729 A CN 201910762729A CN 110477941 B CN110477941 B CN 110477941B
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sample
characteristic
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ingestion
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CN110477941A (en
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邓子林
王超
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Shanghai United Imaging Healthcare Co Ltd
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Abstract

The application relates to a correction method, a correction device, a computer device and a readable storage medium for an ingestion value, wherein a measurement characteristic parameter of a tester, the measurement ingestion value and a standard characteristic parameter corresponding to the age of the tester are obtained; calculating to obtain a characteristic parameter difference value according to the measured characteristic parameter and the standard characteristic parameter; according to the characteristic parameter difference and the change relation between the characteristic parameter difference and the ingestion value difference, the measured ingestion value is corrected to obtain a final ingestion value, the influence of characteristic parameter changes such as weight, body fat rate and the like on the ingestion value can be corrected, and the accuracy and consistency of the ingestion value of the same sample under different characteristic parameter conditions are ensured, so that a more accurate ingestion value can be obtained.

Description

Method, apparatus, computer device and readable storage medium for correcting intake value
Technical Field
The present invention relates to the field of medical diagnosis technology, and in particular, to a method, an apparatus, a computer device, and a readable storage medium for correcting an ingestion value.
Background
The PETCT imaging system can observe biological characteristics such as biochemical metabolism of tissues from molecular level in a noninvasive, dynamic and quantitative manner, and clinically, standard uptake values (standard uptake value, SUV) are often used as a judging standard of lesions. In the treatment monitoring of the later lesions and the pre-research of tumor drugs, the magnitude and accuracy of SUV values are directly closely related to the treatment effect of the lesions and the curative effect of the drugs, so that the accuracy of SUV values in a PETCT system is extremely important.
Currently, tahari et al in Optimum lean body formulation for correction of standardized uptake value in PET imaging found that the liver SUV of a patient sample correlated closely with the patient's weight. In chemotherapy and treatment of tumor patients, the body weight, body fat ratio, blood sugar and the like of a sample are generally changed, so that the monitoring of SUV accuracy is affected.
Disclosure of Invention
The application provides a correction method, a correction device, computer equipment and a readable storage medium for an ingestion value, which can correct the influence of characteristic parameter changes such as weight, body fat rate and the like on the ingestion value and ensure the accuracy and consistency of the ingestion value of the same sample under different characteristic parameter conditions.
A method of correcting an uptake value, the method comprising:
acquiring measurement characteristic parameters, measurement ingestion values and standard characteristic parameters corresponding to the age of the detector;
calculating to obtain a characteristic parameter difference value according to the measured characteristic parameter and the standard characteristic parameter;
and correcting the measured ingestion value according to the characteristic parameter difference value and the change relation between the characteristic parameter difference value and the ingestion value difference value to obtain a final ingestion value.
In an embodiment, before the correcting the measured intake value according to the characteristic parameter difference and the variation relationship between the characteristic parameter difference and the intake value difference, the method further includes:
acquiring a sample characteristic parameter and a sample uptake value corresponding to the sample characteristic parameter, and establishing a mapping relation between the sample uptake value and the sample characteristic parameter;
screening the mapping relation between the standard characteristic parameters and the reference ingestion values corresponding to the standard characteristic parameters from the mapping relation, and establishing a mapping table;
and calculating the change relation between the characteristic parameter difference value and the ingestion value difference value according to the mapping table.
In an embodiment, the step of screening the mapping relationship between the standard feature parameter and the reference ingestion value corresponding to the standard feature parameter, and the step of creating the mapping table includes: the characteristic parameters comprise at least two characteristic quantities;
taking any one of the characteristic parameters as a first characteristic quantity and the rest characteristic quantities as a second characteristic quantity;
selecting a plurality of samples which are the same as the second characteristic quantity from the mapping relation, and acquiring a plurality of first characteristic quantities of the samples and a plurality of corresponding sample uptake values;
and establishing a mapping table according to the plurality of first characteristic quantities and the plurality of sample ingestion values.
In an embodiment, the calculating the change relation between the feature parameter difference and the ingestion value difference according to the mapping table includes:
and calculating the change relation between the characteristic parameter difference value and the ingestion value difference value according to the mapping relation between the plurality of first characteristic quantities and the plurality of sample ingestion values in the mapping table.
In an embodiment, the obtaining the sample feature parameter and the sample uptake value corresponding to the sample feature parameter, and establishing the mapping relationship between the sample uptake value and the sample feature parameter includes: the sample characteristic parameters comprise sample morphological characteristic parameters and sample physiological characteristic parameters;
obtaining morphological characteristic parameters of a sample to be detected;
acquiring a sample uptake value and a scanning image of a sample to be detected, and acquiring physiological characteristic parameters of the sample according to the scanning image;
and establishing a mapping relation between the sample uptake value and the sample characteristic parameter according to the morphological characteristic parameter, the physiological characteristic parameter and the sample uptake value.
In an embodiment, the acquiring physiological characteristic parameters of the sample from the scanned image includes:
performing tissue segmentation on the scanned image to obtain tissue images of different tissues;
obtaining the percentage of each tissue according to the tissue image and the scanning image;
and obtaining physiological characteristic parameters of the sample according to the percentages.
In an embodiment, the correcting the measured ingestion value according to the characteristic parameter difference and the variation relationship between the characteristic parameter difference and the ingestion value difference, to obtain a final ingestion value includes:
acquiring an ingestion value difference value according to the characteristic parameter difference value and the change relation;
correcting the measured intake value according to the intake value difference value to eliminate the influence of the measured characteristic parameter on the measured intake value, and obtaining a final intake value.
A correction device for a standard uptake value, the device comprising:
the acquisition module is used for acquiring the measurement characteristic parameters, the measurement ingestion values and the standard characteristic parameters corresponding to the age of the detector;
the calculation module is used for calculating to obtain a characteristic parameter difference value according to the measured characteristic parameter and the standard characteristic parameter;
and the correction module is used for correcting the measured ingestion value according to the characteristic parameter difference value and the change relation between the characteristic parameter difference value and the ingestion value difference value to obtain a final ingestion value.
A computer device comprising a memory storing a computer program and a processor implementing the steps of the method described above when the processor executes the computer program.
A computer readable storage medium having stored thereon a computer program which when executed by a processor performs the steps of the above method.
The method, the device, the computer equipment and the readable storage medium for correcting the ingestion value are provided by the embodiment of the application, and the measurement characteristic parameters of the inspector, the measurement ingestion value and the standard characteristic parameters corresponding to the age of the inspector are obtained; calculating to obtain a characteristic parameter difference value according to the measured characteristic parameter and the standard characteristic parameter; and correcting the measured intake value according to the characteristic parameter difference value and the change relation between the characteristic parameter difference value and the intake value difference value to obtain a final intake value, correcting the influence of characteristic parameter changes such as weight, body fat rate and the like on the intake value, and ensuring the accuracy and consistency of the intake value of the same sample under different characteristic parameter conditions, thereby obtaining a more accurate intake value.
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In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described below, it being obvious that the drawings in the following description are only some embodiments of the present application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a flowchart of a method for calibrating an uptake value according to an embodiment;
FIG. 2 is a flowchart illustrating a variation relationship between the difference between the acquired feature parameter and the difference between the ingestion values according to one embodiment;
FIG. 3 is a block diagram showing a configuration of a correction device for an uptake value in one embodiment;
fig. 4 is an internal structural diagram of a computer device in one embodiment.
Detailed Description
In order to facilitate understanding of the present application, the following detailed description of the specific embodiments of the present application will be described in connection with the accompanying drawings, so that the foregoing objects, features, and advantages of the present application will be more readily understood. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application, the preferred embodiments of which are shown in the accompanying drawings. This application may, however, be embodied in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete. This application is intended to be limited to the details of the particular embodiments disclosed herein since it is to be understood that modifications may be made by those skilled in the art without departing from the spirit of the present application.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In the description of the present application, the meaning of "plurality" is at least two, such as two, three, etc., unless explicitly defined otherwise. In the description of the present application, the meaning of "several" means at least one, such as one, two, etc., unless explicitly defined otherwise.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
Positron emission computed tomography (PET) is a relatively advanced clinical examination imaging technique in the field of nuclear medicine. Is to mix a substance, which is generally necessary for the metabolism of living things, such as: glucose, protein, nucleic acid, fatty acid, short-lived radionuclides (e.g., 18F,11C, etc.) are labeled, and after injection into the human body, the radionuclides release positrons during decay, one positron encounters an electron after travelling a few tenths of a millimeter to a few millimeters and annihilates, thereby generating a pair of photons with energy of 511KeV in opposite directions. This pair of photons is captured by a highly sensitive camera and corrected for scatter and random information by a computer. By carrying out the same analysis processing on different positrons, we can obtain a three-dimensional image of the aggregation situation in the organism, thereby achieving the purpose of diagnosis.
A computed tomography apparatus (CT) generally comprises a gantry, a scan table and a console for operation by a physician. One side of the frame is provided with a bulb, and one side opposite to the bulb is provided with a detector. The console is a computer device for controlling scanning, and the computer device is also used for receiving the scanning data acquired by the detector, processing and reconstructing the data, and finally forming a CT image. When the CT is used for scanning, a patient lies on the scanning bed, the scanning bed sends the patient into the aperture of the frame, the bulb tube arranged on the frame emits X rays, the X rays penetrate through the patient and are received by the detector to form scanning data, the scanning data are transmitted to the computer equipment, and the computer equipment performs preliminary processing and image reconstruction on the scanning data to obtain CT images.
Fig. 1 is a flowchart of a method for correcting an intake value according to an embodiment, as shown in fig. 1, the method for correcting an intake value includes steps 110 to 130, in which:
step 110, obtaining the measured characteristic parameter, the measured intake value and the standard characteristic parameter corresponding to the age of the tester.
In the process of liver tumor detection or treatment of a detector, whether the liver of the detector is normal or not needs to be judged by taking the SUV value of the detector as a basis. The standard SUV value used for treatment monitoring and tumor judgment is a fixed value, when the SUV value measured by the detector is larger than the standard SUV value, the liver of the detector is judged to be diseased, and when the SUV value measured by the detector is smaller than or equal to the standard SUV value, the liver of the detector is judged to be normal.
Since the characteristic parameters of the examiner affect the measured uptake value thereof, it is necessary to acquire the measured characteristic parameters and the measured uptake value of the examiner. The measurement characteristic parameters include height, weight, liver size, blood sugar level, body fat ratio, etc. And then obtaining standard characteristic parameters corresponding to the age according to the age of the detector, wherein the standard characteristic parameters can be obtained through big data statistics. In an embodiment, the age bracket of the tester can be obtained according to the age of the tester, and then the standard characteristic parameters corresponding to the age bracket can be obtained according to the age bracket, and the gender of the tester is also taken into consideration. For example, a female inspector of 15 to 20 years old has a standard height of 150 cm, and a female inspector of 20 to 25 years old has a standard height of 160 cm. Each detector corresponds to a measurement uptake value, and if all measurement characteristic parameters of the detector are equal to or fall within the range of the standard characteristic parameters, the measurement SUV value of the detector is not affected by the measurement characteristic parameters and can be directly used as the basis for judging the pathological changes. If any measured characteristic parameter of the detector is not equal to the standard characteristic parameter or does not fall into the range of the standard characteristic parameter, the measured SUV value of the detector is affected by the measured characteristic parameter, and the measured uptake value is directly used as the basis for judging the pathological change after correction.
Step 120, calculating to obtain a characteristic parameter difference according to the measured characteristic parameter and the standard characteristic parameter.
The measured characteristic parameters of the inspector may not conform to the standard characteristic parameters, or may not conform to the corresponding standard characteristic parameters. If the detected person has a measurement characteristic parameter which does not accord with the standard characteristic parameter, calculating the difference value between the measurement characteristic parameter and the corresponding standard characteristic parameter to obtain a characteristic parameter difference value. For example, if the weight of the subject does not meet the standard, the difference between the actual weight of the subject and the standard weight corresponding to the age of the subject may be calculated. If the weight, body fat ratio and blood sugar of the detected person do not meet the standards, the difference value between the measurement characteristic parameter and the standard characteristic parameter needs to be correspondingly obtained.
And 130, correcting the measured ingestion value according to the characteristic parameter difference value and the change relation between the characteristic parameter difference value and the ingestion value difference value to obtain a final ingestion value.
The change relation between the feature parameter difference and the ingestion value difference may be stored in advance, for example, may be stored in a form of a table, a data pair or a graph, and the specific storage mode is not limited in this embodiment. During detection, the measured uptake value is corrected by directly searching the change relation between the characteristic parameter difference and the uptake value difference according to the characteristic parameter difference, and a final uptake value is obtained. Specifically, since the influence degree of each characteristic parameter on the ingestion value is different, after the characteristic parameter difference is obtained, the change relation between the corresponding characteristic parameter difference and the ingestion value difference needs to be searched. For example, if the weight of the tester does not meet the standard, after calculating the difference between the weight of the tester and the standard weight, the change relation between the weight difference and the intake value difference is searched correspondingly, and the measured intake value is corrected according to the change relation, so as to obtain the final intake value.
In an embodiment, correcting the measured uptake value according to the characteristic parameter difference and the variation relationship between the characteristic parameter difference and the uptake value difference, to obtain a final uptake value includes:
acquiring an ingestion value difference value according to the characteristic parameter difference value and the change relation;
correcting the measured uptake value according to the uptake value difference value to eliminate the influence of the measured characteristic parameter on the measured uptake value, and obtaining a final uptake value.
Specifically, after the difference between the characteristic parameter of the tester and the standard characteristic parameter is obtained, the difference of the uptake value is obtained according to the change relation between the characteristic parameter and the difference of the uptake value, namely the influence value of the characteristic parameter on the uptake value of the tester. For example, if the difference of the characteristic parameters is larger, the difference of the intake values is larger, which means that the intake value will increase with the increase of the characteristic parameters, so that the influence value of the characteristic parameters on the measured intake value can be subtracted on the basis of the measured intake value, that is, the influence of the measured characteristic parameters on the measured intake value can be eliminated, and the final intake value is obtained.
According to the method for correcting the uptake value, the measured characteristic parameters of the testers, the measured uptake value and the standard characteristic parameters corresponding to the ages of the testers are obtained; calculating to obtain a characteristic parameter difference value according to the measured characteristic parameter and the standard characteristic parameter; according to the characteristic parameter difference and the change relation between the characteristic parameter difference and the ingestion value difference, the measured ingestion value is corrected to obtain a final ingestion value, the influence of characteristic parameter changes such as weight, body fat rate and the like on the ingestion value can be corrected, and the accuracy and consistency of the ingestion value of the same sample under different characteristic parameter conditions are ensured, so that a more accurate ingestion value can be obtained.
In an embodiment, as shown in fig. 2, before correcting the measured intake value according to the characteristic parameter difference and the variation relationship between the characteristic parameter difference and the intake value difference, the intake value correction method further includes steps 210 to 230, wherein:
step 210, obtaining a sample feature parameter and a sample uptake value corresponding to the sample feature parameter, and establishing a mapping relationship between the sample uptake value and the sample feature parameter.
Before the detection of the detector, the influence of different characteristic parameters on the intake value needs to be counted, namely, the change relation of the characteristic parameter difference value and the intake value difference value, for example, the change relation of the body fat ratio change amount and the intake value, is counted, and the measured intake value is corrected according to the change relation. The variation relation between the difference of the characteristic parameters and the difference of the ingestion values is firstly required to collect clinical scanning data of a large number of samples, such as clinical scanning data of twenty-four thousands of cases, wherein the samples comprise samples of different heights, different weights, different body fat rates, different liver sizes and the like. According to the statistical sample data, a mapping relation between the uptake value of each sample and the characteristic parameters of the sample is established, for example, the mapping relation of each sample can be as follows:
TABLE 1
Age of Height of body Weight of body Liver size Blood glucose level Ratio of body fat Intake value
And 220, screening the mapping relation between the standard characteristic parameters and the reference ingestion values corresponding to the standard characteristic parameters from the mapping relation, and establishing a mapping table.
In an embodiment, the feature parameter comprises at least two feature quantities. As shown in table 1, the characteristic parameters of each sample include height, weight, liver size, blood glucose level, body fat ratio, and a plurality of characteristic amounts. Screening the mapping relation between the standard characteristic parameters and the reference ingestion values corresponding to the standard characteristic parameters from the mapping relation, and establishing a mapping table comprises the following steps:
any one of the feature parameters is used as a first feature, and the rest of the feature parameters are used as second feature.
And selecting a plurality of samples which are the same as the second characteristic quantity from the mapping relation, and acquiring a plurality of first characteristic quantities and a plurality of corresponding sample ingestion values of the plurality of samples.
And establishing a mapping table according to the plurality of first characteristic quantities and the plurality of sample ingestion values.
Specifically, first, any one feature quantity is selected from the mapping relation of any one sample as a first feature quantity, and an ingestion value corresponding to the sample is correspondingly acquired. In the sample map, other feature amounts than the first feature amount are regarded as second feature amounts. And then selecting a plurality of samples with the same numerical value as the second characteristic quantity in the mapping relation of other samples, and acquiring ingestion values respectively corresponding to the plurality of samples. And establishing a mapping table of the first characteristic quantity and the ingestion value according to the first characteristic quantity and the ingestion value of the selected multiple samples.
For example, body fat ratio is used as a first characteristic amount, and body weight, age, height, liver size, and blood glucose level are used as a second characteristic amount. And then selecting samples with the same second characteristic quantity from the mapping relation of all samples so as to ensure that other characteristic parameters of each selected sample are the same except for the body fat ratio. And constructing a mapping table of the solid fat ratio and the uptake value according to the body fat ratio and the uptake value of the plurality of selected samples.
In an embodiment, a sample with standard characteristic parameters may be selected as the first sample, one of the characteristic parameters is selected as the first characteristic parameter in the mapping table of the first sample, the other characteristic parameters are selected as the second characteristic parameters, and the ingestion value corresponding to the first sample is selected as the reference ingestion value. And then selecting a plurality of samples with the same numerical value as the second characteristic quantity in the mapping relation of other samples, and acquiring ingestion values respectively corresponding to the plurality of samples. And establishing a mapping table of the first characteristic quantity and the ingestion value according to the first characteristic quantity and the ingestion value of the selected multiple samples.
Step 230, calculating the variation relationship between the characteristic parameter difference and the ingestion value difference according to the mapping table.
In an embodiment, calculating the variation relationship between the feature parameter difference and the ingestion value difference according to the mapping table includes:
and calculating the change relation between the characteristic parameter difference value and the ingestion value difference value according to the mapping relation between the plurality of first characteristic quantities and the plurality of sample ingestion values in the mapping table.
Specifically, the difference values of the plurality of first characteristic quantities and the corresponding ingestion values are calculated, and the change relation between the characteristic parameter difference values and the ingestion value difference values is obtained according to the plurality of first characteristic quantity difference values and the corresponding plurality of ingestion value difference values.
In an embodiment, obtaining the sample feature parameter and a sample uptake value corresponding to the sample feature parameter, and establishing a mapping relationship between the sample uptake value and the sample feature parameter includes: the sample characteristic parameters comprise sample morphological characteristic parameters and sample physiological characteristic parameters;
and obtaining morphological characteristic parameters of the sample to be detected. The morphological characteristic parameters comprise parameters such as age, height, weight and the like of a sample to be detected.
And acquiring a sample uptake value and a scanning image of the sample to be detected, and acquiring physiological characteristic parameters of the sample according to the scanning image.
The scanning image can be obtained by adopting a PET/CT system with a uniform model, so that the measurement error caused by system difference can be reduced, and the measurement consistency is improved.
In one embodiment, acquiring physiological characteristic parameters of a sample from a scanned image includes:
carrying out tissue segmentation on the scanned image to obtain tissue images of different tissues; obtaining the percentage of each tissue according to the tissue image and the scanning image; and obtaining physiological characteristic parameters of the sample according to the percentages.
The physiological characteristic parameters mainly comprise liver size, blood glucose level, body fat ratio and other parameters of the sample. The total content of fat, muscle and soft tissues in the sample can be obtained according to the whole scanned image of the sample, the specific content of each tissue can be obtained according to the segmented tissue image, then the percentage of the total content of each tissue can be obtained by combining the tissue image and the scanned image, and the physiological characteristic parameters of the sample can be obtained according to the percentage.
And establishing a mapping relation between the sample uptake value and the sample characteristic parameter according to the morphological characteristic parameter, the physiological characteristic parameter and the sample uptake value.
It should be understood that, although the steps in the flowcharts of fig. 1 and 2 are shown in order as indicated by the arrows, these steps are not necessarily performed in order as indicated by the arrows. The steps are not strictly limited to the order of execution unless explicitly recited herein, and the steps may be executed in other orders. Moreover, at least some of the steps in fig. 1 and 2 may include multiple sub-steps or stages that are not necessarily performed at the same time, but may be performed at different times, nor does the order in which the sub-steps or stages are performed necessarily occur in sequence, but may be performed alternately or alternately with at least a portion of the other steps or sub-steps of other steps.
In one embodiment, as shown in fig. 3, there is provided an ingestion value correction apparatus including: an acquisition module 310, a calculation module 320, and a correction module 330, wherein:
an obtaining module 310, configured to obtain a measurement feature parameter, a measurement ingestion value, and a standard feature parameter corresponding to an age of a tester;
the calculating module 320 is configured to calculate a feature parameter difference value according to the measured feature parameter and the standard feature parameter;
the correction module 330 is configured to correct the measured ingestion value according to the characteristic parameter difference and a variation relationship between the characteristic parameter difference and the ingestion value difference, so as to obtain a final ingestion value.
In an embodiment, the uptake value correction device further includes a statistics module, configured to obtain a sample feature parameter and a sample uptake value corresponding to the sample feature parameter before correcting the measured uptake value according to the feature parameter difference and a variation relationship between the feature parameter difference and the uptake value difference, and establish a mapping relationship between the sample uptake value and the sample feature parameter;
screening the mapping relation between the standard characteristic parameters and the reference ingestion values corresponding to the standard characteristic parameters from the mapping relation, and establishing a mapping table;
and calculating the change relation between the characteristic parameter difference value and the ingestion value difference value according to the mapping table.
In an embodiment, the statistics module screens the mapping relation between the standard feature parameter and the reference ingestion value corresponding to the standard feature parameter from the mapping relation, and the creating the mapping table includes: the characteristic parameter includes at least two characteristic quantities;
taking any one of the characteristic parameters as a first characteristic quantity and the rest characteristic quantities as a second characteristic quantity;
selecting a plurality of samples which are the same as the second characteristic quantity from the mapping relation, and acquiring a plurality of first characteristic quantities and a plurality of corresponding sample uptake values of the plurality of samples;
and establishing a mapping table according to the plurality of first characteristic quantities and the plurality of sample ingestion values.
In an embodiment, the calculating, by the statistics module, a variation relationship between the feature parameter difference and the ingestion value difference according to the mapping table includes:
and calculating the change relation between the characteristic parameter difference value and the ingestion value difference value according to the mapping relation between the plurality of first characteristic quantities and the plurality of sample ingestion values in the mapping table.
In an embodiment, the statistical module obtains a sample feature parameter and a sample uptake value corresponding to the sample feature parameter, and establishing a mapping relationship between the sample uptake value and the sample feature parameter includes: the sample characteristic parameters comprise sample morphological characteristic parameters and sample physiological characteristic parameters;
obtaining morphological characteristic parameters of a sample to be detected;
acquiring a sample uptake value and a scanning image of a sample to be detected, and acquiring physiological characteristic parameters of the sample according to the scanning image;
and establishing a mapping relation between the sample uptake value and the sample characteristic parameter according to the morphological characteristic parameter, the physiological characteristic parameter and the sample uptake value.
In one embodiment, the statistical module obtains physiological characteristic parameters of the sample according to the scanned image, including:
carrying out tissue segmentation on the scanned image to obtain tissue images of different tissues;
obtaining the percentage of each tissue according to the tissue image and the scanning image;
and obtaining physiological characteristic parameters of the sample according to the percentages.
In an embodiment, the statistics module corrects the measured uptake value according to the characteristic parameter difference and a variation relationship between the characteristic parameter difference and the uptake value difference, and the obtaining the final uptake value includes:
acquiring an ingestion value difference value according to the characteristic parameter difference value and the change relation;
correcting the measured uptake value according to the uptake value difference value to eliminate the influence of the measured characteristic parameter on the measured uptake value, and obtaining a final uptake value.
For specific limitations of the ingestion value correction apparatus, reference may be made to the above limitations of the ingestion value correction method, and no further description is given here. The respective modules in the above-described ingestion value correction apparatus may be implemented in whole or in part by software, hardware, or a combination thereof. The above modules may be embedded in hardware or may be independent of a processor in the computer device, or may be stored in software in a memory in the computer device, so that the processor may call and execute operations corresponding to the above modules.
In one embodiment, a computer device is provided, which may be a terminal, and the internal structure of which may be as shown in fig. 4. The computer device includes a processor, a memory, a network interface, a display screen, and an input device connected by a system bus. Wherein the processor of the computer device is configured to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for the operation of the operating system and computer programs in the non-volatile storage media. The network interface of the computer device is used for communicating with an external terminal through a network connection. The computer program is executed by a processor to implement a method of ingest value correction. The display screen of the computer equipment can be a liquid crystal display screen or an electronic ink display screen, and the input device of the computer equipment can be a touch layer covered on the display screen, can also be keys, a track ball or a touch pad arranged on the shell of the computer equipment, and can also be an external keyboard, a touch pad or a mouse and the like.
Those skilled in the art will appreciate that the structures shown in FIG. 4 are block diagrams only and do not constitute a limitation of the computer device on which the present aspects apply, and that a particular computer device may include more or less components than those shown, or may combine some of the components, or have a different arrangement of components.
In one embodiment, a computer device is provided comprising a memory and a processor, the memory having stored therein a computer program, the processor when executing the computer program performing the steps of:
acquiring measurement characteristic parameters, measurement ingestion values and standard characteristic parameters corresponding to the age of the detector;
calculating to obtain a characteristic parameter difference value according to the measured characteristic parameter and the standard characteristic parameter;
and correcting the measured ingestion value according to the characteristic parameter difference value and the change relation between the characteristic parameter difference value and the ingestion value difference value to obtain a final ingestion value.
In one embodiment, the processor when executing the computer program further performs the steps of:
acquiring a sample characteristic parameter and a sample uptake value corresponding to the sample characteristic parameter, and establishing a mapping relation between the sample uptake value and the sample characteristic parameter;
screening the mapping relation between the standard characteristic parameters and the reference ingestion values corresponding to the standard characteristic parameters from the mapping relation, and establishing a mapping table;
and calculating the change relation between the characteristic parameter difference value and the ingestion value difference value according to the mapping table.
In one embodiment, the processor when executing the computer program further performs the steps of: the characteristic parameters comprise at least two characteristic quantities;
taking any one of the characteristic parameters as a first characteristic quantity and the rest characteristic quantities as a second characteristic quantity;
selecting a plurality of samples which are the same as the second characteristic quantity from the mapping relation, and acquiring a plurality of first characteristic quantities of the samples and a plurality of corresponding sample uptake values;
and establishing a mapping table according to the plurality of first characteristic quantities and the plurality of sample ingestion values.
In one embodiment, the processor when executing the computer program further performs the steps of:
and calculating the change relation between the characteristic parameter difference value and the ingestion value difference value according to the mapping relation between the plurality of first characteristic quantities and the plurality of sample ingestion values in the mapping table.
In one embodiment, the processor when executing the computer program further performs the steps of: the sample characteristic parameters comprise sample morphological characteristic parameters and sample physiological characteristic parameters;
obtaining morphological characteristic parameters of a sample to be detected;
acquiring a sample uptake value and a scanning image of a sample to be detected, and acquiring physiological characteristic parameters of the sample according to the scanning image;
and establishing a mapping relation between the sample uptake value and the sample characteristic parameter according to the morphological characteristic parameter, the physiological characteristic parameter and the sample uptake value.
In one embodiment, the processor when executing the computer program further performs the steps of:
performing tissue segmentation on the scanned image to obtain tissue images of different tissues;
obtaining the percentage of each tissue according to the tissue image and the scanning image;
and obtaining physiological characteristic parameters of the sample according to the percentages.
In one embodiment, the processor when executing the computer program further performs the steps of:
acquiring an ingestion value difference value according to the characteristic parameter difference value and the change relation;
correcting the measured intake value according to the intake value difference value to eliminate the influence of the measured characteristic parameter on the measured intake value, and obtaining a final intake value.
In one embodiment, a computer readable storage medium is provided having a computer program stored thereon, which when executed by a processor, performs the steps of:
acquiring measurement characteristic parameters, measurement ingestion values and standard characteristic parameters corresponding to the age of the detector;
calculating to obtain a characteristic parameter difference value according to the measured characteristic parameter and the standard characteristic parameter;
and correcting the measured ingestion value according to the characteristic parameter difference value and the change relation between the characteristic parameter difference value and the ingestion value difference value to obtain a final ingestion value.
In one embodiment, the processor when executing the computer program further performs the steps of:
acquiring a sample characteristic parameter and a sample uptake value corresponding to the sample characteristic parameter, and establishing a mapping relation between the sample uptake value and the sample characteristic parameter;
screening the mapping relation between the standard characteristic parameters and the reference ingestion values corresponding to the standard characteristic parameters from the mapping relation, and establishing a mapping table;
and calculating the change relation between the characteristic parameter difference value and the ingestion value difference value according to the mapping table.
In one embodiment, the processor when executing the computer program further performs the steps of: the characteristic parameters comprise at least two characteristic quantities;
taking any one of the characteristic parameters as a first characteristic quantity and the rest characteristic quantities as a second characteristic quantity;
selecting a plurality of samples which are the same as the second characteristic quantity from the mapping relation, and acquiring a plurality of first characteristic quantities of the samples and a plurality of corresponding sample uptake values;
and establishing a mapping table according to the plurality of first characteristic quantities and the plurality of sample ingestion values.
In one embodiment, the processor when executing the computer program further performs the steps of:
and calculating the change relation between the characteristic parameter difference value and the ingestion value difference value according to the mapping relation between the plurality of first characteristic quantities and the plurality of sample ingestion values in the mapping table.
In one embodiment, the processor when executing the computer program further performs the steps of: the sample characteristic parameters comprise sample morphological characteristic parameters and sample physiological characteristic parameters;
obtaining morphological characteristic parameters of a sample to be detected;
acquiring a sample uptake value and a scanning image of a sample to be detected, and acquiring physiological characteristic parameters of the sample according to the scanning image;
and establishing a mapping relation between the sample uptake value and the sample characteristic parameter according to the morphological characteristic parameter, the physiological characteristic parameter and the sample uptake value.
In one embodiment, the processor when executing the computer program further performs the steps of:
performing tissue segmentation on the scanned image to obtain tissue images of different tissues;
obtaining the percentage of each tissue according to the tissue image and the scanning image;
and obtaining physiological characteristic parameters of the sample according to the percentages.
In one embodiment, the processor when executing the computer program further performs the steps of:
acquiring an ingestion value difference value according to the characteristic parameter difference value and the change relation;
correcting the measured intake value according to the intake value difference value to eliminate the influence of the measured characteristic parameter on the measured intake value, and obtaining a final intake value.
Those skilled in the art will appreciate that implementing all or part of the above described methods may be accomplished by way of a computer program stored on a non-transitory computer readable storage medium, which when executed, may comprise the steps of the embodiments of the methods described above. Any reference to memory, storage, database, or other medium used in the various embodiments provided herein may include non-volatile and/or volatile memory. The nonvolatile memory can include Read Only Memory (ROM), programmable ROM (PROM), electrically Programmable ROM (EPROM), electrically Erasable Programmable ROM (EEPROM), or flash memory. Volatile memory can include Random Access Memory (RAM) or external cache memory. By way of illustration and not limitation, RAM is available in a variety of forms such as Static RAM (SRAM), dynamic RAM (DRAM), synchronous DRAM (SDRAM), double Data Rate SDRAM (DDRSDRAM), enhanced SDRAM (ESDRAM), synchronous Link DRAM (SLDRAM), memory bus direct RAM (RDRAM), direct memory bus dynamic RAM (DRDRAM), and memory bus dynamic RAM (RDRAM), among others.
The technical features of the above-described embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above-described embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The above examples illustrate only a few embodiments of the invention, which are described in detail and are not to be construed as limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.

Claims (9)

1. A method of correcting an ingestion value, the method comprising:
acquiring measurement characteristic parameters, measurement ingestion values and standard characteristic parameters corresponding to the age of the detector;
calculating to obtain a characteristic parameter difference value according to the measured characteristic parameter and the standard characteristic parameter;
correcting the measured uptake value according to the characteristic parameter difference and the change relation between the characteristic parameter difference and the uptake value difference to obtain a final uptake value, wherein the method comprises the following steps: acquiring an ingestion value difference value according to the characteristic parameter difference value and the change relation; correcting the measured intake value according to the intake value difference value to eliminate the influence of the measured characteristic parameter on the measured intake value, and obtaining a final intake value.
2. The method of claim 1, wherein before correcting the measured intake value based on the characteristic parameter difference and the variation relationship between the characteristic parameter difference and the intake value difference, the method further comprises:
acquiring a sample characteristic parameter and a sample uptake value corresponding to the sample characteristic parameter, and establishing a mapping relation between the sample uptake value and the sample characteristic parameter;
screening the mapping relation between the standard characteristic parameters and the reference ingestion values corresponding to the standard characteristic parameters from the mapping relation, and establishing a mapping table;
and calculating the change relation between the characteristic parameter difference value and the ingestion value difference value according to the mapping table.
3. The method according to claim 2, wherein the step of screening the mapping relationship between the standard feature parameter and the reference ingestion value corresponding to the standard feature parameter, and the step of creating the mapping table includes: the characteristic parameters comprise at least two characteristic quantities;
taking any one of the characteristic parameters as a first characteristic quantity and the rest characteristic quantities as a second characteristic quantity;
selecting a plurality of samples which are the same as the second characteristic quantity from the mapping relation, and acquiring a plurality of first characteristic quantities of the samples and a plurality of corresponding sample uptake values;
and establishing a mapping table according to the plurality of first characteristic quantities and the plurality of sample ingestion values.
4. The method of claim 3, wherein calculating a variation relationship between the feature parameter difference and the ingestion value difference from the mapping table comprises:
and calculating the change relation between the characteristic parameter difference value and the ingestion value difference value according to the mapping relation between the plurality of first characteristic quantities and the plurality of sample ingestion values in the mapping table.
5. The method of claim 2, wherein the obtaining the sample feature parameter and the sample uptake value corresponding to the sample feature parameter, and establishing the mapping relationship between the sample uptake value and the sample feature parameter comprises: the sample characteristic parameters comprise sample morphological characteristic parameters and sample physiological characteristic parameters;
obtaining morphological characteristic parameters of a sample to be detected;
acquiring a sample uptake value and a scanning image of a sample to be detected, and acquiring physiological characteristic parameters of the sample according to the scanning image;
and establishing a mapping relation between the sample uptake value and the sample characteristic parameter according to the morphological characteristic parameter, the physiological characteristic parameter and the sample uptake value.
6. The method of claim 5, wherein the acquiring physiological characteristic parameters of the sample from the scanned image comprises:
performing tissue segmentation on the scanned image to obtain tissue images of different tissues;
obtaining the percentage of each tissue according to the tissue image and the scanning image;
and obtaining physiological characteristic parameters of the sample according to the percentages.
7. A correction device for a standard uptake value, the device comprising:
the acquisition module is used for acquiring the measurement characteristic parameters, the measurement ingestion values and the standard characteristic parameters corresponding to the age of the detector;
the calculation module is used for calculating to obtain a characteristic parameter difference value according to the measured characteristic parameter and the standard characteristic parameter;
the correction module is configured to correct the measured ingestion value according to the characteristic parameter difference and a variation relationship between the characteristic parameter difference and the ingestion value difference, to obtain a final ingestion value, and includes: acquiring an ingestion value difference value according to the characteristic parameter difference value and the change relation; correcting the measured intake value according to the intake value difference value to eliminate the influence of the measured characteristic parameter on the measured intake value, and obtaining a final intake value.
8. A computer device comprising a memory and a processor, the memory storing a computer program, characterized in that the processor implements the steps of the method of any of claims 1 to 6 when the computer program is executed.
9. A computer readable storage medium, on which a computer program is stored, characterized in that the computer program, when being executed by a processor, implements the steps of the method of any of claims 1 to 6.
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