CN110296970A - Portable blood sugar measuring instrument - Google Patents
Portable blood sugar measuring instrument Download PDFInfo
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- CN110296970A CN110296970A CN201910711609.2A CN201910711609A CN110296970A CN 110296970 A CN110296970 A CN 110296970A CN 201910711609 A CN201910711609 A CN 201910711609A CN 110296970 A CN110296970 A CN 110296970A
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- 239000008280 blood Substances 0.000 title claims abstract description 156
- 210000004369 blood Anatomy 0.000 title claims abstract description 156
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 124
- 239000008103 glucose Substances 0.000 claims abstract description 124
- 238000001514 detection method Methods 0.000 claims abstract description 74
- 230000003287 optical effect Effects 0.000 claims abstract description 63
- 239000013307 optical fiber Substances 0.000 claims abstract description 41
- 238000012360 testing method Methods 0.000 claims abstract description 32
- 206010033675 panniculitis Diseases 0.000 claims abstract description 22
- 210000004304 subcutaneous tissue Anatomy 0.000 claims abstract description 21
- 239000007788 liquid Substances 0.000 claims abstract description 16
- 238000006243 chemical reaction Methods 0.000 claims description 52
- 238000012545 processing Methods 0.000 claims description 49
- 238000001228 spectrum Methods 0.000 claims description 29
- 238000004891 communication Methods 0.000 claims description 25
- 238000005259 measurement Methods 0.000 claims description 23
- 239000000523 sample Substances 0.000 claims description 13
- 239000012528 membrane Substances 0.000 claims description 11
- 239000000835 fiber Substances 0.000 claims description 10
- 239000011248 coating agent Substances 0.000 claims description 4
- 238000000576 coating method Methods 0.000 claims description 4
- 208000033748 Device issues Diseases 0.000 claims description 3
- 230000003993 interaction Effects 0.000 claims description 3
- 230000019491 signal transduction Effects 0.000 claims description 3
- 230000011514 reflex Effects 0.000 claims description 2
- 230000005622 photoelectricity Effects 0.000 claims 1
- 238000010586 diagram Methods 0.000 description 12
- 230000005611 electricity Effects 0.000 description 5
- 241000219095 Vitis Species 0.000 description 4
- 235000009754 Vitis X bourquina Nutrition 0.000 description 4
- 235000012333 Vitis X labruscana Nutrition 0.000 description 4
- 235000014787 Vitis vinifera Nutrition 0.000 description 4
- 238000007689 inspection Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000004737 colorimetric analysis Methods 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002848 electrochemical method Methods 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000000352 storage cell Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The invention discloses a kind of portable blood sugar measuring instruments, one end of glucose-sensitive optical fiber can be directly placed in subcutaneous tissue liquid by the portable blood sugar measuring instrument, emit detection optical signal by blood sugar test component, and make the other end incident glucose-sensitive optical fiber of a part of detection optical signal by the glucose-sensitive optical fiber, to obtain fluorescence feedback signal, blood sugar test component detects the fluorescence feedback signal and obtains the first electric signal, detects the second telecommunications of detection light signal acquisition described in another part.Blood glucose value can be calculated according to first electric signal and second electric signal.As it can be seen that can be directly based upon first electric signal after technical solution of the present invention is calibrated before factory or after user's self calibration and second electric signal carries out blood glucose value detection, it is easy to operate, it is easy to use.
Description
Technical field
The present invention relates to the field of medical instrument technology, more specifically, being related to a kind of portable blood sugar measuring instrument.
Background technique
Blood sugar for human body value is an important parameter for reacting human health status.Blood glucose value is detected in physical examination, disease detection
Or special population (such as diabetes patient) blood Sugar Monitoring etc., play an important role.
Currently, the home-use blood glucose measuring device of mainstream requires to acquire user by blood collecting pen or blood sampling test paper in the market
Subcutis liquid carries out blood glucose value detection by the methods of colorimetric method, electrochemical method or photometer detection in vitro.
As it can be seen that existing home-use blood glucose measuring device needs blood was collected first to sample, the inspection of blood glucose value is carried out in vitro
It surveys, it is complicated for operation, it is not convenient to use.
Summary of the invention
In view of this, technical solution of the present invention provides a kind of portable blood sugar measuring instrument, without blood was collected sampling, behaviour
Make simply, to be easy to use.
To achieve the goals above, the invention provides the following technical scheme:
A kind of portable blood sugar measuring instrument, the portable blood sugar measuring instrument include:
Blood sugar test component, the blood sugar test component believe a part of detection light for being emitted detection optical signal
Number the fluorescence feedback signal to subcutaneous tissue liquid is detected to obtain fluorescence feedback signal by glucose-sensitive fiber optic conduction
The first electric signal is obtained, the second telecommunications of detection light signal acquisition described in another part is detected；First electric signal and described
Second electric signal is for calculating blood glucose value；
Shell, the blood sugar test component are mounted in the shell；There is light to receive and dispatch window, institute on the surface of the shell
It states light transmitting-receiving window to be used to provide part the detection optical signal for the glucose-sensitive optical fiber, be also used to through the grape
Glucose sensitive optical fiber obtains the fluorescence feedback signal.
Preferably, in above-mentioned portable blood sugar measuring instrument, the shell includes: the front cover and rear cover mutually fastened；
Wherein, the front cover and the rear cover form a chamber after fastening, and the blood sugar test component is mounted on the chamber
It is indoor；The rear cover is provided with the light transmitting-receiving window.
Preferably, in above-mentioned portable blood sugar measuring instrument, further includes: setting deviates from the front cover side in the rear cover
Maintaining member；
Wherein, when carrying out blood glucose measurement, the maintaining member is used for the shell is opposite with user's skin surface solid
It is fixed.
Preferably, in above-mentioned portable blood sugar measuring instrument, the rear cap surface has groove, and the bottom of the groove is set
It is equipped with the light transmitting-receiving window；
The maintaining member has for fixed convex portion in the groove, and the convex portion corresponds to the light
The position of window is received and dispatched with the through-hole for fixing the glucose-sensitive optical fiber.
Preferably, in above-mentioned portable blood sugar measuring instrument, light-guiding pillar, the light-guiding pillar and institute are installed in the chamber
Light transmitting-receiving window face setting is stated, the light-guiding pillar is used for the part detection optical signal for being emitted the blood sugar test component
Conduction conducts the fluorescence feedback signal of the glucose-sensitive fiber exit to described to the glucose-sensitive optical fiber
Blood sugar test component.
Preferably, in above-mentioned portable blood sugar measuring instrument, glucose-sensitive optical fiber one end is used to receive with the light
Hair window is relatively fixed, and to receive a part of light detecting signal of the blood sugar test component output, the other end, which has, to be used
In the probe for being placed in subcutaneous tissue；
Wherein, the probe has the end of probe for being placed in subcutaneous tissue, and the length of the end of probe is 4mm-
5mm。
Preferably, in above-mentioned portable blood sugar measuring instrument, the blood sugar test component includes:
Light source device, the light source device is for emitting the detection optical signal；
Spectrum groupware, the spectrum groupware are used to the detection optical signal being divided into two parts, a part of detection light
Signal is by the glucose-sensitive fiber optic conduction to subcutaneous tissue liquid, to obtain fluorescence feedback signal；
First photoelectric conversion processing circuit, the first photoelectric conversion processing circuit are used to pass through the glucose-sensitive light
Fibre detects the fluorescence feedback signal, generates the first electric signal；
Second photoelectric conversion processing circuit, the second photoelectric conversion processing circuit is for detecting detection described in another part
Optical signal generates the second electric signal.
Preferably, in above-mentioned portable blood sugar measuring instrument, the spectrum groupware includes:
Prism group, the prism group include the first prism and the second prism of opposite fitting；
Positioned at the semi-permeable membrane of first prism and the opposite coating surface of second prism, the semi-permeable membrane is used for institute
The detection optical signal for stating light source device transmitting is divided into two parts, so that a part of detection optical signal is quick by the glucose
Photosensitive fine incident subcutaneous tissue liquid, forms fluorescence feedback signal, so that detection optical signal incidence described second described in another part
Photoelectric conversion processing circuit；
Wherein, the fluorescence feedback signal passes through the incident prism group of the glucose-sensitive fiber optic conduction, part institute
It states fluorescence feedback signal and the first photoelectric conversion processing circuit is reflexed to by the semi-permeable membrane.
Preferably, in above-mentioned portable blood sugar measuring instrument, the blood sugar test component further include:
MCU, the MCU and the first photoelectric conversion processing circuit and the second photoelectric conversion processing circuit connect
It connects, for calculating blood glucose value according to first electric signal and second electric signal.
Preferably, in above-mentioned portable blood sugar measuring instrument, further includes: wireless communication module, the wireless communication module
For carrying out data interaction with terminal device；
Wherein, the wireless communication module is used for at least one performed the following operations: the blood glucose value is sent to institute
It states terminal device to be shown, or receives control instruction that the terminal device issues or by first electric signal and described
Second electric signal is sent to the terminal device, so that the terminal device is based on first electric signal and described second
Electric signal calculates the blood glucose value, and shows the blood glucose value.
It as can be seen from the above description, can be directly by Portugal in the portable blood sugar measuring instrument that technical solution of the present invention provides
One end of grape glucose sensitive optical fiber is placed in subcutaneous tissue liquid, emits detection optical signal by blood sugar test component, and make one
Divide the other end incident glucose-sensitive optical fiber of the detection optical signal by the glucose-sensitive optical fiber, it is glimmering to obtain
Optical feedback signal, blood sugar test component detect the fluorescence feedback signal and obtain the first electric signal, detect and examine described in another part
Light signal obtains the second telecommunications.Blood glucose value can be calculated according to first electric signal and second electric signal.It can
See, after technical solution of the present invention is calibrated before factory or after user's self calibration, first electric signal can be directly based upon
And second electric signal carries out blood glucose value detection, and it is easy to operate, it is easy to use.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
The embodiment of invention for those of ordinary skill in the art without creative efforts, can also basis
The attached drawing of offer obtains other attached drawings.
Fig. 1 is a kind of sectional drawing of portable blood sugar measuring instrument provided in an embodiment of the present invention；
Fig. 2 is the front plan view of portable blood sugar measuring instrument shown in Fig. 1；
Fig. 3 is the back side top view of portable blood sugar measuring instrument shown in Fig. 1；
Fig. 4 is another sectional drawing of portable blood sugar measuring instrument shown in Fig. 1；
Fig. 5 is a kind of structural schematic diagram of maintaining member provided in an embodiment of the present invention；
Fig. 6 is that a kind of shell for taking formula glucometer provided in an embodiment of the present invention and maintaining member assemble principle signal
Figure；
Fig. 7 is a kind of top view for taking formula glucometer with maintaining member provided in an embodiment of the present invention；
Fig. 8 is a kind of structural schematic diagram of blood glucose measurement component provided in an embodiment of the present invention；
Fig. 9 is the structural schematic diagram of another blood glucose measurement component provided in an embodiment of the present invention；
Figure 10 is the structural schematic diagram of another blood glucose measurement component provided in an embodiment of the present invention；
Figure 11 is the structural schematic diagram of another blood glucose measurement component provided in an embodiment of the present invention；
Figure 12 is the structural schematic diagram of another blood glucose measurement component provided in an embodiment of the present invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, with reference to the accompanying drawing and specific real
Applying mode, the present invention is described in further detail.
With reference to Fig. 1-Fig. 3, Fig. 1 is a kind of sectional drawing of portable blood sugar measuring instrument provided in an embodiment of the present invention, and Fig. 2 is
The front plan view of portable blood sugar measuring instrument shown in Fig. 1, Fig. 3 are the back side top view of portable blood sugar measuring instrument shown in Fig. 1,
The portable blood sugar measuring instrument includes: blood sugar test component 102 and shell 101.
A part of detection optical signal is passed through grape for being emitted detection optical signal by the blood sugar test component 102
Glucose sensitive fiber optic conduction detects the fluorescence feedback signal and obtains the first electricity to subcutaneous tissue liquid to obtain fluorescence feedback signal
Signal detects the second telecommunications of detection light signal acquisition described in another part；First electric signal and second electric signal
For calculating blood glucose value；The blood sugar test component 102 is mounted in the shell 101.Before the glucose-sensitive optical fiber is
End face has the optical fiber of blood glucose sensitive fluorescence material coating, and the blood glucose sensitive fluorescence material is the phosphor of conventional detection blood glucose
Material, the application are not specifically limited its specific type.
There is light to receive and dispatch window 103 on the surface of the shell 101, and the light transmitting-receiving window 103 is used to be the glucose
Sensitive optical fibre provides the part detection optical signal and also uses in order to generate the fluorescence feedback signal in subcutaneous tissue liquid
In obtaining the fluorescence feedback signal by the glucose-sensitive optical fiber, in order to which the blood sugar test component 102 detects institute
Fluorescence feedback signal is stated, first electric signal is generated.The glucose-sensitive optical fiber is not shown in Fig. 1-Fig. 3.The section of Fig. 1
Perpendicular to the axial direction of light transmitting-receiving window 103.
With reference to Fig. 4, Fig. 4 is another sectional drawing of portable blood sugar measuring instrument shown in Fig. 1, and the section of the sectional drawing is parallel to
The axial direction of the light transmitting-receiving window 103.In which, the shell 101 includes: the front cover 101a and rear cover mutually fastened
101b；Wherein, the front cover 101a and rear cover 101b forms a chamber 101c, the blood sugar test component 102 after fastening
It is mounted in the chamber 101c；The rear cover 101b is provided with the light transmitting-receiving window 103.The front cover 101a and it is described after
Covering 101b can be relatively fixed by nut and/or relatively fixed by buckle structure.
Optionally, the portable blood sugar measuring instrument further includes the power supply 109 being arranged in the shell 101, the electricity
Source 109 is used to provide operating voltage for the blood glucose measurement component 102.The power supply 109 can be lithium coin cells or can fill
Electrical storage cell.
With reference to Fig. 5-Fig. 7, Fig. 5 is a kind of structural schematic diagram of maintaining member provided in an embodiment of the present invention, and Fig. 6 is this hair
A kind of shell for taking formula glucometer and maintaining member that bright embodiment provides assemble schematic illustration, and Fig. 7 is that the present invention is real
A kind of top view for taking formula glucometer with maintaining member of example offer is provided.It is described to take formula blood glucose measurement in which
Instrument further include: the maintaining member 104 that the rear cover 101b deviates from the side the front cover 101a is set；Wherein, blood glucose is being carried out
When measurement, the maintaining member 104 is used for the shell 101 and user's skin surface is relatively fixed.Maintaining member 104 can be with
Including glue-line or cyclic annular wearing component.In mode shown in Fig. 5, maintaining member 104 has glue-line towards a side surface of skin,
To be fixed with skin attachement.
Wherein, as shown in figure 3, the surface the rear cover 101b has groove 107, the bottom setting of the groove 107 is
State light transmitting-receiving window 103；The maintaining member 104 has the convex portion 106 for being fixed in the groove 107, described
The position of the corresponding light transmitting-receiving window 103 of convex portion 106 has the through-hole for fixing glucose sensitive optical fibre 13.It maintains
Component 104 and rear cover 101b can be fixed to each other by matched screw thread, such as in the side wall and the lug boss of the groove 107
Divide 106 side that the screw thread being mutually matched is set, so that maintaining member 104 can removably be fixed on the rear cover
On 101b, as shown in fig. 6, the two can directly pass through rotary assembled or fractionation.
Optionally, light-guiding pillar 108 is installed, the light-guiding pillar 108 receives and dispatches window 103 with the light in the chamber 101c
Face setting, the part detection light signal transduction that the light-guiding pillar 108 is used to for the blood sugar test component 102 being emitted is extremely
The glucose-sensitive optical fiber 13, the fluorescence feedback signal that the glucose-sensitive optical fiber 13 is emitted are conducted to the blood
Sugar detection component 102.
In portable blood sugar measuring instrument described in the embodiment of the present invention, realization principle such as Fig. 8 of the blood sugar test component 12
It is shown.
With reference to Fig. 8, Fig. 8 is a kind of structural schematic diagram of blood glucose measurement component provided in an embodiment of the present invention, which surveys
Measuring component includes: light source device 11, and the light source device 11 is for emitting detection optical signal；Spectrum groupware 12, the light splitting group
Part 12 is used to for the detection optical signal being divided into two parts, and a part of detection optical signal passes 13 by glucose-sensitive optical fiber
It is directed at subcutaneous tissue liquid, to obtain fluorescence feedback signal；First photoelectric conversion processing circuit 14, the first photoelectric conversion processing
Circuit 14 is used to detect the fluorescence feedback signal by the glucose-sensitive optical fiber 13, generates the first electric signal；Second light
Electric conversion processing circuit 15, the second photoelectric conversion processing circuit 15 detect optical signal for detecting described in another part, raw
At the second electric signal.
Wherein, first electric signal and second electric signal are for calculating blood glucose value.First photoelectric conversion
Processing circuit 14 includes optical sensor, can detecte optical signal, and generate electric signal based on optical signal detecting result.Described second
Photoelectric conversion processing circuit 15 includes optical sensor, can detecte optical signal, and generate electric signal based on optical signal detecting result.
Optical sensor includes but is not limited to photoelectric tube.The first photoelectric conversion processing circuit 14 and second photoelectric conversion processing electricity
Road 15 all has integrated circuit and handles electric signal, such as analog to digital conversion circuit and amplifying circuit, photoelectric conversion circuit
Implementation be conventional design, technical solution of the present invention is not specifically limited its particular circuit configurations.
The spectrum groupware 12 includes: prism group, and the prism group includes the first prism 121 and the second rib of opposite fitting
Mirror 122；Semi-permeable membrane 123 positioned at first prism 121 and second prism 122 with respect to coating surface, the semi-permeable membrane
123 for being divided into two parts for the detection optical signal that the light source device 11 emits, so that a part of detection optical signal is logical
The incident subcutaneous tissue liquid of the glucose-sensitive optical fiber 13 is crossed, fluorescence feedback signal is formed, so that detection light described in another part
The incident second photoelectric conversion processing circuit 15 of signal, the second photoelectric conversion processing circuit 15 detect the incident inspection
Light signal forms second electric signal；The semi-permeable membrane 123 is part reflective semitransparent film.
Wherein, the fluorescence feedback signal conducts the incident prism group 12, portion by the glucose-sensitive optical fiber 13
Point fluorescence feedback signal reflexes to the first photoelectric conversion processing circuit 14 by the semi-permeable membrane 123, and described first
Photoelectric conversion processing circuit 14 detects the incident fluorescence feedback signal, forms first electric signal.
In mode shown in Fig. 8, first prism 121 and second prism 122 are sticked to form a regular hexagonal prism；Institute
Six sides for stating regular hexagonal prism are divided into three pairs facing each other；The middle vertical plane of first pair of opposite two sides is first rib
The interface of mirror 121 and second prism 122, the middle vertical plane are provided with the semi-permeable membrane 123；Second pair of opposite two sides
In, a side is that the first photoelectric conversion processing circuit 14 provides part the fluorescence signal, another side is described
Second photoelectric conversion processing circuit 15 provides and detects optical signal described in another part；Third is in opposite two sides, a side
Face receives the detection optical signal that the light source device 11 emits, another side is that the glucose-sensitive optical fiber 13 provides
A part of light detecting signal.
In the embodiment of the present invention, the light source device 11 can be LED (light emitting diode) or LD (semiconductor laser).
Optionally, the detection optical signal that the light source device 11 emits is yellow light.Show carrying out blood sugar test in actual application
When, when the glucose-sensitive optical fiber 13 carries out fluorescence feedback in subcutaneous tissue liquid, the measurement effect of yellow light is preferable.It needs
Bright, in the embodiment of the present invention, detection optical signal is not limited to yellow light, or the optical signal of its all band.
Described 13 one end of glucose-sensitive optical fiber is for relatively fixed with light transmitting-receiving window 103, to receive the blood
A part of light detecting signal that sugar detection component 102 exports, the other end have the probe for being placed in subcutaneous tissue；Its
In, the probe has the end of probe for being placed in subcutaneous tissue, and the length of the end of probe is 4mm-5mm.In the length
In range, it can effectively obtain the fluorescence feedback signal needed by subcutaneous tissue liquid, detected for blood glucose value.Specifically,
Described 13 one end of glucose-sensitive optical fiber receives a part of light detecting signal that the spectrum groupware 12 exports.
With reference to Fig. 9, Fig. 9 is the structural schematic diagram of another blood glucose measurement component provided in an embodiment of the present invention, shown in Fig. 9
Mode, on the basis of mode shown in Fig. 8, further includes: MCU (one chip microcomputer or single-chip microcontroller) 21, the MCU 21 with
The first photoelectric conversion processing circuit 14 and the second photoelectric conversion processing circuit 15 are all connected with, for according to described the
One electric signal and second electric signal calculate blood glucose value.
Optionally, the MCU 21 is also connect with the light source device 11, to control the work shape of the light source device 11
State.Specifically, the MCU 21 controls the light source device 11 and emits light detection light letter when receiving the first control instruction
Number, when receiving the second control instruction, the MCU 21 controls the light source device 11 and closes, and does not emit the light detection letter
Number.It can be disconnected by the conducting for the switch element being connect with the MCU 21 and input first control instruction or the
Two control instructions.As described in user's operation when switching elements conductive, first control instruction, user are inputted for the MCU 21
When operating switch element disconnection, second control is inputted for the MCU 21 and is referred to.The switch element can be opened for machinery
Pass or touch switch.
In other modes, first control instruction or the second control instruction can also be obtained automatically by sensor,
The sensor is based on the detection signal, judges that portable blood sugar measuring instrument is for obtaining detection signal, the MCU 21
It is no to be in use state, if it is, generating the first control instruction, and first control instruction is executed, controls the light source
Device 11 emits light detection optical signal, if it is not, then generating the second control instruction, and executes second control instruction, controls
The light source device 11 is closed, and does not emit the light detecting signal.The sensor is that setting is measured in the portable blood sugar
The pressure sensor of instrument and skin attachement surface shows use state if detection pressure value is greater than given threshold, it is on the contrary then
In non-working condition.
With reference to Figure 10, Figure 10 is the structural schematic diagram of another blood glucose measurement component provided in an embodiment of the present invention, described
Blood glucose measurement component further include: wireless communication module 31, the wireless communication module 31 are used to carry out data friendship with terminal device
Mutually.In mode shown in Figure 10, the blood glucose measurement component includes MCU 21, and the wireless communication module 31 and MCU 21 connects
Connect, in other modes, also can be set the wireless communication module 31 directly with the first photoelectric conversion processing circuit 14 and
The second photoelectric conversion processing circuit 15 can also be not provided with MCU 21 at this point it is possible to which MCU 21 is arranged.The terminal is set
Standby can be the electronic equipments such as mobile phone tablet computer laptop or desktop computer.
Wherein, the wireless communication module 31 can be Bluetooth wireless communication module, WIFI wireless communication module or he
Wireless communication module.In the embodiment of the present invention, for the wireless communication module 31 specific implementation without limitation.It is described
Wireless communication module 31 is used for at least one performed the following operations:
First way, the wireless communication module 31 are shown for the blood glucose value to be sent to the terminal device
Show.In which, needs to be arranged MCU 21 and connect for calculating the blood glucose value, the wireless communication module 31 and the MCU 21
It connects, the blood glucose value is sent to the terminal device.
The second way, the wireless communication module 31 is for receiving the control instruction that the terminal device issues.The party
MCU 21 can be set in formula, can also be not provided with MCU 21.The control instruction includes but is not limited to be used to control the light source
The instruction that device is opened or closed.
The third mode, the wireless communication module 31 are used to send first electric signal and second electric signal
To the terminal device, so that the terminal device is based on described in first electric signal and second electric signal calculating
Blood glucose value, and show the blood glucose value.MCU 21 can be set in which, can also be not provided with MCU 21.
When wireless communication module 31 and terminal device progress data interaction is arranged, in mode shown in Figure 10, the blood glucose is surveyed
Measuring component includes MCU 21, can also be not provided with MCU 21 Ru above-mentioned, at this time as shown in figure 11, Figure 11 mentions for the embodiment of the present invention
The structural schematic diagram of another the blood glucose measurement component supplied.
In the mode shown in Fig. 8-Figure 11, it is illustrated so that spectrum groupware 12 is regular hexagonal prism as an example.The embodiment of the present invention
In, the specific structure of spectrum groupware 12 is not specifically limited, as long as spectrum groupware 12 can be realized the beam splitting of detection optical signal,
Realize effective detection of intrinsic optical signal (the part detection optical signal of the second photoelectric conversion circuit 15 detection) and light signal fed back,
Belong to the protection scope of the embodiment of the present invention.For example, the spectrum groupware 12 can also be as shown in figure 12.
With reference to Figure 12, Figure 12 is the structural schematic diagram of another blood glucose measurement component provided in an embodiment of the present invention, Figure 12
In shown blood glucose measurement component, shown spectrum groupware 12 is square prism.The spectrum groupware 12 includes the first prism 121 and the
Two prisms 122, both for triangular prism, the two is sticked to form a square prism.In two opposite sides of the quadrangular, one
A side is that the first photoelectric conversion processing circuit 14 provides part the fluorescence signal, another side is second light
Electric conversion processing circuit 15 provides and detects optical signal described in another part；In other two opposite sides of the quadrangular, one
A side receives the detection optical signal that the light source device 11 emits, another side is the glucose-sensitive optical fiber 13
It is oppositely arranged and a part of light detecting signal is provided.
Figure 12 is only based on mode shown in Fig. 8, square as Figure 9-Figure 11 using the spectrum groupware 12 of different structure
In mode shown in Figure 12, MCU 21 or wireless communication module 31 is equally can be set in formula, and implementation can be retouched with reference to above-mentioned
It states, details are not described herein.
In the embodiment of the present invention, when the incident spectrum groupware 12 of the detection optical signal that light source device 11 is emitted, Ke Yizhi
The spectrum groupware is penetrated in access, or re-shoots light splitting group after adjusting detection light signal propagation path by the first light-guide device
Part.
In the embodiment of the present invention, spectrum groupware 12 and the glucose-sensitive optical fiber 13 can be directly oppositely arranged, will
A part of detection optical signal is directly transferred to the glucose-sensitive optical fiber 13, to obtain the fluorescence feedback signal, or
It is that there is the second light-guide device between the spectrum groupware 12 and the glucose-sensitive optical fiber 13, the spectrum groupware 12 is emitted
The detection optical signal by second light-guide device, after adjusting output detection light signal propagation path, described in re-incident
Glucose-sensitive optical fiber 13, the fluorescence feedback signal that the same glucose-sensitive optical fiber 13 exports are led by described second
Optical element after adjusting the fluorescence feedback signal propagation path, re-shoots the spectrum groupware 12.
In the embodiment of the present invention, spectrum groupware 12 can be with the optical sensor phase of the first photoelectric conversion processing circuit 14
To setting, the part fluorescence feedback signal that spectrum groupware 12 is emitted is directly transferred to the first photoelectric conversion processing circuit
14；Or spectrum groupware 12 can have a third light-guide device between the first photoelectric conversion processing circuit 14, and described point
The part fluorescence feedback signal that optical assembly 12 exports adjusts part fluorescence feedback signal propagation by the third light-guide device
Behind path, the first photoelectric conversion processing circuit 14 is re-shoot.
In the embodiment of the present invention, spectrum groupware 12 can be with the optical sensor phase of the second photoelectric conversion processing circuit 15
To setting, detection optical signal described in another part that spectrum groupware 12 is emitted is directly transferred to the second photoelectric conversion processing electricity
Road 15；Or spectrum groupware 12 can have the 4th light-guide device between the second photoelectric conversion processing circuit 15, and it is described
The part detection optical signal that spectrum groupware 12 exports adjusts part detection lightray propagation by the 4th light-guide device
Behind path, the second photoelectric conversion processing circuit 15 is re-shoot.
As above-mentioned, guide-lighting member can be set based on the layout installation requirements of each device in the blood glucose measurement component 102
Part, to adjust lightray propagation path, therefore each device is specifically laid out not office in shell 101 in the blood glucose measurement component 102
It is limited to mode shown in Fig. 1.
In a kind of mode, in the embodiment of the present invention, shown in the Computing Principle such as following formula (1) for blood glucose value:
BG=f (D, R) (1)
In above formula (1), BG (Blood glucose) indicates blood glucose value, and D indicates above-mentioned first electric signal, and R indicates above-mentioned the
Two electric signals, blood glucose value BG are the functions about the first electric signal D and the second electric signal R.
Can be based on blood glucose value known to standard device measurement multiple groups, and pass through the application blood sugar measuring system in every group of blood glucose
Corresponding first electric signal D and the second electric signal R under value can obtain corresponding first electricity of multiple groups difference blood glucose value in this way
Signal D and the second electric signal R.Function f (D, R) can be determined based on linear fit method.Based on determination function f (D, R), lead to
It crosses the blood sugar measuring system and obtains one group of first electric signal D and the second electric signal R, substituting into function f (D, R) can obtain pair
Answer blood glucose value.
If the blood glucose measurement component 102 is provided with MCU 21 to realize the automatic calculating of blood glucose value, two can be based on
Photoelectric conversion processing circuit detection data calculates blood glucose value, specifically can calculate institute's blood glucose value or base based on the table of comparisons
Blood glucose value is calculated in preset function relationship.First electric signal and second electric signal can also be sent to communication by the MCU
The terminal device of connection calculates blood glucose value by terminal device.
The portable blood sugar measuring instrument further includes the pcb board 105 being arranged in the shell 101.The blood sugar test
Each electronic component of component 102 is electrically connected with the pcb board 105.The light source device 11, first photoelectric conversion processing
Circuit 14 and the second photoelectric conversion processing circuit 15 are electrically connected with the pcb board 105.If being provided with the MCU
21, then the MCU 21 is electrically connected with the pcb board 105.If being provided with wireless communication module 31, wireless communication module 31
It is electrically connected with the pcb board 105, or is electrically connected by the MCU 21 with the pcb board 105.
The portable blood sugar measuring instrument can also include display device, which is arranged in the shell 101
Front display window, the display device is for showing the blood glucose value.If being provided with the MCU 21, can be set described
Display device is connect with the MCU 21.If the not set MCU 21 can be set the display device and pass through channel radio
Letter module 31 is connected with terminal device, to obtain the blood glucose value of terminal device calculating and show the blood glucose value.
It as can be seen from the above description, can be directly by Portugal in the portable blood sugar measuring instrument that technical solution of the present invention provides
One end of grape glucose sensitive optical fiber 13 is placed in subcutaneous tissue liquid, emits detection optical signal by light source device 11, so that a part of
The incident glucose-sensitive optical fiber 13 of the other end that the detection optical signal passes through the glucose-sensitive optical fiber 13, to obtain
Fluorescence feedback signal detects the fluorescence feedback signal by the first photoelectric conversion processing circuit 14, generates the first electric signal, leads to
It crosses and detects optical signal described in the second photoelectric conversion processing circuit 15 detection another part, generate the second electric signal, it finally can root
According to first electric signal and second electric signal, blood glucose value is calculated.As it can be seen that technical solution of the present invention is calibrated before factory
Afterwards or after user's self calibration, first electric signal can be directly based upon and second electric signal carries out blood glucose value inspection
It surveys, it is easy to operate, it is easy to use.
Each embodiment in this specification is described in a progressive manner, the highlights of each of the examples are with other
The difference of embodiment, the same or similar parts in each embodiment may refer to each other.
It should also be noted that, herein, relational terms such as first and second and the like are used merely to one
Entity or operation are distinguished with another entity or operation, without necessarily requiring or implying between these entities or operation
There are any actual relationship or orders.Moreover, the terms "include", "comprise" or its any other variant are intended to contain
Lid non-exclusive inclusion, so that article or equipment including a series of elements not only include those elements, but also
It including other elements that are not explicitly listed, or further include for this article or the intrinsic element of equipment.Do not having
In the case where more limitations, the element that is limited by sentence "including a ...", it is not excluded that in the article including above-mentioned element
Or there is also other identical elements in equipment.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention.
Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein
General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention
It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one
The widest scope of cause.
Claims (10)
1. a kind of portable blood sugar measuring instrument, which is characterized in that the portable blood sugar measuring instrument includes:
Blood sugar test component, the blood sugar test component lead to a part of detection optical signal for being emitted detection optical signal
It crosses glucose-sensitive fiber optic conduction and detects the fluorescence feedback signal to obtain fluorescence feedback signal to subcutaneous tissue liquid and obtain
First electric signal detects the second telecommunications of detection light signal acquisition described in another part；First electric signal and described second
Electric signal is for calculating blood glucose value；
Shell, the blood sugar test component are mounted in the shell；There is light to receive and dispatch window, the light on the surface of the shell
Transmitting-receiving window is used to provide part the detection optical signal for the glucose-sensitive optical fiber, is also used to quick by the glucose
The photosensitive fine acquisition fluorescence feedback signal.
2. portable blood sugar measuring instrument according to claim 1, which is characterized in that the shell includes: mutually to fasten
Front cover and rear cover；
Wherein, the front cover and the rear cover form a chamber after fastening, and the blood sugar test component is mounted in the chamber；
The rear cover is provided with the light transmitting-receiving window.
3. portable blood sugar measuring instrument according to claim 2, which is characterized in that further include: setting is carried on the back in the rear cover
Maintaining member from the front cover side；
Wherein, when carrying out blood glucose measurement, the maintaining member is used for the shell and user's skin surface is relatively fixed.
4. portable blood sugar measuring instrument according to claim 3, which is characterized in that cap surface has groove, institute after described
The bottom for stating groove is provided with the light transmitting-receiving window；
The maintaining member has for fixed convex portion in the groove, and the convex portion corresponds to the light transmitting-receiving
The position of window has the through-hole for fixing the glucose-sensitive optical fiber.
5. portable blood sugar measuring instrument according to claim 2, which is characterized in that light-guiding pillar is installed in the chamber,
The light-guiding pillar and light transmitting-receiving window face setting, the light-guiding pillar are used for the part for being emitted the blood sugar test component
The detection light signal transduction feeds back the fluorescence of the glucose-sensitive fiber exit to the glucose-sensitive optical fiber
Signal transduction is to the blood sugar test component.
6. portable blood sugar measuring instrument according to claim 1, which is characterized in that use glucose-sensitive optical fiber one end
In relatively fixed with light transmitting-receiving window, to receive a part of light detecting signal of blood sugar test component output,
The other end has the probe for being placed in subcutaneous tissue；
Wherein, the probe has the end of probe for being placed in subcutaneous tissue, and the length of the end of probe is 4mm-5mm.
7. portable blood sugar measuring instrument according to claim 1-6, which is characterized in that the blood sugar test component
Include:
Light source device, the light source device is for emitting the detection optical signal；
Spectrum groupware, the spectrum groupware are used to the detection optical signal being divided into two parts, a part of detection optical signal
By the glucose-sensitive fiber optic conduction to subcutaneous tissue liquid, to obtain fluorescence feedback signal；
First photoelectric conversion processing circuit, the first photoelectric conversion processing circuit are used to visit by the glucose-sensitive optical fiber
The fluorescence feedback signal is surveyed, the first electric signal is generated；
Second photoelectric conversion processing circuit, the second photoelectric conversion processing circuit is for detecting the letter of detection light described in another part
Number, generate the second electric signal.
8. portable blood sugar measuring instrument according to claim 7, which is characterized in that the spectrum groupware includes:
Prism group, the prism group include the first prism and the second prism of opposite fitting；
Positioned at the semi-permeable membrane of first prism and the opposite coating surface of second prism, the semi-permeable membrane is used for the light
The detection optical signal of source device transmitting is divided into two parts, so that a part of detection optical signal passes through the glucose-sensitive light
Fine incidence subcutaneous tissue liquid, forms fluorescence feedback signal, so that incident second photoelectricity of detection optical signal described in another part
Conversion processing circuit；
Wherein, for the fluorescence feedback signal by the incident prism group of the glucose-sensitive fiber optic conduction, part is described glimmering
Optical feedback signal reflexes to the first photoelectric conversion processing circuit by the semi-permeable membrane.
9. portable blood sugar measuring instrument according to claim 7, which is characterized in that the blood sugar test component further include:
MCU, the MCU are connect with the first photoelectric conversion processing circuit and the second photoelectric conversion processing circuit, are used
According to first electric signal and second electric signal calculating blood glucose value.
10. portable blood sugar measuring instrument according to claim 7, which is characterized in that further include: wireless communication module, institute
Wireless communication module is stated for carrying out data interaction with terminal device；
Wherein, the wireless communication module is used for at least one performed the following operations: the blood glucose value is sent to the end
End equipment shown, or receives control instruction that the terminal device issues or by first electric signal and described second
Electric signal is sent to the terminal device, so that the terminal device is based on first electric signal and second telecommunications
Number the blood glucose value is calculated, and shows the blood glucose value.
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|---|---|---|---|
| CN201910711609.2A CN110296970A (en) | 2019-08-02 | 2019-08-02 | Portable blood sugar measuring instrument |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910711609.2A CN110296970A (en) | 2019-08-02 | 2019-08-02 | Portable blood sugar measuring instrument |
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Family
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022012400A1 (en) * | 2019-08-19 | 2022-01-20 | Medtrum Technologies Inc. | Highly integrated analyte detection device |
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