CN110288669A - A kind of compression type ultra-wideband microwave tumor of breast imaging method - Google Patents
A kind of compression type ultra-wideband microwave tumor of breast imaging method Download PDFInfo
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- CN110288669A CN110288669A CN201910500198.2A CN201910500198A CN110288669A CN 110288669 A CN110288669 A CN 110288669A CN 201910500198 A CN201910500198 A CN 201910500198A CN 110288669 A CN110288669 A CN 110288669A
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- 238000007906 compression Methods 0.000 title claims abstract description 48
- 230000006835 compression Effects 0.000 title claims abstract description 45
- 208000026310 Breast neoplasm Diseases 0.000 title claims abstract description 19
- 238000003384 imaging method Methods 0.000 title claims abstract description 16
- 210000000481 breast Anatomy 0.000 claims abstract description 77
- 206010028980 Neoplasm Diseases 0.000 claims abstract description 20
- 238000005056 compaction Methods 0.000 claims abstract description 4
- 238000010226 confocal imaging Methods 0.000 claims abstract description 4
- 230000008520 organization Effects 0.000 claims abstract description 4
- 230000009471 action Effects 0.000 claims abstract description 3
- 238000000034 method Methods 0.000 claims description 10
- 230000008569 process Effects 0.000 claims description 5
- 238000003825 pressing Methods 0.000 claims description 4
- 230000002902 bimodal effect Effects 0.000 claims description 3
- 239000000284 extract Substances 0.000 claims description 3
- 230000001360 synchronised effect Effects 0.000 abstract 1
- 206010006187 Breast cancer Diseases 0.000 description 5
- 238000001514 detection method Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 208000019155 Radiation injury Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
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- 230000005672 electromagnetic field Effects 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 230000036210 malignancy Effects 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 238000009607 mammography Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000001931 thermography Methods 0.000 description 1
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- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T11/00—2D [Two Dimensional] image generation
- G06T11/003—Reconstruction from projections, e.g. tomography
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- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
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Abstract
The present invention relates to a kind of compression type ultra-wideband microwave tumor of breast imaging methods, including the following steps: building compression type MRI breast numerical model；The gray value of MRI image is mapped as different tissues in breast from the angle of image procossing, exports breast model, breast-air boundary is extracted with Canny algorithm, generates skin boundary；Select the breast of wherein side, tumor size and position are set, and assignment is carried out to the electromagnetic parameter value of various organization, after array antenna by being affixed on breast skin surface is compressed, interior tissue can be in compaction profile in the longitudinal direction, simultaneously can also be horizontally in extension distribution, breast integrally pushes, and the tumour for including in breast can be synchronized under the action of compression factor and be moved down；Aerial position is set, intramammary tumour is imaged using confocal imaging algorithm.
Description
Technical field
The invention belongs to technical field of biomedical detection, are related to a kind of compression type ultra-wideband microwave tumor of breast imaging side
Method.
Background technique
Tumor of breast is the highest malignancy disease of women disease incidence, the death rate occupy women's mortality of malignant tumors it
It is first.The diagnosis of early stage tumor of breast undoubtedly all has the survival rate at a specified future date of the treatment rate and patient that improve mastosis decisive
Meaning.The detection method of currently used early-stage breast cancer includes mammography, ultrasonograph technology, computer
Tomoscan, nmr imaging technique, thermal imaging detection etc., but all multi-methods have some disadvantages, and such as produce to human body
Raw radiation injury, image contrast be low, costly etc..The principle of ultra wide band Electromagnetic Wave Detection breast cancer is different biological groups
Absorption, reflection and the transmissison characteristic knitted to electromagnetic wave are different, when so that the pulse signal of antenna transmitting being propagated in breast tissue
Generated electromagnetic field is able to reflect the abundant information of malignant tissue.Ultra-wideband microwave signal has that radiant power is low, mesh simultaneously
The advantages such as the information amount of carrying is big, offer grade positioning is low with testing cost are marked, it can be as the conventional means of early stage breast cancer.
In the tumor of breast detection research of early stage, the model of use is usually relatively simple model, these models tool
There is symmetry, such as cuboid breast model, hemisphere breast model and cylindrical model.Cuboid breast model include skin layer,
Fat deposit (the inside includes some conduits and gland tissue etc.), tumour and rib cage layer.Hemisphere breast model and cylindrical breast mould
The setting of each breast tissue layer and rectangular body Model are essentially identical in type.
The case where detecting when these models seldom considered patient breast is by different oppressive forces when lying on the back.The present invention
The genuine compression type microwave breast model that becomes relatively is established based on the true MRI image of patient, keeps breast model truer, more meets
Detect environment.
Summary of the invention
The object of the present invention is to provide a kind of compression type ultra-wideband microwaves that early stage tumor of breast may be implemented and precisely detect
Tumor of breast imaging method.Technical scheme is as follows:
A kind of compression type ultra-wideband microwave tumor of breast imaging method, including the following steps:
(1) construct compression type MRI breast numerical model: when flat plate array antenna act on breast skin surface and push
Meanwhile flat plate array antenna is in contact with breast skin surface, and both pushing processes fit closely, a pressing face is formed,
It is inwardly compressed the breast in MRI figure is bimodal, longitudinally scaled compression, laterally appropriate broadening, is more than horizontal line in compression process
Part be all compressed to horizontal line position, each column presses compression factor longitudinal compression to corresponding position, constructs compression type MRI breast
Numerical model.
(2) different tissues in breast are mapped as from the angle of image procossing by the gray value of MRI image, export breast mould
Type extracts breast-air boundary with Canny algorithm, generates skin boundary；
(3) breast for selecting wherein side is arranged tumor size and position, and carries out to the electromagnetic parameter value of various organization
Assignment, after array antenna by being affixed on breast skin surface is compressed, interior tissue can be in compaction profile in the longitudinal direction, simultaneously
Can also be horizontally in extension distribution, breast integrally pushes, and the tumour for including in breast can synchronize under the action of compression factor
It moves down；
(4) aerial position is set, intramammary tumour is imaged using confocal imaging algorithm.
Detailed description of the invention
Fig. 1 breast compression schematic diagram
The compressed breast schematic diagram of Fig. 2
Fig. 3 skin boundary figure
The source Fig. 4 breast MRI figure
The discrete figure of Fig. 5 mild compression breast tissue
Fig. 6 severe compresses the discrete figure of breast tissue
Fig. 7 mild compression breast model knub position and aerial position figure
Fig. 8 severe compresses breast model knub position and aerial position figure
Fig. 9 mild compression breast model tumor imaging figure
Figure 10 severe compresses breast model tumor imaging figure
Specific embodiment
A kind of compression type ultra-wideband microwave tumor of breast imaging method, including the following steps:
(1) basic thought for constructing compression type MRI breast numerical model is when flat plate array antenna acts on skin of breast
Surface and while push, flat plate array antenna is in contact with breast skin surface, and both pushing processes fit closely, and is formed
One pressing face.Method based on pixel compression is inwardly compressed the breast in MRI figure is bimodal, longitudinally scaled compression, laterally
Appropriate broadening, to construct compression type breast model；
In compression process, the part more than horizontal line is all compressed to horizontal line position, and the compression factor of pressing of each column is longitudinally pressed
It is reduced to corresponding position, as shown in Figure 1；
(2) longitudinal direction is carried out to picture and presses column scan, compression processing is carried out by column to it, sets certain column starting point as A point, A
Point is, close to the skin surface of air, terminal is C point, and C point is breast most inner side, and pressure planes are B point, i.e., the point on horizontal line.
Compression processing in proportion, compression factor are carried out in that direction to all pixels point on this column of AC are as follows:
The location point D ' of point should meet after then any point D is compressed with it on AC:
DC=kDC (2)
Position after each point compresses successively is calculated, obtains compressed 2D breast schematic diagram, as shown in Figure 2；
(3) different tissues in breast are mapped as from the angle of image procossing by the gray value of MRI image, export breast mould
Type extracts breast-air boundary with Canny algorithm, generates skin boundary, as shown in Figure 3；
(4) breast for selecting wherein side is arranged tumor size and position, and carries out to the electromagnetic parameter value of various organization
Assignment.After array antenna by being affixed on breast skin surface is compressed, interior tissue can be in compaction profile in the longitudinal direction, simultaneously
It can also be horizontally in extension distribution.Breast integrally pushes, and such as comprising tumor information in breast, then tumour can be in compression factor
It synchronizes and moves down under effect；
(5) aerial position is set, intramammary tumour is precisely imaged using confocal imaging algorithm.It is being embodied
As can be seen that this compression type ultra-wideband microwave tumor of breast imaging method may be implemented early stage tumor of breast and precisely examine in mode
It surveys.
The present invention will be described with example with reference to the accompanying drawing.
(1) Fig. 4 is the source breast MRI figure, and picture is carried out one-off drawing processing first, is stretched as 600 × 600 pixels
Point makes the corresponding FDTD grid of each of picture pixel, which carries out in MATLAB, reads in first and only includes
The source figure of picture itself is translated into gray scale value matrix, and imresize order is recycled to stretch picture；
(2) compression type microwave breast 2D model, breast 2D model of the research by different oppressive forces are constructed.Picture is indulged
To column scan is pressed, compression processing is carried out by column to it, mild compression is constructed and severe compresses two kinds of compression type breast models, use
Canny algorithm identifies boundary, so that artificial addition skin layer is added according to boundary in the later period；
(3) gray value based on MRI figure respectively organizes breast to carry out discretization, the main method of discrete processes is setting
Pixel in a certain threshold range is classified as same class loading by gray value threshold value, and unified assignment is carried out to it, and table 1 is
Discrete specific threshold value table is organized,；
Table 1 organizes the threshold value of discrete processes to set table
(4) one layer of skin is added in discrete figure, on the basis of breast boundary profile, by around each boundary point 4 × 4
A pixel placement is skin, and skin thickness is about 4 grids, and skin gray value is assigned a value of by corresponding full-size(d) 2mm again
90, if Fig. 5 is the discrete figure of mild compression breast tissue, Fig. 6 is that severe compresses the discrete figure of breast tissue；
(5) usually only need to consider the breast on one side, interception right breast is added swollen as simulation model in breast
Tumor, setting tumour radius is 3mm, as shown in fig. 7, mild compression breast model knub position (60mm, 28mm), as shown in figure 8,
It is (60mm, 16mm) that severe, which compresses breast model knub position,；
(6) electromagnetic parameter assignment is carried out to each tissue, as shown in table 2；
The electrology characteristic representative value of common breast tissue when 2 6GHz of table
(7) aerial array is laid in skin surface, is replaced with point source, as shown in Figure 7,8, each antenna once emits letter
Number, other antennas receive signal, all reception signals are carried out imaging using confocal algorithm, as a result such as Fig. 9,10 institutes
Show；
It can be obtained by Fig. 9, mild compression breast model tumor imaging position is (60mm, 28mm), with default knub position phase
Together；It can be obtained by Figure 10, it is (60mm, 15.5mm) that severe, which compresses breast model tumor imaging position, with default knub position in the side Y
Upward gap 0.5mm, imaging position are essentially identical with predeterminated position.The above result shows that the compression type breast model is detecting
Early stage well adapting to property of mammary tumor may be implemented early stage tumor of breast and precisely detect.
Claims (1)
1. a kind of compression type ultra-wideband microwave tumor of breast imaging method, including the following steps:
(1) compression type MRI breast numerical model is constructed: when flat plate array antenna acts on breast skin surface and pushes same
When, flat plate array antenna is in contact with breast skin surface, and both pushing processes fit closely, and forms a pressing face, will
Breast in MRI figure is bimodal to be inwardly compressed, longitudinally scaled compression, laterally appropriate broadening, in compression process, more than horizontal line
Part is all compressed to horizontal line position, and each column presses compression factor longitudinal compression to corresponding position, constructs compression type MRI breast number
It is worth model.
(2) different tissues in breast are mapped as from the angle of image procossing by the gray value of MRI image, export breast model, used
Canny algorithm extracts breast-air boundary, generates skin boundary；
(3) breast for selecting wherein side, is arranged tumor size and position, and assign to the electromagnetic parameter value of various organization
It is worth, after the array antenna by being affixed on breast skin surface is compressed, interior tissue can be in compaction profile in the longitudinal direction, simultaneously also
Can be horizontally in extension distribution, breast integrally pushes, under the tumour for including in breast can synchronize under the action of compression factor
It moves；
(4) aerial position is set, intramammary tumour is imaged using confocal imaging algorithm.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112545475A (en) * | 2020-11-05 | 2021-03-26 | 中国船舶重工集团公司第七0九研究所 | Brain tumor detection method and device based on FDTD antenna array confocal imaging algorithm |
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|---|---|---|---|---|
| CN107212884A (en) * | 2017-05-11 | 2017-09-29 | 天津大学 | A kind of supine body position oppresses breast imaging method |
| CN108937929A (en) * | 2018-07-20 | 2018-12-07 | 王丰州 | A kind of design method of wearable microwave detection antenna and aerial array based on medical image |
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- 2019-06-11 CN CN201910500198.2A patent/CN110288669A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107212884A (en) * | 2017-05-11 | 2017-09-29 | 天津大学 | A kind of supine body position oppresses breast imaging method |
| CN108937929A (en) * | 2018-07-20 | 2018-12-07 | 王丰州 | A kind of design method of wearable microwave detection antenna and aerial array based on medical image |
Non-Patent Citations (1)
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| CN112545475A (en) * | 2020-11-05 | 2021-03-26 | 中国船舶重工集团公司第七0九研究所 | Brain tumor detection method and device based on FDTD antenna array confocal imaging algorithm |
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Application publication date: 20190927 |