CN110404595A - Kit for identifying skin diseases - Google Patents

Kit for identifying skin diseases Download PDF

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Publication number
CN110404595A
CN110404595A CN201910699189.0A CN201910699189A CN110404595A CN 110404595 A CN110404595 A CN 110404595A CN 201910699189 A CN201910699189 A CN 201910699189A CN 110404595 A CN110404595 A CN 110404595A
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CN
China
Prior art keywords
layer
handle portion
ontology
kit
buffer layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910699189.0A
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Chinese (zh)
Inventor
陈晋广
范华宇
王渟
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Taizhou Central Hospital Taizhou University Hospital
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Taizhou Central Hospital Taizhou University Hospital
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Publication date
Application filed by Taizhou Central Hospital Taizhou University Hospital filed Critical Taizhou Central Hospital Taizhou University Hospital
Priority to CN201910699189.0A priority Critical patent/CN110404595A/en
Publication of CN110404595A publication Critical patent/CN110404595A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B2010/0216Sampling brushes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention provides a kit for identifying skin diseases, which comprises a box body and a raw material arranged in the box body and used for preparing hematoxylin, and is characterized in that: the extraction rod comprises an extraction part and a handle part; the extraction part comprises an extraction layer used for being in contact with a human body and a buffer layer arranged below the extraction layer and used for buffering the contact of the extraction layer and the human body. The kit has a simple structure, and all reagents can be placed in the kit and can be used through simple configuration.

Description

A kind of kit identified for skin disease
Technical field
The present invention relates to medical kit field more particularly to a kind of kits identified for skin disease.
Background technique
Currently, skin disease is particularly important as current high-incidence illness type, to its discovery in time with treatment.Skin Disease be skin (including hair and first) by the influence of internal and external factor after, form, structure and function change, generate disease Reason process, and correspondingly generate a kind of disease of various clinical manifestations.Dermopathic disease incidence is higher, and clinical symptoms compare more Gently, often not unhealthful, but a small number of state of an illness even can be with threat to life compared with severe one.The diagnosis of current common skin diseases still excessively according to Rely in medical practitioner, this has following defects that on the one hand since many dermopathic shapes are similar, symptom is similar, patient is difficult to It is effectively distinguished by autodiagnosis, such as common mole and melanoma, if melanoma is accidentally considered common mole not by patient Aggravate view, then it may delay treatment.And on the other hand, common skin diseases diagnostic work brings a large amount of repeated labor to doctor It is dynamic, increase the anxiety of medical resource.
It in hospital by way of checking and then being diagnosed, needs to spend people's a large amount of quality time, and usually In the case of, most of skin disease is the skin disease constantly aggravated with the time, if carried out in time without before going to the hospital Preliminary diagnoses and treatment be easy to cause the delay of the state of an illness, influences the therapy rehabilitation in later period.
Skin disease is located at body surface, and it is convenient to examine, but histopathology materials need to cut or drill through skin holostrome, make patient New wound is generated, the rehabilitation of patient is unfavorable for, and non-invasive laboratory diagnosis is easier to be accepted by patients.
Summary of the invention
The invention proposes a kind of kits identified for skin disease, and the apparatus structure is simple, changes previous examine Disconnected mode, is examined using non-invasive, promotes Patient Experience.
The present invention solves above-mentioned technical problem and is adopted the technical scheme that: a kind of kit identified for skin disease, Including box body, box is arranged in, and intracorporal for configuring, haematoxylin raw material, that box is arranged in is intracorporal for extracting skin histology Extraction rod, its technical solution is that: the extraction rod includes extraction unit and handle portion;Wherein, the extraction unit includes using In with the extract layer of human contact and be arranged in below extract layer for buffering extract layer and the buffer layer of human contact.
Have the beneficial effect that reagent cartridge configuration of the present invention is simple brought by the present invention, each reagent can be placed It can be used in kit, and through simply configuration.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with It obtains other drawings based on these drawings.
Fig. 1 is structural schematic diagram of the invention.
Fig. 2 is a kind of embodiment of extraction rod.
Fig. 3 is another embodiment of extraction rod.
Wherein, 1. box body;2. extraction rod;201. extraction unit;202. handle portion;2011. extract layer;2012. buffer layer; 20121. bottom;20122. column-shaped projection;20111. articulamentum;20112. nylon contact layer;101. ontology;1A. partition;102. Lid;11A. tubular region.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, those of ordinary skill in the art are obtained every other under that premise of not paying creative labor Embodiment shall fall within the protection scope of the present invention.
Such as Fig. 1, a kind of kit identified for skin disease including box body 1, is arranged in box body 1 and is used for The extraction rod 2 for being used to extract skin histology for configuring haematoxylin raw material, being arranged in box body 1, its technical solution is that: it is described Extraction rod 2 include extraction unit 201 and handle portion 202;Wherein, the extraction unit 201 includes for mentioning with human contact The buffer layer 2012 for being used to buffer extract layer 2011 Yu human contact for taking layer 2011 and being arranged in below extract layer 2011.
Wherein, fash area surface layer cast-off cells sampling method is: it is contacted by extract layer 2011 with affected skin, it is horizontal To multiple moving handle portion 202, drives extract layer 2011 to move repeatedly in affected part, extract layer 2011 is made to be stained with enough samples, Due to the presence of buffer layer 2012, it can prevent skin from secondary injury occurs with the skin in effective protection affected part;Then, it will extract Layer 2011 is contacted with glass slide, sample cell is placed on glass slide, then covered, and preparation is completed.
Haematoxylin raw material of the present invention is Potassium aluminum sulfate dodecahydrate powder and haematoxylin pulvis, absolute alcohol, iodine Sour sodium powder end, glacial acetic acid liquid and glycerol liquids.The haematoxylin dye liquor includes 35 grams of Potassium aluminum sulfate dodecahydrate, haematoxylin powder Agent 4g, absolute alcohol 33ml, 0.08 gram of sodium iodate, glacial acetic acid 32ml and glycerol 32ml.
The preparation method of the haematoxylin dye liquor is:
1. 5000ml distilled water is added in Potassium aluminum sulfate dodecahydrate, heating dissolves Potassium aluminum sulfate dodecahydrate sufficiently, cooling Aluminum potassium sulfate solution is obtained to room temperature;
2. haematoxylin pulvis, absolute alcohol heating are taken respectively, it is molten with above-mentioned aluminum aluminum sulfate after dissolving haematoxylin pulvis Liquid mixes, and sodium iodate stirring is then added and is allowed to dissolve within 2 minutes, is stored at room temperature 15 hours;
3. skimming surface film oxide, glacial acetic acid, glycerol is successively added, stirring evenly can be used.
Box body 1 in kit as described herein is made of columnar ontology 101 and lid 102;Specification setting Between ontology 101 and lid 102;Wherein, multiple partition 1A are axially provided in ontology 101;By the spatial axes in ontology 101 To being divided into multiple regions;It is connect by hinge with lid 102 on the axial end face of ontology 101;On lid 102 and ontology 101 It is additionally provided with the lock for opening and closing.Multiple regions in ontology 101 are used to place the material of reagent preparation, including bottled ten Sulfate dihydrate aluminium potassium powder and haematoxylin pulvis, bottled 25~32ml of absolute alcohol, bottled sodium iodate powder, bottled ice Acetic acid liquid and glycerol liquids.Above-mentioned multiple bottle bodies are both placed in the region being partitioned by partition 1A.In order to increase transport When reliability, can in placing bottle body inside increase the foams of buffering;The technology is common in packaging field, does not do herein Excessively repeat.
Wherein, one end of multiple partition 1A is connected, and the other end is radial to be arranged in ontology 101;Multiple partition 1A simultaneously Connected region is provided with tubular region 11A;The diameter of tubular region 11A is slightly larger than the diameter of extraction rod 2, and inside is arranged There is the buffer structure of foam or cotton.
Under the premise of considering cost, such as Fig. 2, extraction rod 2 can be wrapped in handle portion 202 by the buffer layer 2012 of medical cotton One end blend compounds it is viscous;Gluing is utilized after the extract layer 2011 of the outside winding medical non-woven fabrics of buffer layer 2012, makes buffer layer 2012, extract layer 2011 and handle portion 202 become an entirety;Handle portion 202 is PVC stick.Delay note that glue only serves stickup The effect of layer 2012, extract layer 2011 and handle portion 202 is rushed, affected part tissue will not be pasted.
Medical non-woven fabrics is used to pick affected part tissue or cell with skin contact;Then the doctor of affected part tissue or cell is speckled with It is contacted with non-woven fabrics with glass slide or manually flicking handle portion 202 falls the tissue being stained on non-woven fabrics on glass slide.
Discovery in use, although affected part tissue can be stained with using medical non-woven fabrics, when shifting on glass slide It is highly difficult, it is easy to appear the case where can not shifting.
To solve the above-mentioned problems, it such as Fig. 3, is buffered in one end for being contacted with affected part of handle portion 202 by gluing Layer 2012;The buffer layer 2012 is by the bottom 20121 with 202 adhesion of handle portion and the multiple cylindricalitys being arranged on bottom 20121 Protrusion 20122 forms;Extract layer 2011 is made of articulamentum 20111 and nylon contact layer 20112;Wherein, multiple column-shaped projections 20122 gluing plays buffer function simultaneously with articulamentum 20111;The height of column-shaped projection 20122 is 0.8~1.2mm;Nylon connects The protrusion of uneven distribution is provided in contact layer 20112;Change the preferred hemispherical of protrusion, it can be with effective protection skin not by secondary wound Evil.Wherein, articulamentum 20111 is PVC;The material of bottom 20121 and column-shaped projection 20122 is silica gel.
When in use, handle portion 202 drives nylon contact layer 20112 to contact with affected part, nylon contact layer 20112 and skin After contact, the tissue in affected part is stained on its surface.Then, nylon contact layer 20112 is contacted with glass slide, and moved back and forth, Then, electrostatic is generated on glass slide, is stained with the tissue being stained on nylon contact layer 20112 on glass slide by electrostatic interaction, Then coverslip is covered, detection sample is made.
Its principle is: the polarity of electrostatic, the sequence that various substances are successively lined up are generated when contacting with each other according to two kinds of substances Column.According to this sequence, when both front and back substance contacts, the former is positively charged, and the latter is negatively charged.The work function of various substances can be used Different or substance polar group difference is explained.Situations such as charging polarity is also related with the factors such as temperature, impurity.
(+) glass, organic glass, nylon, wool, silk, celluloid, cotton goods, paper, metal, black rubber, terylene, dimension Nylon, polystyrene, polypropylene, polyethylene, polyvinyl chloride, polytetrafluoroethylene (PTFE) (-) are to the object of contact electrification, it should select as far as possible Position is adjoining in point sequence, can reduce the generation of electrostatic charge;Two kinds of objects in electrostatic relatively far apart Be in contact generation contact electromotive force it is also larger.Glass can generate smaller electrostatic together with nylon as a result,.
The foregoing is merely the preferred embodiment of invention, oneself, is not intended to limit the invention, all in spirit of the invention With any modifications, equivalent replacements, and improvements made within principle etc., should all be included in the protection scope of the present invention.

Claims (5)

1. a kind of kit identified for skin disease configures haematoxylin including box body (1), setting being used in box body (1) Raw material and be arranged in box body (1) for extracting the extraction rod (2) of skin histology;It is characterized by: the extraction rod It (2) include extraction unit (201) and handle portion (202);Wherein, the extraction unit (201) includes for mentioning with human contact The buffer layer for being used to buffer extract layer (2011) and human contact for taking layer (2011) and being arranged below extract layer (2011) (2012)。
2. a kind of kit identified for skin disease according to claim 1, it is characterised in that: the buffer layer (2012) it is wrapped in one end of handle portion (202);The outside of buffer layer (2012) winds extract layer (2011);Extract layer (2011) For medical non-woven fabrics;Buffer layer (2012) is medical cotton layer;Handle portion (202) is PVC stick.
3. a kind of kit identified for skin disease according to claim 1, it is characterised in that: handle portion (202) One end is provided with buffer layer (2012);The buffer layer (2012) includes the bottom (20121) connecting with handle portion (202) and setting Multiple column-shaped projections (20122) on bottom (20121);Extract layer (2011) includes articulamentum (20111) and nylon contact Layer (20112);Wherein, multiple column-shaped projections (20122) connect simultaneously with articulamentum (20111);On nylon contact layer (20112) It is provided with the protrusion of uneven distribution.
4. a kind of kit identified for skin disease according to claim 1, it is characterised in that: box body (1) includes this Body (101) and lid (102);Wherein, multiple partitions (1A) is provided in ontology (101);Space in ontology (101) is axial It is divided into multiple regions;It is connect by hinge with lid (102) on the axial end face of ontology (101);Lid (102) and ontology (101) lock for opening and closing is additionally provided on.
5. a kind of kit identified for skin disease according to claim 4, it is characterised in that: multiple partitions (1A) One end is connected the radial setting of the other end in ontology (101);Multiple partitions (1A) region connected simultaneously is provided with tubular Region (11A).
CN201910699189.0A 2019-07-31 2019-07-31 Kit for identifying skin diseases Pending CN110404595A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910699189.0A CN110404595A (en) 2019-07-31 2019-07-31 Kit for identifying skin diseases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910699189.0A CN110404595A (en) 2019-07-31 2019-07-31 Kit for identifying skin diseases

Publications (1)

Publication Number Publication Date
CN110404595A true CN110404595A (en) 2019-11-05

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CN201910699189.0A Pending CN110404595A (en) 2019-07-31 2019-07-31 Kit for identifying skin diseases

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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201022902Y (en) * 2007-04-21 2008-02-20 韩胜乐 Medicinal bar for treating skin disease
WO2009018607A1 (en) * 2007-08-03 2009-02-12 Polartechnics Limited Device and method for biological sampling
CN101983036A (en) * 2008-02-15 2011-03-02 3M创新有限公司 Sample acquisition device
CN202761330U (en) * 2012-06-08 2013-03-06 龙笑 Sample sending cup for fixed-point pathologic examination in surgery
CN202875488U (en) * 2012-10-15 2013-04-17 三门县永力模具塑料厂(普通合伙) Rotation type needle box
US20150119785A1 (en) * 2013-10-30 2015-04-30 Terata Ann Kanu Ear wax cleaning device
JP2015090330A (en) * 2013-11-07 2015-05-11 勝恒 佐藤 Sponge swab specimen sampling tool
CN206063180U (en) * 2016-07-17 2017-04-05 佛山市大臻医学检验所有限公司 Separate type sampling swab for oral cavity
CN106932329A (en) * 2017-04-28 2017-07-07 上海市浦东新区周浦医院 A kind of skin disease antidiastole detects box

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201022902Y (en) * 2007-04-21 2008-02-20 韩胜乐 Medicinal bar for treating skin disease
WO2009018607A1 (en) * 2007-08-03 2009-02-12 Polartechnics Limited Device and method for biological sampling
CN101983036A (en) * 2008-02-15 2011-03-02 3M创新有限公司 Sample acquisition device
CN202761330U (en) * 2012-06-08 2013-03-06 龙笑 Sample sending cup for fixed-point pathologic examination in surgery
CN202875488U (en) * 2012-10-15 2013-04-17 三门县永力模具塑料厂(普通合伙) Rotation type needle box
US20150119785A1 (en) * 2013-10-30 2015-04-30 Terata Ann Kanu Ear wax cleaning device
JP2015090330A (en) * 2013-11-07 2015-05-11 勝恒 佐藤 Sponge swab specimen sampling tool
CN206063180U (en) * 2016-07-17 2017-04-05 佛山市大臻医学检验所有限公司 Separate type sampling swab for oral cavity
CN106932329A (en) * 2017-04-28 2017-07-07 上海市浦东新区周浦医院 A kind of skin disease antidiastole detects box

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Application publication date: 20191105