CN110051348A - A kind of flexible electronic detection patch and man-machine interactive system - Google Patents
A kind of flexible electronic detection patch and man-machine interactive system Download PDFInfo
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- CN110051348A CN110051348A CN201910252409.5A CN201910252409A CN110051348A CN 110051348 A CN110051348 A CN 110051348A CN 201910252409 A CN201910252409 A CN 201910252409A CN 110051348 A CN110051348 A CN 110051348A
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- patch
- conductive film
- annular electrode
- flexible electronic
- flexible
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6814—Head
Abstract
The present invention discloses a kind of flexible electronic detection patch and man-machine interactive system, wherein flexible electronic detection patch includes: between the first patch conductive film, the second patch conductive film and third patch conductive film of distribution setting by flexible connection line connection；First patch conductive film, the second patch conductive film, third patch conductive film and flexible connection line respectively include regularly arranged multiple topological structures, pass through waveform microstructure brazing between each node of topological structure；First patch conductive film, the second patch conductive film, third patch conductive film and flexible connection line and user skin attachement, detect the EEG signals of user.Flexible electronic detection patch in the present invention uses between each node for dividing shape topological structure through waveform microstructure brazing, its flexible resilient modulus ultra-thin and with higher, it can be contacted with dry human skin, the EEG signals of self-closing disease patient can be measured for a long time, this has very great help to the rehabilitation tool of self-closing disease patient.
Description
Technical field
The present invention relates to field of biomedicine technology, and in particular to a kind of flexible electronic detection patch and human-computer interaction system
System.
Background technique
It is traditionally used for detecting the biological integrated-optic device of cerebral neural EEG signals at present, generally passes through noninvasive note
The direct skin contact of metal or dielectric gel electrode and user is recorded, and then collects the brain electricity of user by electrode stimulating
Signal, the metal electrode or dielectric gel electrode directly contact the skin of user, and the skin for easily causing user occurs
Allergic reaction, meanwhile, it can also allow user to generate discomfort.In addition, if for a long time using the biology integrated-optic device
The EEG signals for detecting user do not have spring function due to metal electrode or dielectric gel, if carried out for a long time
Electrode stimulating obtains the EEG signals of user, is easy the elastic property of degeneration user skin interface, leads to EEG signals
Detection accuracy reduces, so, traditional biological Integrated electrode device can not detect the EEG signals of user for a long time.
Summary of the invention
In view of this, the embodiment of the invention provides a kind of flexible electronics to detect patch, it is integrated to solve existing biology
Wearing comfort degree existing for electronic device is lower, and the problem of can not measure the EEG signals of user for a long time.
According in a first aspect, the embodiment of the invention provides a kind of flexible electronics to detect patch, comprising: be distributed the of setting
One patch conductive film, the second patch conductive film and third patch conductive film, the first patch conductive film, second patch are led
It is connected between electrolemma and the third patch conductive film by flexible connection line；The first patch conductive film, second patch
Piece conductive film, the third patch conductive film and the flexible connection line respectively include regularly arranged multiple topological structures,
Pass through waveform microstructure brazing between each node of the topological structure；The first patch conductive film, second patch
The skin attachement of piece conductive film, the third patch conductive film and the flexible connection line and user, and then make described in detection
The EEG signals of user.
With reference to first aspect, in first aspect first embodiment, the topological structure is to divide shape topological structure, is constituted
Each side of described point of shape topological structure is the waveform micro-structure.
With reference to first aspect, in first aspect second embodiment, the topological structure is triangle topology structure, structure
Each side at the triangle topology structure is the waveform micro-structure.
With reference to first aspect, in first aspect third embodiment, the first patch conductive film, second patch
Conductive film and the third patch conductive film are used to contact with the fitting of the ear skin region of the user.
According to second aspect, the embodiment of the present invention provides a kind of flexible electronic detection patch, comprising: at least one set of ring attaching
Piece conductive film, flexible connection line and conductive contact layer；Annular patch conductive film described in every group includes first annular electrode, the second ring
Shape electrode and third annular electrode, the circle of the first annular electrode, second annular electrode and the third annular electrode
Heart overlapping, annular patch conductive film described in every group is connected on the conductive contact layer by the flexible connection line, and described the
One annular electrode, second annular electrode, the third annular electrode and the flexible connection line respectively include regularly arranged
Multiple topological structures, pass through waveform microstructure brazing between each node of the topological structure；Ring attaching described in every group
Piece conductive film passes through the skin contact of flexible elastomer and user, and then detects the EEG signals of the user.
In conjunction with second aspect, in second aspect first embodiment, the topological structure is to divide shape topological structure, is constituted
Each side of described point of shape topological structure is the waveform micro-structure.
In conjunction with second aspect, in second aspect second embodiment, the topological structure is triangle topology structure, structure
Each side at the triangle topology structure is the waveform micro-structure.
It is described in annular patch conductive film described in every group in second aspect third embodiment in conjunction with second aspect
First annular electrode, the second annular electrode and the third annular electrode are connected to the conduction by the flexible connection line and connect
In contact layer.
In conjunction with second aspect third embodiment, in the 4th embodiment of second aspect, the first annular electrode, institute
It states the second annular electrode and the third annular electrode is used to contact with the fitting of the ear skin region of the user.
In conjunction with the 4th embodiment of second aspect, in the 5th embodiment of second aspect, the first annular electrode, institute
It is identical with the size of the third annular electrode to state the second annular electrode.
According to the third aspect, the embodiment of the present invention provides a kind of man-machine interactive system, comprising: brain electric test equipment and above-mentioned
Flexible electronic described in any one embodiment detects patch, and the brain electric test equipment and the flexible electronic detect patch
Connection.
Technical solution of the embodiment of the present invention, has the advantages that
The present invention provides a kind of flexible electronic detection patch and man-machine interactive system, wherein flexible electronic detects patch packet
It includes: being distributed between the first patch conductive film, the second patch conductive film and third patch conductive film of setting and pass through flexible connection line
Connection；First patch conductive film, the second patch conductive film, third patch conductive film and flexible connection line respectively include regular row
Multiple topological structures of column pass through waveform microstructure brazing between each node of topological structure；First patch conductive film,
The skin attachement of two patch conductive films, third patch conductive film and flexible connection line and user detects the brain telecommunications of user
Number.Connected between each node that flexible electronic detection patch in the present invention passes through point shape topological structure by waveform micro-structure
It connects, flexible resilient modulus ultra-thin and with higher can be contacted with dry human skin, can measure self-closing disease trouble for a long time
The EEG signals of person, this has very great help to the rehabilitation tool of self-closing disease patient.
Detailed description of the invention
It, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution in the prior art
Embodiment or attached drawing needed to be used in the description of the prior art be briefly described, it should be apparent that, it is described below
Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor
It puts, is also possible to obtain other drawings based on these drawings.
Fig. 1 is the structural schematic diagram of biopolymer in the embodiment of the present invention；
Fig. 2 is the first structure diagram that flexible electronic detects patch in the embodiment of the present invention；
Fig. 3 is the schematic diagram of multiple points of shape topological structures in the embodiment of the present invention；
Fig. 4 is the enlarged diagram of medium wave of embodiment of the present invention shape wave micro-structure；
Fig. 5 is the schematic diagram for each dividing shape topological structure in the embodiment of the present invention；
Fig. 6 A is the schematic diagram of intermediate cam of embodiment of the present invention shape topological structure；
Fig. 6 B is the schematic diagram of honeycombed topological structure in the embodiment of the present invention；
Fig. 6 C is Kagome topological structure schematic diagram in the embodiment of the present invention；
Fig. 7 A is the curve graph that flexible electronic detects patch when installing in the embodiment of the present invention；
Fig. 7 B is the curve graph that flexible electronic detects patch after installing 24 hours in the embodiment of the present invention；
Fig. 8 A is that flexible electronic detects patch in the EEG signals of first day measurement user in the embodiment of the present invention；
Fig. 8 B is that flexible electronic detects patch in the EEG signals of the 7th day measurement user in the embodiment of the present invention；
Fig. 8 C is that flexible electronic detects the EEG signals that patch measures user in fortnight in the embodiment of the present invention；
Fig. 9 is the second structural schematic diagram that flexible electronic detects patch in the embodiment of the present invention；
Figure 10 is the structural schematic diagram of every group of annular patch conductive film in the embodiment of the present invention.
Appended drawing reference:
21- the first patch conductive film；22- the second patch conductive film；23- third patch conductive film；
24- flexible connection line；25- annular patch conductive film；26- conductive contact layer；
The first annular electrode of 251-；The second annular electrode of 252-；253- third annular electrode.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention
In attached drawing, technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described embodiment is
A part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, those skilled in the art are not having
Every other embodiment obtained under the premise of creative work is made, shall fall within the protection scope of the present invention.
Embodiment 1
The embodiment of the present invention provides a kind of flexible electronic detection patch, and flexible electronic patch herein can be applied in biology
Medicine technology field, and then the EEG signals of self-closing disease patient are detected, this is to the early diagnosis of self-closing disease patient, treatment and right
The control and improvement of the nervous system disease are of great significance.
Find that the composite material of hard and soft structures composition provides inspiration for building novel synthetic material in biology.
Fig. 1 is the structural schematic diagram of biopolymer.As shown in Figure 1, the solid line for connecting each solid dot indicates the collagen in biosystem
Albumen and elastin laminin, these collagens and elastin laminin are filled in biological tissue, and biological tissue is made to have elasticity.Pass through
The structure of imitated biological tissue can construct flexible bionic object structure, to realize the mechanical performance to skin or biological tissue
Simulation, so that flexible bionic object structure and the Nonlinear extension performance of skin or biological tissue is matched.
Flexible electronic detection patch combination flexible bionic object structure in the embodiment of the present invention can be with skin or biological group
The Nonlinear extension performance matching knitted, as shown in Fig. 2, specifically including: being distributed the first patch conductive film 21, second patch of setting
Piece conductive film 22 and third patch conductive film 23.In Fig. 2, the first patch conductive film 21 is measuring electrode (REC), the second patch
Conductive film 22 is grounding electrode (GND), and third patch conductive film 23 is reference electrode (REF), the first patch conductive film 21, second
The elastomer thin film that modulus is 20kPa is respectively adopted in patch conductive film 22 and third patch conductive film 23, the elastomer thin film
With a thickness of 3 μm, the elastomer thin film of 3 μ m thicks can guarantee its flexibility fitting on a user's skin, to realize for a long time
Measure the EEG signals of user.
Specifically, it can be seen that in Fig. 2, the first patch conductive film 21, the second patch conductive film 22 and third patch are conductive
It is connected between film 23 by flexible connection line 24, the modulus of the flexible connection line 24 is also 20kPa, therefore, should with a thickness of 3 μm
Flexible connection line 24 also has certain elasticity, can guarantee its flexibility fitting on a user's skin.
In a specific embodiment, as shown in figure 3, the first patch conductive film 21, the second patch conductive film 22, third patch
Piece conductive film 23 and flexible connection line 24 respectively include regularly arranged multiple topological structures, each section of each topological structure
Pass through waveform microstructure brazing between point.The waveform micro-structure has certain tensility.As shown in figure 4, being wave
The enlarged drawing of shape micro-structure, arc angle θ, wavy radius are R, width W.First patch conductive film 21, second
The skin attachement of patch conductive film 22, third patch conductive film 23 and flexible connection line 24 and user, and then detect user
EEG signals.Flexible patch conductive film and flexible connection line 24 and the skin of user with certain elastic property are close
After fitting, the EEG signals (EEG signal) of user can be detected for a long time.User herein is mainly self-closing disease patient.
In a specific embodiment, the flexible electronic in the embodiment of the present invention detects patch, in Fig. 3, topological structure
To divide shape topological structure, constitutes and each side of shape topological structure is divided to be waveform micro-structure.Herein divide shape topological structure with
Peano curve is that the fractal curve configuration of representative crosses over entire patch conductive film to enhance mechanical property, and customization has and uses
Person's skin requires the oriented anisotropic to match.In particular, interconnection uses all vertical Peano curves, to maximize along it
The draftability of the longitudinal axis is on the contrary, electrode designs to balance directive draftability using half.As shown in figure 5, being a point shape topology
The enlarged drawing of structure, the first patch conductive film 21, the second patch conductive film 22 and third patch conductive film 23, which use, divides shape topological
Structure, effective modulus are about 130kPa lower than the effective modulus of skin, to ensure bringing into conformal contact and good bonding viscosity.
In an other interchangeable specific embodiments, the flexible electronic in the embodiment of the present invention detects patch, such as schemes
Shown in 6A, topological structure can be triangle topology structure, and each side for constituting triangle topology structure is waveform micro-structure,
In fig. 6, the structure in dotted line frame is a triangle topology structure.
In an other interchangeable specific embodiments, the flexible electronic in the embodiment of the present invention detects patch, such as schemes
Shown in 6B-6C, topological structure can also be honeycombed topological structure or Kagome topological structure, constitute honeycombed topological structure or
Each side of Kagome topological structure is waveform micro-structure.Shown in Fig. 6 B to Fig. 6 C, respectively honeycombed topological structure and
The structural schematic diagram of Kagome topological structure.In fig. 6b, the structure in dotted line frame is a honeycombed topological structure, in Fig. 6 C
In, the structure in dotted line frame is a Kagome topological structure.Certainly, the topological structure in the present embodiment can also be other more
Side shape topological structure, is not limited.
In a specific embodiment, the flexible electronic detection patch in the embodiment of the present invention, the first patch conductive film 21,
Second patch conductive film 22 and third patch conductive film 23 are used to contact with the fitting of the ear skin region of user.Specifically,
First patch conductive film 21 is used to contact with the fitting of the mastoid process of user's ear, and the second patch conductive film 22 is used for user's
Fossa triangularis fitting contact, third patch conductive film 23 is used to show consideration for splice grafting touching with the top backpitch of user, due to this implementation
The first patch conductive film 21, the second patch conductive film 22 and third patch conductive film 23 in example is ultra-thin, easily curved characteristic,
So can be fitted in completely on the ear skin region of user, certainly, the first patch conductive film 21, the second patch are conductive
Film 22 and third patch conductive film 23 can also be fitted on the skin area at the other positions of user.
In a specific embodiment, the flexible electronic in the embodiment of the present invention detects patch, in order to enable the first patch
Conductive film 21, the second patch conductive film 22 and third patch conductive film 23 are bonded completely with the skin of user and contact, Jin Erti
The accuracy of high EEG signals measurement, can be operated by following installation method, the first patch conductive film 21, second is pasted
Piece conductive film 22, third patch conductive film 23 and the fitting of flexible connection line 24 are on a user's skin.Specific step is as follows:
Flexible electronic detection patch is placed in water-soluble polymer by the first step.Water-soluble polymer herein is also known as
Water-soluble resin or water soluble polymer are a kind of hydrophilic high molecular materials, can dissolve in water or be swollen and formed molten
Liquid or dispersion liquid.So flexible electronic detection patch is placed in water-soluble polymer, in order to enhance its hydrophily, in turn
Enhance the viscosity of flexible electronic detection patch.Water-soluble polymer in the present embodiment can be polyvinyl alcohol (PVA).
Second step, the predetermined patterns using razor in user's skin reject hair.Predetermined patterns herein predominantly make
It is pasted by the hair in user's ear skin region to rejecting convenient for the first patch conductive film 21, second in user's ear skin region
The installation of piece conductive film 22 and third patch conductive film 23.
Third step cleans predetermined patterns using sterilised object.Sterilised object herein is mainly sterile alcohol pads, uses nothing
Alcohol pads gently rub user predetermined patterns skin area with clean surface, i.e., gently rub user ear skin
Region is with clean surface.
Flexible electronic detection patch is fitted on predetermined patterns by the 4th step using tweezers.By using aseptic plastic tweezer
First patch conductive film 21, the second patch conductive film 22 and third patch conductive film 23 are manually placed in predetermined patterns by son
On.Soft bonding from Van der Waals interaction keeps flexible electronic patch on the skin.
5th step is sprayed onto the back that water-soluble polymer is dissolved on the conductive film of flexible electronic detection patch using clear water
Lining.The purpose that the back sheet of water-soluble polymer dissolves is so that ultra-thin flexible electronic detection patch and user are pre-
If the skin at position is bonded contact completely, if fitting is bad, will lead in the EEG signals of user there are high background noise,
So needing to examine the water solubility at flexible electronic patch conductive film for successfully installing flexible electronic patch conductive film
Polymer is completely dissolved critically important.
Flexible electronic detection patch can be bonded with uneven surface, such as: flexible electronic detection patch and user
The contact of ear skin region.As FInite Element (FEM) analysis is revealed, these behaviors follow flexible and Ke La
The special level of stretching property.Bending angle is 180 ° and when radius of curvature is 0.5mm as the result is shown by bending and the FEM folded, soft
Maximum principal strain in property detection of electrons patch is only that 0.25% (elastic limit of Au: 0.3%), this can guarantee flexible electronic
Detection patch is deformed in being used for multiple times without generating destruction, uses result to guarantee that height is duplicate.In uniaxial tensile load
Under further FEM analysis shows the first patch conductive film 21, the second patch conductive film 22, third patch conductive film 23 and soft
Property connecting line 24, which can stretch, is up to about 50%.These are the result shows that can adapt to be greater than mean skin deformation (10-20%)
Until and including maximum strain relevant to motion of knee joint (about 50%).
This flexible electronic detection patch for being mounted on user's ear skin region is for recording and explaining brain-machine interaction
(BCI) EEG signal can easily capture the standard EEG signal of such as alpha rhythm.First patch conductive film 21 is measurement electricity
(REC) is contacted with the mastoid process of user for pole, and the second patch conductive film 22 is the earlobe contacts of grounding electrode (GND) and user,
Third patch conductive film 23 is that reference electrode (REF) is contacted with the top backpitch of user, these three patch conductive films are formed
Bipolar montage.First patch conductive film 21 is measuring electrode (REC) and third patch conductive film 23 is that reference electrode (REF) is surveyed
It measures differential amplitude (REC and REF), the second patch conductive film 22 is that grounding electrode (GND) prevents the non-specificity from body from posting
Raw signal.
Fig. 7 A and Fig. 7 B are shown in the P300 EEG signals data of collection skin (mastoid process and forehead) upper 24 hour.Signal-to-noise ratio
(SNR) correspond to the ratio of signal power (coming from target) with noise power (from non-targeted).The SNR value of both of these case is several
It is identical, and they are suitable with the signal that the conventional electrodes with Signa Gel using new opplication obtain.It is used for a long time
Another example is related to recording the electroencephalogram alpha rhythm from auricle and mastoid process within 2 weeks.Alpha's rhythm usually has 8
Frequency between 12 hertz, centered on about 10 hertz.During opening and closing eyes, during awake loosen
Record the raw EEG signal for appearing in the corresponding display of EEG spectrogram of 5 to 15 hertz frequencies for the 1st day to the 14th day.Fig. 8 A, figure
Be respectively in 8B and Fig. 8 C occur on day 1, the raw EEG signal of the 7th day and the 14th day, appear in about 30 seconds sharp spies
Sign corresponds to the signal that flashing generates.Conceptual data shows day no significant difference from the 1st day to the 14th.Water-soluble polymer
External coating be it is ventilative, so as to avoid adverse side effect relevant to perspiration during the activity involved in long-term evaluation.Slightly
Micro- increased levels of background noise, especially at the 14th day, it may be possible to tired due to the dead cell that falls off naturally on skin surface
Caused by product.
Flexible electronic in the embodiment of the present invention detects patch, passes through the first patch conductive film 21, the second patch conductive film
22, third patch conductive film 23 and flexible electronic patch use the design for dividing shape topological structure, and divide each of shape topological structure
By waveform microstructure brazing between node, tensility is made it have, structure is ultra-thin and flexible resilient with higher
Modulus can be contacted with dry human skin, therefore, can measure the EEG signals of self-closing disease patient for a long time, this is to self-closing
The rehabilitation tool of disease patient has very great help.
Embodiment 2
The embodiment of the present invention provides a kind of flexible electronic detection patch, as shown in figure 9, the flexible electronic detects patch packet
It includes: one group of annular patch conductive film 25, flexible connection line 24 and conductive contact layer 26.As other interchangeable embodiments,
Flexible electronic detection patch in the present embodiment can also include multiple groups annular patch conductive film 25, flexible connection line 24 and conduction
Contact layer 26,25 forming array structure of multiple groups annular patch conductive film, multiple groups annular patch conductive film 25 is for detecting user
EEG signals caused by different parts skin region, in Fig. 9, respectively by eight groups of 25 forming array knots of annular patch conductive film
Structure, every group of annular patch conductive film 25 can be used alone.Such as: wherein one group of annular patch conductive film 25 can be used and measure
The EEG signals that user's ear skin region generates.Specifically, for multiple groups annular patch conductive film 25 and flexible connection line
24, the flexible electronic that conductive contact layer 26 is constituted detects patch, has multiple interface channels in flexible connection line 24, in conduction
Also there are multiple conductive channels, every group of annular patch conductive film 25 is connected by corresponding interface channel respectively in contact layer 26
It connects on corresponding conductive channel, such as: there are eight groups of annular patch conductive films 25, first group of annular patch is led in the present embodiment
Electrolemma 25 is connect by the first interface channel of flexible connection line 24 with the first conductive channel of conductive contact layer 26, second group of ring
Shape patch conductive film 25 is connect by the second interface channel of flexible connection line 24 with the second conductive channel of conductive contact layer 26,
Third group annular patch conductive film 25 is led by the third interface channel of flexible connection line 24 and the third group of conductive contact layer 26
Electric channel connection, the 4th interface channel and conductive contact layer 26 that the 4th group of annular patch conductive film 25 passes through flexible connection line 24
The connection of the 4th conductive channel, the 5th group of annular patch conductive film 25 pass through the 5th interface channel of flexible connection line 24 and conductive
5th conductive channel of contact layer 26 connects, and the 6th group of annular patch conductive film 25 is logical by the 6th connection of flexible connection line 24
Road is connect with the 6th conductive channel of conductive contact layer 26, the 7th group of annular patch conductive film 25 pass through flexible connection line 24 the
Seven interface channels are connect with the 7th conductive channel of conductive contact layer 26, and the 8th group of annular patch conductive film 25 passes through flexible connection
8th interface channel of line 24 is connect with the 8th conductive channel of conductive contact layer 26,
In Fig. 9, every group of annular patch conductive film 25 includes first annular electrode 251, the second annular electrode 252 and third
Annular electrode 253.The size of first annular electrode 251 herein, the second annular electrode 252 and third annular electrode 253 can be with
It is identical, it is the enlarged drawing of every group of annular patch conductive film 25, each annular electrode is respectively by two annulus and one as shown in Figure 10
A center of circle is constituted.In Figure 10, first annular electrode 251, the second ring heart electrode and third annular electrode 253 are stacked, and
Its center of circle can be overlapped, but during use, first annular electrode 251, the second annular electrode 252 and third annular
Electrode 253 is contacted with the fitting of the different parts of user respectively.First annular electrode 251, the second annular electrode 252 and third ring
Shape electrode 253 is used to contact with the fitting of the ear skin region of user.Such as；First annular electrode 251 is used for and user
The top backpitch of ear is bonded contact, and the second annular electrode 252 is for the ear-lobe leaflet-contact with user, third annular electro
Pole 253 with the mastoid process of the ear of user for contacting.
In Fig. 9, the first annular electrode 251 of every group of ring shaped conductive film, the second annular electrode 252 and third annular electrode
253 center of circle can be overlapped, and every group of annular patch conductive film 25 is connected on conductive contact layer 26 by flexible connection line 24,
First annular electrode 251, the second annular electrode 252, third annular electrode 253 and flexible connection line 24 respectively include
Regularly arranged multiple topological structures pass through waveform microstructure brazing between each node of topological structure.Each annular electro
Pole is made of regularly arranged multiple topological structures, and each topological structure is to divide shape topological structure, and composition divides shape topological structure
Each side be waveform micro-structure, in Fig. 5 be waveform micro-structure enlarged drawing.Herein divide shape topological structure with
Peano curve be representative fractal curve configuration across entire patch conductive film to generate enhancing mechanical property, customization have with
User's skin requires the oriented anisotropic to match.In particular, interconnection uses all vertical Peano curves, to maximize
Draftability along its longitudinal axis is on the contrary, electrode designs to balance directive draftability using half.As shown in figure 3, being a point shape
The enlarged drawing of topological structure, first annular electrode 251, the second annular electrode 252 and third annular electrode 253, which use, divides shape topological
Structure, effective modulus are lower than the effective modulus (about 130kPa) of skin, to ensure that bringing into conformal contact and good bonding are viscous
Property.
In an other interchangeable specific embodiments, the flexible electronic in the embodiment of the present invention detects patch, such as schemes
Shown in 6A, topological structure can be triangle topology structure, and as shown in Fig. 6 B to Fig. 6 C, dividing can also be honeycombed topological structure
Or Kagome topological structure, each side for constituting triangle topology structure is waveform micro-structure, in fig. 6, in dotted line frame
Structure is a triangle topology structure；Each side for constituting honeycombed topological structure or Kagome topological structure is that waveform is micro-
Structure, in fig. 6b, the structure in dotted line frame are a Kagome topological structure, and in figure 6 c, the structure in dotted line frame is one
A honeycombed topological structure.First annular electrode 251, the second annular electrode 252 and third annular electrode 253 and flexible connection line
24 are all made of the topological structure of waveform micro-structure, its elastic stress can be enhanced, and keep its tensile property more preferable, and then can mention
The detection accuracy of high EEG signals.
Every group of annular patch conductive film 25 passes through the skin contact of flexible elastomer and user, and then detects user's
EEG signals.Flexible elastomer herein be silicone polymer, the flexible elastomer with a thickness of 3 μm.
In a specific embodiment, the flexible electronic in the embodiment of the present invention detects patch, as shown in figure 9, every group of ring
First annular electrode 251, the second annular electrode 252 and third annular electrode 253 in shape patch conductive film 25 are connected by flexible
Wiring 24 is connected on conductive contact layer 26.Conductive contact layer 26 herein is engagement pad, for every group of annular patch is conductive
The signal collected of film 25 is collected, and is then connect with external measuring circuitry.First annular electrode 251 herein can be used as
Measuring electrode uses, and the second annular electrode 252 can be used as grounding electrode use, and third annular electrode 253 can be used as reference
Electrode uses.
In order to record electroencephalogram alpha rhythm, by first annular electrode 251, the second annular electrode 252 and third annular electrode
253 fittings on a user's skin, can obtain the EEG signals of user's skin.
Flexible electronic in the embodiment of the present invention detects patch, passes through the first annular electricity of every group of annular patch conductive film 25
Pole 251, the second annular electrode 252, third annular electrode 253 and flexible connection line 24 use the design for dividing shape topological structure,
And divide between each node of shape topological structure through waveform microstructure brazing, tensility is made it have, structure is ultra-thin
And therefore flexible resilient modulus with higher, the human skin contact that can be dried, can measure self-closing disease patient's for a long time
EEG signals, this has very great help to the rehabilitation tool of self-closing disease patient.
Embodiment 3
The embodiment of the present invention provides a kind of man-machine interactive system, comprising: brain electric test equipment and embodiment 1 or embodiment 2
In flexible electronic detect patch, brain electric test equipment and flexible electronic detect patch and connect.Brain electric test equipment master herein
It to be external circuit, for the EEG signals of auxiliary flexible detection of electrons patch measurement user, such as: brain electric test equipment packet
Include preamplifier, low-pass filter, analog-digital converter, classifier, the oscillograph etc. of ultra-high input impedance.Flexible electronic
Detection patch detects that the EEG signals of user need to amplify by preamplifier and low-pass filter is filtered
Wave.
It can illustrate the record of EEG EEG signals data and with the power of test being continuously used for a long time by BCI experiment.
Visual evoked potential is as the basis based on Steady State Visual Evoked Potential (SSVEP) and the BCI of P300 event related potential.Test
The attention process of person influences signal amplitude, so that the information about the target of one group of tester to be rendered as to the basis of BCI.
The feasibility of the BCI based on SSVEP is demonstrated using with normal or normal three male volunteers of correcting defects of vision.The experiment
It is related to the not test of same date and experimental courses.Data are generated using the initial assessment of one group of 40 traditional electrode to instruct electrode
Best orientation, each participant participated in a series of SSVEP stimulation, electroencephalographic record occurs during 60 tests,
Test has single stimulation flashing 20 seconds of 6,6.67,7.5,8.57 or 10Hz every time, and test bay 5 seconds invalid.Determination is most preferably put
It sets and canonical correlation analysis (CCA) is based on to the algorithm that online experiment is classified.It will be from flexible electronic detection patch
SSVEP is compared with the SSVEP from traditional electrode, as a result shows similar mode and amplitude.The present embodiment research exists
Four positions (auricle, mastoid process and forehead) of user acquire base-line data using conventional electrodes, and are compared with flexible electrode
Compared with to measure P300 EEG signals data.Participant answers a series of words, including " brown ", " fox ", " epidermis " and
" electrode ".Our data mainly show that the ingredient of P300 is 0.3-4Hz.200 before data baseline correction is started to stimulation
It the millisecond period, is then averaged to generate ERP.The P300 (ERP) of record, the result of (Fig. 7 A and 7B) have clearly distinguished pair
The reaction of target and non-targeted stimulation.
The flexible electronic detection patch for including in the embodiment of the present invention, is a kind of soft and folding electrode sets, adopts
The surface topology of complicated auricle and mastoid process can directly and be chronically mounted on open wave point shape grid geometry
Structure provides high fidelity and capture electroencephalogram avoids any apparent thermoelectricity or mechanical load in skin for a long time in some way
On.Experiment and calculate research establish bending and stretching mechanical basic sides this make it is such highly irregular intimate
Integrate auricle and grain surface.Cellular level test and heat imaging research establish biocompatibility and the such system of wearability
System, the example period for having high-quality measurement are 2 weeks, and equipment remains that installation condition daily routines include strenuous exercise, swimming,
Sleep, and have a bath.
Obviously, the above embodiments are merely examples for clarifying the description, and does not limit the embodiments.It is right
For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of variation or
It changes.There is no necessity and possibility to exhaust all the enbodiments.And it is extended from this it is obvious variation or
It changes still within the protection scope of the invention.
Claims (11)
1. a kind of flexible electronic detects patch characterized by comprising
It is distributed the first patch conductive film, the second patch conductive film and the third patch conductive film of setting, first patch is conductive
It is connected between film, the second patch conductive film and the third patch conductive film by flexible connection line；
The first patch conductive film, the second patch conductive film, the third patch conductive film and the flexible connection
Line respectively includes regularly arranged multiple topological structures, is connected between each node of the topological structure by waveform micro-structure
It connects；
The first patch conductive film, the second patch conductive film, the third patch conductive film and the flexible connection line
With the skin attachement of user, and then the EEG signals of the user are detected.
2. flexible electronic according to claim 1 detects patch, which is characterized in that the topological structure is to divide shape topology knot
Structure, it is the waveform micro-structure that each side of shape topological structure is divided described in composition.
3. flexible electronic according to claim 1 detects patch, which is characterized in that the topological structure is triangle topology
Structure, each side for constituting the triangle topology structure is the waveform micro-structure.
4. the application method of flexible electronic detection patch according to claim 1, which is characterized in that first patch is led
Electrolemma, the second patch conductive film and the third patch conductive film with the ear skin region of the user for being bonded
Contact.
5. a kind of flexible electronic detects patch characterized by comprising at least one set of annular patch conductive film, flexible connection line
And conductive contact layer；
Annular patch conductive film described in every group includes first annular electrode, the second annular electrode and third annular electrode, and described
The center of circle of one annular electrode, second annular electrode and the third annular electrode is overlapped, and annular patch described in every group is conductive
Film is connected on the conductive contact layer by the flexible connection line, the first annular electrode, second annular electrode,
The third annular electrode and the flexible connection line respectively include regularly arranged multiple topological structures, the topological structure
Pass through waveform microstructure brazing between each node；
Annular patch conductive film described in every group passes through the skin contact of flexible elastomer and user, and then detects the user
EEG signals.
6. flexible electronic according to claim 5 detects patch, which is characterized in that the topological structure is to divide shape topology knot
Structure, it is the waveform micro-structure that each side of shape topological structure is divided described in composition.
7. flexible electronic according to claim 5 detects patch, which is characterized in that the topological structure is triangle topology
Structure, each side for constituting the triangle topology structure is the waveform micro-structure.
8. flexible electronic according to claim 5 detects patch, which is characterized in that in annular patch conductive film described in every group
The first annular electrode, the second annular electrode and the third annular electrode be connected to by the flexible connection line it is described
On conductive contact layer.
9. flexible electronic according to claim 8 detects patch, which is characterized in that the first annular electrode, described the
Second ring electrode and the third annular electrode are used to contact with the fitting of the ear skin region of the user.
10. flexible electronic according to claim 9 detects patch, which is characterized in that the first annular electrode, described the
Second ring electrode is identical with the size of the third annular electrode.
11. a kind of man-machine interactive system characterized by comprising brain electric test equipment and any one of such as claim 1-10
The flexible electronic detects patch, and the brain electric test equipment is connect with flexible electronic detection patch.
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