CN110065695A - A kind of container containing ophthalmically acceptable product - Google Patents
A kind of container containing ophthalmically acceptable product Download PDFInfo
- Publication number
- CN110065695A CN110065695A CN201910466321.3A CN201910466321A CN110065695A CN 110065695 A CN110065695 A CN 110065695A CN 201910466321 A CN201910466321 A CN 201910466321A CN 110065695 A CN110065695 A CN 110065695A
- Authority
- CN
- China
- Prior art keywords
- container
- contact lens
- ophthalmically acceptable
- acceptable product
- polyhexamethylene guanide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D11/00—Containers having bodies formed by interconnecting or uniting two or more rigid, or substantially rigid, components made wholly or mainly of plastics material
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L23/10—Homopolymers or copolymers of propene
- C08L23/12—Polypropene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L25/00—Compositions of, homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring; Compositions of derivatives of such polymers
- C08L25/02—Homopolymers or copolymers of hydrocarbons
- C08L25/04—Homopolymers or copolymers of styrene
- C08L25/06—Polystyrene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L27/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers
- C08L27/02—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L27/04—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment containing chlorine atoms
- C08L27/06—Homopolymers or copolymers of vinyl chloride
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L55/00—Compositions of homopolymers or copolymers, obtained by polymerisation reactions only involving carbon-to-carbon unsaturated bonds, not provided for in groups C08L23/00 - C08L53/00
- C08L55/02—ABS [Acrylonitrile-Butadiene-Styrene] polymers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
- C08L67/02—Polyesters derived from dicarboxylic acids and dihydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L79/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen with or without oxygen or carbon only, not provided for in groups C08L61/00 - C08L77/00
Abstract
The present invention relates to a kind of containers for containing ophthalmically acceptable product, ophthalmically acceptable product can be with are as follows: contact lens, corneal contact lens nursing liquid, Lubricant Solution of Corneal Contact Lens and eye-drops preparations, container is made of the material comprising plastics, material also includes polyhexamethylene guanide, and polyhexamethylene guanide weight ratio is 0.1-20%.Since polyhexamethylene guanide (PHMG, CAS:57028-96-3) is added in the making material for containing ophthalmically acceptable product, so that saving container itself has biocidal property.Test proves that this preservation container can inhibit pathogenic bacteria to grow, and can greatly reduce the bacterium infection risk of contact lens wearer.
Description
Technical field
The present invention relates to a kind of containers for containing ophthalmically acceptable product.
Background technique
In order to inhibit bacterial growth, contact lens degerming in, needing to be stored in when not in use special conditioning liquid
And cleaning.Meanwhile conditioning liquid, lubricating fluid generate stimulation, destruction, injury etc., conditioning liquid, lubrication to eyeglass and cornea in order to prevent
Antipathogenic composition in liquid is all weaker, therefore has a large amount of bacterial depositions in the appearance for containing contact lense and its conditioning liquid, lubricating fluid
In device.The existing container for containing ophthalmically acceptable product such as contains the container of ophthalmically acceptable product contact lens, contains contact lens shield
The container of liquid is managed, the container of Lubricant Solution of Corneal Contact Lens is contained and contains the container of eye-drops preparations, container is generally all by plastics
Material composition, and the container for the splendid attire conditioning liquid and contact lens being made of plastic material is the main pollution of contact lens
Source.It is easy the ophthalmically acceptable product of pollution.
Summary of the invention
The present invention provides a kind of container for containing ophthalmically acceptable product, is easy pollution to solve the existing container for containing ophthalmically acceptable product
The technical issues of ophthalmically acceptable product.
In order to solve the above technical problems, the technical solution adopted by the present invention is that:
A kind of container containing ophthalmically acceptable product, the ophthalmically acceptable product can be with are as follows: contact lens, corneal contact lens nursing
Liquid, Lubricant Solution of Corneal Contact Lens and eye-drops preparations, the container are made of the material comprising plastics, which is characterized in that the material
Material also includes polyhexamethylene guanide, and the polyhexamethylene guanide weight ratio is 0.1-20%.
The plastics are selected from: polyethylene terephthalate or polyvinyl chloride or polypropylene or polystyrene or
Person's polystyrene or polymethyl methacrylate or poly- (chloro -1,4- phenylene sulphonyl -1,4- benzene) or polycarbonate.
The plastics are selected from: acrylonitrile, butadiene, styrol copolymer or acrylonitritrile-styrene resin or
Polyethylene.
The polyhexamethylene guanide weight ratio is 12-20%.
After using above-mentioned technical proposal, due to increasing the poly- of 0.1-20% weight ratio in the material that container is made
Hexa-methylene guanidine can greatly improve anti-microbial property after test proof increases the polyhexamethylene guanide of 0.1-20% weight ratio,
It solves the existing container for containing ophthalmically acceptable product and is easy the technical issues of polluting ophthalmically acceptable product.
Specific embodiment
A kind of container containing ophthalmically acceptable product, ophthalmically acceptable product can be with are as follows: contact lens, corneal contact lens nursing liquid, angle
Film Lens Lubricant and eye-drops preparations, container are made of the material comprising plastics, and material also includes polyhexamethylene guanide, and poly- six
Methylene guanidine weight ratio is 0.1-20%.Plastics may is that polyethylene terephthalate or polyvinyl chloride or polypropylene
Either polystyrene or polystyrene or acrylonitrile, butadiene, styrol copolymer or polymethyl methacrylate or
Person's acrylonitritrile-styrene resin or polyethylene or poly- (chloro -1,4- phenylene sulphonyl -1,4- benzene) or poly- carbonic acid
Ester, specific embodiment are as follows:
Embodiment one
A kind of contact lens and/or contact lense conditioning liquid and/or Lens Lubricant containing polyhexamethylene guanide and/or
The container of eye-drops preparations, this container are for saving, containing contact lens and/or contact lense conditioning liquid and/or contact lense
Lubricating fluid and/or eye-drops preparations.The container is the macromolecule material by containing polyethylene terephthalate (CAS:25038-59-9)
Material is process, while 0.1-20% (weight ratio) polyhexamethylene guanide is added, i.e. 1 gram of container body (lid without container and/or
Other attachmentes) in contain 1mg to 200mg polyhexamethylene guanide.
Embodiment two
A kind of contact lens and/or contact lense conditioning liquid and/or Lens Lubricant containing polyhexamethylene guanide and/or
The container of eye-drops preparations, this container are for saving, containing contact lens and/or contact lense conditioning liquid and/or contact lense
Lubricating fluid and/or eye-drops preparations.The container is formed by the processing of high molecular material containing polyvinyl chloride (CAS:9002-86-2),
While 0.1-20% (weight ratio) polyhexamethylene guanide is added, i.e. in 1 gram of container body (without the lid of container and/or other attachmentes)
Contain 1mg to 200mg polyhexamethylene guanide.
Embodiment three
A kind of contact lens and/or contact lense conditioning liquid and/or Lens Lubricant containing polyhexamethylene guanide and/or
The container of eye-drops preparations, this container are for saving, containing contact lens and/or contact lense conditioning liquid and/or contact lense
Lubricating fluid and/or eye-drops preparations.The container is formed by the processing of high molecular material containing polypropylene (CAS:9003-07-0), together
When 0.1-20% (weight ratio) polyhexamethylene guanide is added, i.e. contain in 1 gram of container body (without the lid of container and/or other attachmentes)
There is 1mg to 200mg polyhexamethylene guanide.
Example IV
A kind of contact lens and/or contact lense conditioning liquid and/or Lens Lubricant containing polyhexamethylene guanide and/or
The container of eye-drops preparations, this container are for saving, containing contact lens and/or contact lense conditioning liquid and/or contact lense
Lubricating fluid and/or eye-drops preparations.The container is formed by the processing of high molecular material containing polystyrene (CAS:9003-53-6),
While 0.1-20% (weight ratio) polyhexamethylene guanide is added, i.e. in 1 gram of container body (without the lid of container and/or other attachmentes)
Contain 1mg to 200mg polyhexamethylene guanide.
Embodiment five
A kind of contact lens and/or contact lense conditioning liquid and/or Lens Lubricant containing polyhexamethylene guanide and/or
The container of eye-drops preparations, this container are for saving, containing contact lens and/or contact lense conditioning liquid and/or contact lense
Lubricating fluid and/or eye-drops preparations.The container is by containing acrylonitrile, butadiene, the height of styrol copolymer (CAS:9003-56-9)
Molecular material is process, while 0.1-20% (weight ratio) polyhexamethylene guanide is added, i.e., 1 gram of container body is (without container
Lid and/or other attachmentes) in contain 1mg to 200mg polyhexamethylene guanide.
Embodiment six
A kind of contact lens and/or contact lense conditioning liquid and/or Lens Lubricant containing polyhexamethylene guanide and/or
The container of eye-drops preparations, this container are for saving, containing contact lens and/or contact lense conditioning liquid and/or contact lense
Lubricating fluid and/or eye-drops preparations.The container is added by the high molecular material containing polymethyl methacrylate (CAS:9003-21-8)
Work forms, while 0.1-20% (weight ratio) polyhexamethylene guanide is added, i.e. 1 gram of container body (without the lid of container and/or other
Attachment) in contain 1mg to 200mg polyhexamethylene guanide.
Embodiment seven
A kind of contact lens and/or contact lense conditioning liquid and/or Lens Lubricant containing polyhexamethylene guanide and/or
The container of eye-drops preparations, this container are for saving, containing contact lens and/or contact lense conditioning liquid and/or contact lense
Lubricating fluid and/or eye-drops preparations.The container is the macromolecule material by containing acrylonitritrile-styrene resin (CAS:9003-54-7)
Material is process, while 0.1-20% (weight ratio) polyhexamethylene guanide is added, i.e. 1 gram of container body (lid without container and/or
Other attachmentes) in contain 1mg to 200mg polyhexamethylene guanide.
Embodiment eight
A kind of contact lens and/or contact lense conditioning liquid and/or Lens Lubricant containing polyhexamethylene guanide and/or
The container of eye-drops preparations, this container are for saving, containing contact lens and/or contact lense conditioning liquid and/or contact lense
Lubricating fluid and/or eye-drops preparations.The container is formed by the processing of high molecular material containing polyethylene (CAS:9002-88-4), together
When 0.1-20% (weight ratio) polyhexamethylene guanide is added, i.e. contain in 1 gram of container body (without the lid of container and/or other attachmentes)
There is 1mg to 200mg polyhexamethylene guanide.
Embodiment nine
A kind of contact lens and/or contact lense conditioning liquid and/or Lens Lubricant containing polyhexamethylene guanide and/or
The container of eye-drops preparations, this container are for saving, containing contact lens and/or contact lense conditioning liquid and/or contact lense
Lubricating fluid and/or eye-drops preparations.The container is by containing poly- (chloro -1,4- phenylene sulphonyl -1,4- benzene) (CAS:25667-42-
9) processing of high molecular material forms, while 0.1-20% (weight ratio) polyhexamethylene guanide is added, i.e. 1 gram of container body (is free of
The lid of container and/or other attachmentes) in contain 1mg to 200mg polyhexamethylene guanide.
Embodiment ten
A kind of contact lens and/or contact lense conditioning liquid and/or Lens Lubricant containing polyhexamethylene guanide and/or
The container of eye-drops preparations, this container are for saving, containing contact lens and/or contact lense conditioning liquid and/or contact lense
Lubricating fluid and/or eye-drops preparations.The container is formed by the processing of high molecular material containing polycarbonate (CAS:25037-45-0),
While 0.1-20% (weight ratio) polyhexamethylene guanide is added, i.e. in 1 gram of container body (without the lid of container and/or other attachmentes)
Contain 1mg to 200mg polyhexamethylene guanide.
It is the antibacterial tests report of the container in above-described embodiment below
Antibacterial tests report summary sheet
Antibacterial tests are according to " Chinese Pharmacopoeia " 2015 editions-<inhibitory effect inspection technique>progress.
Antibiotic rate: using the plastics without PHMG as reference substance, using the plastics containing PHMG as test specimen.
Colony counts on antibiotic rate=1- test specimen on colony counts/reference substance
It is best to can be seen that effect when polyhexamethylene guanide weight ratio is preferably 12-20% for result from the experiment above.
The manufacturing method of vessel fabrication material
The manufacturing method of vessel fabrication material are as follows: injection molding will pass through note by dried polyhexamethylene guanide pellet
Molding machine is molded into mold, and antimicrobial plastic bottle can be waited until by cooling down to it.Set temperature is 215 DEG C in injection moulding process, note
Blow pressure is 60MPa, dwell time 10s.
The technology of the present invention is the production material in the container for containing contact lens and/or its conditioning liquid and/or its lubricating fluid
Polyhexamethylene guanide (PHMG, CAS:57028-96-3) is added in material, so that saving container itself has biocidal property.Test proves
This preservation container can inhibit pathogenic bacteria to grow, and can greatly reduce the bacterium infection risk of contact lens wearer.
Claims (4)
1. a kind of container for containing ophthalmically acceptable product, the ophthalmically acceptable product can be with are as follows: contact lens, corneal contact lens nursing liquid,
Lubricant Solution of Corneal Contact Lens and eye-drops preparations, the container are made of the material comprising plastics, which is characterized in that the material is also
Comprising polyhexamethylene guanide, the polyhexamethylene guanide weight ratio is 0.1-20%.
2. containing the container of ophthalmically acceptable product as described in claim 1, which is characterized in that the plastics are selected from: poly- to benzene two
Formic acid second diester or polyvinyl chloride or polypropylene or polystyrene or polystyrene or polymethyl methacrylate
Either poly- (chloro -1,4- phenylene sulphonyl -1,4- benzene) or polycarbonate.
3. containing the container of ophthalmically acceptable product as described in claim 1, which is characterized in that the plastics are selected from: acrylonitrile, fourth
Diene, styrol copolymer or acrylonitritrile-styrene resin or polyethylene.
4. containing the container of ophthalmically acceptable product as claimed in claim 2 or claim 3, which is characterized in that the polyhexamethylene guanide weight
Than for 12-20%.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910466321.3A CN110065695A (en) | 2019-05-31 | 2019-05-31 | A kind of container containing ophthalmically acceptable product |
| PCT/CN2019/095906 WO2020237790A1 (en) | 2019-05-31 | 2019-07-13 | Container for holding eye products |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910466321.3A CN110065695A (en) | 2019-05-31 | 2019-05-31 | A kind of container containing ophthalmically acceptable product |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110065695A true CN110065695A (en) | 2019-07-30 |
Family
ID=67372066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910466321.3A Pending CN110065695A (en) | 2019-05-31 | 2019-05-31 | A kind of container containing ophthalmically acceptable product |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN110065695A (en) |
| WO (1) | WO2020237790A1 (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1406836A (en) * | 2001-08-09 | 2003-04-02 | 庄臣及庄臣视力保护公司 | Invisual eyepiece package |
| CN2897875Y (en) * | 2006-03-03 | 2007-05-09 | 上海金莎纳米科技有限公司 | Sterilizing preservative box |
| CN102453273A (en) * | 2010-10-22 | 2012-05-16 | 中国石油化工股份有限公司 | Antibacterial master batch based on guanidinium polymer and preparation method thereof |
| CN105377250A (en) * | 2013-04-17 | 2016-03-02 | 蓝莓疗法有限公司 | Compositions and methods for combating antibacterial resistant bacteria |
| CN107652681A (en) * | 2017-10-12 | 2018-02-02 | 苏州创新达成塑胶模具有限公司 | A kind of high temperature resistant medical rigid plastic material |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5420217B2 (en) * | 2007-09-26 | 2014-02-19 | ディバーシー株式会社 | Disinfectant lubricant composition for conveyor and method of using the same |
| WO2013005215A2 (en) * | 2011-07-05 | 2013-01-10 | Strauss Water Ltd. | Phmg modified antimicrobial agents |
| CN103355908A (en) * | 2012-04-05 | 2013-10-23 | 北京尚迪妙瞳贸易有限公司 | Antimicrobial contact lens companion box |
| CN103497275B (en) * | 2013-08-09 | 2015-12-23 | 华北电力大学（保定） | A kind of antibacterial, antiviral guanidinesalt star polymer and its preparation method and application |
| KR20160037396A (en) * | 2014-09-27 | 2016-04-06 | 박종혁 | A storage in sterilizing |
| CN106512062A (en) * | 2016-12-14 | 2017-03-22 | 成都锦汇科技有限公司 | Multifunctional contact lenses care solution and preparation method thereof |
| CN109705455A (en) * | 2017-10-26 | 2019-05-03 | 中国石油化工股份有限公司 | A kind of antibacterial and mouldproof thermoplastic resin composition and preparation method thereof |
-
2019
- 2019-05-31 CN CN201910466321.3A patent/CN110065695A/en active Pending
- 2019-07-13 WO PCT/CN2019/095906 patent/WO2020237790A1/en active Application Filing
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1406836A (en) * | 2001-08-09 | 2003-04-02 | 庄臣及庄臣视力保护公司 | Invisual eyepiece package |
| CN2897875Y (en) * | 2006-03-03 | 2007-05-09 | 上海金莎纳米科技有限公司 | Sterilizing preservative box |
| CN102453273A (en) * | 2010-10-22 | 2012-05-16 | 中国石油化工股份有限公司 | Antibacterial master batch based on guanidinium polymer and preparation method thereof |
| CN105377250A (en) * | 2013-04-17 | 2016-03-02 | 蓝莓疗法有限公司 | Compositions and methods for combating antibacterial resistant bacteria |
| CN107652681A (en) * | 2017-10-12 | 2018-02-02 | 苏州创新达成塑胶模具有限公司 | A kind of high temperature resistant medical rigid plastic material |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020237790A1 (en) | 2020-12-03 |
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Application publication date: 20190730 |