CN110063771A - A kind of thrombus break catching apparatus - Google Patents

A kind of thrombus break catching apparatus Download PDF

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Publication number
CN110063771A
CN110063771A CN201910467436.4A CN201910467436A CN110063771A CN 110063771 A CN110063771 A CN 110063771A CN 201910467436 A CN201910467436 A CN 201910467436A CN 110063771 A CN110063771 A CN 110063771A
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CN
China
Prior art keywords
seal wire
thrombus
development code
catching apparatus
mesh basket
Prior art date
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Granted
Application number
CN201910467436.4A
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Chinese (zh)
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CN110063771B (en
Inventor
许永松
穆磊
唐航
陈飞
吴健
秦川
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BEIJING TAIJIEWEIYE TECHNOLOGY Co Ltd
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BEIJING TAIJIEWEIYE TECHNOLOGY Co Ltd
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Priority to CN201910467436.4A priority Critical patent/CN110063771B/en
Publication of CN110063771A publication Critical patent/CN110063771A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22038Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A61B2017/2217Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions single wire changing shape to a gripping configuration

Abstract

The invention belongs to interventional medical device technical fields, more particularly to a kind of thrombus break catching apparatus, it include: support component, the support component includes the first seal wire and the second seal wire, second seal wire is in hollow tubular, first seal wire is inserted into second seal wire, and second seal wire is stretched out at both ends;Mesh basket is woven, the braiding mesh basket is in the network management shape of an end closure, and the braiding mesh basket is sleeved on first seal wire, and both ends are fixed with first seal wire respectively;The sealing end of the braiding mesh basket is located at the distal end of first seal wire;Thrombus cuts skeleton, and the thrombus cutting skeleton is in network management shape, and is sleeved on first seal wire, and proximal end is fixedly connected with the distal end of second seal wire.The present invention provides one by the setting for the thrombus cutting skeleton that opposite can be slided and is capable of the embolus trapping region of dynamic regulation, to can not only arrest soft thrombus, can arrest the thrombus of hard, can also prevent the escape of emboli.

Description

A kind of thrombus break catching apparatus
Technical field
The invention belongs to interventional medical device technical fields, and in particular to a kind of thrombus break catching apparatus.
Background technique
Stroke is also known as " apoplexy ", " cerebrovascular accident ", is a kind of acute cerebrovascular diseases, is since cerebral vessels are broken suddenly It splits or causes one group of disease of brain tissue impairment, including ischemic and bleeding because blood is caused to cannot flow into brain for angiemphraxis Property stroke.Stroke is the major disease for seriously threatening China human mortality health and hindering socio-economic development, wherein acute ischemic The 70% of cerebral apoplexy (AIS) Zhan Suoyou stroke, new AIS patient is more than 2,000,000 every year in China.AIS treatment critical period be Acute stage, intravenous thrombolysis can improve patient's prognosis, but not good enough to vessel occlusion therapeutic effect.With endovascular technology and The development of material, positive test, which demonstrates endovascular treatment, can significantly improve the prognosis of intracranial vessel occlusion patient, reduce and cause Residual rate and the death rate, various countries' guide updates in succession as a result, takes bolt as the head of acute preceding circulation vessel occlusion patient machinery Therapeutic modality is wanted, and gives highest level recommendation.The medical system of national governments all is being endeavoured to improve AIS first aid procedure, determines Specifications promote the clinical expansion of this revolutionary technology.
A kind of for capturing the device of thrombus, the device mesh basket portion is referred in United States Patent (USP) US2006/0030878 A1 Divide and woven using the metal composite wire that can develop, structure is relatively simple, and this device is applied in general in stent procedure mistake Cheng Zhong is placed on blood vessel distal end progress static state and arrests the thrombus generated in stenting, is difficult to be directly used in acute apoplexy machinery Take the treatment of bolt.A kind of thrombectomy device and preparation method thereof is disclosed in 101912289 A of Chinese patent CN, core is used It is woven in the mesh basket part of thrombectomby using metal composite wire, although having preferable radial support power, it is in blood Ability is arrested with certain for new soft thrombus in pipe, and or atherosclerotic plaque longer for disease time is formed Hard thrombus almost defy capture.A kind of novel mechanical is disclosed in United States Patent (USP) US10258358 B2 takes thrombus device, it should Device is formed using integrated laser engraving, and the proximal end of break catching apparatus has standoff feature, can be embedded in soft thrombus, Interlude is provided with 2 symmetrical embolus fall regions, distally has the carrier unit of closure, which takes compared to traditional machinery Thrombus bracket (such as the Trevo bracket of Stryker company, Solitarie bracket of ev3 company etc.), biggest advantage is In addition to soft embolus can be arrested, additionally it is possible to the thrombus of hard and success rate with higher are arrested, however existing for it not Foot place has two o'clock: (1) carrier unit of distal end closure still has very big mesh, is difficult to ensure that medium and small embolus is not escaped in art Ease, causes patients surgery prognosis undesirable;(2) the embolus trapping region of break catching apparatus interlude setting is fixed, big when encountering The hard thrombus of block defies capture success.
Therefore, against the above deficiency, present invention urgent need provides a kind of thrombus break catching apparatus, to solve the above problems.
Summary of the invention
The purpose of the present invention is to provide a kind of thrombus break catching apparatus, with solve in the prior art thrombus acquisition equipment not The problem of thrombus captures can once be completed.
Thrombus break catching apparatus provided by the invention, comprising: support component, the support component include the first seal wire and second Seal wire;Second seal wire is in hollow tubular;First seal wire is inserted into second seal wire, and described in both ends stretch out Second seal wire;Mesh basket is woven, the braiding mesh basket is in the tubulose of an end closure, and tube wall is equipped with mesh;The braiding mesh basket Both ends fixed respectively with first seal wire, and sealing end is located at the distal end of first seal wire;Thrombus cuts skeleton, described Thrombus cuts skeleton in a tubular form, and tube wall is equipped with mesh;The thrombus cutting skeleton is sleeved on first seal wire, and close End is fixedly connected with the distal end of second seal wire.
Thrombus break catching apparatus as described above, further preferably, the proximal end of the braiding mesh basket are equipped with the first cambered surface, institute The distal end for stating thrombus cutting skeleton is equipped with the second cambered surface, and first cambered surface and second cambered surface are corresponding in bowl-shape.
Thrombus break catching apparatus as described above, further preferably, further include the first development code is carved, the second development code is carved, Third is developed code quarter and the 4th development code quarter;The first development code is carved and the second development code quarter is separately fixed at the volume The both ends of knitmesh basket, and be fixedly connected with first seal wire;The third development code is carved and the 4th development code is carved in hollow Tubular is separately fixed at the both ends of the thrombus cutting skeleton, and third development code is carved movable set and led described first On silk, the 4th development code carves the distal end for being fixedly set in second seal wire.
Thrombus break catching apparatus as described above further includes further preferably spacer spring, and the spacer spring is fixed to be connected It connects on first seal wire, and the spacer spring is located at the second development code and carves between third development code quarter.
Thrombus break catching apparatus as described above further includes further preferably anchoring pipe, and the anchoring pipe sleeve dress is fixed on On first seal wire;The anchoring pipe is located at the inside of thrombus cutting skeleton with the link position of first seal wire, And the outer diameter of the anchoring pipe is greater than the internal diameter that third development code is carved, and is suitable for carving limit to third development code.
Alternatively, thrombus break catching apparatus as described above, further preferably, the anchoring pipe and first seal wire Link position be located at the proximal end of first seal wire, and the outer diameter of the anchoring pipe is greater than the internal diameter of second seal wire, fits It is limited in second seal wire.
Thrombus break catching apparatus as described above further includes further preferably head end spring, and the head end spring pocket is mounted in The distal end of first seal wire, and both ends are fixedly connected with first seal wire.
Thrombus break catching apparatus as described above, further preferably, the distal end of the braiding mesh basket are equipped with the first inclined-plane;Institute The lateral projection of braiding mesh basket is stated in irregular trapezoidal shape, two stringcourses of the lateral projection are first inclined-plane and described first The projection line of cambered surface, lower baseline are overlapped with first seal wire.
Thrombus break catching apparatus as described above, further preferably, the tube wall of the thrombus cutting skeleton includes multiple cuts Unit is cut, the cutter unit is the closed loop or partial open loop around the tube wall;The closed loop or partial open loop in sine wave or Cosine is wavy;The adjacent closed loop or partial open loop constitute the mesh of tube wall.
Thrombus break catching apparatus as described above, further preferably, first guidewire proximal is additionally provided with the first mark point With the second mark point, first mark point and the setting of second mark point interval, suitable for assisting determining for second seal wire Position.
The present invention has the advantage that compared with prior art
In the application, the braiding mesh basket of an end closure is suitable for catching the thrombus that specification is greater than mesh grid net hole, institute Thrombus cutting skeleton is stated to be suitable for blocking big specification thrombus by its own;It is empty that the support component is then used to convey and provide installation Between, wherein the combined complete of the first seal wire and the second seal wire setting be suitable for make respectively with first seal wire, second seal wire It opposite can be slided between the braiding mesh basket being fixedly mounted and thrombus cutting skeleton, so that this structure is weaving The embolus trapping region for capableing of dynamic regulation is additionally provided except mesh basket and thrombus cutting skeleton, so that the present embodiment institute Disclosed thrombus break catching apparatus has according to thrombus in addition to that can arrest the new soft thrombus of AIS, can also pass through dynamic regulation The size maximum magnitude of embolus trapping region arrests the thrombus of hard, and the braiding mesh basket of distal section is being caught due to sealing distal end While massive, the escape of emboli can also be prevented.
Detailed description of the invention
Fig. 1 is the first structural schematic diagram of thrombus break catching apparatus of the invention;
Fig. 2 is second of structural schematic diagram of thrombus break catching apparatus of the invention;
Fig. 3 is that acute ischemic cerebral apoplexy newly sends out soft thrombus schematic diagram;
Fig. 4 is the intravascular conveying schematic diagram of thrombus break catching apparatus of the invention;
Fig. 5 takes thrombus process schematic for thrombus break catching apparatus of the invention;
Fig. 6 is the partially recycled schematic diagram of thrombus of thrombus break catching apparatus of the invention;
Fig. 7 is that the thrombus of thrombus break catching apparatus of the invention recycles schematic diagram completely;
Fig. 8 is acute ischemic cerebral apoplexy hard thrombus schematic diagram;
Fig. 9 is the intravascular conveying schematic diagram of thrombus break catching apparatus of the invention;
Figure 10 takes thrombus process schematic for thrombus break catching apparatus of the invention;
Figure 11 is that the thrombus of thrombus break catching apparatus of the invention recycles schematic diagram completely.
Description of symbols:
The first seal wire of 1-, the second seal wire of 2-, 3- weave mesh basket, and 4- thrombus cuts skeleton, the first cambered surface of 5-, the second arc of 6- Face, 7- first develop code quarter, and 8- second develops code quarter, and 9- third development code is carved, and the development code of 10- the 4th is carved, 11- spacer spring, 12- anchoring pipe, 13- head end spring, the first mark point of 14-, the second mark point of 15-;
20- blood vessel, 21- microtubular, 22- intermediate conductor, the soft thrombus of 49-, 50- microthrombus, 51- hard thrombus.
Specific embodiment
Technical solution of the present invention is clearly and completely described below in conjunction with attached drawing, it is clear that described implementation Example is a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ordinary skill Personnel's every other embodiment obtained without making creative work, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that term " center ", "upper", "lower", "left", "right", "vertical", The orientation or positional relationship of the instructions such as "horizontal", "inner", "outside" be based on the orientation or positional relationship shown in the drawings, merely to Convenient for description the present invention and simplify description, rather than the device or element of indication or suggestion meaning must have a particular orientation, It is constructed and operated in a specific orientation, therefore is not considered as limiting the invention.In addition, term " first ", " second ", " third " is used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance.
Thrombus break catching apparatus disclosed in the present application is mainly used for interventional therapy, opening of the medical worker from blood vessel when treatment Thrombus break catching apparatus is inserted into blood vessel by place along blood flow direction take bolt after withdraw from, therefore, close to hand-held one end in the application It is distal end far from hand-held one end for proximal end, being reflected in Fig. 1-11 is then that left end is distally, and right end is proximal end.Picture 1-4 It is shown, thrombus break catching apparatus disclosed in the present embodiment, comprising: support component, the support component include the first seal wire 1 and second Seal wire 2;Second seal wire 2 is in hollow tubular, and first seal wire 1 is inserted into second seal wire 2, and both ends are stretched out Second seal wire 2;Mesh basket 3 is woven, the braiding mesh basket 3 is in the tubulose of an end closure, and tube wall is equipped with mesh;The volume Knitmesh basket 3 is sleeved on first seal wire 1, and both ends are fixed with first seal wire 1 respectively;The envelope of the braiding mesh basket 3 Mouth end is located at the distal end of first seal wire 1;Thrombus cuts skeleton 4, and the thrombus cutting skeleton 4 in a tubular form, and is set on tube wall There is mesh;The thrombus cutting skeleton is sleeved on first seal wire 1, and proximal end and the distal end of second seal wire 2 are fixed Connection.
In above structure, the braiding mesh basket 3 of an end closure is suitable for catching the blood that specification is greater than braiding 3 mesh of mesh basket Bolt, the thrombus cutting skeleton 4 are suitable for blocking big specification thrombus by its own;The support component is then used to convey and provide Installation space, wherein the combined complete of the first seal wire 1 and the second seal wire 2 setting be suitable for make respectively with first seal wire 1, institute Stating opposite can slide between the braiding mesh basket 3 of the second seal wire 2 fixed installation and thrombus cutting skeleton 4, and then make It obtains this structure and additionally provides the embolus trapping region for capableing of dynamic regulation except braiding mesh basket 3 and thrombus cutting skeleton 4, from And thrombus break catching apparatus disclosed in the present embodiment is had according to thrombus in addition to that can arrest the new soft thrombus 49 of AIS, Can also arrest hard thrombus by the size maximum magnitude of dynamic regulation embolus trapping region, and the braiding mesh basket 3 of distal end by It is sealed in distal end, while catching massive, the escape of small thrombus can also be prevented.
Further, in the thrombus break catching apparatus disclosed in above-described embodiment, the proximal end of the braiding mesh basket 3 is equipped with the One cambered surface 5, the distal end of the thrombus cutting skeleton 4 are equipped with the second cambered surface 6, first cambered surface 5 and second cambered surface 6 combination In bowl-shape.By the shape of optimization embolus trapping region in the present embodiment, make it in bowl-shape or arc-shaped, so with hard thrombus 51 Shape adaptation, on the one hand facilitate hard thrombus 51 to fall into embolus trapping region, while also facilitating the clamping and conveying in later period.
Further, in the thrombus break catching apparatus disclosed in above-described embodiment, the distal end of the braiding mesh basket 3 is equipped with the One inclined-plane;The lateral projection of the braiding mesh basket 3 is in irregular trapezoidal shape, and two stringcourses of the lateral projection are first inclined-plane With the projection line of first cambered surface 5, lower baseline is overlapped with first seal wire 1.Further, disclosed in above-described embodiment Thrombus break catching apparatus in, the tube wall of thrombus cutting skeleton 4 includes multiple cutter units, and the cutter unit is around described The closed loop or partial open loop of tube wall;The closed loop or partial open loop are wavy in sine wave or cosine;The adjacent closed loop or office The mesh of portion's open loop composition tube wall.Preferably, the thrombus cuts the also trapezoidal setting of skeleton 4, wherein lower baseline and described the One seal wire 1 is overlapped.In the present embodiment, trapezoidal be suitable for convenient for institute is arranged in the braiding mesh basket 3 and thrombus cutting skeleton 4 It states braiding mesh basket 3 and thrombus cutting skeleton 4 folds deformation, and then facilitate withdrawing from for thrombus break catching apparatus.
It further, further include that the first development code carves 7, second in the thrombus break catching apparatus disclosed in above-described embodiment The code that develops carves 8, third development code quarter 9 and the 4th development code carves 10;The first development code carves 7 and the second development code quarter 8 The both ends of the braiding mesh basket 3 are separately fixed at, and are fixedly connected with first seal wire 1;The third development code carves 9 Hes It is in hollow tubular that 4th development code, which carves 10, is separately fixed at the both ends of the thrombus cutting skeleton 4, and third development code is carved For 9 movable sets on first seal wire 1, the 4th development code carves 10 distal ends for being fixedly set in second seal wire 2.This In embodiment, it is described first development code carve 7, second development code carve 8, third development code carve 9 and the 4th development code carve 10 setting It is mainly used for realizing that the braiding mesh basket 3, thrombus cutting skeleton 4 and first seal wire 1, second seal wire 2 are consolidated Fixed connection, while being also used to auxiliary positioning.The first development code carved for the 7, second development code quarter 8, third development code carves 9 and the 4th Development code carves 10 and conventional platinumiridio is selected to be made, suitable for developing over the course for the treatment of.
It further, further include spacer spring 11, the isolation in the thrombus break catching apparatus disclosed in above-described embodiment The fixation of spring 11 is set on first seal wire 1, and the spacer spring 11 is located at the second development code and carves 8 and described the Three development codes are carved between 9.The spacer spring 11 is fixed on first seal wire, and is located at the second development code and is carved 8 Hes The third development code is carved between 9, suitable for separating the braiding mesh basket 3 and thrombus cutting skeleton 4, and then is formed adjustable The bottom section of embolus trapping region, while the positioning that there is spacer spring developability can also increase embolus trapping region original state. Preferably, the length of spacer spring 11 described in the present embodiment is 2-10mm, is closed using the platinum tungsten of string diameter range 0.02-0.05mm Gold or platinumiridio silk are entwined, and the screw pitch of the spacer spring 11 is equal with string diameter, and both ends and the first seal wire 1 pass through soldering Or the method for bonding is respectively formed the solder joint or adhesive spots of taper.
It further, further include anchoring pipe 12 in the thrombus break catching apparatus disclosed in above-described embodiment, the anchoring pipe 12 suits are fixed on first seal wire 1;The link position of the anchoring pipe 12 and first seal wire is located at the thrombus The inside of skeleton 4 is cut, and the outer diameter of the anchoring pipe 12 is greater than the internal diameter that third development code carves 9, is suitable for described the Three development codes carve 9 limits;Or the anchoring pipe 12 and the link position of first seal wire are located at the close of first seal wire 1 End, and the outer diameter of the anchoring pipe 12 is greater than the internal diameter of second seal wire 2, is suitable for limiting second seal wire 2.This implementation Example discloses the installation site of two kinds of anchoring pipes 12, and structure difference is as shown in Figs. 1-2, but the institute of two kinds of mounting structures The function of stating anchoring pipe 12 is identical, i.e., carves 9 moving displacement or by limiting described second by limiting the third development code The moving displacement of seal wire 2 limits the slide displacement of thrombus cutting skeleton 4.In actual use, the anchoring pipe 12 is suitable for The sliding distance of thrombus cutting skeleton 4 is limited within 20mm.
It further, further include head end spring 13, the head end in the thrombus break catching apparatus disclosed in above-described embodiment Spring 13 is sleeved on the distal end of first seal wire 1, and both ends are fixedly connected with first seal wire 1.In the present embodiment, institute It is Nian Jie with first seal wire 1 by ultra-violet curing agent to state head end spring 13, and the bonding point of distal end is in shape for hat, and then reduction pair The bonding electricity of the damage of blood vessel 20, proximal end is tapered.The present embodiment strengthens described the by the way that 13 one side of head end spring is arranged The distal end intensity of one seal wire 1 reduces its probability deformed in blood vessel 20, on the other hand then for reducing the damage to blood vessel 20 Wound.
Further, in the thrombus break catching apparatus disclosed in above-described embodiment, 1 proximal end of the first seal wire is additionally provided with One mark point 14 and the second mark point 15, first mark point 14 and the setting of second mark point 15 interval, are suitable for auxiliary The positioning of second seal wire 2.The setting of first mark point 14 and second mark point 15 is suitable to facilitate to observe, in turn Auxiliary operation person carries out positioning operation.
Preferably, in above structure, the braiding mesh basket 3 is woven by metal composite wire, material preferred nickel/titanium alloy Silk and platinum alloy silk, wherein weave silk material based on nitinol alloy wire, and its role is to provide preferable shape for braiding mesh basket 3 Memory function, platinum alloy silk are development silk material, provide preferable development locating effect in art for mesh basket entire body.Wherein, described The metal composite wire of the braiding preferred string diameter 0.02-0.05mm of mesh basket 3 weaves, and when braiding, and the braiding mesh basket 3 is used to be compiled The total radical range for knitting silk is 36-64 root, and wherein the radical range of platinum alloy silk is set as 2-8 root.
As shown in Figs. 1-2, the braiding mesh basket 3 is in network management shape, suitable for can effectively be bonded after opening in blood vessel 20 Blood vessel 20, it is preferred that its side projection shape is irregular trapezoidal, the figure that ABCD is enclosed in Fig. 1-2, wherein trapezoidal Upper bottom AB, CD are respectively the side projection line at the top and bottom of network management, and trapezoidal stringcourse AC, BD are first inclined-plane and institute The side projection line of the first cambered surface 5 is stated, and the face where stringcourse AC is sealing state, the face where stringcourse BD is open state. CD sections of length is 8-25mm in the braiding mesh basket 3, and AB sections and CD Length Ratio are about 0.15-0.40;The braiding mesh basket 3 Diameter be 3-6mm.Preferably, the braiding mesh basket 3 changes in gradient in AC sections of aperture, and 50-350 microns of average pore size, AB sections are to reach higher radial support power, and average pore size scope is 30-300 microns.The first development code carves 7 and described the Two development codes are carved 8 and are respectively fixedly connected at CD sections of both ends, then connect with first seal wire 1, are adapted to the braiding Mesh basket 3 and first seal wire 1.
The thrombus cutting skeleton 4 is made using the Nitinol pipe through laser engraving and aftertreatment technology, thrombus The cell of cutting skeleton 4 has the function of thrombus cutting, and entire thrombus cutting 4 side projection of skeleton is in irregular isosceles ladder Shape, if EFGH is enclosed trapezoidal in Fig. 1-2, wherein EH sections of length range is 10-40mm, FG sections with EH sections of length ratio about For 0.20-0.80.It is 3-6mm for making the diameter of Nitinol pipe of thrombus cutting skeleton 4 in the present embodiment.
The third development code for being in the form of a column structure carves 9 and the 4th development code quarter 10 is connected to the thrombus and cuts 4EH sections of skeleton of both ends are cut, while third development code carves 9 movable sets on first seal wire 1, the 4th development Code carves 10 distal ends for being fixedly set in second seal wire 2, suitable for thrombus cutting skeleton 4 is slidably mounted on described first On seal wire 1, and its sliding can be adjusted by the second seal wire 2.
In the present embodiment, the adjustable embolus constituted between the thrombus cutting skeleton 4 and the braiding mesh basket 3 is captured The side projection in area is circular arc area formed by BDEF, and adjustable embolus trapping region consists of three parts, i.e. the first cambered surface 5, the Two cambered surfaces 6 and the first seal wire of DE section 1, side projection shape are in bowl-type or arc-shaped.
In the present embodiment, first seal wire 1 is made of stainless steel or nickel-titanium alloy material, is multistage taper design, Diameter changes between 0.05-0.30mm as needed;The overall length of the seal wire of first seal wire 1 is 180-300cm, and proximal end is about 160-280cm sections have PTFE coating.
In the present embodiment, second seal wire 2 is hollow stainless steel tube, diameter 0.40-0.65mm, overall length 140- 190cm is designed using hypo screwed pipe at the position of distal end 10-30cm, for increasing the flexibility of conveying lever distal end, distal end It is fixed as one by way of laser welding or bonding with the 4th yard of quarter.
Further, the processing method that a kind of thrombus break catching apparatus of specific size is also disclosed in the present embodiment:
(1) network management that 36 metal composite wires are woven into diameter 4mm on accurate braider is chosen, wherein platinumiridio is aobvious The radical of shadow silk is 4, and remaining is nitinol alloy wire, and all metal string diameter ranges are 0.03mm, and woven network management is 500 Vacuum heat treatment carries out shaping at DEG C, is then locked on the mold that side projection is approximate trapezoid, heat treatment is fixed again After type, braiding mesh basket 3 is obtained, then the both ends of the braiding mesh basket 3 are individually fixed in the first development code quarter 7 and the second development code It carves in 8;
(2) the Nitinol pipe of diameter 4mm is carved using femtosecond laser cutting machine, at 550 DEG C after the completion of engraving Lower carry out heat treatment shaping, then obtains the skeleton of surface-brightening by processes such as pickling, chemical polishings, obtains thrombus cutting bone Frame 4, then the both ends of thrombus cutting skeleton 4 were individually fixed in third development code quarter 9 and the 4th development code quarter 10;
(3) using accurate torsion machine, fine and close head end spring 13 is made of the platinum-tungsten alloys filament winding of 0.04mm, then uses knife Piece fixed length is 5mm, then fine and close spacer spring 11 is made of the platinum-tungsten alloys filament winding of 0.05mm, is 5mm with blade fixed length;
(4) thrombus is cut into skeleton 4, spacer spring 11, braiding mesh basket 3 and is successively distally placed on overall length 210cm, diameter certainly 0.08-0.28mm, and on the first seal wire 1 with proximal marker point sum, the first development code is then carved 7 by the method for soldering Carve and 8 fixed with the first seal wire 1 respectively with the second development code, then with the method for soldering by spacer spring 11 and the first seal wire 1 into Row is fixed, and two pads are formed;
(5) the anchoring pipe 12 that length is 1.5mm is socketed on first seal wire 1 by its barbed portion, and be located at Thrombus is cut into skeleton 4 and the distance developed apart from third is 10mm, and is fixed by way of soldering with the first seal wire 1;
(6) distal end of the first seal wire 1 is penetrated to the inner cavity of head end spring 13, the both ends of head end spring 13 and the first seal wire 1 It is fixed by ultraviolet cured adhesive, and distal bond point is in ball cap shape, proximal bond point is tapered;
(7) be 160cm by overall length, diameter be distal end 20cm the section of the second seal wire 2 of 0.50mm use laser cutting machine into Row screw thread process, then by the second seal wire 2 after processing from being distally placed on the first seal wire 1, tip passes through laser welding mode 10 to be carved with the 4th development code to be fixed as together, the distal threads section of the second seal wire 2 is coated using ultra-thin transparent heat-shrink tube, To obtain the thrombus break catching apparatus with specific size.
Further, in conjunction with attached drawing 3-11, the present embodiment also discloses the specifically used method of above-mentioned thrombus break catching apparatus:
S1: as shown in figures 3 and 8, the situation of thrombus in blood vessel 20 is detected, and is ready work;
S2: as shown in figures 4 and 9, thrombus capture device is about 0.027 inch through internal diameter by the proximal end of hand-held first seal wire Microtubular 21 diseased region of blood vessel is transported to from Jie inlet, and braiding mesh basket 3 is allowed to be located at the distal end of thrombus;
S3: as shown in figure 5 and figure 10, withdrawing microtubular 21, and thrombus capture device is allowed to carry out release in situ, when thrombus is soft When matter thrombus 49, thrombus cutting skeleton 4 can be easy self-expanding in blood vessel 20 and open and cut soft thrombus 49 insertion thrombus In the cutter unit of skeleton 4, small microthrombus 50 may be generated in the process and flows to 20 distal end of blood vessel;When thrombus is hard Matter thrombus 51 can not open completely after thrombus cutting 4 release in situ of skeleton and be embedded in thrombus, at this time by withdrawing second Seal wire makes thrombus trapping region further expansion, until bulk hard thrombus 51 is fallen completely in the circular arc area of thrombus trapping region; When operating the second seal wire, auxiliary positioning can be carried out according to the first mark point and the second mark point, and judge thrombus trapping region most Big region;
S4: as shown in fig. 6, continuing to withdraw the second seal wire 2, first allowing thrombus cutting skeleton 4 to be recovered in intermediate conductor 22, The emboli that this process generates all is braided mesh basket 3 and captures and form more agglomerate thrombus, and hard thrombus 51 is then by part Or it is fished out into braiding mesh basket 3 completely;
S5: as seen in figs. 7 and 11, continue to withdraw the second seal wire 2, the braiding mesh basket 3 for capturing thrombus is allowed to take in centre In conduit 22, thrombus capture device and intermediate conductor 22 are finally withdrawn from into human body as a whole.
One kind that the application provides is used for the thrombus break catching apparatus of acute ischemic cerebral apoplexy (AIS) treatment, due to setting Embolus trapping region (B-D-E-F circular arc area) is adjusted in dynamic, can arrest AIS new soft thrombus 49 and maximum model The thrombus for arresting hard is enclosed, while the braiding mesh basket 3 of distal end is catching massive due to designing with thinner metal mesh opening While, the escape of emboli can be prevented, braiding mesh basket 3 itself has soft spy due to forming using weaving filaments Sign, lower to the damage of blood vessel 20 of more distal end, entire surgical procedure uses inside and outside double seal wires slidably operating technology, easy to operate It controllably, is the key point of the present embodiment technology above.
Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations;To the greatest extent Pipe present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: its according to So be possible to modify the technical solutions described in the foregoing embodiments, or to some or all of the technical features into Row equivalent replacement;And these are modified or replaceed, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution The range of scheme.

Claims (10)

1. a kind of thrombus break catching apparatus characterized by comprising
Support component, the support component include the first seal wire and the second seal wire;Second seal wire is in hollow tubular;Described One seal wire is inserted into second seal wire, and second seal wire is stretched out at both ends;
Mesh basket is woven, the braiding mesh basket is in the tubulose of an end closure, and tube wall is equipped with mesh;The both ends of the braiding mesh basket It is fixed respectively with first seal wire, and sealing end is located at the distal end of first seal wire;
Thrombus cuts skeleton, and the thrombus cuts skeleton in a tubular form, and tube wall is equipped with mesh;The thrombus cutting skeleton suit On first seal wire, and proximal end is fixedly connected with the distal end of second seal wire.
2. thrombus break catching apparatus according to claim 1, which is characterized in that the proximal end of the braiding mesh basket is equipped with the first arc Face, the distal end of the thrombus cutting skeleton are equipped with the second cambered surface, and first cambered surface and second cambered surface are corresponding in bowl-shape.
3. thrombus break catching apparatus according to claim 2, which is characterized in that further include that the first development code is carved, second develops Code is carved, third development code is carved and the 4th development code is carved;
It is described first development code carve and it is described second development code carve is separately fixed at it is described braiding mesh basket both ends, and with it is described First seal wire is fixedly connected;
The third development code is carved and the 4th development code quarter was in hollow tubular, is separately fixed at the two of the thrombus cutting skeleton End, and third development code carves movable set on first seal wire, the 4th development code quarter is fixedly set in described The distal end of second seal wire.
4. thrombus break catching apparatus according to claim 3, which is characterized in that it further include spacer spring, the spacer spring It is fixedly connected on first seal wire, and the spacer spring is located at the second development code quarter and third development code is carved Between.
5. thrombus break catching apparatus according to claim 4, which is characterized in that it further include anchoring pipe, the anchoring pipe sleeve dress It is fixed on first seal wire;
The anchoring pipe is located at the inside of thrombus cutting skeleton with the link position of first seal wire, and the anchoring is managed Outer diameter be greater than the third development code carve internal diameter, be suitable for the third development code carve limit.
6. thrombus break catching apparatus according to claim 4, which is characterized in that it further include anchoring pipe, the anchoring pipe sleeve dress It is fixed on first seal wire;The link position of the anchoring pipe and first seal wire is located at the close of first seal wire End, and the outer diameter of the anchoring pipe is greater than the internal diameter of second seal wire, is suitable for limiting second seal wire.
7. the thrombus break catching apparatus according to any one of claim 5 or 6, which is characterized in that further include head end spring, institute The distal end that head end spring pocket is mounted in first seal wire is stated, and both ends are fixedly connected with first seal wire.
8. thrombus break catching apparatus according to claim 7, which is characterized in that the distal end of the braiding mesh basket is equipped with first tiltedly Face;The lateral projection of the braiding mesh basket is in irregular trapezoidal shape, and two stringcourses of the lateral projection are first inclined-plane and institute The projection line of the first cambered surface is stated, lower baseline is overlapped with first seal wire.
9. thrombus break catching apparatus according to claim 8, which is characterized in that the tube wall of the thrombus cutting skeleton includes more A cutter unit, the cutter unit are the closed loop or partial open loop around the tube wall;The closed loop or partial open loop are in sine Wave or cosine are wavy;The adjacent closed loop or partial open loop constitute the mesh of tube wall.
10. thrombus break catching apparatus according to claim 9, which is characterized in that first guidewire proximal is additionally provided with first Mark point and the second mark point, first mark point and the setting of second mark point interval, lead suitable for auxiliary described second The positioning of silk.
CN201910467436.4A 2019-05-31 2019-05-31 Thrombus capturing device Active CN110063771B (en)

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