CN110141268A - A kind of machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe - Google Patents
A kind of machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe Download PDFInfo
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- CN110141268A CN110141268A CN201910376841.5A CN201910376841A CN110141268A CN 110141268 A CN110141268 A CN 110141268A CN 201910376841 A CN201910376841 A CN 201910376841A CN 110141268 A CN110141268 A CN 110141268A
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- Prior art keywords
- frequency
- intravascular ultrasound
- rotating type
- imaging probe
- piezoelectric
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0891—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/12—Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
- A61B8/4444—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
- A61B8/4477—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device using several separate ultrasound transducers or probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
- A61B8/4483—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/485—Diagnostic techniques involving measuring strain or elastic properties
Abstract
The present invention discloses a kind of machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe, the double-deck double frequency piezoelectric ultrasonic transducer architecture is constituted using two ultrasonic transducers of different frequency, two ultrasonic transducers are connected simultaneously by coaxial cable, two ultrasonic transducer one be low frequency piezoelectric supersonic wave transducer, one be high frequency piezo ultrasonic transducer, with obtain intravascular ultrasound echo-wave imaging harmony radiation force pulses imaging；The low frequency piezoelectric supersonic wave transducer is used to send high sound intensity radiation force pulses and generates deformational displacement in vascular tissue, and high frequency piezo ultrasonic transducer is for detecting micro-strain displacement and carrying out echo-wave imaging.The present invention can obtain acoustic radiation force Pulse Imageing and ultrasound image simultaneously, and in addition the present invention is using dual transducers but without increasing outer dimension, and ultrasonic endoscopic catheter tail equally only needs a rotation to withdraw device in the blood vessels.
Description
Technical field
The present invention relates to the field of medical instrument technology, radiate more particularly to a kind of machinery rotating type double frequency intravascular ultrasound
Power elastic imaging probe.
Background technique
Coronary heart disease is one of principal disease of human death, and the direct cause of disease is that vulnerable plaque ruptures to form thrombus, is caused
Lumen of vessels blocking and myocardial ischemia.Vulnerable plaque in EARLY RECOGNITION coronary artery facilitates patient and carries out pharmaceutical intervention treatment
Prevent coronary heart disease, or reduces the death rate of coronary heart disease by coronary revascularization.
Intravascular ultrasound imaging (IVUS) technology is the most frequently used physiological compositions composition and form knot to detect coronary plaques
The imaging means of structure information, referred to as new " goldstandard " of diagnosis of coronary heart disease.It can obtain the complete of blood vessel by strength signal
Whole three-decker information, and qualitatively to judge that the physiological compositions of patch form by echo signal strength information.In the blood vessels
Intravascular ultrasound Virtual Organization imaging (IVUS-VH) technology that further developed on the basis of ultrasonic imaging, with quantitative
Frequency spectrum parameter and Mathematical Statistics Analysis rebuild the organization chart picture of real-time patch, improve to patch structure and structural constituent judgement
Accuracy.
Although intravascular ultrasound imaging and intravascular ultrasound Virtual Organization imaging technique are clinically widely applied,
It is that this current two technologies are still unable to accurate judgement for the fibrous cap and some lipid core of vulnerable plaque.In addition, intravascular
Ultrasonic imaging and intravascular ultrasound Virtual Organization imaging technique cannot directly obtain the Mechanics of Machinery characteristic of patch each section, thus
Significantly limit its accuracy for diagnosing vulnerable plaque.
Acoustic radiation force Pulse Imageing technology can provide the Mechanics of Machinery characteristic information of intravascular tissue, promote diagnosis rapid wear
The accuracy of patch.The technology has been applied to the arterial vascular vulnerable plaque in the surface layers such as in-vitro diagnosis arteria carotis, but still lacks
The acoustic radiation force Pulse Imageing detection device of intervention diagnosis Plaque Vulnerability in Coronary Artery.
It is contemplated that the miniature intravascular ultrasound radiant force being integrated is imaged in intravascular ultrasound imaging harmony radiation force pulses
Pulse Imageing double frequency rotating detector, while being better than and keeping the image quality of intravascular ultrasound imaging, in conjunction with acoustic radiation force
Pulse Imageing information diagnoses vulnerable plaque.Its timeliness for diagnosing Plaque Vulnerability in Coronary Artery will be substantially better than with accuracy
Extracorporeal blood vessel plaque detection and intravascular ultrasound imaging software identify patch mode, and being expected to, which becomes coronary artery, checks new " gold mark
It is quasi- ".
Summary of the invention
In view of the technical drawbacks of the prior art, it is an object of the present invention to provide a kind of intravascular ultrasound imagings to examine
The disconnected machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe used, available intravascular ultrasound echo-wave imaging
The imaging of harmony radiation force pulses.
The technical solution adopted to achieve the purpose of the present invention is:
A kind of machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe, using two ultrasounds of different frequency
Energy converter constitutes the double-deck double frequency piezoelectric ultrasonic transducer architecture, passes through coaxial cable while connecting two ultrasonic transducers, and two
A ultrasonic transducer one be low frequency piezoelectric supersonic wave transducer, one be high frequency piezo ultrasonic transducer, to obtain blood vessel
Interior ultrasonic echo imaging harmony radiation force pulses imaging；The low frequency piezoelectric supersonic wave transducer is used to send high sound intensity radiation
Power pulse generates deformational displacement in vascular tissue, high frequency piezo ultrasonic transducer for detect micro-strain displacement and into
Row echo-wave imaging.
Further, the low frequency piezoelectric supersonic wave transducer and high frequency piezo ultrasonic transducer include matching layer and
Piezoelectric layer.
Wherein, the matching layer of each low frequency piezoelectric supersonic wave transducer and high frequency piezo ultrasonic transducer is one layer
Or multilayer.
Preferably, the material of the piezoelectric layer is piezoelectric ceramics, piezoelectric monocrystal, piezo-electricity composite material or other piezoresistive materials
Material.
Further, there are single layer or multilayer acoustics and thermal insulation layer between two ultrasonic transducers, wherein according to
Single layer acoustics and thermal insulation layer can choose low acoustic impedance, low-shrinkage, low thermal conductivity, high-fire resistance material temperature, thickness
It is 0.1-0.35 times of high frequency ultrasound wavelength in the material.Preferably, the centre frequency of the low frequency piezoelectric supersonic wave transducer
Range is 3-16MHz, and the central frequency range of high frequency piezo ultrasonic transducer is 30-80MHz.
Further, the double-deck double frequency piezoelectric ultrasonic transducer architecture that two ultrasonic transducers are formed is arranged in
In the shell of hollow-cylindrical structure.
Preferably, the housing diameter range is 0.5 millimeter -2 millimeters.
Wherein, the coaxial cable is single or two coaxial cables.
Compared with prior art, the beneficial effects of the present invention are:
Machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe of the invention, is able to achieve and makees intravascular ultrasound
Echo-wave imaging and the imaging of intravascular ultrasound radiation force pulses, can obtain tested tissue pattern, structurally and mechanically mechanics spy simultaneously
Property information, provides technical guarantee for the timely, quick of Plaque Vulnerability in Coronary Artery, Accurate Diagnosis.
In addition, the present invention is using dual transducers but without increasing outer dimension, and ultrasonic endoscopic conduit in the blood vessels
Tail portion equally only needs a rotation to withdraw device.
Detailed description of the invention
Fig. 1 is a kind of machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe of embodiment of the invention
General structure schematic diagram；
Fig. 2 is the piezo ultrasound transducers of machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe in Fig. 1
Structural schematic diagram.
Fig. 3 is the working principle block diagram of machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe in Fig. 1.
Specific embodiment
The present invention is described in further detail below in conjunction with the drawings and specific embodiments.It should be appreciated that described herein
Specific embodiment be only used to explain the present invention, be not intended to limit the present invention.
As shown in Figure 1, machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe 1 of the invention is (hereinafter referred to as
" ultrasound imaging probe "), it is the front end portion of intravascular ultrasound endoscopic catheters, there is shell 11, double frequency piezoelectric supersonic to sense
Device 2 and pillar 3.Outer Sales 11 is copper or the hollow cylindrical structure of other metal materials, there is an opening to place double frequency piezoelectricity super
Sonic transducer 2.Specifically, the double frequency piezo ultrasound transducers 2 are by high frequency sensors 2a and low-frequency sensor 2b with stacked
Double-layer structure composition, is fixed in shell 11 using bio-compatible glue.
Wherein, pillar 3 uses sound transparent material, plays the role of receiving and protection ultrasound imaging probe, does not interfere super
Acoustic imaging probe work.Specifically, entire ultrasound imaging probe is located in pillar 3, and when work, ultrasound imaging probe is by host computer
Control motor, which is rotated and withdrawn, completes mechanical scanning, and pillar 3 remains stationary.
Fig. 2 is the structural schematic diagram of double frequency piezo ultrasound transducers 2 in Fig. 1.Two ultrasonic transducers are the stacked double-deck knot
Structure, including high frequency matching layer 21, high frequency piezo layer 22, low frequency matching layer 23,25 and of low frequency piezoelectric layer 24, acoustics and thermal insulation layer
Back sheet 26.Wherein, the back sheet 26 may exist or be not present, and the high frequency matching layer 21 is placed in high frequency piezo layer
22,23 top of low frequency matching layer, the high frequency piezo layer 22, low frequency matching layer 23 are located on the same floor on face, the low frequency piezoelectricity
Layer 24 passes through acoustics with high frequency piezo layer 22, the low frequency matching layer 23 being located on the same floor on face and thermal insulation layer 25 separates, wherein
The material of piezoelectric layer is piezoelectric ceramics, piezoelectric monocrystal, piezo-electricity composite material or other piezoelectric materials.
In the present invention, high frequency matching layer 22, low frequency matching layer 23, acoustics and thermal insulation layer 25 quantity can be respectively one
Layer or multilayer.Structure shown in Fig. 2 is the case where high frequency matching layer 22, low frequency matching layer 23 and separation layer 25 are respectively one layer.
Wherein according to single layer acoustics and thermal insulation layer 25, can choose low acoustic impedance, low-shrinkage, low thermal conductivity,
High-fire resistance material temperature, with a thickness of 0.1-0.35 times of high frequency ultrasound wavelength in the material.
Fig. 3 is the working principle block diagram of the ultrasound imaging probe in Fig. 1.
The mechanical scanning popped one's head in the present invention using PC control motor；Host computer passes through control FPGA simultaneously
(Field-Programmable GateAray, i.e. field programmable gate array) is carried out at transmitting-receiving and the signal/image of signal
Reason.
Specifically, carrying out motor control by host computer, drives the rotation of ultrasound imaging probe and withdraw and complete mechanical scanning；
Excitation pulse signal (analogue stimulus signal) is generated by FPGA control high-voltage pulse generator, the voltage of the signal is enough to drive double
Frequency piezo ultrasound transducers 2 work and obtain ideal echo amplitude signal, and amplified signal (should by transmitting/receiving control switch
Module receives signal conditioning circuit for preventing transmitting signal from entering), it is sent to double frequency piezo ultrasound transducers of the invention
2；Received echo-signal through transmitting/receiving control switch and High Speed Analog front end (amplification, filtering, analog-to-digital conversion) reach FPGA into
Line number signal processing and image procossing, treated signal pass through data transmission interface (such as USB (Universal
Serial Bus, universal serial bus), PCIE (Peripheral Component Interconnect Express, high speed
Serial computer expansion bus standard) etc.), it uploads to host computer and carries out being imaged/being imaged display, while being deposited in memory
Storage.
The above is only a preferred embodiment of the present invention, it is noted that for the common skill of the art
For art personnel, various improvements and modifications may be made without departing from the principle of the present invention, these improvements and modifications
Also it should be regarded as protection scope of the present invention.
Claims (9)
1. a kind of machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe, it is characterised in that, using different frequency
Two ultrasonic transducers constitute the double-deck double frequency piezoelectric ultrasonic transducer architecture, pass through coaxial cable and connect two ultrasounds simultaneously
Energy converter, two ultrasonic transducer one be low frequency piezoelectric supersonic wave transducer, one be high frequency piezo ultrasonic transducer, with
Obtain the imaging of intravascular ultrasound echo-wave imaging harmony radiation force pulses；The low frequency piezoelectric supersonic wave transducer is used to send high-strength
Degree acoustic radiation force pulse generates deformational displacement in vascular tissue, and high frequency piezo ultrasonic transducer is for detecting micro-strain position
Shifting amount and progress echo-wave imaging.
2. machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe according to claim 1, it is characterised in that,
The low frequency piezoelectric supersonic wave transducer and high frequency piezo ultrasonic transducer include matching layer and piezoelectric layer.
3. machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe according to claim 2, it is characterised in that,
The matching layer of each low frequency piezoelectric supersonic wave transducer and high frequency piezo ultrasonic transducer is one or more layers.
4. machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe according to claim 1, it is characterised in that,
The material of the piezoelectric layer is piezoelectric ceramics, piezoelectric monocrystal, piezo-electricity composite material or other piezoelectric materials.
5. machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe according to claim 1, it is characterised in that,
There are single layer or multilayer acoustics and thermal insulation layer between two ultrasonic transducers, wherein according to single layer acoustics and being thermally isolated
Layer selects low acoustic impedance, low-shrinkage, low thermal conductivity, high-fire resistance material temperature, with a thickness of high-frequency ultrasonic in the material
Long 0.1-0.35 times.
6. machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe according to claim 1, it is characterised in that,
The central frequency range of the low frequency piezoelectric supersonic wave transducer is 3-16MHz, the center frequency of high frequency piezo ultrasonic transducer
Rate range is 30-80MHz.
7. machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe according to claim 1, it is characterised in that,
The outer of hollow cylindrical structure is arranged in the double-deck double frequency piezoelectric ultrasonic transducer architecture that two ultrasonic transducers are formed
In shell.
8. machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe according to claim 7, it is characterised in that,
The housing diameter range is 0.5 millimeter -2 millimeters.
9. machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe according to claim 1, it is characterised in that,
The coaxial cable is single or two coaxial cables.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910376841.5A CN110141268A (en) | 2019-05-07 | 2019-05-07 | A kind of machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe |
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| CN201910376841.5A CN110141268A (en) | 2019-05-07 | 2019-05-07 | A kind of machinery rotating type double frequency intravascular ultrasound radiant force elastic imaging probe |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110575627A (en) * | 2019-09-24 | 2019-12-17 | 黄晶 | Physical mapping device for rapidly acquiring target nerve treatment energy delivery site |
| CN113017780A (en) * | 2021-03-02 | 2021-06-25 | 哈尔滨医科大学 | Catheter system integrating ultrasonic imaging and rotational atherectomy of plaque in cavity |
| CN113367730A (en) * | 2021-06-18 | 2021-09-10 | 苏州圣泽医疗科技有限公司 | Method and device for simultaneously measuring blood flow parameters by double-frequency ultrasonic Doppler |
| CN113633316A (en) * | 2021-10-15 | 2021-11-12 | 深圳瀚维智能医疗科技有限公司 | Ultrasonic scanning method, apparatus and computer-readable storage medium |
| CN113907795A (en) * | 2021-11-03 | 2022-01-11 | 天津大学 | Transceiving system applied to intravascular ultrasonic imaging |
| WO2023097781A1 (en) * | 2021-11-30 | 2023-06-08 | 中国科学院深圳先进技术研究院 | Dual-frequency intravascular ultrasonic transducer and method and device used to calculate young modulus of blood vessel wall |
| WO2023097784A1 (en) * | 2021-11-30 | 2023-06-08 | 深圳先进技术研究院 | Dual-frequency endoscopic catheter and imaging device |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110575627A (en) * | 2019-09-24 | 2019-12-17 | 黄晶 | Physical mapping device for rapidly acquiring target nerve treatment energy delivery site |
| CN113017780A (en) * | 2021-03-02 | 2021-06-25 | 哈尔滨医科大学 | Catheter system integrating ultrasonic imaging and rotational atherectomy of plaque in cavity |
| CN113017780B (en) * | 2021-03-02 | 2022-03-08 | 哈尔滨医科大学 | Catheter system integrating ultrasonic imaging and rotational atherectomy of plaque in cavity |
| CN113367730A (en) * | 2021-06-18 | 2021-09-10 | 苏州圣泽医疗科技有限公司 | Method and device for simultaneously measuring blood flow parameters by double-frequency ultrasonic Doppler |
| CN113633316A (en) * | 2021-10-15 | 2021-11-12 | 深圳瀚维智能医疗科技有限公司 | Ultrasonic scanning method, apparatus and computer-readable storage medium |
| CN113907795A (en) * | 2021-11-03 | 2022-01-11 | 天津大学 | Transceiving system applied to intravascular ultrasonic imaging |
| CN113907795B (en) * | 2021-11-03 | 2024-03-29 | 天津大学 | Transmit-receive system applied to intravascular ultrasound imaging |
| WO2023097781A1 (en) * | 2021-11-30 | 2023-06-08 | 中国科学院深圳先进技术研究院 | Dual-frequency intravascular ultrasonic transducer and method and device used to calculate young modulus of blood vessel wall |
| WO2023097784A1 (en) * | 2021-11-30 | 2023-06-08 | 深圳先进技术研究院 | Dual-frequency endoscopic catheter and imaging device |
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