CN110322963A - A kind of newborn's Inherited Metabolic Disorders determination method, apparatus and system - Google Patents
A kind of newborn's Inherited Metabolic Disorders determination method, apparatus and system Download PDFInfo
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- G—PHYSICS
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- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
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Abstract
The invention proposes a kind of newborn's Inherited Metabolic Disorders determination methods, apparatus and system, computer system is created, disease database, the interpretation mode that doctor combines, interpretation more fast and accurately can be carried out to newborn's Inherited Metabolic Disorders tandem mass spectrum testing result and provide accurate conclusion, entire workflow realizes comprehensive data, interpretation process is enabled to be easier to trace to the source and later period Comparison Study repeatedly, it can greatly avoid that retrospective analysis can not be carried out because the artificial interpretation later period forgets, this system realizes the automation of higher degree using the mode of man-computer cooperation, greatly reduce the investment of human cost, with increasing for data volume, and system is continued to optimize, the interpretation of Artificial intelligence is possibly even realized in later newborn's Inherited Metabolic Disorders tandem mass spectrum testing result interpretation.
Description
Technical field
The present invention relates to field of medical equipment, especially a kind of newborn's Inherited Metabolic Disorders determination method, device and
System.
Background technique
Inherited Metabolic Disorders be because maintain body eubolism necessary to certain enzymes being made of polypeptide and (or) albumen, by
Genetic defect occurs for body, carrier and membrane pump biosynthesis, that is, caused by the gene mutation for encoding this kind of polypeptide (albumen)
Disease, also known as hereditary metabolic disorder or inborn error of metabolism.
The annual newborn population in China is about between 1,600 ten thousand to 2,000 ten thousand, and wherein Inherited Metabolic Disorders infant is up to 40 ten thousand to 50
Ten thousand, the birth of a large amount of Inherited Metabolic Disorders children brings huge burden for society and family, will certainly seriously affect country
Politics, economic, humane development strategy.Since China is national and medical personnel understands the knowledge of Inherited Metabolic Disorders
Very little, understanding is insufficient, and China proposed the concept of neonatal screening since 1981, promotes in legislation in 1994, using law
Form accelerate universal process.
In the extension process of many years, for Inherited Metabolic Disorders detection usually still: detection department is according to Testing index
Measured value provide examining report, by clinician according to examining report carry out Diseases diagnosis.But Inherited Metabolic Disorders are many kinds of, so far
The Inherited Metabolic Disorders type that the present has found is more than 3000 kinds.There is number using the Inherited Metabolic Disorders index of tandem mass spectrometry detection simultaneously
As many as ten, because individual difference will appear hundreds of different testing result combination, and then represent different classes of heredity metabolism
Different risks sick or that may be present.Different clinicians is not only different to Inherited Metabolic Disorders degree of understanding, Er Qieqi
The Inherited Metabolic Disorders type grasped also is not quite similar, if only passing through by veteran laboratory physician or clinician
Comparative analysis obtains correct conclusion from hundreds of conclusion repeatedly, not only takes time and effort but also limitation is very strong, and experience is insufficient
Doctor be unable to complete the accurate interpretation of its result.
Documents CN201710170285.7 discloses a kind of neonatal hereditary diease metabolic disease screening method, and this method is
It will test sample to be compared with the achievement data in medical data base, judge index in the detection sample and medical data base
Whether data match, if so, the screening data of the corresponding Inherited Metabolic Disorders of the matched achievement data are exported, if it is not, defeated
Non- illness out.There are two problem, problems one: although the judgement for alleviating clinician from a kind of degree is strong for the documents
Degree, but documents CN201710170285.7 output result is two kinds: illness or not illness, output result is too dogmatic,
Disease event can not be described accurately very much.A kind of such as Inherited Metabolic Disorders index of different role by multiple collectively forms, but
It is only that wherein some Indexes Abnormality or multiple auxiliary characteristics not played a decisive role are abnormal, this can not represent infant and centainly suffer from
Disease.Problem two: specifically how this database is established.
It can be seen that in the prior art, although part body has been equipped with brief Inherited Metabolic Disorders tandem mass spectrum
Examining report system, but it is to carry out simplicity of explanation to Testing index in the comparison analysis of not large database concept,
Interpretation result is not plain professional, is very easy to error.
Summary of the invention
To solve the above-mentioned problems, the invention proposes a kind of newborn's Inherited Metabolic Disorders determination method, the sides
Method includes the following steps: S1: obtaining sample data;S2: distinguishing according to sample data, if sample data exception, then holds
Row step S3;If sample data is normal, step S6 is executed;S3: according to each index in all kinds of Inherited Metabolic Disorders metabolic pathways
Effect degree carries out first step classification, obtains first time classification results;S4: multi objective joint risk assessment classification is carried out, is obtained
Second of classification results;S5: comprehensive first time classification results and second of classification results provide final classification of diseases result;
S6: terminate.
It include, by Quality Control Analysis method, analyzing sample data in the S1, if sample data does not conform to
Lattice then carry out resampling or reinspection, otherwise enter step S2.
The specific implementation of the S2 are as follows:
S21: the index for influencing Inherited Metabolic Disorders and the factor index that normal interpretation may be influenced are read;
S22: differentiating whether the index in S21 is all normal, if all normal, is determined as that index is normal or probability
It is very low, disease is not prompted, step S6 is executed;Otherwise, it is extremely suspicious that Inherited Metabolic Disorders are regarded as, execute step S3.
The specific implementation of the S3 are as follows:
S31: certain Inherited Metabolic Disorders being had confirmed that according to clinical research are mainly caused by what Indexes Abnormality, screening and the something lost
Pass on relevant index of declining office, invitation, etc. on account of illness;
S32: distinguishing the effect degree of index in the metabolic process, and the first time point of data is carried out according to the classification
Class.
The index to play a major role if it exists is raised and lowered, then it is assumed that results abnormity occurs very related to disease.Again
First time classification results are determined in conjunction with Indexes Abnormality degree and Clinical signs;Otherwise, step S4 is executed.
Specifically, Inherited Metabolic Disorders refer to a kind of hereditary disease for having metabolic function defect, mostly single gene inheritance disease, including
Metabolized macromolecules class disease (such as lysosomal storage disease (thirties kinds of diseases), mitochondriopathy) and metabolism small molecule class disease are (such as
The metabolic disorders such as amino acid, organic acid, fatty acid related disease).A part of cause of disease of Inherited Metabolic Disorders is caused by gene genetic, also
Some is that the gene mutation day after tomorrow causes.According to clinical research, with Inherited Metabolic Disorders highly relevant index occurs for confirmation, and
By these index typings, our database is used for interpretation, import detection data be in being carried out to the degree of risk of disease, severe
Interpretation.
The specific implementation of the step S4 are as follows:
In the whether judgement for being Inherited Metabolic Disorders, other indexs in addition to index highly relevant in step S3 continue and are
System disease database compare and analyze judgement, it is antenatal in combination with mother, produce when health and nutritional status, newborn take a blood sample
When disease and nutrition condition carry out accurate interpretation.If abnormal index and mother it is antenatal, produce when health and nutritional status, newborn
Nutritional status when blood sampling is related, and prompt is little with hereditary metabolic disorders correlation, is judged as that abnormal prompt disease probability is low;
If situation when excluding mother and newborn's blood sampling is abnormal there are still there is disease indicators, and its anomalous variation is little, then is judged as
It may be slight Inherited Metabolic Disorders, can be paid close attention to or be intervened ahead of time.
Preferably, in the step S1, pass through the sample data of neonatal bleeding of the umbilicus or vola blood.
Preferably, it in the step S6, before end, is provided accordingly according to interpretation result and inspection person's clinical information
It is recommended that and generating report.
Preferably, newborn's Inherited Metabolic Disorders test and analyze device and carry out newborn's something lost using foregoing method
Pass on detection and analysis of declining office, invitation, etc. on account of illness.
Preferably, newborn's Inherited Metabolic Disorders testing and analysis system includes data collection station, newborn's heredity generation
It declines office, invitation, etc. on account of illness and tests and analyzes device;Newborn's Inherited Metabolic Disorders test and analyze device and include data server, analysing terminal, show eventually
End;It is sequentially connected between the data collection station, the data server, the analysing terminal and the display terminal, number
It include data input module and pattern detection module according to acquisition terminal;Data server stores newborn's information bank and disease data
Library;Analysing terminal is generated according to detection data and is reported for obtaining detection data from data server;Display terminal is for showing
Show the examining report of generation;Newborn's Inherited Metabolic Disorders test and analyze device and carry out newborn using foregoing method
Inherited Metabolic Disorders test and analyze.Preferably, newborn's Inherited Metabolic Disorders testing and analysis system include feedback terminal, described point
Electric signal between terminal and the feedback terminal is analysed to connect;Feedback terminal is lost for obtaining Inherited Metabolic Disorders prediction result, feedback
Pass on actual result of declining office, invitation, etc. on account of illness.
The beneficial effects of the present invention are: 1, created computer system, disease database (big data), doctor combine
Interpretation mode, more fast and accurately newborn's Inherited Metabolic Disorders tandem mass spectrum testing result can interpretation and provide
Accurate conclusion.2, disease database covers more than ten ten thousand testing results, confirmed cases also with the time it is progressive increasingly
It is more, so that the interpretation of result can be more and more accurate, it is eventually striking to accurate interpretation;Have for corresponding Conventional wisdom interpretation very big
Supplement and improvement.3, conclusion suggestion is to be conferred to draft jointly by numerical digit authoritative expert, and professional degree authority is higher, can be very big
Limit avoids the omnifarious suggestion that the artificial subjective factor because of different people provides, and brings puzzlement to subsequent interpretation.
4, this system can greatly reduce the throwing of human cost due to high degree of automation, and using the Pattern completion of man-computer cooperation
Enter, so that the workload for needing 5-10 doctor to complete, can be completed by 2-3 people's coupled system.5, complete due to process
Face data enables interpretation process to be easier to trace to the source and later period Comparison Study repeatedly, can greatly avoid because manually sentencing
The later period is read to forget and retrospective analysis can not be carried out.6, later newborn with increasing for data volume and continuing to optimize for system
The interpretation of Artificial intelligence is possibly even realized in youngster's Inherited Metabolic Disorders tandem mass spectrum testing result interpretation.
Detailed description of the invention
Fig. 1 is system construction drawing;
Fig. 2 is the flow chart of the first subseries interpretation;
Fig. 3 is the flow chart of the second subseries interpretation.
Specific embodiment
For a clearer understanding of the technical characteristics, objects and effects of the present invention, this hair of Detailed description of the invention is now compareed
Bright specific embodiment.
As shown in Figure 1, a kind of newborn's Inherited Metabolic Disorders testing and analysis system, loses comprising data collection station, newborn
Passage, which is declined office, invitation, etc. on account of illness, tests and analyzes device;It includes data server, analysing terminal, display that newborn's Inherited Metabolic Disorders, which test and analyze device,
Terminal;It is sequentially connected between the data collection station, the data server, the analysing terminal and the display terminal,
Data collection station includes data input module and pattern detection module;Data server stores newborn's information bank and disease number
According to library;Analysing terminal is generated according to detection data and is reported for obtaining detection data from data server;Display terminal is used for
Show the examining report generated.Newborn's Inherited Metabolic Disorders testing and analysis system includes feedback terminal, the analysing terminal
Electric signal is connect between the feedback terminal;Feedback terminal feeds back heredity metabolism for obtaining Inherited Metabolic Disorders prediction result
Sick actual result.
Data collection station includes data input module and pattern detection module.Data input module is used for will be neonatal
Essential information and health and fitness information input system, perfect information library.Pattern detection module is used for according to neonatal bleeding of the umbilicus or vola
Blood obtains detection data, (connects sample according to newborn's Inherited Metabolic Disorders tandem mass spectrum testing process, generates experimentai batches, sample inspection
Survey, experiment is completed) process on line is completed, and the detection data that will acquire imports data server.Mass spectrum (the Mass
Spectrum so that sample to be tested molecule is gasified, with the beam bombardment gaseous molecular with certain energy, it is made to lose an electricity
Son and become positively charged ion, ion is also possible to fragment into various fragment ions, and all cations are in electric and magnetic fields
It is arranged successively under comprehensive function by mass-to-charge ratio (m/z) size and obtains spectrogram, for detection compound structure (qualitative) and mixed
Object composition (quantitative) is closed, it is tandem mass spectrum that two or more mass spectrums, which link together,.Tandem mass spectrometry is for blood sample
Originally there is certain requirement, it is desirable that blood sampling time carries out after 72 hours and 6 times or more milk of having enough preferably after baby due, mainly
Because if baby does not eat or do not take in enough milk, the concentration of phenylalanine in blood is relatively low, and when detection easily leads to false yin
Property, while blood sampling can avoid the opportunity of physiological thyroid-stimulating hormone rising after birth 72 hours, reduce thyroid hypofunction
The false positive of screening, and the false negative of TSH rising delay infant can be prevented, the blood sampling feelings of data input module typing can be passed through
Condition ensures that blood sample is met the requirements.
Data server stores newborn's information bank and disease database.Newborn's information bank stores neonatal basic letter
Breath, health and fitness information and detection data associated therewith, neonatal essential information and health and fitness information specifically include date of birth
Phase, gender, childbirth options, weight, disease treatment situation, mother's pregnancy period situation, blood sampling situation etc..Disease database storage and something lost
Decline office, invitation, etc. on account of illness relevant indication information and confirmed cases information are passed on, the index includes alanine Ala, leucine
Leu Ile Pro-OH, immunocyte C4, oleic acid C18:1 etc., leucine Leu Ile Pro-OH and maple syrup urine disease
It is related with hydroxyprolinemia, immunocyte C4 and isobutyryl glycinuria, ethyl malonic acid encephalopathy, short chain acyl coacetylase
Dehydrogenase Deficiency is related, oleic acid C18:1 and II type of Carnitine palmitoyltransferase deficiency disease, carnitine-fatty acyl carnitine translocase
Deficiency disease is related, and the indication information includes the corresponding relationship of specific targets and Inherited Metabolic Disorders.Disease database is currently covered
More than 10 ten thousand testing results, and confirmed cases can also gradually increase, so that the interpretation of result can be more and more accurate, it is final real
Now accurate interpretation has very big supplement and improvement for Conventional wisdom interpretation.
Analysing terminal is generated according to detection data and is reported for obtaining detection data from data server, is reported and is lost
Pass on prediction result correlation of declining office, invitation, etc. on account of illness.As shown in figure 3, the specific workflow of analysing terminal is divided into:
1) data detection: population sample Quality Control Analysis is carried out with statistical way to detection data, quality control is closed
Link is analyzed in entering for lattice in next step, and unqualified data need to re-start sampling or reinspection, to guarantee to enter diseases analysis link
Data it is accurate and reliable;
2) data screening: to quality acceptance number, sample is unit accordingly, according to be stored in systemic disease database with
Inherited Metabolic Disorders index of correlation and the other factors index that may influence normal interpretation carry out different with Inherited Metabolic Disorders index of correlation
Category filter whether often;
3) first sentence interpretation: system will test result and match with the essential information of patient, while carry out to testing result preliminary
Interpretation illustrates that newborn is strong if whole indexs, in range of normal value, the preliminary interpretation of testing result is A, index is normal
Health is directly entered output report step, and otherwise, the preliminary interpretation of testing result is B, Indexes Abnormality, enters next node by process
Interpretation;
4) second trial interpretation: by result that first sentence node interpretation is B Indexes Abnormality by the comparison interpretation of index and be
The comparative analysis judgement of system disease database, carries out further interpretation.As shown in Fig. 2, if having 1 or more coupling index not just
In normal reference range, then interpretation is C, related to disease suspicious, is judged into next node;If there is 1 or more disease crucial
Index is not in normal reference value, then interpretation is D, very related to disease, into next node interpretation;
5) a is read in three trials: the progress further accurate interpretation for being C by second trial node interpretation is sentenced by the comparison of index
It reads and judges with the comparative analysis of systemic disease database, health antenatal in conjunction with mother, when producing and nutritional status, newborn
Disease and nutrition condition when blood sampling carry out accurate interpretation.If abnormal index and mother are antenatal, health and nutritional status when producing, new
Nutritional status when raw youngster's blood sampling is related, is judged as E, and prompt is little with hereditary metabolic disorders correlation, is judged as abnormal and mentions
Show that disease probability is low;If there are still have disease indicators exception, and its anomalous variation for situation when excluding mother and newborn's blood sampling
Less, then it is judged as F, prompt may be slight Inherited Metabolic Disorders, can be paid close attention to or be intervened ahead of time.
6) b is read in three trials: second trial node interpretation is classified as D's as a result, by the comparison interpretation and and system of index
The comparative analysis of disease database judges, degree is raised and lowered according to index and combines Clinical signs, carries out accurate interpretation.Refer to
It is very high, interpretation G that degree, which is raised and lowered, or not mark, prompts moderate Inherited Metabolic Disorders;It is bigger that index is raised and lowered degree,
Interpretation is H, prompts severe Inherited Metabolic Disorders.
8) report output: comprehensive by system in conjunction with the essential information of patient, detection data and final diseases analysis suggestion
Examining report display terminal is generated after conjunction to be used to show the examining report generated.
Feedback terminal feeds back Inherited Metabolic Disorders actual result for obtaining Inherited Metabolic Disorders prediction result.Staff according to
Mother and child care network in region is held in the palm, establishes follow-up study network, by the different diagnosis and treatment requirements of screening disease, periodic visit makes a definite diagnosis trouble
The newest health status of infant is updated to data server by feedback terminal by youngster, staff can according to it is different most
Whole interpretation result determines follow-up plan, for example, for three trial read b be in, severe prompt Inherited Metabolic Disorders high risk situation,
It needs to carry out this kind of crowd to make a definite diagnosis tracking after testing result notice, is confirmed whether to be diagnosed as Inherited Metabolic Disorders and be done sth. in advance
Therapy intervention.
Newborn's Inherited Metabolic Disorders testing and analysis system proposed by the present invention divides Testing index by computer system
Analysis compares and the analyses and comparison of disease database, can more accurate interpretation go out the disease directive property of testing result, can be with
It more fast and accurately assists a physician and completes the analysis of testing result and provide analysis and suggestion, avoid doctor and spent by manpower
The a large amount of time carries out the analysis of index and database, saves the time of doctor.At the same time, the system is basic by patient
Information, Testing index, disease database etc. are multiple to be compared repeatedly, and final result is judged by doctor according to clinical manifestation again,
The generation of misinterpretation can be avoided to greatest extent.
Newborn's Inherited Metabolic Disorders testing and analysis system proposed by the present invention has created computer system, disease database
The analysis processing mode that (big data), doctor combine, can be more fast and accurately to newborn's Inherited Metabolic Disorders series connection matter
Spectrum testing result carries out interpretation and provides accurate conclusion.Entire workflow realizes comprehensive data, enables interpretation process
It enough is easier to trace to the source and later period Comparison Study repeatedly, can greatly avoid being looked back because the artificial interpretation later period forgets
Property analysis.This system realizes the automation of higher degree using the mode of man-computer cooperation, so that 2-3 people's coupled system can be complete
The workload completed at 5-10 doctor was needed originally greatly reduces the investment of human cost.With the increasing of data volume
More and system enrich constantly is improved and is optimized, and following newborn's Inherited Metabolic Disorders tandem mass spectrum testing result interpretation is even
The interpretation of Artificial intelligence can be able to achieve.
The above disclosure is only the preferred embodiments of the present invention, cannot limit the right model of the present invention with this certainly
It encloses, therefore equivalent changes made in accordance with the claims of the present invention, is still within the scope of the present invention.
Claims (10)
1. a kind of newborn's Inherited Metabolic Disorders determination method, which is characterized in that described method includes following steps:
S1: sample data is obtained;
S2: distinguishing according to sample data, if Inherited Metabolic Disorders exception, thens follow the steps S3;If non-Inherited Metabolic Disorders
It is abnormal, execute step S6;
S3: first step classification is carried out according to each index primary and secondary degree in all kinds of Inherited Metabolic Disorders metabolic pathways, is obtained for the first time
Classification results;If thening follow the steps S5 without main Indexes Abnormality in first time classification results;It is no to then follow the steps S4;
S4: according to multi objective joint risk assessment classification is carried out, second of classification results is obtained;
S5: comprehensive first time classification results and second of classification results provide final classification of diseases result;S6: terminate.
2. a kind of newborn's Inherited Metabolic Disorders determination method as described in claim 1, which is characterized in that wrapped in the S1
It includes, by Quality Control Analysis method, sample data is analyzed, if sample data is unqualified, carry out resampling or multiple
Inspection, otherwise enters step S2.
3. a kind of newborn's Inherited Metabolic Disorders determination method as described in claim 1, which is characterized in that the tool of the S2
Body implementation are as follows:
S21: the index for influencing Inherited Metabolic Disorders and the factor index that normal interpretation may be influenced are read;
S22: differentiate whether the index in S21 is all normal, if all normal, be determined as that non-Inherited Metabolic Disorders are abnormal, execute
Step S6;Otherwise, Inherited Metabolic Disorders exception is regarded as, step S3 is executed.
4. a kind of newborn's Inherited Metabolic Disorders determination method as described in claim 1, which is characterized in that the tool of the S3
Body implementation are as follows:
S31: certain Inherited Metabolic Disorders being had confirmed that according to clinical research are mainly caused by what Indexes Abnormality, screening and the heredity generation
It declines office, invitation, etc. on account of illness relevant index;
S32: carrying out point of primary and secondary to index, to being main indicator with the index of certain Inherited Metabolic Disorders highlights correlations, loses to certain
Passing on slight associated index of declining office, invitation, etc. on account of illness is secondary index;
S33: distinguishing the effect degree of index in the metabolic process, and the first subseries of data is carried out according to the classification;
Main indicator is raised and lowered if it exists, it is believed that abnormal prompt is very related to disease, and Indexes Abnormality degree and clinic
It characterizes and determines first time classification results;
Otherwise, step S4 is executed.
5. a kind of newborn's Inherited Metabolic Disorders determination method as described in claim 1, which is characterized in that the step S4
Specific implementation are as follows:
Judge by the comparison interpretation of index and with the comparative analysis of systemic disease database, obtain second of classification results,
Disease and nutrition condition when health antenatal in conjunction with mother, when producing and nutritional status, newborn's blood sampling carry out accurate interpretation.If
Nutritional status when abnormal index and mother are antenatal, health and nutritional status, newborn take a blood sample when producing is related, prompts and heredity generation
Thanking property is disease associated less, is judged as that abnormal prompt disease probability is low;If situation when exclusion mother and newborn take a blood sample is still
There are disease indicators exceptions, and its anomalous variation is little, then are judged as to be slight Inherited Metabolic Disorders, can be closed ahead of time
Note is intervened.
6. a kind of newborn's Inherited Metabolic Disorders determination method as described in claim 1, which is characterized in that the step S1
In, pass through the sample data of neonatal bleeding of the umbilicus or vola blood.
7. a kind of newborn's Inherited Metabolic Disorders determination method as described in claim 1, which is characterized in that the step S6
In, before end, according to the cause of disease, corresponding suggestion is provided, and generate report.
8. a kind of newborn's Inherited Metabolic Disorders test and analyze device, which is characterized in that newborn's Inherited Metabolic Disorders detection point
Analysis apparatus carries out the detection and analysis of newborn's Inherited Metabolic Disorders using method described in one of claim 1-7.
9. a kind of newborn's Inherited Metabolic Disorders testing and analysis system, which is characterized in that newborn's Inherited Metabolic Disorders detection point
Analysis system includes data collection station, newborn's Inherited Metabolic Disorders detection and analysis device;
It includes data server, analysing terminal, display terminal that newborn's Inherited Metabolic Disorders, which test and analyze device,;
It is sequentially connected between the data collection station, the data server, the analysing terminal and the display terminal,
Data collection station includes data input module and pattern detection module;
Data server stores newborn's information bank and disease database;
Analysing terminal is generated according to detection data and is reported for obtaining detection data from data server;
Display terminal is used to show the examining report generated;
Newborn's Inherited Metabolic Disorders test and analyze device and carry out newborn's something lost using method described in one of claim 1-7
Pass on detection and analysis of declining office, invitation, etc. on account of illness.
10. a kind of newborn's Inherited Metabolic Disorders testing and analysis system as claimed in claim 9, which is characterized in that the new life
Youngster's Inherited Metabolic Disorders testing and analysis system includes feedback terminal, and electric signal connects between the analysing terminal and the feedback terminal
It connects;
Feedback terminal feeds back Inherited Metabolic Disorders actual result for obtaining Inherited Metabolic Disorders prediction result.
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