CN110075428A

CN110075428A - A kind of beam examines, measurement method and device

Info

Publication number: CN110075428A
Application number: CN201910547282.XA
Authority: CN
Inventors: 杨宏成
Original assignee: Shanghai United Imaging Healthcare Co Ltd
Current assignee: Shanghai United Imaging Healthcare Co Ltd
Priority date: 2018-09-12
Filing date: 2019-06-24
Publication date: 2019-08-02
Anticipated expiration: 2039-06-24
Also published as: CN110075428B; US20200078605A1; US11077322B2

Abstract

The present invention provides a kind of beam methods of inspection.The beam method of inspection is suitable for examining the beam of radiation device, the radiation device includes at least radiation source, collimator and the imaging device being oppositely arranged with the radiation source, the radiation source is for generating the beam, the collimator is used to limit beam to the beam, which comprises based on the imaging device at least one source image determine away from an at least image for acquisition the beam beam axis and the collimator rotary shaft projected on the imaging device between at least one offset distance；And be compared at least one described offset distance with preset value, determine at least one described offset distance whether within preset value.The beam method of inspection of the invention can quickly and accurately test to beam.

Description

A kind of beam examines, measurement method and device

Prioity claim

This application claims submit on September 12nd, 2018 application No. is the preferential of 201811063410.5 China's application Power, the content of above-mentioned application are contained in this by reference.

Technical field

The invention mainly relates to the calibration of radiation device more particularly to beam inspections, measurement method and device.

Background technique

As a kind of conventional means for the treatment of malignant tumour, radiotherapy (radiation therapy) is to utilize radiation The energy that high energy beam that therapeutic equipment is launched generates destroys the chromosome in tumour cell, so that the tumour cell is stopped life It is long.Certainly, it if the irradiation for the high energy beam that normal cell is launched by radiotherapy equipment, can equally be killed.Therefore, have The high energy beam that necessity launches radiotherapy equipment only irradiates tumor region as much as possible.

The treatment head of existing radiotherapy equipment is usually provided with the collimator for beam shaping, so that outgoing is penetrated Beam is consistent with the aperture for the treatment of plan.In general, collimator can be rotated around a rotary shaft, and require the beam axis of beam It is consistent with the rotary shaft of collimator.This just needs to be adjusted radiotherapy equipment, calibrate and verify, to guarantee penetrating for beam Beam axis is consistent with the rotary shaft of collimator.However, the existing method for being adjusted, calibrating and verifying to radiotherapy equipment is logical Often relatively slow, inaccuracy, the judgement for needing additional hardware (such as water tank) and/or the people that needs to rely on.

Summary of the invention

The technical problem to be solved in the present invention is to provide a kind of inspection of beam, measurement method and devices, can be quick, quasi- It really tests, measure to beam.

In order to solve the above technical problems, an aspect of of the present present invention provides a kind of beam method of inspection, it is suitable for examining radiation The beam of equipment, the radiation device include at least radiation source, collimator and the imaging device being oppositely arranged with the radiation source, The radiation source is used to limit beam to the beam for generating the beam, the collimator, which comprises based on described Imaging device at least one source image away from at least image of acquisition determine the beam beam axis and the collimator Rotary shaft projected on the imaging device between at least one offset distance；And based at least one described offset distance And preset value, determine the beam axis relative to the rotary shaft deviation whether within preset value.

In some embodiments, when the beam axis relative to the rotary shaft deviation when other than preset value, adjustment The position of component relevant to the deviation in the radiation device；Otherwise, to related to the deviation in the radiation device Component do not adjust.

In some embodiments, at least one described source image away from for a source image away from.

In some embodiments, based on the imaging device at least one source image away from at least image obtained respectively The rotary shaft of the beam axis and the collimator that determine the beam projected on the imaging device between at least one partially Moving distance includes: in each source image away from place: based on the imaging device at least first image of the source image away from acquisition Determine the rotary shaft position that the rotary shaft projects on the imaging device；Based on the imaging device in the source image away from obtaining At least second image taken determines the Beam axis position that the beam axis projects on the imaging device；And according to institute It states rotary shaft position and the Beam axis position calculates the offset distance.

In some embodiments, the first image obtains in the following way: rotate the collimator to different angle, The image under different angle is acquired as the first image by the imaging device；And/or second image is to pass through The projected image of the correction model body of the imaging device acquisition.

An aspect of of the present present invention provides a kind of beam checking system, suitable for examining the beam of radiation device, the radiation Equipment includes at least radiation source, collimator and the imaging device being oppositely arranged with the radiation source, and the radiation source is for generating The beam, the collimator are used to limit beam to the beam, the system comprises: determining module, for being based on the imaging Device determines the beam axis of the beam and the rotation of the collimator away from an at least image for acquisition at least one source image Axis projected on the imaging device between at least one offset distance；And judgment module, for based on described at least one A offset distance and preset value, determine the beam axis relative to the rotary shaft deviation whether within preset value.

In some embodiments, the system also includes: adjustment module, for when the beam axis relative to the rotation The deviation of axis adjusts the position of component relevant to the deviation in the radiation device when other than preset value；Otherwise, to institute Component relevant to the deviation in radiation device is stated not adjust.

In some embodiments, the determining module is also used in each source image away from place: based on the imaging device in institute It states source image and determines rotary shaft position that the rotary shaft projects on the imaging device away from least first image for acquisition； Determine that the beam axis is filled in the imaging away from least second image for acquisition in the source image based on the imaging device Set the Beam axis position of projection；And the offset distance is calculated according to the rotary shaft position and the Beam axis position.

In some embodiments, the first image obtains in the following way: rotate the collimator to different angle, The image under different angle is acquired as the first image by the imaging device；The first image is marking plate, tungsten The projected image of door and at least one of multi-diaphragm collimator；Second image is the straightening die acquired by the imaging device The projected image of body；Second image is the perspective view for the correction model body that the imaging device acquires under different rack angles Picture.

An aspect of of the present present invention provides a kind of calibration method of radiation device, which comprises utilizes the beam The method of inspection determines deviation of the beam axis relative to the rotary shaft；And the radiation device is adjusted according to the deviation In component relevant to the deviation position.

An aspect of of the present present invention provides a kind of beam measurement device, and described device includes: computer readable storage medium, For storing the instruction that can be executed by processor；Processor realizes the beam method of inspection for executing described instruction.

An aspect of of the present present invention provides a kind of computer readable storage medium, is stored thereon with computer instruction, wherein When computer instruction is executed by processor, the beam method of inspection is realized.

An aspect of of the present present invention provides a kind of beam measurement method, suitable for measuring the beam of radiation device, the radiation Equipment includes at least radiation source, collimator and the imaging device being oppositely arranged with the radiation source, and the radiation source is for generating The beam, the collimator are used to limit beam to the beam, which comprises based on the imaging device multiple and different Source image determines that the beam axis of the beam and the rotary shaft of the collimator are filled in the imaging away from multiple images obtained respectively Set multiple distances between projection；And according to the multiple different source images away from determining the beam axis with the multiple distance Deviation relative to the rotary shaft.

In some embodiments, it is determined in multiple and different source images away from multiple images obtained respectively based on the imaging device The rotary shaft of the beam axis of the beam and the collimator projected on the imaging device between multiple distances include: Each source image is away from place: determining the rotary shaft away from least first image for acquisition in the source image based on the imaging device The rotary shaft position projected on the imaging device；At least one based on the imaging device in the source image away from acquisition Two images determine the Beam axis position that the beam axis projects on the imaging device；And according to the rotary shaft position and The Beam axis position calculates the distance.

In some embodiments, the first image obtains in the following way: rotate the collimator to different angle, The image under different angle is acquired as the first image by the imaging device.

In some embodiments, the first image is the projection of at least one of marking plate, tungsten door and multi-diaphragm collimator Image.

In some embodiments, second image is the perspective view of the correction model body acquired by the imaging device Picture.

In some embodiments, second image is the correction model body that the imaging device acquires under different rack angles Projected image.

In some embodiments, the deviation includes: inclination angle of the beam axis relative to the rotary shaft；And/or Offset of the beam axis relative to the rotary shaft.

In some embodiments, the offset be between the beam axis and the rotary shaft project on target plane away from From.

In some embodiments, based on the multiple different source images away from the multiple distance, utilize geometrical relationship to determine The inclination angle and the offset.

In some embodiments, based on the multiple different source images away from the multiple distance, utilize geometrical relationship to determine Multiple inclination angle initial values and multiple offset initial values are fitted the inclination angle initial value and the offset initial value described in determining and incline Oblique angle and the offset.

An aspect of of the present present invention provides a kind of beam measurement method, suitable for measuring the beam of radiation device, the radiation Equipment includes at least radiation source, collimator and the imaging device being oppositely arranged with the radiation source, and the radiation source is for generating The beam, the collimator are used to limit beam to the beam, which comprises the imaging device is in the first source image away from obtaining Take at least first image；The imaging device the second source image away from obtain an at least the first image, described first Image is adapted to determine that the position that the rotary shaft of the collimator projects on the imaging device；The imaging device is described One source image is away from acquisition at least second image；The imaging device is at second source image at least one described second away from acquisition Image, second image are adapted to determine that the position that the beam axis of the beam projects on the imaging device；According to described First image and second image determine, the imaging device be located at first source image away from when, the beam axis with it is described The first distance that rotary shaft projects on the imaging device；It is determined according to the first image and second image, it is described Imaging device be located at second source image away from when, the beam axis and the rotary shaft projected on the imaging device second Distance；And according to the first distance, the second distance, first source image away from second source image away from described in determination Deviation of the beam axis relative to the rotary shaft.

In some embodiments, it is determined according to the first image and second image, the imaging device is located at institute State the first source image away from when, the first distance that the beam axis and the rotary shaft project on the imaging device includes: basis The imaging device first source image away from an at least the first image for acquisition determine the rotary shaft it is described at As the first rotary shaft position projected on device；According to the imaging device in an at least institute of first source image away from acquisition It states the second image and determines the first Beam axis position that the beam axis projects on the imaging device；And according to described first Rotary shaft position and first Beam axis position calculate the first distance.

In some embodiments, it is determined according to the first image and second image, the imaging device is located at institute State the second source image away from when, the second distance that the beam axis and the rotary shaft project on the imaging device includes: basis The imaging device second source image away from an at least the first image for acquisition determine the rotary shaft it is described at As the second rotary shaft position projected on device；Based on the imaging device in an at least institute of second source image away from acquisition It states the second image and determines the second Beam axis position that the beam axis projects on the imaging device；And according to described second Rotary shaft position and second Beam axis position calculate the second distance.

An aspect of of the present present invention provides a kind of method of inspection of radiation device, comprising: is surveyed using beam as described above Amount method determines deviation of the beam axis relative to the rotary shaft；And be compared the deviation with preset value, really Whether the fixed deviation is within preset value.

Another aspect of the invention provides a kind of calibration method of radiation device, comprising: utilizes beam as described above Measurement method determines deviation of the beam axis relative to the rotary shaft；And the radiation device is adjusted according to the deviation In component relevant to the deviation position.

An aspect of of the present present invention provides a kind of beam measurement device, comprising: computer readable storage medium, for storing The instruction that can be executed by processor；Processor realizes method as described above for executing described instruction.

An aspect of of the present present invention provides a kind of computer readable storage medium, is stored thereon with computer instruction, wherein When computer instruction is executed by processor, method as described above is realized.

Compared with prior art, the invention has the following advantages that

Beam measurement method of the invention, device be by analyze, handle the image of imaging device acquisition come it is further true Determine deviation of the beam axis relative to rotary shaft, in this process, needs not rely upon the judgement of people, measurement workflow is simple, drop Low measurement cost and time, and quickly and accurately beam can be measured.

Detailed description of the invention

Fig. 1 is the structure chart of the radiotherapy equipment of some embodiments of the invention.

Fig. 2 is the structure chart of the radiotherapy equipment treatment head of some embodiments of the invention.

Fig. 3 is the structure chart of the radiotherapy equipment beam measurement device of some embodiments of the invention.

Fig. 4 be some embodiments of the invention beam axis and rotary shaft a plane perspective view.

Fig. 5 is the flow diagram of the beam measurement method of some embodiments of the invention.

Fig. 6 is the flow diagram of the determination first distance of some embodiments of the invention.

Fig. 7 is the flow diagram of the determination second distance of some embodiments of the invention.

Fig. 8 is the flow diagram of the beam measurement method of some embodiments of the invention.

Fig. 9 is the flow diagram of the beam measurement method of some embodiments of the invention.

Figure 10 is the flow diagram of the method for inspection of the radiotherapy equipment of some embodiments of the invention.

Figure 11 is the flow diagram of the calibration method of the radiotherapy equipment of some embodiments of the invention.

Figure 12 is the flow diagram of the beam method of inspection of some embodiments of the invention.

Figure 13 is the flow diagram of at least one offset distance of the determination of some embodiments of the invention.

Figure 14 is the flow diagram of the calibration method of the radiotherapy equipment of some embodiments of the invention.

Figure 15 be some embodiments of the invention beam axis and rotary shaft a plane perspective view.

Figure 16 is a kind of module map of beam verifying attachment of some embodiments of the invention.

Specific embodiment

In order to illustrate more clearly of the technical solution of embodiments herein, will make below to required in embodiment description Attached drawing is briefly described.It should be evident that the accompanying drawings in the following description is only some examples or implementation of the application Example, for those of ordinary skill in the art, without creative efforts, can also be according to these attached drawings The application is applied to other similar scene.Unless being explained obviously or separately, identical label generation in figure from language environment The identical structure or operation of table.

As shown in the application and claims, unless context clearly prompts exceptional situation, " one ", "one", " one The words such as kind " and/or "the" not refer in particular to odd number, may also comprise plural number.It is, in general, that term " includes " only prompts to wrap with "comprising" Include clearly identify the step of and element, and these steps and element do not constitute one it is exclusive enumerate, method or apparatus The step of may also including other or element.

Although the application is made that various references to the certain module in system according to an embodiment of the present application, however, Any amount of disparate modules can be used and be operated in and be calculated on equipment and/or processor.The module is only illustrative , and disparate modules can be used in the different aspect of the system and method.

It should be understood that when unit or module be described as " connecting ", " coupling " other units, module or when block, It can refer to and be directly connected to or couple, perhaps be communicated with other units, module or block or there may be intermediate units, module Or block, unless context clearly indicates other way.Term as used herein "and/or" may include one or more related columns Any and all combinations of project out.

Flow chart used herein is used to illustrate operation performed by system according to an embodiment of the present application.It should Understand, before or operation below not necessarily accurately carry out in sequence.On the contrary, can be handled according to inverted order or simultaneously Various steps.Meanwhile or during other operations are added to these, or from these processes remove a certain step or number step operation.

The embodiment of the present invention description is suitable for beam measurement method, the method for inspection and the calibration method of radiation device. Wherein, radiation device includes at least radiation source, collimator and the imaging device being oppositely arranged with radiation source.Radiation source is for generating Beam, collimator are used to limit beam to the beam, and imaging device is for being imaged beam.Radiation device may include radiation Therapeutic equipment, DR (Digital Radiography) equipment, C-arm equipment etc..Hereafter mainly by taking radiotherapy equipment as an example into Row description, but it is not limitation of the present invention.

Fig. 1 is the structure chart of the radiotherapy equipment of some embodiments of the invention, refering to what is shown in Fig. 1, radiotherapy equipment 100 include fixed part 101 and rotating part 102, and rotating part 102 is mounted on fixed part 101, and rotating part 102 can To be rotated around central axis 106, radiotherapy is carried out to patient in different angle to realize.

The side of rotating part 102 is treatment head 103, and treatment head 103 can produce the beam of high level, in hospital bed Patient on 105 carries out radiotherapy.Beam may include the radiation of electronics, photon or any other type.For example, beam can Think X-ray (usually megavolt grade).For the radiotherapy equipment of homologous two-beam, treatment head 103 can also generate low-lying level X-ray (the usually megavolt grade of KV level or low energy), low-lying level X-ray can be used to patient is imaged, utilize The patient image arrived carries out image guided radiation therapy (Image Guided Radiation Therapy) to patient.

When being imaged by low-lying level X-ray, treatment head 103 can issue cone-beam X-ray, and rotating part 102 is another The imaging device 104 of side receives the X-ray across patient, forms the projected image (projection under the angle image).Imaging device 104 for example can be electronic portal image device (electronic portal imaging Devices, EPID).Treatment head 103 can form the projected image of multiple angles when different angle is irradiated.

Fig. 2 is the structure chart of the radiotherapy equipment treatment head of some embodiments of the invention.Refering to what is shown in Fig. 2, treatment head 103 may include the collimator 31 for beam shaping.Collimator 31 may include beam stop to 31a and beam stop pair 31b.Beam stop for example can be tungsten door (Jaw) or multi-diaphragm collimator (Multi- to 31b to 31a and/or beam stop Leaves Collimator, MLC).The beam that beam bombardment target (not shown) is formed can be passed through without being blocked and be penetrated Beam stops the opening that 31b is collectively formed in 31a and beam stop, or can pass through beam stop and hinder 31a and/or beam Gear is to 31b to which transmitted intensity is attenuated.Collimator 31 can be rotated around rotary shaft 30, so that treatment head 103 is capable of forming Various required beam shapes.

Treatment head 103 can also include auxiliary tray 32.Auxiliary tray 32 may be configured to accommodate or keep various attached Part, such as marking plate, wedge block etc..Marking plate for example can be graticle, the semi-transparent metals plate with central ring.Some In embodiment, auxiliary tray 32 can follow collimator 31 to rotate together around rotary shaft 30.That is, collimator 31 around During rotary shaft 30 rotates, positional relationship that auxiliary tray 32 and collimator 31 are kept fixed.

Radiotherapy equipment 100 further includes beam measurement device 107.Beam measurement device 107 can be according to imaging device 104 measure beam away from (source-imager-distance, SID) multiple images obtained in multiple and different source images (will be described in more detail below).In some embodiments, beam measurement device 107 can also control rotating part 102, treatment head 103, the running of at least one of imaging device 104 and hospital bed 105.For example, beam measurement device 107 can control rotating part 102 rotational time, rotation angle etc..In another example beam measurement device 107 can control the beam of the outgoing for the treatment of head 103 Shape, intensity etc..In another example beam measurement device 107 can control the opportunity etc. that imaging device 104 obtains image.For another example Beam measurement device 107 can control the motion profile of hospital bed 105.

Fig. 3 is the structure chart of the radiotherapy equipment beam measurement device of some embodiments of the invention.Refering to what is shown in Fig. 3, Beam measurement device 107 can be used to realize the ad hoc approach and device for implementing to disclose in some embodiments of the invention.This reality Apply specific device in example using functional block diagram illustrate one include display module hardware platform.In some embodiments, Beam measurement device 107 can realize the present invention by its hardware device, software program, firmware and their combination The specific implementation of embodiment.In some embodiments, beam measurement device 107 can be the computer of a general purpose, or One has the computer of specific purpose.In some embodiments, beam measurement device 107 can be mobile terminal, PC, Server, cloud computing platform etc..

As shown in figure 3, beam measurement device 107 may include internal communication bus 71, processor (processor) 72, Read-only memory (ROM) 73, random access memory (RAM) 74, communication port 75, input output assembly 76, hard disk 77 and User interface 78.The data communication of 107 inter-module of beam measurement device may be implemented in internal communication bus 71.Processor 72 can be with Judged and issued prompt.In some embodiments, processor 72 can be made of one or more processors.Communication port 75 may be implemented beam measurement device 107 and other component (not shown) for example: external equipment, image capture device, number According to carrying out data communication between library, external storage and image processing workstations etc..In some embodiments, beam measurement device 107 can send by communication port 75 from network and receive information and data.Input output assembly 76 supports beam measurement dress Set the input/output data stream between 107 and other component.As an example, input output assembly 76 may include below group Part it is one or more: mouse, trace ball, keyboard, touch control component, sound receiver etc..Beam may be implemented in user interface 78 Interaction and information exchange between measuring device 107 and user.Beam measurement device 107 can also include computer-readable storage Medium.Computer readable storage medium may include various forms of program storage units and data storage element, such as firmly Disk 77, read-only memory (ROM) 73 and random access memory (RAM) 74, can store computer disposal and/or communication uses Various data files and processor 72 performed by possible program instruction.

Fig. 4 be some embodiments of the invention beam axis and rotary shaft a plane perspective view.It is appreciated that figure The projection of beam axis shown by 4 and rotary shaft can be beam axis and rotary shaft XOZ plane shown in Fig. 1, be also possible to Projection in YOZ plane, or other any planes vertical with XOY plane.Coordinate origin O shown in figure 1 is in waiting Heart point, Z axis be from isocenter point towards rack angle be 0 degree when source point direction (or being direction straight up), Y-axis is edge For the central axis 106 of rotating part 102 towards the direction of radiotherapy equipment, X-axis is the direction perpendicular to YOZ plane, constitutes one Right-handed coordinate system.

Refering to what is shown in Fig. 4, the source point S for the treatment of head 103 is located on target plane TP in a plane, treatment head 103, which has, is penetrated Beam axis 40, collimator 31 have rotary shaft 30.Beam axis 40 has relative to rotary shaft 30 to be deviateed.Rotary shaft 30 and beam axis 40 Extended line cross at virtual point V.Available, beam axis 40 has inclined angle alpha, 40 phase of beam axis relative to rotary shaft 30 There is shifted by delta, such as the shifted by delta on target plane TP for rotary shaft 30_TP.Therefore, beam axis 40 is relative to rotary shaft 30 Deviation can at least be indicated by inclined angle alpha and/or shifted by delta.It can according to the geometrical relationship of beam axis 40 and rotary shaft 30 Know, learn the first source image away from d1, beam axis 40 and rotary shaft 30 in the first source image away from the first distance Δ at d1₁, the second source Image distance d2, beam axis 40 and rotary shaft 30 are in the second source image away from the second distance Δ at d2₂After can calculate 40 phase of beam axis Deviation for rotary shaft 30.The deviation may include inclination angle of the beam axis relative to the rotary shaft；And/or institute State offset of the beam axis relative to the rotary shaft.

In some embodiments, as shown in figure 15, beam measurement device 107 can according in the first source image away from d1 One distance, delta₁To determine beam axis 40 and rotary shaft 30 in the first source image away from departure degree at d1.For example, by first distance Δ₁With Preset value is compared, and determines first distance Δ₁Whether within preset value, so as to examine the departure degree of beam.When First distance Δ₁When not in values, it can determine that radiotherapy equipment 100 needs to adjust its associated components, such as Other position of components etc. in the position of accelerating tube, the position for adjusting target or adjustment treatment head are adjusted, beam axis 40 and rotation are made The relationship of axis 30 meets the requirements.The position for adjusting associated components can realize by controlling the movement of movable part, can also To be realized by artificial adjustment.Specifically, it is referred to a kind of beam method of inspection 700 of Figure 12.

Fig. 5 is the flow diagram of the beam measurement method of some embodiments of the invention.Beam measurement method 200 can be It is performed in beam measurement device 107.Beam measurement method 200 may include steps of:

Step 210: determining the beam axis and collimation of beam away from multiple images of acquisition in the first source image based on imaging device The rotary shaft of device projected on imaging device between first distance；

Step 220: based on imaging device the second source image away from multiple images of acquisition determine beam axis and rotary shaft at As the second distance on device between projection；And

Step 230: according to first distance, second distance, the first source image away from the second source image away from determine beam axis relative to The deviation of rotary shaft.

It in some embodiments, can be under different rack angles, in the first source image away from being obtained respectively with the second source image away from position Take deviation of multiple images with the beam axis under the different rack angles of determination relative to rotary shaft.

It should be noted that the operation order of beam measurement method 200 shown in fig. 5 is not intended to limit the present invention.Example Such as, step 210 and step 220 may be performed simultaneously.In another example step 220 can be executed prior to step 210.

Fig. 6 is the flow diagram of the determination first distance of some embodiments of the invention.Refering to what is shown in Fig. 6, step 210 can To include:

Step 211: based on imaging device the first source image away from least first image for acquisition determine rotary shaft at As the first rotary shaft position projected on device；

Step 212: based on imaging device the first source image away from least second image for acquisition determine beam axis at As the first Beam axis position projected on device；And

Step 213: first distance is calculated according to the first rotary shaft position and the first Beam axis position.

Similarly, the operation order of the process of determining first distance illustrated in fig. 6 is not intended to limit the present invention.Example Such as, step 211 and step 212 may be performed simultaneously.In another example step 212 can be executed prior to step 211.

In step 211, the first image can be any projection position that can determine rotary shaft 30 on imaging device 104 The image set.Such as can obtain the first image in the following way: rotary collimator 31 to different angle passes through imaging device Image under 104 acquisition different angles is as the first image.

In some embodiments, the first image may include the projected image of the marking plate of rotation, and marking plate follows collimation Device rotation.Specifically, the first image can obtain in the following manner: marking plate being inserted into auxiliary tray 32, is revolved Turn collimator 31, imaging device 104 is in the first source image away from the projected image for obtaining one or more marking plate at d1.It is some more In specific embodiment, treatment head 103 and imaging device 104 can be under the drives of rotating part 102, at different rack angles The projected image of the marking plate of rotation is obtained, to obtain the first image.It is appreciated that since the first image contains the mark of rotation The projected image for remembering plate, finds the rotation center of certain elements in projected image, that is, can determine that rotary shaft 30 is filled in imaging Set the first rotary shaft position projected on 104.Remember that the first rotary shaft position is (u1, v1).

In some embodiments, the first image may include the tungsten door (Jaw) and/or multi-diaphragm collimator (Multi- of rotation Leaf Collimator, MLC) projected image.That is, in this embodiment it is possible to without being inserted into marking plate, but First rotary shaft is directly determined to the projected image of 31b to 31a and/or beam stop using the beam stop in collimator 31 Position.Specifically, in rotary collimator 31, beam stop can follow collimator 31 to 31b to 31a and/or beam stop Rotation, imaging device 104 can the first source image away from d1 at acquisition one or more beam stop to 31a and/or beam stop To the projected image of 31b.Similarly, treatment head 103 and imaging device 104 can be under the drives of rotating part 102, in difference Rack angle obtain rotation tungsten door and/or multi-diaphragm collimator projected image, to obtain first image.It is appreciated that by The tungsten door of rotation and/or the projected image of multi-diaphragm collimator are contained in the first image, certain elements are found in projected image Rotation center, that is, can determine that the first rotary shaft position that rotary shaft 30 projects on imaging device 104.Remember the first rotary shaft Position is (u1, v1).

In step 212, the second image can be any projection position that can determine beam axis 40 on imaging device 104 The image set.

In some embodiments, the second image may include the projected image of correction model body.Correction model body can be BB mould Body.Specifically, the second image can obtain in the following manner: correction model body is set to its coordinate system and radiotherapy At the position that 100 coordinate system of equipment is overlapped, imaging device 104 is in the first source image away from the one or more correction model bodies of acquisition at d1 Projected image.In some more specific embodiments, it can use geometric correction method and determine beam axis 40 in imaging device 104 On projected position.Correction model body has one or more opaque markers, these markers are in die body coordinate system Three-dimensional position is known.After imaging device 104 gets the projected image of correction model body, these available markers exist Position in projected image.Three-dimensional position based on marker and its position on projection images, it can building projection square Battle array.Only as an example, for a rack angle, projection matrix corresponding with the rack angle can be by following formula come really It is fixed:

Wherein (x_i, y_i, z_i) indicate i-th of marker coordinate, (u_i, v_i) indicate i-th of marker in imaging device 104 On projection coordinate, i is greater than 1 integer, t_iIndicate weight factor.Only as an example, the weight factor t_iExist with X-ray Penetration length in die body is related.

The projection matrix can further indicate that are as follows:

Wherein P can indicate the projection matrix, from P₁₁To P₃₄Each of representation in components projection matrix component, Wherein (P₁₄,P₂₄) indicate projected position of the beam centre on imaging device 104.Therefore, it can use projection matrix to determine First Beam axis position of the beam axis 40 on imaging device 104.Remember imaging device 104 on the first Beam axis position be (u1 ', v1').In some embodiments, treatment head 103 and imaging device 104 can be under the drives of rotating part 102, different Rack angle obtains the second image, and is determined under at least partly rack angle using the second image obtained under different rack angles First Beam axis position.

In some embodiments, treatment head 103 and imaging device 104 can be under the drives of rotating part 102, in difference Rack angle obtain the second image.That is, the second image can be the school that imaging device 104 acquires under different rack angles The projected image of positive die body.In this embodiment, correction model body coordinate system can not be weighed with 100 coordinate system of radiotherapy equipment It closes, that is, there may be put deviation to correction model body.It is described to put deviation and refer to that correction model body coordinate system is set with radiotherapy The deviation of standby 100 coordinate systems.

It in some embodiments, can be in the case where putting deviation there are correction model body, using at different rack angles Multiple second images obtained determine the position of the first beam axis.Only as an example, the throwing of 100 coordinate system of radiotherapy equipment Shadow matrix can be determined by following formula:

P_IEC=P × T_trans (3)

Wherein, P_IECIt can indicate that the projection matrix of 100 coordinate system of radiotherapy equipment, P indicate the school as shown in formula (2) The projection matrix of positive die body coordinate system, T_transIndicate transition matrix.Further, it is possible to be based on 100 coordinate system of radiotherapy equipment Multiple projection matrix P_IECDetermine beam centre.

It only as an example, can be based on the projection of the corresponding correction model body coordinate system in multiple rack angles and multiple rack angle Matrix P determines the origin and radiotherapy equipment 100 of 100 coordinate system of radiotherapy equipment in correction model body coordinate system Deflection angle of the coordinate system relative to correction model body coordinate system.

It only as an example, can origin based on identified 100 coordinate system of radiotherapy equipment and the deflection Angle determines the transition matrix of 100 coordinate system of correction model body coordinate system and radiotherapy equipment.

Only as an example, transition matrix T_transIt can indicate are as follows:

In formula (4), (x₀, y₀, z₀) it can indicate the radiotherapy equipment in the correction model body coordinate system The origin of 100 coordinate systems.For along the X of 100 coordinate system of radiotherapy equipment_fThe first of axis is single Expression of the bit vector in correction model body coordinate system, whereinFirst unit vector is respectively indicated in school The just projection value of the X-axis, Y-axis and Z-direction of die body coordinate system.For along radiotherapy equipment 100 The Y of coordinate system_fExpression of second unit vector of axis in correction model body coordinate system, whereinIt respectively indicates Projection value of second unit vector in the X-axis of correction model body coordinate system, Y-axis and Z-direction.For Along the Z of 100 coordinate system of radiotherapy equipment_fExpression of the third unit vector of axis in correction model body coordinate system, whereinThe third unit vector is respectively indicated in the projection of the X-axis of correction model body coordinate system, Y-axis and Z-direction Value.T_transExpression is used for, for example, being converted to the information indicated with the correction model body coordinate system with the radiotherapy equipment The transition matrix for the information that 100 coordinate systems indicate.

More detailed contents about geometric correction method can be found in patent application CN201710640498.1, herein full text It introduces.

In step 213, the first distance Δ u in XOZ plane can be calculated₁=u1'-u1.Likewise it is possible to calculate First distance Δ v in YOZ plane₁=v1'-v1.

Fig. 7 is the flow diagram of the determination second distance of some embodiments of the invention.Refering to what is shown in Fig. 7, step 220 can To include:

Step 221: based on imaging device the second source image away from least first image for acquisition determine rotary shaft at As the second rotary shaft position projected on device；

Step 222: based on imaging device the second source image away from least second image for acquisition determine beam axis at As the second Beam axis position projected on device；And

Step 223: second distance is calculated according to the second rotary shaft position and the second Beam axis position.

Similarly, the operation order of the process of determining second distance illustrated in fig. 7 is not intended to limit the present invention.Example Such as, step 221 and step 222 may be performed simultaneously.In another example step 222 can be executed prior to step 221.

In step 221 the first image and determining second rotation can be obtained using with the same or similar mode of step 211 Rotating shaft position.Step 221 and step 211 the difference is that, the first image is in different source images away from acquisition, and really Fixed is projected position of rotary shaft of the different source images away from place on imaging device 104.Therefore, here no longer to step 221 Carry out expansion description.

Remember that the second rotary shaft position is (u2, v2).

It second can be penetrated using obtaining the second image with the same or similar mode of step 212 and determining in step 222 Beam shaft position.Step 222 and step 212 the difference is that, the second image is in different source images away from acquisition, and really Fixed is projected position of beam axis of the different source images away from place on imaging device 104.Therefore, here no longer to step 222 Carry out expansion description.

Remember that second Beam axis position is (u2 ', v2 ') on imaging device 104.

In step 223, the second distance Δ u in XOZ plane can be calculated₂=u2'-u2.Likewise it is possible to calculate Second distance Δ v in YOZ plane₂=v2'-v2.

In some embodiments, step 230 can be according to first distance Δ u₁, second distance Δ u₂, the first source image away from d1 and Second source image determines inclined angle alpha of the beam axis relative to rotary shaft in XOZ plane away from d2_XOZ, and/or according to first distance Δ v₁, second distance Δ v₂, the first source image away from d1 and the second source image determine that beam axis is relative to rotary shaft in YOZ plane away from d2 Inclined angle alpha_YOZ.Step 230 can also be according to inclined angle alpha_XOZAnd inclined angle alpha_YOZDetermine inclined angle alpha.In some embodiments In, inclined angle alpha can be determined according to geometrical relationship_XOZ, inclined angle alpha_YOZAnd inclined angle alpha.

Below by XOZ plane inclination angle and offset for be illustrated.In some embodiments, inclined angle alpha_XOZIt can To be calculate by the following formula to obtain:

In some embodiments, step 230 can be according to first distance Δ u₁, second distance Δ u₂, the first source image away from d1 and Second source image determines the shifted by delta in XOZ planar beam of radiation axis relative to rotary shaft away from d2_XOZ.It in some embodiments, can basis Geometrical relationship determines shifted by delta_XOZ.Specifically, shifted by delta_XOZIt can be calculate by the following formula to obtain:

Δ_XOZ=Δ d_XOZ·tan(α_XOZ),

Wherein, Δ d_XOZFor at a distance from imaginary intersection point to target plane of the XOZ Plane Rotation axis with beam axis.

In some embodiments, in the distance, delta d of the imaginary intersection point of XOZ Plane Rotation axis and beam axis to target plane_XOZIt is logical Following manner is crossed to be calculated:

In some embodiments, tan (α_XOZ) it is calculated in the following manner:

The calculating at inclination angle and offset in YOZ plane is similar with the inclination angle in XOZ plane and offset, only need to be upper State the first distance Δ u in formula₁Replace with first distance Δ v₁, second distance Δ u₂Replace with first distance Δ v₂.Cause This, not reinflated description herein.

First source image can measure to obtain in several ways away from d1 and/or the second source image away from d2.In some embodiments, First source image can be obtained away from d1 and/or the second source image away from d2 by way of laser ranging, to obtain accurate first source image Away from d1 and/or the second source image away from d2.

It should be noted that, although above-described embodiment be with by two source images away from upper beam axis at a distance from rotary shaft Determine deviation of the beam axis relative to rotary shaft, it is to be understood that, it can also by the source image of more away from upper beam axis With determine deviation of the beam axis relative to rotary shaft at a distance from rotary shaft.

For example, obtaining at least first image respectively in each source image away from place and determining rotary shaft on imaging device Projected position and at least second image determines projected position of the beam axis on imaging device, then obtain following relationship:

Wherein, Δ u_iIt is projected on imaging device away from place's beam axis and rotary shaft for i-th of source image in XOZ plane Between distance, d_iIt away from, i is positive integer for i-th of source image, and i=1,2,3 ... ... n, Δ d_XOZFor the rotary shaft in XOZ plane At a distance from the imaginary intersection point to target plane of beam axis.

(d₁+Δd_XOZ)tanα_XOZ=Δ u₁

(d₂+Δd_XOZ)tanα_XOZ=Δ u₂

(d_n+Δd_XOZ)tanα_XOZ=Δ u_n

It can be expressed as with matrix

Solve system of equation can obtain tan α_XOZWith Δ d_XOZ, and then acquire shifted by delta_XOZAnd inclined angle alpha_XOZ。

The calculating at inclination angle and offset in YOZ plane is similar with the inclination angle in XOZ plane and offset, herein no longer Expansion description.

Fig. 8 is the flow diagram of the beam measurement method of some embodiments of the invention.Refering to what is shown in Fig. 8, beam measures Method 300 can be performed in beam measurement device 107.Beam measurement method 300 may include steps of:

Step 310: determining the beam of beam away from multiple images obtained respectively in multiple and different source images based on imaging device The rotary shaft of axis and collimator projected on imaging device between multiple distances；

Step 320: according to multiple and different source images away from the deviation with the determining beam axis of multiple distances relative to rotary shaft.

In some embodiments, beam measurement method 300 can also be utilized through multiple source images away from determining multiple deviations Average value as deviate.The average value can be calculated by arithmetic average, weighted average etc..

It in some embodiments, can also be by more on imaging device 104 away from determining beam axis in multiple source images A projected position is fitted beam axis.In some embodiments, can also by multiple source images away from determining rotary shaft at Rotary shaft is fitted as multiple projected positions on device 104.It in some embodiments, can also be by the beam axis that fits Deviation of the beam axis relative to rotary shaft is determined with the rotary shaft fitted.

In some embodiments, can based on multiple and different source images away from multiple and different distances, utilize geometrical relationship determine Multiple inclination angle initial values and offset initial value are fitted determining inclination angle and offset to inclination angle initial value and offset initial value.

Fig. 9 is the flow diagram of the beam measurement method of some embodiments of the invention.Refering to what is shown in Fig. 9, beam measures Method 400 may include steps of:

Step 410: imaging device is in the first source image away from acquisition at least first image；

Step 420: imaging device is in the second source image away from acquisition at least first image；Wherein, the first image is suitable for true Determine the position that the rotary shaft of collimator projects on imaging device；

Step 430: imaging device is in the first source image away from acquisition at least second image；

Step 440: imaging device is in the second source image away from acquisition at least second image；Wherein, the second image is suitable for true Determine the position that the beam axis of beam projects on imaging device；

Step 450: determined according to the first image and the second image, imaging device be located at the first source image away from when, beam axis and Rotary shaft projected on imaging device between first distance；

Step 460: determined according to the first image and the second image, imaging device be located at the second source image away from when, beam axis and Rotary shaft projected on imaging device between second distance；And

Step 470: according to first distance, second distance, the first source image away from the second source image away from determine beam axis relative to The deviation of rotary shaft.

It should be noted that the operation order of beam measurement method 400 shown in Fig. 9 is not intended to limit the present invention.Example Such as, step 420 can be executed prior to step 410, and step 440 can be executed prior to step 430.In another example step 430 and step 440 can execute prior to step 410 and step 420.For another example step 450 and step 460 may be performed simultaneously.

In some embodiments, the first image: rotary collimator 31 to different angle can be obtained in the following way, led to The image under the acquisition different angle of imaging device 104 is crossed as the first image.

In some embodiments, the first image may include the projected image of the marking plate of rotation, and marking plate follows collimation Device rotation.In step 410 and/or step 420, imaging device 104 can obtain in the following way the first image: by marking plate It is inserted into auxiliary tray 32, rotary collimator 31, imaging device 104 is in the first source image away from d1 or the second source image away from acquisition at d2 The projected image of one or more marking plates.In some more specific embodiments, treatment head 103 and imaging device 104 can be with Under the drive of rotating part 102, the first image is obtained at different rack angles.

In some embodiments, the first image may include the tungsten door (Jaw) and/or multi-diaphragm collimator (Multi- of rotation Leaf Collimator, MLC) projected image.That is, in this embodiment it is possible to without being inserted into marking plate, but First rotary shaft is directly determined to the projected image of 31b to 31a and/or beam stop using the beam stop in collimator 31 Position.Specifically, in rotary collimator 31, beam stop can be according to collimator 31 to 31b to 31a and/or beam stop Rotation, imaging device 104 can the first source image away from d1 at acquisition one or more beam stop to 31a and/or beam stop To the projected image of 31b.Similarly, treatment head 103 and imaging device 104 can be under the drives of rotating part 102, in difference Rack angle obtain rotation tungsten door and/or multi-diaphragm collimator projected image, to obtain first image.It is appreciated that by The tungsten door of rotation and/or the projected image of multi-diaphragm collimator are contained in the first image, certain elements are found in projected image Rotation center, that is, can determine that the first rotary shaft position that rotary shaft 30 projects on imaging device 104.

In some embodiments, the second image may include the projected image of correction model body.Correction model body for example can be BB die body.In step 430 and/or step 440, imaging device 104 obtains the mode and 200 phase of beam measurement method of the second image Together, therefore not reinflated description herein.

Step 450, step 460 and step 470 respectively in beam measurement method 200 step 210, step 220 and step Rapid 230 is essentially identical, therefore is not repeated to describe.

In some embodiments, passing through beam measurement method 200, beam measurement method 300 and beam measurement method 400 One of or it is a variety of measurement obtain deviation of the beam axis 40 relative to rotary shaft 30 after, adjustable radiotherapy equipment 100 In associated components, such as adjustment target position etc., so that beam axis 40 and the relationship of rotary shaft 30 is met the requirements.

Figure 10 is the flow diagram of the method for inspection of the radiotherapy equipment of some embodiments of the invention.With reference to Figure 10 institute Show, the method for inspection 500 of radiotherapy equipment includes:

Step 510: determining deviation of the beam axis relative to rotary shaft；

Step 520: will deviate from being compared with preset value, determine and deviate whether in preset value.

Step 510 can be by beam measurement method 200, beam measurement method 300 and beam measurement method 400 It is one or more to determine deviation of the beam axis relative to rotary shaft.

In step 520, if deviateing within preset value, it is determined that deviate acceptable；If deviating more than preset value, it is determined that Deviate unacceptable.

Figure 11 is the flow diagram of the calibration method of the radiotherapy equipment of some embodiments of the invention.With reference to Figure 11 institute Show, the calibration method 600 of radiotherapy equipment includes:

Step 610: determining deviation of the beam axis relative to rotary shaft；

Step 620: according to the position for deviateing component relevant to deviation in adjustment radiation device.

Step 610 can be by beam measurement method 200, beam measurement method 300 and beam measurement method 400 It is one or more to determine deviation of the beam axis relative to rotary shaft.

Associated components in step 620, adjustable radiotherapy equipment 100, such as position, the tune of adjustment accelerating tube The position of whole target or other position of components in adjustment treatment head etc., make beam axis 40 and the relationship of rotary shaft 30 meet the requirements. The position for adjusting associated components can be realized by controlling the movement of movable part, can also carry out reality by artificial adjustment It is existing.

In some embodiments, passing through beam measurement method 200, beam measurement method 300 and beam measurement method 400 One of or it is a variety of measurement obtain deviation of the beam axis 40 relative to rotary shaft 30 after, available beam centre information, and Beam centre information be can use to calculate the flatness of beam.

Figure 12 is the flow diagram of the beam method of inspection of some embodiments of the invention.The beam method of inspection 700 can be with It is performed in beam measurement device 107.The beam method of inspection 200 may include steps of:

Step 710: the beam is determined away from an at least image for acquisition at least one source image based on imaging device The rotary shaft of beam axis and the collimator projected on the imaging device between at least one offset distance.

Imaging device 104 is at least one source image away from an available at least image.Based on an at least image The position that the rotary shaft of the beam axis and the collimator that can determine the beam respectively projects on the imaging device.Into One step, between the rotary shaft of the beam axis and the collimator that can determine the beam projects on the imaging device At least one offset distance.

In some embodiments, imaging device 104 only can obtain one or more away from (as shown in figure 15) in a source image Open image.Based on one or more image determine respectively the beam beam axis and the collimator rotary shaft described The position projected on imaging device.Further, imaging device 104 can determine the beam beam axis and the collimator Rotary shaft projected on the imaging device between one or more offset distances.

It in some embodiments, can be under different rack angles, at least one source image away from (for example, the first source in Fig. 4 Image distance or the second source image away from) position obtains an at least image respectively with the beam axis under the different rack angles of determination relative to rotation Axis projected on the imaging device between offset distance.

Specifically, the specific implementation of step 710 is referred to Figure 13 and its associated description.

Step 720: based at least one described offset distance and preset value, determining the beam axis relative to the rotation Whether the deviation of axis is within preset value.

When the beam axis relative to the rotary shaft deviation when other than preset value, adjust in the radiation device with The position for deviateing relevant component；Otherwise, component relevant to the deviation in the radiation device is not adjusted.

In some embodiments, in step 720, if the same source image away from place determine the beam beam axis and The rotary shaft of the collimator projected on the imaging device between at least one offset distance, then can determine described penetrate Deviation of the beam axis relative to the rotary shaft, the deviation include between beam axis projects on imaging device relative to rotary shaft Offset.In such a case it is possible to directly at least one described offset distance is compared with preset value, if it is described at least one Offset distance can then determine at least one described source image is away from position, beam axis is relative to rotary shaft in preset value Deviation can receive；The associated components in adjustment radiotherapy equipment 100 are not needed.If at least one described offset distance is not In preset value, then it can determine at least one described source image is away from position, beam axis can not relative to the deviation of rotary shaft Receive；It needs to adjust the associated components in radiotherapy equipment 100, such as adjusts the position of accelerating tube, adjusts the position of target Or other position of components in adjustment treatment head etc., so that beam axis 40 and the relationship of rotary shaft 30 is met the requirements.Adjust dependent part The position of part can be realized by controlling the movement of movable part, can also be realized by artificial adjustment.

In some embodiments, the average value of at least one offset distance can be first determined.The average value It can be calculated by arithmetic average, weighted average etc..And then compare the average value whether in preset value.

In some embodiments, it can be determined based on the related data counted in history radiation therapy process described default Value.For example, can count between beam axis of the different source images away from position projects on imaging device 104 relative to rotary shaft Offset distance can be by offset distance when receiving.In some embodiments, can determine can in the case where different source images are away from position The average value of offset distance when being received may thereby determine that each source image is corresponding default away from position as the preset value Value.For example, the first source image corresponds to preset value m1 away from d1；Second source image corresponds to preset value m2 away from d2；Third source image is corresponding pre- away from d3 If value m3 ..., the n-th source image correspond to preset value mn away from dn.

When determining that the beam axis 40 of the beam and the rotary shaft 30 of the collimator exist at some source image position At least one offset distance on the imaging device 104 between projection, then can be by least one offset distance and the source Corresponding preset value is compared at image position, so that it is determined that the rotary shaft 30 of the beam axis 40 of the beam and the collimator Deviation whether can be received.

It is set compared to beam measurement method 200, beam measurement method 300 and beam measurement method 400 and radiotherapy The standby method of inspection 500 does not need to determine in two or two source image penetrating away from beam described at position in this embodiment The rotary shaft 30 of beam axis 40 and the collimator project on the imaging device between offset distance determine beam axis 40 With the departure degree of rotary shaft 30, the beam method of inspection 700 can be only it needs to be determined that go out to penetrate in a source image away from described at position The beam axis 40 of beam and the rotary shaft 30 of the collimator projected on the imaging device between at least one offset distance, And be compared at least one offset distance with the preset value, that is, it can determine that the beam axis 40 of the beam and described Whether the departure degree of the rotary shaft 30 of collimator can be received.

It should be noted that in some embodiments, in step 720, if determining described penetrate away from place in multiple source images The rotary shaft of the beam axis of beam and the collimator projected on the imaging device between at least one offset distance, then may be used To determine that deviation of the beam axis relative to the rotary shaft, the deviation include beam axis according to beam measurement method 200 The inclination angle of offset and beam axis relative to rotary shaft between being projected on imaging device relative to rotary shaft.In the feelings Under condition, directly at least one described offset distance and preset value (preset value is offset distance size) can be compared, Or the inclination angle is compared with preset value (preset value is offset distance size).If described deviate in preset value, It can determine that beam axis can receive relative to the deviation of rotary shaft；The phase in adjustment radiotherapy equipment 100 is not needed Close component.If the deviation can determine that beam axis is unacceptable relative to the deviation of rotary shaft not in preset value；Need The associated components in radiotherapy equipment 100 are adjusted, such as adjust the position of accelerating tube, the position for adjusting target or adjustment treatment Other position of components etc. in head, make beam axis 40 and the relationship of rotary shaft 30 meet the requirements.The position for adjusting associated components can To be realized by the movement for controlling movable part, can also be realized by artificial adjustment.

It should be noted that the operation order of beam measurement method 700 shown in Figure 12 is not intended to limit the present invention.Example Such as, step 710 and step 720 may be performed simultaneously.In another example step 720 can be executed prior to step 710.

Figure 13 is the flow diagram of at least one offset distance of the determination of some embodiments of the invention.With reference to Figure 13 institute Show, step 710 may include:

Step 711, the rotary shaft is determined away from least first image for acquisition in the first source image based on imaging device The rotary shaft position projected on the imaging device.

Step 712, the beam axis is determined away from least second image for acquisition in the first source image based on imaging device The Beam axis position projected on the imaging device.

Step 713, offset distance is calculated according to the rotary shaft position and the Beam axis position.

In step 711, the first image can be any projection position that can determine rotary shaft 30 on imaging device 104 The image set.Such as can obtain the first image in the following way: rotary collimator 31 to different angle passes through imaging device Image under 104 acquisition different angles is as the first image.

In some embodiments, the first image may include the projected image of the marking plate of rotation, and marking plate follows collimation Device rotation.Specifically, it is referred to Fig. 6 and its associated description, details are not described herein.

In some embodiments, the first image may include the tungsten door (Jaw) and/or multi-diaphragm collimator (Multi- of rotation Leaf Collimator, MLC) projected image.Specifically, it is referred to Fig. 6 and its associated description, details are not described herein.

In step 712, the second image can be any projection position that can determine beam axis 40 on imaging device 104 The image set.

In some embodiments, the second image may include the projected image of correction model body.Correction model body can be BB mould Body.Specifically, it is referred to Fig. 6 and its associated description, details are not described herein.

In some embodiments, treatment head 103 and imaging device 104 can be under the drives of rotating part 102, in difference Rack angle obtain the second image.That is, the second image can be the school that imaging device 104 acquires under different rack angles The projected image of positive die body.Specifically, it is referred to Fig. 6 and its associated description, details are not described herein.

Figure 14 is the flow diagram of the calibration method of the radiotherapy equipment of some embodiments of the invention.With reference to Figure 14 institute Show, the calibration method 800 of radiotherapy equipment includes:

Step 810, determine beam axis and rotary shaft at least one source image away from being on imaging device between projection extremely A few offset distance.

In step 810, deviation of the beam axis relative to rotary shaft can be determined by the beam method of inspection 700.Tool Body, it is referred to Figure 12 and its associated description, details are not described herein.

Step 820, it is adjusted in radiation device according at least one described offset distance and deviates phase with beam axis and rotary shaft The position of the component of pass.

Associated components in step 820, adjustable radiotherapy equipment 100, such as position, the tune of adjustment accelerating tube The position of whole target or other position of components in adjustment treatment head etc., make beam axis 40 and the relationship of rotary shaft 30 meet the requirements. The position for adjusting associated components can be realized by controlling the movement of movable part, can also carry out reality by artificial adjustment It is existing.

Figure 16 is a kind of module map of beam verifying attachment 1600 of some embodiments of the invention.

Beam verifying attachment 1600 includes determining module 1610, judgment module 1620 and adjustment module 1630.

Beam verifying attachment 1600 may be adapted to the beam for examining radiation device, and the radiation device includes at least radiation Source, collimator and the imaging device being oppositely arranged with the radiation source, the radiation source is for generating the beam, the collimation Device is used to limit beam to the beam.

Determining module 1610 can be used for based on the imaging device at least one figure of at least one source image away from acquisition As determine the beam beam axis and the collimator rotary shaft projected on the imaging device between at least one Offset distance.

Judgment module 1620 can be used for determining the beam axis phase based at least one described offset distance and preset value For the rotary shaft deviation whether within preset value.

Adjustment module 1630 can be used for when the beam axis relative to the rotary shaft deviation when other than preset value, Adjust the position of component relevant to the deviation in the radiation device；Otherwise, in the radiation device with the deviation Relevant component does not adjust.

In some embodiments, at least one described source image away from for a source image away from；An at least image is one Image；At least one described offset distance is an offset distance.

In some embodiments, the determining module 1610 is also used in each source image away from place: being based on the imaging device The rotary shaft that the rotary shaft projects on the imaging device is determined away from least first image for acquisition in the source image Position；Based on the imaging device the source image away from least second image for acquisition determine the beam axis it is described at As the Beam axis position projected on device；And the offset distance is calculated according to the rotary shaft position and the Beam axis position From.

In some embodiments, the first image obtains in the following way: rotate the collimator to different angle, The image under different angle is acquired as the first image by the imaging device.In some embodiments, described second Image is the projected image of the correction model body acquired by the imaging device.In some embodiments, the first image can Think the projected image of at least one of marking plate, tungsten door and multi-diaphragm collimator.In some embodiments, second image can Think the projected image for the correction model body that the imaging device acquires under different rack angles.

Basic conception is described above, it is clear that those skilled in the art, foregoing invention discloses only As an example, and not constituting the restriction to the application.Although do not clearly state herein, those skilled in the art may The application is carry out various modifications, improve and is corrected.Such modification, improvement and amendment are proposed in this application, so such Modification improves, corrects the spirit and scope for still falling within the application example embodiment.

Meanwhile the application has used particular words to describe embodiments herein.Such as " one embodiment ", " one implements Example ", and/or " some embodiments " mean a certain feature relevant at least one embodiment of the application, structure or feature.Cause This, it should be highlighted that and it is noted that " embodiment " or " an implementation referred to twice or repeatedly in this specification in different location Example " or " alternate embodiment " are not necessarily meant to refer to the same embodiment.In addition, in one or more embodiments of the application Certain features, structure or feature can carry out combination appropriate.

In addition, it will be understood by those skilled in the art that the various aspects of the application can be by several with patentability Type or situation are illustrated and described, the combination or right including any new and useful process, machine, product or substance Their any new and useful improvement.Correspondingly, the various aspects of the application can completely by hardware execute, can be complete It is executed, can also be executed by combination of hardware by software (including firmware, resident software, microcode etc.).Hardware above is soft Part is referred to alternatively as " data block ", " module ", " engine ", " unit ", " component " or " system ".In addition, the various aspects of the application The computer product being located in one or more computer-readable mediums may be shown as, which includes computer-readable program Coding.

Computer-readable signal media may include the propagation data signal containing computer program code in one, such as A part in base band or as carrier wave.The transmitting signal may there are many forms of expression, including electromagnetic form, light form etc. Deng or suitable combining form.Computer-readable signal media can be any meter in addition to computer readable storage medium Calculation machine readable medium, the medium can be realized by being connected to an instruction execution system, device or equipment communication, propagate or Transmit the program for using.Program coding in computer-readable signal media can be carried out by any suitable medium It propagates, the combination including radio, cable, fiber optic cables, RF or similar mediums or any of above medium.It is computer-readable to deposit Storage media can be used for storing computer-readable program coding, may include one of hard disk, memory and memory or more Person.

Computer program code needed for the operation of the application each section can use any one or more programming language, Including Object-Oriented Programming Language such as Java, Scala, Smalltalk, Eiffel, JADE, Emerald, C++, C#, VB.NET, Python etc., conventional procedural programming language for example C language, Visual Basic, 2003 Fortran, Perl, COBOL 2002, PHP, ABAP, dynamic programming language such as Python, Ruby and Groovy or other programming languages etc..The program coding can be complete Entirely on the user computer run run on the user computer as independent software package or partially in subscriber computer Upper operation part runs in remote computer or runs on a remote computer or server completely.In the latter cases, remotely Computer can be connect by any latticed form with subscriber computer, such as local area network (LAN) or wide area network (WAN), or even It is connected to outer computer (such as passing through internet), or in cloud computing environment, or is serviced as service using such as software (SaaS)。

In addition, except clearly stating in non-claimed, the sequence of herein described processing element and sequence, digital alphabet Using or other titles use, be not intended to limit the sequence of the application process and method.Although by each in above-mentioned disclosure Kind of example discuss it is some it is now recognized that useful inventive embodiments, but it is to be understood that, such details only plays explanation Purpose, appended claims are not limited in the embodiment disclosed, on the contrary, claim is intended to cover and all meets the application The amendment and equivalent combinations of embodiment spirit and scope.For example, although system component described above can be set by hardware It is standby to realize, but can also be only achieved by the solution of software, such as pacify on existing server or mobile device Fill described system.

Similarly, it is noted that in order to simplify herein disclosed statement, to help real to one or more invention Apply the understanding of example, above in the description of the embodiment of the present application, sometimes by various features merger to one embodiment, attached drawing or In descriptions thereof.But this disclosure method is not meant to mention in aspect ratio claim required for the application object And feature it is more.In fact, the feature of embodiment will be less than whole features of the single embodiment of above-mentioned disclosure.

The number of description ingredient, number of attributes is used in some embodiments, it should be appreciated that such to be used for embodiment The number of description has used qualifier " about ", " approximation " or " generally " etc. to modify in some instances.Unless in addition saying It is bright, " about ", " approximation " or " generally " show that the number allows to have ± bright the variation.Correspondingly, in some implementations In example, numerical parameter used in description and claims is approximation, approximation spy according to needed for separate embodiment Point can change.In some embodiments, numerical parameter is considered as defined significant digit and is retained using general digit Method.Although the Numerical Range and parameter in some embodiments of the application for confirming its range range are approximation, specific In embodiment, being set in for such numerical value is reported as precisely as possible in feasible region.

Although the present invention is described with reference to current specific embodiment, those of ordinary skill in the art It should be appreciated that above embodiment is intended merely to illustrate the present invention, can also make in the case where no disengaging spirit of that invention Various equivalent change or replacement out, therefore, as long as to the variation of above-described embodiment, change in spirit of the invention Type will all be fallen in the range of following claims.

Claims

1. a kind of beam method of inspection, suitable for examining the beam of radiation device, the radiation device includes at least radiation source, collimation Device and the imaging device being oppositely arranged with the radiation source, for generating the beam, the collimator is used for the radiation source Beam is limited to the beam, which comprises

Based on the imaging device at least one source image away from an at least image for acquisition determine the beam beam axis and The rotary shaft of the collimator projected on the imaging device between at least one offset distance；And

Based at least one described offset distance and preset value, determine the beam axis relative to the rotary shaft deviation whether Within preset value.

2. the beam method of inspection according to claim 1, it is characterised in that:

When the beam axis relative to the rotary shaft deviation when other than preset value, adjust in the radiation device with it is described Deviate the position of relevant component；

Otherwise, component relevant to the deviation in the radiation device is not adjusted.

3. the beam method of inspection according to claim 1, which is characterized in that

At least one described source image away from for a source image away from.

4. the beam method of inspection according to claim 1, which is characterized in that based on the imaging device at least one source At least image that image distance obtains respectively determine the beam beam axis and the collimator rotary shaft in the imaging On device projection between at least one offset distance include:

In each source image away from place:

Based on the imaging device the source image away from least first image for acquisition determine the rotary shaft it is described at As the rotary shaft position projected on device；

Based on the imaging device the source image away from least second image for acquisition determine the beam axis it is described at As the Beam axis position projected on device；And

The offset distance is calculated according to the rotary shaft position and the Beam axis position.

5. the beam method of inspection according to claim 4, it is characterised in that:

The first image obtains in the following way: rotating the collimator to different angle, is adopted by the imaging device Collect the image under different angle as the first image；And/or

Second image is the projected image of the correction model body acquired by the imaging device.

6. a kind of beam checking system, suitable for examining the beam of radiation device, the radiation device includes at least radiation source, collimation Device and the imaging device being oppositely arranged with the radiation source, for generating the beam, the collimator is used for the radiation source Beam is limited to the beam, the system comprises:

Determining module, for based on the imaging device at least one source image away from least image of acquisition determine described in penetrate The rotary shaft of the beam axis of beam and the collimator projected on the imaging device between at least one offset distance；And

Judgment module, for determining the beam axis relative to the rotation based at least one described offset distance and preset value Whether the deviation of shaft is within preset value.

7. beam checking system according to claim 6, which is characterized in that the determining module is also used in each source At image distance:

8. a kind of beam measurement method, suitable for measuring the beam of radiation device, the radiation device includes at least radiation source, collimation Device and the imaging device being oppositely arranged with the radiation source, for generating the beam, the collimator is used for the radiation source Beam is limited to the beam, which comprises

Based on the imaging device multiple and different source images away from multiple images obtained respectively determine the beam beam axis and The rotary shaft of the collimator projected on the imaging device between multiple distances；And

According to the multiple different source images away from the deviation with the determining beam axis of the multiple distance relative to the rotary shaft.

9. beam measurement method according to claim 8, which is characterized in that based on the imaging device in multiple and different sources Multiple images that image distance obtains respectively determine the beam beam axis and the collimator rotary shaft in the imaging device Multiple distances between upper projection include:

In each source image away from place:

The distance is calculated according to the rotary shaft position and the Beam axis position.

10. beam measurement method according to claim 9, which is characterized in that the first image obtains in the following way It takes: rotating the collimator to different angle, the image under different angle is acquired as described first by the imaging device Image.

11. beam measurement method according to claim 9, which is characterized in that the first image be marking plate, tungsten door and The projected image of at least one of multi-diaphragm collimator.

12. beam measurement method according to claim 9, which is characterized in that second image is to pass through the imaging The projected image of the correction model body of device acquisition.

13. beam measurement method according to claim 9, which is characterized in that second image is the imaging device The projected image of the correction model body acquired under different rack angles.

14. beam measurement method according to claim 8, which is characterized in that the deviation includes:

Inclination angle of the beam axis relative to the rotary shaft；And/or

Offset of the beam axis relative to the rotary shaft.

15. beam measurement method according to claim 14, which is characterized in that it is described offset be the beam axis with it is described Rotary shaft projected on target plane between distance.

16. beam measurement method according to claim 14, which is characterized in that based on the multiple different source images away from and institute Multiple distances are stated, determine the inclination angle and the offset using geometrical relationship.

17. beam measurement method according to claim 14, which is characterized in that based on the multiple different source images away from and institute Multiple distances are stated, multiple inclination angle initial values and multiple offset initial values are determined using geometrical relationship, to the inclination angle initial value and institute It states offset initial value and is fitted the determining inclination angle and the offset.

18. a kind of beam measurement method, suitable for measuring the beam of radiation device, the radiation device includes at least radiation source, standard Straight device and the imaging device being oppositely arranged with the radiation source, the radiation source are used for generating the beam, the collimator In to beam limit beam, which comprises

The imaging device is in the first source image away from acquisition at least first image；

The imaging device is adapted to determine that described in the second source image away from an at least the first image, the first image is obtained The position that the rotary shaft of collimator projects on the imaging device；

The imaging device is in first source image away from acquisition at least second image；

The imaging device is adapted to determine that in second source image away from least second image, second image is obtained The position that the beam axis of the beam projects on the imaging device；

Determined according to the first image and second image, the imaging device be located at first source image away from when, it is described The first distance that beam axis and the rotary shaft project on the imaging device；

Determined according to the first image and second image, the imaging device be located at second source image away from when, it is described The second distance that beam axis and the rotary shaft project on the imaging device；And

According to the first distance, the second distance, first source image away from second source image away from the determination beam Deviation of the axis relative to the rotary shaft.

19. beam measurement method according to claim 18, which is characterized in that according to the first image and described second Image determines, the imaging device be located at first source image away from when, the beam axis and the rotary shaft are filled in the imaging The first distance for setting projection includes:

The rotary shaft is determined away from an at least the first image for acquisition in first source image according to the imaging device The first rotary shaft position projected on the imaging device；

The beam axis is determined away from least second image for acquisition in first source image according to the imaging device The first Beam axis position projected on the imaging device；And

The first distance is calculated according to first rotary shaft position and first Beam axis position.

20. beam measurement method according to claim 18, which is characterized in that according to the first image and described second Image determines, the imaging device be located at second source image away from when, the beam axis and the rotary shaft are filled in the imaging The second distance for setting projection includes:

The rotary shaft is determined away from an at least the first image for acquisition in second source image according to the imaging device The second rotary shaft position projected on the imaging device；

The beam axis is determined away from least second image for acquisition in second source image based on the imaging device The second Beam axis position projected on the imaging device；And

The second distance is calculated according to second rotary shaft position and second Beam axis position.

21. beam measurement method according to claim 18, which is characterized in that the first image obtains in the following way It takes: rotating the collimator to different angle, the image under different angle is acquired as described first by the imaging device Image.

22. beam measurement method according to claim 18, which is characterized in that the first image is marking plate, tungsten door With the projected image of at least one of multi-diaphragm collimator.

23. beam measurement method according to claim 18, which is characterized in that second image is the imaging device The projected image of the correction model body acquired under different rack angles.

24. beam measurement method according to claim 18, which is characterized in that the deviation includes:

Inclination angle of the beam axis relative to the rotary shaft；And/or

Offset of the beam axis relative to the rotary shaft.

25. beam measurement method according to claim 24, which is characterized in that it is described offset be the beam axis with it is described Rotary shaft projected on target plane between distance.

26. a kind of method of inspection of radiation device, comprising:

Using beam axis as described in the beam measurement method determination as described in any one of claim 8-25 relative to the rotation The deviation of axis；And

The deviation is compared with preset value, determines the deviation whether within preset value.

27. a kind of calibration method of radiation device, comprising:

Using beam axis as described in the beam measurement method determination as described in any one of claim 1-5 or 8-25 relative to described The deviation of rotary shaft；And

According to the position for deviateing component relevant to the deviation in the adjustment radiation device.

28. a kind of beam measurement device, comprising:

Computer readable storage medium, for storing the instruction that can be executed by processor；

Processor, for executing described instruction to realize the method as described in any one of claim 1 to 5 or 8 to 27.

29. a kind of computer readable storage medium, is stored thereon with computer instruction, wherein when computer instruction is held by processor When row, the method as described in any one of claim 1 to 5 or 8 to 27 is realized.