CN110448320A - For the bulb tube component of CBCT system and the method for reconstructing of dual intensity three-dimensional volumetric images - Google Patents

For the bulb tube component of CBCT system and the method for reconstructing of dual intensity three-dimensional volumetric images Download PDF

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Publication number
CN110448320A
CN110448320A CN201910708583.6A CN201910708583A CN110448320A CN 110448320 A CN110448320 A CN 110448320A CN 201910708583 A CN201910708583 A CN 201910708583A CN 110448320 A CN110448320 A CN 110448320A
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China
Prior art keywords
ray
projected image
energy
low energy
filter unit
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CN201910708583.6A
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Chinese (zh)
Inventor
邱立忠
田新智
金铁
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New Mileage Medical Accelerator (wuxi) Co Ltd
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New Mileage Medical Accelerator (wuxi) Co Ltd
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Priority to CN201910708583.6A priority Critical patent/CN110448320A/en
Publication of CN110448320A publication Critical patent/CN110448320A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03Computerised tomographs
    • A61B6/032Transmission computed tomography [CT]
    • A61B6/035Mechanical aspects of CT
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/40Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for generating radiation specially adapted for radiation diagnosis
    • A61B6/4064Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for generating radiation specially adapted for radiation diagnosis specially adapted for producing a particular type of beam
    • A61B6/4085Cone-beams

Abstract

The application discloses a kind of bulb tube component for CBCT system, including the transmitting unit for emitting X-ray;The filter unit of first part and second part at least with different thickness, the filter unit can block the X-ray of the transmitting unit transmitting respectively with first part and second part, to generate the X-ray beam of different-energy.Use the CBCT system of the bulb tube component with an x-ray source, a detector realizes dual intensity CBCT system and device, and the system apparatus arrangements are simple, and cost is relatively low.Furthermore, disclosed herein as well is a kind of method for reconstructing of dual intensity three-dimensional volumetric images, this method not only applies high and low energy dampening information, and spatial match and correction for attenuation have been done for high and low energy attenuation data, it can more accurately include bone information and soft tissue information in the human body three-dimensional volume data of reconstruction.

Description

For the bulb tube component of CBCT system and the method for reconstructing of dual intensity three-dimensional volumetric images
Technical field
The present invention relates to dual intensity power spectrum conical beam CT (CBCT) system regions, in particular to a kind of bulbs for the system Component and the dual intensity power spectrum construction method for using the bulb tube component.
Background technique
According to the attenuation attributes of X-ray, a kind of X-ray of fixed energies is more sensitive to the decaying of specific density substance, and Less sensitive to the decaying of other dense matters, this is especially prominent in the attenuation measurement of human body different tissues, and density is high Bone tissue is sensitive to the X-ray attenuation of high energy, and the lower soft tissue of density is more sensitive to the decaying of low energy X ray.
Dual intensity power spectrum conical beam CT (CBCT) system is by high pressure generator, bulb (relating to ray for emitting X), detector group At.When work, with the x-ray bombardment target of different-energy, high energy and low energy data for projection, adjacent high and low energy projection are obtained Data carry out time-space registration, rebuild three-dimensional volumetric images.CBCT system uses high energy and low energy X ray simultaneously, can effectively receive The characteristic information for collecting different anatomic tissue morphology is conducive to distinguish the morphological features such as bone and soft tissue.
Existing CBCT system mainly obtains the X-ray of different-energy in two ways:
The first is to increase an x-ray source and a detector, so that synchronization has the X of two beam different-energies to penetrate Line irradiates target, and detector obtains high energy and low energy data for projection respectively.The shortcomings that this mode is to increase equipment cost and set Count complexity.
Second is during primary complete CBCT Mode scans using identical X-ray energy, and detector has Decaying material is added in the interlayer for special interlayer, to realize that single x-ray source obtains two kinds of attenuation projection data.This is System is easily achieved, and identical X-ray energy can effectively reduce light beam fluctuation and introduce additional noise.But this method While increasing equipment cost, it is also necessary to increasingly complex energy spectrum reconstruction process.
Summary of the invention
In view of the problems in the background art, the present invention provides a kind of bulb tube component for CBCT system, comprising:
For emitting the transmitting unit of X-ray;
The filter unit of first part and second part at least with different thickness, the filter unit can respectively with First part and second part block the X-ray of the transmitting unit transmitting, to generate the X-ray beam of different-energy.
In certain embodiments of the present invention, before the filter unit can rotatably be arranged in the transmitting unit Side, half have thickness L1, the other half is with thickness L2
In certain embodiments of the present invention, the transmitting unit is bulb, and the bulb is sent out with circular X-ray Perforation;The filter unit has filtering thin slice in a ring, and the width of the filtering thin slice is greater than or equal to the X of the bulb The diameter in ray emission hole.
In certain embodiments of the present invention, the filter unit includes: the rotation being set on the bulb shell Axis;And it is set to the carrying tablet in the rotary shaft, the carrying tablet has for the loop filtering thin slice annular to be arranged Hollow out.
In certain embodiments of the present invention, revolving speed w=(2 π × the FPS/2)/second of the filter unit, wherein FPS For Image Acquisition frame frequency.
Bulb tube component provided by the invention has specific thicknesses L in the setting of the front of X-ray emission unit1First part With thickness L2Second part filter unit, to obtain the X-ray of two kinds of different-energies, respectively to highdensity bone tissue and The soft tissue decaying of low-density is sensitive, to realize dual intensity CBCT system and device.The device and other CBCT system implementation devices It compares, it is only necessary to an x-ray source, a detector are achieved that dual intensity power spectrum CBCT system, and the structure of the device is simple, at This is lower, it is easy to accomplish.
In addition, the present invention also provides a kind of method for reconstructing of dual intensity three-dimensional volumetric images characterized by comprising
A. arrange that filter unit, the filter unit at least have different-thickness L in X-ray emission unit front end1And L2's First part and second part;
B. it is penetrated respectively with the X that the first part of different-thickness and second part alternately block the transmitting unit transmitting Line has high-energy E to generate1With low energy E2X-ray beam, and with the high-energy E1With low energy E2X-ray beam point It Zhao She not object to be measured;
C. the high energy projected image Pro_L for penetrating object to be measured is obtained1With low energy projected image Pro_L2, two width are projected Image carries out spatial registration, to the low energy projected image Pro_L2Carry out correction for attenuation;
D. the high energy projected image Pro_L is merged1With the low energy projected image Pro_L after correction for attenuation2, with Obtain fusion projected image;
E. according to the fusion backprojection image reconstruction dual intensity three-dimensional volumetric images.
In certain embodiments of the present invention, the step c includes:
By low energy projected image Pro_L2It is registrated to high energy projected image Pro_L1, it is assumed that joined by two images registration result Array at transformation matrix be T, then:
T(Pro_L2)→(Pro_L1);
Assuming that high energy projected image Pro_L1Corresponding effective rays energy is E1, effective linear attenuation coefficient is μ1, irradiation Sigmatron intensity before and after target and filter, dielectric is respectively I0And I1, low energy projected image Pro_L2Corresponding effective rays Energy is E2, effective linear attenuation coefficient is μ2, the low energy X ray intensity irradiated before and after target and filter, dielectric is respectively I0With I2, high energy projected image Pro_L1Pixel at middle any position (x, y) corresponds to X-ray across target with a thickness of t, then
I1(x, y)=I0(x,y)*exp(-μ1*(t+L1));
I2(x, y)=I0(x,y)*(exp(μ21)+I1(x,y)/I0(x,y)+(L1-L2)*μ2)。
In certain embodiments of the present invention, the step d includes:
According to I (x, y)=λ * I1(x,y)+(1-λ)*I2Pixel at any position (x, y) in (x, y) acquisition blending image Intensity value, wherein λ is weight coefficient, and 0 < λ < 1.
In certain embodiments of the present invention, the step e includes: to rebuild dual intensity three-D volumes figure using FDK algorithm Picture.
The method for reconstructing of dual intensity three-dimensional volumetric images provided by the invention not only applies high and low energy dampening information, but also right Spatial match and correction for attenuation have been done in high and low energy attenuation data, it can be in the human body three-dimensional volume data of reconstruction more accurately It include bone information and soft tissue information.
Detailed description of the invention
Fig. 1 is the bulb tube component decomposition diagram of an embodiment of the present invention;
Fig. 2 is the bulb tube component combination diagram of an embodiment of the present invention;
Fig. 3 is waveform diagram of the filter unit of an embodiment of the present invention under adjacent two frame;
Fig. 4 is the flow chart of the method for reconstructing of the dual intensity three-dimensional volumetric images of an embodiment of the present invention.
Specific embodiment
In order to keep the purposes, technical schemes and advantages of invention clearer, in the following with reference to the drawings and specific embodiments to hair It is bright to be described in further detail.Although showing disclosure exemplary embodiment in attached drawing, it being understood, however, that can be with each Kind form is realized the present invention and be should not be limited by the embodiments set forth herein.It is to be able on the contrary, providing these embodiments Thorough explanation of the being more convenient for present invention, and design of the invention can be communicated completely to those skilled in the art.
As shown in Figure 1, the bulb tube component that present embodiment provides includes transmitting unit 1 and the filter for emitting X-ray Wave unit 2.The filter unit 2 first part 21 at least with different thickness and second part 22, so that it can distinguish The X-ray of the transmitting of transmitting unit 1 is blocked with first part 21 and second part 22, and then is generated with high-energy E1And low energy E2X-ray beam.Filter unit 2 can rotatably be arranged in the front of transmitting unit 1, and half has thickness L1, the other half tool There is thickness L2
As shown in Fig. 2, further, which uses existing bulb, which sends out with circular X-ray Perforation 11, therefore the X-ray that bulb projects is pencil-beam, i.e., section is circle when X-ray projects bulb.Filter unit 2 is then adopted With the filtering thin slice of the aluminum of annular, annular width is greater than or equal to the diameter in the X-ray emission hole 11 of bulb.The annular The half (first part 21) for filtering thin slice has thickness L1, the other half (second part 22) has thickness L2
In the present embodiment, filter unit 2 further includes the rotary shaft 23 being set on bulb shell and is set to rotation Carrying tablet 24 on axis 23, the carrying tablet 24 have the annular hollow out for arranging the filtering thin slice of annular, so that annular Filtering thin slice can be set in the annular hollow out, and then the filtering thin slice of annular rotates under the drive of rotary shaft 23.Rotation Axis 23 is driven by motor (not shown).The loop filtering thin slice can be rotated during X-ray exposure with fast and stable as a result, X-ray wave beam is set successively to generate high-energy E by the first part of different-thickness 21 and the modulation of second part 221With low energy E2X Beam irradiates target.
Referring to shown in Fig. 3, if Image Acquisition frame frequency FPS=10, every frame image exposure pulsewidth 20ms, interpret blueprints pulsewidth 80ms, 2 revolving speed w=π/0.1s=10 π=5*2 π of filter unit/second, i.e. 2 each second of filter unit turns 5 turns just same with exposure cycle It walks, then revolving speed w=(2 π * the FPS/2)/second of filter unit 2.
When X-ray wave beam passes through with a thickness of L1Aluminum first part 21 when, the X-ray energy E of acquisition1=E0*EXP (-μ*L1).When wave beam passes through with a thickness of L2Aluminum second part 22 when, the X-ray energy E of acquisition2=E0*EXP(-μ* L2).Wherein, E0For without the X-ray energy of filter unit 2, E1With E2Different-thickness L is passed through to be corresponding1And L2Aluminum First part 21 and second part 22 X-ray energy, μ be attenuation coefficient of the X-ray in aluminium material.
Based on this, an embodiment of the present invention has specific thicknesses L by setting1And L2Filter unit 2, obtain two kinds The X-ray of different-energy, two kinds of X-rays are sensitive to the soft tissue decaying of highdensity bone tissue and low-density respectively, thus with One x-ray source, a detector realize dual intensity CBCT system and device.Dual intensity CBCT system and device compared with the background art, Structure is simple, and cost is relatively low.
Referring to shown in Fig. 4, an embodiment of the present invention provides a kind of method for reconstructing of dual intensity three-dimensional volumetric images, including step It is rapid:
A. arrange that filter unit 2, the filter unit 2 at least have different-thickness L in 1 front end of X-ray emission unit1With L2First part and second part;
B. the X that the transmitting unit 1 emits alternately is blocked respectively with the first part of different-thickness and second part to penetrate Line has high-energy E to generate1With low energy E2X-ray beam, and with the high-energy E1With low energy E2X-ray beam point It Zhao She not object to be measured;
C. the high energy projected image Pro_L for penetrating object to be measured is obtained1With low energy projected image Pro_L2, two width are projected Image carries out spatial registration, to the low energy projected image Pro_L2Carry out correction for attenuation;
D. the high energy projected image Pro_L is merged1With the low energy projected image Pro_L after correction for attenuation2, with Obtain fusion projected image;
E. according to the fusion backprojection image reconstruction dual intensity three-dimensional volumetric images.
Further, the step c includes:
By low energy projected image Pro_L2It is registrated to high energy projected image Pro_L1, it is assumed that joined by two images registration result Array at transformation matrix be T, then:
T(Pro_L2)→(Pro_L1) (1)
Wherein T (Pro_L2) and (Pro_L1) be consistent on spatial position, i.e. low energy projection P ro_L2Each of Pixel has been registered to high energy projection P ro_L from spatial position1Respective pixel position on.
If high energy projected image Pro_L1Middle any pixel P0(x0,y0) corresponding ray attenuation path is P1, P0(x0,y0) In T (Pro_L2) in respective pixel ray attenuation path be P2, due to Pro_L1And Pro_L2It is to drive to filter in rotary shaft 23 The projected image successively acquired in 2 rotary course of wave unit, therefore their ray attenuation path is different, i.e. P1And P2It is Two different ray attenuation paths.In order to keep the space-time consistency of high and low energy projected image, need to decay to projection ray Path is corrected.
Assuming that high energy projected image Pro_L1Corresponding effective rays energy is E1, effective linear attenuation coefficient is μ1, irradiation Sigmatron intensity before and after target and filter, dielectric (filtering thin slice) is respectively I0And I1, low energy projected image Pro_L2It is corresponding Effective rays energy be E2, effective linear attenuation coefficient is μ2, irradiate the low energy before and after target and filter, dielectric (filtering thin slice) X-ray intensity is respectively I0And I2, high energy projected image Pro_L1Pixel at middle any position (x, y) corresponds to X-ray across mesh Target is with a thickness of t, then
I1(x, y)=I0(x,y)*exp(-μ1*(t+L1)) (2)
It is available by formula (2):
T=-ln (I1(x,y)/I0(x,y))/μ1-L1 (3)
Then T (Pro_L2) at any position (x, y) pixel intensity value are as follows:
I2(x, y)=I0(x,y)*(exp(μ21)+I1(x,y)/I0(x,y)+(L1-L2)*μ2) (4)
T (Pro_L is corrected by formula (4)2) in pixel intensity value.
Further, step d includes:
In order to include simultaneously target high and low energy dampening information in the three-dimensional volumetric images of reconstruction, now to two kinds of energy Data for projection carry out fusion treatment, then in blending image at any position (x, y) pixel intensity value are as follows:
I (x, y)=λ * I1(x,y)+(1-λ)*I2(x,y) (5)
Wherein λ is weight coefficient, and 0 < λ < 1.As 0 < λ < 0.5, there are more low energy dampening informations in fusion projection, As 0.5 < λ < 1, there are more high energy dampening informations in fusion projection, it can be according to different application scenarios in practical application Select suitable λ value.
Further, step e includes: to rebuild dual intensity three-dimensional volumetric images DE-CBCT using FDK algorithm.
Finally it should be noted that property the above examples are only used to illustrate the technical scheme of the present invention and are not limiting.Although The invention is described in detail with reference to an embodiment, it should be appreciated by those of ordinary skill in the art that skill of the invention Art scheme is modified or replaced equivalently, and without departure from the spirit and scope of technical solution of the present invention, should all be covered at this In the scope of the claims of invention.

Claims (9)

1. being used for the bulb tube component of CBCT system characterized by comprising
For emitting the transmitting unit of X-ray;
The filter unit of first part and second part at least with different thickness, the filter unit can be respectively with first Part and second part block the X-ray of the transmitting unit transmitting, to generate the X-ray beam of different-energy.
2. the bulb tube component according to claim 1 for CBCT system, it is characterised in that:
The filter unit can rotatably be arranged in the front of the transmitting unit, and half has thickness L1, the other half has Thickness L2
3. the bulb tube component according to claim 2 for CBCT system, it is characterised in that:
The transmitting unit is bulb, and the bulb has circular X-ray emission hole;
The filter unit has filtering thin slice in a ring, and the width of the filtering thin slice is greater than or equal to the X of the bulb The diameter in ray emission hole.
4. the bulb tube component according to claim 3 for CBCT system, which is characterized in that the filter unit includes:
The rotary shaft being set on the bulb;And
The carrying tablet being set in the rotary shaft, the carrying tablet has to be engraved for the loop filtering thin slice annular to be arranged It is empty.
5. the bulb tube component according to claim 3 or 4 for CBCT system, it is characterised in that:
Revolving speed w=(2 π × the FPS/2)/second of the filter unit, wherein FPS is Image Acquisition frame frequency.
6. the method for reconstructing of dual intensity three-dimensional volumetric images characterized by comprising
A. arrange that filter unit, the filter unit at least have different-thickness L in X-ray emission unit front end1And L2First Part and second part;
B. the X-ray of the transmitting unit transmitting is alternately blocked with the first part of different-thickness and second part respectively, with Generating has high-energy E1With low energy E2X-ray beam, and with the high-energy E1With low energy E2X-ray beam respectively according to Penetrate object to be measured;
C. the high energy projected image Pro_L for penetrating object to be measured is obtained1With low energy projected image Pro_L2, by two width projected images Spatial registration is carried out, to the low energy projected image Pro_L2Carry out correction for attenuation;
D. the high energy projected image Pro_L is merged1With the low energy projected image Pro_L by correction for attenuation2, to obtain Merge projected image;
E. according to the fusion backprojection image reconstruction dual intensity three-dimensional volumetric images.
7. the method for reconstructing of dual intensity three-dimensional volumetric images according to claim 6, which is characterized in that the step c includes:
By low energy projected image Pro_L2It is registrated to high energy projected image Pro_L1, it is assumed that by two images registration result parameter group At transformation matrix be T, then:
T(Pro_L2)→(Pro_L1);
Assuming that high energy projected image Pro_L1Corresponding effective rays energy is E1, effective linear attenuation coefficient is μ1, irradiate target It is respectively I with the sigmatron intensity before and after filter, dielectric0And I1, low energy projected image Pro_L2Corresponding effective rays energy For E2, effective linear attenuation coefficient is μ2, the low energy X ray intensity irradiated before and after target and filter, dielectric is respectively I0And I2, high It can projected image Pro_L1Pixel at middle any position (x, y) corresponds to X-ray across target with a thickness of t, then
I1(x, y)=I0(x,y)*exp(-μ1*(t+L1));
I2(x, y)=I0(x,y)*(exp(μ21)+I1(x,y)/I0(x,y)+(L1-L2)*μ2)。
8. the method for reconstructing of dual intensity three-dimensional volumetric images according to claim 7, which is characterized in that the step d includes:
According to I (x, y)=λ * I1(x,y)+(1-λ)*I2(x, y) obtains the intensity of pixel at any position (x, y) in blending image Value, wherein λ is weight coefficient, and 0 < λ < 1.
9. the method for reconstructing of dual intensity three-dimensional volumetric images according to claim 8, which is characterized in that the step e includes: Dual intensity three-dimensional volumetric images are rebuild using FDK algorithm.
CN201910708583.6A 2019-08-01 2019-08-01 For the bulb tube component of CBCT system and the method for reconstructing of dual intensity three-dimensional volumetric images Pending CN110448320A (en)

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Application publication date: 20191115