CN110021357A - 模拟癌症基因组测序数据生成装置 - Google Patents
模拟癌症基因组测序数据生成装置 Download PDFInfo
- Publication number
- CN110021357A CN110021357A CN201810256018.6A CN201810256018A CN110021357A CN 110021357 A CN110021357 A CN 110021357A CN 201810256018 A CN201810256018 A CN 201810256018A CN 110021357 A CN110021357 A CN 110021357A
- Authority
- CN
- China
- Prior art keywords
- variation
- cancer gene
- gene group
- simulation
- sequencing data
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
Landscapes
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biotechnology (AREA)
- Evolutionary Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
Abstract
Description
Claims (5)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2017114416586 | 2017-12-27 | ||
CN201711441658 | 2017-12-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN110021357A true CN110021357A (zh) | 2019-07-16 |
CN110021357B CN110021357B (zh) | 2021-06-04 |
Family
ID=67188304
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810256018.6A Active CN110021357B (zh) | 2017-12-27 | 2018-03-27 | 模拟癌症基因组测序数据生成装置 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN110021357B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111627492A (zh) * | 2020-05-25 | 2020-09-04 | 中国人民解放军军事科学院军事医学研究院 | 癌症基因组Hi-C数据仿真方法、装置和电子设备 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103299188A (zh) * | 2010-09-15 | 2013-09-11 | 阿尔玛克诊断有限公司 | 用于癌症的分子诊断试验 |
CN106202991A (zh) * | 2016-06-30 | 2016-12-07 | 厦门艾德生物医药科技股份有限公司 | 一种基因组多重扩增测序产物中突变信息的检测方法 |
CN106778065A (zh) * | 2016-12-30 | 2017-05-31 | 同济大学 | 一种基于多元数据预测dna突变影响蛋白互作的预测方法 |
US20170152570A1 (en) * | 2014-01-27 | 2017-06-01 | Dna-Seq, Inc. | Methods and systems for determination of an effective therapeutic regimen and drug discovery |
-
2018
- 2018-03-27 CN CN201810256018.6A patent/CN110021357B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103299188A (zh) * | 2010-09-15 | 2013-09-11 | 阿尔玛克诊断有限公司 | 用于癌症的分子诊断试验 |
US20170152570A1 (en) * | 2014-01-27 | 2017-06-01 | Dna-Seq, Inc. | Methods and systems for determination of an effective therapeutic regimen and drug discovery |
CN106202991A (zh) * | 2016-06-30 | 2016-12-07 | 厦门艾德生物医药科技股份有限公司 | 一种基因组多重扩增测序产物中突变信息的检测方法 |
CN106778065A (zh) * | 2016-12-30 | 2017-05-31 | 同济大学 | 一种基于多元数据预测dna突变影响蛋白互作的预测方法 |
Non-Patent Citations (2)
Title |
---|
IGOR F. TSIGELNY等: "Molecular dynamics use in personalized cancer medicine: Example of MET Y501C mutation", 《2016 6TH INTERNATIONAL CONFERENCE ON SIMULATION AND MODELING METHODOLOGIES, TECHNOLOGIES AND APPLICATIONS (SIMULTECH)》 * |
秦颖等: "利用循环上皮细胞采集器捕获循环肿瘤细胞进行基因突变检测", 《医学理论与实践》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111627492A (zh) * | 2020-05-25 | 2020-09-04 | 中国人民解放军军事科学院军事医学研究院 | 癌症基因组Hi-C数据仿真方法、装置和电子设备 |
CN111627492B (zh) * | 2020-05-25 | 2023-04-28 | 中国人民解放军军事科学院军事医学研究院 | 癌症基因组Hi-C数据仿真方法、装置和电子设备 |
Also Published As
Publication number | Publication date |
---|---|
CN110021357B (zh) | 2021-06-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Olson et al. | Best practices for evaluating single nucleotide variant calling methods for microbial genomics | |
Saber et al. | Benchmarking bacterial genome-wide association study methods using simulated genomes and phenotypes | |
Alland et al. | Modeling bacterial evolution with comparative-genome-based marker systems: application to Mycobacterium tuberculosis evolution and pathogenesis | |
Stephens et al. | Simulating next-generation sequencing datasets from empirical mutation and sequencing models | |
CN110491441B (zh) | 一种模拟人群背景信息的基因测序数据仿真系统及方法 | |
Pritchard et al. | ARTIST: high-resolution genome-wide assessment of fitness using transposon-insertion sequencing | |
Treangen et al. | Next generation sequence assembly with AMOS | |
Iantorno et al. | Who watches the watchmen? An appraisal of benchmarks for multiple sequence alignment | |
Johnson et al. | A better sequence-read simulator program for metagenomics | |
CN108363902B (zh) | 一种致病遗传变异的精确预测方法 | |
Lucas Lledó et al. | On the power and the systematic biases of the detection of chromosomal inversions by paired-end genome sequencing | |
Duncavage et al. | In silico proficiency testing for clinical next-generation sequencing | |
Patuzzi et al. | metaSPARSim: a 16S rRNA gene sequencing count data simulator | |
Zhou et al. | Estimating time to the most recent common ancestor (TMRCA): comparison and application of eight methods | |
Zackay et al. | MethVisual-visualization and exploratory statistical analysis of DNA methylation profiles from bisulfite sequencing | |
CN110021357A (zh) | 模拟癌症基因组测序数据生成装置 | |
CN107967411B (zh) | 一种脱靶位点的检测方法、装置及终端设备 | |
KR102004177B1 (ko) | 질병 유전자 발병 확률 보정 방법 및 그 장치 | |
Hellmuth et al. | The Theory of Gene Family Histories | |
Luhmann et al. | Comparative scaffolding and gap filling of ancient bacterial genomes applied to two ancient Yersinia pestis genomes | |
Wu et al. | InvBFM: finding genomic inversions from high-throughput sequence data based on feature mining | |
WO2014119914A1 (ko) | 유전자 서열 기반 개인 마커에 관한 정보를 제공하는 방법 및 이를 이용한 장치 | |
CN109920485B (zh) | 对测序序列进行变异模拟的方法及其应用 | |
Chu et al. | Simulating genetically heterozygous genomes in the tumour tissue according to its clonal evolution history | |
Krieger | A protocol for the creation of useful geometric shape metrics illustrated with a newly derived geometric measure of leaf circularity |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20210419 Address after: 322000 1st Floor, 9th Building, Standard Factory Building, No. 10 Gaoxin Road, Fujiang Street, Yiwu City, Jinhua City, Zhejiang Province Applicant after: ZHEJIANG ANNOROAD BIOTECHNOLOGY Co.,Ltd. Applicant after: Anouta gene technology (Beijing) Co.,Ltd. Address before: 100176 Beijing City, Daxing District branch of Beijing economic and Technological Development Zone Street 88 Hospital No. 8 Building 2 unit 701 room Applicant before: Anouta gene technology (Beijing) Co.,Ltd. |
|
GR01 | Patent grant | ||
GR01 | Patent grant |