CN110262336A - Current output circuit and channel-cranium electro-stimulating device including it - Google Patents

Current output circuit and channel-cranium electro-stimulating device including it Download PDF

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Publication number
CN110262336A
CN110262336A CN201910526149.6A CN201910526149A CN110262336A CN 110262336 A CN110262336 A CN 110262336A CN 201910526149 A CN201910526149 A CN 201910526149A CN 110262336 A CN110262336 A CN 110262336A
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current output
signal
output circuit
branch
current
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CN110262336B (en
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戚自辉
蒋田仔
张玉瑾
余山
刘浩
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Institute of Automation of Chinese Academy of Science
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Institute of Automation of Chinese Academy of Science
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36025External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05BCONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B19/00Programme-control systems
    • G05B19/02Programme-control systems electric
    • G05B19/04Programme control other than numerical control, i.e. in sequence controllers or logic controllers
    • G05B19/042Programme control other than numerical control, i.e. in sequence controllers or logic controllers using digital processors
    • G05B19/0423Input/output
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05BCONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B2219/00Program-control systems
    • G05B2219/20Pc systems
    • G05B2219/21Pc I-O input output
    • G05B2219/21024Analog output
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05BCONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B2219/00Program-control systems
    • G05B2219/20Pc systems
    • G05B2219/21Pc I-O input output
    • G05B2219/21137Analog to digital conversion, ADC, DAC

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Automation & Control Theory (AREA)
  • Child & Adolescent Psychology (AREA)
  • Developmental Disabilities (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Social Psychology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Electrotherapy Devices (AREA)

Abstract

The present embodiments relate to electronic circuit or electrical transcranial stimulation technique field, solve since signal poor synchronization leads to coherent area movement position inaccurate.First aspect of the embodiment of the present invention discloses a kind of current output circuit, including at least two electric currents output branch, reference clock source and external interface, in which: at least two electric currents output branch passes through external interface and is connected to outside source;The control terminal of at least two electric currents output branch is connect with reference clock source signal, so that the current synchronization of at least two electric currents output branch output.The invention has the benefit that the current synchronization of all electric current output branch output;When the current output circuit is used for channel-cranium electro-stimulating device, so that different sites of electrostimulation can be simultaneously by electro photoluminescence, it is accurately positioned conducive to the coherent area movement of the electro photoluminescence different to this, so that electro photoluminescence can accurately be applied to the coherent area movement, guarantees the therapeutic effect of electro photoluminescence.

Description

Current output circuit and channel-cranium electro-stimulating device including it
Technical field
The present invention relates to electronic circuit technology fields, and in particular to a kind of current output circuit and piercing through cranium electricity including it Swash equipment.
Background technique
It is a kind of through cranium microcurrent stimulating therapy (Cranial electrotherapy stimulation, abbreviation CES) The entirely different treatment method with conventional medication, electric convulsions is to stimulate brain by low-intensity micro-current, changes The brain wave of brain in patients exception promotes brain to secrete a series of minds that there are close ties with diseases such as anxiety, depression, insomnias Through mediator and hormone, the treatment to these diseases is realized with this.
The space orientation ability of current traditional channel-cranium electro-stimulating device is weak, stimulates large stretch of brain area, can not be to target brain area Carry out fixed point stimulation.Occurred a kind of technology of relevant electrical transcranial stimulation of new time-frequency in recent years, principle is using in mouse head Epidermis face applies the extremely high frequency electro photoluminescence (such as 2000Hz and 2010Hz) that two-way has very little difference on the frequency, and high frequency stimulation itself is no Any cerebration can be caused to respond, but two paths of signals coherent area movement can produce low frequency stimulating effect (such as 10Hz), pass through The spatial arrangement for adjusting scalp electrode, can successfully induce the cerebration of the coherent area movement, due to the poor synchronization of two paths of signals Lead to the coherent area movement position inaccurate (be embodied in the coherent area movement can there is a phenomenon where drift about).Therefore, it is necessary to one kind Current output circuit and channel-cranium electro-stimulating device including it, to solve or at least mitigate the above problem.
Summary of the invention
In order to solve the above problem in the prior art, in order to solve to cause due to signal poor synchronization coherent area movement fixed The problem of position inaccuracy, first aspect of the embodiment of the present invention provide a kind of current output circuit, including at least two electric currents are defeated Out branch, reference clock source and external interface, in which:
At least two electric currents output branch passes through the external interface and is connected to outside source;
The control terminal of at least two electric currents output branch is connect with the reference clock source signal, so that described At least two electric currents export the current synchronization of branch output.
In some preferred embodiments, each electric current output branch includes sequentially connected master controller, number Analog converter and voltage-controlled current source, in which:
The master controller is all connected with the external interface and the reference clock source, to be based on the external interface The command signal received calculates digital voltage control signal;
The digital analog converter is used to being converted to digital voltage control signal into analog voltage signal and export to institute State voltage-controlled current source;
The analog voltage signal output electric current letter that the voltage-controlled current source is used to export according to the digital analog converter Number, to be formed to the electro photoluminescence through cranium.
In some preferred embodiments, the voltage-controlled current source is finished product module or is built using discrete device.
In some preferred embodiments, the master controller is single-chip microcontroller, and the current output circuit further includes UART letter Number conversion module, the UART signal conversion module are connected to the external interface and at least two electric current output branch Between control terminal.
In some preferred embodiments, the external interface is USB interface, and the UART signal conversion module turns for USB URAT module.
In some preferred embodiments, the UART signal conversion module and the master controller are connected with serial ports isolator Part, for the rs 232 serial interface signal of the UART signal conversion module to be carried out electrical isolation.
In some preferred embodiments, clock isolation device is connected between the reference clock source and the master controller Part, the reference clock signal for providing the reference clock source carry out electrical isolation.To guarantee electrical safety.
In some preferred embodiments, the electric current output branch is two.
Second aspect of the embodiment of the present invention provides a kind of channel-cranium electro-stimulating device, and the channel-cranium electro-stimulating device includes:
Any above-mentioned current output circuit;
Bracket, the current output circuit are installed on the bracket;And
Electro photoluminescence acts on end, and the output end of each electric current output branch is electrically connected at least one electro photoluminescence work With end.
In some preferred embodiments, the channel-cranium electro-stimulating device further includes computer, and the signal of the computer is defeated Outgoing interface is connect with the external interface.
The invention has the benefit that
The control terminal of at least two electric currents output branch is connect with reference clock source signal, so that all electric currents export The current synchronization of branch output;When the current output circuit is used for channel-cranium electro-stimulating device, so that different sites of electrostimulation It can be accurately positioned simultaneously by electro photoluminescence conducive to the coherent area movement of the electro photoluminescence different to this, so that electro photoluminescence can be acted on accurately To the coherent area movement, guarantee the therapeutic effect of electro photoluminescence.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of one embodiment of current output circuit, and it is two that electric current output branch, which is shown, Situation.
In figure:
1, USB interface;2, USB turns UART module;3, reference clock source;
100, the first electric current exports branch;101, first serial isolating device;102, the first clock isolation device;103, One master controller;104, the first digital analog converter;105, the first voltage-controlled current source;
200, the second electric current exports branch;201, second serial isolating device;202, second clock isolating device;203, Two master controllers;204, the second digital analog converter;205, the second voltage-controlled current source.
Specific embodiment
The preferred embodiment of the present invention described with reference to the accompanying drawings.It will be apparent to a skilled person that this A little embodiments are used only for explaining technical principle of the invention, it is not intended that limit the scope of the invention.
Referring to Fig.1, first aspect of the embodiment of the present invention discloses a kind of current output circuit, including at least two electric currents are defeated Out branch, reference clock source 3 and external interface, in which:
At least two electric currents output branch passes through external interface and is connected to outside source;
The control terminal of at least two electric currents output branch is connect with reference clock source signal, so that at least two electric currents Export the current synchronization of branch output.
The control terminal of at least two electric currents output branch is connect with reference clock source signal, so that all electric currents export The current synchronization of branch output;When the current output circuit is used for channel-cranium electro-stimulating device, so that different sites of electrostimulation It can be accurately positioned simultaneously by electro photoluminescence conducive to the coherent area movement of the electro photoluminescence different to this, so that electro photoluminescence can be acted on accurately To the coherent area movement, guarantee the therapeutic effect of electro photoluminescence.
It should be noted that the situation that electric current output branch is two is shown in Fig. 1, if two electric currents export branch Respectively the first electric current exports branch 100 and the second electric current exports branch 200.Those of skill in the art would appreciate that electric current is defeated The quantity that the quantity of out branch can according to need the current signal of output carries out flexible setting, will not enumerate herein.
Those of skill in the art would appreciate that the electric current exports branch, as current source, as long as can be in reference clock source Control under exportable electric current after by the excitation of outside source, its specific structure is not limited.Similarly, setting pair External tapping provides input signal and power supply to export branch at least two electric current, does not limit its specific communication protocol.
In addition, reference clock source can choose active crystal oscillator, those of skill in the art would appreciate that also can be selected Other concrete forms, will not enumerate.
With continued reference to Fig. 1, a kind of specific structure of electric current output branch is that each electric current output branch includes successively connecting Master controller, digital analog converter and the voltage-controlled current source connect, in which:
Master controller is all connected with external interface and reference clock source, to the command signal received based on external interface Calculate digital voltage control signal;
Digital analog converter is used to being converted to digital voltage control signal into analog voltage signal and export to voltage-controlled electricity Stream source;
Voltage-controlled current source is used for the analog voltage signal output current signal exported according to digital analog converter, to be formed To the electro photoluminescence through cranium.
It should be noted that Cortex-m3 Series MCU can be selected in master controller device, it is with interface abundant and relatively strong Computing capability.
Digital analog converter, i.e. DAC (full name in English are as follows: Digital to analog converter) are a kind of incite somebody to action The equipment that digital signal is converted to analog signal (in the form of electric current, voltage or charge).In many digital display circuits (such as count Calculation machine), signal stores and transmits in a digital manner, and such signal can be converted to simulation letter by digital analog converter Number, so that they can be by extraneous (people or other nonnumeric systems) identification, digital analog converter selection common 12 Position or 16 bit digital analog converters, voltage output.
It is built in addition, discrete device also can be used in the module that voltage-controlled current source can choose finished product, selection is flexible.
In addition, master controller is single-chip microcontroller, current output circuit further includes UART signal conversion module, UART signal conversion Module is connected between external interface and the control terminal of at least two electric currents output branch.It will be outer by UART signal conversion module Portion's signal source is converted to the identifiable signal of single-chip microcontroller.
In addition, external interface is usb 1, UART signal conversion module is that USB turns URAT module 2.USB turns UART mould Block can select the USB such as FT232, PL2303, CH340 to turn serial port chip, it is only necessary to seldom peripheral components can realize by Usb signal is converted to UART rs 232 serial interface signal.
In addition, UART signal conversion module and master controller are connected with serial ports isolating device, for converting UART signal The rs 232 serial interface signal of module carries out electrical isolation, to guarantee electrical safety.
In addition, clock isolation device is connected between reference clock source and master controller, for providing reference clock source Reference clock signal carry out electrical isolation.To guarantee electrical safety.Serial ports isolating device and clock isolation device can be adopted With high speed photo coupling, the isolation of electric signal is realized by optical signal.
In Fig. 1, the first electric current exports serial ports isolating device, clock isolation device, the master controller, digital simulation of branch road Converter and voltage-controlled current source are respectively first serial isolating device 101, the first clock isolation device 102, the first master controller 103, the first digital analog converter 104 and the first voltage-controlled current source 105, the electric current of output are i1;Second electric current exports branch On serial ports isolating device, clock isolation device, master controller, digital analog converter and voltage-controlled current source be respectively the second string Mouth isolating device 201, second clock isolating device 202, the second master controller 203, the second digital analog converter 204 and second Voltage-controlled current source 205, the electric current of output are i2
Second aspect of the embodiment of the present invention discloses a kind of channel-cranium electro-stimulating device, and channel-cranium electro-stimulating device includes:
Any above-mentioned current output circuit;
Bracket, current output circuit are installed on bracket, which provides installation base for each component of current output circuit Plinth;And
Electro photoluminescence acts on end, and the output end of each electric current output branch is electrically connected at least one electro photoluminescence effect End, electro photoluminescence effect end should be made of the good conductor (such as copper or silver) of electricity, in use, electro photoluminescence effect end is attached to table Face.
Since channel-cranium electro-stimulating device uses any above-mentioned current output circuit, has any above-mentioned electricity The characteristics of flowing output circuit, can solve identical technical problem and produce identical beneficial effect, be not repeated to illustrate.
In addition, channel-cranium electro-stimulating device further includes computer, the signal output interface of computer is connect with external interface. That is, the outside source of current output circuit is the output signal of computer, it can use the powerful storage of computer, calculate energy Power and the output of stable power supply capacity meet the signal of various requirement, so that channel-cranium electro-stimulating device the operation is stable, reliable And the current signal of a variety of requirements can be exported, to meet multiple use.
It should be noted that in the description of the present invention, term " center ", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outside" etc. indicate that the term of direction or positional relationship is direction based on the figure or positional relationship, this is only It is merely for convenience of describing, rather than indication or suggestion described device or element must have a particular orientation, with specific side Position construction and operation, therefore be not considered as limiting the invention.In addition, term " first ", " second ", " third " are only used for Purpose is described, relative importance is not understood to indicate or imply.
In addition it is also necessary to explanation, in the description of the present invention unless specifically defined or limited otherwise, term " peace Dress ", " connected ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integrally Connection;It can be mechanical connection, be also possible to be electrically connected;Can be directly connected, can also indirectly connected through an intermediary, It can be the connection inside two elements.To those skilled in the art, it can understand that above-mentioned term exists as the case may be Concrete meaning in the present invention.
Term " includes " or any other like term are intended to cover non-exclusive inclusion, so that including a system Process, article or the equipment/device of column element not only include those elements, but also other are wanted including what is be not explicitly listed Element either further includes these processes, article or the intrinsic element of equipment/device.
So far, it has been combined preferred embodiment shown in the drawings and describes technical solution of the present invention, still, this field Technical staff is it is easily understood that protection scope of the present invention is expressly not limited to these specific embodiments.Without departing from this Under the premise of the principle of invention, those skilled in the art can make equivalent change or replacement to the relevant technologies feature, these Technical solution after change or replacement will fall within the scope of protection of the present invention.

Claims (10)

1. a kind of current output circuit, which is characterized in that export branch, reference clock source including at least two electric currents and to external Mouthful, in which:
At least two electric currents output branch passes through the external interface and is connected to outside source;
The control terminal of at least two electric current output branch is connect with the reference clock source signal so that it is described at least The current synchronization of two electric current output branch output.
2. current output circuit according to claim 1, which is characterized in that each electric current output branch include according to Master controller, digital analog converter and the voltage-controlled current source of secondary connection, in which:
The master controller is all connected with the external interface and the reference clock source, to be received based on the external interface The command signal arrived calculates digital voltage control signal;
The digital analog converter is used to being converted to digital voltage control signal into analog voltage signal and export to the pressure Control current source;
The voltage-controlled current source is used for the analog voltage signal output current signal exported according to the digital analog converter, with It is formed to the electro photoluminescence through cranium.
3. current output circuit according to claim 2, which is characterized in that the voltage-controlled current source is finished product module or makes It is built with discrete device.
4. current output circuit according to claim 3, which is characterized in that the master controller is single-chip microcontroller, the electricity Flow output circuit further include UART signal conversion module, the UART signal conversion module be connected to the external interface with it is described At least two electric currents export between the control terminal of branch.
5. current output circuit according to claim 4, which is characterized in that the external interface is USB interface, described UART signal conversion module is that USB turns URAT module.
6. current output circuit according to claim 5, which is characterized in that the UART signal conversion module and the master Controller is connected with serial ports isolating device, for the rs 232 serial interface signal of the UART signal conversion module to be carried out electrical isolation.
7. according to current output circuit described in claim 4,5 or 6, which is characterized in that the reference clock source and the master Clock isolation device is connected between controller, reference clock signal for providing the reference clock source carry out electrically every From.
8. current output circuit according to claim 7, which is characterized in that the electric current output branch is two.
9. a kind of channel-cranium electro-stimulating device, which is characterized in that the channel-cranium electro-stimulating device includes:
Current output circuit described in any item of the claim 1 to 8;
Bracket, the current output circuit are installed on the bracket;And
Electro photoluminescence acts on end, and the output end of each electric current output branch is electrically connected at least one electro photoluminescence effect End.
10. channel-cranium electro-stimulating device according to claim 9, which is characterized in that the channel-cranium electro-stimulating device further includes Computer, the signal output interface of the computer are connect with the external interface.
CN201910526149.6A 2019-06-18 2019-06-18 Current output circuit and transcranial electrical stimulation device comprising same Active CN110262336B (en)

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