CN110128445B - P-chlorophenyl substituted chromone structure-containing spiro [ indazole-isoxazole ] derivative, and preparation method and application thereof - Google Patents
P-chlorophenyl substituted chromone structure-containing spiro [ indazole-isoxazole ] derivative, and preparation method and application thereof Download PDFInfo
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- CN110128445B CN110128445B CN201910530410.XA CN201910530410A CN110128445B CN 110128445 B CN110128445 B CN 110128445B CN 201910530410 A CN201910530410 A CN 201910530410A CN 110128445 B CN110128445 B CN 110128445B
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- indazole
- isoxazole
- dihydro
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- benzopyran
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
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CN201910530410.XA CN110128445B (en) | 2019-06-19 | 2019-06-19 | P-chlorophenyl substituted chromone structure-containing spiro [ indazole-isoxazole ] derivative, and preparation method and application thereof |
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CN201910530410.XA CN110128445B (en) | 2019-06-19 | 2019-06-19 | P-chlorophenyl substituted chromone structure-containing spiro [ indazole-isoxazole ] derivative, and preparation method and application thereof |
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CN110128445A CN110128445A (en) | 2019-08-16 |
CN110128445B true CN110128445B (en) | 2020-12-08 |
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CN103554135B (en) * | 2013-11-15 | 2016-01-20 | 绍兴文理学院 | A kind of containing chromone structure isoxazole norcantharidin derivative and preparation method thereof and application |
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Effective date of registration: 20211118 Address after: 250000 1422, building n, Hengda City, No. 58, Gongye North Road, Licheng District, Jinan City, Shandong Province Patentee after: Jinan Weiyang Technology Co.,Ltd. Address before: 312000 No. 508 West Ring Road, Zhejiang, Shaoxing Patentee before: SHAOXING University |
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Effective date of registration: 20211214 Address after: 450000 room 2625, second floor, administrative service center, South Yingbin Road, HANGGANG District, Zhengzhou City, Henan Province Patentee after: HENAN METAB BIOPHARMA Co.,Ltd. Address before: 250000 1422, building n, Hengda City, No. 58, Gongye North Road, Licheng District, Jinan City, Shandong Province Patentee before: Jinan Weiyang Technology Co.,Ltd. |