CN110269598A - The blood pressure detecting method and apparatus of pressure and photoelectric sphyg wave are carried based on artery - Google Patents
The blood pressure detecting method and apparatus of pressure and photoelectric sphyg wave are carried based on artery Download PDFInfo
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- CN110269598A CN110269598A CN201810222461.1A CN201810222461A CN110269598A CN 110269598 A CN110269598 A CN 110269598A CN 201810222461 A CN201810222461 A CN 201810222461A CN 110269598 A CN110269598 A CN 110269598A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
- A61B5/0225—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers the pressure being controlled by electric signals, e.g. derived from Korotkoff sounds
- A61B5/02255—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers the pressure being controlled by electric signals, e.g. derived from Korotkoff sounds the pressure being controlled by plethysmographic signals, e.g. derived from optical sensors
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Abstract
The invention discloses a kind of blood pressure detecting method and apparatus that pressure and photoelectric sphyg wave are carried based on artery.The suitable pressure of load in human body artery table superficial part position, the diastolic pressure and systolic pressure for calculating the arterial pressure according to the photoelectric sphyg wave of the artery and its blood flow direction downstream, and then obtaining；Wherein select the shallow position pressurization of the skins tables such as arteria carotis, arteria brachialis, radial artery, femoral artery, posterior auricular artery, facial artery；Wherein photoelectric sphyg wave check bit is set to pressing position or in the downstream of the position blood flow direction, and selects at least one in the artery table superficial part position being connected to the artery, separately may be selected to increase photoelectric sphyg wave detection all the way in artery table superficial part position without pressurization.The detection device includes the road artery Zai Yaxin, at least photoelectric sphyg believes road and its structure all the way.Learning model acquisition blood pressure is established according to the road Zai Yaxin and the road photoelectric sphyg Bo Xin and believes the mapping relations between road, and mapping relations realize blood pressure detecting again accordingly.Present invention is mainly used for human bodies or animal blood pressure to detect.
Description
Technical field
The present invention relates to physiological detection fields, and in particular to but the including but not limited to detection functions such as blood pressure, heart rate are in one
The noninvasive physio-parameter detection of body.
Background technique
Existing blood pressure monitoring device is many kinds of, and there are Omron, nine peaces, Panasonic, CONTEC etc. in leading firm, but basic
It is all based on the cuff type monitoring of blood pressure method of oscillographic method.Although this method measured value is relatively accurate reliable, its disadvantage
It is clear that 1. continuous dynamic monitoring can not be carried out to blood pressure, the variation tendency of blood pressure can not be obtained；2. inflate cuff can to people with
Carry out nervous sense of discomfort, to influence monitoring of blood pressure result；3. the result obtained is relatively unilateral, only instantaneous " good " or
" bad ", uncertain factor.
Ambulatory blood pressure monitoring has the following advantages compared with Causal blood pressure:
(1) contingency for eliminating Causal blood pressure, the factors such as avoiding mood, movement, feed, smoke, drink influences blood pressure,
More reflect to objective reality blood pressure situation.
(2) ambulatory blood pressure would know that more blood pressure datas, can actually reflect changing rule of the blood pressure in whole day.
(3) it to early stage asymptomatic light hypertension or critical hypertension patient, improves recall rate and timely treatment can be obtained.
(4) ambulatory blood pressure can instruct drug therapy.It can be used to measure medication effect in many cases, help selects medicine
Object adjusts dosage and administration time.
A. it assists to provide the therapeutic scheme of individuation: instructing Treatment of Hypertension more meaningful compared with Causal blood pressure with ambulatory blood pressure monitoring,
Over the course for the treatment of, ambulatory blood pressure accurately reflects blood pressure, the valley top of antihypertensive drugs ratio and drug during medication
Therapeutic effect, avoid Causal blood pressure and bring deviation and cause treatment excessively or insufficient.By ambulatory blood pressure monitoring, comment
Estimate pretherapy and post-treatment blood pressure level, antihypertensive effect power and decompression duration etc., adjustable therapeutic scheme.Meanwhile it can be with
Drug formulation, time of administration and dosage are adjusted according to hypertensive patient's rule of life and fluctuation of blood pressure curve, to provide
More fine, individuation Treatment of Hypertension scheme.
B. it helps to restore normal arterial pressure circadian rhythm: needing to pay special attention to following clinical setting in hypertension therapeutic:
" 1. non-spoon type " hypertension: nighttime blood pressures descend below the 10% of daytime blood pressure.There is clinical research to show this kind of trouble
Person has higher target organ damage and cardiovascular disease risk, and prognosis is poor.Ambulatory blood pressure monitoring facilitates evaluation treatment to night
Between blood pressure influence, guidance selects reasonable therapeutic scheme.
2. blood pressure " morning peak ": it is now recognized that blood pressure " morning peak " and early morning coronary artery events and stroke are high-incidence related, although early morning
Platelet increases and fibrinolytic reduces the generation for having also assisted in above-mentioned event, and European Society of Hypertension emphasizes that doctor exists
While the aggregate level that reduces blood pressure, the control to blood pressure " morning peak " need to be paid special attention to.
3. nighttime blood pressures excessively reduction person: what nighttime blood pressures decrease beyond daytime blood pressure 20% also needs to arouse attention, night blood
Press through it is low may result in cerebral hypoperfusion, this kind of patient should be avoided in Treatment of Hypertension the caused nighttime blood pressures for the treatment of into
One step reduces.Ambulatory blood pressure reflects the concrete condition of patients' blood's fluctuation and circadian rhythm comprehensively, helps to adjust drug agent
Amount and administration time restore the normal blood pressure rhythm of body, avoid or damage of the alleviating hypertension to target organ, it has also become refer to
Lead the effective technology means of Treatment of Hypertension.
C. antihypertensive drugs is evaluated: by ambulatory blood pressure monitoring it will be seen that the valley top ratio of depressor, is conducive to reasonably select drop
Pressing object.Dose acts on blood pressure decreasing value and blood pressure reduction before terminal, subsequent dose use before valley top ratio refers to drug
The ratio of peak value, is expressed as a percentage.Pass through the assessment of valley top ratio, it will be appreciated that antihypertensive drugs is to the steady of controlling of blood pressure
Degree, a kind of antihypertensive drugs should at least keep 50%~60% peak effect in paddy effect.But it evaluates in actual operation
The drug antihypertensive effect that should be noted that when the valley top ratio of drug is faint, and the pressure value of paddy effect and peak effect is not much different,
Valley top ratio is close to 100% at this time, but does not have therapeutic potential.And some drug antihypertensive effects is stronger, valley top ratio is high, answers
Notice that its lasting stronger antihypertensive effect is likely to result in night and asks that blood pressure decline is too low, it is dangerous to increase cerebral arterial thrombosis.
D. assist evaluation efficacy of antihypertensive treatment: ambulatory blood pressure can blood pressure to patient and circadian rhythm make assessment, relatively even survey
Blood pressure reflects the blood pressure situation of patient more comprehensively, objectively, has its special value in terms of evaluating efficacy of antihypertensive treatment.
E. judging hypertensive patient, whether there is or not target organ (organ vulnerable to hypertension damage) damages: having myocardial hypertrophy, eyeground dynamic
The hypertensive patient of vascular lesion or change in renal function, day and night between difference it is smaller.
Value of the ambulatory blood pressure monitoring in terms of prediction target organ damage and cardiovascular disease risk is greater than consulting room Causal blood pressure.Just
Normal Diurnal blood pressure change rule is substantially in bimodal and a low long handle spoon type, and this Diurnal blood pressure change is to body activities, protection
Heart and brain pipe normal configuration plays an important role with function.
Nighttime blood pressures are persistently increased makes cardiovascular system be in high-level blood pressure load state for a long time with circadian rhythm disappearance, this
Class patient's target organ damage aggravates, poor prognosis, and the disease incidence and case fatality rate of the complication such as the heart, brain, kidney are higher.
F. the time that interior cardiovascular and cerebrovascular disease breaks out is pressed from both sides in prediction one.Morning blood pressure jumps, and cardiovascular and cerebrovascular disease most easily occurs.
G. ambulatory blood pressure is significant to judging prognosis.Compared with conventional blood pressure, 24 hours its case fatality rate of high blood pressure person and
Incidence of cardiovascular disease is above 24 hours relatively low persons of blood pressure.Especially the right side of fifty, diastolic pressure < 16.0kPa
(105mmHg), and previous absent cardiovascular onste person, measurement ambulatory blood pressure are more meaningful, can direction of medication usage, prediction is cardiovascular
Onste；
Summary of the invention
In order to overcome the shortcomings of oscillographic method and Ke Shi because method blood pressure not can be carried out dynamic monitoring, it is an object of the invention to mention
It is accurately examined for the blood pressure based on a kind of correlation for carrying pressure signal and Photoelectric Pulse Wave Signal or its wave portion based on artery
Survey or continuous dynamic monitoring method and its device.
It is a kind of based on artery carry pressure and photoelectric sphyg wave blood pressure detecting method and device thereof, including the road artery Zai Yaxin and
Luminous point pulse believes road, and time upper interrupted blood pressure detecting, which not only may be implemented, can also realize the continuous blood pressure of dynamic and heart rate inspection
It surveys；
The method test object includes the blood pressure and heart rate of humans and animals；
The described optics pulse letter road Detection wavelength includes but including but not limited to 400~1550nm.
The road the artery Zai Yaxin detection range includes but including but not limited to 10~250mmHg.
The blood pressure detecting method, by but include but is not limited to wear structure adjust, air pump or manually by or put
The pressure that adds deduct mode realizes study or the calibration process of blood pressure model, 0~300mmHg of pressure regulation spectrum.
The detection position is that the typical shallow position of artery table includes but is not limited to that arteria carotis, arteria brachialis, radial artery, stock are dynamic
The corresponding shallow position of skin table such as arteries and veins, posterior auricular artery, facial artery, superficial temporal artery, anterior tibial artery and arteria dorsalis pedis.
A kind of detection method for the blood pressure being carried pressure and photoelectric sphyg wave based on artery, is depressed, pulse photoelectricity using artery
Wave weakens this feature, establishes characteristic signal mapping relations between photoelectric sphyg wave and artery pressure；Characteristic signal passes through
Including but not limited to frequency spectrum algorithm, median filtering algorithm or sliding average algorithm etc. eliminate it from detection signal, are believed
It makes an uproar than higher signal.Characteristic signal includes but is not limited to the variation of moulding pressure mean value, moulding pressure extreme value, moulding pressure
Value, photoelectric sphyg wave mean value, photoelectric sphyg wave extreme value or photoelectric sphyg wave changing value etc..According to pressure related signal feature and with
The signal characteristic of its photoelectric sphyg wave synchronized establishes mapping model, and mapping model includes but is not limited to linear analogue or multinomial
Simulation.
According to mapping model, feature and photoelectric sphyg wave characteristic are pressed in conjunction with synchronous carry measured in real time, returns to calculate and realize
Dynamically noninvasive, Time Continuous or interrupted blood pressure detecting, and quickly, expense it is low, easy to operate, be mainly used for human or animal's blood pressure or
Blood pressure and heart rate detection have market prospects.
Detailed description of the invention
Fig. 1 is the device of the invention system schematic；
Fig. 2 is the method for the present invention pressure obtained and photoelectric sphyg fluctuating range mapping model figure；
Fig. 3 is the curve example of the present invention real-time continuous monitoring of blood pressure detected；
Specific embodiment
Below in conjunction with attached drawing, the present invention is described further.
Fig. 1 shows working model figure.The road artery Zai Yaxin 1 is acted on pressure in a manner of 2 progress pressure or decompression
The shallow position of brachial artery table, and tension detection is carried out in same position, photoelectric sphyg is carried out through the shallow position of artery table in 3 indicating ranges
The detection of wave.To realize ambulatory blood pressure monitoring, then through monitoring the artery Photoelectric Pulse Wave Signal under non-pressurized condition at 7.Together
Step obtains signal, after signal processing, then through including but is not limited to following mapping pressure and photoelectric sphyg wave or pressure and
Photoelectric sphyg wave wave portion, establish as Fig. 2 learning model (with pressure signal through intermediate value or equalization processing after and photoelectricity arteries and veins
Wave fluctuating range of fighting is characterized mapping, and pressurizing device 2 is that common cuff air bag is worn on the shallow position of upper arm arteria brachialis table, passes through tune
The elastic progress pressure adjusting of cuff is saved, photoelectric sphyg signal refers to folder detection middle finger finger pulp using transmission-type)；
Dotted line frame section 4 is that photoelectric sphyg wave fluctuating range starts the critical section reduced, and dotted line frame section 6 is photoelectric sphyg wave
End critical section.Pressure spot is found from critical section, according to traditional oscillographic method or Ke Shi because method all has a method error, however
Under the mapping of this method, using the process data in the intermediate section 5 in two critical sections, simulated using least square method scheduling algorithm,
The mathematical relationship of including but not limited to Linear Mapping is obtained, this example is with linear analogue mapping relations: y=kx+b, x representative pressure letter
The pressure value of road sensing, y represent the signal fluctuation width on the road photoelectric sphyg Bo Xin at the position indicated by 3 in Fig. 1 synchronous with x
Value, the example map slope k=- 0.1148, intercept b=15.3, i.e., the mapping between pressure and photoelectric sphyg wave fluctuation amplitude is closed
System: y=-0.1148x+15.3；The photoelectric sphyg wave fluctuation dead line intersection point abscissa of photoelectric sphyg cut-off region is on the right side of 6th area
Correspond to systolic pressure at that time.The photoelectric sphyg wave ends line options but is not limited to its noise mean value, its noise mean value and noise
The sum of 2 times of standard deviation or 3 times values, 2 times of noise standard deviation or 3 times of values or zero；In example, noise standard deviation is taken
0.164 2 times of values are dead line, y=0.328, with two line intersection point abscissa x=130.4mmHg, the as contraction of the period
Pressure；It is x with artificial line intersection point abscissa similarly by the photoelectric sphyg amplitude mean value line y=8.126 on the left of critical 4th area of section
=62.5mmHg, as diastolic pressure.Calculating that is such then completing mapping relations, accurate systolic pressure and diastolic pressure.
By the model in Fig. 2, if 2 pressure is less than systolic pressure in Fig. 1, especially less than systolic pressure and diastolic pressure is flat
When mean value, continuous synchronization detection includes but is not limited to the photoelectricity arteries and veins of 2 pressure in Fig. 1, the photoelectric sphyg wave at position 3 and position 7
It fights wave, according to the feature of its two-way Photoelectric Pulse Wave Signal, including but not limited to synchronous photoelectric sphyg wave fluctuating range, photoelectricity
Pulse wave fluctuating range mean value, photoelectric sphyg wave fluctuating range standard deviation and pressure value of synchronization etc., in conjunction with what is learnt
Relationship model returns and calculates continuous systolic pressure and diastolic pressure.In embodiment, cuff adjusts pressure sensing mean value about 70mmHg,
If the downstream photoelectricity amplitude of synchronzed press artery connection is A (t), Dynamic contraction pressure is calculated as BP (t)=A (t)/0.1148
+70；Simultaneously according to the artery photoelectric sphyg wave fluctuating range B (t) under synchronous non-pressure effect, synchronous diastolic pressure DBP (t) is calculated
Circadian blood pressure profile is so then realized in-B (t)/0.1148=BP (t), and it is as shown in Figure 3 that example continuously measures curve.Benefit it
One is by adjusting elastic, the adjusting of Lai Shixian pressing force worn, so that tested person can know ambulatory blood pressure information,
Also it is unlikely to the sense of discomfort for having over-voltage, continuous dynamic monitoring can be realized without air pump or air valve etc..
Claims (10)
1. a kind of detection method and device of the human blood-pressure for carrying pressure and photoelectric sphyg wave based on artery, it is characterised in that: be based on
Photoelectric sphyg wave and artery carry pressure relevance modeling, obtain systolic pressure and diastolic pressure by model, be achieved in time discrete or
The blood pressure detecting of Time Continuous；The device of the method include at least all the way the road photoelectric sphyg Bo Xin, at least all the way artery carry pressure
Believe road and fixed structure.
2. the apparatus according to claim 1, it is characterised in that: the wavelength that the road the photoelectric sphyg Bo Xin is included exists
400nm~2000nm, optical sensor sensitizing range corresponding light source wavelength, typical wavelength band: 400nm~1550nm.
3. the apparatus according to claim 1, it is characterised in that: the road artery Zai Yaxin has pressurization function, pressurization
Mode includes but is not limited to pump the pressurization of manual or other power forms, especially by adjustment structure, realizes pressure range
For 0~300mmHg, pressure transducer precision is better than 5mmHg.
4. the apparatus according to claim 1 structure, it is characterised in that: capable of installing the road artery Zai Yaxin, to be fixed on it tested
On position；The road photoelectric sphyg Bo Xin can be installed and make its be fixed on from containing artery carry pressure check bit be set to starting point to its blood flow side
To downstream on the tested artery table superficial part position being connected, and Photoelectric Detection mode includes but is not limited to skin reflex formula or thoroughly
Penetrate formula.May be selected it is non-load press the shallow position of arteries and veins table increase it is non-load pressure condition under photoelectric sphyg wave.
5. device according to claim 4, it is characterised in that: the material that the apparatus structure plays support is low drawing
The material of stretching strain；There is pressure regulating mechanism in described device structure, when carrying out model learning or discrete blood pressure detecting, need
It wants accordingly to be adjusted when boost or depressurization；When carrying out Circadian blood pressure profile, the adjustment structure is adjusted, makes its typical pressure
Not higher than the mean value of systolic pressure at that time and diastolic pressure, not more than systolic pressure, while pressure believes road and the road photoelectric sphyg Bo Xin
It is fluctuated with synchronous, at this time adjustment structure solid lock.
6. device according to claim 4, it is characterised in that: it is that typical artery table is shallow that the artery, which carries and presses tested position,
Position includes but is not limited to arteria carotis, arteria brachialis, radial artery, femoral artery, posterior auricular artery, facial artery, superficial temporal artery, anterior tibial artery
The corresponding shallow position of skin table with arteria dorsalis pedis etc..
7. according to the method described in claim 1, it is characterized by: the method be using act on eparterial pressure from
Zero is gradually increased until, when the blood flow for passing through the artery, corresponding this is lighted downstream during by the complete choked flow of arterial blood
The fluctuation signal of the artery photoelectric sphyg wave in direction starts to reduce, this pressure is equal to arterial pressure minimum；Arterial blood at this
Stream is disappeared since the fluctuation signal of the artery photoelectric sphyg wave in the direction downstream that should be lighted by complete choked flow, this pressure
Equal to arterial pressure maximum.If pressurized portion is position described in claim 6, the arterial pressure minimum and maximum point
Human body diastolic pressure and systolic pressure are not corresponded to.Pressing speed requires < 10mmHg/ seconds, and includes but is not limited at the uniform velocity to pressurize.
8. according to the method described in claim 1, it is characterized by: can also lead to other than the pressuring method in claim 7
Cross decompression process and obtain human body systolic pressure and diastolic pressure: in decompression process, the critical pressure occurred when photoelectric sphyg fluctuation is corresponding
For systolic pressure；Continue to pressurize, until photoelectric sphyg fluctuation no longer significantly increases critical pressure when obviously weakening with tension fluctuation
As diastolic pressure.Decompression rate requires < 10mmHg/ seconds, and includes but is not limited at the uniform velocity to depressurize.
9. according to claim 7 or process according to any one of claims 8, it is characterised in that: the artery of synchronization gain carry pressure signal with
Photoelectric Pulse Wave Signal or their wave portion have a very high correlation, the method for signal processing include but including but not
It is limited to the reductions such as Fourier algorithm, median filtering, moving average filtering, least square method, derivative processing, it is special obtains high s/n ratio
Reference number carries pressure signal using photoelectric sphyg signal and artery and establishes feature correlation map, and mapping relations include but is not limited to
Linear formula or polynomial mathematical model are simulated, according to the mathematical model under artery different pressures state, calculates separately critical pressure
Force value can get accurately systolic pressure and diastolic pressure.
10. the blood pressure detecting of Time Continuous according to claim 1 is based on signal processing as claimed in claim 9 and mould
Type, it is characterised in that: the artery table superficial part position can load smaller pressure, and mode is not limited to cuff air bag, after wearing, with
Draw or button mode adjusting elasticity and air pump and valve and nonessential, pressure are less than the tested daily systolic pressure of individual, typical pressure value
Less than the average value of daily systolic pressure and diastolic pressure；It is connected to before continuous monitoring synchronzed press position and after pressurized portion with the artery
Artery photoelectric sphyg wave and the pressure that is loaded of artery, believed according to two-way photoelectric sphyg Bo Xin road feature and synchronous pressure
Road feature passes through the mathematical model recurrence measured and calculates the Circadian blood pressure profile, it can be achieved that continuous in time.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810222461.1A CN110269598A (en) | 2018-03-15 | 2018-03-15 | The blood pressure detecting method and apparatus of pressure and photoelectric sphyg wave are carried based on artery |
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| CN201810222461.1A CN110269598A (en) | 2018-03-15 | 2018-03-15 | The blood pressure detecting method and apparatus of pressure and photoelectric sphyg wave are carried based on artery |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111839487A (en) * | 2020-06-18 | 2020-10-30 | 郑昕 | Blood pressure measuring method and system |
| CN112641433A (en) * | 2020-12-21 | 2021-04-13 | 上海连尚网络科技有限公司 | Method and equipment for measuring pulse information by pulse feeling equipment |
| CN113397478A (en) * | 2020-11-09 | 2021-09-17 | 华东理工大学 | Automatic pressurization control method for pulse diagnosis device |
-
2018
- 2018-03-15 CN CN201810222461.1A patent/CN110269598A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111839487A (en) * | 2020-06-18 | 2020-10-30 | 郑昕 | Blood pressure measuring method and system |
| CN111839487B (en) * | 2020-06-18 | 2022-12-23 | 郑昕 | Blood pressure measuring system without air bag |
| CN113397478A (en) * | 2020-11-09 | 2021-09-17 | 华东理工大学 | Automatic pressurization control method for pulse diagnosis device |
| CN112641433A (en) * | 2020-12-21 | 2021-04-13 | 上海连尚网络科技有限公司 | Method and equipment for measuring pulse information by pulse feeling equipment |
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Application publication date: 20190924 |