CN110031283A - A kind of biological gene detection sample low temperature storage device - Google Patents

A kind of biological gene detection sample low temperature storage device Download PDF

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Publication number
CN110031283A
CN110031283A CN201910381171.6A CN201910381171A CN110031283A CN 110031283 A CN110031283 A CN 110031283A CN 201910381171 A CN201910381171 A CN 201910381171A CN 110031283 A CN110031283 A CN 110031283A
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CN
China
Prior art keywords
sample
spring
sliding rail
coupon
sleeve
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Withdrawn
Application number
CN201910381171.6A
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Chinese (zh)
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魏绘
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Individual
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Individual
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Priority to CN201910381171.6A priority Critical patent/CN110031283A/en
Publication of CN110031283A publication Critical patent/CN110031283A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/42Low-temperature sample treatment, e.g. cryofixation

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a kind of biological gene detection sample low temperature storage devices, including refrigeration cabinets, sample box and coupon, the both ends of the refrigeration cabinets bottom end are mounted on universal wheel, the air compressor output end is equipped with the refrigerator pipes through refrigeration cabinets, the refrigerator pipes run through sample box top far from one end of air compressor, lower horizontal inside the sample box is equipped with third sliding rail, the middle position on second sliding block top is vertically-mounted hydraulic cylinder, second sliding block top all homogeneous verticals of the hydraulic cylinder two sides are equipped with sleeve, the second spring top is vertically-mounted the metallic rod through sleeve top, sleeve top on the outside of the metallic rod is vertically-mounted the first spring being connected with coupon, bottom end homogeneous vertical inside the sample storehouse is equipped with the 4th spring.Biological gene detection sample low temperature storage device, when the temperature is excessively high, air compressor starting refrigeration is convenient for cryo-conservation sample.

Description

A kind of biological gene detection sample low temperature storage device
Technical field
The present invention relates to biological gene detection technique field, specially a kind of biological gene detection is filled with sample cryo-conservation It sets.
Background technique
Gene is that the basic unit of heredity carries the DNA or RNA sequence of hereditary information, and hereditary information is passed by replicating The next generation is passed, instructs the synthesis of protein to express the hereditary information entrained by oneself, to control the character of bion Expression, it is to take detected person periphery quiet that genetic test, which is the technology detected by blood, other body fluid or cell to DNA, Arteries and veins blood or other histocytes, after expanding its gene information, by particular device to the DNA molecular information in detected person's cell It detects, gene type contained by it and gene defect and its a kind of whether normal method of expressive function is analyzed, to make People will appreciate that the gene information of oneself, specifies the cause of disease or predicts the risk that body suffers from certain disease, biological gene detects pilot scale Sample needs low temperature storage device to be saved.
But most of biological gene detections currently on the market are not easy to detection and control device with sample low temperature storage device Internal temperature, and biological gene detection is not applied for various sizes of Storage of sample with sample low temperature storage device and fills It sets.
Summary of the invention
The purpose of the present invention is to provide a kind of biological gene detection sample low temperature storage devices, to solve above-mentioned background The problem of being proposed in technology.
To achieve the above object, the invention provides the following technical scheme: a kind of biological gene detection sample cryo-conservation Device, including refrigeration cabinets, sample box and coupon, the both ends of the refrigeration cabinets bottom end are mounted on universal wheel, and make The middle position of cold box house bottom end is equipped with air compressor, and the air compressor output end is equipped with through refrigeration The refrigerator pipes of cabinet, and the top of refrigeration cabinets is equipped with sample box, the refrigerator pipes are passed through far from one end of air compressor Sample box top is worn, the lower horizontal inside the sample box is equipped with third sliding rail, and is equipped with inside third sliding rail The second sliding block to match with third sliding rail, the middle position on second sliding block top is vertically-mounted hydraulic cylinder, and liquid The output end of cylinder pressure is vertically-mounted hydraulic stem, and the second sliding block top all homogeneous verticals of the hydraulic cylinder two sides are equipped with set Cylinder, and the inner vertical of sleeve is equipped with second spring, the second spring top is vertically-mounted the gold through sleeve top Belong to bar, and the top of metallic rod and hydraulic stem is equipped with coupon, the sleeve top on the outside of the metallic rod is vertically-mounted have with The first spring that coupon is connected, and the inside of coupon is evenly arranged with sample storehouse, the bottom end inside the sample storehouse is equal It is even it is vertically-mounted have the 4th spring, and the top of the 4th spring is horizontally installed with bearing sheet, the sample storehouse of the bearing sheet two sides Inner wall is vertically-mounted the 4th sliding rail, and is equipped with the Four-slider to match with the 4th sliding rail inside the 4th sliding rail, described Four-slider is connected with bearing sheet, and the top of sample storehouse inside circumference is mounted on third spring, and third spring is remote One end from sample storehouse is equipped with fixed ring, and the inner wall of the fixed ring is pasted with rubber spacer, third sliding rail two sides Sample box inner wall is vertically-mounted the first sliding rail, and is equipped with first to match with the first sliding rail inside the first sliding rail and slides Block, first sliding block are equipped with the second sliding rail far from the side of the first sliding rail, and are equipped with inside the second sliding rail and coupon The third sliding block being connected, one end of the sample box inner tip are equipped with single-chip microcontroller, and the sample case of single-chip microcontroller side Body inner tip is equipped with temperature sensor, and the positive two sides of sample box pass through articulated shaft and are hinged with door body, described The output end of temperature sensor is electrically connected by the input terminal of conducting wire and single-chip microcontroller, and the output end of single-chip microcontroller by conducting wire with The input terminal of air compressor is electrically connected.
Preferably, the universal wheel is provided with two groups, and universal wheel is internally provided with arrestment mechanism.
Preferably, the metallic rod is by constituting telescoping mechanism between second spring and sleeve, and sleeve passes through the first bullet Telescoping mechanism is constituted between spring and coupon, and metallic rod, sleeve, second spring and the first spring are provided with two groups, together When every group of metallic rod, sleeve, second spring and the first spring about the central axes of coupon be symmetrical arranged.
Preferably, the coupon is by constituting sliding equipment between third sliding block and the second sliding rail, and the second sliding rail is logical It crosses between the first sliding block and the first sliding rail and constitutes sliding equipment.
Preferably, the rubber spacer and fixed ring, which pass through, constitutes telescoping mechanism between third spring and sample storehouse, and Sample storehouse is set in qually spaced in inside coupon.
Preferably, the door body is by constituting rotating mechanism between articulated shaft and sample box.
Compared with prior art, the beneficial effects of the present invention are: biological gene detection sample low temperature storage device, leads to Cross door body, coupon, the second sliding block, third sliding block, third sliding rail and the second sliding rail of installation, the pulling when needing to store sample Handle drives door body to rotate by articulated shaft, and pulling coupon passes through the second sliding block and third sliding block in third sliding rail and the respectively It is skidded off inside two sliding rails, when needing to take out sample, principle is identical, consequently facilitating quick fetching sample, passes through the sample case of installation Body, temperature sensor, single-chip microcontroller, air compressor and refrigerator pipes, inside sample box when the temperature is excessively high, temperature sensor It detected in time and signal passed into single-chip microcontroller, cold air warp of the single-chip microcontroller control air compressor starting to freeze Refrigerator pipes are blown into inside sample box, consequently facilitating cryo-conservation sample, by the sample storehouse of installation, bearing sheet, the 4th spring, Third spring, fixed ring and rubber spacer, when needing to store the sample storing unit of different-diameter, by sample storing unit according to It is secondary to be put into inside sample storehouse, drive bearing sheet to squeeze the 4th spring under the effect of gravity, the band under the elastic force effect of third spring Dynamic fixed ring and rubber spacer squeeze the surrounding of fixed sample storing unit, consequently facilitating the sample of storage different-diameter stores dress It sets, by the hydraulic cylinder of installation, hydraulic stem, coupon, the second sliding rail, the first sliding block and the first sliding rail, when needs store height When biggish sample storing unit, starting hydraulic cylinder drives hydraulic stem flexible, and hydraulic stem drives coupon and the second sliding rail to pass through First sliding block slide downward inside the first sliding rail, consequently facilitating the biggish sample storing unit of storage height.
Detailed description of the invention
Fig. 1 is that the present invention faces schematic cross-sectional view;
Fig. 2 is positive structure diagram of the present invention;
Fig. 3 is that present invention back regards structural schematic diagram;
Fig. 4 is that fixed ring of the present invention, sample storehouse, third spring with rubber spacer connect overlooking structure diagram;
Fig. 5 is the portion A enlarged structure schematic diagram in Fig. 1 of the present invention.
In figure: 1, the first sliding rail;2, the first sliding block;3, the second sliding rail;4, the first spring;5, refrigeration cabinets;6, the second bullet Spring;7, universal wheel;8, hydraulic stem;9, air compressor;10, hydraulic cylinder;11, sleeve;12, third sliding rail;13, the second sliding block; 14, metallic rod;15, third sliding block;16, sample box;17, temperature sensor;18, fixed ring;19, sample storehouse;20, third bullet Spring;21, single-chip microcontroller;22, door body;23, refrigerator pipes;24, rubber spacer;25, the 4th sliding rail;26, Four-slider;27, coupon; 28, the 4th spring;29, bearing sheet.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Fig. 1-5 is please referred to, a kind of embodiment provided by the invention: a kind of biological gene detection sample cryo-conservation dress It sets, including refrigeration cabinets 5, sample box 16 and coupon 27, the both ends of 5 bottom end of refrigeration cabinets are mounted on universal wheel 7, universal Wheel 7 is provided with two groups, and universal wheel 7 is internally provided with arrestment mechanism, easy to remove, and the centre of 5 inner bottom of refrigeration cabinets Air compressor 9 is installed, the model of the air compressor 9 can be VW-3/7 air compressor, air compressor 9 at position Output end is equipped with the refrigerator pipes 23 through refrigeration cabinets 5, and the top of refrigeration cabinets 5 is equipped with sample box 16, refrigerator pipes 16 top of sample box is run through in 23 one end far from air compressor 9, and the lower horizontal inside sample box 16 is equipped with third Sliding rail 12, and the second sliding block 13 to match with third sliding rail 12 is installed inside third sliding rail 12,13 top of the second sliding block Middle position is vertically-mounted hydraulic cylinder 10, and the model of the hydraulic cylinder 10 can be J64RT2UNIVER telescopic cylinder, and liquid The output end of cylinder pressure 10 is vertically-mounted hydraulic stem 8, and 13 top of the second sliding block all homogeneous verticals of 10 two sides of hydraulic cylinder are equipped with Sleeve 11, and the inner vertical of sleeve 11 is equipped with second spring 6,6 top of second spring is vertically-mounted to be had through the top of sleeve 11 The metallic rod 14 at end, metallic rod 14 is by constituting telescoping mechanism between second spring 6 and sleeve 11, and sleeve 11 passes through the first bullet Telescoping mechanism is constituted between spring 4 and coupon 27, and metallic rod 14, sleeve 11, second spring 6 and the first spring 4 are respectively provided with There are two groups, while the central axes of every group of metallic rod 14, sleeve 11, second spring 6 and the first spring 4 about coupon 27 are symmetrical Setting, convenient for stablizing, and the top of metallic rod 14 and hydraulic stem 8 is equipped with coupon 27, and coupon 27 passes through third sliding block 15 And second constitute sliding equipment between sliding rail 3, and the second sliding rail 3 is by constituting skate machine between the first sliding block 2 and the first sliding rail 1 Structure, convenient for picking and placing sample, 11 top of sleeve in 14 outside of metallic rod is vertically-mounted the first spring being connected with coupon 27 4, and the inside of coupon 27 is evenly arranged with sample storehouse 19, the bottom end homogeneous vertical inside sample storehouse 19 is equipped with the 4th spring 28, and the top of the 4th spring 28 is horizontally installed with bearing sheet 29,19 inner wall of sample storehouse of 29 two sides of bearing sheet is vertically-mounted There is the 4th sliding rail 25, and the Four-slider 26 to match with the 4th sliding rail 25, Four-slider 26 are installed inside the 4th sliding rail 25 It is connected with bearing sheet 29, the top of 19 inside circumference of sample storehouse is mounted on third spring 20, and third spring 20 is far from examination The one end in sample storehouse 19 is equipped with fixed ring 18, and the inner wall of fixed ring 18 is pasted with rubber spacer 24, rubber spacer 24 and fixed ring 18 by constituting telescoping mechanism between third spring 20 and sample storehouse 19, and sample storehouse 19 is set in qually spaced in coupon 27 Portion, convenient for the sample storing unit of fixed different-diameter, 16 inner wall of sample box of 12 two sides of third sliding rail is vertically-mounted to be had First sliding rail 1, and the first sliding block 2 to match with the first sliding rail 1 is installed inside the first sliding rail 1, the first sliding block 2 is far from first The side of sliding rail 1 is equipped with the second sliding rail 3, and the third sliding block 15 being connected with coupon 27 is equipped with inside the second sliding rail 3, One end of 16 inner tip of sample box is equipped with single-chip microcontroller 21, and 16 inner tip of the sample box installation of 21 side of single-chip microcontroller There is temperature sensor 17, the positive two sides of sample box 16 pass through articulated shaft and are hinged with door body 22, and door body 22 passes through articulated shaft Rotating mechanism is constituted between sample box 16, convenient for picking and placing sample, the output end of temperature sensor 17 passes through conducting wire and monolithic The input terminal of machine 21 is electrically connected, and the output end of single-chip microcontroller 21 is electrically connected by the input terminal of conducting wire and air compressor 9.
Working principle: when using biological gene detection sample low temperature storage device, universal wheel 7 is first passed through by the life Object genetic test is moved to the appropriate position with sample low temperature storage device, and when needing to store sample, pull handle drives door body 22 It is rotated by articulated shaft, pulls coupon 27 sliding in third sliding rail 12 and second by the second sliding block 13 and third sliding block 15 respectively It is skidded off inside rail 3, when needing to take out sample, principle is identical, consequently facilitating quick fetching sample, inside sample box 16 When the temperature is excessively high, temperature sensor 17 detected in time and signal passed to single-chip microcontroller 21, and single-chip microcontroller 21 controls air pressure The starting of contracting machine 9 is to blow into inside sample box 16 cold air of refrigeration through refrigerator pipes 23, consequently facilitating cryo-conservation sample, When needing to store the sample storing unit of different-diameter, sample storing unit is sequentially placed into inside sample storehouse 19, in gravity Effect is lower to drive bearing sheet 29 to squeeze the 4th spring 28, drives fixed ring 18 and rubber pad under the elastic force effect of third spring 20 Layer 24 squeezes the surrounding of fixed sample storing units, consequently facilitating the sample storing unit of storage different-diameter, when needing to store Highly biggish sample storing unit when, starting hydraulic cylinder 10 drives hydraulic stem 8 flexible, and hydraulic stem 8 drives coupon 27 and the Two sliding rails 3, in 1 inside slide downward of the first sliding rail, are filled by the first sliding block 2 consequently facilitating storing the biggish sample storage of height It sets.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims Variation is included within the present invention.Any reference signs in the claims should not be construed as limiting the involved claims.

Claims (6)

1. a kind of biological gene detection sample low temperature storage device, including refrigeration cabinets (5), sample box (16) and coupon (27), it is characterised in that: the both ends of refrigeration cabinets (5) bottom end are mounted on universal wheel (7), and refrigeration cabinets (5) are internal The middle position of bottom end is equipped with air compressor (9), and air compressor (9) output end is equipped with through refrigeration cabinets (5) refrigerator pipes (23), and the top of refrigeration cabinets (5) is equipped with sample box (16), the refrigerator pipes (23) are far from air Sample box (16) top is run through in one end of compressor (9), and the internal lower horizontal of the sample box (16) is equipped with third Sliding rail (12), and the second sliding block (13) to match with third sliding rail (12) is installed inside third sliding rail (12), described second The middle position on sliding block (13) top is vertically-mounted to be had hydraulic cylinder (10), and the output end of hydraulic cylinder (10) vertically-mounted has liquid The second sliding block (13) top all homogeneous verticals of compression bar (8), hydraulic cylinder (10) two sides are equipped with sleeve (11), and sleeve (11) inner vertical is equipped with second spring (6), and second spring (6) top is vertically-mounted to be had through sleeve (11) top Metallic rod (14), and the top of metallic rod (14) and hydraulic stem (8) is equipped with coupon (27), on the outside of the metallic rod (14) Sleeve (11) top it is vertically-mounted have the first spring (4) being connected with coupon (27), and the inside of coupon (27) is equal Even to be provided with sample storehouse (19), the internal bottom end homogeneous vertical of the sample storehouse (19) is equipped with the 4th spring (28), and the 4th The top of spring (28) is horizontally installed with bearing sheet (29), and sample storehouse (19) inner wall of bearing sheet (29) two sides is pacified vertically The Four-slider (26) to match with the 4th sliding rail (25) is installed equipped with the 4th sliding rail (25), and inside the 4th sliding rail (25), The Four-slider (26) is connected with bearing sheet (29), and the top of sample storehouse (19) inside circumference is mounted on third bullet Spring (20), and third spring (20) is equipped with fixed ring (18) far from the one end of sample storehouse (19), the fixed ring (18) it is interior Wall is pasted with rubber spacer (24), and sample box (16) inner wall of third sliding rail (12) two sides is vertically-mounted to have first to slide Rail (1), and the first sliding block (2) to match with the first sliding rail (1), first sliding block (2) are installed inside the first sliding rail (1) Side far from the first sliding rail (1) is equipped with the second sliding rail (3), and is equipped with and coupon (27) phase inside the second sliding rail (3) One end of the third sliding block (15) of connection, sample box (16) inner tip is equipped with single-chip microcontroller (21), and single-chip microcontroller (21) sample box (16) inner tip of side is equipped with temperature sensor (17), the positive two sides of the sample box (16) It is hinged with door body (22) by articulated shaft, the output end of the temperature sensor (17) is defeated by conducting wire and single-chip microcontroller (21) Enter end to be electrically connected, and the output end of single-chip microcontroller (21) is electrically connected by conducting wire and the input terminal of air compressor (9).
2. a kind of biological gene detection sample low temperature storage device according to claim 1, it is characterised in that: described ten thousand Wheel (7) is provided with two groups, and universal wheel (7) is internally provided with arrestment mechanism.
3. a kind of biological gene detection sample low temperature storage device according to claim 1, it is characterised in that: the gold Belong to bar (14) by constituting telescoping mechanism between second spring (6) and sleeve (11), and sleeve (11) pass through the first spring (4) and Telescoping mechanism is constituted between coupon (27), and metallic rod (14), sleeve (11), second spring (6) and the first spring (4) are equal Two groups are provided with, while every group of metallic rod (14), sleeve (11), second spring (6) and the first spring (4) are about coupon (27) central axes are symmetrical arranged.
4. a kind of biological gene detection sample low temperature storage device according to claim 1, it is characterised in that: the examination Sample block (27) is by constituting sliding equipment between third sliding block (15) and the second sliding rail (3), and the second sliding rail (3) is sliding by first Sliding equipment is constituted between block (2) and the first sliding rail (1).
5. a kind of biological gene detection sample low temperature storage device according to claim 1, it is characterised in that: the rubber Rubber mat layer (24) and fixed ring (18) are by constituting telescoping mechanism, and sample storehouse between third spring (20) and sample storehouse (19) (19) it is internal to be set in qually spaced in coupon (27).
6. a kind of biological gene detection sample low temperature storage device according to claim 1, it is characterised in that: the door Body (22) is by constituting rotating mechanism between articulated shaft and sample box (16).
CN201910381171.6A 2019-05-08 2019-05-08 A kind of biological gene detection sample low temperature storage device Withdrawn CN110031283A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910381171.6A CN110031283A (en) 2019-05-08 2019-05-08 A kind of biological gene detection sample low temperature storage device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910381171.6A CN110031283A (en) 2019-05-08 2019-05-08 A kind of biological gene detection sample low temperature storage device

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CN110031283A true CN110031283A (en) 2019-07-19

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111361849A (en) * 2020-03-26 2020-07-03 黑龙江省农业科学院水稻研究所 Sample storage device for field investigation and sampling
CN111999151A (en) * 2020-08-25 2020-11-27 华南农业大学 Glass slide dyeing device and using method thereof
CN112849765A (en) * 2021-01-07 2021-05-28 镇江波菲尔生物科技有限公司 Sample induction and storage device for biomedicine

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111361849A (en) * 2020-03-26 2020-07-03 黑龙江省农业科学院水稻研究所 Sample storage device for field investigation and sampling
CN111999151A (en) * 2020-08-25 2020-11-27 华南农业大学 Glass slide dyeing device and using method thereof
CN111999151B (en) * 2020-08-25 2024-08-23 华南农业大学 Slide glass dyeing device and application method thereof
CN112849765A (en) * 2021-01-07 2021-05-28 镇江波菲尔生物科技有限公司 Sample induction and storage device for biomedicine

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Application publication date: 20190719