CN110418633A - The method for removing keratotic plug - Google Patents

Abstract

The present invention provides one kind can not cause pain or excitement etc. to bear to skin, and the method for giving full play to the removal keratotic plug of excellent keratotic plug removal effect.It is using the pH value containing arginine (A) 0.8 mass % or more and at 20 mass % or less and 25 DEG C is 8.0 or more and 12.5 compositions below the present invention relates to a kind of method for removing keratotic plug.

Description

The method for removing keratotic plug

Technical field

The present invention relates to a kind of methods using the removal keratotic plug containing arginic composition.

Background technique

Keratotic plug is to be commonly in around nose equal sebum secretions amount compared with the pore of multiple location, and the object of pore is blocked in bolt shape Matter.

If ignored the keratotic plug is removed, there is skin that can become rough, and because keratotic plug physically supports pore Greatly, and pore tends to get bigger, in addition, worry the surface of keratotic plug also generate because oxidation caused by blackhead, damage the worry of aesthetic feeling.Into And these become the reason of acne etc., easily cause the skin problem such as measles or useless fellow.Therefore, keratotic plug, which is used as, keeps pore obvious One of the reason of, become the worry of numerous women.Therefore, exploitation now has various for removing the technology of such keratotic plug.

For example, in patent document 1, disclosing living containing the organic acids such as lactic acid and N- acyl taurines type anionic surface Property agent, and pH value be 3~5 composition of skin cleanser, can assign it is good blistering etc. and play keratotic plug removal effect. Also, in patent document 2, disclosing comprising the viscosity at specific nonionic surfactant, 30 DEG C is 15mPas or less Finish and the cleanser compositions of water-soluble polymer etc. disclose in patent document 3 containing carbon atom number 6~20 The facial cleanser of dibasic acid diester, these can generate keratotic plug removal effect by specific finish.

Also, in patent document 4, disclose the keratotic plug lytic agent for being combined with the basic amino acids such as arginine, show by The effect for blocking the keratotic plug dissolution of pore is excellent.

On the other hand, in patent document 5, a kind of sheet-type packs are disclosed, by multi-layered type penetrability keeping body and are contained Have and constituted with carboxyl etc. at the cosmetics of the high-molecular compound of alkali, by the way that the sheet-type packs are attached to skin, can be made Skin generates smooth feeling and moist feeling etc., and keratotic plug removal effect can also be played when from skin peeling.

[patent document 1] Japanese Patent Laid-Open 2015-113307 bulletin

[patent document 2] Japanese Patent Laid-Open 2011-12252 bulletin

[patent document 3] Japanese Patent Laid-Open 2007-230929 bulletin

[patent document 4] Japanese Patent Laid-Open 2004-75575 bulletin

[patent document 5] Japanese Patent Laid-Open 11-12127 bulletin

Summary of the invention

It is using containing arginine (A) 0.8 mass % or more and 20 matter the present invention relates to a kind of method for removing keratotic plug PH value at % or less and 25 DEG C of amount is 8.0 or more and 12.5 compositions below.

Also, containing 0.8 mass % of arginine or more and 20 mass % the present invention relates to a kind of keratotic plug removal composition Hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

Composition of skin cleanser documented by above patent document 1 only mainly passes through anionic property activating agent Cleaning force and remove the liquid sebum being present on skin, furfur and a part of keratotic plug outstanding.Documented by patent document 2,3 Only mainly pass through the dissolubility of finish by the cleanser compositions that specific finish etc. generates removal keratotic plug effect Remove a part of keratotic plug easily removed.These not can directly remove the technology of the dirt in pore, sufficiently remove keratotic plug Aspect still remain room for improvement.

When sufficiently removing keratotic plug, if using the arginic preparation of effective use as documented by patent document 4, though The effect of removal keratotic plug, but the side that promote the keratotic plug removal effect further can be improved compared with above patent document 1~3 Face still remains further room for improvement.

Also, the sheet-type packs of the effect of physical removal keratotic plug are played documented by patent document 5 can directly remove keratotic plug, it can Realize the significant decrease of clogging of pores, but in recent years, due to worrying that such physical removal means can damage skin, so it is expected The now keratotic plug removal technology that pain or excitement caused by skin etc. is reduced.

Therefore, it is desirable to occur not generating the burden such as pain or excitement to skin and excellent keratotic plug being given full play to and removed The new technology of effect.

Therefore, the present inventor has carried out sharp study in order to solve the above problems, as a result, it has been found that following method, thus complete At the present invention, pH value by using arginine is set as certain content and is controlled the combination for particular range by this method Object can not make skin generate pain or excitement of appropriateness etc., more effectively remove keratotic plug.

According to the present invention, can not to skin generate burden and be effectively removed keratotic plug, can significantly inhibit pore blocking and The opening of pore, it is obvious to be effectively prevented from pore.Also, can experience that the skin after removal keratotic plug is fine and smooth soft, bright really and Beautiful skin without blackhead.

Specific embodiment

Hereinafter, being described in detail to the present invention.

In the present specification, keratotic plug, which refers to, physiologically forms in the pore of the skin of people and blocks pore in bolt shape Substance.The main component of the keratotic plug is derived from the protein of cuticula and hair follicle, by these main component, i.e. comprising being originated from Cuo The protein of sore bacterium (acne bacteria) and staphylococcus aureus and protein from born of the same parents' device such as lysosome etc. The substance that protein and the lipid comprising triglycerides, free fatty acid and lipid peroxide etc. mix forms keratotic plug.

The method of removal keratotic plug of the invention be using containing arginine (A) 0.8 mass % or more and 20 mass % or less, And the pH value at 25 DEG C is 8.0 or more and 12.5 compositions below.In this way, containing ingredient (A) by using with specific quantity Arginine and pH value is controlled as the composition in particular range, the composition containing ingredient (A) can first permeated rapidly Into keratotic plug, dissolve out lipid to form keratotic plug etc. effectively.Also, the protein of usually cuticula etc. is easy agglutination, be not easy by The removal such as detergent, but by the way that the composition containing ingredient (A) applied to skin, can also be inhibited the agglutination of protein simultaneously, Therefore it can also effectively be removed it even if for the keratotic plug comprising protein.In turn, when being rinsed with water after application composition, water It is readily permeable to be disintegrated keratotic plug further into keratotic plug, therefore through the infiltration of water, it is flushable clean, so as to effectively from Keratotic plug of the pore removal comprising protein and lipid.Also, excellent keratotic plug removal effect can be played, and make to remove the hair after keratotic plug The dermalaxia on hole periphery becomes wet exquisiteness softness and bright beautiful skin.

For having both the viewpoint of agglutination inhibitory effect of keratotic plug removal effect and protein well, at used group It closes in object, the arginic content of ingredient (A) is 0.8 mass % or more, preferably 1.0 mass % or more, more preferably 2 matter Measure % or more, and then preferably 4 mass % or more, and then preferably 5 mass % or more.Also, just having both keratotic plug removal well For the viewpoint of effect and the agglutination inhibitory effect of protein, in used composition, the arginic content of ingredient (A) For 20 mass % hereinafter, preferably 16 mass % hereinafter, more preferably 14 mass % hereinafter, in turn be preferably 12 mass %, into And preferably 10 mass % or less.Then, in used composition, the arginic content of ingredient (A) is 0.8 mass % Above and 20 mass % are hereinafter, preferably 1.0~16 mass %, more preferably 2~14 mass %, and then preferably 4~12 matter Measure %, and then preferably 5~10 mass %.

It just gives full play to the viewpoint of the keratotic plug removal effect using mentioned component (A), also give full play to the agglutination of protein For the viewpoint of inhibitory effect and the pliability of promotion skin, the pH value at 25 DEG C of composition used in the present invention is 8.0 More than, preferably 8.5 or more, more preferably 8.8 or more, and then preferably 9.0 or more, and then preferably 9.2 or more, Jin Eryou 9.5 or more, and then preferably 9.8 or more, and then preferably 10.0 or more, and then preferably 10.2 or more are selected as, and then preferably It is 10.5 or more.Also, for may refrain from the viewpoint of the undue burden caused by skin, 25 DEG C of composition used in the present invention Under pH value be 12.5 hereinafter, preferably 12.2 hereinafter, more preferably 12.0 hereinafter, being in turn preferably 11.8 hereinafter, excellent in turn 11.5 are selected as hereinafter, being in turn preferably 11.2 hereinafter, being in turn preferably 11.0 or less.Then, composition used in the present invention 25 DEG C at pH value be 8.0~12.5, preferably 8.5~12.5, more preferably 8.5~12.2, and then preferably 8.8~ 12.2, and then preferably 9.0~12.0, and then preferably 9.2~11.8, and then preferably 9.5~11.8, and then preferably 9.8~11.8, and then preferably 10.0~11.5, and then preferably 10.2~11.2, and then preferably 10.5~11.2.

Furthermore composition used in the present invention can also suitably contain sodium hydroxide, sodium carbonate, sodium citrate, hydrochloric acid etc. PH adjuster, so as to adjust for above-mentioned pH value.

Furthermore for the viewpoint with regard to promoting keratotic plug cleaning force, mentioned component (A) is preferably in the form of free form is non-salt It is present in composition.That is, acid ingredient and ingredient (A) such as unneutralized fatty acid is not made preferably to form fatty acid salt Equal salt, and it is present at least part ingredient (A) in composition in the form of ingredient (A) is individual by free state.With regard to upper For stating viewpoint, in the ingredient (A) in used composition with free form, there are the contents of the content of person and ingredient (A) Mass ratio (content of content/ingredient (A) of the ingredient (A) of free state) be preferably 0.6 or more, more preferably 0.8 or more, And then preferably 0.9 or more, and then preferably 1.0.

Composition used in the present invention for promoting the viewpoint of foaming characteristic, can also contain in addition to containing mentioned component There is anionic surfactant (B).For further increasing the viewpoint of keratotic plug removal effect, preferably further containing has The anionic surfactant (B1) of carboxylic acid group and/or anionic surfactant (B2) with sulfonic group or sulfate group are made For anionic surfactant (B).

" carboxylic acid group " refers to also comprising carboxylic acid residues, the anion surface active with carboxylic acid group as the ingredient (B1) Agent can be enumerated one kind or two or more in fatty acid or its salt, ether carboxylic acid or its salt, N- acyl amino hydrochlorate.

" carboxylic acid group " of the anionic surfactant with carboxylic acid group of ingredient (B1) refers to also comprising carboxylic acid residues.Make It preferably include to be selected from fatty acid or its salt, ether carboxylic acid for the anionic surfactant with carboxylic acid group of the ingredient (B1) Or it is one kind or two or more in its salt and N- acyl amino hydrochlorate, it more preferably include ether carboxylic acid or its salt.

As the fatty acid or its salt that can be used as ingredient (B1), good foaming characteristic is just played, keratotic plug is further increased and goes For the viewpoint of effect, it is however preferred to have the fatty acid of the alkyl of the linear chain or branched chain of carbon atom number 10~22 or its salt, more The preferably fatty acid or its salt of the alkyl of the linear chain or branched chain with carbon atom number 10~18, and then preferably there is carbon atom The fatty acid of the alkyl of the straight chain of number 12~14 or its salt.Specifically, can enumerate selected from laruate, myristate, palm fibre It is one kind or two or more in palmitic acid hydrochlorate, stearate, behenic acid salt and these salt.Wherein, just viewpoint same as described above and Speech, be preferably selected from it is one kind or two or more in laruate, myristate and palmitate, more preferably be selected from laurel 1 kind in hydrochlorate and myristate or 2 kinds.

The salt of fatty acid salt as constituent (B1), be preferably selected from it is one kind or two or more in alkali metal and ammonium, It is one kind or two or more more preferably in alkali metal, and then preferably sodium salt.

Also, can also contain through unneutralized fatty acid in as ingredient (B1), such as in used composition The fatty acid salt formed with agent.With regard to promoting bubble amount, for the viewpoint of foaming characteristic, the neutralization ratio of the fatty acid is preferably 50~ 100%, more preferably 70~100%, and then preferably 90~100%, and then preferably 100%.As neutralizer, it is specific and Speech is preferably selected from a kind or 2 kinds in potassium hydroxide and sodium hydroxide.

As the ether carboxylic acid or its salt that can be used as ingredient (B1), can enumerate ether carboxylic acid represented by the following general formula (1) or its Salt.

R¹O(CH₂CH₂O)_mCH₂COOM¹…(1)

(in formula (1), R¹Indicate that the alkyl or alkenyl of carbon atom number 10~22, m indicate average 0.5~10 number, M¹It indicates Hydrogen atom, alkali metal, alkaline-earth metal, ammonium or organic ammonium.)

In general formula (1), as R¹, good foaming characteristic is just played, for the viewpoint for further increasing keratotic plug removal effect, The preferably alkyl of carbon atom number 12~16, the more preferably alkyl of carbon atom number 12~14, in addition, just viewpoint same as described above For, the average addition molal quantity m of ethylene oxide is preferably 2~5.

As M¹, hydrogen atom can be enumerated；The alkali metal such as sodium, potassium；The alkaline-earth metals such as calcium, magnesium；Ammonium；Monoethanolamine, diethyl Hydramine, triethanolamine etc. are originated from the ammonium of alkanolamine；Arginine, lysine etc. are originated from the ammonium etc. of basic amino acid.In these, just with For above-mentioned identical viewpoint, be preferably selected from it is one kind or two or more in sodium, potassium, triethanolamine and arginine, more preferably 1 kind in sodium and potassium or 2 kinds.

As the ether carboxylic acid or its salt, for viewpoint same as described above, specifically, it is preferable that for comprising being selected from polyoxy 1 kind or 2 kinds in ethylene laurel ether carboxylate, polyoxyethylene myristicin carboxylate and polyoxyethylene palm ether carboxylate with On, it preferably include a kind or 2 kinds in polyoxyethylene laurel ether carboxylate and polyoxyethylene myristicin carboxylate, into And preferably include polyoxyethylene laurel ether carboxylate.

Also, the commercially available product as the ether carboxylic acid or its salt, can enumerate AKYPO RLM 45CA (KAO. Corp. SA's manufacture), AKYPO LM 26C (KAO. Corp. SA's manufacture) etc..

Also, can also contain through unneutralized ether carboxylic acid in as ingredient (A1), such as in used composition The ether carboxylate formed with agent.With regard to promoting bubble amount, for the viewpoint of foaming characteristic, the neutralization ratio of the ether carboxylic acid is preferably 50~ 100%, more preferably 70~100%, and then preferably 90~100%, and then preferably 100%.As neutralizer, it is specific and Speech, a kind or 2 kinds be preferably selected from potassium hydroxide and sodium hydroxide.

As the acyl amino hydrochlorate that can be used as ingredient (B1), N- acylamino acid or its salt can be enumerated.It is good with regard to playing Foaming characteristic, for the viewpoint for further increasing keratotic plug removal effect, the acyl group of N- acylamino acid or its salt is preferably derived from The group of the fatty acid of saturations or undersaturated straight chain or branch with carbon atom number 4~30, being more preferably originated from has carbon The group of the fatty acid of the saturations or undersaturated straight chain or branch of atomicity 6~26, and then be preferably derived from carbon atom The group of the fatty acid of the saturations or undersaturated straight chain or branch of number 8~24.It as the fatty acid, can enumerate: octanoic acid, the last of the ten Heavenly stems Acid, lauric acid, myristic acid, palmitinic acid, stearic acid, oleic acid etc..In these fatty acid, for viewpoint same as described above, It is preferably selected from one or more of lauric acid, myristic acid, palmitinic acid and oleic acid, more preferably lauric acid.Also, N- acyl group ammonia The acyl group of base acid can also be the fatty acid mixed from above-mentioned fatty acid group, such as with coconut oil, palm-kernel oil etc. be original Expect resulting group.Wherein, preferably using coco-nut oil fatty acid or palm kernel fatty acid as the resulting group of raw material, more preferably Using coco-nut oil fatty acid as the resulting group of raw material.

Just play good foaming characteristic, for the viewpoint for further increasing keratotic plug removal effect, N- acylamino acid or its The neutral amino acid or be selected from glutamic acid and aspartic acid that the amino acid moiety of salt is preferably selected from glycine and alanine In acidic amino acid, more preferably acidic amino acid, and then preferably glutamic acid.Also, these amino acid moieties can be D body, L Any one of the mixture of body or D body and L body, preferably L body.

Above-mentioned N- acylamino acid or its salt can be used alone a kind, also can be used in combination two or more.Wherein, it is just promoted good For the viewpoint of the smoothness of good foaming characteristic and skin, preferably comprising being selected from N- lauroyl glutamate, N- myristoyl Base glutamic acid, N- cocoyl glutamic acid, N- PALM FATTY ACID glutamic acid, N- lauroyl aspartic acid, N- cocoyl are sweet One or more of propylhomoserin, N- cocoyl alanine and these salt, more preferably comprising selected from N- lauroyl glutamate, N- myristoyl glutamic acid, N- cocoyl glutamic acid, N- PALM FATTY ACID glutamic acid, N- lauroyl aspartic acid, N- One or more of cocoyl glycine and these salt, more preferably comprising being selected from N- lauroyl glutamate, N- Pork and beans One or more of cool acyl glutamic acid, N- cocoyl glutamic acid, N- lauroyl aspartic acid and these salt, Jin Eryou It is selected as comprising selected from one or more of N- cocoyl glutamic acid, N- lauroyl aspartic acid and these salt, Jin Ergeng It preferably include N- cocoyl glutamic acid or its salt.

As above-mentioned N- acylamino acid or the salt of its salt, the irritating viewpoint and accessibility to skin are just reduced For, it is preferably selected from the salt of one or more of alkali metal salt, triethanolamine salt and arginine salt, is more preferably selected from sodium The salt of one or more of salt, sylvite and triethanolamine salt, and then it is preferably selected from the salt of one or more of sodium salt and sylvite, And then preferably sodium salt.

Also, when using the situation of N- acylamino acid, it is preferable to use pass through alkali neutralization winner.With regard to promoted bubble amount, For the viewpoint of foaming characteristic, the neutralization ratio of N- acylamino acid is preferably 80~100%, more preferably 90~100%, Jin Eryou It is selected as 100%.Specifically, neutralizer is preferably selected from a kind or 2 kinds in potassium hydroxide and sodium hydroxide.

For playing the viewpoint of good foaming characteristic, in used composition, the content of ingredient (B1) is preferably 0.01 mass % or more, more preferably 0.03 mass % or more, more preferably 0.05 mass % or more, and then preferably 0.08 matter Measure % or more, and then preferably 0.10 mass % or more, and then preferably 0.2 mass % or more, and then preferably 0.3 mass % More than, and then preferably 0.5 mass % or more.Also, for the viewpoint for playing good keratotic plug removal effect, used In composition, the content of ingredient (B1) is preferably 5 mass % hereinafter, more preferably 4 mass % hereinafter, be preferably 3 matter in turn Measure % hereinafter, in turn be preferably 2 mass % hereinafter, in turn be preferably 1.5 mass % hereinafter, in turn be preferably 1.0 mass % with Under, and then preferably 0.8 mass % or less.Then, in used composition, the content of ingredient (B1) is preferably 0.01~ 5 mass %, more preferably 0.03~4 mass % are hereinafter, preferably 0.03~3 mass %, and then preferably 0.05~2 matter in turn Measure %, and then preferably 0.05~1.5 mass %, and then preferably 0.08~1.0 mass %, and then preferably 0.10~1.0 Quality %, and then preferably 0.2~0.8 mass %, and then preferably 0.3~0.8 mass %.

Furthermore about the content of ingredient (B1), for example use above-mentioned fatty acid or its salt as the situation of ingredient (B1) When, refer to fatty acid conversion amount, when using the situation of ether carboxylic acid or its salt or N- acylamino acid or its salt, refers to that acid changes Calculation amount.

In composition used in the present invention, excellent keratotic plug removal effect is just played, and keep good blistering For the viewpoint of property, the mass ratio ((A)/(B1)) of the content of the content and ingredient (B1) of ingredient (A) is preferably 1 or more, more excellent It is selected as 2 or more, and then preferably 5 or more, and then preferably 8 or more, and then preferably 10 or more.Also, just preventing from making skin At burden increase and to skin assign pliability viewpoint and promoted skin pliability viewpoint for, ingredient (A's) contains The mass ratio ((A)/(B1)) of amount and the content of ingredient (B1) is preferably 100 hereinafter, more preferably 70 hereinafter, being in turn preferably 60 Hereinafter, being in turn preferably 50 hereinafter, being in turn preferably 30 hereinafter, being in turn preferably 20 or less.Then, the content of ingredient (A) with The mass ratio ((A)/(B1)) of the content of ingredient (B1) is preferably 1~100, and more preferably 2~70, and then preferably 2~60, into And preferably 5~50, and then preferably 8~30, and then preferably 10~20.

" sulfonic group or the sulfate group " of the anionic surfactant with sulfonic group or sulfate group of ingredient (B2) Refer to also comprising sulfonic acid moieties or sulfuric ester residue.The anion table with sulfonic group or sulfate group as the ingredient (B2) Face activating agent, can enumerate selected from alkyl benzene sulphonate or its salt, alkyl sulfonic acid or its salt, olefin sulfonic acid or its salt, alkyl sulfonic acid or its Salt, acyl group isethionic acid or its salt, alkyl sulfate or its salt, alkyl ether sulphate or its salt, alkyl sulfosuccinic or its Salt, sulfo methyl ester or its salt, fatty acid alkanol amides sulfuric ester or its salt and monoacylglycerol sulfuric ester or its salt It is one kind or two or more in.As the salt of constituent (B2), it is preferably selected from sodium salt, sylvite, lithium salts, magnesium salts, ammonium salt Inorganic salts；And the organic amine salt selected from monoethanolamine salt, diethanolamine salt and triethanolamine salt.

In these, excellent keratotic plug removal effect is just played, and for keeping the viewpoint of good foaming characteristic, preferably Comprising selected from alkyl benzene sulphonate or its salt, acyl group isethionic acid or its salt, alkyl sulfate or its salt, alkyl ether sulphate or its It is one kind or two or more in salt, olefin sulfonic acid or its salt and alkyl sulfonic acid or its salt, more preferably comprising being selected from alkylsurfuric acid 1 kind or 2 kinds in ester or its salt, alkyl ether sulphate or its salt, olefin sulfonic acid or its salt and alkyl sulfonic acid or its salt with On, and then preferably comprising in alkyl ether sulphate or its salt, olefin sulfonic acid or its salt and alkyl sulfonic acid or its salt It is one kind or two or more, and then preferably comprising a kind or 2 kinds in olefin sulfonic acid or its salt and alkyl sulfonic acid or its salt More than, and then preferably comprising in alkyl sulfate salt, alkyl ether sulphate salts, alkenyl sulfonate and alkylsulfonate It is one kind or two or more.

As the alkyl sulfate salt that can be used as ingredient (B2), alkyl sulfate represented by the following general formula (2) can be enumerated Salt.

R²OSO₃M²…(2)

(in formula (2), R²Indicate the aliphatic alkyl of carbon atom number 8~22, M²Indicate selected from alkali metal, alkaline-earth metal, Cation in ammonium, alkylammonium, alkanol ammonium and Gluconic Acid Ammonium salt.) in general formula (2), as R², just play excellent keratotic plug removal Effect, and for keeping the viewpoint of good foaming characteristic, the preferably aliphatic alkyl of carbon atom number 8~18, more preferably The aliphatic alkyl of carbon atom number 8~16, and then the aliphatic alkyl of preferably carbon atom number 10~16.In turn, preferably carbon The alkyl or alkenyl of atomicity 8~16, the more preferably alkyl or alkenyl of carbon atom number 10~16, and then preferably carbon atom number 10~14 alkyl or alkenyl.

As M², for viewpoint same as described above, preferably alkali metal, ammonium, more preferably alkali metal, and then preferably For sodium salt.

As the alkyl sulfate salt, NaLS, triethanolamine lauryl sulfate, laurel can be specifically enumerated Base ammonium sulfate, myristyl sulfate, cetyl sulfate, stearyl sodium sulphate, oleyl sulfate, oil base sulfuric acid triethanolamine Deng.In these, preferably comprising a kind in NaLS, triethanolamine lauryl sulfate and Texapon Special More than.1 kind to can be used alone in these compounds, also can be used in combination two or more.

Also, the commercially available product as the alkyl sulfate salt, such as Emal 0S (KAO. Corp. SA's manufacture, lauryl sulphur can be enumerated Sour sodium), Emal 10PT (KAO. Corp. SA manufacture, NaLS), Emal TD (KAO. Corp. SA's manufacture, lauryl sulfate three Ethanol amine), Emal AD-25R (KAO. Corp. SA manufacture, Texapon Special) etc..

As the alkyl ether sulphate salts that can be used as ingredient (B2), alkyl ether sulphur represented by the following general formula (3) can be enumerated Acid esters salt.

R³O(CH₂CH₂O)_nSO₃M³…(3)

(in formula (3), R³Indicate the aliphatic alkyl of carbon atom number 8~22, M³Indicate selected from alkali metal, alkaline-earth metal, Cation in ammonium, alkylammonium, alkanol ammonium and Gluconic Acid Ammonium salt, n indicate average addition molal quantity, are 0.5~20.)

In general formula (3), as R³, excellent keratotic plug removal effect is just played, and keep the viewpoint of good foaming characteristic For, the preferably aliphatic alkyl of carbon atom number 8~18, the more preferably aliphatic alkyl of carbon atom number 8~16, Jin Eryou It is selected as the aliphatic alkyl of carbon atom number 10~16.In turn, the preferably alkyl or alkenyl of carbon atom number 8~16, more preferably The alkyl or alkenyl of carbon atom number 10~16, and then the alkyl or alkenyl of more preferably carbon atom number 10~14.

For viewpoint same as described above, n is preferably 0.5 or more, in addition, preferably 12 hereinafter, preferably 5 hereinafter, into And preferably 4 hereinafter, in turn be more preferably 2 or less.Specific n's ranges preferably from 0.5~12, more preferably 0.5~5, into And preferably 0.5~4, and then more preferably 0.5~2.

For viewpoint same as described above, as M³, preferably alkali metal, ammonium, more preferably alkali metal, and then preferably For sodium salt.

As the alkyl ether sulphate salts, specifically, can enumerate selected from polyoxyethylene (1) laurel ether sodium sulfate, polyoxy Ethylene (1) laurel ether ammonium sulfate, polyoxyethylene (1) myristicin sodium sulphate, polyoxyethylene (2) laurel ether sodium sulfate and polyoxy It is one kind or two or more in ethylene (2) myristicin sodium sulphate.In these, preferably comprising being selected from polyoxyethylene (1) laurel ether One or more of sodium sulphate, polyoxyethylene (1) laurel ether ammonium sulfate and polyoxyethylene (2) laurel ether sodium sulfate.Furthermore at this In specification, the numerical value in the bracket of these compounds refers to the average addition molal quantity of ethylene oxide.

Also, the commercially available product as the alkyl ether sulphate salts, such as Emal 125HP can be enumerated (KAO. Corp. SA's manufacture, gathers Ethylene oxide (1) laurel ether sodium sulfate), Emal 125A (KAO. Corp. SA manufacture, polyoxyethylene (1) laurel ether ammonium sulfate), Emal 227 (KAO. Corp. SA's manufacture, polyoxyethylene (2) laurel ether sodium sulfates) etc..

As the olefin sulfonic acid or its salt that can be used as ingredient (B2), it is however preferred to have the carbon atom number 12~22 of double bond it is straight Chain hydrocarbon, the more preferably straight-chain hydrocarbons of the carbon atom number 12~18 with double bond and for sulfo group be bonded in the carbon atom except end with Olefin sulfonic acid made of outer any carbon atom or its salt.And then the straight chain of the preferably carbon atom number 12~18 with double bond There are more than 70 mass % and sulfo group is bonded in except end on 3 or more interior locations in straight-chain hydrocarbons for hydrocarbon and position of double bond Olefin sulfonic acid made of any carbon atom other than the carbon atom at end or its salt.

The olefin sulfonic acid of these carbon atom numbers 12~22 or its salt can be used alone a kind, also can be used in combination two or more, For controllable foaming characteristic, the viewpoint of alveolar substance, two or more preferably is applied in combination according to purpose is used.In turn, it just blisters For property, the viewpoint of alveolar substance, preferably the olefin sulfonic acid of the olefin sulfonic acid of carbon atom number 16 or its salt or carbon atom number 18 or Its salt.Also, preferably by the olefin sulfonic acid or its salt of the olefin sulfonic acid of these carbon atom numbers 16 or its salt and carbon atom number 18 with The form of mixture uses, the olefin sulfonic acid or its salt of carbon atom number 16 at this time and the olefin sulfonic acid or its salt of carbon atom number 18 Mass ratio be preferably 1/9~9/1, more preferably 2/8~8/2, and then preferably 5/5~2/8.By using these mixing Sense of touch during rinsing can be improved in object.

As the salt for constituting alkenyl sulfonate, can enumerate: the alkali metal such as sodium, potassium；The alkaline-earth metals such as calcium, magnesium；Ammonium；It is originated from The salt that the organic ammonium of monoethanolamine, diethanol amine, triethanolamine etc. is constituted.In these, just acquired viewpoint in the market For, preferably alkali metal salt, ammonium salt.

As the alkyl sulfonic acid or its salt that can be used as ingredient (B2), preferably the hydroxyalkylated sulfonic acid of carbon atom number 12~22 or Its salt, the more preferably hydroxyalkylated sulfonic acid of carbon atom number 12~22 or its salt and for sulfo group be bonded in the carbon atom except end with Hydroxyalkylated sulfonic acid made of outer any carbon atom or its salt, in turn, preferably the hydroxyalkylated sulfonic acid of carbon atom number 12~18 or Its salt and hydroxyalkylated sulfonic acid made of any carbon atom in addition to the carbon atom of end or its salt are bonded in for sulfo group.In turn Preferably the straight-chain hydrocarbons of carbon atom number 12~18 and any carbon atom and sulphur in addition to the carbon atom of end are bonded in for hydroxyl Base is bonded in hydroxyalkylated sulfonic acid made of any carbon atom in addition to the carbon atom of end or its salt.

The hydroxyalkylated sulfonic acid of these carbon atom numbers 12~22 or its salt can be used alone a kind, also can be used in combination 2 kinds with On, so that it may for controlling foaming characteristic, the viewpoint of alveolar substance, two or more preferably is applied in combination according to purpose is used.In turn, For foaming characteristic, the viewpoint of alveolar substance, the preferably hydroxyalkylated sulfonic acid of carbon atom number 16 or its salt or the hydroxyl alkane of carbon atom number 18 Base sulfonic acid or its salt.Also, preferably by the hydroxyalkylated sulfonic acid of these carbon atom numbers 16 or the hydroxyalkyl of its salt and carbon atom number 18 Sulfonic acid or its salt use as a mixture, hydroxyalkylated sulfonic acid or its salt and the carbon atom number 18 of carbon atom number 16 at this time Mass ratio (the hydroxyalkylated sulfonic acid of the hydroxyalkylated sulfonic acid of carbon atom number 16 or its salt/carbon atom number 18 of hydroxyalkylated sulfonic acid or its salt Or its salt) it is preferably 9/1~1/9, more preferably 8/2~2/8, and then preferably 5/5~2/8.By using these mixing Sense of touch during rinsing can be improved in object.

As the salt for constituting alkylsulfonate, can enumerate: the alkali metal such as sodium, potassium；The alkaline-earth metals such as calcium, magnesium；Ammonium；It is originated from The salt that the organic ammonium of monoethanolamine, diethanol amine, triethanolamine etc. is constituted.In these, just acquired viewpoint in the market For, preferably alkali metal salt, ammonium salt.

As ingredient (B2), olefin sulfonic acid or its salt or alkyl sulfonic acid or any one of its salt can be used, it can also be by this A little olefin sulfonic acids or its salt and alkyl sulfonic acid or its salt use as a mixture.In the feelings of the mixture using these When shape, the mass ratio (olefin sulfonic acid or its salt/alkyl sulfonic acid or its salt) of olefin sulfonic acid or its salt and alkyl sulfonic acid or its salt is excellent It is selected as 5/95~50/50, more preferably 10/90~30/70.

Furthermore olefin sulfonic acid or its salt, alkyl sulfonic acid or its salt can for example pass through Japanese Patent Laid-Open 2015-28123 institute The method of record manufactures.

For playing the viewpoint of good foaming characteristic, in composition used in the present invention, the content of ingredient (B2) Preferably 0.01 mass % or more, more preferably 0.02 mass % or more, and then preferably 0.05 mass % or more, and then preferably For 0.08 mass % or more, and then preferably 0.10 mass % or more, and then preferably 0.3 mass % or more, and then preferably 0.5 mass % or more, and then preferably 1.0 mass % or more.Increase also, just preventing from bearing caused by skin, plays excellent Keratotic plug removal effect viewpoint and promoted foaming characteristic viewpoint for, in used composition, the content of ingredient (B2) Preferably 15 mass % hereinafter, more preferably 10 mass % hereinafter, in turn be preferably 8 mass %, and then preferably 5 mass % with Under, and then preferably 4 mass % hereinafter, be preferably 3 mass % or less in turn.Then, in used composition, ingredient (B2) content is preferably 0.01~15 mass %, more preferably 0.01~10 mass %, and then preferably 0.02~8 matter %, and then preferably 0.05~5 mass %, and then preferably 0.05~4 mass %, and then preferably 0.08~4 mass % are measured, And then preferably 0.10~4 mass %, and then preferably 0.3~4 mass %, and then preferably 0.5~4 mass %, Jin Eryou It is selected as 1.0~3 mass %.

In composition used in the present invention, excellent keratotic plug removal effect is just played, and keep good blistering For the viewpoint of property, the mass ratio ((A)/(B2)) of the content of the content and ingredient (B2) of ingredient (A) is preferably 0.10 or more, more Preferably 0.15 or more, and then preferably 0.20 or more, and then preferably 0.22 or more, and then preferably 0.25 or more, preferably It is 0.50 or more, and then preferably 0.8 or more, and then preferably 1.0 or more.Also, excellent keratotic plug removal effect is just played, and And for keeping the viewpoint of good foaming characteristic, the mass ratio ((A)/(B2)) of the content of the content and ingredient (B2) of ingredient (A) Preferably 100 hereinafter, more preferably 60 hereinafter, in turn be preferably 50 hereinafter, in turn be preferably 40 hereinafter, in turn be preferably 30 with Under, so preferably 20 hereinafter, in turn be preferably 10 hereinafter, in turn be preferably 5 or less.Then, the content and ingredient of ingredient (A) (B2) mass ratio ((A)/(B2)) of content is preferably 0.1~100, and more preferably 0.1~70, and then preferably 0.15~ 60, and then preferably 0.20~50, and then preferably 0.22~40, and then preferably 0.22~30, and then preferably 0.22~ 20, and then preferably 0.25~10, and then preferably 0.5~10, and then preferably 0.8~5, and then preferably 1.0~5.

In composition used in the present invention, it is possible to use the anionic surface other than mentioned component (B1) and (B2) is living Property agent.As the anionic surfactant other than ingredient (B1) and (B2), phosphate-type surfactant can be enumerated, it is specific and Speech, can enumerate alkyl phosphate salt, ether phosphates, alkylaryl ether phosphate, fatty acid amide ether phosphoric acid Salt etc..

The content of anionic surfactant other than ingredient (B1) and (B2) is also possible to by used composition Dosage form influences, and just plays excellent keratotic plug removal effect, and for keeping the viewpoint of good foaming characteristic, in the composition In, preferably 0.01 mass % or more, more preferably 0.05 mass % or more, and then preferably 0.1 mass % or more, and preferably For 10 mass % hereinafter, more preferably 5 mass % hereinafter, be preferably 1 mass % hereinafter, being in turn preferably 0.5 mass % in turn Below.

For playing the viewpoint of good foaming characteristic and playing the viewpoint of excellent keratotic plug removal effect, used In composition, total content of ingredient (B) is preferably 0.01 mass % or more, more preferably 0.02 mass % or more, Jin Eryou It is selected as 0.05 mass % or more, and then preferably 0.10 mass % or more, and then preferably 0.3 mass % or more, and then preferably For 0.5 mass % or more.Also, for preventing from bearing the viewpoint of increase caused by skin, in used composition, at Total content of point (B) be preferably 30 mass % hereinafter, more preferably 20 mass % hereinafter, be in turn preferably 15 mass % with Under, and then preferably 12 mass % hereinafter, be preferably 8 mass % hereinafter, being in turn preferably 4 mass % or less in turn.Then, In In used composition, total content of ingredient (B) is preferably 0.01~30 mass %, more preferably 0.02~20 matter Measure %, and then preferably 0.05~15 mass %, and then preferably 0.10~12 mass %, and then preferably 0.3~8 matter Measure %, and then preferably 0.5~4 mass %.

With regard to playing good sebum spatter property and makeup removing, and for further increasing the viewpoint of keratotic plug removal effect, this hair Composition used in bright preferably further contains nonionic surfactant (C).

Preferably it is containing HLB for improving the viewpoint of sebum spatter property and keratotic plug removal effect as ingredient (C) 11 or more nonionic surfactant (C1).The HLB of the ingredient (C1) is 11 or more, preferably 12 or more, more preferably 13 More than, and preferably 20 hereinafter, more preferably 19 hereinafter, in turn be preferably 18 or less.Also, the HLB of ingredient (C1) is 11 or more, Preferably 11~20, more preferably 12~19, and then preferably 13~18.

Herein, HLB (the balance < Hydrophilic- of hydrophilic-lipophilic of nonionic surfactant Lypophilic Balance >) indicate the molecular weight of hydrophilic group part shared in the total molecular weight of surfactant, It is found out by the formula of lattice Lifei (Griffin) below.

HLB=20 × (molecular weight/surfactant molecular weight of the hydrophilic base portion in surfactant molecule)

It as the nonionic surfactant of ingredient (C1), such as can enumerate: polyglyceryl fatty acid ester, polyethylene glycol fatty Acid esters, polyglyceryl fatty acid ester, polyoxyethylene polyoxypropylene glycol, polyoxyethylene sorbitan carboxylic ester, polyoxy Ethylene Span, Emulsifier EL-60, Crodaret, Crodaret fatty acid Ester, polyoxyethylene alkyl ether, polyoxyethylene alkyl ether aliphatic ester, sucrose fatty ester, alkyl poly glucoside, (poly-) alkyl Glycerin ether etc..

Wherein, with regard to promoted sebum spatter property, washability viewpoint for, preferably comprising selected from polyglyceryl fatty acid ester, Cithrol, polyglyceryl fatty acid ester, polyoxyethylene sorbitan carboxylic ester, polyethylene glycol hydrogenated castor It is one kind or two or more in sesame oil aliphatic ester, polyoxyethylene alkyl ether and alkyl poly glucoside, more preferably comprising being selected from 1 in cithrol, polyoxyethylene alkyl ether, polyoxyethylene sorbitan carboxylic ester and alkyl poly glucoside Kind or two or more.

As the commercially available product of polyoxyethylene sorbitan carboxylic ester, preferably polyoxyethylene (6) lauric acid sorbitol anhydride (RHEODOL TW-L106 (HLB13.3), KAO. Corp. SA's manufacture) etc..

As the commercially available product of cithrol, preferably mono laurate macrogol ester (12EO) (EMANON 112 (HLB13.7), KAO. Corp. SA's manufacture) etc..

As the commercially available product of polyoxyethylene alkyl ether, preferably polyoxyethylene (21) laurel ether (EMULGEN 121-G (HLB16.6), KAO. Corp. SA manufacture), polyoxyethylene (20) 2- hexyl last of the ten Heavenly stems ether (EMULGEN 1620G (HLB14), KAO. Corp. SA Manufacture), polyoxyethylene (16) laurel ether (EMULGEN 116 (HLB15.8), KAO. Corp. SA manufacture), polyoxyethylene (9) laurel ether (EMULGEN 109P (HLB13.6), KAO. Corp. SA's manufacture), polyoxyethylene (20) octyldodecyl ether (EMULGEN 2020G (HLB13.3), KAO. Corp. SA manufacture), polyoxyethylene (25) octyldodecyl ether (EMULGEN 2025G (HLB14.1), flower The manufacture of princes and dukes department) etc..

As the commercially available product of alkyl poly glucoside, preferably decyl glucoside (MYDOL 10 (HLB15.7), flower king Company's manufacture), lauryl glucoside (MYDOL 12 (HLB17), KAO. Corp. SA manufacture) etc..

Nonionic as ingredient (C), for playing the viewpoint of more good makeup removing, preferably containing HLB less than 11 Surfactant (C2).The HLB of ingredient (C2) less than 11, preferably 10 hereinafter, more preferably 9 hereinafter, and preferably 4 or more, More preferably 5 or more HLB, and then preferably 6 or more HLB, in addition, the HLB of ingredient (C2) is less than 11, and preferably 4~10, it is more excellent It is selected as 5~10, and then preferably 6~9.

It as the nonionic surfactant of ingredient (C2), such as can enumerate: the ethylene glycol rouge such as ethylene glycol monostearate The cithrols such as fat acid esters, polyethylene glycol (2) monostearate, polyethylene glycol (5) decyl pentadecyl ether etc. are poly- The polyethylene glycol such as the Cremophor RH40s such as ethylene glycol alkyl ether, the different laurate of polyethylene glycol (5) rilanit special list It is surfactant；Methyl glycol fatty acid ester, polypropylene glycol fatty acid esters, propylene glycol alkyl ether, polypropylene glycol alkyl ether, the third two The propylene glycol such as ethylene oxide derivant of alcohol alkyl ether system surfactant；The fatty acid glycerides such as glycerol monoisostearate； The glycerol alkyl ethers such as the different stearyl ether of glycerol list；The sorbitan carboxylic esters such as sorbitan monostearate；Single isostearic acid is poly- Polyglyceryl fatty acid esters such as glyceride etc..

Wherein, preferably comprising one kind or two or more in polyoxyethylene alkyl ether and polyglyceryl fatty acid ester.

As the commercially available product of polyoxyethylene alkyl ether, preferably polyoxyethylene (2) laurel ether (EMULGEN 102 (HLB6.4), KAO. Corp. SA manufactures), it is polyoxyethylene (3) laurel ether (EMULGEN 103 (HLB8.3), KAO. Corp. SA manufacture), poly- Ethylene oxide (5) laurel ether (EMULGEN 105 (HLB10), KAO. Corp. SA's manufacture) etc..

As the commercially available product of polyglyceryl fatty acid ester, preferably isostearic acid polyglycerol ester (Cosmol 41V (HLB8), The manufacture of Nisshin OilliO Group company) etc..

In composition used in the present invention, for playing the viewpoint of good sebum spatter property and makeup removing, ingredient (C1) content of the nonionic surfactant of HLB11 or more and the non-ionic surface active of the HLB less than 11 of ingredient (C2) The mass ratio ((Cl)/(C2)) of the content of agent is preferably 0.1 or more, and more preferably 0.6 or more, and then preferably 0.8 or more, into And preferably 1.5 or more, and then preferably 2.5 or more, in addition, preferably 25 hereinafter, more preferably 20 hereinafter, be preferably 16 in turn Hereinafter, being in turn preferably 14 hereinafter, being in turn preferably 12 or less.Also, the non-ionic surface active of the HLB11 or more of ingredient (C1) The mass ratio ((C1)/(C2)) of the content of nonionic surfactant of the HLB less than 11 of the content and ingredient (C2) of agent is preferred Be 0.1~25, more preferably 0.6~20, and then preferably 0.8~16, and then preferably 1.5~14, and then preferably 2.5~ 12。

With regard to the good sebum spatter property of performance and makeup removing, for the viewpoint for further increasing keratotic plug removal effect, in this hair In composition used in bright, the content of ingredient (C) is preferably 0.1 mass % or more, more preferably 0.5 mass % or more, more Preferably 0.7 mass % or more, and then preferably 0.8 mass % or more, in addition, preferably 30 mass % are hereinafter, more preferably 25 Quality % hereinafter, be preferably 20 mass % hereinafter, being in turn preferably 15 mass % or less in turn.Also, used in the present invention In composition, the content of ingredient (C) is preferably 0.1~30 mass %, more preferably 0.5~25 mass %, and then preferably 0.7 ~20 mass %, and then preferably 0.8~15 mass %.

In composition used in the present invention, excellent keratotic plug removal effect is just played, and keep good sebum clear For the viewpoint of clean property, the mass ratio ((A)/(C)) of the content of the content and ingredient (C) of ingredient (A) is preferably 0.01 or more, more Preferably 0.02 or more, and then preferably 0.03 or more.Also, just preventing from making skin in composition used in the present invention At burden increase, for the viewpoint for playing excellent keratotic plug removal effect, the content of the content and ingredient (C) of ingredient (A) Mass ratio ((A)/(C)) be preferably 25 hereinafter, more preferably 20 hereinafter, in turn be preferably 10 hereinafter, in turn be preferably 8 hereinafter, Preferably 5 hereinafter, be preferably 3 hereinafter, being in turn preferably 1.0 hereinafter, being in turn preferably 0.8 or less in turn in turn.Then, at this In composition used in inventing, the mass ratio ((A)/(C)) of the content of the content and ingredient (C) of ingredient (A) is preferably 0.01 ~25, more preferably 0.01~20, and then preferably 0.01~10, more preferably 0.02~8, and then preferably 0.02~5, into And preferably 0.02~3, and then preferably 0.02~1.0, preferably 0.03~0.8.

It is used in the present invention with regard to playing excellent keratotic plug removal effect, and for skin assigns the viewpoint of moist feeling Composition preferably further contains polyalcohol (D).As the polyalcohol of the ingredient (D), can enumerate: ethylene glycol, diethylene glycol, The dihydric alcohols such as polyethylene glycol, propylene glycol, dipropylene glycol, polypropylene glycol, isoprene, hexylene glycol, 1,3 butylene glycol；Glycerol, two The alcohol more than ternarys such as glycerol, triglycerin, four glycerol, six glycerol, ten glycerol, trimethyl propanol；Antierythrite, pentaerythrite, Dipentaerythritol, glucose, mannose, galactolipin, sucrose, fructose, maltose, trehalose, maltitol, xylitol, inositol, The sugar such as sorbitol anhydride, sorbierite or sugar alcohol etc..Wherein, moist feeling just is assigned to skin, and plays excellent keratotic plug removal effect Viewpoint for, the ingredient (D) is preferably comprising selected from ethylene glycol, diethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, poly- Propylene glycol, isoprene, hexylene glycol, 1,3 butylene glycol, glycerol, two glycerol, triglycerin, four glycerol, six glycerol, ten glycerol, three Methylpropanol, antierythrite, pentaerythrite, dipentaerythritol, glucose, mannose, galactolipin, sucrose, fructose, maltose, It is one kind or two or more in maltitol, xylitol, inositol, sorbitol anhydride and sorbierite, preferably comprising selected from dipropylene glycol, 1 kind in 1,3 butylene glycol, glycerol, sorbierite and mannitol or 2 kinds.

With regard to playing excellent keratotic plug removal effect, and for skin assigns the viewpoint of moist feeling, in used combination In object, the content of ingredient (D) is preferably 0.5 mass % or more, more preferably 1.0 mass % or more, is 3 mass % or more, 5 matter Measure % or more, 8 mass % or more, 10 mass % or more, in addition, preferably 40 mass % hereinafter, more preferably 35 mass % hereinafter, And then preferably 30 mass % hereinafter, be preferably 25 mass % hereinafter, being in turn preferably 20 mass % or less in turn.Then, In In used composition, the content of ingredient (D) is preferably 0.5~40 mass %, more preferably 1.0~35 mass %, in turn Preferably 3~30 mass %, and then preferably 5~25 mass %, and then preferably 8~20 mass %, and then preferably 10~ 20 mass %.

In composition used in the present invention, excellent keratotic plug removal effect is just played, and assign moist feeling to skin Viewpoint for, the mass ratio ((A)/(D)) of the content of the content and ingredient (D) of ingredient (A) is preferably 0.01 or more, more preferably It is 0.02 or more, and then preferably 0.03 or more, and then preferably 0.04 or more, and then preferably 0.05 or more.Also, in this hair In composition used in bright, excellent keratotic plug removal effect is just played, and for skin assigns the viewpoint of moist feeling, ingredient (A) mass ratio ((A)/(D)) of content and the content of ingredient (D) is preferably 6 hereinafter, more preferably 3 hereinafter, being preferably in turn 1.0 hereinafter, be preferably 0.6 hereinafter, being in turn preferably 0.5 or less in turn.Then, in composition used in the present invention, at The mass ratio ((A)/(D)) of the content of (A) and the content of ingredient (D) is divided to be preferably 0.01~6, more preferably 0.02~3, in turn Preferably 0.03~1.0, and then preferably 0.04~0.6, and then preferably 0.05~0.5.

With regard to playing excellent keratotic plug removal effect, and inhibit vertical stream when smearing, for the viewpoint for promoting ageing stability, Composition used in the present invention preferably further contains water soluble polymer (E).The water soluble polymer of ingredient (E) is logical Arbitrary substance used in normal composition.Specifically, may refrain from vertical stream when smearing, the sight of ageing stability is promoted For point, as preferred water soluble polymer, it can enumerate: carboxy vinyl polymer, acrylic acid-(methyl) alkyl acrylate Copolymer, addition have the cellulose etc. of ethoxy or hydroxypropyl.As carboxy vinyl polymer, such as Carbopol can be used 980, the commercially available products such as Carbopol 981 (the above are the manufactures of Lubrizol Advanced Materials company), as propylene Acid-(methyl) alkyl acrylate copolymer, such as Pemulen TR-1, Pemulen TR-2, Carbopol can be used ETD2020、Carbopol 1382、Carbopol 1342、Carbopol Ultrez 10、Carbopol Ultrez 20、 Carbopol Ultrez 21 (the above are the manufactures of Lubrizol Advanced Materials company), AQUPEC HV-501ER Commercially available products such as (Sumitomos refine company manufacture).

Also, it is that a part of the hydrogen atom in the hydroxyl of cellulose is substituted that addition, which has the cellulose of ethoxy or hydroxypropyl, For ethoxy or hydroxypropyl, there can also be the substituent group other than these.Specifically, can enumerate: hydroxyethyl cellulose, hydroxypropyl Cellulose, hydroxyethylmethylcellulose, hydroxypropyl methyl cellulose etc..These are to obtain as follows: make cellulose with it is severe Property sodium reaction and alkali cellulose is made, then acted on itself and chloromethanes, chloroacetic acid, ethylene oxide, propylene oxide etc., Hydrogen atom in the hydroxyl of cellulose is substituted by ethoxy, hydroxypropyl, methyl, carboxymethyl etc..

It may refrain from vertical stream when smearing, for the viewpoint for promoting ageing stability, the average substitution degree of these celluloses is big In 0, more preferably 0.5 or more, and preferably 3 hereinafter, more preferably 2 or less.Also, for same viewpoint, weight average Molecular weight is preferably 200,000 or more, more preferably 500,000 or more, more preferably 650,000 or more, and preferably 3, 000,000 hereinafter, more preferably 2, and 000,000 hereinafter, more preferably 1, and 600,000 or less.Furthermore it is in the present invention, average Degree of substitution is found out by nuclear magnetic resonance (NMR), weight average molecular weight be by the way that standard substance is set as polyethylene oxide, It is measured using gel permeation chromatography (GPC)-multiple angle laser light scattering detection device (MALLS) system.

There are the cellulose of ethoxy or hydroxypropyl, preferably hydroxyethyl cellulose, hydroxypropyl methyl cellulose as addition, The cellulose that preferably average substitution degree is 0.5~2 and weight average molecular weight is 650,000~1,600,000.

There is the cellulose of ethoxy or hydroxypropyl as addition, for example, CELLOSIZE can be used in hydroxyethyl cellulose QP52000H (manufacture of The Dow Chemical company), HEC Daicel SE400, SE500, SE600, SE850, SE900 Commercially available products such as (the above are the manufactures of Daicel FineChem company)；Hydroxypropyl methyl cellulose can be used METOLOSE 60SH, 65SH (the above are the manufactures of chemical industrial company, SHIN-ETSU HANTOTAI), BENECEL E50, E4M, E10M, F4MC, K99C, K4M, K15M, The commercially available products such as K35M, K100M, K200M (the above are the manufactures of ASHLAND company).

With regard to playing excellent keratotic plug removal effect, and inhibit vertical stream when smearing, for the viewpoint for promoting ageing stability, In used composition, the content of ingredient (E) is preferably 0.01 mass % or more, more preferably 0.05 mass % or more, And then preferably 0.10 mass % or more, and then preferably 0.15 mass % or more, in addition, preferably 3 amount % are hereinafter, more preferably 2 mass % hereinafter, be preferably 1.0 mass % hereinafter, being in turn preferably 0.8 mass % or less in turn.Then, at used group It closes in object, the content of ingredient (E) is preferably 0.01~3 mass %, more preferably 0.05~2 mass %, and then preferably 0.10 ~1.0 mass %, and then preferably 0.15~0.8 mass %.

It is used in the present invention with regard to playing excellent keratotic plug removal effect, and for skin assigns the viewpoint of moist feeling Composition is preferably further containing a kind or 2 in neutral amino acid, betaine type compound and edetate Kind or more (F).It as the neutral amino acid of the ingredient (F), such as can enumerate: glycine, sarcosine, Serine, β-the third ammonia Acid, aminobutyric acid etc. are the substance other than ingredient (H), can enumerate trimethylglycine, front three as betaine type compound Base serine, hydroxyethyl dimethyl glycine, monoethanol-C5- carboxybetaine etc..Wherein, excellent keratotic plug removal is just played For the viewpoint of effect, as the ingredient (F), preferably comprising being selected from trimethylglycine, trimethyl serine, ethoxy two It is one kind or two or more in methylglycine and monoethanol-C5- carboxybetaine, more preferably comprising being selected from the sweet ammonia of trimethyl It is one kind or two or more in acid, trimethyl serine and hydroxyethyl dimethyl glycine, and then preferably include the sweet ammonia of trimethyl Acid.

With regard to playing excellent keratotic plug removal effect, and for skin assigns the viewpoint of moist feeling, in used combination In object, the content of ingredient (F) is preferably 0.1 mass % or more, more preferably 0.5 mass % or more, and then preferably 1.0 mass More than, in addition, preferably 20 mass % hereinafter, more preferably 15 mass % hereinafter, in turn be preferably 10 mass % or less.Then, In used composition, the content of ingredient (F) is preferably 0.1~20 mass %, more preferably 0.5~15 mass %, into And preferably 1.0~10 mass %.

For dissolving well or dispersing the viewpoint of mentioned component, composition used in the present invention contains (G) water.Institute In the composition used, the content of the water is preferably 10 mass % or more, more preferably 20 mass % or more, and then preferably 30 Quality % or more, and preferably 99.9 mass % hereinafter, more preferably 99.5 mass % hereinafter, in turn be preferably 99 mass % with Under.

For promoting the viewpoint of foaming characteristic, composition used in the present invention can further contain amphoteric surfactant (H).As amphoteric surfactant, can enumerate: amidoamino acid type surfactant, carbobetaine type surfactant, Amide betaine type surfactant, amide sulfo betaine type surfactant, sulfobetaine type surfactant etc..

The content of these amphoteric surfactantes is also possible to be influenced by the dosage form of composition used in the present invention, just mentions High keratotic plug removal effect, for the viewpoint for obtaining excellent foaming characteristic, in used composition, preferably 0.1 mass % More than, more preferably 0.5 mass % or more, and then preferably 1.0 mass % or more, in addition, preferably 15 mass % are hereinafter, more excellent 10 mass % are selected as hereinafter, being in turn preferably 5 mass % or less.Then, in used composition, the content of ingredient (H) Preferably 0.1~15 mass %, more preferably 0.5~10 mass %, and then preferably 1.0~5 mass %.

In the range of the effect of lossless the present application, composition used in the present invention remove containing mentioned component with Outside, the finish such as hydrocarbon ils, ester oil, ether oil, vegetable oil can further be contained；The ingredients such as sodium lactate, urea, pyrrolidone sodium carboxylate (D) and the moisturizer other than ingredient (F)；Ultraviolet absorbing agent；Antioxidant；Fungicide；Extract species；Fragrance；Pigment etc. is logical It is usually used in the ingredient of cosmetics.Furthermore these each preparations are not limited to the purposes as each preparation, visual purpose and work of converting Other purposes, such as antiperspirant is used as fragrance or dual-purpose for other purposes, it is used for example as playing the effect of antiperspirant and fragrance The preparation of fruit.

Composition used in the present invention can be used as cosmetics, quasi drug, drug etc., and there is no particular restriction.Wherein, it just fills For sharing the viewpoint by excellent keratotic plug removal effect, it can be used as keratotic plug removal composition or keratotic plug remover use, it can Suitably it is used as the keratotic plug removal cosmetics for skin for removing keratotic plug.Application section as composition used in the present invention Position, the preferably skin of body, the more preferably skin in addition to scalp such as face, neck, brothers or body, and then be preferably this Pore position on a little skins, and then the pore position on the forehead of preferably face to the skin of nose, can be in the following way It uses: position spread compositions needed for these, by being rinsed with water or being wiped with wipe paper, non-woven fabrics, woven fabric etc. after a certain period of time Material is wiped to wipe the remaining composition of application site off, is preferably rinsed with water.

There is no particular restriction for the dosage form of composition used in the present invention, preferably foam-like, liquid, paste, creams The dosage forms such as shape, with regard to being promoted for the infiltrative viewpoint of keratotic plug, more preferably foam-like, liquid.It is used in the present invention Composition can suitably be used as shampoo, conditioner, hair conditioner etc. for removing the hair cosmetic composition, facial cleanser, face cleaning of keratotic plug Cosmetics, clean body agent, scalp detergent, toner, lotion, creams, beautifying liquid, sunscreen cosmetic, facial mask, massage makeup Product etc. are used to remove the cosmetics for skin of keratotic plug.In these, preferably it is used as facial cleanser, face cleaning cosmetics, clean body agent, head Skin detergent etc. is used to remove the skin cleanser of keratotic plug.

As the use form of composition used in the present invention, can suitably be selected according to application site etc..For example, at this When the dosage form of composition used in inventing is the situations of dosage forms such as liquid, paste, creams shape, composition is applied directly to Application site use.Specifically, more satisfactory for be preferably 0.05~2mL/cm², more preferably 0.1~1mL/cm²'s Amount composition is applied to application site after, application site usually massage 10 seconds~10 minutes, be preferably 15 seconds~5 minutes, More preferably 30 seconds~4 minutes, then the composition for remaining in application site is rinsed with water, or with wipe paper, non-woven fabrics, woven fabric Equal Wiping materials are wiped off, are preferably rinsed with water.

Also, for example it can also be made to be impregnated in nothing when the dosage form of composition used in the present invention is liquid situation The sheet materials such as woven fabric or woven fabric and in the form of plate detergent use.Specifically, more satisfactory to be soaked with composition will contain Plate detergent is directly attached in the state of application site, is usually placed 1 minute~30 minutes, preferably 5 minutes~20 points Clock and then after preferably 10 minutes~15 minutes, removes plate detergent, then rushes the remaining composition of application site with water It washes, or is wiped off with Wiping materials such as wipe paper, non-woven fabrics, woven fabrics, is preferably rinsed with water.

In turn, when the dosage form of composition used in the present invention to be made to the situation of foam-like, such as will be liquid Composition is filled in foam discharge container, spues from container to application site use when use, after discharge, is set as and smears Situation when same usage mode.The dosage form of such foam-like is suitble to be massaged in application site.

Also, composition used in the present invention can also be filled in automiser spray or high pressure cleaner, from nozzle when use Injection uses.At this point, usually to suitable position injection cleaning 10 seconds~5 minutes, preferably 15 seconds~3 minutes, more preferably 30 Second~2 minutes.Then more satisfactory for the composition for remaining in application site to be rinsed with water, or with wipe paper, non-woven fabrics, woven fabric etc. Wiping material is wiped off, is preferably rinsed with water.

Composition used in the present invention can be obtained by following manufacturing method, and the manufacturing method is for example comprising process (I), 60~80 DEG C are heated water in advance；Process (II), to sequentially adding ingredient (A) and view need in process (I) resulting water The other ingredients wanted, are mixed and are stirred；And process (III), process (II) resulting mixture is cooled to 20~35 ℃。

But in the situation there are acid ingredients such as unneutralized fatty acid as used other ingredients, due to Negative electrical charge can be neutralized, therefore worries that ingredient (A) is consumed, and is made under the free state of the ingredient (A) in resulting composition The more set amount of content is reduced, so the more satisfactory process in view of this aspect of above-mentioned operation (II).That is, above-mentioned operation (II) can be set as following process (II) ', and be transferred to above-mentioned operation (III)；The process (II) ' it is the head before adding ingredient (A) First each ingredient other than ingredient (A) is sequentially mixed, being mixed and being stirred dissolves each ingredient, then adds in neutralizer After acid ingredient, adding ingredient (A) is mixed and is stirred and made it dissolve.

Alternatively, neutralizer can also be used not as good as process (II) ', and acid ingredient is directly neutralized by ingredient (A).That is, Above-mentioned operation (II) can be set as following process (II) ", and it is transferred to above-mentioned operation (III)；The process (II) " is in adding ingredient (A) before, each ingredient other than ingredient (A) is sequentially mixed first, is mixed and is stirred and dissolve each ingredient, adding ingredient (A) it after neutralizing acid ingredient, is mixed and is stirred and made it dissolve.In the situation, process (II) " in ingredient (A) additive amount is set as the neutralization institute that the content under the free state of the ingredient in resulting composition (A) adds acid ingredient The amount of the amount of the ingredient (A) needed.

About above embodiment, the method and keratotic plug of the present invention and then the open removal keratotic plug using following composition are gone Except composition.

[1] a kind of method for removing keratotic plug, wherein using containing arginine (A) 0.8 mass % or more and 20 mass % with Under and 25 DEG C at pH value be 8.0 or more and 12.5 compositions below.

[2] such as the method for removing keratotic plug of above-mentioned [1], wherein the content of the ingredient (A) in composition is preferably 1.0 matter % or more, more preferably 2 mass % or more, and then preferably 4 mass % or more, and then preferably 5 mass % or more are measured, and excellent Be selected as 16 mass % hereinafter, more preferably 14 mass % hereinafter, in turn be preferably 12 mass %, and then preferably 10 mass % with Under.

[3] such as the method for removing keratotic plug of above-mentioned [1] or [2], wherein the pH value at 25 DEG C of composition is preferably 8.5 More than, more preferably 8.8 or more, and then preferably 9.0 or more, and then preferably 9.2 or more, and then preferably 9.5 or more, into And preferably 9.8 or more, and then preferably 10.0 or more, and preferably 12.2 hereinafter, more preferably 12.0 hereinafter, in turn preferably For 11.8 hereinafter, being in turn preferably 11.5 hereinafter, being in turn preferably 11.2 hereinafter, being in turn preferably 11.0 or less.

[4] as above-mentioned [1] to any one of [3] removal keratotic plug method, wherein in ingredient (A) with free form There are the content of person and the mass ratio (content of content/ingredient (A) of the ingredient (A) of free state) of the content of ingredient (A) are excellent It is selected as 0.6 or more, more preferably 0.8 or more, and then preferably 0.9 or more, and then preferably 1.0.

[5] such as the method for removing keratotic plug of above-mentioned [1] to any one of [4], wherein composition further contains anion Surfactant (B) preferably contains the anionic surfactant (B1) with carboxylic acid group and/or has as ingredient (B) The anionic surfactant (B2) of sulfonic group or sulfate group.

[6] as above-mentioned [5] removal keratotic plug method, wherein total content of ingredient (B) be preferably 0.01 mass % with On, more preferably 0.02 mass % or more, and then preferably 0.05 mass % or more, and then preferably 0.10 mass % or more, And then preferably 0.3 mass % or more, and then preferably 0.5 mass % or more, and preferably 30 mass % are hereinafter, more preferably 20 mass % hereinafter, in turn be preferably 15 mass %, and then preferably 12 mass % hereinafter, in turn be preferably 8 mass % hereinafter, And then preferably 4 mass % or less.

[7] as above-mentioned [5] or [6] removal keratotic plug method, wherein ingredient (B1) preferably comprising selected from fatty acid or It is one kind or two or more in its salt, ether carboxylic acid or its salt and N- acyl amino hydrochlorate, and ingredient (B2) is preferably comprising being selected from Alkyl benzene sulphonate or its salt, alkyl sulfonic acid or its salt, olefin sulfonic acid or its salt, alkyl sulfonic acid or its salt, acyl group isethionic acid or its Salt, alkyl sulfate or its salt, alkyl ether sulphate or its salt, alkyl sulfosuccinic or its salt, sulfo methyl ester or It is one kind or two or more in its salt, fatty acid alkanol amides sulfuric ester or its salt and monoacylglycerol sulfuric ester or its salt.

[8] such as the method for removing keratotic plug of above-mentioned [5] to any one of [7], wherein in the composition, ingredient (B1) Content is preferably 0.01 mass % or more, more preferably 0.03 mass % or more, more preferably 0.05 mass % or more, Jin Eryou It is selected as 0.08 mass % or more, and then preferably 0.10 mass % or more, and then preferably 0.2 mass % or more, and then preferably For 0.3 mass % or more, and then preferably 0.5 mass % or more, in addition, preferably 5 mass % are hereinafter, more preferably 4 mass % Hereinafter, being in turn preferably 3 mass % hereinafter, being in turn preferably 2 mass % hereinafter, being in turn preferably 1.5 mass % hereinafter, in turn Preferably 1.0 mass % hereinafter, be preferably 0.8 mass % or less in turn.

[9] such as the method for removing keratotic plug of above-mentioned [5] to any one of [8], wherein the content and ingredient of ingredient (A) (B1) mass ratio ((A)/(B1)) of content is preferably 1 or more, and more preferably 2 or more, and then preferably 5 or more, Jin Eryou Be selected as 8 or more, and then preferably 10 or more, and preferably 100 hereinafter, more preferably 70 hereinafter, be preferably in turn 60 hereinafter, into And preferably 50 hereinafter, in turn be preferably 30 hereinafter, in turn be preferably 20 or less.

[10] such as the method for removing keratotic plug of above-mentioned [5] to any one of [9], wherein in the composition, ingredient (B2) Content is preferably 0.01 mass % or more, more preferably 0.02 mass % or more, and then preferably 0.05 or more, and then preferably 0.08 or more, and then preferably 0.10 mass % or more, and then preferably 0.3 mass % or more, and then preferably 0.5 mass % More than, and then preferably 1.0 mass % or more, in addition, preferably 15 mass % are hereinafter, more preferably 10 mass % are hereinafter, in turn Preferably 8 mass %, so preferably 5 mass % hereinafter, in turn be preferably 4 mass % hereinafter, in turn be preferably 3 mass % with Under.

[11] such as the method for removing keratotic plug of above-mentioned [5] to any one of [10], wherein the content and ingredient of ingredient (A) (B2) mass ratio ((A)/(B2)) of content is preferably 0.10 or more, more preferably 0.15 or more, and then preferably 0.20 with On, and then preferably 0.22 or more, and then preferably 0.25 or more, preferably 0.50 or more, in addition, preferably 100 hereinafter, more excellent Be selected as 60 hereinafter, in turn be preferably 50 hereinafter, in turn be preferably 40 hereinafter, in turn be preferably 30 hereinafter, in turn be preferably 20 with Under, so preferably 10 hereinafter, in turn be preferably 5 or less.

[12] such as the method for removing keratotic plug of above-mentioned [1] to any one of [11], wherein in the composition, ingredient (B1) And the content of the anionic surfactant other than (B2) is preferably 0.01 mass % or more, more preferably 0.05 mass % with On, and then preferably 0.1 mass % or more, and preferably 10 mass % hereinafter, more preferably 5 mass % hereinafter, in turn preferably For 1.0 mass % hereinafter, being in turn preferably 0.5 mass % or less.

[13] as above-mentioned [1] to any one of [12] removal keratotic plug method, wherein composition further contain it is non-from Sub- surfactant (C), nonionic surfactant (C1) and/or HLB preferably containing HLB11 or more less than 11 it is non-from Sub- surfactant (C2) is used as ingredient (C).

[14] such as the method for removing keratotic plug of above-mentioned [13], wherein ingredient (C1) is preferably comprising selected from polyglycereol fat Acid esters, cithrol, polyoxyethylene alkyl ether, polyglyceryl fatty acid ester, polyoxyethylene sorbitol acid anhydride rouge It is one kind or two or more in fat acid esters, Crodaret aliphatic ester and alkyl poly glucoside, more preferably wrap Containing selected from cithrol, polyoxyethylene alkyl ether, polyoxyethylene sorbitan carboxylic ester and alkyl polydextrose It is one kind or two or more in glycosides.

[15] such as the method for removing keratotic plug of above-mentioned [13] or [14], wherein ingredient (C2) is preferably selected from polyoxyethylene It is one kind or two or more in alkyl ether and polyglyceryl fatty acid ester.

[16] as above-mentioned [13] to any one of [15] removal keratotic plug method, wherein the content of ingredient (C1) at The mass ratio ((Cl)/(C2)) of the content of point (C2) is preferably 0.1 or more, more preferably 0.6 or more, and then preferably 0.8 with On, and then preferably 1.5 or more, and then preferably 2.5 or more, and preferably 25 hereinafter, more preferably 20 hereinafter, in turn preferably For 16 hereinafter, being in turn preferably 14 hereinafter, being in turn preferably 12 or less.

[17] such as the method for removing keratotic plug of above-mentioned [13] to any one of [16], wherein in the composition, ingredient (C) Content be preferably 0.1 mass % or more, more preferably 0.5 mass % or more, more preferably 0.7 mass % or more, Jin Eryou Be selected as 0.8 mass % or more, and preferably 30 mass % hereinafter, more preferably 25 mass % hereinafter, being in turn preferably 20 matter % is measured hereinafter, being in turn preferably 15 mass % or less.

[18] such as the method for removing keratotic plug of above-mentioned [13] to any one of [17], wherein the content and ingredient of ingredient (A) (C) mass ratio ((A)/(C)) of content is preferably 0.01 or more, and more preferably 0.02 or more, and then preferably 0.03 or more, Also, preferably 25 hereinafter, more preferably 20 hereinafter, in turn be preferably 10 hereinafter, in turn be preferably 8 hereinafter, in turn be preferably 5 with Under, so preferably 3 hereinafter, in turn be preferably 1.0 hereinafter, in turn be preferably 0.8 or less.

[19] such as the method for removing keratotic plug of above-mentioned [1] to any one of [18], wherein composition further contains polynary Alcohol (D), in the composition, the content of the ingredient (D) are preferably 0.5 mass % or more, more preferably 1 mass % or more, are 3 matter Measure % or more, 5 mass % or more, 8 mass % or more, 10 mass % or more, in addition, preferably 40 mass % are hereinafter, more preferably 35 mass % hereinafter, be preferably 30 mass % or less in turn.

[20] such as the method for removing keratotic plug of above-mentioned [19], wherein ingredient (D) is preferably comprising being selected from ethylene glycol, diethyl It is glycol, polyethylene glycol, propylene glycol, dipropylene glycol, polypropylene glycol, isoprene, hexylene glycol, 1,3 butylene glycol, glycerol, two sweet Oil, triglycerin, four glycerol, six glycerol, ten glycerol, trimethyl propanol, antierythrite, pentaerythrite, dipentaerythritol, grape 1 in sugar, mannose, galactolipin, sucrose, fructose, maltose, maltitol, xylitol, inositol, sorbitol anhydride and sorbierite Kind or two or more, more preferably comprising a kind or 2 in dipropylene glycol, 1,3-BDO, glycerol, sorbierite and mannitol Kind.

[21] such as the method for removing keratotic plug of above-mentioned [19] or [20], wherein the content of ingredient (A) contains with ingredient (D's) The mass ratio ((A)/(D)) of amount is preferably 0.01 or more, and more preferably 0.02 or more, and then preferably 0.03 or more, Jin Eryou Be selected as 0.04 or more, and then preferably 0.05 or more, in addition, preferably 6 hereinafter, more preferably 3 hereinafter, in turn be preferably 1.0 with Under, so preferably 0.6 hereinafter, in turn be preferably 0.5 or less.

[22] such as the method for removing keratotic plug of above-mentioned [1] to any one of [21], wherein composition further contains water-soluble Property macromolecule (E), in the composition, the content of the ingredient (E) is preferably 0.01 mass % or more, more preferably 0.05 mass % More than, and then preferably 0.10 mass % or more, and then preferably 0.15 mass % or more, in addition, preferably 3 mass % hereinafter, More preferably 2 mass % hereinafter, be preferably 1 mass % hereinafter, being in turn preferably 0.8 mass % or less in turn.

[23] such as the method for removing keratotic plug of above-mentioned [22], wherein ingredient (E) includes to be selected from carboxy vinyl polymer, third The copolymer of olefin(e) acid-(methyl) alkyl acrylate and addition have a kind or 2 kinds in the cellulose of ethoxy or hydroxypropyl with On.

[24] such as the method for removing keratotic plug of above-mentioned [1] to any one of [23], wherein composition, which further contains, to be selected from One kind or two or more (F) in neutral amino acid, betaine type compound and edetate, and in the composition, it should The content of ingredient (F) is preferably 0.1 mass % or more, more preferably 0.5 mass % or more, and then preferably 1 mass % or more, Also, preferably 20 mass % hereinafter, more preferably 15 mass % hereinafter, in turn be preferably 10 mass % or less.

[25] such as the method for removing keratotic plug of above-mentioned [24], wherein ingredient (F) is preferably comprising being selected from the sweet ammonia of trimethyl It is one kind or two or more in acid, trimethyl serine, hydroxyethyl dimethyl glycine and monoethanol-C5- carboxybetaine, it is more excellent It is selected as including one kind or two or more in trimethylglycine, trimethyl serine and hydroxyethyl dimethyl glycine, into And preferably include trimethylglycine.

[26] such as the method for removing keratotic plug of above-mentioned [1] to any one of [25], wherein composition contains water (G), and should The content of ingredient (G) is preferably 10 mass % or more, more preferably 20 mass % or more, and then preferably 30 mass % or more, Also, preferably 99.9 mass % hereinafter, more preferably 99.5 mass % hereinafter, in turn be preferably 99 mass % or less.

[27] as above-mentioned [1] to any one of [26] removal keratotic plug method, wherein composition be preferably foam-like, The dosage form of liquid, paste or creams shape, more preferably foam-like or liquid dosage form.

[28] a kind of keratotic plug removal composition, wherein containing 0.8 mass % of arginine or more and 20 mass % hereinafter, And the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[29] a kind of composition is for removing the purposes in keratotic plug, wherein the composition contains 0.8 mass % of arginine Above and 20 mass % are hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[30] a kind of clean method of skin, wherein will containing arginine (A) 0.8 mass % or more and 20 mass % with Under and 25 DEG C at pH value be 8.0 or more and 12.5 compositions below be applied to skin, by being rushed after a certain period of time with water It washes, or is wiped off, is preferably rinsed with water.

[31] a kind of manufacturing method such as the composition of above-mentioned [1] to any one of [27] comprising: process (I), 60~80 DEG C are heated water in advance；Process (II), the sequentially adding ingredient (A) and optionally in process (I) resulting water Other ingredients are mixed and are stirred；And process (III), process (II) resulting mixture is cooled to 20~35 DEG C.

[32] a kind of manufacturing method of such as composition of above-mentioned [1] to any one of [27], wherein include acid in composition Property ingredient, and in above-mentioned operation (II), include: process (II1), by each ingredient comprising acid ingredient other than ingredient (A) It sequentially mixes, is mixed and stirred and dissolve each ingredient；Process (II2) then adds neutralizer and neutralizes acid ingredient； And process (II3), then adding ingredient (A), is mixed and is stirred and made it dissolve.

[33] such as manufacturing method of the composition of above-mentioned [32], wherein above-mentioned neutralizer is selected from sodium hydroxide and hydrogen-oxygen Change a kind or 2 kinds in potassium.

[34] a kind of manufacturing method of such as composition of above-mentioned [1] to any one of [27], wherein include acid in composition Property ingredient, and in above-mentioned operation (II), include: process (II1'), by each ingredient comprising acid ingredient other than ingredient (A) It sequentially mixes, is mixed and stirred and dissolve each ingredient；And process (II2'), needed for the neutralization for then adding acid ingredient Ingredient (A) amount more than ingredient (A), mixed and stirred and made it dissolve.

[35] a kind of application method of such as composition of above-mentioned [1] to any one of [27], wherein to preferably body The skin of skin, more preferably face, neck, brothers or body etc. in addition to scalp and then the pore portion preferably on these skins Pore position on position and then the preferably forehead to the skin of nose of face, using the group of such as above-mentioned [1] to any one of [27] Object is closed, by being rinsed with water composition or being wiped off after a certain period of time with Wiping material.

[36] as above-mentioned [35] composition application method, wherein above-mentioned application site massage 10 seconds~10 minutes, Preferably 15 seconds~5 minutes, more preferably 30 seconds~4 minutes, and then preferably 1~3 minute, then to remaining in application site Composition be rinsed with water or wiped off with Wiping material.

[37] a kind of keratotic plug remover, wherein containing 0.8 mass % of arginine or more and 20 mass % hereinafter, and 25 DEG C Under pH value be 8.0 or more and 12.5 or less.

[38] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27] and Any one of [29] composition described in, and the composition contain 1.0 mass % of arginine (A) or more and 16 mass % hereinafter, And the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[39] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38], and the composition contain 2 mass % of arginine (A) or more and 14 mass % with Under, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[40] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29], composition described in any one of [38] and [39], and the composition contains 4 mass % of arginine (A) or more and 12 matter % is measured hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[41] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [40], and the composition contains 5 mass % of arginine (A) or more and 10 matter % is measured hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[42] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [41], and the composition contains arginine (A) and anion surface active Agent (B), in the composition containing ingredient (A) 1.0 mass % or more and 16 mass % hereinafter, and containing ingredient (B) 0.01 matter % or more is measured and 30 mass % hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[43] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [42], and the composition contains arginine (A) and anion surface active Agent (B), in the composition containing ingredient (A) 2 mass % or more and 14 mass % hereinafter, and containing ingredient (B) 0.02 mass % Above and 20 mass % are hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[44] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [43], and the composition contains arginine (A) and anion surface active Agent (B), in the composition containing ingredient (A) 4 mass % or more and 14 mass % hereinafter, and containing ingredient (B) 0.05 mass % Above and 15 mass % are hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[45] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [44], and the composition contains arginine (A) and anion surface active Agent (B), in the composition containing ingredient (A) 5 mass % or more and 10 mass % hereinafter, and containing ingredient (B) 0.10 mass % Above and 12 mass % are hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[46] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [45], and the composition contains arginine (A) and the yin with carboxylic acid group Ionic surface active agent (B1), in the composition containing ingredient (A) 1.0 mass % or more and 16 mass % hereinafter, and containing at Point (B1) 0.01 mass % or more and 5 mass % hereinafter, the content of the content and ingredient (B1) of ingredient (A) mass ratio ((A)/ (B1)) for 1 or more and 100 hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[47] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [46], and the composition contains arginine (A) and the yin with carboxylic acid group Ionic surface active agent (B1) contains ingredient (A) 2 mass % or more and 14 mass % hereinafter, and containing ingredient in the composition (B1) 0.03 mass % or more and 4 mass % hereinafter, the content of the content and ingredient (B1) of ingredient (A) mass ratio ((A)/ (B1)) for 2 or more and 70 hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[48] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [47], and the composition contains arginine (A) and the yin with carboxylic acid group Ionic surface active agent (B1) contains ingredient (A) 4 mass % or more and 12 mass % hereinafter, and containing ingredient in the composition (B1) 0.05 mass % or more and 2 mass % hereinafter, the content of the content and ingredient (B1) of ingredient (A) mass ratio ((A)/ (B1)) for 5 or more and 60 hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[49] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [48], and the composition contains arginine (A) and the yin with carboxylic acid group Ionic surface active agent (B1) contains ingredient (A) 5 mass % or more and 10 mass % hereinafter, and containing ingredient in the composition (B1) 0.1 mass % or more and 0.8 mass % hereinafter, the content of the content and ingredient (B1) of ingredient (A) mass ratio ((A)/ (B1)) for 8 or more and 30 hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[50] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [49], and the composition contains arginine (A) and has sulfonic group or sulphur The anionic surfactant (B2) of perester radical, in the composition containing ingredient (A) 1.0 mass % or more and 16 mass % with Under, and containing ingredient (B2) 0.01 mass % or more and 15 mass % are hereinafter, the content of the content and ingredient (B2) of ingredient (A) Mass ratio ((A)/(B2)) is 0.1 or more and 100 hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[51] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [50], and the composition contains arginine (A) and has sulfonic group or sulphur The anionic surfactant (B2) of perester radical, in the composition containing ingredient (A) 2 mass % or more and 14 mass % hereinafter, And containing ingredient (B2) 0.05 mass % or more and 10 mass % hereinafter, the matter of the content of the content and ingredient (B2) of ingredient (A) It measures than ((A)/(B2)) as 0.15 or more and 60 hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[52] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [51], and the composition contains arginine (A) and has sulfonic group or sulphur The anionic surfactant (B2) of perester radical, in the composition containing ingredient (A) 4 mass % or more and 12 mass % hereinafter, And containing ingredient (B2) 0.08 mass % or more and 8 mass % hereinafter, the quality of the content of the content and ingredient (B2) of ingredient (A) Than ((A)/(B2)) for 0.20 or more and 60 hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[53] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [52], and the composition contains arginine (A) and has sulfonic group or sulphur The anionic surfactant (B2) of perester radical, in the composition containing ingredient (A) 5 mass % or more and 10 mass % hereinafter, And containing ingredient (B2) 0.1 mass % or more and 3 mass % hereinafter, the quality of the content of the content and ingredient (B2) of ingredient (A) Than ((A)/(B2)) for 0.5 or more and 50 hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[54] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [53], and the composition contains arginine (A) and non-ionic surface active Agent (C), in the composition containing ingredient (A) 1.0 mass % or more and 16 mass % hereinafter, and containing ingredient (C) 0.1 mass % Above and 30 mass % are hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[55] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [54], and the composition contains arginine (A) and non-ionic surface active Agent (C), in the composition containing ingredient (A) 2 mass % or more and 14 mass % hereinafter, and containing ingredient (C) 0.5 mass % with Upper and 25 mass % are hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[56] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [55], and the composition contains arginine (A) and non-ionic surface active Agent (C), in the composition containing ingredient (A) 4 mass % or more and 12 mass % hereinafter, and containing ingredient (C) 0.7 mass % with Upper and 20 mass % are hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[57] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [56], and the composition contains arginine (A) and non-ionic surface active Agent (C), in the composition containing ingredient (A) 5 mass % or more and 10 mass % hereinafter, and containing ingredient (C) 0.8 mass % with Upper and 15 mass % are hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[58] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [57], and the composition contains arginine (A) and non-ionic surface active Agent (C), in the composition containing ingredient (A) 1.0 mass % or more and 16 mass % hereinafter, and containing ingredient (C) 0.1 mass % Above and 30 mass % hereinafter, the content of the content and ingredient (C) of ingredient (A) mass ratio ((A)/(C)) be 0.01 or more and 25 hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[59] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [58], and the composition contains arginine (A) and non-ionic surface active Agent (C), in the composition containing ingredient (A) 2 mass % or more and 14 mass % hereinafter, and containing ingredient (C) 0.5 mass % with Upper and 25 mass % are hereinafter, the mass ratio ((A)/(C)) of the content of the content and ingredient (C) of ingredient (A) is 0.02 or more and 10 Hereinafter, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[60] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [59], and the composition contains arginine (A) and non-ionic surface active Agent (C), in the composition containing ingredient (A) 4 mass % or more and 12 mass % hereinafter, and containing ingredient (C) 0.7 mass % with Upper and 20 mass % hereinafter, the content of the content and ingredient (C) of ingredient (A) mass ratio ((A)/(C)) for 0.02 or more and 8 with Under, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[61] a kind of method for removing keratotic plug or purposes for removing keratotic plug, be using such as above-mentioned [1] to [27], [29] and composition described in any one of [38] to [60], and the composition contains arginine (A) and non-ionic surface active Agent (C), in the composition containing ingredient (A) 5 mass % or more and 10 mass % hereinafter, and containing ingredient (C) 0.8 mass % with Upper and 15 mass % hereinafter, the content of the content and ingredient (C) of ingredient (A) mass ratio ((A)/(C)) for 0.03 or more and 5 with Under, and the pH value at 25 DEG C is 8.0 or more and 12.5 or less.

[embodiment]

Hereinafter, the present invention is concretely demonstrated based on embodiment.Furthermore as long as not particularly shown in table, The content of each ingredient indicates quality % (only the sodium cocoyl glutamate of ingredient (A1) is with the record of sour conversion amount).

Prepare the sample of formula shown in table 1~6.Specifically, heat water to 70 DEG C in advance, sequentially add remaining at Divide and be mixed, resulting mixture is cooled to 20 DEG C and can get.Result is shown in table 1~6 together.

Furthermore the measurement of the pH value of resulting sample be at 25 DEG C using pH value meter (hole field production manufactured by, model F- 22) it carries out.

" evaluation of keratotic plug cleaning force "

1. the evaluation of keratotic plug cleaning force when cleaning

" the wonderful nose patch (KAO. Corp. SA's manufacture) of Bioré (Biore) " is used, keratotic plug is removed from nose, is carefully taken out with tweezers The keratotic plug taken out.

By the keratotic plug taken out configuration on glass slide, after being covered with coverslip, sample is added dropwise at the edge of coverslip 0.05mL.Sample enters the gap of glass slide and coverslip by capillarity as a result, can make keratotic plug and sample contacts. Also, utilizing digital microscope (VHX-5000；Keyence company manufacture, 150 times of multiplying power) record keratotic plug and sample contacts feelings Condition comments the permeability of keratotic plug and the disintegration situation of keratotic plug keratotic plug with the sample after sample contacts after 1 minute Valence.It is documented in each evaluation result as " keratotic plug cleaning force (permeability) ", " keratotic plug cleaning force (when cleaning) " in table.Again Person, measurement are carried out at 25 DEG C.

The determinating reference of permeability values is that " sample does not almost infiltrate into keratotic plug " state is set as to 1, will " sample infiltration " center " state in keratotic plug is set as 11, becomes the relative evaluation in 11 stages.Also, what the disintegration of keratotic plug cleaning force was evaluated Determinating reference is that " appearance of keratotic plug is almost unchanged " state is set as 1, " will observe stripping from keratotic plug surface layer to the center portion thereof From, separation (form that the appearance of keratotic plug does not retain initial stage) " state is set as 11, become the relative evaluation in 11 stages.

2. the evaluation of the keratotic plug cleaning force after washing

Make above-mentioned keratotic plug and after 1 minute, makes the side of KimWipes (registered trademark) contact coverslip after sample contacts Edge removes the sample in coverslip.Thereafter, water 0.05mL is added dropwise at the edge of coverslip.Also, being remembered using above-mentioned digital microscope The case where recording the sample after water is added dropwise, by 1 after being contacted to keratotic plug with water according to the determinating reference of the disintegration situation of above-mentioned keratotic plug The disintegration situation of keratotic plug after minute is evaluated.It is documented in evaluation result as " keratotic plug cleaning force (when washing) " in table. Furthermore measurement is carried out at 25 DEG C.

" evaluation of protein coagulation inhibitory effect "

In 35ml glass size bottle, sample 30ml and insoluble protein (zeins (Zein is added Protein)) 0.06g is prepared (trial target) in such a way that insoluble protein becomes 0.2 mass %.Also, preparing to be added Benchmark product made of water replaces sample and adjusted in a manner of making insoluble protein become 0.2 mass %.Thereafter, at 25 DEG C In thermostat, by glass size bottle, sufficiently oscillation stirring (is vibrated with the oscillation amplitude of 15cm, 5 times/3 seconds hunting speeds up and down 20 times), after standing 3 minutes, with the precipitated form of visual confirmation insoluble protein, calculate the precipitation capacities of benchmark product relative to Ratio (precipitation capacity/examination of benchmark product of the precipitation capacity (precipitation capacity is to measure the height of the sediment in glass size bottle) of trial target Test the precipitation capacity of product).This is than bigger, then it represents that inhibits the effect of the agglutination of protein higher.

" skin irritation evaluation "

Each sample 0.1mL is added dropwise in the centre of the palm of each functional panelist by 2 specialty evaluation group members, is massaged 10 seconds Clock.The stick-slip sense of skin is evaluated when according to following determinating references to massage.Evaluation result is formed so that 2 specialty evaluations are small The average value of the evaluation of member indicates.Stick-slip sense is stronger, then it represents that the dissolution degree of cuticula is bigger, and skin irritation is higher.

(determinating reference)

3: feeling strong stick-slip sense

2: feeling slightly stick-slip sense

1: not feeling stick-slip sense

" evaluation of the pliability of skin "

Each sample 1mL is uniformly applied to face by 2 specialty evaluation group members, is massaged 30 seconds with hand, thereafter with certainly Water (water of flushing water is 1000mL/10 seconds, and water temperature is 25~30 DEG C) is rinsed 30 seconds.After flushing, steam is wiped with towel Afterwards, the pliability by skin after twenty minutes is evaluated according to following determinating references.Evaluation result is commented with 2 professions The average value of the evaluation of valence group member indicates.

Furthermore feel that the sample for being irritating to the skin sense does not carry out the softness evaluation test of skin to when smearing.Not into The sample of the row evaluation is expressed as "-" in evaluation result column.

(determinating reference)

4: very soft

3: slightly sense is soft

2: slightly feeling tight

1: very tight

" evaluation of foaming characteristic "

Sample 1mL is added dropwise to by 2 specialty evaluation group members and is bedewed in advance on hand, the centre of the palm of two hands is mutually rubbed It wipes 10 seconds and blisters, foam state at this time is evaluated according to following determinating references.Evaluation result is small with 2 specialty evaluations The average value of the evaluation of group membership indicates.

(determinating reference)

4: foam is more

3: foam is slightly more

2: foam is few

1: almost non-foam

0: not blistering completely

" evaluation of sebum spatter property "

Make 5 mass % of carbon black be dispersed in following 95 mass % of model sebum to be coloured, after melting at 50 DEG C, with diameter The size of 3cm is applied to inner forearm position, and (applying amount of model sebum is about 0.26mg/cm²).After smearing, place 15 minutes After making it dry, swab 1.0mL, after massage 30 seconds, with tap water, (water of flushing water is 1000mL/10 seconds, and water temperature is 25~30 DEG C) it rinses 30 seconds.The residual quantity of model sebum on skin after being rinsed with visual observation, according to following determinating references pair The sebum spatter property is evaluated.

(model sebum)

(determinating reference)

5: not observing the boundary of model sebum spreader portion Yu non-spreader portion completely.

4: On Local Fuzzy observes the boundary of model sebum spreader portion Yu non-spreader portion.

3: observing the entire boundary of model sebum spreader portion Yu non-spreader portion dimly in pole.

2: observing the entire boundary of model sebum spreader portion Yu non-spreader portion dimly.

1: obviously observing the entire boundary of model sebum spreader portion Yu non-spreader portion.

" evaluation of makeup removing "

By foundation cream (SOFINA Primavista (registered trademark) foundation emulsion natural beige (Ochre) 05；KAO. Corp. SA's system Make) inner forearm position, drying 15 minutes are applied to the uniform in size of diameter 3cm.In foundation cream spreader portion swab 1.0mL after massage 30 seconds, is rinsed 30 seconds with tap water (water of flushing water is 1000mL/10 seconds, and water temperature is 25~30 DEG C). Foundation cream is evaluated in the residual quantity of skin according to following determinating references after being rinsed with visual observation.

(determinating reference)

5: not observing the boundary of foundation cream spreader portion Yu non-spreader portion completely.

4: On Local Fuzzy observes the boundary of foundation cream spreader portion Yu non-spreader portion.

3: observing the entire boundary of foundation cream spreader portion Yu non-spreader portion dimly in pole.

2: observing the entire boundary of foundation cream spreader portion Yu non-spreader portion dimly.

1: obviously observing the entire boundary of foundation cream spreader portion Yu non-spreader portion.

" evaluation of moist feeling "

Each sample 1mL is uniformly applied to face by 2 specialty evaluation group members, is massaged 30 seconds with hand, thereafter with certainly Water (water of flushing water is 1000mL/10 seconds, and water temperature is 25~30 DEG C) is rinsed 30 seconds.After flushing, steam is wiped with towel Afterwards, it is evaluated according to moist feeling of following determinating references to skin.Evaluation result is commenting with 2 specialty evaluation group members The average value of valence indicates.

(determinating reference)

4: feeling very high moist feeling

3: feeling high moist feeling

2: slightly feeling moist feeling

1: feeling drying, do not feel moist feeling

According to the result of table 1 it is found that when making keratotic plug with sample contacts 1 minute, common composition of skin cleanser institute POE (2) NaLS of the anionic surfactant used does not almost infiltrate into keratotic plug, even if keratotic plug and POE (2) NaLS contact, the disintegration of keratotic plug also do not have progressed, almost do not show keratotic plug cleaning force.In turn, albumen is acted on The power of matter is stronger, leads to proteolytic.

Also, arginine infiltrates into keratotic plug, in contrast, though disodium hydrogen phosphate, tertiary sodium phosphate, sodium bicarbonate are all weak Alkali, but almost do not infiltrate into keratotic plug.Therefore, even if contacting keratotic plug with disodium hydrogen phosphate, tertiary sodium phosphate or sodium bicarbonate, angle The disintegration of bolt does not also have progressed, does not almost show keratotic plug cleaning force.

In turn, when making keratotic plug contact 1 minute with water, the keratotic plug contacted with arginine more swelling is observed, keratotic plug The phenomenon that disintegration is further in progress.On the other hand, even if making the keratotic plug contacted with disodium hydrogen phosphate, tertiary sodium phosphate or sodium bicarbonate It is contacted with water, does not also observe that the swelling of keratotic plug, the disintegration of keratotic plug do not have progressed.

Therefore, in order to which the disintegration of keratotic plug when making washing is in progress, keratotic plug is removed from pore, keratotic plug when preferably cleaning Cleaning force is scored at 3 or more, and the disintegration of keratotic plug becomes larger when keratotic plug cleaning force when cleaning is washed if being scored at 5 or more, can Keratotic plug is more quickly removed, therefore more preferably.

[table 5]

* 1:Emal 227 (KAO. Corp. SA's manufacture)

* 2: lauric acid/myristic acid/palmitinic acid/stearic acid=1/3/1/1 (mass parts)

* 3:KAO AKIPO RLM-45CA (KAO. Corp. SA's manufacture)

* 4: Japanese Patent Laid-Open 2015-28123, the inner olefin sulfonic acid salt composite of Production Example 7

* 5:EMULGEN 121 (KAO. Corp. SA's manufacture)

* 6:EMANON 1112 (KAO. Corp. SA's manufacture)

* 7:MYDOL 10 (KAO. Corp. SA's manufacture)

* 8:Cosmol 41V (manufacture of Nisshin OilliO Group company)

Hereinafter, recording Formulation Example of the invention.Generate effect identical with embodiment.

[Formulation Example 1 (Cleansing Foam)]

(Cleansing Foam)

[Formulation Example 2 (Cleansing Foam)]

[Formulation Example 3 (Cleansing Foam)]

[Formulation Example 4 (clean body agent)]

* 9:AKYPO LM 26C (KAO. Corp. SA's manufacture)

* 10:Amphitol 20HD (KAO. Corp. SA's manufacture)

* 11:HEC Daicel SE850 (manufacture of Daicel FineChem company)

* 12:Carbopol ETD2020 polymer (manufacture of Lubrizol Advanced Materials company)

* 13:Carbopol Ultrez 21polymer (manufacture of Lubrizol Advanced Materials company).

Claims (14)

1. a kind of method for removing keratotic plug, wherein

Using the pH value containing arginine (A) 0.8 mass % or more and at 20 mass % or less and 25 DEG C be 8.0 or more and 12.5 composition below.

2. the method for removal keratotic plug as described in claim 1, wherein

Composition further contains anionic surfactant (B).

3. the method for removal keratotic plug as claimed in claim 2, wherein

Ingredient (B) includes the anionic surfactant (B1) with carboxylic acid group, and/or the yin with sulfonic group or sulfate group Ionic surface active agent (B2).

4. the method for removal keratotic plug as claimed in claim 2 or claim 3, wherein

The content of ingredient (B) in composition is 0.01 mass % or more and 30 mass % or less.

5. the method for removal keratotic plug as described in any one of claims 1 to 4, wherein

Ingredient (B) includes the anionic surfactant (B1) with carboxylic acid group, and,

Mass ratio (A)/(B1) of the content of the content and ingredient (B1) of ingredient (A) is 1 or more and 100 or less.

6. such as the method for removal keratotic plug according to any one of claims 1 to 5, wherein

Ingredient (B) includes the anionic surfactant (B2) with sulfonic group or sulfate group, and,

Mass ratio (A)/(B2) of the content of the content and ingredient (B2) of ingredient (A) is 0.1 or more and 100 or less.

7. such as the method for removal keratotic plug according to any one of claims 1 to 6, wherein

Composition further contains nonionic surfactant (C).

8. the method for removal keratotic plug as claimed in claim 7, wherein

The content of ingredient (C) in composition is 0.1 mass % or more and 30 mass % or less.

9. such as the method for removal keratotic plug according to any one of claims 1 to 8, wherein

Composition further contains polyalcohol (D).

10. the method for removal keratotic plug as claimed in claim 9, wherein

The content of ingredient (D) in composition is 0.5 mass % or more and 30 mass % or less.

11. such as the method for removal keratotic plug according to any one of claims 1 to 10, wherein

Composition further contains 10 mass % of water or more and 99.9 mass % or less.

12. a kind of clean method of skin, wherein

It will be 8.0 or more and 12.5 containing the pH value at arginine (A) 0.8 mass % or more and 20 mass % or less and 25 DEG C Composition below is applied to skin, is after some period of time rinsed with water composition or is wiped off with Wiping material.

13. a kind of keratotic plug removal composition, wherein

Containing 0.8 mass % of arginine (A) or more and 20 mass % hereinafter, and pH value at 25 DEG C be 8.0 or more and 12.5 with Under.

14. a kind of keratotic plug remover, wherein

Containing 0.8 mass % of arginine (A) or more and 20 mass % hereinafter, and pH value at 25 DEG C be 8.0 or more and 12.5 with Under.