CN110038198A - A kind of closed loop expectoration method and system of automatic Titration expectoration pressure - Google Patents
A kind of closed loop expectoration method and system of automatic Titration expectoration pressure Download PDFInfo
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- CN110038198A CN110038198A CN201910375567.XA CN201910375567A CN110038198A CN 110038198 A CN110038198 A CN 110038198A CN 201910375567 A CN201910375567 A CN 201910375567A CN 110038198 A CN110038198 A CN 110038198A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M16/0006—Accessories therefor, e.g. sensors, vibrators, negative pressure with means for creating vibrations in patients' airways
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- G—PHYSICS
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- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3344—Measuring or controlling pressure at the body treatment site
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Abstract
The present invention relates to a kind of closed loop expectoration methods of automatic Titration expectoration pressure, including S1, set negative pressure phase flow rate-volume ring anchor ring product F-V anchor ring product reference point C2 of user；S2, with the actual value R2 for the negative pressure phase F-V anchor ring product for calculating user；S3 compares the reference point C2 of negative pressure phase F-V anchor ring product, negative pressure phase flow rate-volume anchor ring product actual value R2, to adjust negative pressure E-P and/or positive phase pressure I-P.The present invention also proposes a kind of closed loop expectoration system of automatic Titration expectoration pressure, comprising: reference point setting module, setting negative pressure phase flow rate-volume ring anchor ring product F-V anchor ring product reference point C2；Calculated with actual values module, monitoring and the actual value R2 for calculating negative pressure phase F-V anchor ring product；Comparison module compares reference point C2 and actual value R2；Adjustment module, based on the comparison module as a result, to adjust negative pressure E-P and positive phase pressure I-P.Expectoration method and system of the invention ensure that expectoration is more safe and effective.
Description
Technical field
The present invention relates to expectoration machines, more particularly to a kind of machinery of automated closed-loop titration expectoration pressure fills exhaust side
Method and system.
Background technique
Cough is a kind of physiological mechanism of normal person's removing respiratory airway secretion.But for certain with cough function
The patient of energy disorder disease, such as the patient that the neuromuscular disease patient of cough power decrease, mechanical ventilation are intubated, by certain
External force is just become very necessary with removing airway secretions.
Machinery fills exhaust (MI-E) device, is commonly called as expectoration machine, is that auxiliary is used to known to one kind with ineffective cough
Patient removes the device of harmful secretion in its air flue.The cough physiological mechanism of this unit simulation normal person, control and disease
Pipeline (mask connecting pin, bite connecting pin or trachea cannula connecting pin) airway pressure of people's connection is alternately being set just
(negative pressure phase) toggles between phase the blowing pressure (positive pressure phase) and setting negative pressure at expulsion.On positive the blowing pressure is slow
It rises and expands the lung of patient gradually, rapidly switch to negative pressure at expulsion then to generate the cough air-flow of high speed, thus
With the secretion in gas off-take.
The MI-E device of most representative at present and state-of-the-art commercialization is Philips Respironics company
CoughAssist T70/E70.
Patent of invention US6929007B2 discloses a kind of improved MI-E system with knocking function, which passes through
The oscillation of high frequency is added during inflating positive pressure and negative exhaust pressure to play the effect for loosening air flue sputum.This patent exists
It has been obtained in CoughAssist E70 using embodiment.
Patent of invention US2005/0039749A1 also discloses a kind of improved MI-E system, which can mutually tie in negative pressure
Pause phase after beam judges that the air-breathing of patient is exerted oneself, and the automatic synchronization triggering mutually switched to positive pressure is realized, so as to improve cough is used
Patient's expectoration of phlegm machine is experienced.The concrete application of this patent is presented as the Cough-Trak function in CoughAssist T70/E70
Energy.
Patent of invention EP1933912B1 proposes that one kind can be with the online MI-E expectoration system of ventilator cooperating, should
System judges that ventilator by the opportunity of inspiratory phase steering expiratory phase, turns determining by the sensor connecting with breathing circuit
The moment for changing opportunity arrival, the normal ventilation channel of ventilator and patient were truncated, and opened simultaneously negative between patient and expectoration machine
Suction channel is pressed, later once determining negative pressure mutually terminates opportunity arrival, the system is again automatic to restore ventilator and patient airway
Normal connection.It is in simple terms exactly that the positive phase pressure of this MI-E is controlled by ventilator, and negative pressure is controlled by expectoration machine.
All multi-risk Systems that this online MI-E expectoration system can avoid traditional sputum aspirator tube suction sputum from causing significantly, and realize non-invasively clear
Except the effect of intubated patient's air flue sputum.The concrete application of this patent is the CoughSync expectoration machine of the applicant's research and development.
Current machinery fills exhaust (MI-E) device, is all with positive negative expectoration pressure set by user for control target.
It is substantially all there are two types of expectoration mode, i.e. manual mode and automatic mode, under manual mode, the switching of positive, negative pressure is
Switch knob or remote controler are operated by user to realize；Automatic mode, is exactly timing mode in fact, and machine is set according to user
Time control positive and negative phase pressure switching time.But no matter under which kind of mode, current MI-E device is all with set by user
Positive and negative phase expectoration pressure is control target.
Generally, it is considered that expectoration pressure is higher, then the expectoration tolerance generated is bigger, cough peak flow is higher, then also more has
Conducive to the discharge of airway secretions；But expectoration pressure is higher, the risk for causing patient airway to damage is also bigger；And to Mr. Yu
The patient of a little common respiratory airway diseases (such as Chronic Obstructive Pulmonary Disease COPD, oblongata are damaged), negative expectoration pressure are higher
Air flue can instead fallen into close that expectoration effect is caused to decline.
User (doctor or patient itself) can generally rely on experience in practice, according to the different situations of patient (such as age,
The factors such as sufferer type, patient airway impedance, patient itself cough dynamics) titrate the expectoration pressure for being adapted to some given patient
Power.Manual titration's expectoration pressure is haveed the defects that following:
(1) titration expectoration pressure is a trial and error process repeatedly, and if once the state of patient is sent out after titration
Changing then still needs to repeat to titrate, this is troublesome.
(2) dependence experience titrates out by trial and error method expectoration pressure it's hard to say be it is optimal, because of titration process
In there is no one it is reliable assessment expectoration effect index as foundation.A kind of index of most common setting expectoration pressure
Be that cough peak flow will reach 160LPM (for general adult), even if but actually cough peak flow can reach
160LPM, also not necessarily can smooth expectoration sputum, reason has two: 1, certain air flues is easy to fall into the patient closed, most common
Be patient COPD, their cough peak flow is not low, but whole cough phase flow rate is but very low；2, for certain lungs
The poor patient of portion's compliance, even if expectoration peak flow is very high, but once the tolerance of cough expectoration is seldom.Both feelings
Condition all illustrates that, with single expectoration index, such as common expectoration peak flow is unsatisfactory to titrate expectoration pressure.
Summary of the invention
For that must rely on user's experience in the expectoration mode in current MIE device, trial and error titrates expectoration pressure repeatedly
Defect, the present invention proposes a kind of closed loop expectoration method of automatic Titration expectoration pressure.What the expectoration method was set with user
Negative pressure phase flow rate-volume anchor ring product is control target automatic Titration positive expectoration pressure and negative expectoration pressure.The expectoration simultaneously
The positive pressure phase flow rate that method is set with user-volume anchor ring is long-pending and negative pressure phase flow rate-volume ring ratio is controls target certainly
The dynamic acclivity for adjusting positive expectoration pressure.
The present invention proposes a kind of closed loop expectoration method of automatic Titration expectoration pressure, comprising:
S1 sets negative pressure phase flow rate-volume ring anchor ring product F-V anchor ring product reference point C2 of user；
S2, with the actual value R2 for the negative pressure phase F-V anchor ring product for calculating user；
S3, compares the reference point C2 of negative pressure phase F-V anchor ring product, and negative pressure phase flow rate-volume anchor ring product actual value R2 comes
Adjust negative pressure E-P and/or positive phase pressure I-P.
The present invention proposes a kind of closed loop expectoration method of automatic Titration expectoration pressure, comprising:
S1, user sets negative pressure phase flow rate-volume ring anchor ring product reference point C2, and sets positive/negative pressure phase flow rate-appearance
The reference ratio C 1/C2 of product ring ring area ratio；
S2 calculates positive pressure phase flow rate-volume anchor ring product actual value R1 and negative pressure phase flow rate-volume anchor ring product reality
The actual ratio R1/R2 of value R2 and the two；
S3 compares negative pressure phase flow rate-volume ring anchor ring product reference point C2 and actual value R2, to automatically adjust negative pressure
E-P, positive phase pressure I-P；
S4, more positive/negative pressure phase flow rate-volume ring ring area ratio reference ratio C 1/C2 and actual ratio R1/R2,
To automatically adjust positive pressure acclivity P-Slope.
A kind of closed loop expectoration system of automatic Titration expectoration pressure, the expectoration system include:
Reference point setting module, the reference point setting module are configured as setting negative pressure phase flow rate-volume ring anchor ring product
The reference point C2 of F-V anchor ring product；
Calculated with actual values module, the calculated with actual values module monitors and the actual value R2 for calculating negative pressure phase F-V anchor ring product；
Comparison module, the comparison module compare reference point C2 and actual value R2；
Adjustment module, the adjustment module based on the comparison module as a result, to adjust negative pressure E-P and positive pressure
Power I-P increases the negative pressure E-P and/or positive phase pressure I- of expectoration next time if reference point C2 is smaller than actual value R2
P；Conversely, then reducing.
The present invention proposes a kind of closed loop expectoration system of automatic Titration expectoration pressure, comprising:
Reference point setting module, the reference point setting module are configured as, and user can set negative pressure phase flow rate-appearance
The reference point C2 of product ring anchor ring product, and positive/negative pressure phase flow rate-volume ring ring area ratio reference point C1/C2 can be set；
Calculated with actual values module, the calculated with actual values module monitors and calculating positive pressure phase flow rate-volume anchor ring product reality
Actual value R1 and negative pressure phase flow rate-actual value R2 of the volume anchor ring product and ratio R 1/R2 of the two；
Comparison module, the comparison module compare negative pressure phase flow rate-volume ring anchor ring product reference point C2 and actual value R2,
And more positive/negative pressure phase flow rate-volume ring ring area ratio reference point C1/C2 and actual value R1/R2；
Adjustment module, the adjustment module based on the comparison module as a result, to adjust negative pressure E-P, positive pressure
Power I-P and positive pressure acclivity P-Slope.
Remote upgrade module, the cloud that the remote upgrade module can make closed loop expectoration system be connected to manufacturer take
Business device, to realize the online upload of expectoration treatment data；Cloud server is uploaded a large amount of using the expectoration machine for being dispersed in various regions
Treatment data, control algolithm that can constantly in remote upgrade closed loop expectoration controller gradually make closed loop expectoration controller
Expectoration pressure titer level meets or exceeds the degree of expert.
The closed loop expectoration method of titration expectoration pressure proposed by the present invention compared with conventional MI-E expectoration mode, have with
Lower advantage:
(1) setting of closed loop expectoration method is no longer a cumbersome process, reduces the experience dependence to user, drop
The expectoration parameter of low user titrates workload, patient specific for one, expectoration parameter once it is determined that, even if suffering from from now on
The physiological status of person changes, without titration expectoration parameter again；
(2) with F-V anchor ring product (being equivalent to air-flow momentum) this index directly corresponding with expectoration validity in expectoration
As control target, the control of expectoration is made to become intuitive, also with more the property assessed；
(3) the control rule in the controller of closed loop expectoration system can use big data obtained in actual use, into
Row constantly upgrading guarantees that expectoration is more safe and effective.
Detailed description of the invention
Fig. 1 is the working principle diagram of expectoration method of the invention.
Fig. 2 is the flow chart of expectoration method of the invention.
Fig. 3 is the frame diagram of expectoration system of the invention.
Fig. 4 is the human-computer interaction interface schematic diagram of expectoration system of the invention.
Specific embodiment
Embodiments of the present invention are described with reference to the accompanying drawings, wherein identical component is presented with like reference characters.
In the absence of conflict, the technical characteristic in following embodiment and embodiment can be combined with each other.
Fig. 1 expresses the control principle of method and system of the invention.
Starting point of the invention is the basic mechanical principle moved according to secretion: in expectoration, the average cough of negative pressure phase
The expectoration tolerance of flow and negative pressure phase must all reach certain setting value, be possible to the secretion cough in air flue effectively
Out.The movement of secretion is generated by the airflow thrust being applied to it, and the bigger secretion of thrust accelerates faster；But make
Thrust duration on secretion is also very crucial, and the time of thrust application is longer, and the move distance of secretion is also longer.
The average cough uninterrupted of negative pressure phase determines the size for acting on the airflow thrust on secretion, and negative pressure phase
Expectoration tolerance size determine the time for acting on the airflow thrust on secretion, therefore the product of the two just determines effect
In the air-flow momentum on secretion.The averagely product (being equivalent to air-flow momentum) of cough flow and expectoration tolerance is exactly institute in Fig. 1
The area of the negative pressure phase F-V ring shown.So being capable of extraordinary reflection expectoration using the area of negative pressure phase F-V ring as measurement index
Validity.
With flow-volume anchor ring product under the closed loop expectoration mode of target, the control target of user setting is no longer expectoration
Pressure, but the F-V ring area target of negative pressure phase.By taking an adult as an example, it is considered that average expectoration flow will reach
160LPM, expectoration tolerance will at least reach 1L, could be effectively by sputum expectoration, therefore the reasonable negative pressure phase F-V of a comparison
Ring area target is 160 × 1=160L2/min。
In fact, the F-V anchor ring product of negative pressure phase is not only paid close attention to, the F-V anchor ring product of positive pressure phase is also the same important, because of positive pressure
Phase airflow function in the active force of secretion be it is reversed be unfavorable for it and moved to disease population extreme direction, so if positive pressure phase
F-V anchor ring product it is excessive, will result in the secretion of negative pressure phase expectoration in positive pressure next time and mutually and blown back the knot in air flue deep
Fruit.Just because of this, in closed loop expectoration mode, the F-V ring area ratio no less important of positive/negative pressure phase is controlled.Positive pressure phase
F-V anchor ring product is necessarily less than the F-V anchor ring product of negative pressure phase, therefore sets positive/negative pressure phase F-V ring area ratio and have to less than 1,
Can between 0.3~0.8 value.
Because there are two target, i.e. negative pressure phase F-V anchor ring product and positive/negative pressure phase F-V ring area ratio is controlled, so Fig. 1
Shown in control principle include two parallel control loops.
Each control period, expectoration system all according to last time expectoration at the end of determine positive expectoration pressure I-P, negative cough
The MI-E device of control this expectoration of target control of phlegm pressure E-P, positive expectoration pressure acclivity P-slope exports pressure
Power, while monitoring and recording the flow-volume ring area change in expectoration.
If determining this expectoration a control period terminates, the actual negative pressure of this expectoration can be calculated
The ratio of phase F-V anchor ring product, actual positive pressure phase F-V anchor ring product and the two, i.e., actual positive/negative pressure phase F-V ring area ratio
Value.The actual value of monitoring is made comparisons with the setting value of user, then it can be according to certain rule or control rate (i.e. expectoration controller
The control algolithm of middle operation) adjust expectoration next time positive expectoration pressure I-P, negative expectoration pressure E-P, positive expectoration pressure
Acclivity P-slope, the target of these three parameters.
If the actual suction pressure phase F-V ring area ratio setting negative pressure phase F-V anchor ring product at the end of this expectoration is small, it should increase
The negative pumping pressure E-P or positive inflation pressure I-P of big expectoration next time；Conversely, should then reduce.
If the positive/negative pressure phase F-V anchor ring product odds ratio of reality at the end of this expectoration sets positive/negative pressure phase F-V anchor ring
Product ratio is small, it should increase the positive expectoration pressure acclivity P-slope of expectoration next time；Conversely, should then reduce.
Various expectoration controllers can be designed in practice, such as simple rule-based controller, PID control
Device perhaps fuzzy logic controller, nerve network controller or the controller based on big data rule digging.But no matter control
Which kind of device processed is, all the risk for considering that the increase of expectoration pressure will lead to should be effectively combined guaranteeing expectoration, for example, just
Phase pressure is excessively high to may cause lung's wind-contusion, and too early fall into that negative hypertonia may cause big airways is closed.
One control end cycle, into next control period.Repeat above-mentioned expectoration control process.
As shown in Figure 1, the closed loop expectoration method of automatic Titration expectoration pressure of the invention includes:
S1 sets negative pressure phase flow rate-volume ring anchor ring product reference point C2 of user.
S2, with the negative pressure phase flow rate-volume anchor ring product actual value R2 for calculating user.
S3 compares negative pressure phase flow rate-volume ring anchor ring product reference point C2, negative pressure phase flow rate-volume anchor ring product reality
Value R2, to adjust positive pressure acclivity P-Slope.Specifically, if negative pressure phase flow rate-volume ring anchor ring product reference point
C2 is smaller than the actual value R2 of negative pressure phase flow rate-volume anchor ring product, then increases the negative pressure E-P and/or positive of expectoration next time
Pressure I-P；Conversely, then reducing.In another embodiment, the closed loop expectoration side of automatic Titration expectoration pressure of the invention
Method includes:
S1 sets positive pressure phase flow rate-volume anchor ring product reference point C1 of user, negative pressure phase flow rate-volume ring anchor ring
Long-pending reference point C2 calculates positive/negative-pressure phase flow rate-volume anchor ring product reference ratio C 1/C2.
S2 calculates positive pressure phase flow rate-volume anchor ring product actual value R1 of user, negative pressure phase flow rate-volume anchor ring product
Actual value R2, calculate the actual ratio R1/R2 of positive/negative-pressure phase flow rate-volume anchor ring product.
S3 compares positive/negative-pressure phase flow rate-volume anchor ring product reference ratio C1/C2 and positive/negative-pressure phase flow rate-volume anchor ring
Long-pending actual ratio R1/R2, to adjust negative pressure E-P, positive phase pressure I-P and positive pressure acclivity P-Slope.Specifically
Ground, if the actual suction pressure phase F-V ring area ratio setting negative pressure phase F-V anchor ring product at the end of this expectoration is small, it should under increase
The negative pumping pressure E-P or positive inflation pressure I-P of expectoration；Conversely, should then reduce.If at the end of this expectoration
It is small that practical positive/negative pressure phase F-V anchor ring product odds ratio sets positive/negative pressure phase F-V ring area ratio, it should increase expectoration next time
Positive expectoration pressure acclivity P-slope；Conversely, should then reduce.
As shown in Fig. 2, in another embodiment, the closed loop expectoration method packet of automatic Titration expectoration pressure of the invention
It includes:
S1, setting negative pressure phase flow rate-volume ring anchor ring product reference point C2, and set positive/negative pressure phase flow rate-volume ring ring
The reference point C1/C2 of area ratio；
S2, each expectoration terminate, and calculate positive pressure phase flow rate-volume anchor ring product actual value R1 and negative pressure phase flow rate-volume
The actual value R2 of the anchor ring product and ratio R 1/R2 of the two；
S3 compares negative pressure phase flow rate-volume ring anchor ring product reference point C2 and actual value R2, to automatically adjust negative pressure
E-P, positive phase pressure I-P；Specifically, if negative pressure phase flow rate-volume anchor ring product actual value R2 is than negative pressure phase flow rate-volume
The reference point C2 of ring anchor ring product is small, then increases the negative pressure E-P or positive phase pressure I-P of expectoration next time；Conversely, then reducing.
S4, more positive/negative pressure phase flow rate-volume ring ring area ratio reference point C1/C2 and actual value R1/R2, comes from
It is dynamic to adjust positive pressure acclivity P-Slope；Specifically, if the positive/negative pressure phase F-V ring of reality at the end of this expectoration
Area ratio R1/R2 is smaller than setting positive/negative pressure phase F-V anchor ring product ratio C 1/C2, it should increase the positive expectoration of expectoration next time
Pressure acclivity P-slope；Conversely, should then reduce.
According to another aspect of the present invention, as shown in figure 3, proposing a kind of closed loop expectoration system, the expectoration system includes:
Reference point setting module, the reference point setting module are configured as, and user can set negative pressure phase flow rate-appearance
The reference point C2 of product ring anchor ring product, and positive/negative pressure phase flow rate-volume ring ring area ratio reference point C1/C2 can be set；
Calculated with actual values module, the calculated with actual values module monitors and calculating positive pressure phase flow rate-volume anchor ring product reality
Actual value R1 and negative pressure phase flow rate-actual value R2 of the volume anchor ring product and ratio R 1/R2 of the two；
Comparison module, the comparison module compare negative pressure phase flow rate-volume ring anchor ring product reference point C2 and actual value R2,
And more positive/negative pressure phase flow rate-volume ring ring area ratio reference point C1/C2 and actual value R1/R2；
Adjustment module, the adjustment module based on the comparison module as a result, to adjust negative pressure E-P, positive pressure
Power I-P and positive pressure acclivity P-Slope.
Remote upgrade module, the cloud that the remote upgrade module can make closed loop expectoration system be connected to manufacturer take
Business device, to realize the online upload of expectoration treatment data；Cloud server is uploaded a large amount of using the expectoration machine for being dispersed in various regions
Treatment data, control algolithm that can constantly in remote upgrade closed loop expectoration controller gradually make closed loop expectoration controller
Expectoration pressure titer level meets or exceeds the degree of expert.
Optionally, closed loop expectoration system is run in a MI-E device.One MI-E device necessarily include human-computer interaction,
Multiple modules such as expectoration pressure and flow monitoring/control, power supply, gas circuit structure, expectoration machine casing.The closed loop cough of one signal
Phlegm mode human-computer interaction interface is as shown in Figure 4.
It include the information alert column at top in human-computer interaction interface, prompting current mode as shown in Figure 4 is Intelli-
Cough expectoration mode；The lower right corner is adjusting knob or manual expectoration key；Bottom is that actions menu and expectoration are arranged parameter and show
Area, wherein expectoration parameter set by user is shown, such as negative pressure phase F-V ring area setting, positive/negative pressure phase F-V ring area ratio
Setting value；The left side dynamically shows the airway pressure in expectoration；Middle part is the viewing area of wave ring；The right is in expectoration
Actual monitoring expectoration parameter.
In the specific implementation, the basic height/weight of typing patient and disease type information can be increased in human-computer interaction
Function, neuromuscular disease in this way, obstructive disease of lung, restrictive lung disease etc., in such closed loop expectoration mode controller
The patient information that can use these typings realizes more personalized expectoration Validity control.
In the specific implementation, any patient can also be increased the preset initial value option of an expectoration pressure: is to maintain
Expectoration pressure when last time expectoration treatment end controls target component；Still the expectoration pressure for re-typing this expectoration treatment is pre-
If initial value.Such option can make closed loop expectoration mode more be able to satisfy the demand of different user.
Embodiment described above, the only present invention more preferably specific embodiment, those skilled in the art is at this
The usual variations and alternatives carried out within the scope of inventive technique scheme should be all included within the scope of the present invention.
Claims (10)
1. a kind of closed loop expectoration method of automatic Titration expectoration pressure characterized by comprising
S1 sets negative pressure phase flow rate-volume ring anchor ring product F-V anchor ring product reference point C2 of user；
S2, with the actual value R2 for the negative pressure phase F-V anchor ring product for calculating user；
S3, compares the reference point C2 of negative pressure phase F-V anchor ring product, the actual value R2 of negative pressure phase flow rate-volume anchor ring product, negative to adjust
Phase pressure E-P and/or positive phase pressure I-P.
2. closed loop expectoration method according to claim 1, which is characterized in that
In S3, if reference point C2 is smaller than actual value R2, increase the negative pressure E-P and/or positive pressure of expectoration next time
Power I-P；Conversely, then reducing.
3. closed loop expectoration method according to claim 2, which is characterized in that
In S1, the reference point C1 of the positive pressure phase F-V anchor ring product of user, the reference point C2 of negative pressure phase F-V anchor ring product are set, if
Determine the reference ratio C 1/C2 of positive/negative-pressure phase F-V anchor ring product；
In S2, the actual value R1 of the positive pressure phase F-V anchor ring product of user, the actual value R2 of negative pressure phase F-V anchor ring product, meter are calculated
Calculate the actual ratio R1/R2 of positive/negative-pressure phase F-V anchor ring product；
In S3, if at the end of this expectoration, actual ratio R1/R2 ratio is small referring to ratio C 1/C2, it should increase cough next time
The positive expectoration pressure acclivity P-slope of phlegm；Conversely, should then reduce.
4. a kind of closed loop expectoration method of automatic Titration expectoration pressure characterized by comprising
S1, sets negative pressure phase flow rate-volume ring anchor ring product F-V anchor ring product reference point C2 of user, and sets positive and negative F-V ring
The reference point C1/C2 of area ratio；
S2 calculates the actual value R1 of positive pressure phase F-V anchor ring product and the actual value R2 and ratio R 1/ of negative pressure phase F-V anchor ring product
R2；
S3 compares reference point C2 and actual value R2, to automatically adjust negative pressure E-P, positive phase pressure I-P；
S4 compares referring to ratio C 1/C2 and actual ratio R1/R2, to automatically adjust positive pressure acclivity P-Slope.
5. closed loop expectoration method according to claim 4, which is characterized in that
In S3, if actual value R2 is smaller than reference point C2, increase the negative pressure E-P or positive phase pressure I- of expectoration next time
P；Conversely, then reducing.
In S4, if actual ratio R1/R2 ratio is small referring to ratio C 1/C2 at the end of this expectoration, it should increase cough next time
The positive expectoration pressure acclivity P-slope of phlegm；Conversely, should then reduce.
6. a kind of closed loop expectoration system of automatic Titration expectoration pressure, the expectoration system include:
Reference point setting module, the reference point setting module are configured as setting negative pressure phase flow rate-volume ring anchor ring product F-V ring
The reference point C2 of area；
Calculated with actual values module, the calculated with actual values module monitors and the actual value R2 for calculating negative pressure phase F-V anchor ring product；
Comparison module, the comparison module compare reference point C2 and actual value R2；
Adjustment module, the adjustment module based on the comparison module as a result, to adjust negative pressure E-P and positive phase pressure I-
P increases the negative pressure E-P and/or positive phase pressure I-P of expectoration next time if reference point C2 is smaller than actual value R2；Instead
It, then reduce.
7. closed loop expectoration system according to claim 6, which is characterized in that
The reference point setting module is configured as, and is set the reference point C1 of the positive pressure phase F-V anchor ring product of user, is set positive and negative
Press the reference ratio C 1/C2 of phase F-V anchor ring product；
The calculated with actual values module calculates the actual value R1 of the positive pressure phase F-V anchor ring product of user, calculates positive/negative-pressure phase F-V ring
The actual ratio R1/R2 of area；
The comparison module compares referring to ratio C 1/C2 and actual ratio R1/R2；
The adjustment module based on the comparison module as a result, to adjust positive expectoration pressure acclivity P-slope, if
Actual ratio R1/R2 ratio at the end of this expectoration is small referring to ratio C 1/C2, it should increase the positive expectoration pressure of expectoration next time
Power acclivity P-slope；Conversely, should then reduce.
8. a kind of closed loop expectoration system of automatic Titration expectoration pressure, the expectoration system include:
Reference point setting module, the reference point setting module are configured as, setting negative pressure phase flow rate-volume ring anchor ring product ginseng
According to value C2, and set positive/negative pressure phase flow rate-volume ring ring area ratio reference point C1/C2；
Calculated with actual values module, the calculated with actual values module monitors and calculating positive pressure phase flow rate-volume anchor ring product actual value
R1 and negative pressure phase flow rate-actual value R2 of the volume anchor ring product and ratio R 1/R2 of the two；
Comparison module, the comparison module compares negative pressure phase flow rate-volume ring anchor ring product reference point C2 and actual value R2, and compares
Calibration/negative pressure phase flow rate-volume ring ring area ratio reference ratio C 1/C2 and actual ratio R1/R2；
Adjustment module, the adjustment module based on the comparison module as a result, to adjust negative pressure E-P, positive phase pressure I-P
With positive pressure acclivity P-Slope.
9. closed loop expectoration system according to claim 8, which is characterized in that further include:
Remote upgrade module, the remote upgrade module are connectable to cloud server, with realize expectoration treatment data
Line uploads, and receives the algorithm of cloud server update.
10. closed loop expectoration system according to claim 9, which is characterized in that reference point setting module is configured as:
The basic height of patient, weight and the disease type information of typing are received, and each reference point is arranged based on the information.
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