CN110369409B - A wash solenoid valve composite set for DNA synthesizer - Google Patents
A wash solenoid valve composite set for DNA synthesizer Download PDFInfo
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- CN110369409B CN110369409B CN201910776412.7A CN201910776412A CN110369409B CN 110369409 B CN110369409 B CN 110369409B CN 201910776412 A CN201910776412 A CN 201910776412A CN 110369409 B CN110369409 B CN 110369409B
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- cleaning
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- electromagnetic valve
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
- B08B9/02—Cleaning pipes or tubes or systems of pipes or tubes
- B08B9/027—Cleaning the internal surfaces; Removal of blockages
- B08B9/032—Cleaning the internal surfaces; Removal of blockages by the mechanical action of a moving fluid, e.g. by flushing
Abstract
The invention relates to a cleaning electromagnetic valve combination device for a DNA synthesizer, which comprises an electromagnetic valve seat, a cleaning electromagnetic valve and a plurality of first electromagnetic valves, wherein a main channel, a cleaning liquid inlet, a gas inlet, a plurality of medicament liquid inlets and a plurality of liquid outlets are formed in the electromagnetic valve seat, the positions of the plurality of first electromagnetic valves, the plurality of medicament liquid inlets and the plurality of liquid outlets are in one-to-one correspondence, the medicament liquid inlets and the liquid outlets are connected with the main channel through the corresponding first electromagnetic valves, and the cleaning liquid inlets and the gas inlet are connected with the main channel through the cleaning electromagnetic valves. Solves the problems of complex operation, multiple operation times and manual waste caused by cleaning the pipeline of the dispensing device and the dispensing needle head by cleaning liquid and inert protective gas.
Description
Technical Field
The invention relates to the technical field of biology, in particular to a cleaning electromagnetic valve combination device for a DNA synthesizer.
Background
At present, the artificially synthesized DNA is the only way for the known directional modification of gene sequences, and is widely applied to a plurality of fields such as protein modification, life science and the like, such as nucleic acid medicine, enzyme engineering, gene detection, gene therapy and the like. The DNA synthesizer needs the steps of deprotection, activation linking, capping, oxidization and the like in the synthesis process, different reagents are required to be injected into a synthesis column in the synthesis process, and the modern industry needs to realize large-scale mass production, so that the high-throughput DNA synthesizer is required, and a special dispensing device is also required. At present, at least 4 monomer reagents and 6 auxiliary reagents are usually needed for the foreign and domestic synthesizers, if the high-throughput synthesizers need large-scale mass production and shorten the synthesis time, the number of dispensing nozzles of the high-throughput synthesizers in the domestic and foreign markets is as high as 80 or 160, each reagent needs to be split into 8 or 16 outlets for dispensing through an electromagnetic valve, for the high-throughput DNA synthesizers, the volume of the dispensed reagent is required to be small, and the needle caliber of a liquid outlet is necessarily required to be extremely small to dispense the accurate small-volume reagent, however, the individual reagents in a pipeline are easy to crystallize when not flowing, and once the pipeline is blocked, the pipeline can only be manually dredged, the needle caliber of the liquid outlet is small, and great difficulty is brought to manual dredging. Thus, the current cleaning of the dispensing device tubing and the dispensing needle has the following problems: 1. in order to avoid blockage of the liquid outlet needle head and the pipeline, each channel is required to be cleaned once by cleaning liquid after each synthesis is finished, the operation is complex, the operation times are high, and the labor waste is caused; 2. the cleaning mode of the DNA separate injection device, which is frequently used for cleaning the cleaning liquid and the inert protective gas, is frequently switched, so that the labor waste is caused. Therefore, a new electromagnetic valve or electromagnetic combination mode is urgently needed to realize the automatic cleaning switching of electric control.
Disclosure of Invention
The invention aims to solve the technical problems of complex cleaning operation, multiple operation times and manual waste of a dispensing device pipeline and a dispensing needle head by providing a cleaning electromagnetic valve combined device for a DNA synthesizer.
The technical scheme for solving the technical problems is as follows: a wash solenoid valve composite set for DNA synthesizer, includes solenoid valve seat 1, washs solenoid valve 2 and a plurality of first solenoid valve 3, main passageway 4, washing liquid inlet 5, gas inlet 6, a plurality of medicament inlet 7 and a plurality of liquid outlet 8 have been seted up on the solenoid valve seat 1, a plurality of first solenoid valve 3, a plurality of medicament inlet 7 and a plurality of the position one-to-one of liquid outlet 8, medicament inlet 7 with liquid outlet 8 is through corresponding first solenoid valve 3 with main passageway 4 is connected, washing liquid inlet 5 with gas inlet 6 is through washs solenoid valve 2 with main passageway 4 is connected.
Further, a first small hole group and a plurality of rows of second small hole groups are arranged on the electromagnetic valve seat 1, the first small hole group and the plurality of rows of second small hole groups are connected through the main channel 4, the position of the first small hole group corresponds to that of the cleaning electromagnetic valve 2, the first small hole group corresponds to that of the cleaning liquid inlet 5 and the gas inlet 6, the positions of the plurality of rows of second small hole groups correspond to the plurality of first electromagnetic valves 3 respectively, and the plurality of rows of second small hole groups are connected with the corresponding plurality of medicament liquid inlets 7 and the plurality of liquid outlets 8.
Further, the first small hole group comprises a 1 st small hole 9, a 1 st small hole 10, a 1 st small hole 3 and a 1 st small hole 11, the 1 st small hole 9 is communicated with the gas inlet 6, the 1 st small hole 10 is communicated with the main channel 4, and the 1 st small hole 11 is communicated with the cleaning liquid inlet 5.
Further, the second hole group includes a plurality of 2-1 holes 12, a plurality of 2-2 holes 13 and a plurality of 2-3 holes 14, the plurality of 2-1 holes 12 are all communicated with the main channel 4, the plurality of 2-2 holes 13 are respectively communicated with the corresponding plurality of liquid outlets 8, and the plurality of 2-3 holes 14 are respectively communicated with the corresponding plurality of medicine liquid inlets 7.
Further, when the cleaning electromagnetic valve 2 is powered off, the 1 st to 3 rd small holes 11 are communicated with the 1 st to 2 nd small holes 10, and when the cleaning electromagnetic valve 2 is powered on, the 1 st to 1 st small holes 9 are communicated with the 1 st to 2 nd small holes 10.
Further, when the first electromagnetic valves 3 are powered off, the 2-3 small holes 14 are communicated with the 2-2 small holes 13, and when the first electromagnetic valves 3 are powered on, the 2-1 small holes 12 are communicated with the 2-2 small holes 13.
Further, the plurality of first electromagnetic valves 3 and the cleaning electromagnetic valve 2 are two-position three-way electromagnetic valves.
Further, the cleaning solution inlet 5 and the gas inlet 6 are correspondingly disposed at two sides of the electromagnetic valve seat 1, and are distributed on a vertical axis.
Further, the plurality of medicine liquid inlets 7 and the plurality of liquid outlets 8 are correspondingly arranged at two sides of the electromagnetic valve seat 1 and distributed on a vertical line.
The invention provides a cleaning electromagnetic valve combination device for a DNA synthesizer, which comprises an electromagnetic valve seat 1, a cleaning electromagnetic valve 2 and a plurality of first electromagnetic valves 3, wherein a main channel 4, a cleaning liquid inlet 5, a gas inlet 6, a plurality of medicament liquid inlets 7 and a plurality of liquid outlets 8 are formed in the electromagnetic valve seat 1, the positions of the plurality of first electromagnetic valves 3, the plurality of medicament liquid inlets 7 and the plurality of liquid outlets 8 are in one-to-one correspondence, the medicament liquid inlets 7 and the liquid outlets 8 are connected with the main channel 4 through the corresponding first electromagnetic valves 3, and the cleaning liquid inlets 5 and the gas inlets 6 are connected with the main channel 4 through the cleaning electromagnetic valves 2. Like this, a plurality of first solenoid valves 3, a plurality of medicament inlet 7 and a plurality of liquid outlet 8 quantity and position one-to-one, washing liquid inlet 5 and gas air inlet 6 all are connected with main channel 4 through wasing solenoid valve 2, a plurality of medicament inlet 7 and a plurality of liquid outlet 8 all are linked together with main channel 4 through a plurality of corresponding first solenoid valves 3, can set up a plurality of medicament inlet 7, liquid outlet 8 and first solenoid valve 3 of corresponding number according to the kind of monomer reagent and the kind of auxiliary reagent in the DNA synthesis during the use, every first solenoid valve 3 can control the intercommunication of corresponding medicament inlet 7 and liquid outlet 8 and main channel 4. When in normal use, after a certain reagent enters from the reagent liquid inlet 7, the corresponding first electromagnetic valve 3 is switched by a valve, so that the reagent directly flows out from the corresponding liquid outlet 8; when a pipeline and a needle corresponding to a certain reagent are required to be cleaned by using cleaning liquid, after the cleaning liquid enters from a cleaning liquid inlet 5, a cleaning electromagnetic valve 2 is switched through a valve, so that the cleaning liquid directly enters a main channel 4, at the moment, a first electromagnetic valve 3 corresponding to the reagent is switched through the valve, so that a liquid outlet 8 corresponding to the reagent is communicated with the main channel 4, and in this way, the cleaning liquid enters the liquid outlet 8 corresponding to the reagent after flowing through the main channel 4, and further, the cleaning of the corresponding pipeline and the needle of the reagent dispensing device is realized; when the pipeline and the needle corresponding to a certain reagent need to be cleaned by inert protective gas, after the inert protective gas enters from the gas inlet 6, the cleaning electromagnetic valve 2 is switched through a valve, so that the inert protective gas directly enters into the main channel 4, at the moment, the first electromagnetic valve 3 corresponding to the reagent is switched through a valve, so that the liquid outlet 8 corresponding to the reagent is communicated with the main channel 4, and thus, the inert protective gas enters the liquid outlet 8 corresponding to the reagent after flowing through the main channel 4, and further, the cleaning of the corresponding pipeline and the needle of the reagent dispensing device is realized. Each reagent corresponds to the respective reagent liquid inlet 7, liquid outlet 8 and first solenoid valve 3, so that cleaning of the pipeline and needle of each reagent dispensing device by the cleaning liquid and the inert shielding gas can be realized by controlling the switching of the valves of the cleaning solenoid valve 2 and the corresponding first solenoid valve 3.
Drawings
FIG. 1 is a schematic diagram showing the distribution of the pipeline of a combined device for cleaning electromagnetic valves for a DNA synthesizer;
FIG. 2 is a schematic view of a combination of solenoid purge valves for a DNA synthesizer according to the present invention;
FIG. 3 is a schematic view showing a whole assembly of a cleaning solenoid valve for a DNA synthesizer according to the present invention;
in the drawings, the list of components represented by the various numbers is as follows:
1. the electromagnetic valve seat, 2, the cleaning electromagnetic valve, 3, the first electromagnetic valve, 4, the main channel, 5, the cleaning liquid inlet, 6, the gas inlet, 7, the medicament inlet, 8, the liquid outlet, 9, the 1 st-1 aperture, 10, the 1 st-2 aperture, 11, the 1 st-3 aperture, 12, the 2 nd-1 aperture, 13, the 2 nd-2 aperture, 14, the 2 nd-3 aperture.
Detailed Description
The principles and features of the present invention are described below with reference to the drawings, the examples are illustrated for the purpose of illustrating the invention and are not to be construed as limiting the scope of the invention.
In the description of the present invention, it should be understood that the terms "upper," "lower," "center," "inner," "outer," "top," "bottom," and the like indicate or are based on the orientation or positional relationship shown in the drawings, merely to facilitate description of the invention and to simplify the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the invention.
In the description of the present invention, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.
As shown in fig. 1-3, the invention provides a cleaning electromagnetic valve assembly device for a DNA synthesizer, which comprises an electromagnetic valve seat 1, a cleaning electromagnetic valve 2 and a plurality of first electromagnetic valves 3, wherein a main channel 4, a cleaning fluid inlet 5, a gas inlet 6, a plurality of medicament liquid inlets 7 and a plurality of liquid outlets 8 are arranged on the electromagnetic valve seat 1, the positions of the plurality of first electromagnetic valves 3, the plurality of medicament liquid inlets 7 and the plurality of liquid outlets 8 are in one-to-one correspondence, the medicament liquid inlets 7 and the liquid outlets 8 are connected with the main channel 4 through the corresponding first electromagnetic valves 3, and the cleaning fluid inlet 5 and the gas inlet 6 are connected with the main channel 4 through the cleaning electromagnetic valve 2. Like this, a plurality of first solenoid valves 3, a plurality of medicament inlet 7 and a plurality of liquid outlet 8 quantity and position one-to-one, washing liquid inlet 5 and gas air inlet 6 all are connected with main channel 4 through wasing solenoid valve 2, a plurality of medicament inlet 7 and a plurality of liquid outlet 8 all are linked together with main channel 4 through a plurality of corresponding first solenoid valves 3, can set up a plurality of medicament inlet 7, liquid outlet 8 and first solenoid valve 3 of corresponding number according to the kind of monomer reagent and the kind of auxiliary reagent in the DNA synthesis during the use, every first solenoid valve 3 can control the intercommunication of corresponding medicament inlet 7 and liquid outlet 8 and main channel 4. When in normal use, after a certain reagent enters from the reagent liquid inlet 7, the corresponding first electromagnetic valve 3 is switched by a valve, so that the reagent directly flows out from the corresponding liquid outlet 8; when a pipeline and a needle corresponding to a certain reagent are required to be cleaned by using cleaning liquid, after the cleaning liquid enters from a cleaning liquid inlet 5, a cleaning electromagnetic valve 2 is switched through a valve, so that the cleaning liquid directly enters a main channel 4, at the moment, a first electromagnetic valve 3 corresponding to the reagent is switched through the valve, so that a liquid outlet 8 corresponding to the reagent is communicated with the main channel 4, and in this way, the cleaning liquid enters the liquid outlet 8 corresponding to the reagent after flowing through the main channel 4, and further, the cleaning of the corresponding pipeline and the needle of the reagent dispensing device is realized; when the pipeline and the needle corresponding to a certain reagent need to be cleaned by inert protective gas, after the inert protective gas enters from the gas inlet 6, the cleaning electromagnetic valve 2 is switched through a valve, so that the inert protective gas directly enters into the main channel 4, at the moment, the first electromagnetic valve 3 corresponding to the reagent is switched through a valve, so that the liquid outlet 8 corresponding to the reagent is communicated with the main channel 4, and thus, the inert protective gas enters the liquid outlet 8 corresponding to the reagent after flowing through the main channel 4, and further, the cleaning of the corresponding pipeline and the needle of the reagent dispensing device is realized. Each reagent corresponds to the respective reagent liquid inlet 7, liquid outlet 8 and first solenoid valve 3, so that cleaning of the pipeline and needle of each reagent dispensing device by the cleaning liquid and the inert shielding gas can be realized by controlling the switching of the valves of the cleaning solenoid valve 2 and the corresponding first solenoid valve 3.
The invention relates to a cleaning electromagnetic valve combination device for a DNA synthesizer, which is shown in fig. 1-3, and can be based on the technical proposal described above: the electromagnetic valve seat 1 is provided with a first small hole group and a plurality of rows of second small hole groups, the first small hole group and the plurality of rows of second small hole groups are connected through the main channel 4, the position of the first small hole group corresponds to the cleaning electromagnetic valve 2, the first small hole group corresponds to the cleaning liquid inlet 5 and the gas inlet 6, the positions of the plurality of rows of second small hole groups correspond to the plurality of first electromagnetic valves 3 respectively, and the plurality of rows of second small hole groups are connected with the corresponding plurality of medicament inlets 7 and the corresponding plurality of liquid outlets 8. In this way, the electromagnetic valve seat 1 is also provided with a first small hole group corresponding to the cleaning electromagnetic valve 2 and a plurality of rows of second small hole groups corresponding to the first electromagnetic valves 3, the first small hole group is connected with the main channel 4, the cleaning liquid inlet 5 and the gas inlet 6, and the cleaning electromagnetic valve 2 mainly controls the cleaning liquid to enter the main channel 4 from the cleaning liquid inlet 5 or the inert protective gas to enter the main channel 4 from the gas inlet 6 by controlling the communication condition of the first small hole group with the main channel 4, the cleaning liquid inlet 5 and the gas inlet 6; the second small hole groups are connected with the main channel 4, the medicament liquid inlets 7 and the liquid outlets 8, the first electromagnetic valves 3 are used for controlling the communication conditions of the second small hole groups with the main channel 4, the medicament liquid inlets 7 and the liquid outlets 8, controlling each reagent to directly flow out of the corresponding liquid outlets 8 after entering from the corresponding liquid inlets, and further controlling the cleaning liquid or inert protective gas to flow out of the liquid outlets 8 after flowing through the main channel 4, so that the cleaning of each pipeline and the needle head is realized.
The invention relates to a cleaning electromagnetic valve combination device for a DNA synthesizer, which is shown in fig. 1-3, and can be based on the technical proposal described above: the first small hole group comprises a 1 st small hole 9, a 1 st small hole 10, a 1 st small hole 3 and a 1 st small hole 11, the 1 st small hole 9 is communicated with the gas inlet 6, the 1 st small hole 10 is communicated with the main channel 4, and the 1 st small hole 11 is communicated with the cleaning liquid inlet 5. Thus, the 1 st to 1 st small hole 9 is communicated with the gas inlet 6, the 1 st to 2 nd small hole 10 is communicated with the main channel 4, the 1 st to 3 rd small hole 11 is communicated with the cleaning liquid inlet 5, when the inert protective gas enters from the gas inlet 6 and then enters the 1 st to 1 st small hole 9, the cleaning electromagnetic valve 2 is switched by the valve to enable the 1 st to 1 st small hole 9 to be communicated with the 1 st to 2 nd small hole 10, and the inert protective gas directly enters the main channel 4 because the 1 st to 2 nd small hole 10 is communicated with the main channel 4; when the cleaning liquid enters the 1 st to 3 rd small holes 11 from the cleaning liquid inlet 5, the cleaning electromagnetic valve 2 is switched by the valve to enable the 1 st to 3 rd small holes 11 to be communicated with the 1 st to 2 nd small holes 10, and the cleaning liquid can directly enter the main channel 4 because the 1 st to 2 nd small holes 10 are communicated with the main channel 4.
The invention relates to a cleaning electromagnetic valve combination device for a DNA synthesizer, which is shown in fig. 1-3, and can be based on the technical proposal described above: the second small hole group comprises a plurality of 2-1 small holes 12, a plurality of 2-2 small holes 13 and a plurality of 2-3 small holes 14, the 2-1 small holes 12 are communicated with the main channel 4, the 2-2 small holes 13 are respectively communicated with the corresponding liquid outlets 8, and the 2-3 small holes 14 are respectively communicated with the corresponding liquid inlets 7. Thus, when cleaning liquid is used for cleaning a certain pipeline and a needle head thereof, the 2-1 small hole 12 is communicated with the main channel 4, the corresponding 2-2 small hole 13 is communicated with the corresponding liquid outlet 8, the corresponding first electromagnetic valve 3 is controlled to enable the 2-1 small hole 12 to be communicated with the 2-2 small hole 13, after the cleaning liquid flows through the main channel 4, the corresponding liquid outlet 8 flows out, and further cleaning liquid is used for cleaning the pipeline and the needle head, when inert protective gas is used for cleaning a certain pipeline and the needle head thereof, the 2-1 small hole 12 is communicated with the main channel 4, the corresponding 2-2 small hole 13 is communicated with the corresponding liquid outlet 8, the corresponding first electromagnetic valve 3 is controlled to enable the 2-1 small hole 12 to be communicated with the 2-2 small hole 13, and then inert protective gas flows out from the corresponding liquid outlet 8 after passing through the main channel 4, and further cleaning of the inert protective gas is realized, and each pipeline and the needle head is cleaned due to the fact that each first electromagnetic valve 3 is respectively controls the communication of each pipeline.
The invention relates to a cleaning electromagnetic valve combination device for a DNA synthesizer, which is shown in fig. 1-3, and can be based on the technical proposal described above: when the cleaning electromagnetic valve 2 is powered off, the 1 st-3 rd small hole 11 is communicated with the 1 st-2 nd small hole 10, and when the cleaning electromagnetic valve 2 is powered on, the 1 st-1 st small hole 9 is communicated with the 1 st-2 nd small hole 10. Thus, by controlling the power on and off of the cleaning solenoid valve 2, whether the 1 st-2 nd small hole 10 is communicated with the 1 st-1 st small hole 9 or the 1 st-3 rd small hole 11 can be realized, namely, whether inert protective gas or cleaning liquid is selected to clean each pipeline and each needle head by controlling the power on and off of the cleaning solenoid valve 2.
The invention relates to a cleaning electromagnetic valve combination device for a DNA synthesizer, which is shown in fig. 1-3, and can be based on the technical proposal described above: when the first electromagnetic valves 3 are powered off, the 2-3 small holes 14 are communicated with the 2-2 small holes 13, and when the first electromagnetic valves 3 are powered on, the 2-1 small holes 12 are communicated with the 2-2 small holes 13. In this way, by controlling the power on and off of the plurality of first electromagnetic valves 3, it is possible to realize whether the corresponding plurality of 2-2 small holes 13 are communicated with the corresponding plurality of 2-1 small holes 12 or with the corresponding plurality of 2-3 small holes 14, i.e. the cleaning of the respective pipes and needles is realized by controlling the power on of the plurality of first electromagnetic valves 3.
The invention relates to a cleaning electromagnetic valve combination device for a DNA synthesizer, which is shown in fig. 1-3, and can be based on the technical proposal described above: the first electromagnetic valves 3 and the cleaning electromagnetic valves 2 are two-position three-way electromagnetic valves. Thus, the two-position three-way electromagnetic valve can realize the communication or closing of each pipeline through valve switching.
The invention relates to a cleaning electromagnetic valve combination device for a DNA synthesizer, which is shown in fig. 1-3, and can be based on the technical proposal described above: the cleaning liquid inlet 5 and the gas inlet 6 are correspondingly arranged at two sides of the electromagnetic valve seat 1 and distributed on a vertical axis. Like this, washing liquid inlet 5 and gas air inlet 6 distribute in the both sides of solenoid valve seat 1 to be a vertical axis, the design of one-to-one is succinct pleasing to the eye, in addition the timely discovery trouble of being convenient for.
The invention relates to a cleaning electromagnetic valve combination device for a DNA synthesizer, which is shown in fig. 1-3, and can be based on the technical proposal described above: the medicament liquid inlets 7 and the liquid outlets 8 are correspondingly arranged on two sides of the electromagnetic valve seat 1 and distributed on a vertical line. Like this, a plurality of medicament inlet 7 and a plurality of liquid outlet 8 distribute in the both sides of solenoid valve seat 1 to be a vertical axis, the design of one-to-one is succinct pleasing to the eye, and the trouble is in time found in the convenience moreover.
The foregoing description of the preferred embodiments of the invention is not intended to limit the invention to the precise form disclosed, and any such modifications, equivalents, and alternatives falling within the spirit and scope of the invention are intended to be included within the scope of the invention.
Claims (6)
1. A wash solenoid valve composite set for DNA synthesizer, its characterized in that: the cleaning device comprises an electromagnetic valve seat (1), a cleaning electromagnetic valve (2) and a plurality of first electromagnetic valves (3), wherein a main channel (4), a cleaning liquid inlet (5), a gas inlet (6), a plurality of medicament liquid inlets (7) and a plurality of liquid outlets (8) are formed in the electromagnetic valve seat (1), the positions of the plurality of first electromagnetic valves (3), the positions of the plurality of medicament liquid inlets (7) and the positions of the plurality of liquid outlets (8) are in one-to-one correspondence, the medicament liquid inlets (7) and the liquid outlets (8) are connected with the main channel (4) through the corresponding first electromagnetic valves (3), and the cleaning liquid inlets (5) and the gas inlet (6) are connected with the main channel (4) through the cleaning electromagnetic valves (2);
the electromagnetic valve seat (1) is provided with a first small hole group and a plurality of rows of second small hole groups, the first small hole group and the plurality of rows of second small hole groups are connected through the main channel (4), the position of the first small hole group corresponds to the cleaning electromagnetic valve (2), the first small hole group is connected with the cleaning liquid inlet (5) and the gas inlet (6), the positions of the plurality of rows of second small hole groups correspond to the plurality of first electromagnetic valves (3), and the plurality of rows of second small hole groups are connected with the corresponding plurality of medicament liquid inlets (7) and the plurality of liquid outlets (8);
the first small hole group comprises a 1 st small hole (9), a 1 st small hole (10) and a 1 st small hole (11), the 1 st small hole (9) is communicated with the gas inlet (6), the 1 st small hole (10) is communicated with the main channel (4), and the 1 st small hole (11) is communicated with the cleaning liquid inlet (5);
the second small hole group comprises a plurality of 2-1 small holes (12), a plurality of 2-2 small holes (13) and a plurality of 2-3 small holes (14), the 2-1 small holes (12) are communicated with the main channel (4), the 2-2 small holes (13) are respectively communicated with the corresponding liquid outlets (8), and the 2-3 small holes (14) are respectively communicated with the corresponding liquid inlets (7).
2. The combination cleaning solenoid valve apparatus for a DNA synthesizer according to claim 1, wherein: when the cleaning electromagnetic valve (2) is powered off, the 1 st-3 rd small hole (11) is communicated with the 1 st-2 nd small hole (10), and when the cleaning electromagnetic valve (2) is powered on, the 1 st-1 st small hole (9) is communicated with the 1 st-2 nd small hole (10).
3. The combination cleaning solenoid valve apparatus for a DNA synthesizer according to claim 2, wherein: when the first electromagnetic valves (3) are powered off, the 2 nd-3 small holes (14) are communicated with the 2 nd-2 small holes (13), and when the first electromagnetic valves (3) are powered on, the 2 nd-1 small holes (12) are communicated with the 2 nd-2 small holes (13).
4. A cleaning solenoid valve assembly for a DNA synthesizer according to any one of claims 1 to 3, wherein: the plurality of first electromagnetic valves (3) and the cleaning electromagnetic valve (2) are two-position three-way electromagnetic valves.
5. The combination cleaning solenoid valve apparatus for a DNA synthesizer according to claim 1, wherein: the cleaning liquid inlet (5) and the gas inlet (6) are correspondingly arranged on two sides of the electromagnetic valve seat (1) and are distributed on a vertical axis.
6. The combination cleaning solenoid valve apparatus for a DNA synthesizer according to claim 1, wherein: the medicament liquid inlets (7) and the liquid outlets (8) are correspondingly arranged on two sides of the electromagnetic valve seat (1) and distributed on a vertical line.
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| CN201910776412.7A CN110369409B (en) | 2019-08-22 | 2019-08-22 | A wash solenoid valve composite set for DNA synthesizer |
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| CN205056577U (en) * | 2015-10-20 | 2016-03-02 | 山东赢创机械有限公司 | System for wash and thoughtlessly glue aircraft nose pipeline |
| CN106167759A (en) * | 2016-08-26 | 2016-11-30 | 江苏领坤生物科技有限公司 | A kind of gas liquid-way system for DNA synthesizer |
| CN106220700B (en) * | 2016-08-26 | 2019-05-14 | 江苏领坤生物科技有限公司 | A kind of high throughput DNA synthesizer |
| CN209041747U (en) * | 2018-11-21 | 2019-06-28 | 深圳市鼎邦自动化设备有限公司 | A kind of solenoid valve pedestal |
| CN210546828U (en) * | 2019-08-22 | 2020-05-19 | 北京擎科生物科技有限公司 | A wash solenoid valve composite set for DNA synthesizer |
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