CN110251108A - Blood pressure measuring device based on electrocardio and pulse wave acoustic signals - Google Patents

Blood pressure measuring device based on electrocardio and pulse wave acoustic signals Download PDF

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Publication number
CN110251108A
CN110251108A CN201910569805.0A CN201910569805A CN110251108A CN 110251108 A CN110251108 A CN 110251108A CN 201910569805 A CN201910569805 A CN 201910569805A CN 110251108 A CN110251108 A CN 110251108A
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CN
China
Prior art keywords
pulse wave
acoustic signals
acquisition module
wave acoustic
blood pressure
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CN201910569805.0A
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Chinese (zh)
Inventor
王伟彬
周媛
王思淇
刘柱
庄佳奕
王萍
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Shanghai Maritime University
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Shanghai Maritime University
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Priority to CN201910569805.0A priority Critical patent/CN110251108A/en
Publication of CN110251108A publication Critical patent/CN110251108A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/02108Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation

Abstract

The present invention relates to a kind of blood pressure measuring device based on electrocardio and pulse wave acoustic signals, contacts right finger and left hand wrist by the top electrode and lower electrode of electrocardiogram acquisition module to acquire electrocardiogram ECG signal respectively;Wrist is contacted by pulse wave acoustic signals acquisition module to acquire pulse wave acoustic signals;Lower electrode and pulse wave acoustic signals acquisition module are shrouded in the cavity by sound insulation chamber, shield noise jamming;After microprocessor module carries out analog-to-digital conversion to the data of acquisition, it is sent to propagation time PWTT of the time difference between the characteristic point of host computer signal processing module two kinds of signals of calculating as pulse wave, and establish regression equation of the propagation time PWTT to blood pressure of pulse wave, will pass through the propagation time PWTT for the pulse wave that certain measurement obtains, corresponding pressure value is calculated.Structure of the invention is simple, easy to use, and measuring accuracy is high.

Description

Blood pressure measuring device based on electrocardio and pulse wave acoustic signals
Technical field
The present invention relates to Medical Devices field of health care, are related specifically to electrocardio, blood pressure detecting field, realize a kind of base In the blood pressure measuring device of electrocardio and pulse wave acoustic signals.
Background technique
Blood pressure is one of four big vital signs of human body, and clinical trial proves, blood pressure be not only reflection heart and Vascular function state, the important indicator of human recycle system, and diagnose the illness, observe therapeutic effect and monitoring rehabilitation course etc. The important evidence of diagnosis and treatment means.Therefore, the monitoring of blood pressure is of great significance in clinical medicine.Traditional discontinuous measurement side Method can preferably reflect measurement result, and the common mark of clinical and scientific research reference such as Korotkoff's Sound stethoscopy and oscillographic method Standard, but have the disadvantage that artifical influence factor it is more and can only single measurement, do not have real-time monitoring ability.Both blood pressure measurements Process will use inflation cuff to carry out discontinuity inflation, and inflation cuff, cannot since vascular compression can cause discomfort to patient The instant blood pressure of human body is obtained at once, and cannot be measured again at once after measuring once, and it is all inconvenient to use and carry.Therefore It is particularly significant to develop a portable comfortable continuous blood pressure monitoring equipment.
Pulse wave velocity measuring method is there are the characteristics that positive correlation proposed based on pulse wave conduction speed and blood pressure, is led to It crosses pulse wave conduction speed and calculates arterial pressure value indirectly.Pulse wave conduction speed can pass through pulse wave point-to-point transmission in the artery Passing time calculate, therefore same principle can be used and extrapolate pressure value indirectly using pulse wave translation time.
Currently, there are mainly two types of modes for detection pulse wave, one is photoelectric plethysmograph is based on, another kind is based on pressure Force snesor:
First method can easily obtain pulse wave signal, but its only acral a certain blood vessel for measuring Filling degree, that is what it mainly reflected be the blood volume of capillary network variation.Photoelectric plethysmograph Sensitivity is low, is affected by ambient seriously, and by the scattering effect of subdermal tissue and bone.
Second method is very high for the precise requirements of measuring point, and subtle position deviation may influence acquisition Information before detection must be accurately positioned subject's radial artery, this is unfavorable for pulse wave signal and quickly and easily obtains.
Summary of the invention
In order to solve the problems existing in the prior art, the present invention provides a kind of blood pressure measuring device based on electrocardiograph pulse wave, Its is easy to use, and measuring accuracy is high.
In order to achieve the above object, the technical solution of the present invention is to provide a kind of blood based on electrocardio and pulse wave acoustic signals Pressure measuring device includes:
Electrocardiogram acquisition module acquires electrocardiogram ECG signal by the top electrode being equipped with and lower electrode;
Pulse wave acoustic signals acquisition module acquires pulse wave acoustic signals;
Microprocessor module, receive the electrocardiogram acquisition module, the collected data of pulse wave acoustic signals acquisition module into Row A/D analog-to-digital conversion;
Host computer signal processing module receives the data that the microprocessor module is sent to it, by measuring electrocardiogram Propagation time PWTT of the time difference as pulse wave between the R crest value point and the characteristic point of pulse wave acoustic signals of ECG signal.
Optionally, the host computer signal processing module also calculates the propagation time PWTT of blood pressure BP and the pulse wave Between approximate relation are as follows:
BP=a+b × PWTT
Wherein, a, b are two parameters to be measured;
The host computer signal processing module obtains user's respiratory state and changes front and back, is obtained by the blood pressure measuring device The propagation time PWTT of the pulse wave obtained, also acquisition user's respiratory state change front and back and pass through the blood that electronic sphygmomanometer records It presses data to carry out linear fit, to determine parameter a and b, and establishes recurrence of the propagation time PWTT of the pulse wave to blood pressure Equation;
The propagation time PWTT of the pulse wave obtained by any one-shot measurement is provided, the regression equation calculation can be passed through Corresponding pressure value out.
Optionally, the blood pressure measuring device further includes sound insulation chamber, by the lower electrode of the electrocardiogram acquisition module and Pulse wave acoustic signals acquisition module shrouds in the cavity of sound insulation chamber.
Optionally, the sound insulation chamber is double-layer structure, includes the plastic chamber of internal layer and its external sound-proof material adhered to.
Optionally, the interior side contacts of the lower electrode of the electrocardiogram acquisition module and left or right hand wrist, the top electrode It is contacted with any finger of the right hand or left hand, the potential difference between left upper extremity and right upper extremity is obtained by electrocardiogram acquisition module, is turned Get electrocardiogram ECG signal in return;
The electrocardiogram acquisition module also includes the first signal conditioning circuit, is provided with low-pass filter circuit, high-pass filtering Collected electrocardiogram ECG signal is converted to voltage signal required for suitable A/D analog-to-digital conversion by device and amplifying circuit.
Optionally, the pulse wave acoustic signals acquisition module be placed on radial artery on the inside of left or right hand wrist just on Side;The pulse wave acoustic signals acquisition module also includes second signal conditioning circuit, is provided with impedance inverter circuit, low pass filtered Collected pulse wave acoustic signals are converted to voltage signal required for suitable A/D analog-to-digital conversion by wave circuit and amplifying circuit.
Optionally, EPIC sensor is respectively adopted in the top electrode of the electrocardiogram acquisition module and lower electrode;The pulse wave Acoustical signal acquisition module uses electret microphone, and the electret transducer front end is cased with one section of coupler.
Optionally, the blood pressure measuring device is further provided with shell and tabular form device;
By the shell, top electrode and lower electrode, pulse wave acoustic signals acquisition module to the electrocardiogram acquisition module, Microprocessor module is fixed;The host computer signal processing module is arranged other than shell, with the microprocessor module Signal connection;
The tabular form device includes two watchbands for being connected to shell both ends;Several watch buckles of one watchband setting, it is corresponding It is embedded into several grooves of another watchband setting, makes arm of the blood pressure measuring device by tabular form device ring around user After carry out relatively fixed, and then make the lower electrode of the electrocardiogram acquisition module, pulse wave acoustic signals acquisition module respectively from user Data are obtained at wrist.
Optionally, the shell be equipped with intermediate bulkhead, by intermediate bulkhead by the inner space of shell be divided into top and Lower part: the top electrode of the electrocardiogram acquisition module is located at the top of shell, and a part of the top electrode passes through shell and in shell The exposure setting of body surface face;The microprocessor module is located in the top of shell, is carried by intermediate bulkhead;
Lower electrode, the pulse wave acoustic signals acquisition module of the electrocardiogram acquisition module are separately positioned on the lower part of shell;Its In, a part of the lower electrode passes through shell and exposure is arranged on the surface of shell;The pulse wave acoustic signals acquisition module The coupler that is arranged of electret microphone front end some pass through shell and exposure is arranged on the surface of shell;
It is provided with sound insulation chamber below the shell, is looped around the periphery of exposed coupler, lower electrode;The shell into One step includes inner casing and shell, and the shell is made of hard material, and the inner casing is sound-proof material.
Optionally, the microprocessor module receives the acquisition number of electrocardiogram acquisition module, pulse wave acoustic signals acquisition module After being handled, host computer signal processing module is sent to by bluetooth;
The blood pressure measuring device further includes battery powered power supply module, respectively ecg signal acquiring mould Block, pulse wave acoustic signals acquisition module and microprocessor module power supply;The host computer signal processing module passes through 220V alternating current Power supply.
Blood pressure test device of the invention, in such a way that EGC sensor and electret microphone acquire jointly, simultaneously Obtain the electrocardiosignal and pulse voice signal at radial artery.Electrocardiogram acquisition module and pulse wave acoustic signals acquisition module are solid respectively It is scheduled on the lower part of shell, is connect by modes such as data lines with microprocessor module and carries out data processing, easy to use, measurement essence Exactness is high, can also further connect with smart machines such as mobile phone, computers and carry out subsequent data analysis.
Compared with prior art, blood pressure measuring device of the invention, the advantage is that:
1, the present invention uses contactless electret microphone pick pulse wave signal, and structure is simple, high sensitivity, is not required to outer Hyper polarization voltage.
2, the present invention utilizes PWTT data (propagation time of pulse wave), for the first time believes EPIC ECG detecting and pulse wave sound Number detection is integrated in a small-sized watch style device, easy to use.Right finger need to only be touched when needing to measure blood pressure It to top electrode or is placed near top electrode, can start to measure.
3, using sound insulation chamber, form one section of relatively quiet cavity, two kinds of sensors be isolated from the outside world, can obtain by The smaller signal of noise jamming, is more advantageous to the signal processing in later period.
4, the present invention changes the acquisition of PWTT data and blood pressure measurement that front and back carries out using human body respiration state, to change quilt The pressure value of tester can make PWTT and blood pressure in a short time while change, very fast to realize between PWTT and blood pressure Fitting, final realize estimate pressure value by measuring PWTT indirectly, improve detection continuation degree accuracy.
Detailed description of the invention
Fig. 1 is the schematic diagram of the interior outer double-layer structure of heretofore described sound insulation chamber.
Fig. 2 is the structural schematic diagram of blood pressure measuring device of the present invention.
Fig. 3 is the working principle block diagram of blood pressure measuring device of the present invention.
Specific embodiment
Cooperation referring to fig. 2, shown in Fig. 3, blood pressure measuring device of the invention, the pulse based on electrocardio and pulse wave acoustic signals Wave conduction time measures, which includes the top electrode 7 and lower electrode 8, pulse wave sound of electrocardiogram acquisition module Signal acquisition module 3, power supply module 6, sound insulation chamber 13, microprocessor module 4, host computer signal processing module.
Wherein, the sound insulation chamber 13 shrouds the lower electrode 8 of electrocardiogram acquisition module and pulse wave acoustic signals acquisition module 3 In the cavity, to reduce influence of the outside noise to signal acquisition;The microprocessor module 4 receives the upper of electrocardiogram acquisition module The data of electrode 7 and lower electrode 8 and pulse wave acoustic signals acquisition module 3, and send it to host computer signal processing module.
Preferably, EPIC sensor is respectively adopted in the top electrode 7 of the electrocardiogram acquisition module and lower electrode 8;Pulse wave sound Signal acquisition module 3 uses electret microphone.Wherein, before the electret transducer of the pulse wave acoustic signals acquisition module 3 End, is cased with one section of coupler 9.The sound insulation chamber 13 is double-layer structure (Fig. 1), and internal layer is plastic material, and outer layer is sound-proof material.Institute The microprocessor module 4 stated can be by the top electrode 7 of electrocardiogram acquisition module and lower electrode 8 and pulse wave acoustic signals acquisition module 3 The signal of input is sent to host computer signal processing module after treatment, with bluetooth approach.Host computer signal processing module can To be arranged in the smart machines such as mobile phone, computer, but not limited to this.
Preferred measuring device is additionally provided with shell and tabular form device, and the tabular form device includes two tables connected to the housing Band;Several watch buckles 11 of one watchband setting, can be correspondingly embedded in several grooves 10 of another watchband setting, make the survey Amount device ring can be fixed after the arm 12 of user, enable lower electrode 8, the pulse wave acoustic signals of the electrocardiogram acquisition module Acquisition module 3 can carry out data from the corresponding site of user's wrist respectively and acquire (described below).
The shell of this example further includes inner casing 1 and shell 2, which is made of plastics or other hard materials, rises solid It is set for using;The inner casing 1 is sound insulation cotton material, and the two further functions as the effect of block external acoustical noise.By intermediate bulkhead by shell The inside of body is divided into two parts up and down;The top electrode 7 of electrocardiogram acquisition module is embedded on the top of shell, passes through 1 He of inner casing A part of the top electrode 7 is arranged in surface of shell (such as upper surface) exposure in shell 2.Microprocessor module 4 is arranged in shell Top in, can be carried by intermediate bulkhead.Lower electrode 8, pulse wave acoustic signals acquisition module 3, the electricity of the electrocardiogram acquisition module Source power supply module 6 is separately fixed at the lower part of shell, installs to the lower plate 5 of shell.Wherein, lower electrode 8 some pass through Inner casing 1 and shell 2, and be arranged in the surface of shell (such as lower surface) exposure;Pulse wave acoustic signals acquisition module 3 passes through its electret The coupler 9 that body microphone front end is arranged pass through inner casing 1 and shell 2, make a part of the coupler 9 the surface of shell (such as Lower surface) exposure setting.The lower section of the shell is arranged in sound insulation chamber 13, and is looped around the periphery of coupler 9, lower electrode 8.
In above-mentioned test device of the invention, electrocardiogram acquisition module selects the EPIC sensor of two pieces of placements symmetrical above and below, It can be with high-acruracy survey electrocardiogram ECG.Conventional contact electrode is carried out by the ion on the electrolyte and skin in electrode Redox reaction generates equivalent potential value.It is different from traditional electrode, EPIC sensor using capacitive coupling principle, True current path can be not present by being capacitively coupled to electrode plate in the electric field potential of skin between sensor and skin, With very high input impedance, small electric field change can detecte.Wherein, lower electrode 8 is placed on the inside of left hand wrist, when need When measuring electrocardiogram ECG, any finger of the right hand is placed in top electrode 7 and is kept in contact, electrocardiogram acquisition module is just opened at this time Beginning work.I lead of standard for medically measuring electrocardiogram is at this time just constituted, lower electrode 8 makees anode, and top electrode 7 makees cathode, What the electrocardiogram measured reacted is the potential difference between left upper extremity and right upper extremity.Referring to Fig. 3, electrocardio is collected from human body wrist After figure ECG signal, is obtained by signal conditioning circuit and A/D is suitble to convert required voltage signal.Signal conditioning circuit is equipped with low Bandpass filter circuit, high-pass filter and amplifying circuit: low-pass filter circuit, high-pass filter collectively constitute a bandpass filtering Device, for filtering out the noise unrelated with signal, including low frequency and high-frequency interferencing signal, while improving the signal-to-noise ratio of signal, Inhibit the drift of the signal base line as caused by human motion etc.;The effect of amplifying circuit is to amplify collected signal amplitude simultaneously Match with the input range of A/D converter.
The pulse wave acoustic signals acquisition module 3 is placed on the surface of radial artery on the inside of left hand wrist, adopts with electrocardio The lower electrode 8 for collecting module is placed side by side.Pulse wave acoustic signals acquisition module 3 mainly includes electret microphone, coupler 9, letter Number conditioning circuit.Electret microphone is a kind of miniature acoustic-electrical transducer, it is with the electret for having been injected into charge in advance and being polarized Body material replace polarizing voltage, for voice signal is changed into electric signal, have many advantages, such as structure simply, high sensitivity.For Precise measurement pulse wave voice signal, the present invention acquire pulse voice signal using " INDIRECT COUPLING mode ", i.e. microphone is matched It closes coupler 9 to use, in the cylindrical coupler in fixed one of the front end of microphone, keeps microphone not in direct contact with the skin, it Between formed air vibration chamber, be convenient for diaphragm of microphone pickoff signals.After collecting pulse wave acoustic signals from human body wrist, Being obtained by signal conditioning circuit is suitble to A/D to convert required voltage signal.Signal conditioning circuit mainly includes that impedance converts, is low Three parts of pass filter and main amplification.Impedance inverter circuit is being accessed behind microphone first, it is transaudient for amplifying electret The collected voltage signal of device.Secondly access low-pass filter circuit, for filtering out the noise signal that extraneous and sensor generates.Most After access amplifying circuit, collected signal amplitude is amplified and is matched with the input range of A/D converter.
The sound insulation chamber 13 can shroud the lower electrode 8 of electrocardiogram acquisition module and pulse wave acoustic signals acquisition module 3 In the cavity, the relatively small number of environment of noise is formed, to reduce the shadow of electrocardio and pulse sound acquisition of the noise to device It rings, improves the precision of device measurement.Sound insulation chamber 13 is double-layer structure, and inside is a plastic chamber, plays fixed function, and outer One layer of sound-proof material is adhered in portion, plays reduction function of noise.
The pulse wave sound that microprocessor module 4 respectively obtains pulse wave acoustic signals acquisition module 3 and electrocardiogram acquisition module Signal and core signal ECG carry out A/D analog-to-digital conversion, and send the digital signal after conversion at host computer signal through bluetooth Manage module.
Power supply system includes battery powered power supply module 6 and 220V alternating current;Wherein, power supply module 6 passes through Battery, respectively ecg signal acquiring module, pulse wave acoustic signals acquisition module 3 and microprocessor module 4 are powered;The 220V Alternating current is used to power to host computer signal processing module.
The host computer signal processing module receives the ECG signal that microprocessor module 4 sends over and pulse wave sound letter After number, it can be further filtered, then the display pulse wave in the display device (such as computer screen) being connected The waveform of acoustical signal and PPG signal, while the characteristic value point of Calling MATLAB algorithm detection two paths of signals, calculate between two o'clock Time difference is PWTT and stores, and carries out line to obtained PWTT data and by the blood pressure data of electronic sphygmomanometer record Property regression analysis, determine relevant parameter, establish PWTT to the equation of linear regression of blood pressure, so as to by corresponding to actual measurement knot The PWTT of fruit estimates blood pressure.
Above-mentioned blood pressure measuring device is when in use:
Tabular form device is worn on the inside of left hand wrist, the coupler 9 in pulse wave acoustic signals acquisition module 3 is in radial artery Surface, while tightening the watchband at tabular form device both ends, watch buckle 11 tipped in corresponding recesses 10, guarantee that device is in one Relatively-stationary state.
Right finger is contacted into top electrode 7, passes through 3 synchronous acquisition of electrocardiogram acquisition module and pulse wave acoustic signals acquisition module Pulse wave acoustic signals at electrocardio ECG and left hand radial artery change the state of testee after a period of time, i.e. measured carries out It deeply breathes, acquires two paths of signals again, and microprocessor module 4 is sent to by signal conditioning circuit.
After collecting electrocardiogram ECG signal, pulse wave acoustic signals, is obtained by signal conditioning circuit be suitble to micro process respectively Device module 4 does voltage signal required for A/D is converted.After microprocessor module 4 carries out respective handling, by two paths of signals through bluetooth Emit to host computer signal processing module.Between R crest value point and the characteristic point of pulse wave acoustic signals by measuring ECG signal Propagation time PWTT of the time difference as pulse wave, by Thomas poplar and Mo Ensi velocity of wave formula obtain blood pressure and PWTT it Between approximate relation are as follows:
BP=a+b × PWTT
Wherein, BP is blood pressure, and a, b are two parameters to be measured:
By carrying out linear fit to obtained PWTT data and by the blood pressure data of electronic sphygmomanometer record, parameter is determined A and b provides PWTT data corresponding with certain measurement, can calculate indirectly to establish PWTT to the regression equation of blood pressure Its corresponding pressure value.
In conclusion above-mentioned relation formula needs determine unknown quantity a and b by two equations, first under steady state An equation is obtained, then using the blood pressure and blood flow state for changing testee of deeply breathing, blood pressure and PWTT value phase can be obtained Another equation that should change, synthesis obtain a, b.
That is, can influence simultaneously blood pressure and PWTT value after adjustment state: intrathoracic pressure power increases when air-breathing, when cardiac ejection Between it is shorter, cardiac output is smaller, and in the case that other conditions are constant, blood pressure is lower correspondingly, and intrathoracic pressure power is smaller when expiration, Ejection time is longer, and cardiac output is bigger, and in the case that other conditions are constant, blood pressure will be increased.
Thus, the data before the present invention changes state are sent to after host computer, and the digital filtering of progress removes high frequency Interference, then it is removed baseline drift processing, finally extracting the time difference between the R crest value of two paths of signals is PWTT;State By similar process after change, obtains new data and handled to obtain new PWTT value.And state changes front and back and all uses Electronic sphygmomanometer recording blood pressure value is transmitted to mated condition in host computer and changes the PWTT value that front and back obtains, and fitting obtains parameter a And b.
Illustratively, the systolic pressure measured before change state using electronic sphygmomanometer is 110mmHg, systolic pressure 76mmHg, The use of the PWTT that the device of the invention measures is 120ms, then can be obtained
110=a+b*120
76=a1+b1*120
If the systolic pressure measured after change state using electronic sphygmomanometer is 120mmHg, systolic pressure 80mmHg, this is used The PWTT that the device of invention measures is 125ms, then can be obtained
120=a+b*125
80=a1+b1*125
Wherein, a and a1 is different numerical value, and b and b1 are also different numerical value;
If the mode averaged, which is fitted, seeks a, and b, precision can be higher by test multi-group data, but at least It needs twice.
It is discussed in detail although the contents of the present invention have passed through above preferred embodiment, but it should be appreciated that above-mentioned Description is not considered as limitation of the present invention.After those skilled in the art have read above content, for of the invention A variety of modifications and substitutions all will be apparent.Therefore, protection scope of the present invention should be limited to the appended claims.

Claims (10)

1. a kind of blood pressure measuring device based on electrocardio and pulse wave acoustic signals, characterized by comprising:
Electrocardiogram acquisition module acquires electrocardiogram ECG signal by the top electrode (7) and lower electrode (8) being equipped with;
Pulse wave acoustic signals acquisition module (3) acquires pulse wave acoustic signals;
Microprocessor module (4) receives the electrocardiogram acquisition module, pulse wave acoustic signals acquisition module (3) collected data Carry out A/D analog-to-digital conversion;
Host computer signal processing module receives the data that the microprocessor module (4) is sent to it, by measuring electrocardiogram Propagation time PWTT of the time difference as pulse wave between the R crest value point and the characteristic point of pulse wave acoustic signals of ECG signal.
2. the blood pressure measuring device based on electrocardio and pulse wave acoustic signals as described in claim 1, which is characterized in that described upper Machine signal processing module also calculates the approximate relation between the blood pressure BP and propagation time PWTT of the pulse wave are as follows:
BP=a+b × PWTT
Wherein, a, b are two parameters to be measured;
The host computer signal processing module obtains user's respiratory state and changes front and back, is obtained by the blood pressure measuring device The propagation time PWTT of the pulse wave, also acquisition user's respiratory state change the blood pressure number that front and back is recorded by electronic sphygmomanometer According to linear fit is carried out, to determine parameter a and b, and regression equation of the propagation time PWTT to blood pressure of the pulse wave is established;
The propagation time PWTT of pulse wave obtained by any one-shot measurement is provided, can be gone out by the regression equation calculation pair The pressure value answered.
3. the blood pressure measuring device based on electrocardio and pulse wave acoustic signals as described in claim 1, which is characterized in that further packet Chamber containing sound insulation (13) shrouds the lower electrode (8) of the electrocardiogram acquisition module and pulse wave acoustic signals acquisition module (3) in sound insulation In the cavity of chamber (13).
4. the blood pressure measuring device based on electrocardio and pulse wave acoustic signals as claimed in claim 3, which is characterized in that the sound insulation Chamber (13) is double-layer structure, includes the plastic chamber of internal layer and its external sound-proof material adhered to.
5. the blood pressure measuring device based on electrocardio and pulse wave acoustic signals as described in claim 1, which is characterized in that the electrocardio The interior side contacts of lower electrode (8) and left or right hand wrist of acquisition module, any of top electrode (7) and the right hand or left hand Finger contact obtains the potential difference between left upper extremity and right upper extremity by electrocardiogram acquisition module, is converted to electrocardiogram ECG letter Number;
The electrocardiogram acquisition module also includes the first signal conditioning circuit, be provided with low-pass filter circuit, high-pass filter and Collected electrocardiogram ECG signal is converted to voltage signal required for suitable A/D analog-to-digital conversion by amplifying circuit.
6. the blood pressure measuring device based on electrocardio and pulse wave acoustic signals as described in claim 1, which is characterized in that the pulse Wave acoustic signals acquisition module (3) is placed on the surface of radial artery on the inside of left or right hand wrist;The pulse wave acoustic signals are adopted Collecting module (3) also includes second signal conditioning circuit, is provided with impedance inverter circuit, low-pass filter circuit and amplifying circuit, Collected pulse wave acoustic signals are converted into voltage signal required for suitable A/D analog-to-digital conversion.
7. the blood pressure measuring device as described in claim 1 or 5 or 6 based on electrocardio and pulse wave acoustic signals, which is characterized in that institute EPIC sensor is respectively adopted in the top electrode (7) and lower electrode (8) for stating electrocardiogram acquisition module;The pulse wave acoustic signals acquire mould Block (3) uses electret microphone, and the electret transducer front end is cased with one section of coupler (9).
8. the blood pressure measuring device as described in claim 1 or 5 or 6 based on electrocardio and pulse wave acoustic signals, which is characterized in that into One step is equipped with shell and tabular form device;
By the shell, top electrode (7) and lower electrode (8), pulse wave acoustic signals to the electrocardiogram acquisition module acquire mould Block (3), microprocessor module (4) are fixed;The host computer signal processing module is arranged other than shell, with micro- place Manage the connection of device module (4) signal;
The tabular form device includes two watchbands for being connected to shell both ends;Several watch buckles (11) of one watchband setting, it is corresponding It is embedded into several grooves (10) of another watchband setting, makes the blood pressure measuring device by tabular form device ring around user's Arm (12) carries out relatively fixed afterwards, and then makes the lower electrode (8) of the electrocardiogram acquisition module, pulse wave acoustic signals acquisition module (3) data are obtained from user's wrist respectively.
9. the blood pressure measuring device based on electrocardio and pulse wave acoustic signals as claimed in claim 8, which is characterized in that the shell Equipped with intermediate bulkhead, the inner space of shell is divided by upper and lower part by intermediate bulkhead: the electrocardiogram acquisition module Top electrode (7) is located at the top of shell, and a part of the top electrode (7) passes through shell and is arranged in surface of shell exposure;Institute It states microprocessor module (4) to be located in the top of shell, be carried by intermediate bulkhead;
Lower electrode (8), the pulse wave acoustic signals acquisition module (3) of the electrocardiogram acquisition module are separately positioned on the lower part of shell; Wherein, a part of the lower electrode (8) passes through shell and exposure is arranged on the surface of shell;The pulse wave acoustic signals acquisition The coupler (9) that the electret microphone front end of module (3) is arranged some pass through shell and the surface of shell exposure set It sets;
Sound insulation chamber (13) are provided with below the shell, are looped around the periphery of exposed coupler (9), lower electrode (8);It is described Shell further includes inner casing (1) and shell (2), and the shell (2) is made of hard material, and the inner casing (1) is sound-proof material.
10. the blood pressure measuring device based on electrocardio and pulse wave acoustic signals as claimed in claim 8, which is characterized in that described micro- After processor module (4) receives electrocardiogram acquisition module, the acquisition data of pulse wave acoustic signals acquisition module (3) are handled, lead to It crosses bluetooth and is sent to host computer signal processing module;
The blood pressure measuring device further includes battery powered power supply module (6), respectively ecg signal acquiring mould Block, pulse wave acoustic signals acquisition module (3) and microprocessor module (4) power supply;
The host computer signal processing module passes through 220V mains-supplied.
CN201910569805.0A 2019-06-27 2019-06-27 Blood pressure measuring device based on electrocardio and pulse wave acoustic signals Pending CN110251108A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
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Application publication date: 20190920