CN110354390A - A kind of diabetes Wound healing preparation and its application - Google Patents

A kind of diabetes Wound healing preparation and its application Download PDF

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Publication number
CN110354390A
CN110354390A CN201910518111.4A CN201910518111A CN110354390A CN 110354390 A CN110354390 A CN 110354390A CN 201910518111 A CN201910518111 A CN 201910518111A CN 110354390 A CN110354390 A CN 110354390A
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China
Prior art keywords
wound
diabetes
wound healing
consolidant
water
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CN201910518111.4A
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Chinese (zh)
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杨国锋
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Individual
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Individual
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Priority to CN201910518111.4A priority Critical patent/CN110354390A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/44Applying ionised fluids

Abstract

The invention discloses a kind of diabetes Wound healing preparation and its application, the consolidant is the acidic electrolytic water that OPR value is greater than 1100mV.Provided by the invention kind of diabetes Wound healing preparation, fast and effeciently make to form a sterile environment around wound and wound using physical principle, then the high potential held by reagent itself, to activate nerve cell, it improves the immunity of the human body and self-repairing capability, to have the function that quick healing of cut;And the surface of a wound disinfection it is suitable for various wounds, burn etc. not more, it can not only clean the surface of a wound, but also energy sterilization, and there are also the regenerated efficiency of cell tissue is promoted, hemostasis, analgesic, anti-inflammatory and excellent of reducing swelling, wound healing are fast.

Description

A kind of diabetes Wound healing preparation and its application
Technical field
The present invention relates to treating diabetes field more particularly to a kind of diabetes Wound healing preparation and its applications.
Background technique
All life phenomenon (muscular movement, brain excitement, inhibition, nerve conduction) is all related with the transmitting of electronics, such as: blood Contain the plurality of inorganic salt substance such as water and potassium, sodium, magnesium, calcium in pipe, when the magnetic line of force and blood vessel are at movement in vertical direction, just produces Raw electromagnetic hydroimechanics phenomenon, generates micro-current, magnetic field can lead to the variation of biological electricity and matter, have paramagnet in human body Interaction between the element that (iron, oxygen, magnesium etc.) can be magnetized, and magnetize accelerates, and metabolic function is strengthened.Human body magnetic Field enhancing, can be such that mononuclear phagocyte system function reinforces, leucocyte is just active, healthy and strong, can tell on to inflammatory conditions.
Experiments have shown that human body extra electric field (magnetic field), the influence to human body electric field (magnetic field) can be stopped with activating microcirculation and removing stasis medicinal, detumescence Bitterly, enhance muscles and bones, balanced human's bio-electric field, improve the immunity of the human body and self-repairing capability, activation nerve cell restore to pass Lead function.There is charge by the cell that outer wall inner wall forms, there is voltage difference between inner wall and outer wall, normal condition voltage difference is 0, When being stimulated by certain condition, inside and outside Wall charge is different, generates micro voltage difference and is known as biological micronormal.
Poor wound healing is a complication of diabetes, may cause amputation when serious, it has also become diabetic The highest disease of admission rate, but its exact molecular mechanism is unclear.It has now been found that there are many when diabetes occur Molecule and cell function are impaired, such as growth factor, nitric oxide, active oxygen species, matrix metalloproteinase, m icroRNA, interior Skin progenitor cells etc., it is bad to eventually lead to diabetes wound healing.In addition, if wound occurs in diabetic pastes wound immediately Patch will cause the phenomenon that local temperature increases, and the relatively high environment of temperature, bacterium and germ are easier to breed, in addition patient of diabetes The refractory conjunction of person wound itself, just will appear minor cut or wound become larger wound the phenomenon that, still, do not paste bandage, equally will also result in thin The multilayer subinfection of bacterium and virus, result are also the same.
Summary of the invention
The present invention is a kind of diabetes Wound healing preparation for solving that the above problem in the prior art proposes and its application.
Diabetes Wound healing preparation provided by the invention, shape around wound and wound is fast and effeciently made using physical principle At a sterile environment, then improved the immunity of the human body by the high potential that reagent itself is held to activate nerve cell And self-repairing capability, to have the function that quick healing of cut.
To achieve the above object, the invention adopts the following technical scheme:
The first aspect of the invention is to provide a kind of diabetes Wound healing preparation, and the consolidant is that OPR value is greater than The acidic electrolytic water of 1100mV.
Further, in the diabetes Wound healing preparation, the OPR value of the acidic electrolytic water is 1200- 1500mV。
Further, in the diabetes Wound healing preparation, the pH value of the acidic electrolytic water is 1.5-2.8.
Further, in the diabetes Wound healing preparation, the pH value of the acidic electrolytic water is 1.8-2.2.
Further, in the diabetes Wound healing preparation, it is described state acidic electrolytic water the preparation method comprises the following steps: to electricity It solves and potassium chloride and water is added in the electrolytic cell of Water generator, obtain acidic oxidation of the OPR value greater than 1100mV by electrolysis and be electrolysed Water.
It is further preferred that containing active oxygen, institute in the acidic electrolytic water in the diabetes Wound healing preparation Stating active oxygen is generated nascent state elemental oxygen, hydrogen peroxide, ozone isoreactivity oxygen ingredient in electrolytic process.
It is further preferred that also contain effective chlorine in the acidic electrolytic water in the diabetes Wound healing preparation, The effective chlorine is the hypochlorous acid and chlorine that electrolytic process directly generates.
The second aspect of the invention is to provide the answering in the wound for the treatment of diabetic of consolidant described in one kind With.
Further, in the application in the consolidant in the wound for the treatment of diabetic, the wound is wound Wound or burn wound.
Further, in the application in the consolidant in the wound for the treatment of diabetic, when the wound or The area of burn wound is less than 1cm3When, the surface of a wound is sprayed on using the consolidant, then wrapping nursing, two times a day; When the area of wound or burn wound is greater than 1cm3When, the surface of a wound is cleaned using the consolidant, and wrap up nursing, Three to four times on the one.
The present invention by adopting the above technical scheme, compared with prior art, has the following technical effect that
Provided by the invention kind of diabetes Wound healing preparation can preferably control infected wound caused by diabetes, protect Hold surface of a wound cleaning, promote the formation of granulation, wound for diabetic and skin-grafting are survived relatively difficult infection, the surface of a wound into The preoperative disinfection treatment of row, it is highly effective;And the surface of a wound disinfection suitable for various wounds, burn etc. not more, it can both be cleaned The surface of a wound, and energy sterilization, there are also promote the regenerated efficiency of cell tissue, hemostasis, analgesic, anti-inflammatory and excellent of reducing swelling, wound Face healing is fast.
Specific embodiment
The present invention is described in more detail below by specific embodiment, for a better understanding of the present invention, But following embodiments are not intended to limit the scope of the invention.
Embodiment 1
The present embodiment provides a kind of diabetes Wound healing preparation, the consolidant is acidity electricity of the OPR value greater than 1100mV Xie Shui.OPR value (oxidation-reduction potential) is an important indicator in water quality, although it is unable to the quality of independent reaction water quality, It is that can integrate other water quality indicators to reflect the ecological environment in aquarium system.The diabetes Wound healing preparation, utilizes physics Principle fast and effeciently makes to form a sterile environment around wound and wound, the height electricity then held by reagent itself Position improves the immunity of the human body and self-repairing capability to activate nerve cell, to have the function that quick healing of cut.
In the present embodiment, it is well known that the ORP value that the microbe survivals such as bacterium, virus are relied on be 400mV~ 900mV, and the required acidic electrolytic water ORP (1100mV or more) with higher used of the present invention, after being contacted with microorganism Capture electronics rapidly, interfere the balance of cell, change the potential difference inside and outside film, lead to the permeability of bacterial cell membrane, increases thin The destruction of born of the same parents' metabolism kills microorganism to reach;Enzyme needed for can also inhibiting rapidly, destroying bacterial growth;And it is demonstrate,proved through experiment Bright ORP is the principal element for making bacteria inactivation rate.Preferably, the OPR value of the acidic electrolytic water is 1200-1500mV.More Preferably, the OPR value of the acidic electrolytic water is 1280-1320mV.
It in the present embodiment, research has shown that, is that the microorganisms such as bacterium, virus are most suitable for the pH value of existence generally 3.0 ~10.0, and the low ph value of consolidant provided in this embodiment has been more than the scope of any pathogenic microorganism, so, it is various The microorganism of various kinds can not survive in such a case.The present embodiment uses the pH value of the acidic electrolytic water for 1.5- 2.8;Preferably, the pH value of the acidic electrolytic water is 1.8-2.2;It is further preferable that the pH value of the acidic electrolytic water is 2.0。
In the present embodiment, acidic electrolytic water used by the present embodiment the preparation method comprises the following steps: to device for producing electrolytic water Potassium chloride and water are added in electrolytic cell, obtains the acidic oxidation electrolysis water that OPR value is greater than 1100mV by electrolysis.Acidic oxidation electricity The low ph value 1.5-2.8 of Xie Shui can not only inhibit bacterial growth, and can assist in hypochlorous acid gone directly by cell membrane it is subtle In biology, the hypochlorous acid in another aspect acidic oxidation electrolysis water can penetrate and destroy cell membrane, life in inducing microbial body Viability oxygen further destroys the macromolecular structure of nucleic genetic material, cell metabolism enzyme and protein;Acidic oxidation electricity Xie Shui has high redox potential (> 1100mV) can direct oxidation cell membrane while changing microbial cell film potential The sulfydryl of upper macromolecular compound, causes permeability of cell membrane to enhance, to destroy intracellular normal metabolic processes, causes Keep cellular content spilling, cell molten.
In the present embodiment, active oxygen is contained in the acidic electrolytic water, the active oxygen is produced in electrolytic process Nascent state elemental oxygen, hydrogen peroxide, ozone isoreactivity oxygen ingredient, it has bactericidal effect, but unstable, it is difficult to protect for a long time Deposit, but save three months or more still have bactericidal effect, illustrating active oxygen not is the sterilization leading role of this product, only rise auxiliary Effect.
In the present embodiment, effective chlorine is also contained in the acidic electrolytic water, the effective chlorine is that electrolytic process is directly raw At hypochlorous acid and chlorine.It can not only have an effect with the cell wall of microorganism, can also invade and occur into the cell with albumen Oxidation destroys its phosphate dehydrogenase, keeps glycometabolism unbalance, bacterium protein is caused to aoxidize.
Embodiment 2
Application of the consolidant described in one kind in the wound for the treatment of diabetic is provided, the wound is wound or burning Hurt the surface of a wound.The consolidant can preferably control infected wound caused by diabetes, keep surface of a wound cleaning, promote the shape of granulation At wound and relatively difficult infection of surviving of making skin graft, the surface of a wound for diabetic carry out preoperative disinfection treatment, have very much Effect;And the surface of a wound disinfection suitable for various wounds, burn etc. not more, it can not only clean the surface of a wound, but also can sterilization, also rush Into the regenerated efficiency of cell tissue, hemostasis, analgesic, anti-inflammatory and detumescence excellent, wound healing are fast.
In the present embodiment, it is preferable that in application method of the consolidant in the wound for the treatment of diabetic are as follows: When the area of the wound or burn wound is less than 1cm3When, the surface of a wound is sprayed on using the consolidant, then wrapping shield Reason, two times a day;When the area of wound or burn wound is greater than 1cm3When, the surface of a wound is carried out using the consolidant clear It washes, and wraps up nursing, three to four times on the one.The consolidant is fast and effeciently made to have around wound and wound first with physical principle One sterile environment, the high potential then held by reagent itself, to activate nerve cell, improve the immunity of the human body and Self-repairing capability, to have the function that quick healing of cut.
Specific embodiments of the present invention are described in detail above, but it is merely an example, the present invention is simultaneously unlimited It is formed on particular embodiments described above.To those skilled in the art, any couple of present invention carries out equivalent modifications and Substitution is also all among scope of the invention.Therefore, without departing from the spirit and scope of the invention made by equal transformation and Modification, all should be contained within the scope of the invention.

Claims (10)

1. a kind of diabetes Wound healing preparation, which is characterized in that the consolidant is the acidic electrolysis that OPR value is greater than 1100mV Water.
2. diabetes Wound healing preparation according to claim 1, which is characterized in that the OPR value of the acidic electrolytic water is 1200-1500mV。
3. diabetes Wound healing preparation according to claim 1, which is characterized in that the pH value of the acidic electrolytic water is 1.5-2.8。
4. diabetes Wound healing preparation according to claim 3, which is characterized in that the pH value of the acidic electrolytic water is 1.8-2.2。
5. diabetes Wound healing preparation according to claim 1, which is characterized in that the preparation side for stating acidic electrolytic water Method are as follows: potassium chloride and water are added into the electrolytic cell of device for producing electrolytic water, obtains the acidity that OPR value is greater than 1100mV by electrolysis EO water.
6. diabetes Wound healing preparation according to claim 5, which is characterized in that containing active in the acidic electrolytic water Oxygen, the active oxygen are generated nascent state elemental oxygen, hydrogen peroxide, ozone isoreactivity oxygen ingredient in electrolytic process.
7. diabetes Wound healing preparation according to claim 1, which is characterized in that also have in the acidic electrolytic water Chlorine is imitated, the effective chlorine is the hypochlorous acid and chlorine that electrolytic process directly generates.
8. a kind of application such as the described in any item consolidants of claim 1-9 in the wound for the treatment of diabetic.
9. application of the consolidant according to claim 8 in the wound for the treatment of diabetic, which is characterized in that described Wound is wound or burn wound.
10. application of the consolidant according to claim 9 in the wound for the treatment of diabetic, which is characterized in that when The area of the wound or burn wound is less than 1cm3When, the surface of a wound is sprayed on using the consolidant, then wrapping nursing, Two times a day;When the area of wound or burn wound is greater than 1cm3When, the surface of a wound is cleaned using the consolidant, and Wrapping nursing, three to four times on the one.
CN201910518111.4A 2019-06-14 2019-06-14 A kind of diabetes Wound healing preparation and its application Pending CN110354390A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113244264A (en) * 2021-06-07 2021-08-13 青岛威巴克生物技术有限公司 Novel protective agent for promoting healing of ulcer surface

Citations (3)

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Publication number Priority date Publication date Assignee Title
CN1395489A (en) * 2000-01-12 2003-02-05 诺华科尔制药公司 Physiologically balanced ionized acidic solution and methodology for use in wound healing
US20140178500A1 (en) * 2009-06-17 2014-06-26 Apr Nanotechnologies S.A. Methods of treating outer eye disorders using high orp acid water and compositions thereof
CN109395068A (en) * 2018-11-26 2019-03-01 浙江舒是生物科技有限公司 A kind of refractory wound Special sterilizing liquid

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1395489A (en) * 2000-01-12 2003-02-05 诺华科尔制药公司 Physiologically balanced ionized acidic solution and methodology for use in wound healing
US20140178500A1 (en) * 2009-06-17 2014-06-26 Apr Nanotechnologies S.A. Methods of treating outer eye disorders using high orp acid water and compositions thereof
CN109395068A (en) * 2018-11-26 2019-03-01 浙江舒是生物科技有限公司 A kind of refractory wound Special sterilizing liquid

Non-Patent Citations (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113244264A (en) * 2021-06-07 2021-08-13 青岛威巴克生物技术有限公司 Novel protective agent for promoting healing of ulcer surface

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