CN110265140A - Foot deformity detection model, foot deformity detection system and foot deformity detection method - Google Patents

Foot deformity detection model, foot deformity detection system and foot deformity detection method Download PDF

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Publication number
CN110265140A
CN110265140A CN201910127177.0A CN201910127177A CN110265140A CN 110265140 A CN110265140 A CN 110265140A CN 201910127177 A CN201910127177 A CN 201910127177A CN 110265140 A CN110265140 A CN 110265140A
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foot
image information
image
foot deformity
deformity
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黄宗祺
陈俊文
谢柏欣
廖英凯
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China Medical University Hospital
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China Medical University Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50Clinical applications
    • A61B6/505Clinical applications involving diagnosis of bone
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00Pattern recognition
    • G06F18/20Analysing
    • G06F18/24Classification techniques
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/04Architecture, e.g. interconnection topology
    • G06N3/045Combinations of networks
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients

Abstract

The present invention provides a kind of foot deformity detection system, includes an image acquisition unit and a non-transient machine-readable medium.Target the inner side of the foot position X-ray image information of the image acquisition unit to obtain a subject.Non-transient machine-readable medium includes a storage element and a processing unit.Storage element is to store foot deformity detection program.When foot deformity detects the foot deformity type and foot deformity occurrence degree when program is executed by processing unit to judge subject.Whereby, foot deformity detection system of the invention can effectively promote accuracy and the susceptibility of foot deformity detection, and can provide instant and effective foot deformity check and evaluation result.

Description

Foot deformity detection model, foot deformity detection system and foot deformity detection method
Technical field
The invention relates to a kind of medical information analysis model, system and method, especially a kind of foot deformity detection Model, foot deformity detection system and foot deformity detection method.
Background technique
Until today, the quickest and the most direct method whether foot deformity occurs that detects is by image analysing computer Mode assesses the dissection geometrical construction of foot, wherein being again that detection foot deformity is most widely used with X-ray image analysis Image analysing computer detection method.It still needs to whether however, being occurred with X-ray image analysis mode detection foot deformity through analyst couple Skeletal image is analyzed, and is to be easy in subsequent interpretation X optical image because the different of different analysts compare habit and produce Raw different diagnostic result causes the existing known accuracy by the progress foot deformity judgement of X-ray image analysis mode more not It is good.
Due to the development of Medical Imaging Technology, Magnetic resonance imaging (Magnetic Resonance Imaging, MRI) is opened Begin to be applied in detection relevant to foot deformity, since Magnetic resonance imaging can effectively obtain complete foot three-dimensional structure shadow Picture makes it have efficient detection precision.Not only need consuming higher however, carrying out foot deformity detection with Magnetic resonance imaging Cost, the time of detection is also longer, be with using Magnetic resonance imaging carry out foot deformity diagnosis in current practice application side Face is less universal.
Therefore, a kind of foot deformity detection system with pin-point accuracy rate and quickly detected how is developed, actually a tool Commercially valuable technical task.
Summary of the invention
The purpose of the invention is to provide the detections of a kind of foot deformity detection model, foot deformity detection system and foot deformity Method can provide instant (real by the determination module automated under the basis of a large amount of X-ray image information Time) and accurate foot deformity check and evaluation is as a result, using the foundation as the monitoring of the subsequent state of an illness or curative effect evaluation.
An aspect of the invention is to be to provide a kind of foot deformity detection model, and it includes following set-up steps.Obtain one Referring to information bank, wherein above-mentioned include multiple reference the inner side of the foot position X-ray image information referring to information bank.Before carrying out an image Processing step is that each image size referring to the inner side of the foot position X-ray image information is adjusted using an image information editor module And an image black white contrast, to obtain multiple standardization the inner side of the foot positions X-ray image information.A Feature Selection step is carried out, It is special to obtain at least one image after analyzing standardization the inner side of the foot position above-mentioned X-ray image information using a characteristic selecting module Value indicative.A training step is carried out, is that at least one image feature value above-mentioned is passed through into a convolution neural network learning point Class device is trained and reaches convergence, to obtain foot deformity detection model above-mentioned, wherein foot deformity detection model above-mentioned is to use To judge the foot deformity type and a foot deformity occurrence degree of a subject.
According to foot deformity detection model above-mentioned, wherein convolutional neural networks Study strategies and methods above-mentioned can be Inception-ResNet-v2 convolutional neural networks.
According to foot deformity detection model above-mentioned, wherein image pre-treatment step above-mentioned can be more to each referring to the inner side of the foot Position X-ray image information carries out image chroma extension processing.
According to foot deformity detection model above-mentioned, wherein the image format above-mentioned referring to the inner side of the foot position X-ray image information Can for digital medical image storage standard agreement (Digital Imaging and Communications in Medicine, DICOM image format).
According to foot deformity detection model above-mentioned, wherein foot deformity type above-mentioned can be flexibility flat foot or structure Property flat foot.
According to foot deformity detection model above-mentioned, wherein foot deformity occurrence degree above-mentioned can be apodia, slight foot Deformity, moderate foot deformity or severe foot deformity.
According to foot deformity detection model above-mentioned, wherein may include respectively in a left foot referring to the inner side of the foot position X-ray image information Side position X-ray image information and a right the inner side of the foot position X-ray image information.
Another aspect of the invention is to be to provide a kind of foot deformity detection system, and the foot to judge subject is abnormal Shape type and a foot deformity occurrence degree, and foot deformity detection system includes an image acquisition unit and a non-transient machine Device readable media.Target the inner side of the foot position X-ray image information of the image acquisition unit to obtain subject.Non-transient machine Readable media signal connects image acquisition unit above-mentioned, and non-transient machine-readable medium includes at a storage element and one Unit is managed, wherein storage element detects program to store target the inner side of the foot position X-ray image information above-mentioned and a foot deformity, And processing unit is to execute foot deformity detection program above-mentioned.Wherein, foot deformity detection program above-mentioned includes that a foot is abnormal Shape detection model establishes subprogram and foot deformity detection subprogram.Foot deformity detection model establishes subroutine pack containing a reference Information bank obtains module, one referring to image information editor module, a characteristic selecting module and a training module.Referring to information bank Obtaining module is to obtain one referring to information bank, wherein above-mentioned include multiple reference the inner side of the foot position X-ray shadow referring to information bank As information.It is each image size and a shadow referring to the inner side of the foot position X-ray image information of adjustment referring to image information editor module As black white contrast, to obtain multiple standardization the inner side of the foot positions X-ray image information.Characteristic selecting module is aforementioned to analyze Standardization the inner side of the foot position X-ray image information after at least one referring to image feature value.Training module is to will be aforementioned At least one be trained referring to image feature value by a convolution neural network learning classifier and reach convergence, with One foot deformity detection model.Foot deformity detects subroutine pack and chooses mould containing a target image information editing module, a target signature Block and a comparison module.Target image information editing's module is a shadow of adjustment target the inner side of the foot position X-ray image information above-mentioned As size and an image black white contrast, to obtain a standardization target the inner side of the foot position X-ray image information.Target signature is chosen Module be to analyze after the X-ray image information of standardization target the inner side of the foot above-mentioned position at least one target image feature Value.Comparison module is to be divided at least one target image characteristic value above-mentioned with foot deformity detection model above-mentioned Analysis to obtain a target image characteristic value weighted data, and analyzes target image characteristic value weighted data above-mentioned, tested to obtain The foot deformity type and foot deformity occurrence degree of person.
According to foot deformity detection system above-mentioned, wherein convolutional neural networks Study strategies and methods above-mentioned can be Inception-ResNet-v2 convolutional neural networks.
According to foot deformity detection system above-mentioned, wherein above-mentioned can be more to each reference referring to image information editor module The inner side of the foot position X-ray image information carries out image chroma extension processing, and target image information editing module above-mentioned can be more to mesh It marks the inner side of the foot position X-ray image information and carries out image chroma extension processing.
According to foot deformity detection system above-mentioned, wherein the image format of target the inner side of the foot above-mentioned position X-ray image information It can be the image format of digital medical image storage standard agreement, the image lattice above-mentioned referring to the inner side of the foot position X-ray image information Formula can be the image format of digital medical image storage standard agreement.
According to foot deformity detection system above-mentioned, wherein foot deformity type above-mentioned can be flexibility flat foot or structure Property flat foot.
According to foot deformity detection system above-mentioned, wherein foot deformity occurrence degree above-mentioned can be apodia, slight foot Deformity, moderate foot deformity or severe foot deformity.
According to foot deformity detection system above-mentioned, wherein may include respectively in a left foot referring to the inner side of the foot position X-ray image information Side position X-ray image information and a right the inner side of the foot position X-ray image information, target the inner side of the foot position above-mentioned X-ray image information may include Position X-ray image information and a right the inner side of the foot position X-ray image information on the inside of one left foot.
Another aspect of the invention is to be to provide a kind of foot deformity detection method, and it includes following step.There is provided just like Foot deformity detection model described in leading portion.The target the inner side of the foot position X-ray image information of one subject is provided.To mesh above-mentioned It marks the inner side of the foot position X-ray image information and carries out pre-treatment, be to adjust target the inner side of the foot using image information editor module above-mentioned An image size and an image black white contrast for position X-ray image information, to obtain a standardization target the inner side of the foot position X-ray shadow As information.Using after the X-ray image information of characteristic selecting module analytical standard target the inner side of the foot above-mentioned position at least one Image feature value.At least one image feature value above-mentioned is analyzed using foot deformity detection model above-mentioned, it is tested to judge The foot deformity type and a foot deformity occurrence degree of person.
According to foot deformity detection method above-mentioned, wherein image information editor module above-mentioned can be more to target the inner side of the foot Position X-ray image information carries out image chroma extension processing.
According to foot deformity detection method above-mentioned, wherein the image format of target the inner side of the foot above-mentioned position X-ray image information It can be the image format of digital medical image storage standard agreement.
According to foot deformity detection method above-mentioned, wherein target the inner side of the foot above-mentioned position X-ray image information may include a left side The inner side of the foot position X-ray image information and a right the inner side of the foot position X-ray image information.
Whereby, foot deformity detection model of the invention, foot deformity detection system and foot deformity detection method are by will be in foot Side position X-ray image information and target the inner side of the foot position X-ray image information carry out image and standardize pre-treatment, and utilize Feature Selection Module analysis and after at least one image feature value, then with convolutional neural networks Study strategies and methods image feature value is carried out Training, whether quickly and accurately to judge that the foot deformity of subject occurs, foot deformity type and foot deformity occurrence degree, And the detection reproducibility with height.Furthermore by the inclusion of the foot deformity detection model energy of convolutional neural networks Study strategies and methods Accuracy and the susceptibility for effectively promoting foot deformity detection, make foot deformity detection model of the invention, foot deformity detection system And foot deformity detection method has excellent clinical application potentiality.
Detailed description of the invention
Fig. 1 is the establishment step flow chart for being painted the foot deformity detection model of an embodiment of the present invention.
Fig. 2A is the configuration diagram for being painted the foot deformity detection system of another embodiment of the present invention.
Fig. 2 B is the configuration diagram of the foot deformity detection program for the foot deformity detection system for being painted Fig. 2A.
Fig. 3 is the step flow chart for being painted the foot deformity detection method of another embodiment of the present invention.
Fig. 4 is the configuration diagram for being painted the convolutional neural networks Study strategies and methods of foot deformity detection model of the invention.
[main element symbol description]
100: foot deformity detection model
110: obtaining one referring to information bank
120: carrying out an image pre-treatment step
130: carrying out a Feature Selection step
140: carrying out a training step
200: foot deformity detection system
300: image acquisition unit
400: non-transient machine-readable medium
411: target the inner side of the foot position X-ray image information
410: storage element
420: processing unit
430: foot deformity detects program
440: foot deformity detection model establishes subprogram
441: obtaining module referring to information bank
442: referring to image information editor module
443: characteristic selecting module
444: training module
450: foot deformity detects subprogram
451: target image information editing's module
452: target signature chooses module
453: comparison module
500: foot deformity detection method
510: foot deformity detection model is provided
520: the target the inner side of the foot position X-ray image information of subject is provided
530: pre-treatment is carried out to target the inner side of the foot position X-ray image information
540: using characteristic selecting module analytical standard target the inner side of the foot position X-ray image information after at least one Image feature value
550: analyzing at least one image feature value using foot deformity detection model
600: convolutional neural networks Study strategies and methods
601: target image characteristic value weighted data
Specific embodiment
It is following that each embodiment of the present invention will be discussed in greater detail.However, this embodiment can answering for various concept of the invention With can specifically be carried out in a variety of different particular ranges.Specific embodiment be only for the purpose of description, and not by It is limited to the range disclosed.
Fig. 1 is please referred to, is the establishment step process for being painted the foot deformity detection model 100 of an embodiment of the present invention Figure.The establishment step of foot deformity detection model 100 includes step 110, step 120, step 130 and step 140.
Step 110 is to obtain one referring to information bank, wherein including multiple referring to the inner side of the foot position X-ray image referring to information bank Information.Preferably, the image format above-mentioned referring to the inner side of the foot position X-ray image information can be digital medical image storage standard The image format of agreement (Digital Imaging and Communications in Medicine, DICOM), by each ginseng It is stored according to essential informations such as the inner side of the foot position physiological age information of X-ray image information, gender information referring to the inner side of the foot position X-ray In the shelves head (header) of image information, in favor of subsequent analysis.Preferably, can be wrapped referring to the inner side of the foot position X-ray image information Containing position X-ray image information on the inside of a left foot and a right the inner side of the foot position X-ray image information, to establish left foot and right sufficient foot respectively Deformity is conducive to carry out more accurately foot deformity detection respectively to two foot of left and right referring to information bank.
Step 120 is to carry out an image pre-treatment step, is that each reference foot is adjusted using an image information editor module An image size and an image black white contrast for inside position X-ray image information, to obtain multiple standardization the inner side of the foot positions X-ray Image information.Specifically, image information editor module can be respectively by the shadow of different reference the inner side of the foot position X-ray image information After being adjusted to 1024 pixels (pixel) × 1024 pixel as size, and adjust the gray-scale distribution that its black white contrast is 0 to 255 Image intensity, to reduce the different black and white coloration differences referring between the X-ray image information of the inner side of the foot position and increase image Clarity, in favor of subsequent analysis.In addition, in the step 120, image information editor module can be further to each referring to foot Inside position X-ray image information carries out the processing of image chroma extension.Specifically, image information editor module can calculate each reference The image gray scale degree of the inner side of the foot position X-ray image information, and according to calculated result above-mentioned and sequentially to each referring to the inner side of the foot position The image pixel row, column of X-ray image information fills up color automatically, and each referring to the inner side of the foot position X-ray shadow of grayscale tone will be presented As information is converted to color shades, to increase each information strength referring to the inner side of the foot position X-ray image information, and then promoted subsequent The accuracy of analysis, but the present invention is not limited with the content that preceding description is disclosed with schema.
Step 130 is to carry out a Feature Selection step, is that standardization foot above-mentioned is analyzed using a characteristic selecting module To obtain at least one image feature value after the X-ray image information of inside position.Specifically, foot deformity detection model 100 of the invention Automatically the image information of standardization the inner side of the foot position X-ray image information is analyzed using characteristic selecting module, and automatic Corresponding image feature value is extracted, so as to promoting the foot deformity diagnosis efficiency of foot deformity detection model 100 of the invention.
Step 140 is to carry out a training step, is that at least one image feature value above-mentioned is passed through a convolutional Neural E-learning classifier is trained and reaches convergence, with foot deformity detection model 100, wherein foot deformity detection model 100 It is the foot deformity type and a foot deformity occurrence degree to judge a subject.Preferably, convolutional Neural net above-mentioned Network Study strategies and methods can be Inception-ResNet-v2 convolutional neural networks.Inception-ResNet-v2 convolutional Neural Network is a kind of extensive visual recognition (Large Scale Visual based on ImageNet visible data information library Recognition) convolutional neural networks can effectively expand in such a way that residual error connects (Residual connections) Open up convolutional neural networks training depth, and then make Inception-ResNet-v2 convolutional neural networks in image classification with distinguish Knowing aspect has quite high accuracy rate.
Preferably, foot deformity type above-mentioned can be flexibility flat foot or structural flat foot, and foot deformity above-mentioned Occurrence degree then can be apodia, slight foot deformity, moderate foot deformity or severe foot deformity.Specifically, the foot of normal person A natural arch is presented in bottom, is the arch of foot of sole, when human body is in walking or running, arch of foot can be according to various landform The elastic force and torsion of appropriateness are provided, to achieve the purpose that shock-absorbing and balance.However, the arch of foot of flat foot patient it is very unobvious or There are few arch of foots, stand or put down when it and step on when ground, and the arch of foot of medial plantar will sink and make vola that flat form be presented, It is even smooth in ground, and then influence normal walking, the wherein subcutaneous fat more Zhao Yin of flexibility flat foot thicker in plantar bottom Or more loose foot joint, and structural flat foot is then because of foot caused by joint exception or Surrounding muscles spasm The hard phenomenon in portion.In the X-ray image information of the sufficient side of standing appearance position, its calcaneum of the splayfooted patient of hbm structure (calcaneus) the angle arch of foot angle (arch angle) of most lower edge line and fifth metatarsal bone (5th metatarsal) are big Flat foot is regarded as when 168 degree, and foot deformity detection model 100 of the invention then can be automatically according to standardization the inner side of the foot position X Optical image information and judge whether subject suffers from flat foot disease and its foot deformity occurrence degree, avoid because of different analysts It is different compare habit and to measure mode different and generate different diagnostic results, and then foot deformity of the invention is made to detect mould The accuracy in detection of type 100 is substantially improved.
A and Fig. 2 B referring to figure 2., Fig. 2A are the framves for being painted the foot deformity detection system 200 of another embodiment of the present invention Structure schematic diagram, Fig. 2 B are the configuration diagrams of the foot deformity detection program 430 for the foot deformity detection system 200 for being painted Fig. 2A.Foot A foot deformity type and a foot deformity occurrence degree of the lopsided detection system 200 to judge a subject, and foot deformity is examined Examining system 200 includes an image acquisition unit 300 and a non-transient machine-readable medium 400.
Target the inner side of the foot position X-ray image information 411 of the image acquisition unit 300 to obtain subject.In detail and Speech, image acquisition unit 300 can be an X-ray check instrument, and the foot of subject is irradiated using the x-ray of low dosage, with Obtain resolution target the inner side of the foot position X-ray image information 411 appropriate.Preferably, target the inner side of the foot position X-ray image information 411 Image format can be digital medical image storage standard agreement image format, by target the inner side of the foot position X-ray image information The essential informations such as 411 physiological age information, gender information are stored in the shelves head of target the inner side of the foot position X-ray image information 411 In, in favor of subsequent analysis.Preferably, target the inner side of the foot position X-ray image information 411 may include position X-ray on the inside of a left foot Image information and a right the inner side of the foot position X-ray image information, in favor of carrying out more accurately foot deformity inspection respectively to two foot of left and right It surveys.
Non-transient 400 signal of machine-readable medium connects image acquisition unit 300, and non-transient machine-readable medium 400 Comprising a storage element 410 and a processing unit 420, wherein storage element 410 is to store target the inner side of the foot position X-ray image Information 411 and a foot deformity detect program 430, and processing unit 420 is to execute foot deformity detection program 430.Foot deformity detection Program 430 includes that a foot deformity detection model establishes subprogram 440 and foot deformity detection subprogram 450.
It includes one referring to 441, one reference image letter of information bank acquirement module that foot deformity detection model, which establishes subprogram 440, Cease editor module 442, a characteristic selecting module 443 and a training module 444.
Obtaining module 441 referring to information bank is to obtain one referring to information bank, wherein above-mentioned include referring to information bank Multiple reference the inner side of the foot position X-ray image information.Preferably, the image format above-mentioned referring to the inner side of the foot position X optical image information can For the image format of digital medical image storage standard agreement, by each physiological age referring to the inner side of the foot position X-ray image information The essential informations such as information, gender information are stored in the shelves head referring to the inner side of the foot position X-ray image information, in favor of subsequent point Analysis.Preferably, may include position X-ray image information and a right the inner side of the foot position on the inside of a left foot referring to the inner side of the foot position X-ray image information X-ray image information, to establish left foot and right sufficient foot deformity respectively referring to information bank, in favor of carrying out respectively to two foot of left and right More accurately foot deformity detects.
Referring to image information editor module 442 be adjustment it is each referring to the inner side of the foot position X-ray image information an image size and One image black white contrast, to obtain multiple standardization the inner side of the foot positions X-ray image information.Specifically, it is compiled referring to image information 1024 pixel × 1024 can be adjusted to for the different image sizes referring to the inner side of the foot position X-ray image information respectively by collecting module 442 After pixel, and the image intensity for the gray-scale distribution that its black white contrast is 0 to 255 is adjusted, it is different referring to the inner side of the foot position to reduce The clarity of black and white coloration difference and increase image between X-ray image information, in favor of subsequent analysis.In addition, reference Image information editor module 442 further can carry out the processing of image chroma extension referring to the inner side of the foot position X-ray image information to each. Specifically, image information editor module can calculate it is each referring to the inner side of the foot position X-ray image information image gray scale degree, and according to Color is sequentially filled up automatically to each image pixel row, column referring to the inner side of the foot position X-ray image information according to calculated result above-mentioned Coloured silk will be presented each of grayscale tone and be converted to color shades referring to the inner side of the foot position X-ray image information, each referring to foot to increase The information strength of inside position X-ray image information, and then promote the accuracy of subsequent analysis.
Characteristic selecting module 443 be to analytical standard the inner side of the foot position X-ray image information after at least one reference Image feature value.Specifically, the image that characteristic selecting module 443 can automatically to standardization the inner side of the foot position X-ray image information Information is analyzed, and automatically extracts corresponding image feature value.
Training module 444 is at least one to be classified referring to image feature value by a convolution neural network learning Device is trained and reaches convergence, to obtain a foot deformity detection model.Preferably, convolutional neural networks learning classification above-mentioned Device can be Inception-ResNet-v2 convolutional neural networks, effectively to extend the training depth of convolutional neural networks, in turn The image classification and identification capability of training for promotion module 444.
It includes a target image information editing module 451, target signature selection module that foot deformity, which detects subprogram 450, 452 and a comparison module 453.
Target image information editing module 451 is to adjust an image size of target the inner side of the foot position X-ray image information 411 And an image black white contrast, to obtain a standardization target the inner side of the foot position X-ray image information.Specifically, target image is believed Breath editor module 451 is that the image size of target the inner side of the foot position X-ray image information 411 is adjusted to 1024 pixels × 1024 pictures After element, and the image intensity for the gray-scale distribution that its black white contrast is 0 to 255 is adjusted, and then obtains standardization target above-mentioned The inner side of the foot position X-ray image information.Preferably, target image information editing module 451 can be further to target the inner side of the foot position X-ray Image information 411 carries out the processing of image chroma extension, is the image ash for calculating target the inner side of the foot position X-ray image information 411 Rank degree, and according to calculated result above-mentioned and sequentially to the image pixel row, column of target the inner side of the foot position X-ray image information 411 Automatically color is filled up, the target the inner side of the foot that grayscale tone is presented position X-ray image information 411 is converted into color shades, to increase Add the information strength of target the inner side of the foot position X-ray image information, and the shadow with each reference the inner side of the foot position above-mentioned X-ray image information As format is consistent, and then promote the accuracy of subsequent analysis.
Target signature choose module 452 be to analytical standard target the inner side of the foot position X-ray image information after at least One target image characteristic value.Specifically, target signature selection module 452 can be automatically to standardization target the inner side of the foot position X The image information of optical image information is analyzed, and automatically extracts corresponding image feature value.
Comparison module 453 be at least one target image characteristic value to be analyzed with foot deformity detection model, with A target image characteristic value weighted data is obtained, and analyzes target image characteristic value weighted data, to obtain the foot deformity class of subject Type and foot deformity occurrence degree.
Preferably, foot deformity type above-mentioned can be flexibility flat foot or structural flat foot, and foot deformity above-mentioned Occurrence degree then can be apodia, slight foot deformity, moderate foot deformity or severe foot deformity, but the present invention not as Limit.
It referring to figure 3., is the step flow chart for being painted the foot deformity detection method 500 of another embodiment of the present invention. Foot deformity detection method 500 includes step 510, step 520, step 530, step 540 and step 550.
Step 510 is to provide foot deformity detection model, and foot deformity detection model is via abovementioned steps 110 to step 140 are established.
Step 520 is to provide the target the inner side of the foot position X-ray image information of subject.Preferably, target the inner side of the foot position X The image format of optical image information can be the image format of digital medical image storage standard agreement, by target the inner side of the foot position X The essential informations such as the physiological age information of optical image information, gender information are stored in the shelves of target the inner side of the foot position X-ray image information In head, in favor of subsequent analysis.Preferably, target the inner side of the foot position X-ray image information may include position X-ray shadow on the inside of a left foot As information and a right the inner side of the foot position X-ray image information, in favor of carrying out more accurately foot deformity detection respectively to two foot of left and right.
Step 530 is to carry out pre-treatment to target the inner side of the foot position X-ray image information, is to utilize image information editor mould Block adjusts an image size and an image black white contrast for target the inner side of the foot position X-ray image information, to obtain a standardization mesh Mark the inner side of the foot position X-ray image information.Specifically, target image information editing module is by target the inner side of the foot position X-ray image letter After the image size of breath is adjusted to 1024 pixels × 1024 pixels, and adjust the gray-scale distribution that its black white contrast is 0 to 255 Image intensity, and then obtain standardization target the inner side of the foot above-mentioned X-ray image information.Preferably, target image information is compiled Collecting module further can carry out the processing of image chroma extension to target the inner side of the foot position X-ray image information, be to calculate target foot The image gray scale degree of inside position X-ray image information, and according to calculated result above-mentioned and sequentially to target the inner side of the foot position X-ray The image pixel row, column of image information fills up color automatically, and the target the inner side of the foot position X-ray image letter of grayscale tone will be presented Breath is converted to color shades, to increase the information strength of target the inner side of the foot position X-ray image information, and then promotes subsequent analysis Accuracy.
Step 540 be using characteristic selecting module analytical standard target the inner side of the foot position X-ray image information after at least One image feature value.Specifically, foot deformity detection method 500 can be using characteristic selecting module automatically to standardization mesh The image information of mark the inner side of the foot position X-ray image information is analyzed, and automatically extracts corresponding image feature value, so as to promoting The foot deformity diagnosis efficiency of foot deformity detection method 500 of the invention.
Step 550 is to analyze at least one image feature value using foot deformity detection model, to judge the foot of subject Lopsided type and a foot deformity occurrence degree.
According to above embodiment, specific test example set forth below simultaneously cooperates schema to be described in detail.
<test example>
One, referring to information bank
Reference information bank used in the present invention is TaiWan, China hospital general (Taichung Armed Forces General Hospital) backtracking collected go connectionization subject clinical the inner side of the foot position X-ray image information, be Through China Medical University and set up the clinical test meter that region examination board checks and approves in the research ethics committee, hospital It draws, number are as follows: CRREC-107-079.Reference the inner side of the foot position X-ray above-mentioned referring to information bank comprising 6000 subjects Image information, and the image format above-mentioned referring to the inner side of the foot position X-ray image information is all digital medical image storage standard association Fixed image format, by related letters such as the physiological age information of each subject, gender information, case history number, tested numbers Breath is stored in the shelves head of image information, in favor of subsequent analysis.
In addition, referring to foot when it shoots referring to the inner side of the foot position X-ray image information of every subject in information bank Placement position and placing direction are all consistent, and each the inner side of the foot position X-ray image information includes position X-ray image information on the inside of a left foot And a right the inner side of the foot position X-ray image information, to exclude to invert (Random Horizontal using Random Level Inversion), the modes such as the information augments such as random translation (Random Translation), rotation, shearing processing are to left and right Two foots carry out the analysis of foot deformity, and then improve foot deformity detection model of the invention, foot deformity detection system and foot deformity inspection The analysis accuracy rate of survey method.
Two, foot deformity detection model of the invention
For foot deformity detection model of the invention after obtaining referring to information bank, each reference the inner side of the foot position X-ray image information will It is adjusted using an image information editor module, each image size referring to the inner side of the foot position X-ray image information is adjusted to 1024 pixels × 1024 pixels, and the image intensity for the gray-scale distribution that its black white contrast is 0 to 255 is adjusted, to reduce difference Referring to the clarity of black and white coloration difference and increase image between the X-ray image information of the inner side of the foot position, and further to each ginseng Color is filled up automatically according to the image pixel row, column of the inner side of the foot position X-ray image information, and each referring to foot of grayscale tone will be presented Inside position X-ray image information is converted to color shades, and obtains multiple standardization the inner side of the foot positions X-ray image information.
Specifically, since current deep neural network model operationally needs a large amount of training information (Training Data, i.e., foot deformity detection model of the invention referring to the inner side of the foot position X-ray image information) reaches stabilization The classification accuracy of convergence and height is intended if the number of training information not enough abundance will be such that deep neural network generated Close phenomenon (Overfitting) and cause the error amount of judging result excessively high, cause the confidence level of deep neural network model compared with It is low.In order to solve foregoing problems, foot deformity detection model of the invention is by image pre-treatment step to each referring to the inner side of the foot position X-ray image information carries out information augments (Data Augmentation), with each referring to the inner side of the foot position X-ray image by changing The geometric size of information, image intensity are distributed and are added the mode of noise to reduce the Probability of over-fitting, make it Each raw information referring to the inner side of the foot position X-ray image information can also be retained while increasing image information data.
Then, respectively standardization the inner side of the foot position X-ray image information will be analyzed with characteristic selecting module, to obtain at least one A image feature value.Specifically, characteristic selecting module can be distinguished further in the X-ray image information of each standardization the inner side of the foot position Bony areas and background area, and the X-ray image information in analyzing bone region and obtain each standardization the inner side of the foot position X-ray Image feature value in image information.
Then, image feature value above-mentioned will be trained by a convolution neural network learning classifier reaches receipts It holds back, to obtain foot deformity detection model of the invention.In this test example, foot deformity detection model will be applied to judge foot deformity Flexibility flat foot or structural flat foot in type, and the flat foot of subject is further exported based on the analysis results Foot deformity occurrence degree judging result.
It referring to figure 4., is the convolutional neural networks Study strategies and methods 600 for being painted foot deformity detection model of the invention Configuration diagram.In the test example of Fig. 4, convolutional neural networks Study strategies and methods 600 are Inception-ResNet-v2 Convolutional neural networks, it includes multiple convolutional layers (Convolution), multiple maximum pond layers (MaxPool), multiple average Pond layer (AvgPool) and multiple cascading layers (Concat), image feature value is trained and be analyzed.
Specifically, Inception-ResNet-v2 convolutional neural networks are based on ImageNet visible data information The extensive visual recognition convolutional neural networks in library, and the image information inside ImageNet visible data information library is all Two-dimensional color image, therefore existing known GoogLeNet convolutional neural networks model has in its first convolutional layer The filter of RGB triple channel.However, each raw video archives referring to the inner side of the foot position X-ray image information are all three-dimensional grayscale Image is with foot deformity detection model of the invention further by the GoogLeNet convolution of the filter comprising RGB triple channel Neural network model is converted to single channel by arithmetic mean method, and by stochastic gradient descent method (Stochastic Gradient Descent, SGD) it is applied in the pre-training Model Neural of foot deformity detection model of the invention, with excellent Change its training process, frequency of training can be the gradient descent method of 100 phases (Epochs) and 96 Mini-Batch Size of use, And by changing initial learning rate (Learning Rates) to carry out modulation, wherein learning rate is instructed to neural network The important parameter of control weight (weight) and deviation (bias) variation when practicing, is logical with foot deformity detection model of the invention The numerical value for crossing adjustment learning rate can be further assured that loss function (Loss Function) up to stable convergence.
During foot deformity detection model of the invention is trained image feature value, the inner side of the foot is respectively standardized The image feature value of position X-ray image information carries out two layers of convolutional layer and one layer of maximum pond layer (MaxPool) is handled, by institute The image feature value of extraction carries out maximum output, and repeats two layers of convolutional layer above-mentioned and one layer of maximum pond layer output again Afterwards, parallel tower (parallel towers) training is carried out using multiple convolutional layers, to complete the elementary training of image feature value (Inception)。
After completing elementary training above-mentioned, each image feature value for standardizing the inner side of the foot position X-ray image information will be carried out The residual error of 10 times (10 ×), 20 times (20 ×) and the different depth of 10 times (10 ×), different estate and different aspects (Residual) module training is trained and is reached with the image feature value to each standardization the inner side of the foot position X-ray image information Convergence.Specifically, since Inception-ResNet convolutional neural networks are after the weight operation by multiple stratum, because Is carried out by different operation and is sentenced for the image feature value of each standardization the inner side of the foot position X-ray image information for each residual error module It is disconnected, cause error accumulation, therefore the training of Inception-ResNet convolutional neural networks will transport the node of specific stratum The input terminal that calculation value is withdrawn into the stratum carries out operation again, to prevent convolutional neural networks Study strategies and methods 600 to above-mentioned The degradation phenomena that gradient disappears occurs after training for the weight operation that image feature value carries out multilayer, and error accumulation is avoided to lead It causes information to lose, and can effectively promote the training effectiveness of convolutional neural networks Study strategies and methods 600.
It, will be sequentially with one layer of convolutional layer, average a pond layer, one after completing deep layer and the training of duplicate residual error module Replace global average pond layer (Global Average Pooling 2D, GloAvePool2D) and a line rectification unit Training layer (Rectified Linear Unit, ReLU) carries out final training and processing to convergent image feature value, so as to Judge the flat foot occurrence type and flat foot occurrence degree of subject.Wherein, average pond layer can be first to completion residual error mould The image feature value of block training is calculated, and in the hope of the average value of each image feature value, global average pond layer is replaced then may be used Regularization (Regularization) processing is carried out to the overall network framework of convolutional neural networks Study strategies and methods 600, is prevented Under the training mode for pursuing low error over-fitting occurs for convolutional neural networks Study strategies and methods 600, and judgement is caused to be tied The error amount of fruit is excessively high, finally, line rectification module training layer then further swashs the image feature value completed after training It is living, and a target image characteristic value weighted data 601 is exported, to carry out subsequent comparison and analysis.Line rectification above-mentioned Module training layer can avoid foot deformity detection model output target image characteristic value weighted data 601 level off to zero or approach In infinity, in favor of the subsequent progress for comparing step, and then the accuracy of judgement of foot deformity detection model of the invention is promoted Rate.
Then, the flat foot occurrence type of aforementioned subject and flat foot occurrence degree judging result will be further whole Together in referring in information bank, to optimize to foot deformity detection model of the invention, and then detect foot deformity of the invention The training effect and accuracy of judgement degree of model are further promoted.
By above content it is found that foot deformity detection model, foot deformity detection system and foot deformity detection method pass through by The inner side of the foot position X-ray image information and target the inner side of the foot position X-ray image information carry out image and standardize pre-treatment, and utilize feature After choosing module analysis and obtaining at least one image feature value, then with convolutional neural networks Study strategies and methods to image feature value Be trained, whether quickly and accurately to judge that the foot deformity of subject occurs, foot deformity type and foot deformity journey occurs Degree, and the detection reproducibility with height.Furthermore mould is detected by the inclusion of the foot deformity of convolutional neural networks Study strategies and methods Type can effectively promote accuracy and the susceptibility of foot deformity detection, make foot deformity detection model of the invention, foot deformity detection System and foot deformity detection method can provide instant and accurate foot deformity detection in the case of a large amount of X-ray image information Assessment result makes it have excellent clinical application potentiality using the foundation as the monitoring of the subsequent state of an illness or curative effect evaluation.
Although the present invention is disclosed above with embodiment, however, it is not to limit the invention, any to be familiar with this skill Person, without departing from the spirit and scope of the present invention, when can be used for a variety of modifications and variations, therefore protection scope of the present invention Subject to view claim institute defender.

Claims (18)

1. a kind of foot deformity detection model, which is characterized in that the foot deformity detection model is with the foundation of following establishment steps:
One is obtained referring to information bank, wherein the reference information bank includes multiple referring to the inner side of the foot position X-ray image information;
An image pre-treatment step is carried out, is to adjust respectively reference the inner side of the foot position X-ray shadow using an image information editor module As the image size and an image black white contrast of information, to obtain multiple standardization the inner side of the foot positions X-ray image information;
A Feature Selection step is carried out, is to analyze standardization the inner side of the foot position X-ray image using a characteristic selecting module to believe To obtain at least one image feature value after breath;And
A training step is carried out, is to carry out at least one image feature value by a convolution neural network learning classifier It trains and reaches convergence, to obtain the foot deformity detection model, wherein the foot deformity detection model is to judge a subject One foot deformity type and a foot deformity occurrence degree.
2. foot deformity detection model according to claim 1, it is characterised in that: the wherein convolutional neural networks learning classification Device is Inception-ResNet-v2 convolutional neural networks.
3. foot deformity detection model according to claim 1, it is characterised in that: wherein the image pre-treatment step is more to each Reference the inner side of the foot position X-ray image information carries out image chroma extension processing.
4. foot deformity detection model according to claim 1, it is characterised in that: wherein described referring to the inner side of the foot position X-ray shadow As the image format that the image format of information is digital medical image storage standard agreement.
5. foot deformity detection model according to claim 1, it is characterised in that: wherein the foot deformity type is that flexibility is flat Flatfoot or structural flat foot.
6. foot deformity detection model according to claim 1, it is characterised in that: wherein the foot deformity occurrence degree is apodia Lopsided, slight foot deformity, moderate foot deformity or severe foot deformity.
7. foot deformity detection model according to claim 1, it is characterised in that: wherein respectively the reference the inner side of the foot position X-ray shadow As information includes position X-ray image information and a right the inner side of the foot position X-ray image information on the inside of a left foot.
8. a kind of foot deformity detection system, to judge the foot deformity type and a foot deformity occurrence degree of a subject, It is characterized in that, the foot deformity detection system includes:
One image acquisition unit, to obtain the target the inner side of the foot position X-ray image information of the subject;And
One non-transient machine-readable medium, signal connects the image acquisition unit, and the non-transient machine-readable medium includes one Storage element and a processing unit, wherein the storage element is abnormal to store target the inner side of the foot position X-ray image information and a foot Shape detects program, and the processing unit is to execute foot deformity detection program;
Wherein, foot deformity detection program includes:
One foot deformity detection model establishes subprogram, includes:
One obtains module referring to information bank, is to obtain one referring to information bank, wherein the reference information bank includes multiple ginsengs According to the inner side of the foot position X-ray image information;
One referring to image information editor module, be adjust a respectively image size of reference the inner side of the foot X-ray image information and One image black white contrast, to obtain multiple standardization the inner side of the foot positions X-ray image information;
One characteristic selecting module, be to analyze after the X-ray image information of standardization the inner side of the foot position at least one ginseng According to image feature value;And
One training module is to pass through a convolution neural network learning classifier at least one reference image feature value by this It is trained and reaches convergence, to obtain a foot deformity detection model;And
One foot deformity detects subprogram, includes:
One target image information editing's module is the image size and one for adjusting target the inner side of the foot position X-ray image information Image black white contrast, to obtain a standardization target the inner side of the foot position X-ray image information;
One target signature choose module, be to analyze the standardization target the inner side of the foot position X-ray image information after at least One target image characteristic value;And
One comparison module, be at least one target image characteristic value to be analyzed with the foot deformity detection model, To obtain a target image characteristic value weighted data, and the target image characteristic value weighted data is analyzed, to obtain being somebody's turn to do for the subject Foot deformity type and the foot deformity occurrence degree.
9. foot deformity detection system according to claim 8, it is characterised in that: the wherein convolutional neural networks learning classification Device is Inception-ResNet-v2 convolutional neural networks.
10. foot deformity detection system according to claim 8, it is characterised in that: wherein reference image information editor's mould Block more carries out image chroma extension processing, target image information editing's mould to respectively reference the inner side of the foot position X-ray image information Block more carries out image chroma extension processing to target the inner side of the foot position X-ray image information.
11. foot deformity detection system according to claim 8, it is characterised in that: wherein target the inner side of the foot position X-ray image The image format of information is the image format of digital medical image storage standard agreement, described referring to the inner side of the foot position X-ray image letter The image format of breath is the image format of digital medical image storage standard agreement.
12. foot deformity detection system according to claim 8, it is characterised in that: wherein the foot deformity type is flexibility Flat foot or structural flat foot.
13. foot deformity detection system according to claim 8, it is characterised in that: wherein the foot deformity occurrence degree is nothing Foot deformity, slight foot deformity, moderate foot deformity or severe foot deformity.
14. foot deformity detection system according to claim 8, it is characterised in that: wherein respectively the reference the inner side of the foot position X-ray shadow As information includes position X-ray image information and a right the inner side of the foot position X-ray image information, target the inner side of the foot position X-ray on the inside of a left foot Image information includes position X-ray image information and a right the inner side of the foot position X-ray image information on the inside of a left foot.
15. a kind of foot deformity detection method, characterized by comprising:
One foot deformity detection model as claimed in claim 1 is provided;
The target the inner side of the foot position X-ray image information of one subject is provided;
Pre-treatment is carried out to target the inner side of the foot position X-ray image information, is to adjust the mesh using the image information editor module An image size and an image black white contrast for the inner side of the foot position X-ray image information is marked, to obtain a standardization target the inner side of the foot Position X-ray image information;
Using this feature choose after the X-ray image information of module analysis standardization target the inner side of the foot position at least one image is special Value indicative;And
At least one image feature value is analyzed using the foot deformity detection model, to judge the foot deformity type of the subject An and foot deformity occurrence degree.
16. foot deformity detection method according to claim 15, it is characterised in that: wherein the image information editor module is more The processing of one image chroma extension is carried out to target the inner side of the foot position X-ray image information.
17. foot deformity detection method according to claim 15, it is characterised in that: wherein target the inner side of the foot position X-ray shadow As the image format that the image format of information is digital medical image storage standard agreement.
18. foot deformity detection method according to claim 15, it is characterised in that: wherein target the inner side of the foot position X-ray shadow As information includes position X-ray image information and a right the inner side of the foot position X-ray image information on the inside of a left foot.
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