CN110025872A - A kind of sacculus dilating catheter of the lower developability of enhancing ultrasound - Google Patents

A kind of sacculus dilating catheter of the lower developability of enhancing ultrasound Download PDF

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Publication number
CN110025872A
CN110025872A CN201810029787.2A CN201810029787A CN110025872A CN 110025872 A CN110025872 A CN 110025872A CN 201810029787 A CN201810029787 A CN 201810029787A CN 110025872 A CN110025872 A CN 110025872A
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CN
China
Prior art keywords
sacculus
developing
dilating catheter
distance
sacculus dilating
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CN201810029787.2A
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Chinese (zh)
Inventor
王铮
孟娟
袁振华
范渊杰
宋健
冯勇
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Medtronic Inc
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Medtronic Inc
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Application filed by Medtronic Inc filed Critical Medtronic Inc
Priority to CN201810029787.2A priority Critical patent/CN110025872A/en
Publication of CN110025872A publication Critical patent/CN110025872A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/104Balloon catheters used for angioplasty

Abstract

The invention discloses a kind of sacculus dilating catheters of the lower developability of enhancing ultrasound, the sacculus dilating catheter includes catheter body and the developing parts in catheter body, the developing parts protrude from the catheter body catheter body in the radial direction, in radial directions, the distance between outer surface of the highest point of the developing parts and catheter body H is more than or equal to 0.5 times of ultrasonic wavelength.Visibility is high under ultrasound guidance for sacculus dilating catheter of the present invention, developability is good, overcome in the prior art sacculus dilating catheter developability poor problem when using ultrasonic guidance, thus, in balloon expandable operation described in sacculus dilating catheter be more easily positioned.

Description

A kind of sacculus dilating catheter of the lower developability of enhancing ultrasound
Technical field
The present invention relates to a kind of medical instrument more particularly to a kind of sacculus dilating catheters.
Background technique
Vascular access is the life of Maintained on hemodialysis (maintenance hemodialysis, hereinafter referred to as MHD) patient Line is ordered, and prevents and treat related complication, for maintaining vascular function unobstructed most important.Wherein, vascular access complications In self or artificial internal arteriovenous fistula is narrow, occlusion is most commonly seen.
Currently, the processing means narrow for self or artificial internal arteriovenous fistula include surgical operation and interventional therapy, Middle interventional therapy can be repeated, and can retain the blood vessel resource of hemodialysis patients to the maximum extent because easy, minimally invasive, In recent years by favor.Interventional therapy refers to percutaneous transluminal angioplasty (Percutaneous Transluminal Angioplasty, hereinafter referred to as PTA) balloon dilatation, it is to be expanded narrow blood vessel using sacculus dilating catheter, from And restore vascular access.When carrying out PTA balloon expandable, can be operated in X-ray or ultrasound guidance, but due to X-ray Guidance exist need special installation place, required contrast medium make patient face in allergy and renal damage risk, therapeutic process patient with And medical staff has the limitation for being exposed to the harm of X-ray radiation, and therefore, in the narrow treatment of internal arteriovenous fistula, More tendency uses ultrasonic guidance.However, using ultrasonic guidance, there are sacculus dilating catheter developability is poor in the prior art Problem.
It is rare under ultrasound primarily directed to the improvement of developability under X-ray in the past in technology improved for developability The analysis and research and improvement of developability, and developer, developing parts are concentrated on for the improved technology scheme of developability under X-ray Density etc., it is not fully identical to improve principle with the developability under ultrasound.
Based on this, it is expected that obtaining a kind of sacculus dilating catheter, the sacculus dilating catheter developability is good, it is seen that property is high, especially It is to be easy to position sacculus dilating catheter when using the interventional therapy of ultrasonic guidance.
Summary of the invention
The purpose of the present invention is to provide a kind of sacculus dilating catheter of the lower developability of enhancing ultrasound, the sacculus dilating catheters Visibility is high under ultrasound guidance, and developability is good, overcomes and is developed in the prior art using sacculus dilating catheter when ultrasonic guidance Property poor problem, thus, in balloon expandable operation, the sacculus dilating catheter is more easily positioned.
Based on above-mentioned purpose, the invention proposes a kind of sacculus dilating catheter of the lower developability of enhancing ultrasound, the sacculus Dilating catheter includes catheter body and the developing parts in catheter body, and the developing parts are in the radial direction side of catheter body It projects upwards in the catheter body, and in radial directions, the highest point of the developing parts and the outer surface of catheter body The distance between H be more than or equal to 0.5 times of ultrasonic wavelength.
In the prior art, it is made for the developing parts major part of development of metal platinum iridium alloy material, developing parts Thickness it is generally lower, the ultrasonic wavelength less than 0.5 times, therefore developability is poor under its ultrasound.And if increasing this gold Belong to the thickness of developing parts, and the service performances such as tracing property and passability that will affect product.
For the technical program, it is intended to improve the developability under ultrasound.And according to inventor the study found that ultrasound Under developability it is not only related with the density of developing parts, and from optical principles such as the absorption of ultrasonic wave, reflections, Also and the size of developing parts, shape and its related with the relationship of ultrasonic wavelength.Based on above-mentioned influence factor, from ultrasonic development Property factor set out, inventor carries out size design and structure to developing parts and designs, to propose the technical program, It is developability to significantly improve the sacculus dilating catheter under ultrasound.
For ultrasonography, the resolving power of ultrasound image is the weight for evaluating image space resolving power and clarity Want parameter.The resolving power of usual ultrasound image is concerned with spatial resolution, when spatial resolution refers to ultrasonic examination, display screen On can distinguish the abilities of two thin objects, the i.e. minimum range of the two targets.Spatial resolution can divide according to direction difference Are as follows: azimuthal resolution, lateral resolution and transverse resolution.Wherein, azimuthal resolution is also referred to as vertical definition, refers in sound The ability of two targets is distinguished on the beam direction of propagation, the frequency of it and ultrasonic wave has certain relationship.Azimuthal resolution it is excellent The bad fineness that will affect target on shallow deep direction.If the resolving power of ultrasonography is good, it is characterized as on axial direction Picture point it is tiny, clearly.When azimuthal resolution is greater than λ/2 (wherein λ indicate ultrasonic wavelength), can be identified by ultrasonic wave. The axial direction of above-mentioned ultrasonic wave corresponds to the radial direction of sacculus dilating catheter.
And in fact, propagation of the ultrasonic wave in tissue includes that interface is reflected, scattering, reflects, diffraction (is also referred to as spread out Penetrate) etc..The reflection of its median surface and refraction are the bases of ultrasound diagnosis, and very sensitive, the acoustic impedance between two media is reflected at interface As long as difference will generate apparent reflection 0.1%.Therefore, the echo institute generated is reflected according to interface and reflected to medical worker The information for bringing human body respectively to organize carries out ultrasonic diagnosis.When ultrasonic wave does not reflect, then it cannot get required information, but When ultrasonic reflections are too strong, then the ultrasonic energy entered in next medium is too weak, also cannot get required information.For human body For tissue, liquid tissue is areflexia type, and gassiness tissue is fully reflective.And substantially homogeneous solid tissue is few reflection Type, structure is complicated, fine and close, and solid tissue of the arrangement without certain regularity is multiple reflection type.
Therefore, for sacculus dilating catheter of the present invention, if catheter body outer surface is put down in the axial direction Straight and smooth or structure is single, then catheter body can be made to be few reflection-type tissue, so as to cause ultrasonic reflections compared with It is few, it is unfavorable for the position of ultrasonic wave identification developing parts, is based on this, sacculus dilating catheter of the present invention sets developing parts It is set to and protrudes from the catheter body in the radial direction in catheter body, so that catheter body outer surface is in the axial direction On it is not straight or rough.
In addition, inventor is had found by numerous studies and experiment: setting developing parts in radial directions, development section The distance between the outer surface of the highest point of part and catheter body H is more than or equal to 0.5 times of ultrasonic wavelength, can greatly improve The developability of developing parts.
Further, under enhancing ultrasound of the present invention in the sacculus dilating catheter of developability, the developing parts Highest point and catheter body ultrasonic wavelength of the distance between the outer surface H more than or equal to 0.5 times and less than or equal to 1 times Ultrasonic wavelength.
In the technical scheme, for sacculus dilating catheter, inventor has comprehensively considered development in the course of the research The thickness of component passes through lesion region to conduit into the influence of sheath force value and the thickness of developing parts to sacculus dilating catheter The influence of ability, it is thus preferable that the distance between the outer surface of the highest point of developing parts and catheter body H is designed are as follows: Ultrasonic wavelength more than or equal to 0.5 times and the ultrasonic wavelength less than or equal to 1 times.
Further, under enhancing ultrasound of the present invention in the sacculus dilating catheter of developability, the catheter body Including what is set gradually along its axial direction: tip, sacculus and outer tube, wherein being equipped with the axial direction along catheter body in the sacculus The inner tube that direction is arranged and is connected to the outer tube.
Further, under enhancing ultrasound of the present invention in the sacculus dilating catheter of developability, the developing parts It including at least a developing ring, is sheathed in said inner tube, the length of the developing ring is less than or equal to the isometrical of the sacculus The length of section, the distance H be between developing ring highest point in radial directions and the outer surface of said inner tube away from From.
In the technical scheme, if the length of developing ring and isometrical section of the sacculus of length are identical or essentially identical, It then can effectively show the effective length (i.e. the isometrical segment length of sacculus) of sacculus.Certainly, in other implementations, this is aobvious The length of shadow ring might be less that the isometrical segment length of sacculus, and in this case, which can be correspondingly arranged at sacculus etc. The middle part of diameter section, to show the position of sacculus.
Further, under enhancing ultrasound of the present invention in the sacculus dilating catheter of developability, the developing parts Including at least two developing rings, which is sheathed in said inner tube, which at least wraps Include two developing rings of isometrical section of two ends setting of the corresponding sacculus;The distance H is the developing ring in radial direction The distance between the outer surface of highest point and said inner tube on direction.
It is envisioned that the quantity of developing ring can be arranged according to specific requirements in the art in the technical scheme For two, three, four or more.Set developing ring includes at least the corresponding sacculus as a preferred technical solution, Isometrical section of two ends setting two developing rings, to show the effective length (i.e. the isometrical segment length of sacculus) of sacculus.
Further, under enhancing ultrasound of the present invention in the sacculus dilating catheter of developability, the developing parts Including at least two spirals development part, wherein each spiral development part is spirally wound along the axial direction of inner tube in inner tube On, two spirals that at least two spiral development part includes at least isometrical section of two ends setting of the corresponding sacculus are aobvious Shadow part;The distance H be the spiral develop between part highest point in radial directions and the outer surface of said inner tube away from From.
It is envisioned that the quantity of spiral development part can be according to specific requirements in the art in the technical scheme It is set as two, three, four or more.Set spiral development part, which includes at least, as a preferred technical solution, corresponds to Two spirals of isometrical section of two ends setting of the sacculus are developed part, to show effective length (the i.e. sacculus of sacculus Isometrical segment length).
In the technical scheme, inventor is when considering the resolving power of ultrasound image, other than considering azimuthal resolution, Also contemplate lateral resolution.The lateral resolution of ultrasonic wave refers in the vertical plane of beam axis, in probe long axis side To resolving power, determined by the beam width of acoustic beam scanning direction.The lateral axial direction for corresponding to foley's tube of ultrasonic wave.Hair Bright people's discovery can be designed by the structure of developing parts to improve lateral resolution, this spiral knot of spiral development part Structure makes it be rendered as a kind of structure of noncontinuity in the axial direction, i.e., has interval, this knot between adjacent entity Structure be conducive to increase developing parts it is lateral on discrimination and identification, so that it is super to increase sacculus dilating catheter of the present invention Developability under sound.
Further, under enhancing ultrasound of the present invention in the sacculus dilating catheter of developability, the developing parts Develop part including spiral, the spiral part that develops is spirally wound along the axial direction of inner tube in inner tube, which develops part Axial length is less than or equal to isometrical section of length of the sacculus;The distance H is that the spiral develops part in radial direction On highest point and the distance between the outer surface of said inner tube.The length of part and isometrical section of the sacculus if spiral is developed Length is identical or essentially identical, then can effectively show the effective length (i.e. the isometrical segment length of sacculus) of sacculus.Certainly, at it In his embodiment, the length of spiral development part might be less that the isometrical segment length of sacculus, in this case, the spiral shell Rotation development part can be correspondingly arranged at isometrical section of sacculus of middle part, to show the position of sacculus.
Further, under enhancing ultrasound of the present invention in the sacculus dilating catheter of developability, the developing parts Including vertebra shape development part, the axial length of vertebra shape development part is less than or equal to isometrical section of length of the sacculus;Institute Stating vertebra shape development part includes that spaced lug boss and concave part, the distance H are the protrusion in its axial direction The distance between portion's highest point in radial directions and the outer surface of said inner tube.
In this embodiment, inventor is also intended to further increase by the structure design of developing parts lateral Resolving power.Similarly, vertebra shape develops part due to being arranged at intervals with form different lug boss and groove in its axial direction Portion, so that a kind of its structure for being rendered as noncontinuity in the axial direction, this structure is conducive to increase developing parts Discrimination and identification on lateral, to increase the developability under sacculus dilating catheter ultrasound of the present invention.If vertebra Shape develop part length it is identical or essentially identical with isometrical section of the sacculus of length, then can effectively show the effective of sacculus Length (i.e. the isometrical segment length of sacculus).Certainly, in other implementations, the length of vertebra shape development part can also be small In the isometrical segment length of sacculus, in this case, vertebra shape development part can be correspondingly arranged at isometrical section of sacculus of middle part, from And show the position of sacculus.
Further, the development is made in the sacculus dilating catheter of developability under enhancing ultrasound of the present invention Percent mass proportioning >=40% of metal and/or metallic compound in the material of component.
As described above, in the technical scheme, inventor is when considering the resolving power of ultrasound image, in addition to considering axis To except resolving power, it is also contemplated that lateral resolution.For technical solutions according to the invention, inventor, which is expected that by, to be made Developing parts from catheter body there is different density to improve lateral resolution.Since catheter body is generally by high molecular material Be made, thus inventor the material of developing parts is arranged with the mass percent of metal and/or metallic compound >= 40%, this density of material for allowing for developing parts is higher than the density of material of catheter body, and has specific close therebetween System, to increase the lateral resolution of developing parts, and then improves development effect.In the technical scheme, above-mentioned metal And/or metallic compound is used as developing material.
Further, the development is made in the sacculus dilating catheter of developability under enhancing ultrasound of the present invention The material of component includes the polymer containing developing material, and the polymer containing developing material includes: the polymer of tungstenic, bismuth-containing Polymer, baric polymer and polymer containing tantalum at least one.
It should be noted that in the present case, the polymer of bismuth-containing, the polymer of baric and polymer containing tantalum either Containing bismuth metal, barium metal, metal tantalum polymer, be also possible to the polymer or two of the metallic compound of baric, bismuth and tantalum The combination of person.For example, the polymer of the metallic compound of baric can be containing BaSO4Polymer, the metallic compound of bismuth-containing Polymer can be containing Bi2O3Polymer, the polymer of the metallic compound containing tantalum can be the polymer containing tantalum oxide. And for the polymer of tungstenic, it is preferable that the preferably polymer containing tungsten.
In above scheme, material used by developing parts not only allows for the developability of developing parts under ultrasound, and Have also contemplated the biocompatibility of material, the ability that sacculus dilating catheter passes through lesion into sheath force value and sacculus dilating catheter.
Further, described containing development under enhancing ultrasound of the present invention in the sacculus dilating catheter of developability The polymer of material includes at least the polymer of tungstenic.This is because: the lower developability of substance of ultrasound and the density positive of substance It closes, the bigger substance of density, the lower developability of ultrasound is better.Since the density of tungsten is higher, in the equivalent situation of tenor Under, the ultrasonic development of tungsten is preferable.Further, since the density of tungsten is higher, when with mixed with polymers, high developer is being filled The flexibility that polymer can also be taken into account while content, reaches the superiority of actual use.Based on this, of the present invention In technical solution, the material of the developing parts preferably uses the polymer of tungstenic.
Further, under enhancing ultrasound of the present invention in the sacculus dilating catheter of developability, the polymer choosing From it is following at least one: polyethylene, polypropylene, polyester, polyamide, polyetheramides, polyurethane, polysulfones, polycarbonate and At least one of polylactic acid.
Further, under enhancing ultrasound of the present invention in the sacculus dilating catheter of developability, the developing parts Including at least a developing ring, which is sheathed on isometrical section of the sacculus, the length of the developing ring and the sacculus Isometrical section of length it is identical or essentially identical, the distance H be the highest point of the developing ring in radial directions with it is described Isometrical section of the distance between outer surface of sacculus.
Further, under enhancing ultrasound of the present invention in the sacculus dilating catheter of developability, the developing parts Including at least two developing rings, which is sheathed on isometrical section of the sacculus, at least two development Ring includes at least two developing rings set on isometrical section of two ends of the sacculus;The distance H is that the developing ring exists Highest point and isometrical section of the sacculus of the distance between outer surface in the radial direction.
Further, under enhancing ultrasound of the present invention in the sacculus dilating catheter of developability, the developing parts Including at least the first developing ring and the second developing ring, wherein the first developing ring is sheathed on the outer tube close to sacculus, second is aobvious Shadow ring is sheathed on the tip close to sacculus, the distance H be the highest point of the first developing ring in radial directions with it is described The outer surface at the highest point of the distance between outer surface of outer tube and the second developing ring in radial directions and the tip it Between distance.
It should be noted that each technical characteristic further and further described herein, is not occurring In the case where conflicting or conflict, can mutually it be freely combined to form a variety of different technical solutions.
Visibility is high under ultrasound guidance for the sacculus dilating catheter of the lower developability of enhancing ultrasound of the present invention, developability It is good, sacculus dilating catheter developability poor problem when using ultrasonic guidance in the prior art is overcome, thus, in balloon expandable Sacculus dilating catheter of the present invention is more easily positioned when operation.
Detailed description of the invention
Fig. 1 shows the knot of the sacculus dilating catheter of the lower developability of enhancing ultrasound of the present invention in example 1 Structure.
Fig. 2 shows the knot of the catheter body in the sacculus dilating catheter of the lower developability of enhancing ultrasound of the present invention Structure.
Fig. 3 shows the structure of the developing parts in sacculus dilating catheter shown in FIG. 1 with being further amplified.
The part Fig. 4 shows the balloon expandable conduit of the lower developability of enhancing ultrasound of the present invention in example 2 Structure.
Fig. 5 shows the structure of the developing parts in sacculus dilating catheter shown in Fig. 4 with being further amplified.
The part Fig. 6 shows the balloon expandable conduit of the lower developability of enhancing ultrasound of the present invention in the third embodiment Structure.
Fig. 7 shows the structure of the developing parts in sacculus dilating catheter shown in fig. 6 with being further amplified.
The part Fig. 8 shows the balloon expandable conduit of the lower developability of enhancing ultrasound of the present invention in example IV Structure.
Fig. 9 shows the structure of the developing parts in sacculus dilating catheter shown in Fig. 8 with being further amplified.
The part Figure 10 shows the balloon expandable conduit of the lower developability of enhancing ultrasound of the present invention in embodiment five Structure.
The part Figure 11 shows the balloon expandable conduit of the lower developability of enhancing ultrasound of the present invention in embodiment six Structure.
Figure 12 shows that the sacculus dilating catheter of the lower developability of enhancing ultrasound of the present invention is aobvious in embodiment seven Shadow effect.
Figure 13 shows the development effect of sacculus dilating catheter as a comparison case.
Sacculus dilating catheter of the Figure 14 as the sacculus dilating catheter for comparatively showing embodiment seven and as a comparison case Development effect.
Figure 15 shows the sacculus dilating catheter of the lower developability of enhancing ultrasound of the present invention in example 1 aobvious Shadow effect.
Specific embodiment
Come below in conjunction with Figure of description and specific embodiment to the lower developability of enhancing ultrasound of the present invention Sacculus dilating catheter is further described in detail, but the detailed description is not construed as limiting the invention.
Embodiment one
Fig. 1 shows the knot of the sacculus dilating catheter of the lower developability of enhancing ultrasound of the present invention in example 1 Structure.
Fig. 2 shows the knot of the catheter body in the sacculus dilating catheter of the lower developability of enhancing ultrasound of the present invention Structure.
As depicted in figs. 1 and 2, in the present embodiment, the sacculus dilating catheter of the lower developability of enhancing ultrasound includes conduit sheet Body and the developing ring 41 in catheter body.Wherein, catheter body includes setting gradually along its axial direction: tip 5, ball Capsule 1 and outer tube 3 are wherein equipped with the inner tube 2 for being arranged and being connected to outer tube 3 along the axial direction of catheter body in sacculus 1.Two aobvious Shadow ring 41 is set in the inner tube 2 of catheter body, and it protrudes from inner tube 2 in radial directions.It can from Fig. 1 Out, the two developing rings 41 respectively correspond two ends setting of isometrical section of sacculus 1, for showing the effective of sacculus 1 Length (i.e. the isometrical segment length of sacculus 1).
Fig. 3 shows the structure of the developing parts in sacculus dilating catheter shown in FIG. 1 with being further amplified.
From figure 3, it can be seen that in the present embodiment, in radial directions, highest point (the i.e. developing ring of developing ring 41 41 outer surface) it with the distance between the outer surface of inner tube 2 is H, H is more than or equal to 0.5 times of ultrasonic wavelength, it is preferable that H is big In the ultrasonic wavelength equal to 0.5 times and the ultrasonic wavelength less than or equal to 1 times.
It should be noted that in some other embodiments, the quantity of developing ring 41 can be set according to actual needs It is set to three, four or more.
In addition, in the present embodiment, mass percent >=40% of metal component in the material of developing ring 41 is made, this makes The density of material for obtaining developing ring 41 is higher than the high molecular material density of inner tube 2, so that the lateral resolution of developing ring 41 is increased, And then improve development effect.
Certainly, those skilled in the art know, developing ring 41 can also use high molecular material, but its development is imitated Fruit will be inferior to the developing ring of above-mentioned mass percent >=40% using metal component.
Embodiment two
The part Fig. 4 shows the balloon expandable conduit of the lower developability of enhancing ultrasound of the present invention in example 2 Structure.
Fig. 5 shows the structure of the developing parts in sacculus dilating catheter shown in Fig. 4 with being further amplified.
In example 2, the structure in addition to developing parts of sacculus dilating catheter is the same as example 1, thus Details are not described herein.Emphasis describes the structure of developing parts in embodiment two herein.As shown in Figure 4 and Figure 5, and if necessary it ties Fig. 1 is closed, in the present embodiment, developing parts include two spirals development parts 42, and wherein each spiral develops part 42 along interior The axial direction of pipe 2 is spirally wound in inner tube 2, and two of isometrical section of the corresponding sacculus 1 of the two spirals development part 42 End setting, for showing the effective length of sacculus 1.This sped structure of spiral development part 42 makes it in axial direction Be rendered as a kind of noncontinuity structure on direction, this noncontinuity structure be conducive to increase developing parts it is lateral on discrimination And identification, to increase the developability under sacculus dilating catheter ultrasound.
In addition, as more preferably technical solution, be made spiral development part 42 material can be set to metal and/or Mass percent >=40% of metallic compound, this makes the density of material of spiral development part 42 higher than the macromolecule material of inner tube 2 Expect density, to further increase the lateral resolution of spiral development part 42, and then further improves development effect.
From figure 5 it can be seen that in the present embodiment, in radial directions, highest point (the i.e. spiral shell of spiral development part 42 The outer surface of rotation development part 42) it with the distance between the outer surface of inner tube 2 is H, H is more than or equal to 0.5 times of ultrasonic wavelength, excellent Selection of land, ultrasonic wavelength of the H more than or equal to 0.5 times and the ultrasonic wavelength less than or equal to 1 times.
It should be noted that in some other embodiments, the quantity of spiral development part 42 can be according to practical need It is set as three, four or more.
Embodiment three
The part Fig. 6 shows the balloon expandable conduit of the lower developability of enhancing ultrasound of the present invention in the third embodiment Structure.
Fig. 7 shows the structure of the developing parts in sacculus dilating catheter shown in fig. 6 with being further amplified.
In the third embodiment, the structure and embodiment one and embodiment two-phase in addition to developing parts of sacculus dilating catheter Together, thus details are not described herein.Emphasis describes the structure of developing parts in embodiment three herein.As shown in Figure 6 and Figure 7, and Fig. 1 is combined when necessary, and in the present embodiment, developing parts include vertebra shape development part 43, and the axial direction of vertebra shape development part 43 is long Degree be substantially equal to or close to sacculus 1 isometrical section of length, for show sacculus 1 effective length.The development of vertebra shape Part 43 includes spaced lug boss 431 and concave part 432 in its axial direction.The vertebra shape develops part 43 due at it Lug boss 431 and concave part 432 are arranged at intervals on axial direction, so that it is rendered as a kind of non-company in the axial direction The structure of continuous property, this structure be conducive to increase developing parts it is lateral on discrimination and identification, to increase balloon expandable Developability under catheter-based ultrasound.
In addition, as more preferably technical solution, the material that vertebra shape development part 43 is made in the present embodiment can be with It is set as mass percent >=40% of metal and/or metallic compound, this makes the density of material of vertebra shape development part 43 high In the high molecular material density of inner tube 2, to further increase the lateral resolution of vertebra shape development part 43, Jin Erjin One step improves development effect.
It can be seen from figure 7 that in the present embodiment, in radial directions, the highest point of vertebra shape development part 43 is (i.e. Vertebra shape develop part 43 lug boss 431 outer surface) with the distance between the outer surface of inner tube 2 be H, H is more than or equal to 0.5 times Ultrasonic wavelength, it is preferable that ultrasonic wavelength of the H more than or equal to 0.5 times and be less than or equal to 1 times of ultrasonic wavelength.
Example IV
The part Fig. 8 shows the balloon expandable conduit of the lower developability of enhancing ultrasound of the present invention in example IV Structure.
Fig. 9 shows the structure of the developing parts in sacculus dilating catheter shown in Fig. 8 with being further amplified.
In example IV, the structure in addition to developing parts and embodiment one of sacculus dilating catheter, embodiment two and Embodiment three is identical, thus details are not described herein.Emphasis describes the structure of developing parts in example IV herein.Such as Fig. 8 and Fig. 9 It is shown, and Fig. 1 is combined if necessary, in the present embodiment, developing parts include spiral development part 44, spiral development 44 edge of part The axial direction of inner tube 2 is spirally wound in inner tube 2, and axial length is substantially equal to or close to isometrical section of sacculus 1 Length, for showing the effective length of sacculus 1.This sped structure of spiral development part 44 makes it in the axial direction On be rendered as a kind of noncontinuity structure, this noncontinuity structure be conducive to increase developing parts it is lateral on discrimination and distinguish Knowledge and magnanimity, to increase the developability under sacculus dilating catheter ultrasound.
In addition, as more preferably technical solution, metal in the material that spiral development part 44 is made in the present embodiment And/or mass percent >=40% of metallic compound, this makes the density of material of spiral development part 44 higher than the high score of inner tube 2 Sub- density of material to further increase the lateral resolution of spiral development part 44, and then further improves development Effect.
It can be seen in figure 9 that in the present embodiment, in radial directions, highest point (the i.e. spiral shell of spiral development part 44 The outer surface of rotation development part 44) it with the distance between the outer surface of inner tube 2 is H, H is more than or equal to 0.5 times of ultrasonic wavelength, excellent Selection of land, ultrasonic wavelength of the H more than or equal to 0.5 times and the ultrasonic wavelength less than or equal to 1 times.
Embodiment five
Figure 10 shows knot of the balloon expandable conduit of the lower developability of enhancing ultrasound of the present invention in embodiment five Structure.
In embodiment five, the structure in addition to developing parts of sacculus dilating catheter with it is above-mentioned respectively implement it is identical, because And details are not described herein.Emphasis describes the structure of developing parts in embodiment five herein.As shown in Figure 10, in the present embodiment, Two developing rings 41 are no longer arranged in inner tube 2 as shown in embodiment one, but are sheathed on isometrical section of sacculus 1, two Developing ring 41 is respectively arranged on two ends of isometrical section of sacculus 1, to show the effective length of sacculus 1.
In the present embodiment, in radial directions, the highest point (i.e. the outer surface of developing ring 41) and ball of developing ring 41 The distance between isometrical section outer surface of capsule 1 is H, and H is more than or equal to 0.5 times of ultrasonic wavelength, it is preferable that H is more than or equal to 0.5 times of ultrasonic wavelength and it is less than or equal to 1 times of ultrasonic wavelength.
In the present embodiment, be sheathed on due to developing ring 41 on the outer surface of sacculus 1, in view of biocompatibility and Sacculus dilating catheter easily enters object tissue, and the material of developing ring 41 is preferably the polymer containing developing material.
It is envisioned that in some other embodiments, the quantity of developing ring 41 can be set according to actual needs It is set to three, four or more.
Embodiment six
Figure 11 shows knot of the balloon expandable conduit of the lower developability of enhancing ultrasound of the present invention in embodiment six Structure.
Developing parts in the present embodiment are also used such as the developing ring 41 in embodiment one and embodiment five, with embodiment One and embodiment five unlike, as shown in figure 11, one in two developing rings 41 in the present embodiment is arranged close to sacculus 1 In on outer tube 3, another is then sheathed on tip 5 close to sacculus 1.Unlike aforementioned several embodiments, it is arranged in this way The total length of sacculus 1 is shown in two developing rings 41, that is, includes the total length of isometrical section and conical section.
In the present embodiment, in radial directions, the highest point (i.e. the outer surface of developing ring 41) of developing ring 41 and outer The distance between pipe 3 and tip 5 are H, and H is more than or equal to 0.5 times of ultrasonic wavelength, it is preferable that H is more than or equal to 0.5 times Ultrasonic wavelength and it is less than or equal to 1 times of ultrasonic wavelength.
In the present embodiment, it is sheathed on due to developing ring 41 on the outer surface at outer tube 3 and tip 5, in view of biology Compatibility and sacculus dilating catheter easily enter object tissue, and the material of developing ring 41 is preferably the polymer containing developing material.
Embodiment seven
In embodiment seven, the structure in addition to developing parts and embodiment one of sacculus dilating catheter, embodiment two and Embodiment three is identical, thus details are not described herein.Emphasis describes the structure of developing parts in embodiment seven herein.In the present embodiment In, developing parts include a developing ring, which is sheathed in inner tube 2, in the structure and embodiment one of the developing ring Developing ring 41 has no too big difference, and only the axial length of the developing ring will be considerably longer than the developing ring 41 in embodiment one, In the present embodiment, the axial length of the developing ring and isometrical section of sacculus 1 of length are identical or essentially identical, for display The effective length of sacculus 1.Certainly, in other implementations, the length of the developing ring might be less that isometrical section of sacculus Length, in this case, the developing ring can be correspondingly arranged at isometrical section of sacculus of middle part, thus the position of real sacculus.
In addition, the material that developing ring is made in the present embodiment can be set to gold as more preferably technical solution Mass percent >=40% of category and/or metallic compound, this makes the density of material of developing ring higher than the macromolecule material of inner tube 2 Expect density, to increase the lateral resolution of developing ring, and then further improves development effect.
Figure 12 shows development effect of the sacculus dilating catheter of embodiment seven under ultrasonic development.It can from Figure 12 Out, in the present embodiment, in radial directions, the outer surface of developing ring I is apparently higher than the outer surface highest point of inner tube.At this In embodiment, the distance between outer surface and the outer surface of inner tube 2 of developing ring I are more than or equal to 0.5 times of ultrasonic wavelength, excellent Selection of land, ultrasonic wavelength of the distance more than or equal to 0.5 times and the ultrasonic wavelength less than or equal to 1 times.
Design parameter used by the sacculus dilating catheter in each embodiment of this case is listed in table 1.
Table 1.
Distance H (mm) Ultrasonic wavelength λ (mm) 0.5λ(mm) Material used by developing parts
Embodiment one 0.050 0.0855 0.04275 The polyetheramides of tungstenic 40%
Embodiment two 0.064 0.128 0.064 Containing 40%BaSO4Polyurethane
Embodiment three 0.060 0.118 0.059 Containing 60%Bi2O3Polyester
Example IV 0.080 0.0855 0.04275 Polyamide containing tantalum 50%
Embodiment five 0.043 0.0855 0.04275 The polyetheramides of tungstenic 90%
Embodiment six 0.043 0.0855 0.04275 The polyamide of tungstenic 80%
Embodiment seven 0.050 0.0855 0.04275 The polyetheramides of tungstenic 90%
Comparative example 0.030 0.0855 0.04275 The polyetheramides of tungstenic 90%
As can be seen from Table 1, the highest point of developing parts in each embodiment and between the outer surface of catheter body Distance H is all larger than the ultrasonic wavelength equal to 0.5 times, so that sacculus dilating catheter is visible under ultrasound guidance in each embodiment Property it is high, developability is good, overcomes in the prior art using sacculus dilating catheter developability poor problem when ultrasonic guidance.
In order to further confirm the development effect of this case, Figure 12 to Figure 15 respectively illustrates embodiment one, embodiment seven Sacculus dilating catheter and development effect of the sacculus dilating catheter under ultrasonic development as a comparison case.Wherein:
Figure 12 shows that the sacculus dilating catheter of the lower developability of enhancing ultrasound of the present invention is aobvious in embodiment seven Shadow effect.
Figure 13 shows the development effect of sacculus dilating catheter as a comparison case.
Figure 14 shows the development effect of the sacculus dilating catheter and sacculus dilating catheter as a comparison case of embodiment seven.
Figure 15 shows the sacculus dilating catheter of the lower developability of enhancing ultrasound of the present invention in example 1 aobvious Shadow effect.
As seen from Figure 12, developing ring (position shown in I in figure) development effect of embodiment of this case seven is obvious, developing ring It is high-visible under ultrasound;And the developing ring (position shown in II in figure) of the sacculus dilating catheter in comparative example shown in Figure 13 is aobvious Shadow is bad.In addition, by comparative diagram Figure 14 it can also be seen that seven developing ring of embodiment of this case is apparently higher than pair at a distance from inner tube The developing ring of ratio is at a distance from inner tube.
It can be seen that in conjunction with table 1 and Figure 12 to Figure 14 since the developing ring distance H of embodiment of this case is more than or equal to 0.5 Ultrasonic wavelength again, thus it is consistent in ultrasonic wavelength, and in the identical situation of material used by developing parts, this case The development effect of embodiment seven is significantly better than comparative example.
In addition, as shown in figure 15, the sacculus dilating catheter of embodiment one is provided with two developing rings (position shown in III in figure Set), the arrangement architecture of two developing rings can dramatically increase the lateral resolution of ultrasonic development, thus, the ball in the present embodiment Capsule dilating catheter development effect is extremely high-visible.
Certainly, in order to further increase the development effect of sacculus dilating catheter, developing parts can also be set to two Above developing ring;Or spiral development part or vertebra shape development part are set by developing parts, to further increase ultrasound The lateral resolution of development, to further enhance the development effect of sacculus dilating catheter.
It should be noted that prior art part is not limited to given by present specification in protection scope of the present invention Embodiment, all prior arts not contradicted with the solution of the present invention, including but not limited to first patent document, formerly Public publication, formerly openly use etc., it can all be included in protection scope of the present invention.
In addition, in this case in the combination of each technical characteristic and unlimited this case claim documented combination or It is combination documented by specific embodiment, all technical characteristics that this case is recorded can be freely combined in any way Or combine, unless generating contradiction between each other.
It should be noted that the above list is only specific embodiments of the present invention, it is clear that the present invention is not limited to above real Example is applied, there are many similar variations therewith.If those skilled in the art directly exported from present disclosure or All deformations associated, are within the scope of protection of the invention.

Claims (15)

1. a kind of sacculus dilating catheter of the lower developability of enhancing ultrasound, the sacculus dilating catheter includes catheter body and set on leading Developing parts on tube body, it is characterised in that:
The developing parts protrude from the catheter body catheter body in the radial direction, and in radial directions, described The distance between the outer surface of the highest points of developing parts and catheter body H is more than or equal to 0.5 times of ultrasonic wavelength.
2. the sacculus dilating catheter of the lower developability of enhancing ultrasound as described in claim 1, which is characterized in that the developing parts Highest point and catheter body ultrasonic wavelength of the distance between the outer surface H more than or equal to 0.5 times and less than or equal to 1 times Ultrasonic wavelength.
3. the sacculus dilating catheter of the lower developability of enhancing ultrasound as claimed in claim 1 or 2, which is characterized in that the conduit Ontology includes setting gradually along its axial direction: tip, sacculus and outer tube, wherein being equipped in the sacculus along catheter body The inner tube that axial direction is arranged and is connected to the outer tube.
4. the sacculus dilating catheter of the lower developability of enhancing ultrasound as claimed in claim 3, which is characterized in that the developing parts It including at least a developing ring, is sheathed in said inner tube, the length of the developing ring is less than or equal to the isometrical of the sacculus The length of section, the distance H be between developing ring highest point in radial directions and the outer surface of said inner tube away from From.
5. the sacculus dilating catheter of the lower developability of enhancing ultrasound as claimed in claim 3, which is characterized in that the developing parts Including at least two developing rings, which is sheathed in said inner tube, which at least wraps Include two developing rings of isometrical section of two ends setting of the corresponding sacculus;The distance H is the developing ring in radial direction The distance between the outer surface of highest point and said inner tube on direction.
6. the sacculus dilating catheter of the lower developability of enhancing ultrasound as claimed in claim 3, which is characterized in that the developing parts Including at least two spirals development part, wherein each spiral development part is spirally wound along the axial direction of inner tube in inner tube On, two spirals that at least two spiral development part includes at least isometrical section of two ends setting of the corresponding sacculus are aobvious Shadow part;The distance H be the spiral develop between part highest point in radial directions and the outer surface of said inner tube away from From.
7. the sacculus dilating catheter of the lower developability of enhancing ultrasound as claimed in claim 3, which is characterized in that the developing parts Develop part including spiral, the spiral part that develops is spirally wound along the axial direction of inner tube in inner tube, which develops part Axial length is less than or equal to isometrical section of length of the sacculus;The distance H is that the spiral develops part in radial direction On highest point and the distance between the outer surface of said inner tube.
8. the sacculus dilating catheter of the lower developability of enhancing ultrasound as claimed in claim 3, which is characterized in that the developing parts Including vertebra shape development part, the axial length of vertebra shape development part is less than or equal to isometrical section of length of the sacculus;Institute Stating vertebra shape development part includes that spaced lug boss and concave part, the distance H are the protrusion in its axial direction The distance between portion's highest point in radial directions and the outer surface of said inner tube.
9. the sacculus dilating catheter of the lower developability of enhancing ultrasound as described in claim 1, which is characterized in that the development is made Percent mass proportioning >=40% of metal and/or metallic compound in the material of component.
10. the sacculus dilating catheter of the lower developability of enhancing ultrasound as described in claim 1, which is characterized in that be made described aobvious The material of shadow component includes the polymer containing developing material, and the polymer containing developing material includes: the polymer of tungstenic, contains At least one of the polymer of bismuth, the polymer of baric and the polymer containing tantalum.
11. the sacculus dilating catheter of the lower developability of enhancing ultrasound as claimed in claim 10, which is characterized in that described containing development The polymer of material includes at least the polymer of tungstenic.
12. the sacculus dilating catheter of the lower developability of enhancing ultrasound as claimed in claim 10, which is characterized in that the polymer Selected from it is following at least one: polyethylene, polypropylene, polyester, polyamide, polyetheramides, polyurethane, polysulfones, polycarbonate With polylactic acid at least one.
13. the sacculus dilating catheter of the lower developability of enhancing ultrasound as claimed in claim 3, which is characterized in that the development section Part includes at least a developing ring, which is sheathed on isometrical section of the sacculus, and the length of the developing ring is less than or waits In isometrical section of length of the sacculus, the distance H is the highest point of the developing ring in radial directions and the sacculus Isometrical section of the distance between outer surface.
14. the sacculus dilating catheter of the lower developability of enhancing ultrasound as claimed in claim 3, which is characterized in that the development section Part includes at least two developing rings set on isometrical section of two ends of the sacculus;The distance H is that the developing ring exists Isometrical section of the distance between outer surface of highest point and the sacculus in the radial direction.
15. the sacculus dilating catheter of the lower developability of enhancing ultrasound as claimed in claim 3, which is characterized in that the development section Part includes at least the first developing ring and the second developing ring, wherein the first developing ring is sheathed on the outer tube close to sacculus, second Developing ring is sheathed on the tip close to sacculus, and the distance H is the first developing ring highest point in radial directions and institute State the outer surface of the distance between outer surface of outer tube and the second developing ring highest point in radial directions and the tip The distance between.
CN201810029787.2A 2018-01-12 2018-01-12 A kind of sacculus dilating catheter of the lower developability of enhancing ultrasound Pending CN110025872A (en)

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CN115957425A (en) * 2022-12-29 2023-04-14 鼎科医疗技术(苏州)有限公司 Developable balloon dilatation catheter with folding-resistant conveying system

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Application publication date: 20190719