CN110200696A - Vacuum heat-insulation device, its manufacturing method and cryoablation needle - Google Patents
Vacuum heat-insulation device, its manufacturing method and cryoablation needle Download PDFInfo
- Publication number
- CN110200696A CN110200696A CN201910510179.8A CN201910510179A CN110200696A CN 110200696 A CN110200696 A CN 110200696A CN 201910510179 A CN201910510179 A CN 201910510179A CN 110200696 A CN110200696 A CN 110200696A
- Authority
- CN
- China
- Prior art keywords
- thermal insulator
- vacuum
- stainless steel
- insulation device
- vacuum heat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0293—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument interstitially inserted into the body, e.g. needle
Abstract
The invention discloses a kind of vacuum heat-insulation device, its manufacturing method and cryoablation needles, belong to technical field of medical equipment.The vacuum heat-insulation device includes thermal insulator outer tube and thermal insulator inner tube；In thermal insulator inner tube, thermal insulator outer tube and the both ends vacuum welding of thermal insulator inner tube seal thermal insulator outer pipe sleeve, make to form vacuum cavity between thermal insulator outer tube and thermal insulator inner tube；High-temperature resistant fiber layer is provided in thermal insulator internal layer pipe outer wall；Powdery getter is equably provided on high-temperature resistant fiber layer；High-temperature resistant fiber layer and powdery getter are respectively positioned in vacuum cavity.The present invention also provides the manufacturing methods of above-mentioned vacuum heat-insulation device and the cryoablation needle being made from it.The present invention solves the problems, such as the shank frostbite of cryoablation needle using vacuum heat-insulation technology, solving shank natural torsion simultaneously leads to heat-insulated ectonexine contact conduction cooling capacity, and the problem of improve vacuum degree and prevent vacuum heat-insulation device from causing vacuum degree to decline as time goes by.
Description
Technical field
The present invention relates to technical field of medical equipment, in particular to a kind of vacuum heat-insulation device, its manufacturing method and freezing disappear
Melt needle.
Background technique
Argon helium knife cryosurgery system is a kind of Medical Devices of minimally invasive superfreeze ablated tumor, by host, freezing
Probe (freezer unit), high-pressure air source and corresponding accessory structure composition, have both superfreeze, insertion thermotherapy, Immune-enhancing effect etc.
Multiple therapeutic effects.It emphasize it is minimally invasive, target and wipe out tumour, can be accurately positioned and accurately destroy cancerous tissue and maximum
Limit protects normal tissue, provides effective treatment method to kill tumour rapidly and eliminating tumor load.Wherein, cryoprobe is
A piece hollow stainless pin, probe interior are recycled high normal pressure and temperature argon gas (for freezing) or high normal pressure and temperature helium (for making
Heat).High pressure argon gas rapid expansion inside point of a knife can get refrigeration (Joule-Thomson effect), freeze lesion in tens seconds
Tissue is to -100 DEG C or less.High-pressure helium rapid expansion inside point of a knife can heat, and quickly heating is in the lesion of icing condition
Tissue, makes its cell rupture, achievees the purpose that rapid inactivation.
Currently, having the equipment in Israel and the U.S. in the world is the cryosurgery system of the comparative maturity of representative, such as with
The product of Se Lie Galilmedical company, the operating process that cryoablation operation is carried out using the product includes: 1) in image
Under the guidance for learning equipment (CT or color ultrasound), cryoprobe percutaneous puncture to tumor locus usually passes through cryoprobe swollen
Tumor and needle point is just pierced by；2) start cold therapy, throttled usually inside cryoprobe by argon gas and generate low temperature (joule soup
The inferior principle of nurse).But this cryosurgery system there is a problem of one it is more serious: 1) purpose treated merely desires to inactivation target disease
Stove, as far as possible reservation normal tissue；This cryosurgery system is due to being at ultralow temperature when whole cryoprobe works
State, inevitably by the tissue frostbite around shank, especially parts of skin；It is needed when company, Israel early production is performed the operation
It ceaselessly to instil physiological saline in skin surface shank position, to prevent skin frostbite, even if similarly there is many skins in this way
The patient of skin frostbite.2) due to throttling refrigeration power limited, many cooling capacity are wasted in shank part, lead to needle point tumour position
The freezing power set reduces, and direct result is exactly that needle point freezing range is smaller, and it is incomplete in turn result in inactivation.3) biggish swollen
In tumor treatment, doctor can only increase cryoprobe to realize preferable therapeutic effect, with spininess joint freezing to reach larger
Freezing range, increase medical expense in this way.In order to solve the problems, such as shank frostbite skin, company, Israel is in cryoprobe
Inside increases electric heater unit, and electrified regulation shank makes it not less than zero degree, so as to avoid shank surrounding tissue frostbite.
But refrigeration work consumption is reduced since electric heating counteracts a part of cooling capacity, cause the minimum temperature of its cryoprobe to rise, example
It is such as found through overtesting, can reach -120 DEG C without electrically heated cryoprobe, there is electrically heated cryoprobe there was only -70 DEG C,
Such direct result is freezing range shorter, and inactivation is incomplete.
Summary of the invention
In order to solve cryoablation operation in shank frostbite skin, needle point freezing efficiency is low the problems such as, the present invention provides
A kind of vacuum heat-insulation device, including thermal insulator outer tube and thermal insulator inner tube；The thermal insulator outer pipe sleeve is in the thermal insulator
In inner tube, the thermal insulator outer tube and the both ends vacuum welding of thermal insulator inner tube are sealed, make the thermal insulator outer tube with
Vacuum cavity is formed between thermal insulator inner tube；High-temperature resistant fiber layer is provided in the thermal insulator internal layer pipe outer wall；It is described resistance to
Powdery getter is equably provided on high temperature fiber layer；The high-temperature resistant fiber layer and powdery getter are respectively positioned on the vacuum
In cavity.
The difference of the thermal insulator outer layer pipe outside diameter and the thermal insulator internal layer pipe outside diameter is less than or equal to 0.6mm.
The thermal insulator outer layer length of tube is 1mm-6mm smaller than the thermal insulator internal layer length of tube.
The thermal insulator outer tube and thermal insulator inner tube are stainless steel capillary.
The present invention provides a kind of above-mentioned vacuum heat-insulation device manufacturing methods, comprising:
First stainless steel capillary is placed in vacuum brazing furnace, and the heating anneal under condition of high vacuum degree；
By after annealing the first stainless steel capillary and the second stainless steel capillary carry out electronickelling processing；
The outer wall of electronickelling treated the second stainless steel capillary is wound into high-temperature fibre, and fine in the high temperature resistant
Getter is equably sprinkled in dimension；
By the first Stainless Steel Capillary pipe sleeve on second stainless steel capillary；
First stainless steel capillary both ends are subjected to necking processing, and use soldering flux by the described first stainless steel wool
Tubule and the second stainless steel capillary both ends vacuum welding seal.
The temperature of the annealing is 600-900 DEG C；The high-temperature fibre includes the asbestos fibre or pottery of low thermal conductivity
Porcelain fiber；The getter is nonevaporable getter, including zirconium vanadium iron nonevaporable getter.
First stainless steel capillary both ends carry out necking treated internal diameter and second stainless steel capillary
Outer diameter is equal.
It is described using soldering flux that first stainless steel capillary and the second stainless steel capillary both ends vacuum welding is close
The step of envelope includes:
3/4ths circles are smeared in first stainless steel capillary and the second stainless steel capillary both ends commissure to be brazed
Agent；
By smear soldering flux after the first stainless steel capillary and the second stainless steel capillary lie on graphite pallet, and
A quarter circle is set not smear being directed downward for soldering flux；
The graphite pallet is put into vacuum brazing furnace, and is warming up to 860 DEG C under vacuum conditions；
When the vacuum brazing in-furnace temperature is lower than 50 DEG C, the graphite pallet is taken out.
The shape of the soldering flux includes sheet, filiform, powdery and paste.
The soldering flux is auri soldering flux；The shape of the auri soldering flux is paste.
The vacuum degree of the vacuum condition is less than or equal to 10-4Pa。
Described the step of being warming up to 860 DEG C, specifically includes: 500 DEG C are warming up to 300 DEG C/h of heating rate first,
Heat preservation 30 minutes；Then 800 DEG C are warming up to 150 DEG C/h of heating rate, keep the temperature 30 minutes；Finally with 150 DEG C/h
Heating rate be warming up to 860 DEG C, keep the temperature 10 minutes.
The present invention also provides the cryoablation needle being made of above-mentioned vacuum heat-insulation device, including it is probe bodies, appendix, true
Empty thermal insulator and heat exchanger；The vacuum heat-insulation device is arranged in the probe bodies front end；The heat exchanger is arranged in institute
State probe bodies rear end；The appendix passes through the heat exchanger and vacuum heat-insulation device；The output end of the appendix is arranged
There is throttle orifice；The vacuum heat-insulation device includes thermal insulator outer tube and thermal insulator inner tube；The thermal insulator outer pipe sleeve is in institute
It states in thermal insulator inner tube, the thermal insulator outer tube and the both ends vacuum welding of thermal insulator inner tube seal, and make the thermal insulator
Vacuum cavity is formed between outer tube and thermal insulator inner tube；High-temperature fibre is provided in the thermal insulator internal layer pipe outer wall
Layer；Powdery getter is equably provided on the high-temperature resistant fiber layer；The high-temperature resistant fiber layer and the equal position of powdery getter
In in the vacuum cavity.
The present invention solves the problems, such as the shank frostbite of cryoablation needle using vacuum heat-insulation technology, provided by the invention true
Empty thermal insulator has many advantages, such as that compact, vacuum heat-insulation effect are good, can be widely applied to the heat-insulated of various miniature device/equipment
Processing.Cryoablation needle provided by the invention improves safety, the validity of cryoablation.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of vacuum heat-insulation device provided in an embodiment of the present invention；
Fig. 2 is vacuum heat-insulation device manufacturing method flow chart provided in an embodiment of the present invention；
Fig. 3 is the structural schematic diagram of cryoablation needle provided in an embodiment of the present invention；
Fig. 4 is the schematic diagram that existing cryoablation needle natural torsion causes ectonexine pipe to be bonded.
Specific embodiment
With reference to the accompanying drawings and examples, technical solution of the present invention is further described.
Referring to Fig. 1, vacuum heat-insulation device provided in an embodiment of the present invention includes thermal insulator outer tube 1 and thermal insulator inner tube 5；
1 set of thermal insulator outer tube in thermal insulator inner tube 5, thermal insulator outer tube 1 and the 5 both ends vacuum welding of thermal insulator inner tube are close
Envelope makes to form vacuum cavity 2 between thermal insulator outer tube 1 and thermal insulator inner tube 5；It is provided on 5 outer wall of thermal insulator inner tube
High-temperature resistant fiber layer 3；Powdery getter 4 is equably provided on high-temperature resistant fiber layer 3；High-temperature resistant fiber layer 3 and powdery air-breathing
Agent 4 is respectively positioned in vacuum cavity 2.
In practical applications, the difference of 1 outer diameter of thermal insulator outer tube and 5 outer diameter of thermal insulator inner tube is less than or equal to 0.6mm,
And 1 length of thermal insulator outer tube is 1mm-6mm smaller than 5 length of thermal insulator inner tube；Thermal insulator outer tube 1 and thermal insulator inner tube
5 are all made of stainless steel capillary；High-temperature fibre can be the asbestos fibre or ceramic fibre of low thermal conductivity.
In practical applications, the vacuum degree with higher of vacuum cavity 2, in this way can effectively intercept heat transmission,
Play heat-insulated effect.High-temperature resistant fiber layer 3 is clipped between thermal insulator inner tube 5 and thermal insulator outer tube 1, in this way vacuum every
When hot device is bent, thermal insulator inner tube 5 can not be contacted with thermal insulator outer tube 1, so that the vacuum heat-insulation that vacuum cavity 2 plays is still
So effectively；Due to high-temperature fibre very thin (diameter about 0.02mm or so) and thermal coefficient it is low (pyroconductivity by contact area and
The thermal coefficient of Heat Conduction Material determines that the smaller pyroconductivity of contact area is poorer, and the thermal coefficient of Heat Conduction Material gets over low-heat biography
Conductance is poorer), thus it is very small by the heat or cooling capacity of high-temperature fibre conduction, to play good heat-blocking action.Powder
Shape getter 4 can (vacuum degree be up to 10 with the vacuum degree of raising vacuum cavity 2 in the short time-4It is more than pa), make vacuum heat-insulation device
Certain vacuum degree is maintained during storage and work, and then prevents the vacuum degree of vacuum cavity 2 from declining as time goes by；
In addition, powdery getter 4 can also eliminate gas that is remaining and discharging again after the exhaust sealed-off of vacuum heat-insulation device, in this way
Be conducive to shorten evacuation time.
It should be understood that heat insulation is determined by the thermal coefficient of heat-barrier material, it is various that heat transmitting is that high-temperature region passes through
Medium is propagated to low-temperature space, for the purpose of reaching thermal balance；Vacuum is by the various media isolation discharge in a fixed space, place
Heat source under vacuum conditions is not because can not carry out heat propagation for the medium of heat transfer；Vacuum degree and thermal coefficient
It is inversely proportional, that is to say, that vacuum degree is higher, and thermal coefficient is lower；Therefore, vacuum heat-insulation is the best heat-insulated side of heat insulation
Formula.The feature good using vacuum heat-insulation effect of the embodiment of the present invention, will set between thermal insulator outer tube 1 and thermal insulator inner tube 5
Count into vacuum cavity.
Vacuum heat-insulation device provided in an embodiment of the present invention has many advantages, such as that compact, vacuum heat-insulation effect are good, can be extensive
Heat-insulated processing applied to various miniature device/equipment.
Referring to Fig. 1 and Fig. 2, the embodiment of the invention provides the manufacturing method of above-mentioned vacuum heat-insulation device, include the following steps:
Step S1: the first stainless steel capillary is placed in vacuum brazing furnace, and the heating anneal under condition of high vacuum degree.
The temperature of first stainless steel capillary heating anneal under condition of high vacuum degree is 600-900 DEG C；At high annealing
The first stainless steel capillary can soften after managing and cooling down at a slow speed, prepare for the necking of subsequent handling.
Step S2: by after annealing the first stainless steel capillary and the second stainless steel capillary carry out electronickelling processing.
It is that guarantee is subsequent true by the purpose that the first stainless steel capillary and the second stainless steel capillary carry out electronickelling processing
Soldering flux can obtain good attachment when sky soldering.
Step S3: the outer wall of electronickelling treated the second stainless steel capillary is wound into high-temperature fibre, and in resistance to height
Powdery getter is equably sprinkled on warm fiber.
The high-temperature fibre of the embodiment of the present invention includes the asbestos fibre or ceramic fibre of low thermal conductivity.In vacuum device
Over time, metal pipe-wall has gas evolution causes its vacuum degree to decline to the vacuum degree in portion, and then under heat-insulating capability
Drop.It is found in practice, the time of making the product shank of longer cryoablation needle is more prone to produce frostbite.Powdery of the embodiment of the present invention is inhaled
Gas agent can (vacuum degree be up to 10 with the vacuum degree of raising vacuum cavity in the short time-4It is more than pa), storing vacuum heat-insulation device
With certain vacuum degree is maintained during work, and then prevent the vacuum degree of vacuum cavity from declining as time goes by.The present invention
The getter that embodiment uses is nonevaporable getter, such as zirconium vanadium iron nonevaporable getter, and zirconium vanadium iron non-evaporable is inhaled
Gas agent is a kind of nonevaporable getter of low-temp activation, there is excellent inspiratory effects at room temperature, will not be gone out at high temperature
Existing sintering phenomenon, realizes condition of high vacuum degree.
Step S4: by the first Stainless Steel Capillary pipe sleeve on the second stainless steel capillary.
Step S5: the first stainless steel capillary both ends are subjected to necking processing, and use soldering flux by the first stainless steel wool
Tubule and the second stainless steel capillary both ends vacuum welding seal.
In practical applications, using necking equipment by the first stainless steel capillary both ends necking, and guarantee the first stainless steel
Internal diameter after the necking of capillary both ends is equal with the outer diameter of the second stainless steel capillary.
Existing frequently-used soldering flux has thousands of kinds, it is necessary first to which selection can satisfy the soldering flux required as follows: 1) resistance to low
Temperature, because the work of cryoablation needle is at -150 DEG C；2) can adhere to well with stainless steel；3) ductility is good, because freezing disappears
When melting needle work, the temperature of the second stainless steel capillary of internal layer is -150 DEG C, and the temperature of the first stainless steel capillary of outer layer is behaved
37 DEG C of body temperature, 180-190 DEG C of difference of ectonexine tube temperature, it is huge that such temperature difference will lead to the pulling force that ectonexine pipe expands with heat and contract with cold, such as
The ductility of fruit soldering flux is not good enough, will lead to welding seam breaking, loses vacuum degree.By a large number of experiments, auri soldering flux is selected.
The existing very long usage history of auri solder, has many advantages, such as strong corrosion stability, good fluidity and wetability.Auri solder and base material
Effect degree it is small, wettability is good.The high temperature low temperature intensity of connector, extensibility, anti-oxidant, corrosion resistance is good, can be widely used for
Soldering when high vacuum series product.Secondly select soldering flux shape, the shape of soldering flux include sheet, filiform, powdery and
Paste etc..It is best by testing soldering flux paste since inner tube and outer tube are very thin (diameter about 1mm or so).Paste
Soldering flux can be very good to be sticked to commissure, it is not easy to fall off cause welding fail.Accordingly, the embodiment of the present invention selects paste
Auri soldering flux 6, as shown in Figure 1.
First stainless steel capillary and the second stainless steel capillary both ends commissure are smeared into 3/4ths circles (as shown in figure 1
Shown in appended drawing reference 7) auri soldering flux 6 paste.It should be understood that auri soldering flux paste can only smear 3/4ths
Circle, there are a quarter circles；Because auri soldering flux 6 paste can hinder very after whole circle smearing in vacuum brazing furnace welding
Air discharge in dead level, causes welding to fail.
The first stainless steel capillary after auri soldering flux paste will be smeared and the second stainless steel capillary lies in stone
On black pallet, and a quarter circle is made not smear being directed downward for auri soldering flux paste, in this way when auri soldering flux melts
Afterwards due to the effect of gravity and surface tension of liquid, the auri soldering flux of thawing can fill up entire weld seam.It is noted that
Selection graphite pallet holds the vacuum heat-insulation device for preparing welding, and cannot select stainless steel pallet；Although stainless steel fusing point is reachable
1200 DEG C, but metal stresses can be discharged in heating process cause to deform, and then move welding workpiece, cause welding to be lost
It loses.
Graphite pallet is put into vacuum brazing furnace, and is warming up to 860 DEG C under vacuum conditions.The vacuum of vacuum brazing furnace
Degree is less than equal to 10-4Pa, preferred vacuum degree are 10-5Pa.Since the component ratio of auri soldering flux is different, usually weld
Temperature heats up at 860 DEG C or so, therefore in the following way: being warming up to 500 DEG C first with 300 DEG C/h of heating rate, so
30 minutes are kept the temperature at 500 DEG C afterwards, pipe is allowed to be heated evenly；800 DEG C are warming up to from 500 DEG C with 150 DEG C/h of heating rate again,
Then 30 minutes are kept the temperature；860 degree are warming up to from 800 DEG C with 150 DEG C/h of heating rate again, keeps the temperature 10 minutes.It was heating up
After the completion of journey, into vacuum brazing furnace, inflated with nitrogen accelerates cooling rate when being naturally cooling to 300 DEG C, when temperature in vacuum brazing furnace
When lower than 50 DEG C, graphite pallet is taken out in blow-on.
Referring to Fig. 1 and Fig. 3, the embodiment of the invention also provides the cryoablation needle being made of above-mentioned vacuum heat-insulation device, packets
Include probe bodies 12, appendix 11, vacuum heat-insulation device 9 and heat exchanger 10；Vacuum heat-insulation device 9 is arranged before probe bodies 12
End；Heat exchanger 10 is arranged in 12 rear end of probe bodies；Appendix 11 passes through heat exchanger 10 and vacuum heat-insulation device 9；Appendix
11 output end is provided with throttle orifice 8；Vacuum heat-insulation device 9 includes thermal insulator outer tube 1 and thermal insulator inner tube 5；Outside thermal insulator
In thermal insulator inner tube 5, thermal insulator outer tube 1 and the 5 both ends vacuum welding of thermal insulator inner tube seal 1 set of pipe of layer, make heat-insulated
Vacuum cavity 2 is formed between device outer tube 1 and thermal insulator inner tube 5；High-temperature fibre is provided on 5 outer wall of thermal insulator inner tube
Layer 3；Powdery getter 4 is equably provided on high-temperature resistant fiber layer 3；High-temperature resistant fiber layer 3 and powdery getter 4 are respectively positioned on very
In cavity body 2.
The working method of cryoablation needle of the embodiment of the present invention: high pressure argon gas is entered inside heat exchanger 10 by appendix 11
And flow through, 8 ejector refrigeration of throttle orifice is reached, the low-pressure low-temperature argon gas of reflux reaches heat by the inner tube of vacuum heat-insulation device 9 and hands over
The external helicoid fin of parallel operation 10, spiral channel flows out between helical fin and shell, and to newly flowing into appendix 11
It is discharged into atmosphere after high pressure argon gas pre-cooling.
Cryoablation needle is very thin in actual use, and general diameter only has 1-2mm, and tube wall is again very thin, due to its own and
The weight of its pipeline will lead to the natural torsion of needle, it is difficult to ensure that absolute straightness；Have again since needle is very thin, vacuum heat-insulation device
Ectonexine pipe select stainless steel capillary be used as material, the distance between ectonexine very little only have about 0.2mm or so, other than
The outer layer stainless steel that the natural torsion in portion will lead to internal vacuum heat-insulation device is sticked with internal layer stainless steel to be contacted (in referring to fig. 4
Appended drawing reference 13), so that heat (cooling capacity) can be conducted from ectonexine contact position, leads to the heat-insulated failure in this part, as a result go out
Existing frostbite.Due to the complexity of operation and the radio radiation of CT, clinician can not can guarantee its straight straightness when performing the operation,
Therefore vacuum heat-insulation device ectonexine pipe sticks in order to prevent, and the embodiment of the present invention is provided with high-temperature fibre between ectonexine,
This fiber will not change characteristic at high temperature brazing (900 DEG C or so), in this way when cryoablation needle bends, high temperature resistant
Fiber, which can be clipped between ectonexine pipe, contact ectonexine can not, and ectonexine pipe will not stick, so that vacuum heat-insulation is still effective；
Simultaneously because thermal coefficient is low in addition for high-temperature fibre very thin (diameter about 0.02mm or so), conducted by high-temperature fibre cold
Amount is very small, reaches good heat-blocking action.
The shank partial interior of cryoablation needle of the embodiment of the present invention has vacuum heat-insulation device, to reach cold inside isolation shank
Amount conduction outward, prevents shank surface from generating low temperature.At room temperature pass through experiments have shown that, when cryoablation needle work when, needle
Bar surface temperature may remain in 10 DEG C or more always.
Existing cryoablation needle generally will appear the bad phenomenon of heat insulation after factory 1 year, the reason is that its vacuum degree
Decline as time goes by, and the embodiment of the present invention uses powdery getter that can make to freeze to improve vacuum degree in the short time
Ablation needle maintains certain vacuum degree during storage and work.When being performed the operation using cryoablation needle, freezing starts rank
Section has a preferable heat insulation, but using one after the meeting can heat-insulated failure suddenly, the reason for this is that weld bond bursts apart, and the present invention is implemented
Example has well solved the pulling force problem expanded with heat and contract with cold using auri solder flux, avoids weld bond and bursts apart.Existing cryoablation needle exists
It fails once natural torsion is heat-insulated in use process, the reason for this is that ectonexine stainless steel tube is sticked together and is caused, and it is of the invention
Embodiment uses the high-temperature fibre of low thermal conductivity, the fitting of ectonexine stainless steel tube when avoiding natural torsion, so that very
It is empty heat-insulated still effective, so that frostbite skin will not be caused, improve needle point freezing efficiency.Freezing provided in an embodiment of the present invention
Ablation needle improves safety, the validity of cryoablation.
The embodiment of the present invention solves the problems, such as the shank frostbite of cryoablation needle using vacuum heat-insulation technology, solves simultaneously
Shank natural torsion leads to heat-insulated ectonexine contact conduction cooling capacity, and improve vacuum degree and prevent vacuum heat-insulation device with when
Between passage the problem of causing vacuum degree to decline.
Particular embodiments described above has carried out further in detail the purpose of the present invention, technical scheme and beneficial effects
It describes in detail bright, it should be understood that the above is only a specific embodiment of the present invention, is not intended to restrict the invention, it is all
Within the spirit and principles in the present invention, any modification, equivalent substitution, improvement and etc. done should be included in guarantor of the invention
Within the scope of shield.
Claims (13)
1. a kind of vacuum heat-insulation device, which is characterized in that including thermal insulator outer tube and thermal insulator inner tube；The thermal insulator outer layer
In the thermal insulator inner tube, the thermal insulator outer tube and the both ends vacuum welding of thermal insulator inner tube seal pipe sleeve, make institute
It states and forms vacuum cavity between thermal insulator outer tube and thermal insulator inner tube；Resistance to height is provided in the thermal insulator internal layer pipe outer wall
Warm fibrous layer；Powdery getter is equably provided on the high-temperature resistant fiber layer；The high-temperature resistant fiber layer and powdery air-breathing
Agent is respectively positioned in the vacuum cavity.
2. vacuum heat-insulation device as described in claim 1, which is characterized in that the thermal insulator outer layer pipe outside diameter and the thermal insulator
The difference of internal layer pipe outside diameter is less than or equal to 0.6mm.
3. vacuum heat-insulation device as described in claim 1, which is characterized in that the thermal insulator outer layer length of tube is than the thermal insulator
The small 1mm-6mm of internal layer length of tube.
4. vacuum heat-insulation device as described in claim 1, which is characterized in that the thermal insulator outer tube and thermal insulator inner tube are equal
For stainless steel capillary.
5. a kind of vacuum heat-insulation device manufacturing method as described in claim 1 characterized by comprising
First stainless steel capillary is placed in vacuum brazing furnace, and the heating anneal under condition of high vacuum degree；
By after annealing the first stainless steel capillary and the second stainless steel capillary carry out electronickelling processing；
The outer wall of electronickelling treated the second stainless steel capillary is wound into high-temperature fibre, and on the high-temperature fibre
Equably sprinkle getter；
By the first Stainless Steel Capillary pipe sleeve on second stainless steel capillary；
First stainless steel capillary both ends are subjected to necking processing, and use soldering flux by first stainless steel capillary
It is sealed with the second stainless steel capillary both ends vacuum welding.
6. vacuum heat-insulation device manufacturing method as claimed in claim 5, which is characterized in that the temperature of the annealing is 600-900
℃；The high-temperature fibre includes the asbestos fibre or ceramic fibre of low thermal conductivity；The getter is non-evaporable getter
Agent, including zirconium vanadium iron nonevaporable getter.
7. vacuum heat-insulation device manufacturing method as claimed in claim 5, which is characterized in that first stainless steel capillary both ends
Carrying out necking, treated that internal diameter is equal with the outer diameter of second stainless steel capillary.
8. vacuum heat-insulation device manufacturing method as claimed in claim 5, which is characterized in that described to use soldering flux by described first
The step of stainless steel capillary is sealed with the second stainless steel capillary both ends vacuum welding include:
3/4ths circle soldering fluxes are smeared in first stainless steel capillary and the second stainless steel capillary both ends commissure；
The first stainless steel capillary after soldering flux will be smeared and the second stainless steel capillary is lain on graphite pallet, and makes four
/ mono- circle does not smear being directed downward for soldering flux；
The graphite pallet is put into vacuum brazing furnace, and is warming up to 860 DEG C under vacuum conditions；
When the vacuum brazing in-furnace temperature is lower than 50 DEG C, the graphite pallet is taken out.
9. vacuum heat-insulation device manufacturing method as claimed in claim 8, which is characterized in that the shape of the soldering flux includes piece
Shape, filiform, powdery and paste.
10. vacuum heat-insulation device manufacturing method as claimed in claim 9, which is characterized in that the soldering flux is auri soldering flux；
The shape of the auri soldering flux is paste.
11. vacuum heat-insulation device manufacturing method as claimed in claim 8, which is characterized in that the vacuum degree of the vacuum condition is small
In equal to 10-4Pa。
12. vacuum heat-insulation device manufacturing method as claimed in claim 8, which is characterized in that the step of being warming up to 860 DEG C tool
Body includes: to be warming up to 500 DEG C first with 300 DEG C/h of heating rate, keeps the temperature 30 minutes；Then with 150 DEG C/h of liter
Warm speed is warming up to 800 DEG C, keeps the temperature 30 minutes；860 DEG C finally are warming up to 150 DEG C/h of heating rate, keeps the temperature 10 points
Clock.
13. a kind of cryoablation needle, which is characterized in that including probe bodies, appendix, vacuum heat-insulation device and heat exchanger；Institute
Vacuum heat-insulation device is stated to be arranged in the probe bodies front end；The heat exchanger is arranged in the probe bodies rear end；It is described defeated
Tracheae passes through the heat exchanger and vacuum heat-insulation device；The output end of the appendix is provided with throttle orifice；The vacuum heat-insulation
Device includes thermal insulator outer tube and thermal insulator inner tube；The thermal insulator outer pipe sleeve is described in the thermal insulator inner tube
Thermal insulator outer tube and the both ends vacuum welding of thermal insulator inner tube seal, make the thermal insulator outer tube and thermal insulator inner tube it
Between form vacuum cavity；High-temperature resistant fiber layer is provided in the thermal insulator internal layer pipe outer wall；On the high-temperature resistant fiber layer
It is provided with powdery getter evenly；The high-temperature resistant fiber layer and powdery getter are respectively positioned in the vacuum cavity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910510179.8A CN110200696A (en) | 2019-06-13 | 2019-06-13 | Vacuum heat-insulation device, its manufacturing method and cryoablation needle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910510179.8A CN110200696A (en) | 2019-06-13 | 2019-06-13 | Vacuum heat-insulation device, its manufacturing method and cryoablation needle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110200696A true CN110200696A (en) | 2019-09-06 |
Family
ID=67792483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910510179.8A Pending CN110200696A (en) | 2019-06-13 | 2019-06-13 | Vacuum heat-insulation device, its manufacturing method and cryoablation needle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110200696A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021051391A1 (en) * | 2019-09-16 | 2021-03-25 | 海杰亚（北京）医疗器械有限公司 | Cryogenic-thermal ablation needle |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN203476314U (en) * | 2013-07-26 | 2014-03-12 | 武汉海王机电工程技术公司 | Probe vacuum flask of element capture spectrum logging instrument |
| CN104696669A (en) * | 2013-12-10 | 2015-06-10 | 三星电子株式会社 | Vacuum insulation panel |
| CN105215498A (en) * | 2015-10-30 | 2016-01-06 | 西安航天发动机厂 | The gas pressurized diffusion soldering method of a kind of steel-steel cooling sandwith layer form workpiece |
| CN206044717U (en) * | 2016-07-11 | 2017-03-29 | 北京阳光易帮医疗科技有限公司 | A kind of cryoprobe |
| CN208511163U (en) * | 2017-08-08 | 2019-02-19 | 湖南盈博医疗科技有限公司 | Cryoablation treatment puncture needle |
| CN208693430U (en) * | 2017-11-27 | 2019-04-05 | 海杰亚（北京）医疗器械有限公司 | Cryoablation needle and its syringe needle |
-
2019
- 2019-06-13 CN CN201910510179.8A patent/CN110200696A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN203476314U (en) * | 2013-07-26 | 2014-03-12 | 武汉海王机电工程技术公司 | Probe vacuum flask of element capture spectrum logging instrument |
| CN104696669A (en) * | 2013-12-10 | 2015-06-10 | 三星电子株式会社 | Vacuum insulation panel |
| CN105215498A (en) * | 2015-10-30 | 2016-01-06 | 西安航天发动机厂 | The gas pressurized diffusion soldering method of a kind of steel-steel cooling sandwith layer form workpiece |
| CN206044717U (en) * | 2016-07-11 | 2017-03-29 | 北京阳光易帮医疗科技有限公司 | A kind of cryoprobe |
| CN208511163U (en) * | 2017-08-08 | 2019-02-19 | 湖南盈博医疗科技有限公司 | Cryoablation treatment puncture needle |
| CN208693430U (en) * | 2017-11-27 | 2019-04-05 | 海杰亚（北京）医疗器械有限公司 | Cryoablation needle and its syringe needle |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021051391A1 (en) * | 2019-09-16 | 2021-03-25 | 海杰亚（北京）医疗器械有限公司 | Cryogenic-thermal ablation needle |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5490218B2 (en) | Single phase liquid refrigerant refrigeration ablation system having a multi-tube distal portion and associated method | |
| EP2273945B1 (en) | System for cryoablation treatment | |
| EP1435825B1 (en) | Malleable cryosurgical probe | |
| US9554842B2 (en) | Cryoprobe for low pressure systems | |
| US6767346B2 (en) | Cryosurgical probe with bellows shaft | |
| US8162929B2 (en) | Cryoablation segment for creating linear lesions | |
| US5993444A (en) | Method and device for trans myocardial cryo revascularization | |
| US6074412A (en) | Cryoprobe | |
| WO2006006989A2 (en) | System and method for varying return pressure to control tip temperature of a cryoablation catheter | |
| US20050016188A1 (en) | Distal end for cryoablation catheters | |
| JP2022527172A (en) | Cryoprobe | |
| CN110200696A (en) | Vacuum heat-insulation device, its manufacturing method and cryoablation needle | |
| JP7201799B2 (en) | Cryoprobe with reinforcement element | |
| JP6694937B2 (en) | Heart surgery cryoprobe | |
| US20050198972A1 (en) | Pressure-temperature control for a cryoablation catheter system | |
| CN109481001A (en) | A kind of cryogenic liquid formula cryoablation equipment | |
| US8298220B2 (en) | Cryoprobe with coaxial chambers | |
| CN204618397U (en) | A kind of cryotherapy probe | |
| US20070149958A1 (en) | Cryoprobe with exhaust heater | |
| WO2008077317A1 (en) | Radio frequency ablation system with joule-thomson cooler | |
| JP7476294B2 (en) | Cryoprobe with stiffening element | |
| AU754411B2 (en) | Cryoprobe |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20190906 |
|
| WD01 | Invention patent application deemed withdrawn after publication |