CN110037700B - Method and device for acquiring composite gating signal and magnetic resonance equipment - Google Patents

Method and device for acquiring composite gating signal and magnetic resonance equipment Download PDF

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CN110037700B
CN110037700B CN201910398982.7A CN201910398982A CN110037700B CN 110037700 B CN110037700 B CN 110037700B CN 201910398982 A CN201910398982 A CN 201910398982A CN 110037700 B CN110037700 B CN 110037700B
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gating
respiratory
electrocardio
periods
period
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CN110037700A (en
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李海泉
薛伟霖
左红
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Neusoft Medical Systems Co Ltd
Shanghai Neusoft Medical Technology Co Ltd
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Shanghai Neusoft Medical Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/004Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
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    • A61B5/7271Specific aspects of physiological measurement analysis
    • A61B5/7285Specific aspects of physiological measurement analysis for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal
    • A61B5/7289Retrospective gating, i.e. associating measured signals or images with a physiological event after the actual measurement or image acquisition, e.g. by simultaneously recording an additional physiological signal during the measurement or image acquisition
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/30Assessment of water resources

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Abstract

The application discloses a method and a device for acquiring a composite gating signal and magnetic resonance equipment, wherein the composite gating signal which can be used for triggering magnetic resonance imaging of a heart is acquired by comprehensively utilizing a respiratory gating signal and an electrocardiographic gating signal. The method can screen out the collectable electrocardio gating signals in the respiratory stationary phase to be used as a composite gating signal for triggering the cardiac magnetic resonance imaging. The composite gating signals are obtained in the respiratory stationary phase, and the heart is in a diastolic state in the respiratory stationary phase, so that the acquired composite gating signals are used for triggering the magnetic resonance imaging of the heart, cardiac motion artifacts caused by respiratory activity can be reduced, and imaging quality is improved.

Description

Method and device for acquiring composite gating signal and magnetic resonance equipment
Technical Field
The present application relates to the field of magnetic resonance imaging technologies, and in particular, to a method and an apparatus for acquiring a composite gating signal, and a magnetic resonance device.
Background
In the medical field, when performing magnetic resonance imaging of the heart, the imaging quality is often affected by the heart motion of the subject. There are two main causes of heart motion, one is spontaneous beating of the heart and the other is respiratory activity by the subject, such as diastole or systole of the ventricles during breathing. When the magnetic resonance device scans and images the heart, the imaging has the problems of artifacts and the like due to the heart movement of a tested person.
Disclosure of Invention
In order to solve the technical problems in the prior art, the application provides a method and a device for acquiring a composite gating signal and magnetic resonance equipment, which can eliminate the influence of respiratory motion on cardiac imaging, reduce motion artifacts and improve cardiac imaging quality.
In a first aspect, the present application provides a method for acquiring a composite gating signal, including:
obtaining an electrocardio gating period reference value by using an electrocardio gating signal, and obtaining a respiration gating period reference value by using a respiration gating signal;
in the period of each respiratory gating signal, starting timing from the initial moment of the respiratory stationary phase of the respiratory gating signal, and obtaining the falling edge moment of each electrocardiograph gating signal;
obtaining a first difference value of the respiratory gating period reference value and the gating delay time;
judging whether the difference between the first difference value and the falling edge moment of the electrocardio gating signal is larger than or equal to the electrocardio gating period reference value or not;
if yes, the electrocardio gating signal is sent to a controller of magnetic resonance equipment; and if not, discarding the electrocardio gating signal.
Optionally, obtaining the reference value of the electrocardiographic gating period by using the electrocardiographic gating signal specifically includes:
acquiring electrocardio gating signals corresponding to N periods, obtaining N electrocardio gating periods, obtaining the longest electrocardio gating period from the N electrocardio gating periods, and taking the longest electrocardio gating period as the electrocardio gating period reference value; and N is a positive integer.
Optionally, obtaining the reference value of the electrocardiographic gating period by using the electrocardiographic gating signal specifically includes:
collecting electrocardio gating signals corresponding to N periods to obtain N electrocardio gating periods, removing the maximum value and the minimum value of the electrocardio gating periods from the N electrocardio gating periods to obtain the average value of the rest N-2 electrocardio gating periods, and taking the average value of the N-2 electrocardio gating periods as the electrocardio gating period reference value; and N is a positive integer greater than 2.
Optionally, the respiratory gating signal is used to obtain a respiratory gating period reference value, which specifically includes:
collecting respiratory gating signals corresponding to N periods, obtaining N respiratory gating periods, obtaining a shortest respiratory gating period from the N respiratory gating periods, and taking the shortest respiratory gating period as a respiratory gating period reference value; and N is a positive integer.
Optionally, the respiratory gating signal is used to obtain a respiratory gating period reference value, which specifically includes:
collecting respiratory gating signals corresponding to N periods to obtain N respiratory gating periods, removing the maximum value and the minimum value of the respiratory gating periods from the N respiratory gating periods to obtain the average value of the remaining N-2 respiratory gating periods, and taking the average value of the N-2 respiratory gating periods as the respiratory gating period reference value; and N is a positive integer greater than 2.
Optionally, the method further comprises: and obtaining the initial moment of the respiratory plateau of the respiratory gating signal by using the rising edge and the gating delay time of the respiratory gating signal.
In a second aspect, the present application provides an apparatus for acquiring a composite gate signal, including:
the first acquisition module is used for acquiring an electrocardio gating period reference value by utilizing an electrocardio gating signal;
the second acquisition module is used for acquiring a respiratory gating period reference value by utilizing the respiratory gating signal;
the falling edge time acquisition module is used for starting timing from the initial time of the respiratory stability period of the respiratory gating signal in the period of each respiratory gating signal to acquire the falling edge time of each electrocardiograph gating signal;
the first difference value acquisition module is used for acquiring a first difference value of the respiratory gating period reference value and the gating delay time;
the judging module is used for judging whether the difference between the first difference value and the falling edge moment of the electrocardio gating signal is larger than or equal to the electrocardio gating period reference value or not;
if yes, the signal sending module is used for sending the electrocardio gating signal to a controller of the magnetic resonance equipment; and if not, the signal discarding module is used for discarding the electrocardio gating signal.
Optionally, the period reference value first obtaining module specifically includes:
the first acquisition unit is used for acquiring the electrocardio gating signals corresponding to the N periods, acquiring N electrocardio gating periods, acquiring the longest electrocardio gating period from the N electrocardio gating periods, and taking the longest electrocardio gating period as the electrocardio gating period reference value; and N is a positive integer.
Optionally, the period reference value first obtaining module specifically includes:
the second acquisition unit is used for acquiring the electrocardio gating signals corresponding to the N periods, obtaining N electrocardio gating periods, removing the maximum value and the minimum value of the electrocardio gating periods from the N electrocardio gating periods, obtaining the average value of the rest N-2 electrocardio gating periods, and taking the average value of the N-2 electrocardio gating periods as the electrocardio gating period reference value; and N is a positive integer greater than 2.
Optionally, the second module for obtaining the period reference value specifically includes:
the third acquisition unit is used for acquiring respiratory gating signals corresponding to N periods, obtaining N respiratory gating periods, obtaining the shortest respiratory gating period from the N respiratory gating periods, and taking the shortest respiratory gating period as the respiratory gating period reference value; and N is a positive integer.
Optionally, the second module for obtaining the period reference value specifically includes:
a fourth obtaining unit, configured to collect respiratory gating signals corresponding to N periods, obtain N respiratory gating periods, reject a maximum value and a minimum value of the respiratory gating periods from the N respiratory gating periods, obtain an average value of the remaining N-2 respiratory gating periods, and use the average value of the N-2 respiratory gating periods as the respiratory gating period reference value; and N is a positive integer greater than 2.
Optionally, the apparatus further includes:
and the initial time determining module is used for obtaining the initial time of the respiratory stability period of the respiratory gating signal by utilizing the rising edge and the gating delay time of the respiratory gating signal.
In a third aspect, the application provides a magnetic resonance apparatus comprising: a controller, and the acquisition device provided in the second aspect;
the controller is used for receiving the electrocardio gating signals sent by the acquisition device and controlling the magnetic resonance equipment to perform magnetic resonance imaging according to the electrocardio gating signals.
Compared with the prior art, the application has at least the following advantages:
the application comprehensively utilizes the respiratory gating signal and the electrocardio gating signal to obtain the composite gating signal which can be used for triggering the magnetic resonance imaging of the heart. The method screens the electrocardio gating signals in the respiratory stationary phase in the period of each respiratory gating signal: for any one of the electrocardio gating signals in the respiratory stationary phase, if the difference between the respiratory gating period reference value and the first difference of the gating delay time and the falling edge moment of the electrocardio gating signal is larger than or equal to the electrocardio gating period reference value, the time for acquiring the electrocardio gating signal can be determined to be sufficient, and therefore, the electrocardio gating signal is sent to a controller of the magnetic resonance equipment; the difference between the first difference and the falling edge time of the electrocardio gating signal is smaller than the electrocardio gating period reference value, so that the time for collecting the electrocardio gating signal is insufficient, and the electrocardio gating signal is discarded.
The method can screen out the collectable electrocardio gating signals in the respiratory stationary phase to be used as a composite gating signal for triggering the cardiac magnetic resonance imaging. In the method, the composite gating signals are all obtained in the respiratory stationary phase, and the heart is in the diastolic state in the respiratory stationary phase, so that the acquired composite gating signals are used for triggering the magnetic resonance imaging of the heart, the heart motion artifact caused by respiratory activity can be reduced, and the imaging quality is improved.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present application, and other drawings may be obtained according to the drawings without inventive effort for a person skilled in the art.
Fig. 1 is a flowchart of a method for acquiring a composite gate control signal according to an embodiment of the present application;
fig. 2a is a schematic diagram of pre-learning for obtaining a composite gating signal according to an embodiment of the present application;
FIG. 2b is a schematic diagram of a respiratory gating signal, an electrocardiographic gating signal, and a composite gating signal after a pre-learning phase according to an embodiment of the present application;
fig. 3 is a schematic structural diagram of an apparatus for acquiring a composite gate control signal according to an embodiment of the present application;
fig. 4 is a schematic structural diagram of a magnetic resonance apparatus according to an embodiment of the present application;
fig. 5 is a functional schematic diagram of a magnetic resonance apparatus according to an embodiment of the present application.
Detailed Description
Currently, the effects of respiratory motion on cardiac coronary imaging can be controlled using electrocardiographic triggering techniques in combination with navigator echo techniques.
The electrocardio triggering technology delays for a period of time after the peak of the R wave is detected, and the magnetic resonance sequence carries out radio frequency excitation and signal acquisition in the mid-diastole of the ventricle. The heart is now relatively stationary, and motion artifacts may be reduced. Electrocardiographic triggering techniques may be used to perform morphological examinations of the heart. The navigator echo technique uses diaphragm position information to trigger imaging by acquiring echo signals to monitor changes in diaphragm position under the free breathing face in real time. The method uses a gradient echo sequence to collect echo signals at different moments and reconstructs images of the changes of the diaphragm position along with respiration according to time arrangement. When the diaphragm is in the end-of-breath position, acquisition of sequence signals is allowed to trigger magnetic resonance imaging.
However, the combined method of the electrocardiographic triggering technology and the navigator echo technology has high requirements on the system. In practical application, the implementation difficulty is high. Based on the above, the inventor provides an easy-to-realize method for improving imaging quality, which solves the problem of artifacts caused by heart motion in cardiac imaging. The method for acquiring the composite gating signal comprehensively utilizes the respiratory gating signal and the electrocardio gating signal to acquire the composite gating signal for triggering the magnetic resonance imaging of the heart. Because the composite gating signals are obtained through screening in the respiratory stationary phase and meet the time requirement of being capable of being acquired, the acquired composite gating signals are utilized to trigger the magnetic resonance imaging of the heart, so that the cardiac motion artifact caused by respiratory activity can be reduced, and the imaging quality is improved.
In order to make the present application better understood by those skilled in the art, the following description will clearly and completely describe the technical solutions in the embodiments of the present application with reference to the accompanying drawings, and it is apparent that the described embodiments are only some embodiments of the present application, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
Method embodiment one:
referring to fig. 1, the flowchart of a method for acquiring a composite gating signal according to an embodiment of the present application is shown.
As shown in fig. 1, the method for acquiring a composite gating signal provided by the present application includes:
step 101: and obtaining an electrocardio gating period reference value by using an electrocardio gating signal, and obtaining a respiration gating period reference value by using a respiration gating signal.
In the embodiment of the application, the electrocardio gating period reference value and the respiration gating period reference value are comprehensively adopted to screen and obtain the composite gating signal. The reference value of the electrocardio gating period can be obtained through learning a historical electrocardio gating signal; the breath-gating reference value may also be obtained by learning a historical breath-gating signal.
Exemplary implementations for acquiring an electrocardiographic gating period reference value and acquiring a respiratory gating period reference value are provided below, respectively.
(1) Obtaining an electrocardiographic gating period reference value
The implementation mode is as follows: acquiring electrocardio gating signals corresponding to N periods to obtain N electrocardio gating periods, obtaining the longest electrocardio gating period from the N electrocardio gating periods, and taking the longest electrocardio gating period as an electrocardio gating period reference value; n is a positive integer.
In this embodiment, the remaining acquisition time of each of the cardiac gating signals is then compared with the cardiac gating period reference value, and if the acquisition time is smaller than the cardiac gating period reference value, the cardiac gating signals are filtered out. In the implementation manner, the longest electrocardio gating period is obtained from the N electrocardio gating periods and is used as an electrocardio gating period reference value, namely, the electrocardio gating signals with insufficient residual acquisition time are screened out as far as possible, the failure of the retained electrocardio gating signals to trigger cardiac magnetic resonance imaging is avoided, and the success rate of cardiac data acquisition is improved.
The implementation mode II is as follows: collecting the electrocardio gating signals corresponding to the N periods to obtain N electrocardio gating periods, removing the maximum value and the minimum value of the electrocardio gating periods from the N electrocardio gating periods to obtain the average value of the remaining N-2 electrocardio gating periods, and taking the average value of the N-2 electrocardio gating periods as an electrocardio gating period reference value; n is a positive integer greater than 2.
In this implementation, the maximum value and the minimum value of the cardiac gating period are removed from the N cardiac gating periods, that is, the maximum value and the minimum value are regarded as abnormal values which are not representative, and the maximum value and the minimum value are not considered. The average value of the N-2 electrocardio gating periods is used as an electrocardio gating period reference value by calculating the average value of the remaining N-2 electrocardio gating periods, so that the electrocardio gating period reference value has stronger applicability in later use and has practical reference value.
(2) Obtaining respiratory gating period reference values
The implementation mode is as follows: collecting respiration gating signals corresponding to N periods to obtain N respiration gating periods, obtaining the shortest respiration gating period from the N respiration gating periods, and taking the shortest respiration gating period as a respiration gating period reference value; n is a positive integer.
In this embodiment, the remaining acquisition time of each cardiac gating signal in the respiratory stationary phase is calculated according to the respiratory gating period reference value, the remaining acquisition time is compared with the cardiac gating period reference value, and if the remaining acquisition time is greater than or equal to the cardiac gating period reference value, the cardiac gating signal is screened to be used as a composite gating signal. In the implementation manner, the shortest respiratory gating period is obtained from the N respiratory gating periods and used as a respiratory gating period reference value, namely, the residual acquisition time of the screened electrocardio gating signals is ensured to be relatively sufficient as far as possible, the failure of triggering cardiac magnetic resonance imaging by the reserved electrocardio gating signals is avoided, and the success rate of cardiac data acquisition is improved.
The implementation mode II is as follows: collecting respiration gating signals corresponding to N periods to obtain N respiration gating periods, removing the maximum value and the minimum value of the respiration gating periods from the N respiration gating periods to obtain the average value of the remaining N-2 respiration gating periods, and taking the average value of the N-2 respiration gating periods as a respiration gating period reference value; n is a positive integer greater than 2.
In this implementation, the maximum value and the minimum value of the breath gating period are removed from the N breath gating periods, that is, the maximum value and the minimum value are taken as abnormal values which are not representative, and the maximum value and the minimum value are not considered. The average value of the N-2 respiration gating periods is used as the respiration gating period reference value by calculating the average value of the remaining N-2 respiration gating periods, so that the respiration gating period reference value has stronger applicability in later use and has practical reference value.
It will be appreciated that both the electrocardiographic gating period reference value and the respiratory gating period reference value may be obtained through learning of historical data. In practical applications, other implementations than the above examples may be used to obtain the reference value of the cardiac gating period and the reference value of the respiratory gating period, respectively. Therefore, in this embodiment, the specific implementation manner of obtaining the reference value of the cardiac gating period and obtaining the reference value of the respiratory gating period is not limited.
For ease of understanding, the following steps of the present embodiment are described and illustrated below in conjunction with fig. 2a and 2 b. Fig. 2a is a schematic diagram of pre-learning for obtaining a composite gating signal according to an embodiment of the present application. Referring to fig. 2b, a schematic diagram of the respiratory gating signal, the electrocardiographic gating signal, and the composite gating signal after the pre-learning phase of fig. 2a is shown.
As illustrated in fig. 2a, in this embodiment, the reference value of the cardiac gating period may be obtained by an cardiac gating signal acquired in a pre-learning phase, and the reference value of the respiratory gating period may be obtained by a respiratory gating signal acquired in the pre-learning phase. In this embodiment, the reference value of the cardiac gating period and the reference value of the respiratory gating period applied in the step 102 and the subsequent steps are obtained by learning the history data. It will be appreciated that the pre-learned electrocardiographic gating period reference value and the respiratory gating period reference value may both be updated in real time over time.
Step 102: and in the period of each respiratory gating signal, starting timing from the initial moment of the respiratory stability period of the respiratory gating signal, and obtaining the falling edge moment of each electrocardio gating signal.
A breath plateau refers to a period of time during which breathing is relatively smooth within one cycle of the breath-gated signal. Generally, the respiratory plateau corresponds to the relative rest time of the heart. In practical applications, the respiratory gating signal often has a surge period and a breath plateau, i.e. the surge period is corresponding with a gating delay time TD, during which the breath is not stationary. Therefore, in this embodiment, in the respiratory plateau period corresponding to each respiratory gating signal, the end time of the gating delay time is taken as the start time of the respiratory plateau period, and the rising edge time of the next respiratory gating signal is taken as the end time of the respiratory plateau period. As shown in fig. 2a and 2 b. It will be appreciated that in practice, the breath plateau may also be selected according to the requirements, for example, the end of the breath plateau is set to a point in time before the rising edge of the next breath-gating signal. Therefore, the starting time and the ending time of the breath hold period are not limited in this embodiment.
In fig. 2a and 2b, there are three electrocardiographic gating signals during the respiratory plateau. T_nono1, t_nono2 and t_nono3 represent rising edge timings of the three electrocardiographic gating signals, respectively, which are timed from the initial timing of the respiratory plateau. td represents the pulse width of the electrocardiographic gating signal, which is the duration of the high level after the rising edge of the electrocardiographic gating signal is detected.
In this embodiment td is constant. Taking the first one of the three electrocardiographic gating signals in the time sequence direction as an example, the falling edge time, i.e. t_now1+td, can be obtained according to the rising edge time and the pulse width td.
Step 103: and obtaining a first difference value of the respiratory gating period reference value and the gating delay time.
In fig. 2b, tr_resp and tr_ecg represent a respiratory gating period reference value and an electrocardiographic gating period reference value, respectively, and TD represents a gating delay time. In fig. 2b, the first difference value may be denoted tr_resp-TD.
It should be noted that, in this embodiment, the respiratory gating period reference value and the electrocardiographic gating period reference value are both time lengths, and the respiratory gating period reference value and the electrocardiographic gating period reference value do not have a fixed start point and an end point. In fig. 2b, the time point after the rising edge of the respiratory gating signal passes through the gating delay time TD is taken as the starting point of the respiratory gating period reference value tr_resp, and the rising edge of a certain electrocardiograph gating signal is taken as the electrocardiograph gating period reference value tr_ecg, which are respectively convenient for viewing and understanding when the following time length comparison is performed. Therefore, the start point and the end point of the respiratory gating period reference value and the electrocardiographic gating period reference value are not limited herein.
Step 104: judging whether the difference between the first difference and the falling edge moment of the electrocardio gating signal is larger than or equal to the electrocardio gating period reference value, and if so, executing step 105; if not, step 106 is performed.
The difference between the first difference and the time of the falling edge of the electrocardiographic gating signal may be denoted as tr_resp-TD- (t_nonwi+td). Where t_nwi represents the rising edge time of the cardiac gating signal during the respiratory plateau. It should be noted that i in t_nwi may take different values or symbols for distinguishing the rising time of different electrical gating signals. For example, t_nono1, t_nono2, t_nono3, and the like. For the three electrocardiographic gating signals during the breath plateau in fig. 2b, the difference between the first difference and their respective falling edge moments is expressed as: t1, T2 and T3. Wherein T1, T2 and T3 are represented by the following formulas (1) to (3), respectively.
t1=tr_resp-TD- (t_nono1+td) formula (1)
t2=tr_resp-TD- (t_nonw2+td) formula (2)
t3=tr_resp-TD- (t_nonw3+td) formula (3)
In this embodiment, the difference between the first difference and the time of the falling edge of the electrocardiographic gating signal may be understood as the remaining acquisition time of the electrocardiographic gating signal. If the residual acquisition time is greater than or equal to the reference value of the electrocardio gating period, the method can determine that the electrocardio gating signal can be completely acquired within the residual acquisition time; if the residual acquisition time is smaller than the reference value of the electrocardio gating period, the fact that the electrocardio gating signal cannot be acquired completely in the residual acquisition time can be determined.
Step 105: and sending the electrocardio gating signals with the difference between the first difference value and the falling edge time of the electrocardio gating signals being larger than or equal to the electrocardio gating period reference value to a controller of the magnetic resonance equipment.
Taking the example shown in fig. 2b as an example, it is obvious that both T1 and T2 are larger than the reference value tr_ecg of the electrocardiographic gating signal, and thus, the electrocardiographic gating signals corresponding to each of T1 and T2 can be completely acquired. In fig. 2b, the cardiac gating signals that can be fully acquired are filled with shadows, and the cardiac gating signals that cannot be fully acquired are not filled with shadows. The electrocardiographic gating signals filled with shadows and unfilled shadows are distinguished from each other. It can be seen from the composite gating signal that the shadow filled electrocardiographic gating signal is filtered out and retained, while the shadow not filled electrocardiographic gating signal is filtered out.
The screened and retained electrocardiographic gating signals can be finally used as composite gating signals to be sent to a controller of the magnetic resonance equipment, so that the controller can perform magnetic resonance imaging on the heart according to triggering of the composite gating signals.
Step 106: and discarding the electrocardio gating signals of which the difference between the first difference value and the falling edge time of the electrocardio gating signals is smaller than the reference value of the electrocardio gating period.
Taking the example shown in fig. 2b as an example, it is obvious that T3 is smaller than tr_ecg, and therefore, the electrocardiographic gating signal corresponding to T3 cannot be completely acquired, and thus, is discarded and cannot be reflected in the composite gating signal.
The method for acquiring the composite gating signal provided by the embodiment of the application comprehensively screens all the electrocardio gating signals in the respiratory stationary phase according to the respiratory gating signals and the electrocardio gating signals, screens and discards the electrocardio gating signals with insufficient residual acquisition time, thereby ensuring the acquisition success rate of cardiac data when the composite gating signals are used for triggering the magnetic resonance imaging of the heart. In the method, the composite gating signals are all obtained in the respiratory stationary phase, and the heart is in the diastolic state in the respiratory stationary phase, so that the acquired composite gating signals are used for triggering the magnetic resonance imaging of the heart, the heart motion artifact caused by respiratory activity can be reduced, and the imaging quality is improved.
In addition, in the method provided in the foregoing embodiment, before the step 102 is performed, the method may further include:
and obtaining the initial moment of the respiratory plateau of the respiratory gating signal by using the rising edge and the gating delay time of the respiratory gating signal.
As shown in fig. 2b, the moment reached after a delay of the gating delay time TD from one rising edge is the initial moment of the respiratory plateau in the respiratory gating period.
After the initial moment of the respiratory stationary phase is determined through the step, the screening of the electrocardio gating signals with the residual acquisition time meeting the requirement from the moment is facilitated.
Based on the method for acquiring the composite gating signal provided by the foregoing embodiment, correspondingly, the application further provides a device for acquiring the composite gating signal. Specific implementations of the apparatus are described and illustrated below in conjunction with the embodiments and figures.
Device embodiment
Referring to fig. 3, the structure of an apparatus for acquiring a composite gate signal according to an embodiment of the present application is shown.
As shown in fig. 3, an apparatus for acquiring a composite gating signal according to an embodiment of the present application includes:
the device comprises a period reference value first acquisition module 301, a period reference value second acquisition module 301, a falling edge moment acquisition module 303, a first difference value acquisition module 304, a judgment module 305, a signal transmission module 306 and a signal discarding module 307.
The functions of the respective modules are described below.
The first acquisition module 301 is configured to obtain an electrocardiographic gating period reference value by using an electrocardiographic gating signal;
a period reference value second obtaining module 302, configured to obtain a respiratory gating period reference value by using the respiratory gating signal;
a falling edge time acquisition module 303, configured to start timing from an initial time of a respiratory plateau of the respiratory gating signal in a period of each respiratory gating signal, to obtain a falling edge time of each electrocardiograph gating signal;
a first difference obtaining module 304, configured to obtain a first difference between the respiratory gating period reference value and a gating delay time;
a judging module 305, configured to judge whether a difference between the first difference and a falling edge time of the electrocardiographic gating signal is greater than or equal to the electrocardiographic gating period reference value;
if so, the signal sending module 306 is configured to send the electrocardiographic gating signal to a controller of the magnetic resonance device; if not, the signal discarding module 307 is configured to discard the electrocardiographic gating signal.
The device provided by the application comprehensively utilizes the respiratory gating signal and the electrocardio gating signal to obtain the composite gating signal which can be used for triggering the magnetic resonance imaging of the heart. The device screens the electrocardio gating signals in a respiratory stationary phase in the period of each respiratory gating signal: for any one of the electrocardio gating signals in the respiratory stationary phase, if the difference between the respiratory gating period reference value and the first difference of the gating delay time and the falling edge moment of the electrocardio gating signal is larger than or equal to the electrocardio gating period reference value, the time for acquiring the electrocardio gating signal can be determined to be sufficient, and therefore, the electrocardio gating signal is sent to a controller of the magnetic resonance equipment; the difference between the first difference and the falling edge time of the electrocardio gating signal is smaller than the electrocardio gating period reference value, so that the time for collecting the electrocardio gating signal is insufficient, and the electrocardio gating signal is discarded.
The device can screen out the collectable electrocardio gating signals in the respiratory stationary phase, and the collectable electrocardio gating signals are used as composite gating signals for triggering cardiac magnetic resonance imaging. The composite gating signals are obtained in the respiratory stationary phase, and the heart is in a diastolic state in the respiratory stationary phase, so that the acquired composite gating signals are used for triggering the magnetic resonance imaging of the heart, cardiac motion artifacts caused by respiratory activity can be reduced, and imaging quality is improved.
Optionally, the period reference value first obtaining module 301 specifically includes:
the first acquisition unit is used for acquiring the electrocardio gating signals corresponding to the N periods, acquiring N electrocardio gating periods, acquiring the longest electrocardio gating period from the N electrocardio gating periods, and taking the longest electrocardio gating period as the electrocardio gating period reference value; and N is a positive integer.
In this embodiment, the remaining acquisition time of each of the cardiac gating signals is then compared with the cardiac gating period reference value, and if the acquisition time is smaller than the cardiac gating period reference value, the cardiac gating signals are filtered out. In the implementation manner, the longest electrocardio gating period is obtained from the N electrocardio gating periods and is used as an electrocardio gating period reference value, namely, the electrocardio gating signals with insufficient residual acquisition time are screened out as far as possible, the failure of the retained electrocardio gating signals to trigger cardiac magnetic resonance imaging is avoided, and the success rate of cardiac data acquisition is improved.
Optionally, the period reference value first obtaining module 301 specifically includes:
the second acquisition unit is used for acquiring the electrocardio gating signals corresponding to the N periods, obtaining N electrocardio gating periods, removing the maximum value and the minimum value of the electrocardio gating periods from the N electrocardio gating periods, obtaining the average value of the rest N-2 electrocardio gating periods, and taking the average value of the N-2 electrocardio gating periods as the electrocardio gating period reference value; and N is a positive integer greater than 2.
In this implementation, the maximum value and the minimum value of the cardiac gating period are removed from the N cardiac gating periods, that is, the maximum value and the minimum value are regarded as abnormal values which are not representative, and the maximum value and the minimum value are not considered. The average value of the N-2 electrocardio gating periods is used as an electrocardio gating period reference value by calculating the average value of the remaining N-2 electrocardio gating periods, so that the electrocardio gating period reference value has stronger applicability in later use and has practical reference value.
Optionally, the period reference value second obtaining module 302 specifically includes:
the third acquisition unit is used for acquiring respiratory gating signals corresponding to N periods, obtaining N respiratory gating periods, obtaining the shortest respiratory gating period from the N respiratory gating periods, and taking the shortest respiratory gating period as the respiratory gating period reference value; and N is a positive integer.
In this embodiment, the remaining acquisition time of each cardiac gating signal in the respiratory stationary phase is calculated according to the respiratory gating period reference value, the remaining acquisition time is compared with the cardiac gating period reference value, and if the remaining acquisition time is greater than or equal to the cardiac gating period reference value, the cardiac gating signal is screened to be used as a composite gating signal. In the implementation manner, the shortest respiratory gating period is obtained from the N respiratory gating periods and used as a respiratory gating period reference value, namely, the residual acquisition time of the screened electrocardio gating signals is ensured to be relatively sufficient as far as possible, the failure of triggering cardiac magnetic resonance imaging by the reserved electrocardio gating signals is avoided, and the success rate of cardiac data acquisition is improved.
Optionally, the period reference value second obtaining module 302 specifically includes:
a fourth obtaining unit, configured to collect respiratory gating signals corresponding to N periods, obtain N respiratory gating periods, reject a maximum value and a minimum value of the respiratory gating periods from the N respiratory gating periods, obtain an average value of the remaining N-2 respiratory gating periods, and use the average value of the N-2 respiratory gating periods as the respiratory gating period reference value; and N is a positive integer greater than 2.
In this implementation, the maximum value and the minimum value of the breath gating period are removed from the N breath gating periods, that is, the maximum value and the minimum value are taken as abnormal values which are not representative, and the maximum value and the minimum value are not considered. The average value of the N-2 respiration gating periods is used as the respiration gating period reference value by calculating the average value of the remaining N-2 respiration gating periods, so that the respiration gating period reference value has stronger applicability in later use and has practical reference value.
Optionally, the apparatus may further include:
and the initial time determining module is used for obtaining the initial time of the respiratory stability period of the respiratory gating signal by utilizing the rising edge and the gating delay time of the respiratory gating signal.
After the initial moment of the respiratory stationary phase is determined through the module, the screening of the electrocardio gating signals with the residual acquisition time meeting the requirements from the moment is facilitated.
It should be noted that, the device for acquiring the composite gate control signal provided by the embodiment of the application can implement the functions of each module and unit by means of hardware devices such as a singlechip, a complex programmable logic device (Complex Programmable Logic Device, CPLD) or a field programmable gate array (Field Programmable Gate Array, FPGA).
Based on the device, the application further provides magnetic resonance equipment. Specific implementations of the apparatus are described below with reference to the accompanying drawings.
Referring to fig. 4, a schematic structural diagram of a magnetic resonance apparatus according to an embodiment of the present application is shown.
As shown in fig. 4, the magnetic resonance apparatus provided by the present application includes: acquisition means 401 of the composite gating signal, and a controller 402.
The acquiring device 401 of the composite gate signal is the acquiring device described above.
The input end of the composite gating signal acquisition device 401 is a respiratory gating signal and an electrocardiographic gating signal, and the output end is a composite gating signal. The apparatus 401 transmits the screening retained electrocardiographic gating signal to a controller of the magnetic resonance device.
The controller 402 is configured to receive an electrocardiographic gating signal sent by the acquiring device 401, and control the magnetic resonance device to perform magnetic resonance imaging according to the electrocardiographic gating signal.
The composite gating signals are obtained in the respiratory phase, and because the heart is in a diastolic state in the respiratory phase and the heart motion is relatively static, the controller 402 of the magnetic resonance equipment triggers the magnetic resonance imaging of the heart according to the composite gating signals acquired by the acquisition device 401 of the composite gating signals, so that the heart motion artifact caused by respiratory activity can be reduced, and the imaging quality is improved.
Some existing systems can acquire an electrocardiographic gating signal or acquire a respiratory gating signal independently, and then perform magnetic resonance scanning imaging operation on the heart according to triggering of the electrocardiographic gating signal or the respiratory gating signal. The method and the device for acquiring the composite gate control signal provided by the embodiment of the application can be realized by means of the existing hardware, and avoid modifying the existing hardware structure. Compared with the prior gating signal acquisition devices in some systems, the composite gating signal acquisition device provided by the embodiment of the application can acquire and selectively transmit different gating signals. A magnetic resonance apparatus comprising the acquisition means for the composite gating signal is described in detail below with reference to fig. 5.
Referring to fig. 5, a functional schematic of a magnetic resonance apparatus according to an embodiment of the present application is shown.
As shown in fig. 5, the magnetic resonance apparatus includes: an acquisition device 401 of the composite gate control signal and a controller 402. The composite gating signal acquiring device 401 is specifically capable of implementing the function of the pre-learning gating judger 4011 and the function of the gating selector 4012.
In this embodiment, the function of the pre-learning gating determiner 4011 refers to all the functions of the apparatus for acquiring the composite gating signal in the foregoing apparatus embodiment.
The gating selector 4012 can select one of the respiratory gating signal, the electrocardiographic gating signal and the composite gating signal according to the working requirement of the magnetic resonance device, and send the gating signal to the controller 402 of the magnetic resonance device, so that the controller 402 performs a control operation corresponding to the working requirement under the triggering of the received gating signal.
As can be seen from fig. 5, the magnetic resonance apparatus is capable of performing magnetic resonance imaging from a respiratory gating signal, an electrocardiographic gating signal or a composite gating signal according to different operational requirements. When performing magnetic resonance imaging on the heart, in order to reduce cardiac motion artifacts in the image, magnetic resonance scanning can be performed specifically according to the composite gating signal, thereby improving the cardiac magnetic resonance imaging quality.
In order to implement the method and the device for acquiring the composite gating signal provided by the embodiment of the application, in practical application, the algorithm in the existing hardware can be only modified, and the existing equipment which can only independently complete the triggering of the electrocardio gating signal or the respiratory gating signal can be upgraded into the comprehensive magnetic resonance equipment which can support the triggering of the electrocardio gating signal, the respiratory gating signal or the composite gating signal by modifying the algorithm.
Therefore, compared with the prior art, the method and the device for acquiring the composite gating signal and the magnetic resonance equipment provided by the embodiment have no too high requirements on hardware and a system, and are easy to realize. The magnetic resonance equipment (system) is upgraded in function, and has no influence on sequences, interfaces, software and the like. In addition, the magnetic resonance equipment does not need excessive parameter setting participated by equipment users, improves user experience, and meets various working requirements.
The above description is only of the preferred embodiment of the present application, and is not intended to limit the present application in any way. While the application has been described with reference to preferred embodiments, it is not intended to be limiting. Any person skilled in the art can make many possible variations and modifications to the technical solution of the present application or modifications to equivalent embodiments using the methods and technical contents disclosed above, without departing from the scope of the technical solution of the present application. Therefore, any simple modification, equivalent variation and modification of the above embodiments according to the technical substance of the present application still fall within the scope of the technical solution of the present application.

Claims (13)

1. The method for acquiring the composite gating signal is characterized by comprising the following steps of:
obtaining an electrocardio gating period reference value by using an electrocardio gating signal, and obtaining a respiration gating period reference value by using a respiration gating signal;
in the period of each respiratory gating signal, starting timing from the initial moment of the respiratory stationary phase of the respiratory gating signal, and obtaining the falling edge moment of each electrocardiograph gating signal;
obtaining a first difference value between the respiratory gating period reference value and the respiratory gating delay time;
judging whether the difference between the first difference value and the falling edge moment of the electrocardio gating signal is larger than or equal to the electrocardio gating period reference value or not;
if yes, the electrocardio gating signal is sent to a controller of magnetic resonance equipment; and if not, discarding the electrocardio gating signal.
2. The method according to claim 1, wherein the obtaining the reference value of the cardiac gating period by using the cardiac gating signal specifically comprises:
acquiring electrocardio gating signals corresponding to N periods, obtaining N electrocardio gating periods, obtaining the longest electrocardio gating period from the N electrocardio gating periods, and taking the longest electrocardio gating period as the electrocardio gating period reference value; and N is a positive integer.
3. The method according to claim 1, wherein the obtaining the reference value of the cardiac gating period by using the cardiac gating signal specifically comprises:
collecting electrocardio gating signals corresponding to N periods to obtain N electrocardio gating periods, removing the maximum value and the minimum value of the electrocardio gating periods from the N electrocardio gating periods to obtain the average value of the rest N-2 electrocardio gating periods, and taking the average value of the N-2 electrocardio gating periods as the electrocardio gating period reference value; and N is a positive integer greater than 2.
4. The method according to claim 1, wherein the obtaining a respiratory gating period reference value using a respiratory gating signal, in particular comprises:
collecting respiratory gating signals corresponding to N periods, obtaining N respiratory gating periods, obtaining a shortest respiratory gating period from the N respiratory gating periods, and taking the shortest respiratory gating period as a respiratory gating period reference value; and N is a positive integer.
5. The method according to claim 1, wherein the obtaining a respiratory gating period reference value using a respiratory gating signal, in particular comprises:
collecting respiratory gating signals corresponding to N periods to obtain N respiratory gating periods, removing the maximum value and the minimum value of the respiratory gating periods from the N respiratory gating periods to obtain the average value of the remaining N-2 respiratory gating periods, and taking the average value of the N-2 respiratory gating periods as the respiratory gating period reference value; and N is a positive integer greater than 2.
6. The acquisition method according to any one of claims 1 to 5, characterized by further comprising: and obtaining the initial moment of the respiratory stability period of the respiratory gating signal by using the rising edge of the respiratory gating signal and the respiratory gating delay time.
7. An apparatus for acquiring a composite gating signal, comprising:
the first acquisition module is used for acquiring an electrocardio gating period reference value by utilizing an electrocardio gating signal;
the second acquisition module is used for acquiring a respiratory gating period reference value by utilizing the respiratory gating signal;
the falling edge time acquisition module is used for starting timing from the initial time of the respiratory stability period of the respiratory gating signal in the period of each respiratory gating signal to acquire the falling edge time of each electrocardiograph gating signal;
the first difference value acquisition module is used for acquiring a first difference value between the respiratory gating period reference value and the respiratory gating delay time;
the judging module is used for judging whether the difference between the first difference value and the falling edge moment of the electrocardio gating signal is larger than or equal to the electrocardio gating period reference value or not;
if yes, the signal sending module is used for sending the electrocardio gating signal to a controller of the magnetic resonance equipment; and if not, the signal discarding module is used for discarding the electrocardio gating signal.
8. The acquisition device according to claim 7, wherein the period reference value first acquisition module specifically includes:
the first acquisition unit is used for acquiring the electrocardio gating signals corresponding to the N periods, acquiring N electrocardio gating periods, acquiring the longest electrocardio gating period from the N electrocardio gating periods, and taking the longest electrocardio gating period as the electrocardio gating period reference value; and N is a positive integer.
9. The acquisition device according to claim 7, wherein the period reference value first acquisition module specifically includes:
the second acquisition unit is used for acquiring the electrocardio gating signals corresponding to the N periods, obtaining N electrocardio gating periods, removing the maximum value and the minimum value of the electrocardio gating periods from the N electrocardio gating periods, obtaining the average value of the rest N-2 electrocardio gating periods, and taking the average value of the N-2 electrocardio gating periods as the electrocardio gating period reference value; and N is a positive integer greater than 2.
10. The acquisition device according to claim 7, wherein the period reference value second acquisition module specifically includes:
the third acquisition unit is used for acquiring respiratory gating signals corresponding to N periods, obtaining N respiratory gating periods, obtaining the shortest respiratory gating period from the N respiratory gating periods, and taking the shortest respiratory gating period as the respiratory gating period reference value; and N is a positive integer.
11. The acquisition device according to claim 7, wherein the period reference value second acquisition module specifically includes:
a fourth obtaining unit, configured to collect respiratory gating signals corresponding to N periods, obtain N respiratory gating periods, reject a maximum value and a minimum value of the respiratory gating periods from the N respiratory gating periods, obtain an average value of the remaining N-2 respiratory gating periods, and use the average value of the N-2 respiratory gating periods as the respiratory gating period reference value; and N is a positive integer greater than 2.
12. The acquisition device of any one of claims 7-11, further comprising:
and the initial time determining module is used for obtaining the initial time of the respiratory stability period of the respiratory gating signal by utilizing the rising edge of the respiratory gating signal and the respiratory gating delay time.
13. A magnetic resonance apparatus, comprising: a controller, and the acquisition device of any one of claims 7-12;
the controller is used for receiving the electrocardio gating signals sent by the acquisition device and controlling the magnetic resonance equipment to perform magnetic resonance imaging according to the electrocardio gating signals.
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