CN110066733A - Stem cell cultivates robot - Google Patents
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- CN110066733A CN110066733A CN201910457518.0A CN201910457518A CN110066733A CN 110066733 A CN110066733 A CN 110066733A CN 201910457518 A CN201910457518 A CN 201910457518A CN 110066733 A CN110066733 A CN 110066733A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/48—Automatic or computerized control
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
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- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/09—Means for pre-treatment of biological substances by enzymatic treatment
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/04—Cell isolation or sorting
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M99/00—Subject matter not otherwise provided for in other groups of this subclass
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Abstract
A kind of stem cell culture robot, comprising: shell, inside have a cavity；Antigen repairing device is set in cavity, for pre-processing to biological tissue；Main operation platform is set in the cavity, and the main operation platform is connect with the Antigen repairing device, is transferred to the main operation platform by the pretreated biological tissue of the Antigen repairing device and is cultivated.After stem cell culture provided by the invention robot can pre-process biological tissue by the Antigen repairing device being arranged in cavity, by being handled pretreated biological tissue in main operation platform to obtain stem cell and cultivate, so that becoming more convenient and quick to the operation of stem cell, and the pollution of outer bound pair biological tissue can be prevented, improve the culture qualification rate of stem cell.
Description
Technical field
The invention belongs to medical equipment fields, specifically disclose a kind of stem cell culture robot.
Background technique
Stem cell is that a kind of multipotential cell with the of self-replication capacity can be divided into one under certain conditions
The cell of kind or Various Tissues or organ.Stem cell can be divided into embryonic stem cell and adult stem cell, usually round or ellipse
Circle, cell volume is smaller, but nucleus is larger, mostly euchromatin, and telomerase activation with higher.
In the incubation of stem cell, to guarantee the good culture effect of cell, cell is needed to be dispersed in culture
In liquid, cell will also come into full contact with culture solution, guarantee that cell grows required nutriment supply.In order to obtain stem cell, need
Biological tissue is operated, cell separation etc., in operation, it is easy to which contaminated device, operation are more inconvenient.
Summary of the invention
The purpose of the present invention is to provide a kind of stem cells to cultivate robot, in order to carry out operation acquisition to biological tissue
Stem cell is cultivated.
For this purpose, the present invention provides a kind of stem cells to cultivate robot, comprising:
Shell, inside have a cavity；
Antigen repairing device is set in cavity, for pre-processing to biological tissue；
Main operation platform is set in the cavity, and the main operation platform is connect with the Antigen repairing device, by institute
It states the pretreated biological tissue of Antigen repairing device and is transferred to the main operation platform and cultivated.
Preferably, the pretreatment unit includes:
First computerizing management, for dispensing amine enzyme material；
Antigen repairing device is connect with first computerizing management, is stored in the pre- place of the tissue in the biological tissue
After managing device, the amine enzyme material is configured in the Antigen repairing device and is pre-processed；
First waste liquid processor is connect with the Antigen repairing device, useless in the Antigen repairing device for being discharged
Liquid.
Preferably, further includes:
Transmission belt, set on the roof of the cavity；
Mechanical arm is connected to the transmission belt, for being moved to Antigen repairing device position in the transmission belt
When, shear the biological tissue being configured in the Antigen repairing device.
Preferably, the end of the mechanical arm is additionally provided with sampling sample injector, for the Antigen repairing device and institute
Main operation platform is stated at least one to be sampled and be loaded.
It preferably, further include centrifuge, for carrying out centrifugally operated to the biological tissue in order to the biological tissue
It is handled on the Antigen repairing device or main operation platform.
Preferably, further includes:
Second computerizing management is connect with the main operation platform, for carrying out for the main operation platform with liquid；
Second waste liquid processor is connect with the main operation platform, the waste liquid for being discharged in the main operation platform.
It preferably, further include fluorescence detector and digital management platform, the fluorescence detector is for observing the main behaviour
Make the biological tissue at center, the digital management platform and the fluorescence detector and the transmission band connection, for controlling
State fluorescence detector and the transmission belt.
Preferably, further includes:
Incubator is connect with the main operation center, for cultivating the biological tissue crossed through the main operation center processing；
Discharging bin is connect with the incubator, for biological tissue described in the extract from the incubator；
Tube assembly is frozen, for freezing the biological tissue crossed through the main operation center processing.
Preferably, further includes:
Ultraviolet disinfection monitor, for carrying out disinfection by ultraviolet light in the cavity；
Zone of negaive pressure monitor for flowing, for monitoring negative pressure and laminar flow in the cavity；
Carbon dioxide connector is connected to the cavity, for carbon dioxide to be added into the cavity.
Preferably, the shell is the shell made of transparent material.
Compared with prior art, stem cell provided by the invention culture robot can be by the tissue that is arranged in cavity
After pretreatment unit pre-processes biological tissue, by handling in main operation platform pretreated biological tissue
It is cultivated with obtaining stem cell, so that becoming more convenient and quick to the operation of stem cell, and outer bound pair can be prevented
The pollution of biological tissue improves the culture qualification rate of stem cell.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of stem cell culture robot of the present invention；
Fig. 2 be in Fig. 1 II-II to structural schematic diagram；
In figure:
10- shell；11- carbon dioxide connector；12- transmission belt；13- mechanical arm；20- digital management platform；30- discharging
Storehouse；31- incubator；32- freezes tube assembly；40- main operation platform；The second computerizing management of 41-；The second waste liquid processor of 42-；
43- centrifuge；50- fluorescence detector；60- Antigen repairing device；The first computerizing management of 61-；62- Antigen repairing device；63-
First waste liquid processor；70- ultraviolet disinfection monitor；71- zone of negaive pressure monitor for flowing.
Specific embodiment
With reference to the accompanying drawing, the present invention will be further described.
Fig. 1 is a kind of structural schematic diagram of stem cell culture of the present invention robot, Fig. 2 be in Fig. 1 II-II to knot
Structure schematic diagram (top surface of shell 10 is omitted).As depicted in figs. 1 and 2, stem cell culture robot includes shell 10, tissue
Pretreatment unit 60, main operation platform 40, transmission belt 12 and mechanical arm 13, fluorescence detector 50, digital management platform 20, training
It supports case 31, discharging bin 30, freeze tube assembly 32, ultraviolet disinfection monitor 70, zone of negaive pressure monitor for flowing 71 and carbon dioxide connector
11。
There is a cavity, above-mentioned each component is located in the cavity or is installed on the side of the cavity inside the shell 10
Wall.In present embodiment, the shell 10 is made of transparent material, being capable of externally visibly internal each component and its operation feelings
Condition and the culture situation of biological tissue.
Antigen repairing device 60 is set in the cavity of shell 10, for being pre-processed to biological tissue, the pre- place
Reason includes operating to fragmentation, disinfection, digestion etc..In present embodiment, the pretreatment unit includes the first computerizing management 61, group
Knit preprocessor 62, the first waste liquid processor 63.First computerizing management 61 is for dispensing amine enzyme material, the Antigen repairing
Device 62 is connect with first computerizing management 61, after the biological tissue is stored in the Antigen repairing device 62, the amine
Enzyme material is configured in the Antigen repairing device 62 and is pre-processed；First waste liquid processor 63 and the pre- place of the tissue
It manages device 62 to connect, the waste liquid for being discharged in the Antigen repairing device 62.It is pre- to enter tissue in flesh tissue such as umbilical cord tissue
After processing unit 60, passed through ethyl alcohol soaking disinfection, then carried out using utensils such as scissors with the mechanical arm 13 in transmission belt 12
It shears to isolate the tissue of needs, is transferred to master operating station after pancreatin or collagenase digesting.
Transmission belt 12 and mechanical arm 13 are additionally provided on the shell 10, the transmission belt 12 is set to the top of the cavity
Wall, the mechanical arm 13 are connected to the transmission belt 12, for being moved to the Antigen repairing device in the transmission belt 12
When 62 position, the biological tissue being configured in the Antigen repairing device 62 is sheared.In present embodiment, the mechanical arm
13 end is additionally provided with sampling sample injector, for being sampled to the Antigen repairing device 62 and the main operation platform 40 and
At least one sample-adding.
Main operation platform 40 is set in the cavity, and the main operation platform 40 connects with the Antigen repairing device 60
It connects, the main operation platform 40 is transferred to by the pretreated biological tissue of the Antigen repairing device 60 and is cultivated.
In addition, stem cell culture robot further includes the second computerizing management 41 and the second Waste processor, described the
Two computerizing managements 41 are connect with the main operation platform 40, for carrying out for the main operation platform 40 with liquid.Described second is useless
Liquid processor 42 is connect with the main operation platform 40, the waste liquid for being discharged in the main operation platform 40.It is flat in main operation
Platform 40 carries out plus culture medium culture, and replaces different culture medium according to various requirement, or cell factor is added, culture induction point
Change, such as changes liquid after culture three days.
The centrifuge 43 is used to carry out centrifugally operated to the biological tissue in order to which the biological tissue is at described group
It knits and is handled on pretreatment unit 60 or main operation platform 40.It can according to need at the end of induction, such as directly in cell
It transmits and comes out in bottle, then be transferred to Antigen repairing module and digested, cell suspension is made.The cell suspension can be taken out
With, be resuspended after can also being centrifuged using frozen stock solution, then transmission come out being frozen.In addition, centrifuge 43 is in each digestion
Require using.
The fluorescence detector 50 is used to observe the biological tissue at the main operation center, can be optical microscopy, glimmering
Light microscope etc..The digital management platform 20 is connect with the fluorescence detector 50 and the transmission belt 12, for controlling
State fluorescence detector 50 and the transmission belt 12.Cultivating centre in main operation platform 40 can be for transmission to built-in fluorescence detector
50 are observed, and the automatic camera time of fluorescence detector 50 (such as optical microscopy) can also be arranged, such as 8 hours clap one
It is secondary, 24 hours, 48 hours, to analyze its growth and differentiation.Preferably, which is also possible to fluorescence microscopy
Mirror can be added antibody label in main operation screen platform, then be transferred to the inner analysis of fluorescence detector 50, see molecular change.
The incubator 31 is connect with the main operation center, for cultivating the biology crossed through the main operation center processing
Tissue.The discharging bin 30 is connect with the incubator 31, for biological tissue described in the extract from the incubator 31.Institute
It states and freezes tube assembly 32, for freezing the biological tissue crossed through the main operation center processing.
It can also include ultraviolet disinfection monitor 70, negative pressure laminar flow prison in the cavity of the shell 10 in present embodiment
Control device 71.The ultraviolet disinfection monitor 70 is used for carrying out disinfection by ultraviolet light in the cavity.The zone of negaive pressure monitor for flowing
71, for monitoring negative pressure and laminar flow in the cavity.In some embodiments, which can also include carbon dioxide
Connector 11, the carbon dioxide connector 11 are connected to the cavity, for carbon dioxide to be added into the cavity.
The course of work for the stem cell culture robot that above embodiment described in detail below is related to.
Firstly, fresh tissue (such as umbilical cord tissue) is put into Antigen repairing device 62, after ethyl alcohol soaking disinfection,
The biological tissue is shredded by the scissors hand of the mechanical arm 13 in transmission belt 12, isolates the tissue of needs.Then,
After first computerizing management 61 configures pancreatin into the Antigen repairing device 62 or clostridiopetidase A digests the biological tissue, pass
Transport to main operation platform 40.
Then, it is cultivated by the second computerizing management 41 to main operation platform 40 plus culture medium, and according to various requirement
Different culture medium is replaced, or cell factor is added, culture induction differentiation, such as liquid is changed after culture three days.During the cultivation process,
The biological tissue can also be transferred to built-in fluorescence detector 50 to observe, oneself of fluorescence detector 50 also can be set
Dynamic photo opporunity, for example, clap within 8 hours it is primary, 24 hours, 48 hours, to analyze its growth and differentiation.In some embodiments
In, which can be fluorescence microscope, antibody label can be added in main operation platform 40, then be transferred to fluorescence
It is analyzed in microscope, sees molecular change.
It can according to need at the end of induction, such as transmit and come out directly in cell bottle, prepare to use, or pass again
It is defeated to be digested to Antigen repairing module, cell suspension is made.Cell suspension can take out use, and centrifuge also can be used
It is resuspended after 43 centrifugations using frozen stock solution, then transmission comes out and frozen.Wherein, it in digestion city, is required to using centrifuge 43
It is centrifuged.
In above-mentioned operating process, need ultraviolet disinfection monitor 70 in the cavity carry out disinfection by ultraviolet light and
Zone of negaive pressure monitor for flowing 71 monitors negative pressure and laminar flow conditions in the cavity.
The stem cell culture robot that present embodiment provides can be by the Antigen repairing device that is arranged in cavity
After 60 pairs of biological tissues pre-process, by being handled pretreated biological tissue to obtain in main operation platform 40
Stem cell is cultivated, so that becoming more convenient and quick to the operation of stem cell, and can prevent outer bound pair biology group
The pollution knitted improves the culture qualification rate of stem cell.
It should be understood that the invention is not limited to above embodiment, it is all to various changes or modifications of the invention not
Be detached from the spirit and scope of the present invention, if these modification and variations belong to claim and equivalent technologies range of the invention it
Interior, then the present invention is also implied that comprising these modification and variations.
Claims (10)
1. a kind of stem cell cultivates robot characterized by comprising
Shell, inside have a cavity；
Antigen repairing device is set in cavity, for pre-processing to biological tissue；
Main operation platform is set in the cavity, and the main operation platform is connect with the Antigen repairing device, by described group
It knits the pretreated biological tissue of pretreatment unit and is transferred to the main operation platform and cultivated.
2. stem cell as described in claim 1 cultivates robot, which is characterized in that the pretreatment unit includes:
First computerizing management, for dispensing amine enzyme material；
Antigen repairing device is connect with first computerizing management, is stored in the Antigen repairing device in the biological tissue
Afterwards, the amine enzyme material is configured in the Antigen repairing device and is pre-processed；
First waste liquid processor is connect with the Antigen repairing device, the waste liquid for being discharged in the Antigen repairing device.
3. stem cell as claimed in claim 2 cultivates robot, which is characterized in that further include:
Transmission belt, set on the roof of the cavity；
Mechanical arm is connected to the transmission belt, for cutting when the transmission belt is moved to the Antigen repairing device position
Cut the biological tissue being configured in the Antigen repairing device.
4. stem cell as claimed in claim 3 cultivates robot, which is characterized in that the end of the mechanical arm, which is additionally provided with, to be taken
Sample sample injector, at least one the Antigen repairing device and the main operation platform being sampled and being loaded.
5. stem cell as claimed in claim 4 cultivates robot, which is characterized in that further include centrifuge, for the life
Object tissue carries out centrifugally operated in order to which the biological tissue is handled on the Antigen repairing device or main operation platform.
6. stem cell as claimed in claim 5 cultivates robot, which is characterized in that further include:
Second computerizing management is connect with the main operation platform, for carrying out for the main operation platform with liquid；
Second waste liquid processor is connect with the main operation platform, the waste liquid for being discharged in the main operation platform.
7. stem cell as claimed in claim 6 cultivates robot, which is characterized in that further include fluorescence detector and digital management
Platform, the fluorescence detector are used to observe the biological tissue at the main operation center, the digital management platform and the light
Detector and the transmission band connection are learned, for controlling the fluorescence detector and the transmission belt.
8. stem cell as claimed in claim 7 cultivates robot, which is characterized in that further include:
Incubator is connect with the main operation center, for cultivating the biological tissue crossed through the main operation center processing；
Discharging bin is connect with the incubator, for biological tissue described in the extract from the incubator；
Tube assembly is frozen, for freezing the biological tissue crossed through the main operation center processing.
9. stem cell as claimed in claim 8 cultivates robot, which is characterized in that further include:
Ultraviolet disinfection monitor, for carrying out disinfection by ultraviolet light in the cavity；
Zone of negaive pressure monitor for flowing, for monitoring negative pressure and laminar flow in the cavity；
Carbon dioxide connector is connected to the cavity, for carbon dioxide to be added into the cavity.
10. stem cell as claimed in claim 8 cultivates robot, which is characterized in that the shell is using transparent material system
The shell of work.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910457518.0A CN110066733A (en) | 2019-05-29 | 2019-05-29 | Stem cell cultivates robot |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910457518.0A CN110066733A (en) | 2019-05-29 | 2019-05-29 | Stem cell cultivates robot |
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| CN110066733A true CN110066733A (en) | 2019-07-30 |
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| CN201910457518.0A Pending CN110066733A (en) | 2019-05-29 | 2019-05-29 | Stem cell cultivates robot |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110908329A (en) * | 2019-12-23 | 2020-03-24 | 深圳赛动生物自动化有限公司 | Stem cell feeding and discharging bin control system and control method based on programmable controller |
Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004305148A (en) * | 2003-04-09 | 2004-11-04 | Olympus Corp | Automatic culture apparatus |
| CN1592779A (en) * | 2002-06-13 | 2005-03-09 | 奥林巴斯株式会社 | Culturing apparatus |
| CN102061260A (en) * | 2010-12-01 | 2011-05-18 | 汪华 | Medical automatic cell production device and production method thereof |
| US20130210130A1 (en) * | 2010-04-21 | 2013-08-15 | Octane Biotech, Inc. | Automated cell culture system |
| US20140315303A1 (en) * | 2011-12-07 | 2014-10-23 | Cytover Inc. | Method and device for sample processing |
| WO2015023658A2 (en) * | 2013-08-12 | 2015-02-19 | Invivosciences Inc. | Automated cell culture system and method |
| CN205295360U (en) * | 2015-12-28 | 2016-06-08 | 江苏希瑞干细胞技术有限公司 | Navel cord automated processing device |
| WO2017221155A1 (en) * | 2016-06-20 | 2017-12-28 | Genesis Technologies Limited | Automated cell processing systems and methods |
| CN108048298A (en) * | 2017-12-01 | 2018-05-18 | 何加铭 | A kind of umbilical cord tissue mescenchymal stem cell separator and its control method |
| CN108102914A (en) * | 2017-12-27 | 2018-06-01 | 深圳北科赛动生物机器人有限公司 | Stem cell auto culturing system |
| CN108138130A (en) * | 2015-08-31 | 2018-06-08 | 爱平世股份有限公司 | The method of multipotential stem cell manufacture system and production induced multi-potent stem cell |
| CN210237649U (en) * | 2019-05-29 | 2020-04-03 | 广东唯泰生物科技有限公司 | Stem cell culture robot |
-
2019
- 2019-05-29 CN CN201910457518.0A patent/CN110066733A/en active Pending
Patent Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1592779A (en) * | 2002-06-13 | 2005-03-09 | 奥林巴斯株式会社 | Culturing apparatus |
| JP2004305148A (en) * | 2003-04-09 | 2004-11-04 | Olympus Corp | Automatic culture apparatus |
| US20130210130A1 (en) * | 2010-04-21 | 2013-08-15 | Octane Biotech, Inc. | Automated cell culture system |
| CN102061260A (en) * | 2010-12-01 | 2011-05-18 | 汪华 | Medical automatic cell production device and production method thereof |
| US20140315303A1 (en) * | 2011-12-07 | 2014-10-23 | Cytover Inc. | Method and device for sample processing |
| WO2015023658A2 (en) * | 2013-08-12 | 2015-02-19 | Invivosciences Inc. | Automated cell culture system and method |
| CN108138130A (en) * | 2015-08-31 | 2018-06-08 | 爱平世股份有限公司 | The method of multipotential stem cell manufacture system and production induced multi-potent stem cell |
| CN205295360U (en) * | 2015-12-28 | 2016-06-08 | 江苏希瑞干细胞技术有限公司 | Navel cord automated processing device |
| WO2017221155A1 (en) * | 2016-06-20 | 2017-12-28 | Genesis Technologies Limited | Automated cell processing systems and methods |
| CN108048298A (en) * | 2017-12-01 | 2018-05-18 | 何加铭 | A kind of umbilical cord tissue mescenchymal stem cell separator and its control method |
| CN108102914A (en) * | 2017-12-27 | 2018-06-01 | 深圳北科赛动生物机器人有限公司 | Stem cell auto culturing system |
| CN210237649U (en) * | 2019-05-29 | 2020-04-03 | 广东唯泰生物科技有限公司 | Stem cell culture robot |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110908329A (en) * | 2019-12-23 | 2020-03-24 | 深圳赛动生物自动化有限公司 | Stem cell feeding and discharging bin control system and control method based on programmable controller |
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