CN1100929A - Gas-forming capsule for gastrointestinal double contrast radiography - Google Patents

Gas-forming capsule for gastrointestinal double contrast radiography Download PDF

Info

Publication number
CN1100929A
CN1100929A CN 93109178 CN93109178A CN1100929A CN 1100929 A CN1100929 A CN 1100929A CN 93109178 CN93109178 CN 93109178 CN 93109178 A CN93109178 A CN 93109178A CN 1100929 A CN1100929 A CN 1100929A
Authority
CN
China
Prior art keywords
capsule
gas
double contrast
gastrointestinal
aerogenesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 93109178
Other languages
Chinese (zh)
Inventor
吕新胜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN 93109178 priority Critical patent/CN1100929A/en
Publication of CN1100929A publication Critical patent/CN1100929A/en
Pending legal-status Critical Current

Links

Images

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention relates to a gas-forming capsule for gastrointestinal double contrast radiography, belonging to a change of dosage form of gas-forming agent for X-ray gastrointestinal double contrast radiography diagnosis. Said capsule is made of gelatin, and can be disintegrated after 3 min. in endogastric acid environment, and can release the drugs contained in it. The drugs contained in the capsule are citric acid + sodium bicarbonate. After the capsule is disintegrated, the above-mentioned drugs are reacted, and CO2 gas is released.

Description

Gas-forming capsule for gastrointestinal double contrast radiography
The present invention relates to a kind of 100% gas generating agent at gastric generation gas, especially effect is obvious when low-strain air-barium imaging.
At present, Chang Yong double contrast radiograph gas generating agent is two kinds in tablet and a powder; Aerogenesis sheet or gas producing powder be put in the oral cavity take after mixing it with water, produce gas, but in the process of taking because the dosage form factor makes gas producing powder about 30% aerogenesis in oral cavity and esophagus, even 100% in the oral cavity aerogenesis; Cause gastric gas very little, do not reach the purpose that flattens coat of the stomach, make the double contrast radiograph effect relatively poor, same, the aerogenesis sheet is general oral more than 20, not only contain more additive in it, produce pseudo-shadow at gastric, and Chang Yin makes moist, gas discharges in advance, in gastric gas production deficiency, influence the effect of double contrast radiograph.
The purpose of this invention is to provide a kind of gas generating agent, it not only can provide the gas of capacity at gastric, and taking convenience, and consumption is less.
The object of the present invention is achieved like this: make the capsule that can partly insert mutually with gelatin, medicated powder sodium bicarbonate and citric acid that aerogenesis is used are sealed in the capsule, just make its protection against the tide on the encapsulated plastic plate at ordinary times; In use can take the 4-6 grain as required.Can carry out simultaneously for loose dose with the intramuscular injection smooth muscle when taking, taking the back greatly can be at the generation gas of gastric 100% about 8-10 minute; The smooth muscle of intramuscular injection is simultaneously also had an effect for loose dose, and gelatin is made capsule disintegrate rapidly in 2 minutes in the gastric sour environment, discharges wherein sodium bicarbonate and citric acid; Meet waterishlogging and give birth to reaction, discharge 100% carbon dioxide at gastric, being created in gas can show area gastrica and stomach ditch with the barium agent under the loose situation of body of stomach smooth muscle.
Owing to adopted capsule formulation, make its taking convenience, people's pars oralis pharyngis is stimulated disappear, and can 100% produce gas at gastric, reach the purpose of double contrast radiograph.
Fig. 1, Fig. 2 and shown in Figure 3 in, be respectively separation graph, positive bitmap, perspective view; Capsule shells is the standard type capsule shells, several microns approximately of disgraces, and wherein a semidiameter is smaller than second half, and can be inserted in about 3mm mutually; Aerogenesis medicated powder is loaded in the capsule, and sealing.

Claims (3)

1, a kind of gastrointestinal remakes the shadow Aerogenic capsule again, and aerogenesis medicated powder is sealed in the capsule, it is characterized by: the gelatine capsule that two parts of gas generant composition in accordance pruinescence are inserted in seals, and in the process of swallowing, does not discharge gas in oral cavity and esophagus.
2, according to claim 1, it is characterized by: pack in the Aerogenic capsule sodium bicarbonate and citric acid, and sealing, capsule disintegrate in the gastric sour environment that gelatin is made is very fast, can 100% in 10 minutes discharge aerogenesis medicated powder in it, and produce gas, its equation is as follows:
Figure 931091780_IMG1
3, according to claim 1, it is characterized by: the capsule sealing is loaded on moulding in the plate of damp proof insulation.
CN 93109178 1993-07-18 1993-07-18 Gas-forming capsule for gastrointestinal double contrast radiography Pending CN1100929A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 93109178 CN1100929A (en) 1993-07-18 1993-07-18 Gas-forming capsule for gastrointestinal double contrast radiography

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 93109178 CN1100929A (en) 1993-07-18 1993-07-18 Gas-forming capsule for gastrointestinal double contrast radiography

Publications (1)

Publication Number Publication Date
CN1100929A true CN1100929A (en) 1995-04-05

Family

ID=4987512

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 93109178 Pending CN1100929A (en) 1993-07-18 1993-07-18 Gas-forming capsule for gastrointestinal double contrast radiography

Country Status (1)

Country Link
CN (1) CN1100929A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105723099A (en) * 2013-11-06 2016-06-29 卡特彼勒Sarl Hydraulic pressure circuit and working machine
CN106362169A (en) * 2016-08-02 2017-02-01 欧阳林 Capsule-like gas contrast agent for gastrointestinal CT and application method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105723099A (en) * 2013-11-06 2016-06-29 卡特彼勒Sarl Hydraulic pressure circuit and working machine
CN106362169A (en) * 2016-08-02 2017-02-01 欧阳林 Capsule-like gas contrast agent for gastrointestinal CT and application method thereof
CN106362169B (en) * 2016-08-02 2019-11-19 中国人民解放军第一七五医院 A kind of stomach and intestine CT capsule-type gasgraphy agent and its application method

Similar Documents

Publication Publication Date Title
CA2341024A1 (en) Non-gelatin substitutes for oral delivery capsules, their composition and process of manufacture
AU727753B2 (en) Expandable gastro-retentive therapeutic system with controlled active substance release in the gastro-intestinal tract
US4167558A (en) Novel sustained release tablet formulations
US4140755A (en) Sustained release tablet formulations
JP3045388B2 (en) Agents for ingestion, production and use
JPS6322032A (en) Gellatin-enclosed slow release composition and manufacture
ES435500A1 (en) Solid therapeutic preparation remaining in stomach
JPH02212417A (en) Capsule of soft gelatine masticatory and eatable
HUT74878A (en) Stabilized composition for oral administration of peptides
WO1993000073A1 (en) Methods for making and administering a blinded oral dosage form and blinded oral dosage form therefor
CA2286079A1 (en) Cefadroxil monohydrate tablet formulation
CN1100929A (en) Gas-forming capsule for gastrointestinal double contrast radiography
AU3091997A (en) Composition for producing a long-lasting satiation effect
ES2107437T3 (en) PRODUCT FOR ORAL INGESTION.
US20140099360A1 (en) Gas Storage Vessel, Hydrogen-Charging Method, and Hydrogen-Charging Apparatus
CN217311192U (en) Sodium chloride filled capsule
KR101063077B1 (en) Hydrogen storage container, hydrogen sealing method, and hydrogen filling device
CN215350810U (en) Zinc gluconate capsule
CN2744341Y (en) Air generation capsule for air-barium double contrast radiography of small intestine
Mujoriya et al. A Overview on Study of Floating Drug Delivery Systems
MXPA04004035A (en) Methods and dosage forms for improving the bioavailability of therapeutic agents.
Rao et al. A CONCISE REVIEW ON FLOATING DRUG DELIVERY SYSTEM
US20200155466A1 (en) Oral Medicine Delivery Capsule
Katiyar A Review Report on Important Approches of Floating Drug Delivery System
AU2008255254B2 (en) A pharmaceutical tablet system that floats on gastric fluid for multipulse release of active substance and respective processes of producing same and a cup-shaped envelope of same

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication