CN110051556A - A kind of liniment and its manufacturing method for protecting nail - Google Patents

A kind of liniment and its manufacturing method for protecting nail Download PDF

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Publication number
CN110051556A
CN110051556A CN201910468355.6A CN201910468355A CN110051556A CN 110051556 A CN110051556 A CN 110051556A CN 201910468355 A CN201910468355 A CN 201910468355A CN 110051556 A CN110051556 A CN 110051556A
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China
Prior art keywords
mass
nail
liniment
ethyl alcohol
adsorbent
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Pending
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CN201910468355.6A
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Chinese (zh)
Inventor
刘小立
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Individual
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Individual
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Priority to CN201910468355.6A priority Critical patent/CN110051556A/en
Publication of CN110051556A publication Critical patent/CN110051556A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • A61K8/416Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q3/00Manicure or pedicure preparations
    • A61Q3/02Nail coatings

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A kind of liniment for protecting nail; it includes bitter principle 0.0014%-0.003% by mass; adsorbent 0.08%-1% by mass; promote the substance 0.1%-1% by mass of nail metabolism growth; remaining is solvent; wherein the bitter principle is Denatonium Benzoate; the adsorbent is acrylic acid (ester) class/Diacetone Acrylamide AMP salt; the substance for promoting nail metabolism growth is Keratin amino acids class; the solvent is made of water and ethyl alcohol, and it is 0.6%-1% that wherein the content of ethyl alcohol accounts for the ratio of liniment by mass.Liniment application method of the invention is simple, and one liang of drop need to be only dripped on finger nail and is directly smeared, or is poured into sub-bottling, using hairbrush brush on nail, then can play the role of within natural air drying 2-3 minutes protecting nail.The invention further relates to a kind of methods for manufacturing above-mentioned liniment.

Description

A kind of liniment and its manufacturing method for protecting nail
Technical field
The present invention relates to a kind of liniments and its manufacturing method for protecting nail, and it is suitable for having the nail habit that bites Crowd.
Background technique
In daily life, the people of fingernail biting often can be appreciated that.Fingernail biting is also referred to as fingernail biting disease or nail-biting, refers to repeatedly The behavior of fingernail biting.Childhood that fingernail biting is a kind of common bad habit, be more common in 3~6 years old children, men and women can fall ill. Most children fingernail biting behavior with age can die away, and a small number of bigots can continue until adult.
Following a few classes can be divided by this phenomenon reason occur substantially:
One, spiritual reason.Relationship Comparison is big among the environment of spirit compared with fingernail biting is usually in people, such as child is prominent A new environment so is entered, will cause the overstretched of child at this time, and for the pressure of keeping tensions down, child can not be certainly The fingernail biting of feel.Change child when such as child starts going to a nursery, enters a school in rhythm of life and be particularly easy to anxiety occur, also holds when sick Easily induce this disease.
Two, imitation factor causes.The part children nail that bites is formed due to imitating other people.Child has very strong Study ability to model will consciously think that such movement has very much when child sees the movement of other child's fingernail bitings Attraction will imitate automatically, more than such movement, will naturally become habit.
Three, personality reason.Have the characteristics that the children of the personality such as introversion, sensitivity, anxiety quality are easy to suffer from this disease.
Four, nutritional deficiency causes.If child has the habit of fingernail biting, may is that in default of corresponding nutrient , clinical data proves, body lacks zinc, then the probability of the fingernail biting of children can be much larger than normal children, in addition such as Fruit also lacks specific protein, also will increase the probability of fingernail biting.
Child shows as fingernail biting repeatedly.Less serious case only bites nail, and serious person can sting each nail bad, or even stings and badly refers to Skin around first, a small number of children also sting toenail.Among Children is often accompanied by other behavioral problems, such as sleep disturbance, more dynamic, cokes Worry, nervous, tic disorder suck finger, dig nostril etc..Also there is fingernail biting behavior in symptom bigot's night.
Fingernail biting is not the patent of child, it is many adult also can fingernail biting experience.For on psychology, gnaw in fact Fingernail biting reflects a kind of mental emotion sometimes.Often have with moods such as nervous, depressed, dejected, inferiority complex, hostile senses It closes.
Inadvertently fingernail biting will know that if conscious be noted that for we, in general we be all Under the emotional state of nervous anxiety, that can't help removes fingernail biting.French researcher has carried out a will of the people test to examine It looks into who love fingernail biting and what situation fingernail biting is under.Studies have shown that Frenchman like fingernail biting mostly with their work Make related.26% or more person likes fingernail biting when consideration works relevant thing to them.Curiously, shopping is to sting Second reason of nail: the torment of the possible masterpiece choice of fingernail biting.Consider economic situation and the concern to parent and child Row is third.
That is, our fingernail bitings, are because we have pressure, by fingernail biting come loose pressure, while we examine Consider it is some when being difficult to the problem of certainly selecting, also can fingernail biting.
Psychologist thinks, fingernail biting come relieve stress be due in as a child this behavior by strong prompting, source In the prompting that parent is strong, instead " fingernail biting " this behavior may be retained, or even the more drill the more severe, then slowly This behavior is just at a release of this one fixed mood of child and the reproduction of a relationship.Punishment can also be strong Change, for a child because something is scold and beaten, this may be a kind of reinforcing, and this reinforcing will allow him this behavior to become this Add strict.This behavior may be extended to adult.
The habit of fingernail biting is very serious for the harm of health.Children's nail is to be very easy to shelter evil people and countenance evil practices in fact , because scratching everywhere, fouling material can remain among nail slot, if fingernail biting at this time, undoubtedly be the same as directly eating Dirt, at this time serious can cause the disease of digestive tracts such as abdominal pain diarrhea.In addition, in the contact process of tooth and nail In, it is easy to it is damaged to nail groove, also there are many bacteriums in fact in oral cavity, in addition the pathogen among nail slot, will lead to nail groove Infection rate rises significantly.
Currently, it is also varied for overcoming the method for the nail that bites, and such as: all factors of children's anxiety are caused from elimination It sets out to prevent and treat the defect for the nail that bites;Parent's patient persuasion and education based on encouraging to infant, transfer infant and overcome The enthusiasm of bad habit allows children to participate in recreation more, shifts its attention, when there is fingernail biting in child, Jia Changyao The attention for dispersing child, tells a story;Good hygiene habit is formed, is often trimmed the nails;Referred to bitter taste or pungent agent smearing First-class compulsory method;Hospital can be arrived by, which frequently occurring, is corrected, and behavior rescues therapy and such as strengthens Ji, repercussion, detest method. Behaviour therapy scheme is generally designed according to infant concrete condition by doctor, assists to implement by parent, while giving the supportive heart Physical therapy method.The effect of behavior therapy depends on the close fit of three aspect of doctor, parent and infant, and to persevere.
By parent come to the defect for helping child to overcome the nail that bites, the time cycle is longer, needs parent greatly resistance to The heart, the time, which has grown child, can also generate aversion, and effect can run counter to desire sometimes, or even have the trend of exacerbation.Go medical treatment into Row correction, the course for the treatment of is longer, needs largely to pay plenty of time cost and economic cost, and common people can not adhere to getting off.Using hardship The method that taste agent and pungent agent are smeared is easy to operate, but Related product currently on the market is not strong to the adhesion of nail, together The Shi Zhijia restorative period is longer.
Summary of the invention
The present invention is directed to the above-mentioned problems in the prior art, proposes a kind of liniment for protecting nail, contains Ingredient with bitter taste, so that experiencing strong bitter taste when people bites oneself nail and stopping the movement that bites;It also contains Adsorbent can be adsorbed on nail well after smearing, even if effect can also last for hours after washing one's hands; In addition, it contains the substance for promoting nail metabolism growth, it can be the good of nail under the premise of having the effect of anti-fingernail biting It is quite long to create environment, promote nail to get well as early as possible.The specific technical solution of the present invention is as follows:
A kind of liniment for protecting nail comprising bitter principle 0.0014%-0.003% by mass, adsorbent are pressed Quality meter 0.08%-1% promotes the substance 0.1%-1% by mass of nail metabolism growth, remaining is solvent, wherein described Bitter principle is Denatonium Benzoate, and the adsorbent is acrylic acid (ester) class/Diacetone Acrylamide AMP salt, and the promotion refers to The substance of first metabolism growth is Keratin amino acids class, and the solvent is made of water and ethyl alcohol, and wherein the content of ethyl alcohol accounts for smearing The ratio of agent is 0.6%-1% by mass.
Preferably, wherein the bitter principle is 0.0014%-0.0024% by mass, adsorbent is by mass 0.08%-0.8%, promote the substance of nail metabolism growth is 0.1%-0.8% by mass, and ethyl alcohol is 0.6%- by mass 0.8%.
Preferably, wherein the bitter principle by mass 0.0021%, adsorbent by mass 0.48% promote nail The substance 0.6% of metabolism growth, ethyl alcohol by mass 0.72%.
Preferably, wherein the bitter principle by mass 0.0017%, adsorbent by mass 0.38% promote nail The substance of metabolism growth by mass 0.48%, ethyl alcohol by mass 0.58%.
The invention further relates to a kind of methods for manufacturing above-mentioned liniment, specifically includes the following steps:
A) under dustfree environment, by Keratin amino acids class, acrylic acid (ester) class/Diacetone Acrylamide AMP salt, benzene first Denatonium, ethyl alcohol and pure water are respectively put into spare in clean measuring device;
B) in required ratio measure material requested be put into be sufficiently stirred in container after stand 4-5 hours;
C) solution after standing is poured into filling apparatus carry out it is filling, according to the packaging of product specification injection not co-content In bottle, then seal.
Wherein at 5-29 degrees Celsius, relative air humidity is controlled in 40-75% for environment temperature control in the fabrication process.
Specific embodiment
Each embodiment of the invention is described below.
Denatonium Benzoate be it is a kind of by quaternary ammonium salt cationic and inert anion such as benzoate anion ion or saccharin yin from Son combines the quaternary ammonium salt formed.It is highly soluble in water, ethyl alcohol, ethylene glycol etc., and aqueous solution is in neutrality, and is known most bitter in the world Substance, just make one to be difficult to endure when concentration in the solution is up to 0.003%, be used as bitters in daily necessities and industrial goods (or aversive agent) can prevent because caused by being eaten by mistake people, animal the generation of poisoning and prevent children from biting article, because This product is used in the industrial goods such as daily necessities and plastic, rubber toy product by this many national regulation.
Referred to by adding Denatonium Benzoate the to bite people of nail biting in the liniment of protection nail of the invention Strong bitter taste is felt after first and abandons further biting, and is highly soluble in after wherein alcohol solvent is merged with Denatonium Benzoate Water, so that strong bitter taste occurs after encountering saliva for liniment, i.e. Denatonium Benzoate makes the liniment together with ethyl alcohol Comprehensive function occurs for effect.
According to the difference of children and the adult tolerance degree to bitter taste, the present invention comes by adjusting the content of Denatonium Benzoate Meet the needs of different crowd, specifically include following several embodiments:
Embodiment one: it is suitable for adult liniment ingredient
The liniment, including bitter principle 0.0014%-0.003% by mass, preferably 0.0021%, adsorbent presses matter Meter 0.08%-1%, preferably 0.48%, promote the substance 0.1%-1% by mass of nail metabolism growth, and preferably 0.6%, Remaining is solvent, wherein the bitter principle is Denatonium Benzoate, the adsorbent is acrylic acid (ester) class/diacetone acrylamide acyl Amine AMP salt, the substance for promoting nail metabolism growth is Keratin amino acids class, and the solvent is made of water and ethyl alcohol, The ratio that the content of middle ethyl alcohol accounts for liniment is 0.6%-1% by mass, preferably 0.72%.
Embodiment two: it is suitable for the liniment ingredient of children
The content for suitably reducing corresponding ingredient on the basis of example 1, is supplemented with water, is made with meeting children Needs.For example, the bitter principle is 0.0014%-0.0024% by mass, and preferably 0.0017%, adsorbent presses matter Amount is calculated as 0.08%-0.8%, preferably 0.38%, and promote the substance of nail metabolism growth is 0.1%-0.8% by mass, excellent 0.48% is selected, ethyl alcohol is 0.6%-0.8% by mass, preferably 0.58%.
The generation of the case where in order to avoid resulting in the need for frequent spread product due to product effect disappears immediately after washing one's hands, this It is added to adsorbent in the liniment of invention, product can be made to be adsorbed on nail well by adding adsorbent, even if washing Its effect still is able to last for hours after hand, for example, if it is small that product effect can continue 8-12 in the case where not washing one's hands When, if it is primary to wash one's hands, no longer smeared, effect can continue 5-6 hours, wash one's hands twice, no longer smear therebetween, effect can With 2-3 hours lasting.It repeatedly washes one's hands in one hour, such as using detergent etc., bitter taste can be eliminated, protective effect disappears.
Liniment application method of the invention is simple, and one liang of drop need to be only dripped on finger nail and is directly smeared, or is fallen Enter in sub-bottling, using hairbrush brush on nail, then can play the role of within natural air drying 2-3 minutes protecting nail.
This liniment is due to the substance containing promotion nail metabolism growth, so can promote to refer to while protecting nail First metabolism growth creates good growing environment for nail, so that nail is got well as early as possible.Contain absorption in this liniment Agent enables the substance for playing main function to be firmly adsorbed on nail, can persistently play a role washing one's hands, without frequency Numerous smearing, and acrylic acid (ester) class/Diacetone Acrylamide AMP salt Small side effects are suitble to various people to use.In addition, second Alcohol is solvent very handy in cosmetics, can play fusion, plays better stability, by the fusion of ethyl alcohol it Make liquid have certain density afterwards, can better adhere on nail surface.
Embodiment three: a method of above-mentioned liniment is manufactured, specifically includes the following steps:
A) under dustfree environment, by Keratin amino acids class, acrylic acid (ester) class/Diacetone Acrylamide AMP salt, benzene first Denatonium, ethyl alcohol and pure water are respectively put into spare in clean measuring device;
B) in required ratio measure material requested be put into be sufficiently stirred in container after stand 4-5 hours;
C) solution after standing is poured into filling apparatus carry out it is filling, according to the packaging of product specification injection not co-content In bottle, then seal.
Wherein at 5-29 degrees Celsius, relative air humidity is controlled in 40-75% for environment temperature control in the fabrication process.
The manufacture of liniment of the invention needs to control environment temperature, and temperature is too low to be easy to freeze material, and temperature is too high Material is unstable volatile, especially water and ethyl alcohol.
Although the embodiment of the present invention is described in detail in the above content, but it is understood that above-described embodiment is only Be exemplary, be not considered as limiting the invention, those skilled in the art can not depart from marrow of the invention and Modification, modification and replacement are carried out to above-described embodiment under the premise of principle, and these modifications, modification and replacement are of the invention Within protection scope.

Claims (6)

1. a kind of liniment for protecting nail comprising bitter principle 0.0014%-0.003% by mass, adsorbent press matter Meter 0.08%-1% promotes the substance 0.1%-1% by mass of nail metabolism growth, remaining is solvent, wherein the hardship Taste ingredient is Denatonium Benzoate, and the adsorbent is acrylic acid (ester) class/Diacetone Acrylamide AMP salt, the promotion nail The substance of metabolism growth is Keratin amino acids class, and the solvent is made of water and ethyl alcohol, and wherein the content of ethyl alcohol accounts for liniment Ratio be by mass 0.6%-1%.
2. liniment according to claim 1, wherein the bitter principle is 0.0014%-0.0024% by mass, Adsorbent is 0.08%-0.8% by mass, and promote the substance of nail metabolism growth is 0.1%-0.8%, ethyl alcohol by mass It is by mass 0.6%-0.8%.
3. liniment according to claim 1, wherein the bitter principle by mass 0.0021%, adsorbent presses quality Meter 0.48% promotes the substance 0.6% of nail metabolism growth, ethyl alcohol by mass 0.72%.
4. liniment according to claim 1, wherein the bitter principle by mass 0.0017%, adsorbent presses quality Meter 0.38% promotes the substance by mass 0.48% of nail metabolism growth, ethyl alcohol by mass 0.58%.
5. a kind of manufacture the method for stating liniment described in any one of -4 according to claim 1, specifically includes the following steps:
A) under dustfree environment, by Keratin amino acids class, acrylic acid (ester) class/Diacetone Acrylamide AMP salt, benzene first ground that Ammonium, ethyl alcohol and pure water are respectively put into spare in clean measuring device;
B) in required ratio measure material requested be put into be sufficiently stirred in container after stand 4-5 hours;
C) solution after standing is poured into filling apparatus carry out it is filling, according to the Packaging Bottle of product specification injection not co-content In, then seal.
6. according to the method described in claim 5, wherein environment temperature control is at 5-29 degrees Celsius in the fabrication process, air phase To humid control in 40-75%.
CN201910468355.6A 2019-05-24 2019-05-24 A kind of liniment and its manufacturing method for protecting nail Pending CN110051556A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
CN201910468355.6A CN110051556A (en) 2019-05-24 2019-05-24 A kind of liniment and its manufacturing method for protecting nail

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CN110051556A true CN110051556A (en) 2019-07-26

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114306474A (en) * 2021-12-17 2022-04-12 广西萌大夫生物技术有限公司 Finger stall for correcting pica and promoting nail growth and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030185775A1 (en) * 2002-04-01 2003-10-02 Digiulio Aristodemo C. Cosmetic composition
CN103110566A (en) * 2013-01-31 2013-05-22 巫国谊 External pigmentum for correcting bad habit of finger sucking of infants
CN105998544A (en) * 2016-05-31 2016-10-12 周国文 Bitter aversive agent and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030185775A1 (en) * 2002-04-01 2003-10-02 Digiulio Aristodemo C. Cosmetic composition
CN103110566A (en) * 2013-01-31 2013-05-22 巫国谊 External pigmentum for correcting bad habit of finger sucking of infants
CN105998544A (en) * 2016-05-31 2016-10-12 周国文 Bitter aversive agent and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114306474A (en) * 2021-12-17 2022-04-12 广西萌大夫生物技术有限公司 Finger stall for correcting pica and promoting nail growth and preparation method thereof

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