CN110220894A - A kind of household medicine detection paper handkerchief - Google Patents
A kind of household medicine detection paper handkerchief Download PDFInfo
- Publication number
- CN110220894A CN110220894A CN201910566661.3A CN201910566661A CN110220894A CN 110220894 A CN110220894 A CN 110220894A CN 201910566661 A CN201910566661 A CN 201910566661A CN 110220894 A CN110220894 A CN 110220894A
- Authority
- CN
- China
- Prior art keywords
- layer
- paper handkerchief
- sample
- reagent
- household medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
Abstract
The present invention provides a kind of household medicine to detect paper handkerchief, including cleaning layer, saturating sample layer, reagent layer, photic zone and skin-friendly layer, wherein cleaning layer, saturating sample layer, reagent layer and skin-friendly layer are provided with evenly distributed through-hole, the protrusion communicated with cleaning layer is additionally provided on the central through hole of the Dan Yuan of saturating sample layer, the channel of a stored sample can be formed after doubling, the controllable sample size for penetrating into reagent layer obtains accurate detection as a result, also can avoid pollution of the external environment to sample.Household medicine detection paper handkerchief of the invention can detect various samples, and a variety of detection projects carry instant use, breach the limitation of traditional detection test paper application environment.
Description
Technical field
The present invention relates to technical field of biomedical detection more particularly to a kind of household medicine to detect paper handkerchief.
Background technique
Currently, for detecting human body, tear, saliva, urine, excrement etc. with the presence or absence of the content of certain ingredient or the ingredient
Method include dry chemical method and immunofluorescence technique.Correspondingly, in conjunction with the test paper of dry chemical method detection and immuno-fluorescence assay
There are drying chemical reagent paper and immunofluorescence test paper.
Drying chemical reagent paper has the characteristics that easy to use, easy to operate, quick result out.According to detection liquid sample dry
Flow path on chemical test paper, can be by type there are many drying chemical reagent papers, and longitudinally perpendicular Test paper is dry chemistry test
One kind of paper.Longitudinally perpendicular Test paper includes that will be overlapped mutually together with the carrier of reaction reagent, and liquid sample is from upper
Each reaction reagent layer is flowed through under and, finally shows testing result.
But existing drying chemical reagent paper and immunofluorescence test paper generally can be only applied to the particular experiments ring such as hospital, laboratory
Border cannot achieve and use immediately in arbitrary site.The present invention provides a kind of households to detect paper handkerchief, can not be real by environmental restrictions
Existing arbitrary site is easy to use.
Summary of the invention
The purpose of the present invention is to provide a kind of households to detect paper handkerchief, solves the detection of existing test paper by environmental restrictions
Problem, so that detection paper handkerchief of the invention can be realized the instant use in arbitrary site.
In order to achieve the above-mentioned object of the invention, the present invention the following technical schemes are provided:
A kind of household medicine detection paper handkerchief, which is characterized in that including cleaning layer, reagent layer and photic zone, the reagent layer
It is arranged between the cleaning layer and the photic zone, is provided with the folding line for capableing of doubling on the symmetry axis of the detection paper handkerchief.
Further, the detection paper handkerchief further includes sample layer, and the sample layer is arranged in the cleaning layer and the examination
Between oxidant layer, the cleaning layer, saturating sample layer and reagent layer and skin-friendly layer are provided with several through-holes, the through-hole in same position
At least one group is formed by three.
It further, include being provided with one between a centre bore and the centre bore of the cleaning layer in through-hole described in every group
A hollow protrusion, the internal diameter of the protrusion are not less than the internal diameter of the centre bore.
Further, a hollow protrusion is provided on the centre bore of the sample layer, the internal diameter of the protrusion is not small
In the internal diameter of the centre bore of the cleaning layer.
Further, the euphotic other side is additionally provided with skin-friendly layer, and the material of the cleaning layer and skin-friendly layer is equal
For general fibre paper.
Further, the material of the sample layer is in polypropylene, polyethylene, polystyrene, polyester film and poly- starch
One kind.
Further, the euphotic material is in polypropylene, polyethylene, polystyrene, polyester film and poly- starch
One kind.
Further, the material of the reagent layer is biochemical reaction test paper, and the reagent of the reagent layer is dry chemical reaction
Reagent, chromatography reagent, nucleic acid reagent, antibody, small molecule compound detection reagent it is one or more.
Further, the household medicine detection paper handkerchief is made with drawing method.
Beneficial effects of the present invention:
Household medicine detection paper handkerchief of the invention is provided with folding folding line in cleaning layer direction, to be measured in wiping in this way
After object, the duct of the left and right sides can be made to be overlapped by folding napkin, sample to be tested is stored in above-mentioned duct, protection wiping
Layer is readily transported and saves not by outside contamination.
Household medicine provided by the invention detection paper handkerchief is five-layer structure, is respectively provided with acquisition, saturating sample, detection, isolation
Effect.It is not necessarily to strict control sample size when in use, after acquiring sample, will test paper handkerchief doubling, the protrusion being arranged on saturating sample layer
After folding, one can be formed convenient for the channel for the sample size for saving sample and control infiltration reagent layer, reach and quick and precisely examine
The purpose of sample.
Detailed description of the invention
It in order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, below will be to institute in embodiment
Attached drawing to be used is needed to be briefly described, it should be apparent that, the accompanying drawings in the following description is only some implementations of the invention
Example, for those of ordinary skill in the art, without any creative labor, can also be according to these attached drawings
Obtain other attached drawings.
Fig. 1 is the structural schematic diagram in present inventor's medicine detection paper handkerchief.
Fig. 2 is the cross-sectional view of the detection paper handkerchief of present inventor's medicine.
Fig. 3 is one group of through-hole schematic diagram of the detection paper handkerchief of present inventor's medicine.
Wherein, the saturating sample layer of 1- cleaning layer, 2-, 3- reagent layer, 4- photic zone, 5- skin-friendly layer, 6- through-hole, 61- centre bore, 7-
Protrusion, 8- folding line.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
The object of the present invention is to provide a kind of household medicine to detect paper handkerchief, of the existing technology to solve the problems, such as, makes to cure
It learns detection paper handkerchief and realizes the convenient to use of arbitrary site.
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, with reference to the accompanying drawing and specific real
Applying mode, the present invention is described in further detail.
Embodiment one
As shown in Figure 1-3, present embodiments providing a kind of household medicine detection paper handkerchief, cleaning layer 1, photic zone are specifically included
4 and the reagent layer 3 that is arranged between cleaning layer 1 and photic zone 4 be further additionally provided between cleaning layer 1 and reagent layer 3
Saturating sample layer 2, there are also skin-friendly layers 5 for the other side of photic zone 4.Specific cleaning layer 1 and skin-friendly layer 5 are general fibre paper, saturating sample layer 2
For polypropylene material, photic zone 4 is polystyrene material, and reagent layer 3 is biochemical reaction test paper.
As shown in Fig. 2, being provided with several lead in same position in cleaning layer 1, saturating sample layer 2 and reagent layer 3 and skin-friendly layer 5
Hole 6, wherein the through-hole 6 of cleaning layer 1 is the acquisition hole of sample, and sample is quickly streamed by the acquisition hole on cleaning layer 1 to saturating sample
Layer 2.The through-hole 6 of saturating sample layer 2 is the saturating sample hole of sample, will acquire the sample that hole transmits and further transmits to reagent layer 3.Examination
The through-hole 6 of oxidant layer 3 is the detection hole of sample, reacts the sample for reaching detection hole around hole with reagent.Outermost layer
Skin-friendly layer 5 on be provided with peep hole, can by the through-hole 6 observe reagent layer 3 reacting phenomenon, judge testing result.
The through-hole 6 of the present embodiment as shown in figs. 1 and 3 forms one group by 9.Have at the center of every layer of every group of through-hole 6
One centre bore 61 is provided with hollow protrusion 7, the internal diameter of the protrusion 7 and the hole of through-hole 6 on the centre bore 61 of saturating sample layer 2
Diameter ratio is 1.5:1, and is communicated with the centre bore of cleaning layer 1 61.After detecting paper handkerchief doubling, the protrusion 7 of symmetry axis two sides can be formed
One closed duct for sample flow, which, which can be reserved for sample to be tested, makes sample not by environmental pollution, can also be by this
Duct control reaches the sample size of detection hole, avoids excessively directly soaking reagent layer 3 by paper layer due to liquid, liquid is caused to expand
Dissipate it is uncontrollable, to cause testing result inaccurate.
As shown in Figure 1, household medicine detection paper handkerchief has 8 groups of through-holes 6, left and right is respectively distributed with 4 groups and is symmetrical arranged, wherein
The part of symmetry axis is provided with folding line 8, after paper handkerchief wipe samples to be detected, will test paper handkerchief doubling by the folding line 8 being arranged and saves.
After cleaning layer 1 acquires sample, sample to be tested penetrates into sample layer 2 by the through-hole 6 on cleaning layer 1, and by saturating
Sample hole enters reagent layer 3, and sample is reacted on reagent layer 3 with reagent, is blocked by non-porous photic zone 4, and exudation parent is avoided
Skin layers 5 pollute.Sample acquisition after the completion of, through folding line 8 will test paper handkerchief carry out doubling, after doubling left and right two parts paper handkerchief by
In symmetrical structure, through-hole 6 can be overlapped.Hollow protrusion 7, doubling rear left are provided with due to cleaning layer 1 and thoroughly between sample layer 2
The protrusion 7 of right two sides can be closed to form a closed duct, be stored in sample is intact in duct, avoid detection paper handkerchief
Affected by environment, the contaminated samples in storage and transport.The sample of reagent layer 3 is infiltrated by the also controllable sample of the protrusion 7
Amount avoids sample size from excessively directly spreading and sinking in wet reagent layer 3, influences testing result.Sample is after reagent layer 3 is reacted, due to saturating
Photosphere 4 is light transmission material impervious to water, can block fluid sample to photic zone 4 and permeate without continuing to skin-friendly layer 5, to be detected
As a result after showing, user of service can pass through photic zone 4, record testing result by the peep hole on skin-friendly layer 5.In detection paper
During the storage and transport of towel, the general fibre paper of skin-friendly layer 5 will increase detection paper handkerchief and hand or other clamping devices
Frictional force makes to detect the stable transport of paper handkerchief, is not easy to slide.
It is all provided on the cleaning layer 1 of household medicine provided by the invention detection paper handkerchief, saturating sample layer 2, reagent layer 3 and skin-friendly layer 5
Be equipped with through-hole 6, compared with the Test paper of traditional simple layer structure, detection paper handkerchief provided by the invention be multilayered structure and
Through-hole 6 is opened up in certain layer.Traditional detection test paper needs experimenter rationally to control sample to be tested amount, if sample size is excessive, tradition
Test paper oversoaking can inevitably influence testing result.And detection paper handkerchief of the invention passes through the setting of through-hole 6,
Controllable sample flows into reagent layer 3 with First Speed through hole, and excessive sample can be retained in every layer of test paper by horizontal infiltration
Non-porous sections, to regulate and control influence of the sample size to testing result.Also, when sample size is excessive, cleaning layer 1 and saturating sample layer 2
Between protrusion 7 be equivalent to one for liquid flowing channel, by this channel also can control reach reagent layer 3 sample size.
If sample size is very few, the sample on traditional detection test paper is not enough to react with reagent or reacting phenomenon is not significant.But due to
Detection paper handkerchief of the invention has the through-hole 6 of through reagent layer 3, and the speed ratio that sample through hole flow to reagent layer 3 is permeated layer by layer
Speed to reagent layer 3 is fast, even if sample size is very few, sample also can through hole directly contacted with reagent layer 3, and then realize quick
The purpose of detection.
Specific examples are applied in the present invention, and principle and implementation of the present invention are described, above embodiments
Illustrate to be merely used to help understand method and its core concept of the invention；At the same time, for those skilled in the art, according to
According to thought of the invention, there will be changes in the specific implementation manner and application range.In conclusion the content of the present specification
It should not be construed as limiting the invention.
Claims (9)
1. a kind of household medicine detects paper handkerchief, which is characterized in that including cleaning layer, reagent layer and photic zone, the reagent layer is set
It sets between the cleaning layer and the photic zone, is provided with the folding line for capableing of doubling on the symmetry axis of the detection paper handkerchief.
2. a kind of household medicine according to claim 1 detects paper handkerchief, which is characterized in that it further include sample layer, it is described
Sample layer is arranged between the cleaning layer and the reagent layer, and the cleaning layer, saturating sample layer and reagent layer are equal in same position
Several through-holes are provided with, the through-hole at least forms one group by three.
3. a kind of household medicine according to claim 2 detects paper handkerchief, which is characterized in that include one in through-hole described in every group
A centre bore, through-hole described in multiple groups are distributed on detection paper handkerchief in matrix.
4. a kind of household medicine according to claim 3 detects paper handkerchief, which is characterized in that the centre bore of the sample layer with
A hollow protrusion is provided between the centre bore of the cleaning layer, the internal diameter of the protrusion is interior not less than the centre bore
Diameter.
5. a kind of household medicine according to claim 1 or 4 detects paper handkerchief, which is characterized in that described euphotic another
Side is additionally provided with skin-friendly layer, and the material of the cleaning layer and skin-friendly layer is general fibre paper.
6. a kind of household medicine according to claim 2 or 4 detects paper handkerchief, which is characterized in that the material of the sample layer
For one of polypropylene, polyethylene, polystyrene, polyester film and poly- starch.
7. a kind of household medicine according to claim 1 detects paper handkerchief, which is characterized in that the euphotic material is poly-
One of propylene, polyethylene, polystyrene, polyester film and poly- starch.
8. a kind of household medicine according to claim 1 detects paper handkerchief, which is characterized in that the material of the reagent layer is made a living
Change reaction test paper, the reagent of the reagent layer is dry chemical reaction reagent, chromatography reagent, nucleic acid reagent, antibody, small molecule chemical combination
Quality testing test agent it is one or more.
9. a kind of preparation method of household medicine detection paper handkerchief according to claim 1, which is characterized in that the detection paper
Towel is made with drawing method.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910566661.3A CN110220894B (en) | 2019-06-27 | 2019-06-27 | Domestic medical science detects paper handkerchief |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910566661.3A CN110220894B (en) | 2019-06-27 | 2019-06-27 | Domestic medical science detects paper handkerchief |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110220894A true CN110220894A (en) | 2019-09-10 |
| CN110220894B CN110220894B (en) | 2021-10-08 |
Family
ID=67814994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910566661.3A Active CN110220894B (en) | 2019-06-27 | 2019-06-27 | Domestic medical science detects paper handkerchief |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110220894B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113049575A (en) * | 2021-02-23 | 2021-06-29 | 深圳职业技术学院 | Medicine detection device and system |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2725897Y (en) * | 2004-08-20 | 2005-09-14 | 北京金域高科诊断技术有限公司 | Folding trepanning standard colorimetric board |
| CN102128918A (en) * | 2010-11-11 | 2011-07-20 | 艾康生物技术(杭州)有限公司 | Detecting test paper |
| FI123297B (en) * | 2009-05-04 | 2013-02-15 | Valtion Teknillinen | Lateral flow test strip and its manufacturing method |
| CN203898277U (en) * | 2014-06-05 | 2014-10-29 | 四川省医学科学院（四川省人民医院） | Tear detection test paper |
| CN203914738U (en) * | 2014-06-27 | 2014-11-05 | 福建恒利纸业有限公司 | A kind of for clean paper handkerchief |
| CN105651770A (en) * | 2016-01-08 | 2016-06-08 | 昆明泊银科技有限公司 | Double-folding type formaldehyde test paper and formaldehyde detection method |
| CN206281787U (en) * | 2016-12-27 | 2017-06-27 | 天津艾尼克科技发展有限公司 | A kind of sewage detection sulfur compound test paper |
| CN207081663U (en) * | 2017-08-02 | 2018-03-09 | 天津果实科技有限公司 | A kind of miniature urinalysis test paper |
| CN109044166A (en) * | 2018-10-19 | 2018-12-21 | 医芯（厦门）科技有限公司 | Paper handkerchief and preparation method thereof with pH detection function |
-
2019
- 2019-06-27 CN CN201910566661.3A patent/CN110220894B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2725897Y (en) * | 2004-08-20 | 2005-09-14 | 北京金域高科诊断技术有限公司 | Folding trepanning standard colorimetric board |
| FI123297B (en) * | 2009-05-04 | 2013-02-15 | Valtion Teknillinen | Lateral flow test strip and its manufacturing method |
| CN102128918A (en) * | 2010-11-11 | 2011-07-20 | 艾康生物技术(杭州)有限公司 | Detecting test paper |
| CN203898277U (en) * | 2014-06-05 | 2014-10-29 | 四川省医学科学院（四川省人民医院） | Tear detection test paper |
| CN203914738U (en) * | 2014-06-27 | 2014-11-05 | 福建恒利纸业有限公司 | A kind of for clean paper handkerchief |
| CN105651770A (en) * | 2016-01-08 | 2016-06-08 | 昆明泊银科技有限公司 | Double-folding type formaldehyde test paper and formaldehyde detection method |
| CN206281787U (en) * | 2016-12-27 | 2017-06-27 | 天津艾尼克科技发展有限公司 | A kind of sewage detection sulfur compound test paper |
| CN207081663U (en) * | 2017-08-02 | 2018-03-09 | 天津果实科技有限公司 | A kind of miniature urinalysis test paper |
| CN109044166A (en) * | 2018-10-19 | 2018-12-21 | 医芯（厦门）科技有限公司 | Paper handkerchief and preparation method thereof with pH detection function |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113049575A (en) * | 2021-02-23 | 2021-06-29 | 深圳职业技术学院 | Medicine detection device and system |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110220894B (en) | 2021-10-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Weng et al. | Recent advances in thread-based microfluidics for diagnostic applications | |
| US8206992B2 (en) | Cotton thread as a low-cost multi-assay diagnostic platform | |
| KR101960585B1 (en) | Attaching type chemical snesor comprising hydrogel and method for preparing the same | |
| SK99297A3 (en) | Volume independent diagnostic test element and method to assay analytes using it | |
| JPH0746107B2 (en) | Test method | |
| MXPA97005535A (en) | Carrier of diagnostic test independent of the volume and methods in which they are used to determine an analyst or substance that goes to anali | |
| CZ227597A3 (en) | Diagnostic carrier with multilayer test field and method of determining analyte by making use thereof | |
| JP5198399B2 (en) | Surface treatment apparatus for biological sample holding sheet, surface treatment method for biological sample holding sheet, biological sample processing apparatus, and biological sample processing method | |
| JPH04507146A (en) | Analytical test equipment for specific binding assays | |
| JPH1078432A (en) | Carrier for diagnostic test and method for measurement of object to be analyzed by using it | |
| CN101852799A (en) | Immunochromatography assay detection reagent and preparation method thereof | |
| CN110220894A (en) | A kind of household medicine detection paper handkerchief | |
| CN102482071A (en) | Three-dimensional microfluidic systems | |
| JPH03130662A (en) | Device and method for separating plasma from blood and method of measuring analytic object in blood | |
| JP4402263B2 (en) | Chromatographic quantitative measurement device | |
| JP2016125875A (en) | Sample pad and liquid sample inspection tool using the same | |
| AU2014221626A1 (en) | Fluidic device and fabrication method thereof, and thermal transfer medium for fluidic device fabrication | |
| US10473656B2 (en) | Testing device including resin layer, testing kit, transfer member, testing device fabrication method, and testing method | |
| CN207133195U (en) | Multichannel collaurum/Immunofluorescence test micro-fluidic chip | |
| CN106970218A (en) | A kind of vaginitis self-test device | |
| KR100485564B1 (en) | Chromatography measuring instrument | |
| CN109073643A (en) | The forming method and immunochromatography check device in the sample addition portion of immunochromatography check device | |
| CN101846678A (en) | Rapid immunochromatographic reagent strip test method suitable for multiple samples | |
| WO2008086845A1 (en) | Lateral-flow test device providing improved test quality | |
| CN208922633U (en) | A kind of imbibition indicate indicator and liquid-detecting |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |