CN110037828A - A kind of adjustable arteria renalis windowing endovascular stent for abdominal aorta system - Google Patents

A kind of adjustable arteria renalis windowing endovascular stent for abdominal aorta system Download PDF

Info

Publication number
CN110037828A
CN110037828A CN201910300527.9A CN201910300527A CN110037828A CN 110037828 A CN110037828 A CN 110037828A CN 201910300527 A CN201910300527 A CN 201910300527A CN 110037828 A CN110037828 A CN 110037828A
Authority
CN
China
Prior art keywords
overlay film
windowing
film frame
region
arteria renalis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201910300527.9A
Other languages
Chinese (zh)
Other versions
CN110037828B (en
Inventor
李鑫
舒畅
张惟常
李抗
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Second Xiangya Hospital of Central South University
Original Assignee
Second Xiangya Hospital of Central South University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Second Xiangya Hospital of Central South University filed Critical Second Xiangya Hospital of Central South University
Priority to CN201910300527.9A priority Critical patent/CN110037828B/en
Publication of CN110037828A publication Critical patent/CN110037828A/en
Application granted granted Critical
Publication of CN110037828B publication Critical patent/CN110037828B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/954Instruments specially adapted for placement or removal of stents or stent-grafts for placing stents or stent-grafts in a bifurcation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2002/061Blood vessels provided with means for allowing access to secondary lumens

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Prostheses (AREA)

Abstract

A kind of adjustable arteria renalis windowing endovascular stent for abdominal aorta system, including for being arranged in abdominal aorta and lesion corresponding position, and the main support of external overlay film, the main support is provided with the exposed region of non-overlay film in the region where the arteria renalis of left and right, in exposed region position equipped with releasable in the main support, first windowing overlay film frame and second windowing overlay film frame of the axial length not less than exposed region size, described first, second windowing overlay film frame is equipped with non-overlay film region, overlay film region and it is arranged on overlay film region, the first windowing and the second windowing to match with arteria renalis openings of sizes, the present apparatus is easy to use, different patients are adapted to by a set of equipment, accelerate the progress for the treatment of, significantly reduce the financial burden of patient, suitable for industrial production.

Description

A kind of adjustable arteria renalis windowing endovascular stent for abdominal aorta system
Technical field
The present invention relates to a kind of adjustable arteria renalis windowing endovascular stent for abdominal aorta systems.
Background technique
Endovascular stent for abdominal aorta is widely used in clinic, energy as the intervention therapeutic apparatus for being directed to abdominal aneurvsm Effective isolation abdominal aneurvsm and the lesions such as ulcer or interlayer, form fixed alternative pipeline.In clinical use process In because different sufferer diseased regions difference, and the difference of every patient's arteria renalis aperture position, the especially close arteria renalis and Kidney mo(u)ld top half abdominal aneurvsm, so that there are certain difficulties for the intracavitary reparation of existing endovascular stent for abdominal aorta, therefore for Situation needs to customize windowing overlay film frame according to patient's arteria renalis position, but the customization period of this bracket is long, limits treatment Progress, also increase the financial burden of patient, and its operating procedure is more complicated, very to the technical requirements of doctor It is high.
Summary of the invention
The present invention proposes that one kind can adjust windowing position on demand in view of the deficiencies of the prior art, enables blood in bracket pipeline Not further into tumor chamber when flowing in road, the adjustable arteria renalis windowing endovascular stent for abdominal aorta of tumor chamber can effectively be isolated System.
The purpose of the present invention is achieved by using following technical proposals:
A kind of adjustable arteria renalis windowing endovascular stent for abdominal aorta system, including for being arranged in abdominal aorta and disease In stove corresponding position and the main support of external overlay film, the main support are provided with non-overlay film in the region where the arteria renalis of left and right Exposed region, be equipped with releasable, axial length in exposed region position in the main support and be not less than exposed region First windowing overlay film frame of size and the second windowing overlay film frame, the first, second windowing overlay film frame, which is equipped with, not to be covered Diaphragm area, overlay film region and the first windowing on overlay film region, matching with arteria renalis openings of sizes is set and second is opened After window, the first windowing overlay film frame and the second windowing overlay film frame discharge in main support, first windowing and second Open a window it is corresponding with left and right arteria renalis aperture position respectively, and it is described second windowing overlay film frame on non-overlay film region position and Non- overlay film region position is arranged with the second windowing right in first windowing position correspondence, the first windowing overlay film frame Answer, it is described first windowing overlay film frame and second windowing overlay film frame overlay film region will be opened on main support except the left and right arteria renalis The exposed region closing of mouth position.Using the above structure, on the one hand, the partial region of main support is covered with overlay film, the material of overlay film Matter has good biocompatibility, and blood effectively can be isolated, when blood being enable to flow in bracket pipeline road Not further into affected area (tumor chamber), affected area can effectively be isolated, on the other hand, pass through the exposed region on main support, energy Left and right arteria renalis aperture position effectively is avoided, does not interfere the connection of aorta Yu the left and right arteria renalis, avoids blocking blood vessel, again Have about by the first windowing overlay film frame and the second windowing overlay film frame, extexine circumference that can be discharged in main support The overlay film region in 1/3 non-overlay film region, outer surface is equipped with windowing corresponding with arteria renalis aperture position, in use, first The first windowing overlay film frame is placed, the windowing position alignment left renal artery aperture position of the first windowing overlay film frame, non-overlay film are made Region is arranged in other side right renal artery aperture position, then places the second windowing overlay film frame again, makes the second windowing overlay film branch The windowing position alignment right renal artery aperture position of frame, the overlay film region of the two, which covers blood vessel and forms substitution, to be led to Road, to pass through a set of equipment, Ke Yishi in this way for closing in main support except the exposed region of left and right arteria renalis aperture position Different patients are answered, the progress for the treatment of is accelerated, alleviate the financial burden of patient.
Further, releasable branch overlay film frame is additionally provided in the main support.
Further, the branch overlay film frame is equipped with the independent anchoring device for being fixed on target position.
Further, the first, second windowing overlay film frame opens a window on position in the first windowing and second respectively Equipped with the positioning identifier that can assist detecting the first windowing and the second windowing orientation by detection device.By positioning identifier, make Obtaining positioning identifier can develop under x-ray, and such doctor can judge the position and the situation that open a window in vivo according to the positioning identifier, Guarantee the accurate of operation.
Further, the first windowing overlay film frame and the second windowing overlay film frame are equipped with and can be fixed in main support , independent anchoring structure.
Further, the outer surface 2/3 of the first windowing overlay film frame and the second windowing overlay film frame is overlay film region, 1/3 is non-overlay film region.The diameter of first windowing and the second windowing is 6-8mm.First windowing overlay film frame and the second windowing are covered Overlay film hole is aligned according to arteria renalis aperture position, keeps the arteria renalis unobstructed by membrane support rotatably adjustable position before releasing.
Further, the main support, the first windowing overlay film frame and the second windowing overlay film frame by support skeleton and The overlay film being coated on outside support skeleton is constituted.
In conclusion the present invention it is easy to use, different patients are adapted to by a set of equipment, accelerate treatment into Degree, significantly reduces the financial burden of patient, is suitable for industrial production.
Detailed description of the invention
Fig. 1 is explosive view of the invention.
Fig. 2 is assembling figure of the present invention.
Fig. 3 is the structural representation of main support of the present invention.
Fig. 4 is the structural representation of the main first windowing overlay film frame of the present invention.
Fig. 5 is the structural representation of branch overlay film frame of the present invention.
In figure: 1, main support, the 21, first windowing overlay film frame, the 22, second windowing overlay film frame, the 23, first windowing, 3, Branch overlay film frame, 101, main support anchorage zone, 102, overlay film area on main support, 103, exposed region, 104, cover under main support Film area, 201, anchorage zone in adjusting bracket, 202, adjusting bracket overlay film, 203, adjusting bracket open a window locating piece, 204, adjust branch Anchorage zone under frame, 301, branch support skeleton, 302, branch bracket overlay film.
Specific embodiment
With reference to the accompanying drawing and specific example, it is described in detail a kind of adjustable arteria renalis windowing abdominal aorta overlay film branch The specific embodiment of frame system.
As shown in Fig. 1 to 5, a kind of adjustable arteria renalis windowing endovascular stent for abdominal aorta system, including for being arranged In abdominal aorta and lesion corresponding position and the main support 1 of external overlay film, the main support 1 is by support skeleton and is coated on Overlay film outside support skeleton is constituted, and the main support 1 is provided with the exposed region of non-overlay film in the region where the arteria renalis of left and right 103, the main support 1 is equipped with overlay film area 102 on main support above the exposed region 103, overlay film area 104 under the main support of lower section, First that releasable, axial length is not less than exposed region size is equipped in exposed region position in the main support 1 Open a window overlay film frame 21 and the second windowing overlay film frame 22, the first windowing overlay film frame 21 and the second windowing overlay film frame 22 Including support skeleton and the overlay film being coated on outside support skeleton, the first windowing overlay film frame 21 and the second windowing overlay film frame 22 include anchorage zone 204, first windowing under anchorage zone 201 and adjusting bracket in the adjusting bracket that can be fixed in main support Overlay film frame 21 and the second windowing overlay film frame 22 are equipped with non-overlay film region, overlay film region 202 and are arranged on overlay film region , with arteria renalis openings of sizes match first windowing 23 and second windowing, it is described first windowing overlay film frame and second open The outer surface 2/3 of window overlay film frame is overlay film region, and 1/3 is non-overlay film region, the first, second windowing overlay film frame difference Being equipped in the first windowing and the second windowing position can assist detecting the first windowing and the second windowing by detection device The positioning identifier 203 in orientation.By positioning identifier, positioning identifier is developed under x-ray, such doctor can be fixed according to this Position and the situation that bit identification judges to open a window in vivo, guarantee the accurate of operation.
It is described first windowing overlay film frame and second windowing overlay film frame discharge in main support after, it is described first windowing with Second windowing is corresponding with left and right arteria renalis aperture position respectively, and non-overlay film region institute is in place on the second windowing overlay film frame Non- overlay film region position on corresponding with the first windowing position, the described first windowing overlay film frame is set to exist with the second windowing setting It is corresponding, it is described first windowing overlay film frame and second windowing overlay film frame overlay film region by main support except the left and right arteria renalis The exposed region of aperture position is closed.
In the present embodiment, releasable branch overlay film frame 3 is additionally provided in the main support 1, branch overlay film frame 3 wraps Branch support skeleton 301 and branch bracket overlay film 302 are included, the branch overlay film frame is equipped with independent for being fixed on target Anchoring device on position.
Doctor is when in use: placing main support 1 according to positioning using conveyer system, the opening of the arteria renalis is made to be located at main branch Then the exposed region 103 of frame first places the first windowing overlay film frame, according to the aobvious of the windowing position of the first windowing overlay film frame Shadow positioning makes the first windowing overlay film frame windowing position alignment side arteria renalis opening, then places the second windowing overlay film branch again Frame makes the second windowing overlay film frame that replaceable channel, the second windowing overlay film branch are covered and formed to the blood vessel of the other side Windowing position alignment other side arteria renalis opening on frame, while paying attention to observation windowing positioning, in case blocking blood vessel, is finally placed Branch overlay film frame 3 after the completion of placement, is further reinforced each anchor station using sacculus, to fixed vessel diameter into The setting of one step, bracket, which is placed, to be completed.
Above-mentioned is the preferred embodiment of the present invention, but those skilled in the art should be understood that do not depart from it is appended In the spirit and scope of the present invention defined by claims, the various changes to made by the present invention in form and details Change, belongs to protection scope of the present invention.

Claims (7)

  1. The endovascular stent for abdominal aorta system 1. a kind of adjustable arteria renalis opens a window, it is characterised in that: including for being arranged in abdomen In aorta and lesion corresponding position and the main support of external overlay film, the main support are set in the region where the arteria renalis of left and right It is equipped with the exposed region of non-overlay film, is equipped in exposed region position that releasable, axial length is not small in the main support In the first windowing overlay film frame and the second windowing overlay film frame of exposed region size, the first, second windowing overlay film frame Be equipped with non-overlay film region, overlay film region and be arranged in it is on overlay film region, opened with arteria renalis openings of sizes matches first After window and the second windowing, the first windowing overlay film frame and the second windowing overlay film frame discharge in main support, described first Windowing and the second windowing are corresponding with left and right arteria renalis aperture position respectively, and non-overlay film region on the second windowing overlay film frame Position with first windowing position it is corresponding, it is described first windowing overlay film frame on non-overlay film region position with second open a window Be arranged in correspondence, it is described first windowing overlay film frame and second windowing overlay film frame overlay film region by main support except left and right The exposed region of arteria renalis aperture position is closed.
  2. The endovascular stent for abdominal aorta system 2. the adjustable arteria renalis according to claim 1 opens a window, it is characterised in that: institute It states and is additionally provided with releasable branch overlay film frame in main support.
  3. The endovascular stent for abdominal aorta system 3. the adjustable arteria renalis according to claim 2 opens a window, it is characterised in that: institute Branch overlay film frame is stated equipped with the independent anchoring device for being fixed on target position.
  4. 4. according to claim 1 to the windowing endovascular stent for abdominal aorta system of the adjustable arteria renalis described in one of 3, feature Be: the first, second windowing overlay film frame is equipped in the first windowing and the second windowing position respectively can pass through inspection Measurement equipment auxiliary detects the positioning identifier of the first windowing and the second windowing orientation.
  5. The endovascular stent for abdominal aorta system 5. the adjustable arteria renalis according to claim 4 opens a window, it is characterised in that: institute State the first windowing overlay film frame and second windowing overlay film frame be equipped with can be fixed in main support, independent anchoring structure.
  6. The endovascular stent for abdominal aorta system 6. the adjustable arteria renalis according to claim 4 opens a window, it is characterised in that: institute The outer surface 2/3 for stating the first windowing overlay film frame and the second windowing overlay film frame is overlay film region, and 1/3 is non-overlay film region.
  7. The endovascular stent for abdominal aorta system 7. the adjustable arteria renalis according to claim 4 opens a window, it is characterised in that: institute Main support, the first windowing overlay film frame and the second windowing overlay film frame are stated by support skeleton and is coated on covering outside support skeleton Film is constituted.
CN201910300527.9A 2019-04-15 2019-04-15 Adjustable renal artery fenestration abdominal aorta tectorial membrane support system Active CN110037828B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910300527.9A CN110037828B (en) 2019-04-15 2019-04-15 Adjustable renal artery fenestration abdominal aorta tectorial membrane support system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910300527.9A CN110037828B (en) 2019-04-15 2019-04-15 Adjustable renal artery fenestration abdominal aorta tectorial membrane support system

Publications (2)

Publication Number Publication Date
CN110037828A true CN110037828A (en) 2019-07-23
CN110037828B CN110037828B (en) 2023-12-22

Family

ID=67277280

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910300527.9A Active CN110037828B (en) 2019-04-15 2019-04-15 Adjustable renal artery fenestration abdominal aorta tectorial membrane support system

Country Status (1)

Country Link
CN (1) CN110037828B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112190297A (en) * 2020-10-13 2021-01-08 复旦大学附属中山医院 Adaptive modular occlusion device special for promoting thrombosis of aortic dissection false lumen

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP083597A0 (en) * 1997-12-10 1998-01-08 William A Cook Australia Pty Ltd Endoluminal aortic stents
CN1867301A (en) * 2003-10-10 2006-11-22 威廉A·库克澳大利亚有限公司 Fenestrated stent grafts
CN202554170U (en) * 2012-02-20 2012-11-28 郗二平 Covered stent for minimally invasive interventional therapy for lesion of descending part of aortic arch of patient
US20130218258A1 (en) * 2010-05-31 2013-08-22 Po-Jen Ko Abdominal Aortic Stent
CN104398319A (en) * 2014-12-11 2015-03-11 北京华脉泰科医疗器械有限公司 Aorta abdominalis covered stent
CN204709075U (en) * 2015-06-23 2015-10-21 田玉龙 Integral type thoracic aortic branch support
CN105030372A (en) * 2015-08-31 2015-11-11 东华大学 Local gradient structure vascular stent membrane oriented to in-situ fenestration and preparation method of local gradient structure vascular stent membrane
CN205286610U (en) * 2016-01-08 2016-06-08 朱建成 Aorta covered stent
CN107119371A (en) * 2017-06-14 2017-09-01 东华大学 Orthotopic fenestration local stiffening tubing overlay film and preparation method thereof

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP083597A0 (en) * 1997-12-10 1998-01-08 William A Cook Australia Pty Ltd Endoluminal aortic stents
CN1867301A (en) * 2003-10-10 2006-11-22 威廉A·库克澳大利亚有限公司 Fenestrated stent grafts
US20130218258A1 (en) * 2010-05-31 2013-08-22 Po-Jen Ko Abdominal Aortic Stent
CN202554170U (en) * 2012-02-20 2012-11-28 郗二平 Covered stent for minimally invasive interventional therapy for lesion of descending part of aortic arch of patient
CN104398319A (en) * 2014-12-11 2015-03-11 北京华脉泰科医疗器械有限公司 Aorta abdominalis covered stent
CN204709075U (en) * 2015-06-23 2015-10-21 田玉龙 Integral type thoracic aortic branch support
CN105030372A (en) * 2015-08-31 2015-11-11 东华大学 Local gradient structure vascular stent membrane oriented to in-situ fenestration and preparation method of local gradient structure vascular stent membrane
CN205286610U (en) * 2016-01-08 2016-06-08 朱建成 Aorta covered stent
CN107119371A (en) * 2017-06-14 2017-09-01 东华大学 Orthotopic fenestration local stiffening tubing overlay film and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112190297A (en) * 2020-10-13 2021-01-08 复旦大学附属中山医院 Adaptive modular occlusion device special for promoting thrombosis of aortic dissection false lumen

Also Published As

Publication number Publication date
CN110037828B (en) 2023-12-22

Similar Documents

Publication Publication Date Title
US20110264184A1 (en) Sleeve and tubing device for restricting and constricting aneurysms and a system and method for using such a device
WO2008034341A1 (en) Duct stent being capable of carrying the subminiature radioactive particle source
CN104905892B (en) Integrated multiple branch intervenes arch of aorta overlay film frame
CN106109056B (en) A kind of multi-cavity overlay film frame and its application method
CN110393605B (en) Aortic arch area branch tectorial membrane support blood vessel composite set
CN106659357A (en) Ultrathin endoscope auxiliary system and method of use
CN203677329U (en) Novel bracket releasing device
WO2019101075A1 (en) Aortic endovascular shunt device
CN110037828A (en) A kind of adjustable arteria renalis windowing endovascular stent for abdominal aorta system
CN107280808A (en) Induction system and overlay film system
WO2019205599A1 (en) Ascending aortic stent graft
CN112842619A (en) Bow covered stent and covered stent conveyor
Pellino et al. Squamous cell carcinoma of the anal transitional zone after ileal pouch surgery for ulcerative colitis: systematic review and treatment perspectives
WO2020052185A1 (en) Ascending aorta stent anchored by innominate artery for dissection, and delivery system
CN104434354B (en) Stent placement device
CN214857826U (en) Bow covered stent and covered stent conveyor
CN107080609A (en) A kind of gatherer and its application method suitable for intestinal stent
CN208990017U (en) A kind of constant pressure expansion pipe
CN210204984U (en) Adjustable renal artery windowing abdominal aorta covered stent system
EP3946152A1 (en) Supra aortic access modular stent assembly and method
WO2022078409A1 (en) Covered stent
CN215130877U (en) Trunk support assembly capable of shortening cycle time and trunk support implantation system
CN2726558Y (en) Aortic arch type stent-graft
Ulin et al. Current views related to management of large bowel obstruction caused by carcinoma of the colon
CN210130977U (en) Semi-coated stomach and gallbladder anastomosis bracket

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant