CN110201288A - A kind of seal wire and its preparation method and application for blood vessel intervention - Google Patents
A kind of seal wire and its preparation method and application for blood vessel intervention Download PDFInfo
- Publication number
- CN110201288A CN110201288A CN201910510595.8A CN201910510595A CN110201288A CN 110201288 A CN110201288 A CN 110201288A CN 201910510595 A CN201910510595 A CN 201910510595A CN 110201288 A CN110201288 A CN 110201288A
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- CN
- China
- Prior art keywords
- blood vessel
- seal wire
- vessel intervention
- section
- coil structures
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M2025/0177—Introducing, guiding, advancing, emplacing or holding catheters having external means for receiving guide wires, wires or stiffening members, e.g. loops, clamps or lateral tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09108—Methods for making a guide wire
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09175—Guide wires having specific characteristics at the distal tip
Abstract
The invention discloses a kind of seal wires and its preparation method and application for blood vessel intervention, wherein, the seal wire for blood vessel intervention, including guidewire body, the guidewire body is many coil structures in distal site spiral winding, and many coil structures are extended into wire distal by guidewire proximal and extend spirally section.The inside for extending spirally section, which has, connects channel, and the equal ring cloth of each circle in many coil structures is connecting channel periphery.The channel that connects is along linear extension, and extending direction is consistent with the length direction of seal wire.Provided by the present invention for the seal wire and its preparation method and application of blood vessel intervention, structure is simple, easy to operate, can guarantee passing through for surgical instrument in Complex Coronary intervention operation significantly, shorten operating time, improve success rate of operation.
Description
Technical field
The present invention relates to the field of medical instrument technology, and in particular to a kind of seal wire and preparation method thereof for blood vessel intervention
And application.
Background technique
The main reason for atherosclerosis is coronary heart disease, cerebral infarction and peripheral vascular disease, it is serious to influence people's
Health and quality of life.Interventional therapy is to be effectively improved the clinical solution of patients with coronary heart disease life quality, at present I
State's percutaneous coronary intervention has reached 800,000 every year, and with the growth of amount for surgical, Complex Coronary interventional therapy is also corresponding
Increase, special in face of part anatomical structure, when the especially complex blood vessel of lesion, surgical instrument, which can not be successfully, to be passed through, and causes to perform the operation
Time extends, and dose radiation and contrast medium dosage increase, and influences the completion for the treatment of.
In the prior art, in order to better by surgical instrument, need using two or more root PTCA seal wire carries out
Support is perhaps anchored using PTCA sacculus or carries out transition using elongate catheter.All there is success rate not in these schemes
Height, operating time extend, and instrument expense increases the problems such as excessive.
Summary of the invention
The present invention provides a kind of seal wires and its preparation method and application for blood vessel intervention, and structure is simple, operation side
Just, it can guarantee that surgical instrument passes through in Complex Coronary intervention operation, shortens operating time, improves successful surgery significantly
Rate.
A kind of seal wire for blood vessel intervention, including guidewire body, the guidewire body be in distal site spiral winding
Many coil structures, many coil structures are extended into wire distal by guidewire proximal and extend spirally section.
The guidewire body rotate while extending along the axis from coil to coil arranging around a certain axis, forms spiral winding
Many coil structures, the axis is to extend spirally the axis of section, extend spirally section axis and extended state under guidewire body
Axis it is parallel, or be located along the same line.
Guidewire body extends 360 degree around the axis for extending spirally section, and path experienced is a circle.In many coil structures
It is parallel to each other between each circle, on the axis direction for extending spirally section, equidistantly arrangement or non-equidistant arrangement between each circle.Spiral is prolonged
When stretching intersegmental part and being equipped with other seal wires, when promotion extends spirally section along the sliding of its internal seal wire, extend spirally each in section
The deformation of adaptability can occur for circle, change the inner diameter size of each circle to meet the needs of sliding.
The hand of spiral for extending spirally section is unlimited, i.e., from the distal end of seal wire to the proximal end of seal wire, guidewire body both may be used
To extend spirally section described in rotation counterclockwise formation, it can also rotate clockwise and extend spirally section described in being formed.
Of the invention theing improvement is that extends spirally section, and the structure at other positions of seal wire, material and preparation method are equal
The prior art can be used.
Preferably, the inside for extending spirally section, which has, connects channel, the equal ring cloth of each circle in many coil structures exists
Connect channel periphery.
Extend spirally section each coil structures surround jointly it is described connect channel, the channel that connects is for passing through through seal wire
The seal wire worn can be conventional guidewire in the prior art, or seal wire provided by the invention.
Preferably, the channel that connects is along linear extension, and extending direction is consistent with the length direction of seal wire.
By thermal finalization obtain it is described connect channel state extending in a straight line, after sizing finishes, in force external force
Under effect, the shape for connecting channel may change.
Preferably, section outer diameter that extends spirally is 0.1~0.2cm.The internal diameter for connecting channel be 0.03~
0.08cm。
The internal diameter for connecting channel depends on the outer diameter of internal perforative seal wire, in order to which guarantee can between two seal wires
Enough opposite slidings realized under external force, and can be realized and the position of mutually locking is kept to close in the case where not applying external force
System, the internal diameter for connecting channel are equal or slightly larger than the diameter of internal perforative seal wire.
Both the locking of positional relationship is not necessarily referring to the absolute constant of the two relative positional relationship between two seal wires, and refer to
The more difficult change of relative positional relationship, or change smaller.
The internal diameter for connecting channel refers under the premise of inside does not wear other seal wires, in the raw interior
Diameter, when connect other seal wires are equipped with by inside when, extend spirally section it is each circle between generate adaptability deformation, each corral at
The internal diameter for connecting channel increase, to meet the current demand of seal wire.
The outer diameter for extending spirally section is codetermined by the string diameter of the internal diameter and guidewire body that connect channel.
Preferably, section outer diameter that extends spirally is 0.12~0.15cm.The internal diameter for connecting channel be 0.04~
0.06cm.Most preferably, the internal diameter for connecting channel is 0.048cm.
Preferably, described extend spirally in section, the string diameter of guidewire body is 0.03~0.04cm.
Described to extend spirally in section, the outer diameter of guidewire body can be isometrical extension or non-isometrical extension, isometrical prolong non-
When stretching, guidewire body is gradually reduced by proximal end to distal direction.
The string diameter of guidewire body distal end is smaller, can suitably reduce intensity, reduces the damage to the blood vessel being in contact
Wound.
Preferably, described extend spirally in section, guidewire body includes metal core filaments and is wrapped in outside metal core filaments
Casing.
The guidewire body extended spirally in section can use Nitinol material with the prior art, the metal core filaments,
Described sleeve pipe uses polyurethane material.
The prior art can be used in the material and structure at other positions in seal wire other than extending spirally section.
The outer wall of the metal core filaments is coated with hydrophilic coating, and the outer wall of described sleeve pipe is coated with hydrophilic coating.
Preferably, each circle outer diameter for extending spirally section is identical, or it is gradually reduced by guidewire proximal to wire distal.
Namely extend spirally section integrally isometrical extension or non-isometrical extension.Preferably, extend spirally section entire outer diameter by
Guidewire proximal to wire distal is gradually reduced.Namely be substantially conical, tapered end is located at the end for extending spirally section.
Preferably, the section that extends spirally has the slidably state being arranged over the guide.
The guide part can be conventional guidewire or seal wire provided by the invention.As a kind of usage mode, the spiral
Extended segment is arranged over the guide, and under external force, extending spirally section can counter-guide sliding.
In use, guide part (such as another conventional guidewire) can first be intervened, then by the spiral winding of seal wire of the present invention
Structure cover over the guide, and to distal end push, during push spiral winding structure can adaptive directed part outer diameter, push
After in place, spiral winding structure is prevented axially opposing sliding, is passed through with the phase position for tightening force locking and guide part of itself
The mode of two or more seal wires enhances supportive on the whole.
Preferably, adjacent each circle successively reclines in many coil structures.Successively patch can guarantee the beam to guide part to adjacent each circle
Clamp force improves locating effect.
Preferably, described connect channel and the guide part tight fit.
The tight fit refers to: under the action of no external force, the guide part does not generate phase with connecting between channel
To sliding.
It can establish stable locking relation between section and guide part to guarantee to extend spirally, there is enough frictions
Power, it is preferable that the circle number of many coil structures is greater than 10 circles.Further preferably, the circle number of many coil structures is 10~20 circles,
Further preferably, 10~15 circle.
The channel that connects needs to have enough length, has foot between the guide part to guarantee and connect channel interior
Enough contacts area guarantee there is suitable frictional force between guide part and the inner wall for connecting channel, it is preferable that it is described connect it is logical
The length in road is 0.5~1.5cm.Further preferably, the length for connecting channel is 0.7~1.0cm.
As another usage mode, the section that extends spirally is unfolded to protrude into conduit to walk state with each circle, with
And it is pierced by the anchoring states that deploying portion after conduit is restored to many coil structures.
Each circle expansion linear state (and the non-critical straight line, but at least can be by leading for extending spirally section
Pipe), it then protrudes into conduit and walks, after being pierced by conduit, extend spirally section under the function that own material is remembered, be restored to multi-turn
The anchoring states of structure.
The anchoring states are completed by the mutual extrusion between many coil structures and vascular wall, i.e. the spiral of many coil structures is prolonged
It stretches section support in the blood vessels, plays the role of anchoring.
Section support is extended spirally in the blood vessels, in order to avoid causing to damage to blood vessel, it is preferable that the circle number of many coil structures
For 2~8 circles.Further preferably, the circle number of many coil structures is 3~5 circles.
The present invention also provides a kind of more godet systems for blood vessel intervention, including guide part and described it to be used for blood
The seal wire of pipe intervention, the section that extends spirally have the slidably state being arranged over the guide.
The present invention also provides it is a kind of for blood vessel intervention can positioning guide wire system, including conduit and described be used for
There is the section that extends spirally of the seal wire of blood vessel intervention, seal wire each circle expansion to protrude into the state of walking in conduit, and be pierced by described
Deploying portion is restored to the anchoring states of many coil structures after conduit.
The present invention also provides the preparation methods of the seal wire for blood vessel intervention described in one kind, comprising: by metal core filaments
Corresponding site on core bar spiral winding be many coil structures, after thermally treated sizing, then metal core filaments stretching be mounted on it is poly-
In urethane casing, guidewire body reverts to spiral winding structure after cancelling drawing force.
The metal core filaments can have the material of memory function using Nitinol etc., and metal core filaments are corresponded to spiral and are prolonged
The part helix for stretching section position is wrapped on core bar, and the spacing of two adjacent rings is set as needed, passes through heat treatment shaping
Afterwards, spiral winding structure can be obtained extends spirally section.
After heat treatment, metal core filaments are straightened to the assembly for carrying out polyurethane casing, restore spiral knot in metal core filaments
When structure, polyurethane casing is driven to crimp therewith, forms spiral winding structure.
Provided by the present invention for the seal wire and its preparation method and application of blood vessel intervention, structure is simple, easy to operate, increases
The supportive of strong godet system, the delivery instrument that hits pay dirk reach the purpose that lesion is treated.
Detailed description of the invention
Fig. 1 is schematic diagram of the present invention for the seal wire of blood vessel intervention；
Fig. 2 is the portion the A enlarged drawing in Fig. 1；
Fig. 3 is another structural schematic diagram that section is extended spirally in seal wire of the present invention for blood vessel intervention；
Fig. 4 a is the schematic diagram of guide part；
Fig. 4 b is the schematic diagram that a seal wire is combined on guide part；
Fig. 4 c is the schematic diagram that two seal wires are combined on guide part；
Fig. 4 d is the schematic diagram that three seal wires are combined on guide part；
Fig. 4 e is the schematic diagram that foley's tube is advanced along guide part；
Fig. 4 f is the schematic diagram that foley's tube is advanced along seal wire；
Fig. 5 a stretches for seal wire to be unfolded to connect schematic diagram in the catheter；
Fig. 5 b is that the section that extends spirally of seal wire is pierced by the schematic diagram for being restored to many coil structures from conduit；
Fig. 5 c is the schematic diagram that foley's tube is advanced along seal wire；
Fig. 5 d is the schematic diagram that foley's tube marches to wire distal along seal wire.
In figure: 1, seal wire；2, section is extended spirally；3, conduit；4, foley's tube；5, guide part.
Specific embodiment
With reference to the accompanying drawing, the present invention is described in detail for the seal wire and its preparation method and application of blood vessel intervention.
Embodiment 1
As shown in Figure 1 and Figure 2, a kind of seal wire for blood vessel intervention, including guidewire body, guidewire body is in distal site
Spiral winding is many coil structures, and many coil structures are arranged into guidewire proximal extension by wire distal and extend spirally section 2.
It is proximally and distally relative concept in the present invention, wherein proximal end refers to close to one end of operator, distally refers to separate
One end of operator.B is distal end in Fig. 1, and C is proximal end.
In the present embodiment, in the case where guidewire body stretches expansion, the length of guidewire body is 145cm, guidewire body
Proximal part material be 316L stainless steel, be coated with PTFE coating, proximal end portion diameter 0.036cm outside proximal part.
In the case where guidewire body stretches expansion, the distal portions material of guidewire body is Nitinol, distal portions
Length be 40cm, be coated with hydrophilic coating outside distal portions, tungstenic polyurethane casing, the poly- ammonia of tungstenic be arranged on distal portions
The length of ester casing is 25cm, and jacket exterior is coated with hydrophilic coating.
End diameter that distal portions are connected with close end split-phase (including tungsten polyurethane casing) is 0.036cm, along from close
The direction to distal end is held, the diameter of distal portions gradually becomes smaller.
It extends spirally section 2 and determines that axis continuously forms around the home around one by the distal end of guidewire body, extend spirally each circle of section 2
Outer diameter may be the same or different.As shown in Fig. 2, each circle outer diameter for extending spirally section 2 is identical, as shown in figure 3, spiral is prolonged
Each circle outer diameter for stretching section 2 is gradually reduced by guidewire proximal to wire distal.
As shown in Fig. 2, each circle outer diameter for extending spirally section 2 is 0.12cm, internal diameter 0.048cm, length (i.e. L in Fig. 2
Size) it is 0.8cm.
As shown in Figure 2 and Figure 3, the inside for extending spirally section 2, which has, connects channel, the equal ring cloth of each circle in many coil structures
Connecting channel periphery.Channel is connected along linear extension, and extending direction is consistent with the length direction of seal wire 1.
The circle number for extending spirally section 2 can be set as needed, on the basis of extending spirally the certain point in section 2, around leading
For the axis direction of silk 1 around 360 degree, the path passed by is a circle.According to the different use occasions of seal wire 1, can be set
Different circle numbers are to meet needs.
Embodiment 2
As shown in Figure 4 b, a kind of more godet systems for blood vessel intervention, including guide part 5 and such as institute in embodiment 1
The seal wire 1 for blood vessel intervention stated.
As shown in fig. 4 a, guide part 5 can use seal wire in the prior art, only illustrate seal wire in the prior art in Fig. 4 a
Shape, detail omit expression.
As shown in Figure 4 b, extending spirally section 2 has the slidably state being set on guide part 5, and guide part 5 is located at spiral
Extended segment 2 connects in channel, and extends spirally between section 2 and guide part 5 as tight fit.
In the present embodiment, the circle number for extending spirally section 2 is greater than 10 circles.
Guide part 5 is one, can cooperate more seal wires 1 described in embodiment 1 simultaneously on guide part 5, as illustrated in fig. 4 c,
Two seal wires 1 are combined with simultaneously on guide part 5, as shown in figure 4d, are combined with three seal wires 1 on guide part 5 simultaneously.
Extending spirally for each seal wire 1 forms close-fitting relationship between section 2 and guide part 5, by extending spirally section 2 and leading
Matching relationship between part 5 prevents from extending spirally the opposite sliding of generation between section 2 and guide part 5.
Such as Fig. 4 e, as shown in fig. 4f, each seal wire 1 and guide part 5 can be used as path, guidance interventional medical device into
Enter in vivo.
Specific example is such as: in PTCA operation, when PTCA seal wire has arrived at blood vessel commitment positions, and other intervention medical treatment
Instrument can use more godet systems provided in this embodiment, i.e., since the complexity of disease can not be successfully through diseased region
By the tail portion for extending spirally section 2 and being set in PTCA seal wire (i.e. guide part 5) for the seal wire 1 for providing embodiment 1, and in outer masterpiece
Under, the distal end of blood vessel is reached along PTCA seal wire.
Outer wall due to extending spirally metal core filaments and casing in section 2 is coated with hydrophilic coating, can very smoothly
It by complex lesions position, extends spirally and forms stable position locking between section 2 and guide part 5, prevent the two mutually sliding,
Other interventional medical devices are entered and form good support in vivo.
Embodiment 3
It is a kind of for blood vessel intervention can positioning guide wire system, including described in conduit 3 and embodiment 1 be used for blood vessel
There is the section 2 that extends spirally of the seal wire 1 of intervention, seal wire 1 each circle expansion to protrude into the state of walking in conduit 3, and be pierced by conduit 3
Deploying portion is restored to the anchoring states of many coil structures afterwards.
In the present embodiment, the circle number for extending spirally section 2 is 2~8 circles.
The implementation process of the present embodiment is specific as follows as shown in Fig. 5 a~Fig. 5 b:
As shown in Figure 5 a, each circle expansion for extending spirally section 2 of seal wire 1 linearly, and along 3 axis direction of conduit to conduit
3 distal ends are walked；
As shown in Figure 5 b, seal wire 1 extends spirally after section 2 is pierced by 3 distal end of conduit, and the deploying portion for extending spirally section 2 is multiple
Originally it was the anchoring states of many coil structures, and withdrew from conduit 3, and extended spirally section 2 and reply spiral winding state, and the shape between vascular wall
At extruding, play the role of anchoring；
As shown in Fig. 5 c, Fig. 5 d, the medical instrument (such as foley's tube 4) with guide channel is moved along seal wire 1, until
Reach target position.
Embodiment 4
A kind of preparation method for the seal wire of blood vessel intervention as described in Example 1, comprising: by the corresponding of metal core filaments
Position spiral winding on core bar is many coil structures, after thermally treated sizing, then metal core filaments is stretched and are mounted on polyurethane sleeve
In pipe, guidewire body reverts to spiral winding structure after cancelling drawing force.
Metal core filaments use Nitinol material, are covered with hydrophilic coating in metal core filaments.Also parent is covered with outside polyurethane casing
Water coating.The material of hydrophilic coating selects and coating processes use the prior art.
According to the disclosure and teachings of the above specification, those skilled in the art in the invention can also be to above-mentioned embodiment party
Formula carries out change and modification appropriate.Therefore, the invention is not limited to the specific embodiments disclosed and described above, to this
Some modifications and changes of invention should also be as falling into the scope of the claims of the present invention.In addition, although this specification
In use some specific terms, these terms are merely for convenience of description, does not limit the present invention in any way.
Claims (19)
1. a kind of seal wire for blood vessel intervention, including guidewire body, which is characterized in that the guidewire body is in distal site spiral shell
Rotation is wound up as many coil structures, and many coil structures are extended into wire distal by guidewire proximal and extend spirally section.
2. the seal wire for blood vessel intervention as described in claim 1, which is characterized in that the inside for extending spirally section has
Channel is connected, the equal ring cloth of each circle in many coil structures is connecting channel periphery.
3. the seal wire for blood vessel intervention as claimed in claim 2, which is characterized in that the channel that connects along linear extension,
And extending direction is consistent with the length direction of seal wire；On the extending direction for connecting channel, many coil structures from coil to coil arrangement.
4. the seal wire for blood vessel intervention as described in claim 1, which is characterized in that section outer diameter that extends spirally is 0.1
~0.2cm.
5. the seal wire for blood vessel intervention as claimed in claim 2, which is characterized in that the internal diameter for connecting channel is 0.03
~0.08cm.
6. the seal wire for blood vessel intervention as described in claim 1, which is characterized in that described to extend spirally in section, seal wire sheet
The string diameter of body is 0.03~0.04cm.
7. the seal wire as described in any one of claims 1 to 6 for blood vessel intervention, which is characterized in that described to extend spirally section
In, guidewire body includes metal core filaments and the casing that is wrapped in outside metal core filaments.
8. the seal wire for blood vessel intervention as claimed in claim 7, which is characterized in that the metal core filaments use Nitinol
Material, described sleeve pipe use polyurethane material.
9. the seal wire for blood vessel intervention as claimed in claim 7, which is characterized in that the outer wall of described sleeve pipe is coated with hydrophilic painting
Layer.
10. the seal wire for blood vessel intervention as described in claim 1, which is characterized in that each circle for extending spirally section is outer
Diameter is identical, or is gradually reduced by guidewire proximal to wire distal.
11. as described in claim 1 for blood vessel intervention seal wire, which is characterized in that it is described extend spirally section have be arranged
Slidably state over the guide.
12. the seal wire for blood vessel intervention as claimed in claim 11, which is characterized in that described to connect channel and the guiding
Part tight fit.
13. the seal wire for blood vessel intervention as claimed in claim 11, which is characterized in that the circle number of many coil structures is greater than
10 circles.
14. the seal wire for blood vessel intervention as claimed in claim 11, which is characterized in that the length for connecting channel is
0.5~1.5cm.
15. the seal wire for blood vessel intervention as described in claim 1, which is characterized in that the section that extends spirally is with each circle
State of walking in conduit is protruded into expansion, and is pierced by the anchoring states that deploying portion after conduit is restored to many coil structures.
16. the seal wire for blood vessel intervention as claimed in claim 15, which is characterized in that the circle number of many coil structures is 2
~8 circles.
17. it is a kind of for blood vessel intervention more godet systems, including guide part and as claim 1~14 it is described in any item
For the seal wire of blood vessel intervention, extending spirally section has the slidably state being arranged over the guide.
18. it is a kind of for blood vessel intervention can positioning guide wire system, including conduit and such as claim 1~10, in 15~16
The section that extends spirally of described in any item seal wires for blood vessel intervention, seal wire is unfolded to protrude into conduit to walk shape with each circle
State, and it is pierced by the anchoring states that deploying portion after the conduit is restored to many coil structures.
19. a kind of preparation method of the described in any item seal wires for blood vessel intervention of such as claim 1~16, feature exist
In, comprising: by the corresponding site of metal core filaments, spiral winding is many coil structures on core bar, after thermally treated sizing, then gold
Belong to core filaments stretching to be mounted in polyurethane casing, guidewire body reverts to spiral winding structure after cancelling drawing force.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810750210 | 2018-07-10 | ||
| CN2018107502100 | 2018-07-10 |
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| CN110201288A true CN110201288A (en) | 2019-09-06 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201910510595.8A Pending CN110201288A (en) | 2018-07-10 | 2019-06-13 | A kind of seal wire and its preparation method and application for blood vessel intervention |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113017779A (en) * | 2019-12-09 | 2021-06-25 | 上海微创医疗器械（集团）有限公司 | Locking device and rotary grinding medical instrument |
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| CN107865996A (en) * | 2017-07-17 | 2018-04-03 | 杭州启明医疗器械有限公司 | A kind of seal wire |
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| CN113017779A (en) * | 2019-12-09 | 2021-06-25 | 上海微创医疗器械（集团）有限公司 | Locking device and rotary grinding medical instrument |
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Application publication date: 20190906 |