CN110301907A - A kind of wearable pulse wave detection device and blood pressure detecting method - Google Patents
A kind of wearable pulse wave detection device and blood pressure detecting method Download PDFInfo
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- CN110301907A CN110301907A CN201910552010.9A CN201910552010A CN110301907A CN 110301907 A CN110301907 A CN 110301907A CN 201910552010 A CN201910552010 A CN 201910552010A CN 110301907 A CN110301907 A CN 110301907A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
- A61B5/02125—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics of pulse wave propagation time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02141—Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
- A61B5/681—Wristwatch-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/725—Details of waveform analysis using specific filters therefor, e.g. Kalman or adaptive filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0204—Operational features of power management
- A61B2560/0214—Operational features of power management of power generation or supply
Abstract
The invention discloses a kind of wearable pulse wave detection device and blood pressure detecting methods, including the annular body for wearing；The inner surface of annular body is arranged in first flexible piezoelectric sensors, the first flexible piezoelectric sensors, contacts for the first detection position with user；The outer surface of annular body is arranged in second flexible piezoelectric sensors, the second flexible piezoelectric sensors, contacts for the second detection position with user；Governor circuit module, governor circuit module is arranged in annular body and connect with the first flexible piezoelectric sensors and the second flexible piezoelectric sensors, governor circuit module receives the piezoelectric signal of the first flexible piezoelectric sensors and the output of the second flexible piezoelectric sensors, the pulse wave under the same time shaft of two-way is obtained according to two-way piezoelectric signal, and Pulse-Parameters are obtained according to two-way pulse wave.The present invention uses two-way pulse wave measurement, and accuracy is high, and detection device is easy to carry about with one, it can be achieved that measuring at any time, and can detect blood pressure conditions simultaneously.
Description
Technical field
The application belongs to human health detection field, and in particular to a kind of wearable pulse wave detection device and blood pressure detecting
Method.
Background technique
In medical system, pulse and blood pressure are two very important physiological health parameters, can intuitively detect the heart
Jump state, by examining the heart beat status of survey to understand the basal conditions of patient body.With the development and life matter of medical level
The raising of amount, traditional mercury column type pulse blood pressure instrument is not able to satisfy public demand increasingly in pulses measure, complicated for operation and hold
It easily listens and discerns mistake.And it needs to measure pulse and blood pressure respectively using two kinds of instruments under normal conditions.
With the continuous promotion to instrument demand, pulse detector commonly used in the prior art is usually to be mentioned using photoelectric method
The shortcomings that pulse detector of fetching point pulse information, the pulse detector is: one, photoelectric sphyg belongs to slowly varying faint
Physiological signal can not be accomplished to monitor in real time vulnerable to the interference of ambient noise and limb motion；Two, using single channel pulse wave measurement,
Error is big；Three, equipment is bigger, not portable.Existing common blood pressure pulse wave measurement instrument is usually to pass through to wear cuff and quiet
Sit measurement pulse wave, the blood pressure pulse wave measurement instrument the disadvantage is that: one, be easy by limb motion interference, can not accomplish to supervise in real time
Control；Two, the single channel pulse wave measurement used, error are big；Three, equipment is bigger, not portable.
Summary of the invention
Wearable pulse wave detection device provided by the present application and blood pressure detecting method, it is quasi- using two-way pulse wave measurement
True property is high, and detection device is easy to carry about with one, it can be achieved that measuring at any time, and can detect blood pressure conditions simultaneously.
To achieve the above object, the technical solution that the application is taken are as follows:
A kind of wearable pulse wave detection device, the wearable pulse wave detection device include:
Annular body for wearing；
The inner surface of the annular body is arranged in first flexible piezoelectric sensors, first flexible piezoelectric sensors,
It is contacted for the first detection position with user；
The outer surface of the annular body is arranged in second flexible piezoelectric sensors, second flexible piezoelectric sensors,
It is contacted for the second detection position with user, and the position of the second flexible piezoelectric sensors and first flexible piezoelectric sense
The position of device is corresponding；
Governor circuit module, the governor circuit module are arranged in annular body and sense with first flexible piezoelectric
Device and the connection of the second flexible piezoelectric sensors, the governor circuit module receive first flexible piezoelectric sensors and second soft
Property piezoelectric transducer output piezoelectric signal, the piezoelectric signal according to two-way obtains the pulse wave under the same time shaft of two-way,
And Pulse-Parameters are obtained according to two-way pulse wave.
Preferably, the governor circuit module includes: processing module, and the piezoelectricity mould connected with the processing module
Block, body feeling interaction module and power module；
The processing module includes microcontroller, and the Bluetooth RF circuit connecting with the microcontroller, the indigo plant
The signal that tooth radio circuit is used to receive microcontroller sends two-way pulse wave and/or Pulse-Parameters；
The piezo electric module includes the letter connecting with first flexible piezoelectric sensors and the second flexible piezoelectric sensors
Number processing circuit, the signal processing circuit are used for first flexible piezoelectric sensors and the second flexible piezoelectric sensors are defeated
Piezoelectric signal out is amplified and is filtered, and two-way pulse electric signal transmission is obtained after processing to the microcontroller；
The body feeling interaction module includes linear motor, which connect with the microcontroller, micro- for receiving
The signal of controller generates vibration；
The power module is used to be the processing module, piezo electric module and body feeling interaction module for power supply；
The microcontroller receives the two-way pulse electric signal of piezo electric module output, performs the following operations:
Obtain the pulse wave under the same time shaft of two-way according to two-way pulse electric signal, calculate two-way pulse wave wave crest it
Between time difference TPTTPropagation time as wave；
Enable the spread speed of perfect fluid wave in elastic tube are as follows:
In formula (1), V indicates the spread speed of wave in elastic tube, and Δ x indicates the propagation distance of wave in elastic tube, TPTTTable
Show the propagation time of wave in elastic tube, E indicates that elasticity modulus, h indicate that the wall degree of elastic tube, ρ indicate perfect fluid density, r table
Show the inside radius of elastic tube under equilibrium state；
Enable the relationship between blood vessel elasticity modulus and blood pressure are as follows:
In formula (2), E indicates the blood vessel elasticity modulus under pressure P, i.e. elasticity modulus in formula (1), E0Indicate initial
Elasticity modulus, α are scale parameter；
According to formula (1) and formula (2), the relationship in the propagation time of wave in blood pressure and elastic tube is obtained are as follows:
The relational model in the propagation time for obtaining blood pressure and pulse wave according to formula (3) is as follows:
P=a1lnTPTT+a2 (4)
In formula (4), a1And a2To need the fitting parameter demarcated, so that the propagation time according to pulse wave passes through formula
(4) pressure value is obtained.
Preferably, the annular body is equipped with opening towards the equipment slots on the outside of annular body, the equipment slots and ring
Shape main body is structure as a whole, and the equipment slots are connected with slot cover, and the governor circuit module is located in the equipment slots.
Preferably, the governor circuit module further includes display module, which includes being inlaid in the slot cover
On display screen, the display screen is connect with the microcontroller, for showing two-way pulse wave and/or Pulse-Parameters.
Preferably, the governor circuit module further includes motion module, the motion module includes and the microcontroller
The acceleration transducer of device connection, the acceleration electric signal transmission that the acceleration transducer will test to microcontroller, institute
Acceleration electric signal is stated for correcting for microcontroller to pulse electric signal.
Preferably, the signal processing circuit includes filtering and amplifying circuit and bias amplifier；The amplification filtering
Circuit includes OPA2314 operational amplifier, and the bias amplifier includes TLV6001 operational amplifier；
First flexible piezoelectric sensors or the piezoelectric signal of the second flexible piezoelectric sensors output are transported as OPA2314
Calculate the homophase input of amplifier, reverse phase of the output signal of the TLV6001 operational amplifier as OPA2314 operational amplifier
Input, the output of the OPA2314 operational amplifier are sent to micro-control as pulse electric signal after RC low-pass filter circuit
Device processed.
The application also provides a kind of blood pressure detecting method based on wearable pulse wave detection device, the blood pressure detecting
Method includes:
The pulse wave under the same time shaft of two-way is obtained using wearable pulse wave detection device, calculates two-way pulse wave
Time difference T between wave crestPTTPropagation time as wave；
Enable the spread speed of perfect fluid wave in elastic tube are as follows:
In formula (1), V indicates the spread speed of wave in elastic tube, and Δ x indicates the propagation distance of wave in elastic tube, TPTTTable
Show the propagation time of wave in elastic tube, E indicates that elasticity modulus, h indicate that the wall degree of elastic tube, ρ indicate perfect fluid density, r table
Show the inside radius of elastic tube under equilibrium state；
Enable the relationship between blood vessel elasticity modulus and blood pressure are as follows:
In formula (2), E indicates the blood vessel elasticity modulus under pressure P, i.e. elasticity modulus in formula (1), E0Indicate initial
Elasticity modulus, α are scale parameter；
According to formula (1) and formula (2), the relationship in the propagation time of wave in blood pressure and elastic tube is obtained are as follows:
The relational model in the propagation time for obtaining blood pressure and pulse wave according to formula (3) is as follows:
P=a1lnTPTT+a2 (4)
In formula (4), a1And a2To need the fitting parameter demarcated, so that the propagation time according to pulse wave passes through formula
(4) pressure value is obtained.
Wearable pulse wave detection device provided by the present application and blood pressure detecting method, it is equal in the surfaces externally and internally of annular body
Flexible piezoelectric sensors are set, to acquire the pulse condition of two detection positions of human body simultaneously, two-way pulse wave are obtained, according to right
The processing of two-way pulse wave obtains the higher Pulse-Parameters of accuracy rate；Wearable annular body makes the detection device of the application
It can easily carry with user, be not only convenient for carrying, pick-and-place step can also be avoided to detect at any time to realize；The application is also
Blood pressure parameter can be calculated by two-way pulse wave, measurement while to realize pulse and blood pressure is further simplified user
Use step, improve convenience.
Detailed description of the invention
Fig. 1 is human body artery schematic diagram；
Fig. 2 is the structural schematic diagram of the wearable pulse wave detection device of the application；
Fig. 3 uses schematic diagram for the wearable pulse wave detection device of the application；
Fig. 4 is the structural schematic diagram of the application governor circuit module；
Fig. 5 is the circuit diagram of the application processing module；
Fig. 6 is the circuit diagram of the application filtering and amplifying circuit；
Fig. 7 is the emulation schematic diagram of the cutoff frequency of the application filtering and amplifying circuit；
Fig. 8 is the circuit diagram of the application bias amplifier；
Fig. 9 is first part's circuit diagram of the application power module；
Figure 10 is the second part circuit diagram of the application power module；
Figure 11 is the Part III circuit diagram of the application power module；
Figure 12 is the Part IV circuit diagram of the application power module；
Figure 13 is the Part V circuit diagram of the application power module；
Figure 14 is the circuit diagram of power unit on the application microcontroller；
Figure 15 is the circuit connection schematic diagram of the application acceleration transducer；
Figure 16 is single channel initial pulse wave schematic diagram in embodiment 1；
Figure 17 is the waveform diagram for obtain after Fast Fourier Transform (FFT) and Fast Fourier Transform Inverse to Figure 16；
Figure 18 is the waveform diagram for obtain after the filtering of EMD algorithm to Figure 16；
Figure 19 is in embodiment 1 to the two-way pulse wave schematic diagram obtained after the filtering of two-way initial pulse wave.
In diagram: 1, the second flexible piezoelectric sensors；2, the first flexible piezoelectric sensors；3, body feeling interaction module；4, electric
Source module；5, display screen；6, processing module；7, motion module.
Specific embodiment
Below in conjunction with the attached drawing in the embodiment of the present application, technical solutions in the embodiments of the present application carries out clear, complete
Site preparation description, it is clear that the described embodiments are only a part but not all of the embodiments of the present application.Based on this
Embodiment in application, every other reality obtained by those of ordinary skill in the art without making creative efforts
Example is applied, shall fall in the protection scope of this application.
It should be noted that when component be referred to as with another component " connection " when, it can directly with another component
It connects or there may also be components placed in the middle.Unless otherwise defined, all technical and scientific terms used herein with
The normally understood meaning of those skilled in the art for belonging to the application is identical.Made in the description of the present application herein
It is not to be to limit the application that term, which is only for the purpose of describing specific embodiments,.
A kind of wearable pulse wave detection device of the application, for detecting the pulse wave of two detection positions of user simultaneously
Situation, to obtain the higher Pulse-Parameters of accuracy rate.
As shown in Figure 1, the present embodiment to detect the arteria carotis (position shown in A is at arteria carotis) and oar of user simultaneously
It is further illustrated for pulse wave situation at artery (position shown in B is at arteria carotis) two.
As shown in Fig. 2, in one embodiment, a kind of wearable pulse wave detection device is provided, the wearable pulse wave inspection
Surveying device includes:
Annular body for wearing；
The interior table of the annular body is arranged in first flexible piezoelectric sensors 2, first flexible piezoelectric sensors 2
Face is contacted for the first detection position with user；
The appearance of the annular body is arranged in second flexible piezoelectric sensors 1, second flexible piezoelectric sensors 1
Face is contacted for the second detection position with user, and the position of the second flexible piezoelectric sensors and first flexible piezoelectric
The position of sensor is corresponding；
Governor circuit module, the governor circuit module are arranged in annular body and sense with first flexible piezoelectric
Device 2 connects 1 with the second flexible piezoelectric sensors, and the governor circuit module receives first flexible piezoelectric sensors 2 and the
The piezoelectric signal of two flexible piezoelectric sensors 1 output, the piezoelectric signal according to two-way obtain the arteries and veins under the same time shaft of two-way
It fights wave, and Pulse-Parameters is obtained according to two-way pulse wave.
The present embodiment is using the skin at radial artery as the first detection position, using the skin at arteria carotis as the second detection
Position.Therefore the global shape that the wearable pulse wave detection device of the present embodiment is arranged is Bracelet structure.The Bracelet structure can be real
When be worn on the arm of user, when user needs to carry out pulse detection, examined using detection mode as shown in Figure 3
It surveys, the C in Fig. 3 indicates the wearable pulse wave detection device of the present embodiment of Bracelet structure, is when detecting worn on bracelet
At wrist and the detection of two-way pulse wave is realized in pressing simultaneously in the corresponding site of neck.
Due to the pressing operation of user, the flexible piezoelectric sensors in the present apparatus can be made tightly to be attached to skin surface,
To collect preferably pulse wave signal, more accurate measurement result is obtained.
Position and the first flexibility of the second flexible piezoelectric sensors 1 is arranged in detection while in order to guarantee two-way pulse wave
The position of piezoelectric transducer 2 is corresponding, i.e. the first flexible piezoelectric sensors 2 and the second flexible piezoelectric sensors 1 are located at bracelet
The same area, and it is in the surfaces externally and internally in the region, the first, second flexible piezoelectric sensors can be simultaneously when guaranteeing pressing operation
Work.
Further, governor circuit module can be dispersion and bury inside annular body, is also possible to concentrated setting and exists
At the one of annular body.In one embodiment, annular body is equipped with opening towards the equipment slots on the outside of annular body, the equipment
Slot is structure as a whole with annular body, and the equipment slots are connected with slot cover, and the governor circuit module is located in the equipment slots.
Governor circuit module concentrated setting is convenient for circuit configuration and heat dissipation in equipment slots, and equipment slots and slot cover can be with
It is integral structure to improve the protection to governor circuit module, may be a detachable connection structure in order to later maintenance.
As shown in figure 4, in one embodiment, governor circuit module includes: processing module 6, and with the processing module 6
Piezo electric module, body feeling interaction module 3 and the power module 4 of connection.
The processing module 6 of governor circuit module includes microcontroller, and the Bluetooth RF connecting with the microcontroller
Circuit, the signal that the Bluetooth RF circuit is used to receive microcontroller send two-way pulse wave and/or Pulse-Parameters.
In one embodiment, Bluetooth RF circuit is circumscribed with device end, carries out data by Bluetooth protocol between the two
Transmission, device end receive the two-way pulse wave and/or Pulse-Parameters that Bluetooth RF circuit is sent, for two-way pulse wave
And/or Pulse-Parameters are further analyzed or are shown.And the device end can be smart phone, be also possible to computer etc..
Specifically, the circuit diagram of processing module 6 is as shown in figure 5, in the present embodiment, microcontroller is using integrated
The MCU (microcontroller) of BLE function, analog-digital conversion function, and the model CC2640R2FRSM of microcontroller.
The Bluetooth RF circuit being connected with microcontroller includes Bluetooth chip, in the present embodiment, the model of Bluetooth chip
Balun/LFB182G45BG5D920, the RF_N pin of microcontroller and the BP1 pin of Bluetooth chip connect, microcontroller
The connection of the BP2 pin of RF_P pin and Bluetooth chip uploads pulse wave and/or pulse to device end for controlling Bluetooth chip
Parameter.
The piezo electric module of governor circuit module includes connecting with the first flexible piezoelectric sensors and the second flexible piezoelectric sensors
The signal processing circuit connect, the signal processing circuit are used to pass first flexible piezoelectric sensors and the second flexible piezoelectric
The piezoelectric signal of sensor output is amplified and is filtered, and two-way pulse electric signal transmission is obtained after processing to microcontroller.
The high pulse data of accuracy in order to obtain, in one embodiment, signal processing circuit include filtering and amplifying circuit
And bias amplifier；The filtering and amplifying circuit includes OPA2314 operational amplifier, and the bias amplifier includes
TLV6001 operational amplifier.
In signal conversion process, the first flexible piezoelectric sensors or the piezoelectricity of the second flexible piezoelectric sensors output are utilized
Homophase input of the signal as OPA2314 operational amplifier, the output signal conduct of the TLV6001 operational amplifier
The output of the anti-phase input of OPA2314 operational amplifier, the OPA2314 operational amplifier is made after RC low-pass filter circuit
Microcontroller is sent to for pulse electric signal.
Specifically, as shown in fig. 6, filtering and amplifying circuit uses OPA2314 operational amplifier, mainly by collected pressure
Electric signal amplifies.It is connected with resistance R25 between the output end and inverting input terminal of OPA2314 operational amplifier, reverse phase is defeated
Enter end and be connected with resistance R24, the other end and TLV6001 operational amplifier of resistance R24, non-inverting input terminal connection arranges the 2 of needle J21
Number stitch, the output of the first flexible piezoelectric sensors or the second flexible piezoelectric sensors are input to homophase input by No. 2 stitch
End, and non-inverting input terminal is grounded by resistance R23, No. 1 stitch of row needle J2 is connected to the ground terminal of resistance R23, OPA2314 fortune
The output end for calculating amplifier connects resistance R26, and the other end of resistance R24 connects microcontroller, and the other end of resistance R24 leads to simultaneously
Cross capacitor C23 ground connection.
The amplification factor of filtering and amplifying circuit is determined by the ratio of R25 and R24, amplification factor=R25/R24=
10.10 times of amplification is obtained according to experiment to meet the requirements.The effect of C24 of OPA2314 operational amplifier power input connection is
It filters high frequency and pressure stabilizing is carried out to power supply.R26 and C23 collectively forms a RC low-pass filter circuit, and the frequency of human pulse is generally low
In 30Hz, so 40Hz or so should be arranged in RC frequency.
As shown in fig. 7, using the cutoff frequency of 39k Ω resistance and the low-pass filter circuit of 100nF capacitor by emulating
Its practical cutoff frequency are as follows: 40.65Hz.Therefore the resistance value of R26 is 39K Ω in the present embodiment, the capacitance of C23 is 100nF.
As shown in figure 8, bias amplifier uses TLV6001 operational amplifier.TLV6001 operational amplifier it is same mutually defeated
Enter to terminate the slide plate of adjustable resistance RJ1, a binding post of adjustable resistance RJ1 meets 3V by resistance R22, and adjustable resistance RJ1's is another
One binding post meets -3V by resistance R21；Inverting input terminal and output end are commonly connected to the resistance R7 in filtering and amplifying circuit.
The C21 and C22 of TLV6001 operational amplifier positive and negative anodes connection are respectively that 100nF can carry out pressure stabilizing and filtering to power supply, are filtered out
High-frequency noise.
Bias amplifier biases piezoelectric signal, and ambipolar piezoelectric signal is converted into unipolar pressure
Electric signal, it is ensured that piezoelectric signal is in the position for being suitble to analysis.R22, R21 and RJ1 in bias amplifier are collectively formed can
Bleeder circuit is adjusted, amplifier homophase input is adjusted.
In one embodiment, the resistance value of resistance R22, R21 selects 100K Ω, in order to limit amplifier input current
System divides adjustable range are as follows:
In the present embodiment, the first flexible piezoelectric sensors and the second flexible piezoelectric sensors are connected separately with independent signal
Processing circuit, two-way piezoelectric signal is amplified, filter and bias treatment after, obtained two-way pulse electric signal (is used all the way
PIEZO is indicated, is indicated all the way with INTB) in, it is input to the DIO_7 pin of microcontroller all the way, another way is input to microcontroller
The DIO_8 pin of device.
And display and upload process are carried out for the ease of pulse electric signal, microcontroller is using ADC module acquisition input
Two-way pulse electric signal obtains two groups of waveform discrete datas corresponding with pulse electric signal, and according to time shaft that waveform is discrete
Pulse wave is obtained after data connection, while Pulse-Parameters are calculated.
In one embodiment, when microcontroller calculates Pulse-Parameters, the two-way pulse electric signal of piezo electric module output is received,
It performs the following operations:
Obtain the pulse wave under the same time shaft of two-way according to two-way pulse electric signal, calculate two-way pulse wave wave crest it
Between time difference TPTTPropagation time as wave；
Enable the spread speed of perfect fluid wave in elastic tube are as follows:
In formula (1), V indicates the spread speed of wave in elastic tube, and Δ x indicates the propagation distance of wave in elastic tube, TPTTTable
Show the propagation time of wave in elastic tube, E indicates that elasticity modulus, h indicate that the wall degree of elastic tube, ρ indicate perfect fluid density, r table
Show the inside radius of elastic tube under equilibrium state；
Enable the relationship between blood vessel elasticity modulus and blood pressure are as follows:
In formula (2), E indicates the blood vessel elasticity modulus under pressure P, i.e. elasticity modulus in formula (1), E0Indicate initial
Elasticity modulus, α are scale parameter.
According to formula (1) and formula (2), the relationship in the propagation time of wave in blood pressure and elastic tube is obtained are as follows:
The relational model in the propagation time for obtaining blood pressure and pulse wave according to formula (3) is as follows:
P=a1lnTPTT+a2 (4)
In formula (4), a1And a2To need the fitting parameter demarcated, so that the propagation time according to pulse wave passes through formula
(4) pressure value is obtained.
It should be noted that Pulse-Parameters are not limited only to the propagation time of wave, blood pressure, ginseng needed for can also be heart rate etc.
Number, therefore other parameters can also be calculated according to two groups of pulse waves in microcontroller.Such as when calculating heart rate, according to two groups of pulses
Wave obtains the number of wave crest or trough in certain time, so that conversion obtains heart rate value.
The body feeling interaction module 3 of governor circuit module includes linear motor, which connect with the microcontroller,
Signal for receiving microcontroller generates vibration.
Microcontroller judges whether collected signal is normal after receiving pulse electric signal, when then acquisition is default if normal
Between (such as 30s) the linear motor vibrations of rear-guard, it is completed with prompting user to acquire；If the signal of acquisition is abnormal, persistently adopt
Collection is until acquire enough data.Linear motor uses the linear electric machine of the direction ELV1411A X- vibration in the present embodiment.
The linear electric machine of the direction ELV1411A X- vibration carries driving chip, and the driving chip and MCU pass through I2C bus communication.
The power module 4 of governor circuit module is used to power for microcontroller.It should be noted that power module is mainly
Microcontroller power supply, while may be the power supply such as peripheral hardware, such as Bluetooth RF circuit, piezo electric module of microcontroller.Power supply
Module includes battery and power circuit, and wherein battery can be rechargeable battery.
If Fig. 9~Figure 13 show the circuit diagram of power module, exported respectively using 3 TPS78230DDCR
The voltage of 3.3V, 3V and 1.8V, and suitable supply voltage is provided to each element by component requirements.
The metal-oxide-semiconductor for a piece of TPS78230DDCR output end wherein connecting with operational amplifier is connected to microcontroller
DIO_4 pin stops power supply when idle and carries out power consumption control in order to control whether to power to operational amplifier.
When needing to turn off, the MOSG pin (DIO_4 pin) of microcontroller exports high level, and metal-oxide-semiconductor is not turned on, that is, stops to operation
Amplifier power supply；When needing to open, MOSG pin exports low level, and metal-oxide-semiconductor conducting powers to operational amplifier.R02 resistance
For pull-up resistor, resistance value comprehensively considers according to its switching speed of guarantee and pull-up, and metal-oxide-semiconductor is made usually to be in high level, turns off
State.
- 3V in power module is converted by negative voltage transition device LTC1983-3, and composition dual power supply is supplied to operational amplifier
Electricity.SHDN pin on LTC1983-3 carries out power consumption control whether can control the shutdown of LTC1983-3.The electricity being connected with power supply
Appearance is voltage regulation filtering effect.
J01 in power module is external connection battery pin, is the power supply primary source of entire detection device, and Q1 is p-type MOS
Pipe play the role of it is anti-reverse, when just connecing, metal-oxide-semiconductor grid be low level, metal-oxide-semiconductor conducting.When battery plus-negative plate reversal connection, grid
For high level, metal-oxide-semiconductor is not turned on, and does not give system energization.
It as shown in figure 14, is the circuit of power unit on microcontroller, wherein DCDCSW is chip interior DC decompression mould
Block, inductance size are 10Uh, filter capacitor 10uF, 100nF, 100nF, and prime filter capacitor uses 10uF, low for filtering
Frequently, output ripple and low-frequency disturbance are reduced, the capacitor of 100nF, which is used to reduce the high frequency as caused by load current transient change, to be done
It disturbs, pressure stabilization function can also be played.
3.3V is the voltage of power module output, and VDDS connects VDDS, VDDS2, VDDS_DCDC pin of microcontroller, magnetic
Pearl is used to inhibit noise, and the selection of magnetic bead need to use 1k magnetic bead in the present embodiment according to actual effect；Filter capacitor is respectively
100nF、1000nF、10μF、100nF。
In one embodiment, in order to improve the Man machine interaction of this detection device, governor circuit module further includes display
Module, the display module include the display screen 5 being inlaid in the slot cover, and the display screen is connect with the microcontroller, are used
In display two-way pulse wave and/or Pulse-Parameters.Display can be OLED or LED etc..
It, during the inspection process may trembling because of user since the pulse wave detection device of the present embodiment is Bracelet structure
Dynamic or displacement causes measurement result inaccurate, and in order to avoid above situation, in one embodiment, governor circuit module further includes fortune
Dynamic model block 7, the motion module 7 include the acceleration transducer connecting with the microcontroller, and the acceleration transducer will
The acceleration electric signal transmission detected to microcontroller, the acceleration electric signal is used for for microcontroller to pulse electric signal
It is corrected.
Since people's movement will cause flexible piezoelectric sensors deformation, while pulse electric signal being caused catastrophe point occur, and added
The acceleration electric signal that velocity sensor measures can compensate catastrophe point to correct the catastrophe point of pulse electric signal.
Specifically, as shown in figure 15, the model BMA250E of acceleration transducer.
The INT1 pin of chip BMA250E connects the DIO_3 pin of microcontroller, and the SDA pin of chip BMA250E connects micro-control
The SCL pin of the DIO_6 pin of device processed, chip BMA250E connects the DIO_5 pin of microcontroller, to realize microcontroller to adding
The control of velocity sensor simultaneously obtains acceleration electric signal.
In order to improve the accuracy of testing result, after microcontroller receives the pulse electric signal of signal processing circuit,
Algorithm filtering further will be carried out to waveform discrete data, and further illustrate the application to waveform dispersion number by the following examples
According to the process flow for carrying out algorithm filtering.
It should be noted that listing the model or value of element in each module in the present embodiment, it is only used as a kind of implementation
The reference of scheme, the member not as the limitation to each module, i.e., under the premise of guaranteeing that each module realizes correlation function, in module
Part can be replaced.
Embodiment 1
As shown in figure 16, for obtained initial pulse wave after the connection of single channel waveform discrete data, to initial pulse wave into
Row Fast Fourier Transform (FFT) determines that industrial frequency noise is 50Hz, line frequency domain zero noise reduction process of going forward side by side.Since pulse frequency exists
Between 0.4Hz to 8Hz, so carrying out frequency domain filtering, 0~0.4Hz and the frequency domain greater than 8Hz are down to zero, and carry out fast
Fast Fourier inversion obtains filtered signal, as shown in figure 17.
It should be noted that filtering algorithm is not limited to using the above method, small wave converting method is can also be used in filtering algorithm,
Or with the progress of EMD algorithm.It is as shown in figure 18 gained after being filtered using EMD algorithm to the initial pulse wave in Figure 11
Signal.
The filtering to two-way initial pulse wave is realized based on the above-mentioned filtering operation to single channel initial pulse wave, after filtering
The two-way pulse wave arrived is as shown in figure 19, and two-way pulse wave can be used for obtaining relevant Pulse-Parameters, such as the two-way in Figure 19
Time difference PTT (i.e. T between two wave crest of pulse wavePTT) it can be used as propagation time of pulse wave.
It should be noted that the present embodiment focuses on showing the process and effect of algorithm filtering, the tool of attached drawing medium wave
Volume data is unrestricted, therefore omits the dependent coordinate axis in waveform diagram.
In one embodiment, a kind of blood pressure detecting method, wearable pulse of the detection method based on the application are also provided
Wave detection device.Specifically, the blood pressure detecting method includes:
The pulse wave under the same time shaft of two-way is obtained using wearable pulse wave detection device, calculates two-way pulse wave
Time difference T between wave crestPTTPropagation time as wave；
Enable the spread speed of perfect fluid wave in elastic tube are as follows:
In formula (1), V indicates the spread speed of wave in elastic tube, and Δ x indicates the propagation distance of wave in elastic tube, TPTTTable
Show the propagation time of wave in elastic tube, E indicates that elasticity modulus, h indicate that the wall degree of elastic tube, ρ indicate perfect fluid density, r table
Show the inside radius of elastic tube under equilibrium state；
Enable the relationship between blood vessel elasticity modulus and blood pressure are as follows:
In formula (2), E indicates the blood vessel elasticity modulus under pressure P, i.e. elasticity modulus in formula (1), E0Indicate initial
Elasticity modulus, α are scale parameter.
According to formula (1) and formula (2), the relationship in the propagation time of wave in blood pressure and elastic tube is obtained are as follows:
Assuming that arterial blood tube wall is perfect elasticity pipe, blood is perfect fluid, and ignores blood viscosity, density etc. no
The influence of Parameters variation can be measured, then the relational model in the propagation time for obtaining blood pressure and pulse wave according to formula (3) is as follows:
P=a1lnTPTT+a2 (4)
In formula (4), a1And a2To need the fitting parameter demarcated, so that the propagation time according to pulse wave passes through formula
(4) pressure value is obtained.
In another embodiment, it is also possible that according to the method that two-way pulse wave obtains blood pressure using neural network, with filter
Input of the pulse wave acquisition characteristics point as neural network after wave, and to measure blood pressure data as output label, by big
Label data training neural network is measured, to obtain nonlinear regression blood pressure values algorithm.
Wearable pulse wave detection device provided in this embodiment and blood pressure detecting method, in the surfaces externally and internally of annular body
Flexible piezoelectric sensors are respectively provided with, to acquire the pulse condition of two detection positions of human body simultaneously, obtain two-way pulse wave, according to
The higher Pulse-Parameters of accuracy rate are obtained to the processing of two-way pulse wave；Wearable annular body fills the detection of the application
Setting easily to carry with user, be not only convenient for carrying, and pick-and-place step can also be avoided to detect at any time to realize；The application
Blood pressure parameter can also be calculated by two-way pulse wave, measurement while to realize pulse and blood pressure is further simplified use
The use step at family improves convenience.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not present
Contradiction all should be considered as described in this specification.
The several embodiments of the application above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the concept of this application, various modifications and improvements can be made, these belong to the protection of the application
Range.Therefore, the scope of protection shall be subject to the appended claims for the application patent.
Claims (7)
1. a kind of wearable pulse wave detection device, which is characterized in that the wearable pulse wave detection device includes:
Annular body for wearing；
First flexible piezoelectric sensors, first flexible piezoelectric sensors are arranged in the inner surface of the annular body, are used for
It is contacted with the first detection position of user；
Second flexible piezoelectric sensors, second flexible piezoelectric sensors are arranged in the outer surface of the annular body, are used for
It is contacted with the second detection position of user, and the position of the second flexible piezoelectric sensors and first flexible piezoelectric sensors
Position is corresponding；
Governor circuit module, the governor circuit module be arranged in annular body and with first flexible piezoelectric sensors and
The connection of second flexible piezoelectric sensors, the governor circuit module receive first flexible piezoelectric sensors and the second flexible pressure
The piezoelectric signal of electric transducer output, the piezoelectric signal according to two-way obtain the pulse wave under the same time shaft of two-way, and root
Pulse-Parameters are obtained according to two-way pulse wave.
2. wearable pulse wave detection device as described in claim 1, which is characterized in that the governor circuit module includes:
Processing module, and the piezo electric module, body feeling interaction module and the power module that are connected with the processing module；
The processing module includes microcontroller, and the Bluetooth RF circuit connecting with the microcontroller, the bluetooth are penetrated
The signal that frequency circuit is used to receive microcontroller sends two-way pulse wave and/or Pulse-Parameters；
The piezo electric module includes at the signal connecting with first flexible piezoelectric sensors and the second flexible piezoelectric sensors
Circuit is managed, what the signal processing circuit was used to export first flexible piezoelectric sensors and the second flexible piezoelectric sensors
Piezoelectric signal is amplified and is filtered, and two-way pulse electric signal transmission is obtained after processing to the microcontroller；
The body feeling interaction module includes linear motor, which connect with the microcontroller, for receiving microcontroller
The signal of device generates vibration；
The power module is used to be the processing module, piezo electric module and body feeling interaction module for power supply；
The microcontroller receives the two-way pulse electric signal of piezo electric module output, performs the following operations:
The pulse wave under the same time shaft of two-way is obtained according to two-way pulse electric signal, between the wave crest for calculating two-way pulse wave
Time difference TPTTPropagation time as wave；
Enable the spread speed of perfect fluid wave in elastic tube are as follows:
In formula (1), V indicates the spread speed of wave in elastic tube, and Δ x indicates the propagation distance of wave in elastic tube, TPTTIndicate bullet
Property pipe in wave propagation time, E indicates that elasticity modulus, h indicate that the wall degree of elastic tube, ρ indicate perfect fluid density, and r indicates flat
The inside radius of elastic tube under weighing apparatus state；
Enable the relationship between blood vessel elasticity modulus and blood pressure are as follows:
E=E0eαP (2)
In formula (2), E indicates the blood vessel elasticity modulus under pressure P, i.e. elasticity modulus in formula (1), E0Indicate initial elasticity
Modulus, α are scale parameter；
According to formula (1) and formula (2), the relationship in the propagation time of wave in blood pressure and elastic tube is obtained are as follows:
The relational model in the propagation time for obtaining blood pressure and pulse wave according to formula (3) is as follows:
P=a1lnTPTT+a2 (4)
In formula (4), a1And a2To need the fitting parameter demarcated, to be obtained according to the propagation time of pulse wave by formula (4)
To pressure value.
3. wearable pulse wave detection device as claimed in claim 2, which is characterized in that the annular body is equipped with opening
Towards the equipment slots on the outside of annular body, which is structure as a whole with annular body, and the equipment slots are connected with slot cover, institute
Governor circuit module is stated to be located in the equipment slots.
4. wearable pulse wave detection device as claimed in claim 3, which is characterized in that the governor circuit module further includes
Display module, the display module include the display screen being inlaid in the slot cover, and the display screen is connect with the microcontroller,
For showing two-way pulse wave and/or Pulse-Parameters.
5. wearable pulse wave detection device as claimed in claim 2, which is characterized in that the governor circuit module further includes
Motion module, the motion module include the acceleration transducer connecting with the microcontroller, and the acceleration transducer will
The acceleration electric signal transmission detected to microcontroller, the acceleration electric signal is used for for microcontroller to pulse electric signal
It is corrected.
6. wearable pulse wave detection device as claimed in claim 2, which is characterized in that the signal processing circuit includes putting
Big filter circuit and bias amplifier；The filtering and amplifying circuit includes OPA2314 operational amplifier, the biasing amplification electricity
Road includes TLV6001 operational amplifier；
First flexible piezoelectric sensors or the piezoelectric signal of the second flexible piezoelectric sensors output are put as OPA2314 operation
The homophase input of big device, the output signal of the TLV6001 operational amplifier are defeated as the reverse phase of OPA2314 operational amplifier
Enter, the output of the OPA2314 operational amplifier is sent to microcontroller as pulse electric signal after RC low-pass filter circuit
Device.
7. a kind of blood pressure detecting method based on wearable pulse wave detection device described in claim 1, which is characterized in that institute
The blood pressure detecting method stated includes:
The pulse wave under the same time shaft of two-way is obtained using wearable pulse wave detection device, calculates the wave crest of two-way pulse wave
Between time difference TPTTPropagation time as wave；
Enable the spread speed of perfect fluid wave in elastic tube are as follows:
In formula (1), V indicates the spread speed of wave in elastic tube, and Δ x indicates the propagation distance of wave in elastic tube, TPTTIndicate bullet
Property pipe in wave propagation time, E indicates that elasticity modulus, h indicate that the wall degree of elastic tube, ρ indicate perfect fluid density, and r indicates flat
The inside radius of elastic tube under weighing apparatus state；
Enable the relationship between blood vessel elasticity modulus and blood pressure are as follows:
E=E0eαP (2)
In formula (2), E indicates the blood vessel elasticity modulus under pressure P, i.e. elasticity modulus in formula (1), E0Indicate initial elasticity
Modulus, α are scale parameter；
According to formula (1) and formula (2), the relationship in the propagation time of wave in blood pressure and elastic tube is obtained are as follows:
The relational model in the propagation time for obtaining blood pressure and pulse wave according to formula (3) is as follows:
P=a1lnTPTT+a2 (4)
In formula (4), a1And a2To need the fitting parameter demarcated, to be obtained according to the propagation time of pulse wave by formula (4)
To pressure value.
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Cited By (3)
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| CN110897618A (en) * | 2019-12-12 | 2020-03-24 | 中国科学院深圳先进技术研究院 | Pulse wave conduction calculation method and device and terminal equipment |
| CN112891728A (en) * | 2021-02-26 | 2021-06-04 | 佛山科学技术学院 | Self-adaptive control blood pump supply system and method |
| WO2024066076A1 (en) * | 2022-09-29 | 2024-04-04 | 汉王科技股份有限公司 | Blood pressure detection method and device, blood pressure gauge, and medium |
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