CN110178833A - A kind of tissue storage device for liquid nitrogen frozen - Google Patents

A kind of tissue storage device for liquid nitrogen frozen Download PDF

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Publication number
CN110178833A
CN110178833A CN201910539682.6A CN201910539682A CN110178833A CN 110178833 A CN110178833 A CN 110178833A CN 201910539682 A CN201910539682 A CN 201910539682A CN 110178833 A CN110178833 A CN 110178833A
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CN
China
Prior art keywords
drawer
hanger body
storage device
hole
tissue storage
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CN201910539682.6A
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Chinese (zh)
Inventor
李友筑
李娜
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Individual
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Individual
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Publication date
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Priority to CN201910539682.6A priority Critical patent/CN110178833A/en
Publication of CN110178833A publication Critical patent/CN110178833A/en
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Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0236Mechanical aspects
    • A01N1/0263Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
    • A01N1/0268Carriers for immersion in cryogenic fluid, both for slow-freezing and vitrification, e.g. open or closed "straws" for embryos, oocytes or semen

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Mechanical Engineering (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The present invention relates to a kind of tissue storage devices for liquid nitrogen frozen, including a hanger body, it is installed in the hanging rod and spacer pin of the hanger body, there are the multiple drawer chambers being set in sequence along its length in the hanger body, the intracavitary all drawers with peripheral wall and bottom surface of each drawer, it is all separated out on each drawer multiple for placing the accommodating cavity of freezer storage pipe, it is formed in the hanger body and drawer so that the runner that each accommodating cavity is all connected to hanger body outside, the spacer pin is mounted in the hanger body and limits the drawer and deviate from from the drawer chamber, to solve the problems, such as existing freezer storage canal float on liquid nitrogen.

Description

A kind of tissue storage device for liquid nitrogen frozen
Technical field
The present invention relates to tissue stored frozen fields, are specifically related to a kind of tissue storage device for liquid nitrogen frozen.
Background technique
In the reproductive medicine section of various big hospital, often used liquid nitrogen container comes to sperm, embryo or the ovum to people Carry out vital preservation.In stored frozen, usually first sperm, embryo or ovum are deposited in freezer storage pipe, then again By liquid nitrogen pour into in freezer storage pipe with to sperm, embryo or egg freezing, it is finally that the freezer storage pipe of liquid filling nitrogen is direct It is placed in liquid nitrogen container in carrying out and maintains extremely low temperature, to realize vital preservation.Freezer storage pipe, which is placed directly in liquid nitrogen container, to be existed Following problems:
1, freezer storage pipe, which is placed directly in liquid nitrogen container, to swim on liquid nitrogen, cause freezer storage pipe complete with liquid nitrogen Full connected, this makes sperm, embryo or ovum in freezer storage pipe there is a possibility that inactivation.
2, freezer storage canal float is on liquid nitrogen, and when carrying out liquid nitrogen supplement, liquid nitrogen can wash away freezer storage pipe, cause cold It freezes the label being sticked on storage tube wall to be easy to fall off, so as to cause sperm, embryo or the ovum that can not recognize freezer storage pipe Ownership.
3, due to that can store many freezer storage pipes in liquid nitrogen container, by special tool tong by freezer storage pipe when taking-up Go out from liquid nitrogen container inner clip, but clamping when, the label being sticked on freezer storage tube wall is difficult to distinguish, therefore clamps often Non-targeted object can often be taken out, it is also possible to will affect the activity of sperm in freezer storage pipe, embryo or ovum.
Summary of the invention
The present invention is intended to provide a kind of tissue storage device for liquid nitrogen frozen, to solve existing freezer storage pipe drift Float on the problem on liquid nitrogen.
Concrete scheme is as follows:
A kind of tissue storage device for liquid nitrogen frozen including a hanger body, is installed in an extension of the hanger body Bar and spacer pin, have the multiple drawer chambers being set in sequence along its length in the hanger body, and each drawer is intracavitary All there is a drawer of peripheral wall and bottom surface, multiple accommodating cavities for being used to place freezer storage pipe are all separated out on each drawer, It is formed in the hanger body and drawer so that the runner that each accommodating cavity is all connected to hanger body outside, the spacer pin It is mounted in the hanger body and limits the drawer and deviate from from the drawer chamber.
Further, the hanger body includes a rectangular frame and multiple first partitions, multiple first partitions Rectangular frame is separated into multiple multiple drawer chambers being set in sequence along the rectangular frame length direction, the pumping intracavitary positioned at drawer There is gap, the gap is as the runner between drawer and the inner wall of the drawer chamber.
Further, it is provided in the end face at rectangular frame length both ends and multiple first partitions multiple First through hole is provided with multiple second through-holes on the bottom surface of the drawer, when the drawer be located at drawer it is intracavitary when, described first Through-hole and the second through-hole face are arranged.
Further, there is convex block, which will be in the first partition on the bottom surface of the first partition and/or drawer It raises the bottom surface of the drawer.
Further, multiple second partitions being staggered are provided in the drawer, the second partition is by the drawer The multiple accommodating cavities being arranged in multiple lines and multiple rows are inside separated into, are additionally provided with multiple third through-holes on the second partition, the third Through-hole is so that accommodating cavity is connected to adjacent accommodating cavity.
Further, a third through-hole, and each third through-hole are provided in the middle part of the intersection of the second partition Surrounding four accommodating cavities are connected to.
Further, the rectangular frame of the hanger body includes the both side plate being oppositely arranged and top plate and bottom plate, and two Side plate all has the flanging toward inner bending on one end of width direction, and the flanging as all drawer chambers and drawer chamber to be open Opposite side wall.
Further, on the top and bottom of the hanger body have extend to drawer chamber opening outside the first otic placode with And second otic placode, all have the fourth hole of face setting on first otic placode and the second otic placode, on first otic placode also With the fifth hole for being located at fourth hole side, the spacer pin includes a pin rod and the elasticity as made of pin rod bending Card division, the pin rod passes through the fourth hole of first otic placode and the second otic placode, and elastic card division is caught in the described 5th In through-hole.
Further, the inner wall of the drawer chamber opposite sides is provided with a circular arc pit on being located at its opening, There is the circular arc salient point for the setting that matches with the circular arc pit on the outer wall of the drawer, when the drawer pulls out, the circle Arc salient point can be caught in preventing the drawer from being completely pulled out of in the circular arc pit.
Further, the hanger body, hanging rod, spacer pin and drawer are made of stainless steel material.
A kind of tissue storage device for liquid nitrogen frozen provided by the invention has following excellent compared with prior art Point: freezer storage pipe is first placed in the drawer of hanger body by tissue storage device provided by the invention, is then stored up with the tissue Cryopreservation device is immersed in liquid nitrogen together, therefore freezer storage pipe will not be swum on the liquid level of liquid nitrogen, and while submergence, Liquid nitrogen can also flow into each accommodating cavity, maintain its extremely low temperature to the freezer storage pipe being put into accommodating cavity, to realize Vital preservation.
And freezer storage pipe is placed in the accommodating cavity of drawer, and when adding liquid nitrogen, liquid nitrogen will not wash away freezer storage Pipe, therefore the label on freezer storage pipe will not fall off.
When needing to take out freezer storage pipe, which is entirely taken out from liquid nitrogen container, it then will limit Position pin is removed, then the target freezer storage pipe in corresponding drawer is taken out, therefore can fast and accurately freeze target Storage tube takes out.
Detailed description of the invention
Fig. 1 shows the stereoscopic schematic diagram of tissue storage device.
Fig. 2 shows the stereoscopic schematic diagrams of hanger body.
Fig. 3 shows the stereoscopic schematic diagram of drawer.
Fig. 4 shows the top view of drawer.
Fig. 5 shows the stereoscopic schematic diagram of second partition.
Fig. 6 shows the stereoscopic schematic diagram of snap-gauge.
Fig. 7 shows the stereoscopic schematic diagram on another view direction of hanger body.
Fig. 8 shows the schematic diagram that the circular arc salient point on the circular arc pit and drawer of hanger body matches.
Specific embodiment
To further illustrate that each embodiment, the present invention are provided with attached drawing.These attached drawings are that the invention discloses one of content Point, mainly to illustrate embodiment, and the associated description of specification can be cooperated to explain the operation principles of embodiment.Cooperation ginseng These contents are examined, those of ordinary skill in the art will be understood that other possible embodiments and advantages of the present invention.In figure Component be not necessarily to scale, and similar component symbol is conventionally used to indicate similar component.
Now in conjunction with the drawings and specific embodiments, the present invention is further described.
It is as shown in FIG. 1 to FIG. 3, present embodiments provide a kind of tissue storage device for liquid nitrogen frozen, tissue storage Cryopreservation device includes a hanger body 1, the hanging rod 2 and spacer pin 3 for being installed in the hanger body 1.
Wherein, the lower end of hanging rod 2 and the hanger body 1 are fixed, and upper end is hook, can hang over the week of liquid nitrogen container opening On edge.
There are the multiple drawer chambers 10 being set in sequence along its length in hanger body 1, all have in each drawer chamber 10 There is a drawer 4 of peripheral wall and bottom surface, multiple accommodating cavities 40 for being used to place freezer storage pipe be all separated out on each drawer 4, And formed on hanger body 1 and drawer 4 so that each accommodating cavity 40 all with the runner that is connected to outside hanger body 1 so that The hanger body 1 is placed in liquid nitrogen container submerged by liquid nitrogen after, liquid nitrogen can be flowed by the runner in each accommodating cavity 40, with right It is put into the freezer storage pipe in accommodating cavity 40 and maintains its extremely low temperature, to realize vital preservation.And spacer pin 3 is then mounted on hanger It limits drawer 4 on ontology 1 and deviates from from drawer chamber 10, drop out freezer storage pipe to prevent drawer 4 from skidding off.
Need it is clear that, hanger body 1, hanging rod 2, spacer pin 3 and the drawer 4 of the tissue storage device by can be long when Between stored in liquid nitrogen without or the material that is not easily deteriorated be made, in examining for the factors such as simplicity, the material cost of production Under amount, hanger body 1, hanging rod 2, spacer pin 3 and drawer 4 select stainless steel material to be made.
When carrying out vital preservation, which is soaked together together with the freezer storage pipe being placed in drawer 4 Not in liquid nitrogen, freezer storage pipe will not be swum on the liquid level of liquid nitrogen, and while submergence, liquid nitrogen can also be flowed into In each accommodating cavity 40, its extremely low temperature is maintained to being put into the freezer storage pipe in accommodating cavity 40, to realize vital preservation.And Freezer storage pipe is placed in the accommodating cavity 40 of drawer 4, and when adding liquid nitrogen, liquid nitrogen will not wash away freezer storage pipe, therefore cold The label frozen on storage tube will not fall off.When needing to take out freezer storage pipe, by the tissue storage device entirely from liquid nitrogen It takes out in tank, then removes spacer pin 3, then the target freezer storage pipe in corresponding drawer is taken out, therefore can be fast Speed, accurately by target freezer storage pipe take out.
In the present embodiment, with reference to Fig. 1-Fig. 3, hanger body 1 includes a rectangular frame 11 and multiple first partitions 12, The rectangular frame 11 is separated into multiple multiple pumpings being set in sequence along 11 length direction of rectangular frame by multiple first partitions 12 Drawer chamber 10, drawer 4 in drawer chamber 10 and has gap between the inner wall of the drawer chamber 10, the gap is as on drawer The runner being connected to outside each accommodating cavity 40 and hanger body.I.e. liquid nitrogen can be from the gap between drawer 4 and drawer chamber 10 It flows into drawer.
It is preferred in the present embodiment, with reference to Fig. 1-Fig. 4, the end face at 11 length both ends of rectangular frame and multiple first partitions It is provided with multiple first through hole 100 on 12, multiple second through-holes 42 are also equipped on the bottom surface of drawer 4.It is taken out when drawer 4 is located at When in drawer chamber 10, first through hole 100 and 42 face of the second through-hole are arranged, so that liquid nitrogen can be from first through hole 100 and second Through-hole 42 flows into the accommodating cavity 40 on drawer 4.
It is preferred in the present embodiment, there is convex block on the bottom surface of first partition 12 and/or drawer 4, the convex block by this first It raises the bottom surface of drawer 4 on partition 12.Referring to figs. 2 and 3, in the present embodiment, convex block is respectively to be located at first partition 12 Flanging 120 at drawer mouth and the raised line 44 on 4 bottom surface of drawer, on drawer 4 is located in drawer chamber 10, flanging 120 It is located at raised line 44 on the opposite end of 4 bottom surface of drawer, the bottom surface of the drawer 4 is raised, is i.e. the bottom surface of drawer 4 and Between one partition 12 and non-direct contact, and there is certain gap, in order to which liquid nitrogen is from the second through-hole 42 of 4 bottom surface of drawer It is flowed into the accommodating cavity 40 on drawer 4.
It is preferred in the present embodiment, with reference to Fig. 3-Fig. 5, multiple second partitions 46 being staggered are provided in drawer 4, it should Second partition 46 will be separated into the multiple accommodating cavities 40 being arranged in multiple lines and multiple rows in drawer 4, and be additionally provided on second partition 46 Multiple third through-holes 460, the third through-hole 460 is so that accommodating cavity 40 is connected to adjacent accommodating cavity 40, so that liquid nitrogen can be more Good flows into each accommodating cavity 40.Preferably, above-mentioned third through-hole 460 is set in the intersection of second partition 46 In portion, and surrounding four accommodating cavities 40 are connected to by each third through-hole.In this implementation, with reference to Fig. 6, second partition 46 by The interlaced setting of multiple snap-gauges 46 ' and obtain, there are several card slots 462 on each snap-gauge, and the bottom end of card slot 462 for greater than The expansion section 464 of the 46 ' thickness of snap-gauge, when two 46 ' interlaced grafting of snap-gauge, the expansion section 464 of 462 bottom end of card slot as with The third through-hole 460 that adjacent accommodating cavity 40 is connected to.
Preferred in the present embodiment, with reference to Fig. 7, the rectangular frame 11 of hanger body 1 includes the both side plate 110 being oppositely arranged And top plate 111 and bottom plate 112, both side plate 110 all have the flanging 1100 toward inner bending, the folding on one end of width direction Side 1100 as drawer chamber 10 and drawer chamber 10 to be open opposite side wall.I.e. the rectangular frame 11 is open separately with respect to drawer chamber 10 The side wall of side is hollow out setting, therefore liquid nitrogen can also flow into drawer 4 from the other side of the rectangular frame 11.
It is preferred in the present embodiment, with reference to Fig. 1 and Fig. 2, has on the top and bottom of hanger body 1 and extend to drawer chamber The first otic placode 13 and the second otic placode 14 outside 10 openings all have the of face setting on first otic placode 13 and the second otic placode 14 Four through-holes 130 also have the fifth hole 132 positioned at fourth hole side on first otic placode 13.Spacer pin 3 includes a pin rod 30 And the elasticity card division 31 as made of pin rod bending, wherein pin rod 30 across the first otic placode 13 and the second otic placode 14 the Four through-holes 130, and elastic card division 31 is caught in fifth hole 132, drawer 4 is blocked and makes all drawers 4 by pin rod 30 It can not deviate from from drawer chamber 10, so that guaranteeing that drawer can not be from abjection when the tissue storage device is immersed in liquid nitrogen.
Preferred in the present embodiment, with reference to Fig. 8, the inner wall of 10 opposite sides of drawer chamber is respectively provided on being located at its opening There is a circular arc pit 1101, there is the circular arc salient point 47 for the setting that matches with the circular arc pit 1101 on the outer wall of drawer 4, work as pumping When drawer 4 pulls out, circular arc salient point 47, which can be caught in in the circular arc pit 1101, prevents the drawer 4 from being completely pulled out of, to prevent Misoperation causes entire drawer 4 to be completely pulled out of when drawer 4 pulls out, and falls so as to cause the freezer storage pipe in drawer 4.
Although specifically showing and describing the present invention in conjunction with preferred embodiment, those skilled in the art should be bright It is white, it is not departing from the spirit and scope of the present invention defined by the appended claims, it in the form and details can be right The present invention makes a variety of changes, and is protection scope of the present invention.

Claims (10)

1. a kind of tissue storage device for liquid nitrogen frozen, it is characterised in that: including a hanger body, be installed in the hanger sheet A hanging rod and spacer pin for body has the multiple drawer chambers being set in sequence along its length in the hanger body, each Drawer is intracavitary all with a drawer of peripheral wall and bottom surface, is all separated out on each drawer multiple for placing freezer storage pipe Accommodating cavity, formed in the hanger body and drawer so that each accommodating cavity all with the runner that is connected to outside hanger body, institute Spacer pin is stated to be mounted in the hanger body and limit the drawer and deviate from from the drawer chamber.
2. tissue storage device according to claim 1, it is characterised in that: the hanger body include a rectangular frame with And rectangular frame is separated into and multiple sequentially sets along the rectangular frame length direction by multiple first partitions, multiple first partitions The multiple drawer chambers set, between the intracavitary drawer of drawer and the inner wall of the drawer chamber have gap, the gap be used as described in Runner.
3. tissue storage device according to claim 2, it is characterised in that: the end face at rectangular frame length both ends with And multiple first through hole are provided in multiple first partitions, multiple second through-holes are provided on the bottom surface of the drawer, When the drawer be located at drawer it is intracavitary when, the first through hole and the second through-hole face are arranged.
4. tissue storage device according to claim 3, it is characterised in that: the bottom surface of the first partition and/or drawer Upper to have convex block, which raises the bottom surface of the drawer in the first partition.
5. tissue storage device according to claim 2, it is characterised in that: be provided with multiple be staggered in the drawer Second partition, the second partition will be separated into the drawer in multiple lines and multiple rows be arranged multiple accommodating cavities, described second every Multiple third through-holes are additionally provided on plate, the third through-hole is so that accommodating cavity is connected to adjacent accommodating cavity.
6. tissue storage device according to claim 5, it is characterised in that: the middle part of the intersection of the second partition is equal It is provided with a third through-hole, and surrounding four accommodating cavities are connected to by each third through-hole.
7. tissue storage device according to claim 2, it is characterised in that: the rectangular frame of the hanger body includes phase Both side plate and top plate and bottom plate to setting, both side plate all have the flanging toward inner bending on one end of width direction, should Flanging as all drawer chambers and drawer chamber to be open opposite side wall.
8. tissue storage device according to claim 2, it is characterised in that: have on the top and bottom of the hanger body There is the first otic placode and the second otic placode extended to outside drawer chamber opening, all has face on first otic placode and the second otic placode The fourth hole of setting, also has the fifth hole positioned at fourth hole side on first otic placode, and the spacer pin includes One pin rod and the elasticity card division as made of pin rod bending, the pin rod across first otic placode and the second otic placode the Four through-holes, and elastic card division is caught in the fifth hole.
9. tissue storage device according to claim 2, it is characterised in that: the inner wall of the drawer chamber opposite sides is in place In being provided with a circular arc pit in its opening, there is the circle for the setting that matches with the circular arc pit on the outer wall of the drawer Arc salient point, when the drawer pulls out, the circular arc salient point, which can be caught in in the circular arc pit, prevents the drawer complete It is complete to pull out.
10. tissue storage device according to claim 1, it is characterised in that: the hanger body, hanging rod, spacer pin with And drawer is made of stainless steel material.
CN201910539682.6A 2019-06-21 2019-06-21 A kind of tissue storage device for liquid nitrogen frozen Pending CN110178833A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910539682.6A CN110178833A (en) 2019-06-21 2019-06-21 A kind of tissue storage device for liquid nitrogen frozen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910539682.6A CN110178833A (en) 2019-06-21 2019-06-21 A kind of tissue storage device for liquid nitrogen frozen

Publications (1)

Publication Number Publication Date
CN110178833A true CN110178833A (en) 2019-08-30

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CN201910539682.6A Pending CN110178833A (en) 2019-06-21 2019-06-21 A kind of tissue storage device for liquid nitrogen frozen

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106577633A (en) * 2016-12-06 2017-04-26 山东大学 Automatic semen refrigerating device
CN208365929U (en) * 2018-05-14 2019-01-11 青岛海高设计制造有限公司 Refrigerator and its freezer drawer
CN109601525A (en) * 2018-09-11 2019-04-12 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 Embryo cryopreservation carries bar and drawer type storage device
CN208755031U (en) * 2018-08-07 2019-04-19 云南省第一人民医院 Low-temperature storage device for reproductive medicine
CN210143686U (en) * 2019-06-21 2020-03-17 李友筑 Tissue storage device for liquid nitrogen freezing

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106577633A (en) * 2016-12-06 2017-04-26 山东大学 Automatic semen refrigerating device
CN208365929U (en) * 2018-05-14 2019-01-11 青岛海高设计制造有限公司 Refrigerator and its freezer drawer
CN208755031U (en) * 2018-08-07 2019-04-19 云南省第一人民医院 Low-temperature storage device for reproductive medicine
CN109601525A (en) * 2018-09-11 2019-04-12 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 Embryo cryopreservation carries bar and drawer type storage device
CN210143686U (en) * 2019-06-21 2020-03-17 李友筑 Tissue storage device for liquid nitrogen freezing

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Application publication date: 20190830

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