CN110010227A - A kind of method, apparatus and system generating picture - Google Patents

A kind of method, apparatus and system generating picture Download PDF

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Publication number
CN110010227A
CN110010227A CN201910153492.0A CN201910153492A CN110010227A CN 110010227 A CN110010227 A CN 110010227A CN 201910153492 A CN201910153492 A CN 201910153492A CN 110010227 A CN110010227 A CN 110010227A
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Prior art keywords
pathological section
picture
scanner
pixel
cut
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CN201910153492.0A
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CN110010227B (en
Inventor
谢文龙
吕亚亚
李云鹏
沈军
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Visionvera Information Technology Co Ltd
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Visionvera Information Technology Co Ltd
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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00ICT specially adapted for the handling or processing of medical images
    • G16H30/40ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing

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  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Primary Health Care (AREA)
  • Public Health (AREA)
  • Image Processing (AREA)

Abstract

The present invention provides a kind of method method, apparatus and system for generating picture.The method is applied to medical field, the medical field includes: pathological section scanner, the described method includes: pathological section scanner receives pathological section, pathological section is cut according to presetted pixel, judge whether the pathological section pixel being cut into is less than presetted pixel, less than presetted pixel, then create a blank picture, the pathological section for being less than presetted pixel will be cut into and subsidize blank sheet on piece, save the blank picture after subsidizing, if being equal to presetted pixel, then directly save the pathological section being cut into, blank picture after subsidizing and the pathological section equal to presetted pixel being cut into are parsed and spliced, it is scanned again, generate pathological section entirety picture.According to the pathological section entirety picture is complete, clear of generation, edge zone will not be stretched the present invention, will not metamorphopsic distortion, improve medical personnel located to the diagnosis correctness of sufferer illness.

Description

A kind of method, apparatus and system generating picture
Technical field
The present invention relates to medical field more particularly to a kind of method, apparatus and system for generating picture.
Background technique
Pathological section is the widely applied medical procedure of medical field, takes a certain size pathological tissues, uses pathological tissue Method is made pathological section and (usually pathological tissues is embedded in paraffin mass, are thinly sliced with slicer, then with hematoxylin- Yihong (H-E) dyeing), the occurrence and development process of lesion is further checked with microscope, finally makes pathological diagnosis.It is pathology One kind of sample, processing when production by the tissue or internal organs that partially have lesion Jing Guo various chemicals and burying storage are allowed to solid Fixed hardening, thinly slices on slicer, is adhered on slide, contaminates with various colors, for checking under the microscope, to observe disease Reason variation, makes pathological diagnosis, provides help for clinical diagnosis and treatment.
Existing pathological section is all that observation under the microscope obtains as a result, generally picture format, but the picture is clear Clear degree is poor, and medical professional needs to check that this picture is taken other medical institutions by the picture or sufferer, asks other doctors When treating staff's inspection state of an illness, mistaken diagnosis may be generated, consequence is than more serious.
Pathological section scanner is that digitlization pathological section scanner replaces traditional microscope with high precision, realizes tradition The digital information of pathological section, the picture clarity for generating pathological section is very high, but pathological section scanner generates picture Same cutting technique is used with the picture that traditional microscope generates, it is simple in order to cut, 256*256 is pressed in integral part Pixel cuts and parses splicing, when cutting to marginal portion, marginal dimension it is long or it is wide 256 length in pixels have been not achieved, but cut Cutting off is still to be saved by 256*256 pixel, and such picture will necessarily be stretched deformation, causes to be distorted, although this part Distortion is not very big for overall image, it might even be possible to be ignored, but when lesion locations are just at this position, it is possible to lead Cause mistaken diagnosis.
Summary of the invention
The method, apparatus and system of a kind of method generating picture provided by the invention, solve and generate picture use Cutting technique, at edge when deficiency presetted pixel, still according to presetted pixel cut so that picture is stretched, cause to deform The problem of distortion.
In order to solve the above-mentioned technical problem, the embodiment of the invention provides a kind of method the method applications for generating picture In medical field, the medical field includes: pathological section scanner, and the pathological section scanner is by pathological section number Information-based smart machine, which comprises
The pathological section scanner receives pathological section;
The pathological section scanner cuts the pathological section according to presetted pixel;
Whether the pathological section pixel that the pathological section scanner judgement is cut into is less than the presetted pixel;
If the pathological section pixel being cut into is less than the presetted pixel, the pathological section scanner creation one The pixel of a blank picture, the blank picture is equal to the presetted pixel;
The pathological section scanner subsidizes the blank sheet for the pathological section for being less than the presetted pixel is cut into On piece;
The pathological section scanner saves the blank picture after subsidizing;
If the pathological section pixel being cut into is equal to the presetted pixel, the pathological section scanner is directly protected Deposit the pathological section being cut into;
The pathological section scanner is to the blank picture after described subsidize and what is be cut into be equal to the presetted pixel Pathological section is parsed and is spliced;
The pathological section scanner is scanned parsing and spliced pathological section, generates pathological section overall diagram Piece.
Optionally, the pathological section that the pathological section scanner will be cut into less than the presetted pixel subsidizes described Blank sheet on piece, comprising:
The pathological section scanner scans the blank picture;
The pathological section scanner subsidizes the blank picture for the pathological section for being less than presetted pixel is cut into The upper left corner.
Optionally, the pathological section scanner cuts the pathological section according to presetted pixel, comprising:
The pathological section scanner is successively cut according to sequence from left to right, from top to bottom with 256*256 pixel It cuts.
Optionally, the pathological section scanner is equal to the presetted pixel with what is be cut into the blank picture after subsidizing Pathological section, parsed and spliced, comprising:
If it is described subsidize after blank picture number there was only one, the pathological section scanner is directly subsidized described Blank picture afterwards is spliced with the pathological section equal to the presetted pixel being cut into;
If it is described subsidize after blank picture number be greater than one, after subsidizing described in pathological section scanner parsing Blank picture and the pathological section equal to the presetted pixel that is cut between positional relationship, then spliced.
Optionally, parsing and spliced pathological section are scanned in the pathological section scanner, generate pathology After being sliced whole picture, the method also includes:
If the pathological section entirety picture does not meet default picture, the pathological section scanner is to be higher than 256* 256 pixels are presetted pixel, repeat approach described above, regenerate pathological section entirety picture, the default picture is clear The clear picture for completely showing pathology;
If the pathological section entirety picture metamorphopsic distortion, the pathological section scanner repeats approach described above, Regenerate pathological section entirety picture.
The embodiment of the invention also provides a kind of device for generating picture, described device is applied to medical field, the doctor Treatment field includes: pathological section scanner, the pathological section scanner be by the smart machine of pathological section digital information, Described device includes:
Receiving module receives pathological section for the pathological section scanner;
Cutting module cuts the pathological section according to presetted pixel for the pathological section scanner;
It is described pre- to judge whether the pathological section pixel being cut into is less than for the pathological section scanner for judgment module If pixel;
Creation module, if the pathological section pixel for being cut into is less than the presetted pixel, the pathological section is swept It retouches instrument and creates a blank picture, the pixel of the blank picture is equal to the presetted pixel;
Scanning blank subsidizes module, will be cut into the pathology for being less than the presetted pixel for the pathological section scanner Slice subsidizes the blank sheet on piece;
Preserving module saves the blank picture after subsidizing for the pathological section scanner;
Direct preserving module, if the pathological section pixel for being cut into is equal to the presetted pixel, the pathology is cut Piece scanner directly save described in the pathological section that is cut into;
Parse splicing module, for the pathological section scanner to after described subsidize blank picture and be cut into etc. In the pathological section of the presetted pixel, is parsed and spliced;
Generation module is scanned, parsing and spliced pathological section are scanned for the pathological section scanner, Generate pathological section entirety picture.
Optionally, the scanning blank subsidizes module and includes:
Blank submodule is scanned, scans the blank picture for the pathological section scanner;
Submodule is subsidized, is subsidized for the pathological section scanner by the pathological section for being less than presetted pixel is cut into The upper left corner of the blank picture.
Optionally, the cutting module includes:
Pixel cuts submodule, for the pathological section scanner according to sequence from left to right, from top to bottom, with 256*256 pixel is successively cut.
Optionally, parsing splicing module includes:
Direct splicing submodule, if there was only one for the blank picture number after described subsidize, the pathological section Scanner directly splices the blank picture after described subsidize and the pathological section equal to the presetted pixel being cut into;
Parsing splicing submodule, if being greater than one for the blank picture number after described subsidize, the pathological section Position pass between blank picture and the pathological section equal to the presetted pixel that is cut into after being subsidized described in scanner parsing System, then spliced.
The embodiment of the invention also provides a kind of system for generating picture, the system is applied to medical field, the system System includes: pathological section scanner and pathological section, and the pathological section scanner is for realizing the process described above.
Compared with prior art, the method, apparatus and system of a kind of method generating picture provided by the invention, according to Presetted pixel cuts pathological section, judges whether the pathological section pixel being cut into is less than presetted pixel, if being less than, The blank picture for then creating a presetted pixel will be cut into the pathological section for being less than presetted pixel and subsidize blank sheet on piece, It is parsed and is spliced with the pathological section for being equal to presetted pixel again, ultimately produce pathological section entirety picture, the entirety picture Completely, clearly, edge zone will not be stretched, will not metamorphopsic distortion, improve medical personnel located and sufferer illness examined Disconnected correctness.
Detailed description of the invention
In order to illustrate the technical solution of the embodiments of the present invention more clearly, below by institute in the description to the embodiment of the present invention Attached drawing to be used is needed to be briefly described, it should be apparent that, the accompanying drawings in the following description is only some implementations of the invention Example, for those of ordinary skill in the art, without any creative labor, can also be according to these attached drawings Obtain other attached drawings.
Fig. 1 is a kind of flow chart for generating picture approach of the embodiment of the present invention;
Fig. 2 is the specific flow chart of step 102 in the embodiment of the present invention;
Fig. 3 is the specific flow chart of step 105 in the embodiment of the present invention;
Fig. 4 is the specific flow chart of step 108 in the embodiment of the present invention;
Fig. 5 is another flow chart for generating picture approach in the embodiment of the present invention after step 109;
Fig. 6 is the equipment of the embodiment of the present invention schematic diagram;
Fig. 7 is that only have one to put up after benefit in the case of blank picture in the embodiment of the present invention, pathological section cutting schematic diagram and Pathological section entirety picture schematic diagram;
Fig. 8 is pathological section cutting schematic diagram and disease in the case of having multiple to subsidize rear blank picture in the embodiment of the present invention Reason is sliced whole picture schematic diagram.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are some of the embodiments of the present invention, instead of all the embodiments.Based on this hair Embodiment in bright, every other implementation obtained by those of ordinary skill in the art without making creative efforts Example, shall fall within the protection scope of the present invention.
Fig. 1 shows a kind of flow chart for generating picture approach of the embodiment of the present invention, and this method is applied to medical field, doctor Treatment field includes: pathological section scanner, and pathological section scanner is to generate the smart machine of pathological section digital information The method of picture includes the following steps:
Step 101: pathological section scanner receives pathological section.
In the embodiment of the present invention, pathological section scanner is to digitize pathological section scanner with high precision instead of traditional Microscope realizes the digital information of traditional pathological section, and the picture clarity for generating pathological section is micro- much higher than tradition The picture that mirror mode generates, and pathological section is a kind of conventional means medically used, under normal circumstances, when pathological section system After performing, it is necessary to observational study is carried out to it, to obtain the state of an illness as a result, the present invention be replaced with pathological section scanner it is micro- Mirror, then pathological section scanner receives pathological section.The embodiment of the present invention does not limit this in detail, can be according to the actual situation It is configured.
Step 102: pathological section scanner cuts pathological section according to presetted pixel.
In the embodiment of the present invention, after receiving pathological section, pathological section scanner is to pathological section according to preset Pixel is cut, it should be noted that and it is picture cutting that described cutting, which refers to, in the embodiment of the present invention, because pathological section Particular/special requirement needs to obtain the higher picture of clarity, so needing to be cut with certain pixel size.The present invention is implemented Example does not limit this in detail, can be configured according to the actual situation.
Optionally, referring to Fig. 2, step 102 is specifically included:
Step 102a: pathological section scanner is according to sequence from left to right, from top to bottom, successively with 256*256 pixel It is cut.
In the embodiment of the present invention, pathological section scanner to the cutting of pathological section need according to from left to right, on to Under sequence, successively carried out with 256*256 pixel, obtain one piece one piece of the picture using the pixel as size, these pictures close Get up, the picture of last available entire pathological section, the advantage of doing so is that making pathological section scanner in subsequent solution Analysis and splicing during, can be more efficient obtain complete pathological section picture.The embodiment of the present invention is not made this in detail It limits, can be configured according to the actual situation.
Step 103: whether the pathological section pixel that pathological section scanner judgement is cut into is less than presetted pixel.
In the embodiment of the present invention, during being cut to pathological section according to presetted pixel, often it is cut into one and presets The pathological section of pixel size, just judges whether the pathological section pixel is less than presetted pixel, i.e., whether is less than 256*256 picture Element, it should be noted that when pathological section scanner is cut with presetted pixel in sequence in the embodiment of the present invention, when cutting It may only some be pathological section, another part within the scope of presetted pixel when cutting the edge of pathological section It is not pathological section, that is, is judged as this and is cut into pathological section pixel less than presetted pixel.The embodiment of the present invention is not made this in detail It is thin to limit, it can be configured according to the actual situation.
Step 104: if the pathological section pixel being cut into is less than presetted pixel, pathological section scanner creates a sky The pixel of white picture, blank picture is equal to presetted pixel.
In the embodiment of the present invention, when the pathological section pixel that judgement is cut into is less than presetted pixel, then pathological section is scanned Instrument will automatically create a blank picture, and the pixel of the blank picture is equal to presetted pixel, i.e. the blank picture is 256*256 picture Plain size.The embodiment of the present invention does not limit this in detail, can be configured according to the actual situation.
Step 105: pathological section scanner subsidizes blank sheet on piece for the pathological section for being less than presetted pixel is cut into.
In the embodiment of the present invention, after creating 256*256 pixel size blank picture, pathological section scanner cuts front The pathological section less than 256*256 pixel size cut out subsidizes the blank sheet on piece of creation, and so-called subsidize refers to one Picture is covered on another picture, in embodiments of the present invention, that is, is referred to and is less than 256*256 pixel size for what is be cut into Pathological section, be covered on blank picture, because blank picture is bigger than the pathological section being cut into, be cut into The place that pathological section is not covered with is still blank.The embodiment of the present invention does not limit this in detail, can be according to reality Border situation is configured.
Optionally, referring to Fig. 3, step 105 specifically comprises the following steps:
Step 105a: pathological section scanner scans blank picture.
In the embodiment of the present invention, pathological section scanner is after the blank picture of 256*256 pixel size is opened in creation one, meeting Single pass is carried out to the blank picture of creation, determines that it is 256*256 pixel size again.The embodiment of the present invention does not make this It limits, can be configured according to the actual situation in detail.
Step 105b: pathological section scanner subsidizes blank picture for the pathological section for being less than presetted pixel is cut into The upper left corner.
It is 256*256 pixel in the blank picture size for determining creation, pathological section scanner will in the embodiment of the present invention It is cut into the upper left corner for subsidizing blank picture less than the pathological section of presetted pixel, i.e., will be less than 256*256 pixel size Pathological section subsidizes the upper left corner of blank picture, and such purpose is ultimately produced for subsequent parsing and splicing picture Pathological section entirety picture is complete is coherent, if the position subsidized not in the upper left corner, then the pathological section ultimately produced is whole Picture is just discontinuous in marginal position, has and is left white, and may will affect medical personnel located and judge the state of an illness.The embodiment of the present invention pair This is not limited in detail, can be configured according to the actual situation.
Step 106: pathological section scanner saves the blank picture after subsidizing.
In the embodiment of the present invention, in the upper left that the pathological section for being less than 256*256 pixel size is subsidized to blank picture Behind angle, pathological section scanner saves the blank picture.The embodiment of the present invention does not limit this in detail, can be according to reality Situation is configured.
Step 107: if the pathological section pixel being cut into is equal to presetted pixel, pathological section scanner is directly saved and is cut The pathological section cut out.
In the embodiment of the present invention, if the pathological section pixel being cut into sequence is equal to presetted pixel, i.e. 256*256 It is entirely pathological section within the scope of pixel size, then pathological section scanner directly saves the pathological section being cut into.This hair Bright embodiment does not limit this in detail, can be configured according to the actual situation.
Step 108: pathological section scanner is to the blank picture after subsidizing and the pathology equal to presetted pixel being cut into Slice, is parsed and is spliced.
In the embodiment of the present invention, pathological section scanner in sequence all cuts entire pathological section with presetted pixel After the completion, the blank picture after just having multiple pathological sections equal to presetted pixel saved and subsidizing, pathological section are swept Instrument is retouched to need that these pictures are parsed and spliced.The embodiment of the present invention does not limit this in detail, can be according to practical feelings Condition is configured.
Optionally, referring to Fig. 4, step 108 is specifically included:
Step 108a: if the blank picture number after subsidizing only has one, pathological section scanner directly to subsidizing after Blank picture and the pathological section equal to presetted pixel that is cut into spliced;
In the embodiment of the present invention, pathological section scanner save multiple pathological sections equal to presetted pixel with subsidize after Blank picture in, if only one put up mend after blank picture, then pathological section scanner according to cutting when sequence, it is right Above-mentioned picture is directly spliced, because the pathological section for being less than 256*256 pixel size is subsidized in the upper left of blank picture Angle, so the pathological section entirety picture generated after splicing will not be left white.The embodiment of the present invention does not limit this in detail, can To be configured according to the actual situation.
Step 108b: if the blank picture number after subsidizing is greater than one, after pathological section scanner parsing is subsidized Positional relationship between blank picture and the pathological section equal to presetted pixel being cut into, then spliced.
In the embodiment of the present invention, pathological section scanner save multiple pathological sections equal to presetted pixel with subsidize after Blank picture in, if the blank picture after thering are multiple to subsidize, then pathological section scanner according to cutting when sequence, to upper It states picture to be parsed, parse the blank picture after multiple are subsidized and is closed equal to the position between the pathological section of presetted pixel System, multiple subsidize the positional relationship between rear blank picture, and subsidize the positional relationship that rear picture is left white section, carry out later Splicing, guarantees not have in the pathological section entirety picture being subsequently generated and is left white.The embodiment of the present invention does not limit this in detail It is fixed, it can be configured according to the actual situation.
Step 109: pathological section scanner is scanned parsing and spliced pathological section, and it is whole to generate pathological section Body picture.
In the embodiment of the present invention, pathological section scanner is after the completion of parsing and splicing, to parsing and spliced pathology Slice is scanned, just generate pathological section entirety picture, the entirety picture is complete, clearly, edge zone will not be stretched, Will not metamorphopsic distortion, improve medical personnel located to the diagnosis correctness of sufferer illness.The embodiment of the present invention is not made this in detail It is thin to limit, it can be configured according to the actual situation.
Optionally, referring to Fig. 5, after step 109, the method for generating picture further includes following steps:
Step 110: if pathological section entirety picture does not meet default picture, pathological section scanner is to be higher than 256* 256 pixels are presetted pixel, repeat approach described above, regenerate pathological section entirety picture, and it is clear complete for presetting picture The whole picture for showing pathology.
In the embodiment of the present invention, after generating pathological section entirety picture, if it does not meet default picture, that is, generate Pathological section entirety picture is unable to that complete display shows pathology or medical personnel located, sufferer need pixel higher, clarity Better picture, then pathological section scanner repeats approach described above to be higher than 256*256 pixel as presetted pixel, such as Using 512*512 pixel as presetted pixel, Lai Shengcheng picture.The embodiment of the present invention does not limit this in detail, can be according to reality Situation is configured.
Step 111: if pathological section entirety picture metamorphopsic distortion, pathological section scanner repeats approach described above, Regenerate pathological section entirety picture.
In the embodiment of the present invention, pathological section scanner is during generating pathological section entirety picture, because of each side The factor in face, such as equipment component aging, external human interference etc. may cause the pathological section entirety picture ultimately generated and become Shape distortion, then after removing various factors, pathological section scanner repeats saying described above, regenerates pathological section entirety Picture.The embodiment of the present invention does not limit this in detail, can be configured according to the actual situation.
With reference to the accompanying drawing, method of the invention is further detailed, as shown in fig. 6, showing of the invention real The equipment schematic diagram for applying example, including: pathological section 1, pathological section scanner 2, the scanning area 3 of pathological section scanner, Pathological section scanner 2 has been debugged first with operation control zone 4 in the operation control zone 4 of pathological section scanner, and setting is default Pixel 256*256 needs to be put into pathological section scanner 2, it should be noted that general after pathological section 1 is made 1 actual physics area of pathological section is smaller, and the scanning area 3 of pathological section scanner 2 can put down pathological section 1, if but disease Reason 1 actual physics area of slice is greater than the scanning area 3 of pathological section scanner 2, then needs replacing scanning area and cut greater than pathology The pathological section scanner of piece actual physics area, otherwise pathological section scanner 2 can not complete scan pathological section 1.
Pathological section scanner 2 to pathological section 1 according to sequence from left to right, from top to bottom, with 256*256 pixel according to It is secondary to be cut, it will multiple pathological sections are respectively cut out, are completed until entire pathological section 1 is all cut, herein mistake Cheng Zhong, because being cut according to sequence from left to right, from top to bottom, only exists when cutting to marginal position The rightmost of pathological section 1 and it is likely to the case where will appear less than 256*256 pixel size bottom, it certainly may also will not There is the case where being less than 256*256 pixel size, if the pathological section pixel being cut into is less than 256*256 pixel size, disease The blank picture that slice scanner 2 creates a 256*256 pixel size is managed, pathological section scanner 2 will be less than 256*256 picture The pathological section of plain size subsidizes the upper left corner of the blank picture of 256*256 pixel size, and saves the blank sheet after subsidizing Piece, because the pathological section pixel that other positions are cut into is equal to 256*256 pixel size, so pathological section scanner 2 is direct Save the pathological section of 256*256 pixel size.
After pathological section scanner 2 is completed to the cutting of pathological section 1, if only one puts up the blank picture after mending, Sequence when then pathological section scanner 2 is according to cutting, directly splices above-mentioned picture, because being less than 256*256 pixel The pathological section of size is to subsidize in the upper left corner of blank picture, so the pathological section entirety picture generated after splicing will not have It is left white, as shown in Fig. 7 (1), the square that dotted line is constituted is 256*256 pixel size, and oblique line portion is that pathological section 1 is whole Picture, the part that left side dotted line constitutes square 1 is the pathological section for being equal to 256*256 pixel size, the right pathological section Only some within the scope of 256*256 pixel size, it is that will be less than 256*256 pixel size that dotted line, which constitutes square 2, Pathological section subsidizes the state after the blank picture for being equal to 256*256 pixel size, due to there was only the blank puted up after mending Picture is completed shown in pathological section entirety picture such as Fig. 7 (2) so pathological section scanner 2 directly splices it, should Pathological section entirety picture is complete is clear, and edge zone is not stretched, and does not have metamorphopsic distortion.
If the blank picture after having multiple to subsidize, then pathological section scanner 2 is according to sequence when cutting, to above-mentioned figure Piece is parsed, and parses the blank picture after multiple are subsidized and equal to the positional relationship between the pathological section of presetted pixel, more The positional relationship after mending between blank picture is puted up, and subsidizes the positional relationship that rear picture is left white section, is spliced later, Guarantee not have in the pathological section entirety picture being subsequently generated and be left white, as shown in Fig. 8 (1), the square that dotted line is constituted is For 256*256 pixel size, oblique line portion is pathological section entirety picture, and the part that upper left corner dotted line constitutes square 1 is Equal to the pathological section of 256*256 pixel size, upper right corner pathological section only some in 256*256 pixel size range Interior, it is to subsidize the pathological section for being less than 256*256 pixel size big equal to 256*256 pixel that dotted line, which constitutes square 2, State after small blank picture, also only some is within the scope of 256*256 pixel size for lower left corner pathological section, dotted line structure It is to subsidize the pathological section for being less than 256*256 pixel size in the blank sheet for being equal to 256*256 pixel size at square 3 State after piece, equally also only some is within the scope of 256*256 pixel size for lower right corner pathological section, dotted line composition pros Shape 4 is to subsidize the pathological section for being less than 256*256 pixel size after the blank picture for being equal to 256*256 pixel size State, due to have three put up mend after blank picture, so pathological section scanner 2 parse this three put up mend after blank picture Positional relationship between the pathological section of 256*256 pixel size, three put up the positional relationship after mended between blank picture, with And the positional relationship that rear picture is left white section is subsidized, spliced later, completed shown in pathological section entirety picture such as Fig. 8 (2), The pathological section entirety picture is complete is clear, and edge zone is not stretched, and does not have metamorphopsic distortion.
The embodiment of the invention also provides a kind of device for generating picture, which is applied to medical field, medical field It include: pathological section scanner, pathological section scanner is that the smart machine of pathological section digital information is generated picture dress It sets and includes:
Receiving module receives pathological section for pathological section scanner;
Cutting module cuts pathological section according to presetted pixel for pathological section scanner;
Whether judgment module, the pathological section pixel being cut into for pathological section scanner judgement are less than presetted pixel;
Creation module, if the pathological section pixel for being cut into is less than presetted pixel, pathological section scanner creation The pixel of one blank picture, blank picture is equal to presetted pixel;
Scanning blank subsidizes module, subsidizes for pathological section scanner by the pathological section for being less than presetted pixel is cut into To blank sheet on piece;
Preserving module saves the blank picture after subsidizing for pathological section scanner;
Direct preserving module, if the pathological section pixel for being cut into is equal to presetted pixel, pathological section scanner Directly save the pathological section being cut into;
Splicing module is parsed, default picture is equal to what is be cut into the blank picture after subsidizing for pathological section scanner The pathological section of element, is parsed and is spliced;
Generation module is scanned, parsing and spliced pathological section are scanned for pathological section scanner, generated Pathological section entirety picture.
Optionally, scanning blank subsidizes module and includes:
Blank submodule is scanned, scans blank picture for pathological section scanner;
Submodule is subsidized, subsidizes blank for the pathological section for being less than presetted pixel is cut into for pathological section scanner The upper left corner of picture.
Optionally, cutting module includes:
Pixel cuts submodule, for pathological section scanner according to sequence from left to right, from top to bottom, with 256* 256 pixels are successively cut.
Optionally, parsing splicing module includes:
Direct splicing submodule, if the blank picture number for after subsidizing only has one, pathological section scanner is straight It connects and the blank picture after subsidizing and the pathological section equal to presetted pixel being cut into is spliced;
Parsing splicing submodule, if being greater than one for the blank picture number after subsidizing, pathological section scanner solution Positional relationship between the blank picture after subsidizing and the pathological section equal to presetted pixel being cut into is analysed, then is spliced.
The embodiment of the invention also provides a kind of system for generating picture, which is applied to medical field, the system packet Include: pathological section scanner and pathological section, wherein pathological section scanner is for realizing the process described above.
Through the foregoing embodiment, the present invention cuts pathological section according to presetted pixel, judges the pathology being cut into Whether slice pixel is less than presetted pixel, if being less than, creates the blank picture of a presetted pixel, will be cut into and be less than in advance If the pathological section of pixel subsidizes blank sheet on piece, then is parsed and spliced with the pathological section for being equal to presetted pixel, most Afterwards generate pathological section entirety picture, the entirety picture is complete, clearly, edge zone will not be stretched, will not metamorphopsic distortion, Medical personnel located is improved to the diagnosis correctness of sufferer illness.
Finally, it is to be noted that, herein, relational terms such as first and second and the like be used merely to by One entity or operation are distinguished with another entity or operation, without necessarily requiring or implying these entities or operation Between there are any actual relationship or orders.Moreover, herein, the terms "include", "comprise" or its it is any its He is intended to non-exclusive inclusion by variant, so that process, method, article or device including a series of elements are not Only include those elements, but also including other elements that are not explicitly listed, or further include for this process, method, Article or the intrinsic element of device.In the absence of more restrictions, being wanted by what sentence "including a ..." limited Element, it is not excluded that there is also other identical elements in process, method, article or the device for including the element.
The embodiment of the present invention is described with above attached drawing, but the invention is not limited to above-mentioned specific Embodiment, the above mentioned embodiment is only schematical, rather than restrictive, those skilled in the art Under the inspiration of the present invention, without breaking away from the scope protected by the purposes and claims of the present invention, it can also make very much Form, all of these belong to the protection of the present invention.

Claims (10)

1. a kind of method for generating picture, which is characterized in that the method is applied to medical field, and the medical field includes: Pathological section scanner, the pathological section scanner are by the smart machine of pathological section digital information, the method packet It includes:
The pathological section scanner receives pathological section;
The pathological section scanner cuts the pathological section according to presetted pixel;
Whether the pathological section pixel that the pathological section scanner judgement is cut into is less than the presetted pixel;
If the pathological section pixel being cut into is less than the presetted pixel, the pathological section scanner creates a sky The pixel of white picture, the blank picture is equal to the presetted pixel;
The pathological section scanner subsidizes the blank sheet on piece for the pathological section for being less than the presetted pixel is cut into;
The pathological section scanner saves the blank picture after subsidizing;
If the pathological section pixel being cut into is equal to the presetted pixel, the pathological section scanner directly saves institute State the pathological section being cut into;
The pathological section scanner is to the blank picture after described subsidize and the pathology equal to the presetted pixel being cut into Slice, is parsed and is spliced;
The pathological section scanner is scanned parsing and spliced pathological section, generates pathological section entirety picture.
2. the method according to claim 1, wherein the pathological section scanner will be cut into it is pre- less than described If the pathological section of pixel subsidizes the blank sheet on piece, comprising:
The pathological section scanner scans the blank picture;
The pathological section scanner subsidizes the upper left of the blank picture by the pathological section less than presetted pixel is cut into Angle.
3. the method according to claim 1, wherein the pathological section scanner to the pathological section according to Presetted pixel is cut, comprising:
The pathological section scanner is successively cut according to sequence from left to right, from top to bottom with 256*256 pixel.
4. the method according to claim 1, wherein the pathological section scanner is to the blank picture after subsidizing The pathological section equal to the presetted pixel with being cut into, is parsed and is spliced, comprising:
If it is described subsidize after blank picture number there was only one, the pathological section scanner directly to described subsidize after Blank picture and the pathological section equal to the presetted pixel being cut into are spliced;
If it is described subsidize after blank picture number be greater than one, the sky after being subsidized described in pathological section scanner parsing Positional relationship between white picture and the pathological section equal to the presetted pixel being cut into, then spliced.
5. the method according to claim 1, wherein the pathological section scanner to parsing and it is spliced Pathological section is scanned, after generating pathological section entirety picture, the method also includes:
If the pathological section entirety picture does not meet default picture, the pathological section scanner is to be higher than 256*256 picture Element is presetted pixel, repeats claim 1-4 the method, regenerates pathological section entirety picture, the default picture is Complete display shows the picture of pathology;
If the pathological section entirety picture metamorphopsic distortion, the pathological section scanner repeats side described in claim 1-4 Method regenerates pathological section entirety picture.
6. a kind of device for generating picture, which is characterized in that described device is applied to medical field, and the medical field includes: Pathological section scanner, the pathological section scanner are by the smart machine of pathological section digital information, described device packet It includes:
Receiving module receives pathological section for the pathological section scanner;
Cutting module cuts the pathological section according to presetted pixel for the pathological section scanner;
Whether judgment module, the pathological section pixel being cut into for pathological section scanner judgement are less than the default picture Element;
Creation module, if the pathological section pixel for being cut into is less than the presetted pixel, the pathological section scanner A blank picture is created, the pixel of the blank picture is equal to the presetted pixel;
Scanning blank subsidizes module, will be cut into the pathological section for being less than the presetted pixel for the pathological section scanner Subsidize the blank sheet on piece;
Preserving module saves the blank picture after subsidizing for the pathological section scanner;
Direct preserving module, if the pathological section pixel for being cut into is equal to the presetted pixel, the pathological section is swept Retouch instrument directly save described in the pathological section that is cut into;
Splicing module is parsed, institute is equal to what is be cut into the blank picture after described subsidize for the pathological section scanner The pathological section for stating presetted pixel is parsed and is spliced;
Generation module is scanned, parsing and spliced pathological section are scanned for the pathological section scanner, generated Pathological section entirety picture.
7. device according to claim 6, which is characterized in that the scanning blank subsidizes module and includes:
Blank submodule is scanned, scans the blank picture for the pathological section scanner;
Subsidize submodule, for the pathological section scanner will be cut into the pathological section less than presetted pixel subsidize it is described The upper left corner of blank picture.
8. device according to claim 6, which is characterized in that the cutting module includes:
Pixel cuts submodule, for the pathological section scanner according to sequence from left to right, from top to bottom, with 256* 256 pixels are successively cut.
9. device according to claim 6, which is characterized in that parsing splicing module includes:
Direct splicing submodule, if there was only one for the blank picture number after described subsidize, the pathological section scanning Instrument directly splices the blank picture after described subsidize and the pathological section equal to the presetted pixel being cut into;
Parsing splicing submodule, if being greater than one for the blank picture number after described subsidize, the pathological section scanning Positional relationship between blank picture and the pathological section equal to the presetted pixel that is cut into after being subsidized described in instrument parsing, then Spliced.
10. a kind of system for generating picture, which is characterized in that the system is applied to medical field, the system comprises: pathology Slice scanner and pathological section, the pathological section scanner is for realizing method described in claim 1-5.
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CN107493403A (en) * 2017-08-11 2017-12-19 宁波江丰生物信息技术有限公司 A kind of digital pathological section scanning system
CN107563974A (en) * 2017-08-15 2018-01-09 深圳云天励飞技术有限公司 Image de-noising method, device, electronic equipment and storage medium
CN108537730A (en) * 2018-03-27 2018-09-14 宁波江丰生物信息技术有限公司 A kind of image split-joint method

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106408573A (en) * 2016-08-31 2017-02-15 诸暨微因生物科技有限公司 Whole slide digital pathological image processing and analysis method
CN107493403A (en) * 2017-08-11 2017-12-19 宁波江丰生物信息技术有限公司 A kind of digital pathological section scanning system
CN107563974A (en) * 2017-08-15 2018-01-09 深圳云天励飞技术有限公司 Image de-noising method, device, electronic equipment and storage medium
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